Mats Hamberg

Publications
Public outreach and news

Articles

Article: NATURE COMMUNICATIONS. 2023;14(1):539
Dosage differences in 12-OXOPHYTODIENOATE REDUCTASE genes modulate wheat root growth
Gabay G; Wang H; Zhang J; Moriconi JI; Burguener GF; Gualano LD; Howell T; Lukaszewski A; Staskawicz B; Cho M-J; Tanaka J; Fahima T; Ke H; Dehesh K; Zhang G-L; Gou J-Y; Hamberg M; Santa-Maria GE; Dubcovsky J
Article: ANALYTICAL CHEMISTRY. 2022;94(42):14618-14626
Development of a Chiral Supercritical Fluid Chromatography-Tandem Mass Spectrometry and Reversed-Phase Liquid Chromatography-Tandem Mass Spectrometry Platform for the Quantitative Metabolic Profiling of Octadecanoid Oxylipins
Quaranta A; Zohrer B; Revol-Cavalier J; Benkestock K; Balas L; Oger C; Keyes GS; Wheelock AM; Durand T; Galano J-M; Ramsden CE; Hamberg M; Wheelock CE
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(36):e2202930119
Ligand diversity contributes to the full activation of the jasmonate pathway in Marchantia polymorpha
Kneeshaw S; Soriano G; Monte I; Hamberg M; Zamarreno AM; Garcia-Mina JM; Manuel Franco-Zorrilla J; Kato N; Ueda M; Fernanda Rey-Stolle M; Barbas C; Michavila S; Gimenez-Ibanez S; Jimenez-Aleman GH; Solano R
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2021;1866(5):158886
COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells
Johnsson A-K; Ronnberg E; Fuchs D; Kolmert J; Safholm J; Claesson H-E; Hamberg M; Wheelock CE; Nilsson G; Dahlen S-E
Article: JAOCS, JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY. 2021;98(5):489-494
A Facile and Efficient Method for the Synthesis of Labeled and Unlabeled Very Long Chain Polyunsaturated Fatty Acids
Hamberg M
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(4):594-603
Selective inhibition of prostaglandin D₂ biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences
Johnsson A-K; Choi J-H; Ronnberg E; Fuchs D; Kolmert J; Hamberg M; Dahlen B; Wheelock CE; Dahlen S-E; Nilsson G
Article: PLANT AND CELL PHYSIOLOGY. 2020;61(6):1144-1157
Protein Profiles of Lipid Droplets during the Hypersensitive Defense Response of Arabidopsis against Pseudomonas Infection
Fernandez-Santos R; Izquierdo Y; Lopez A; Muniz L; Martinez M; Cascon T; Hamberg M; Castresana C
Article: RAPID COMMUNICATIONS IN MASS SPECTROMETRY. 2020;34(8):e8665
Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates
Oliw EH; Hamberg M
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2020;1865(4):158611
Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent process
Fuchs D; Tang X; Johnsson A-K; Dahlen S-E; Hamberg M; Wheelock CE
Article: LIPIDS. 2019;54(9):543-556
Biosynthesis of Jasmonates from Linoleic Acid by the Fungus Fusarium oxysporum. Evidence for a Novel Allene Oxide Cyclase
Oliw EH; Hamberg M
Article: JOURNAL OF LIPID RESEARCH. 2018;59(10):2025-2033
An LC-MS/MS workflow to characterize 16 regio- and stereoisomeric trihydroxyoctadecenoic acids
Fuchs D; Hamberg M; Skold CM; Wheelock AM; Wheelock CE
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2018;1863(10):1316-1322
Plant hydroperoxide-cleaving enzymes (CYP74 family) function as hemiacetal synthases: Structural proof of hemiacetals by NMR spectroscopy
Mukhtarova LS; Bruhlmann F; Hamberg M; Khairutdinov BI; Grechkin AN
Article: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2018;137:20-29
Prominent release of lipoxygenase generated mediators in a murine house dust mite-induced asthma model
Kolmert J; Pineiro-Hermida S; Hamberg M; Gregory JA; Lopez IP; Fauland A; Wheelock CE; Dahlen S-E; Pichel JG; Adner M
Article: PLANT, CELL AND ENVIRONMENT. 2018;41(6):1438-1452
Arabidopsis nonresponding to oxylipins locus NOXY7 encodes a yeast GCN1 homolog that mediates noncanonical translation regulation and stress adaptation
Izquierdo Y; Kulasekaran S; Benito P; Lopez B; Marcos R; Cascon T; Hamberg M; Castresana C
Article: NATURE CHEMICAL BIOLOGY. 2018;14(5):480-488
Ligand-receptor co-evolution shaped the jasmonate pathway in land plants
Monte I; Ishida S; Zamarreno AM; Hamberg M; Franco-Zorrilla JM; Garcia-Casado G; Gouhier-Darimont C; Reymond P; Takahashi K; Garcia-Mina JM; Nishihama R; Kohchi T; Solano R
Article: NATURE CHEMICAL BIOLOGY. 2018;14(2):171-178
An OPR3-independent pathway uses 4,5-didehydrojasmonate for jasmonate synthesis
Chini A; Monte I; Zamarreno AM; Hamberg M; Lassueur S; Reymond P; Weiss S; Stintzi A; Schaller A; Porzel A; Garcia-Mina JM; Solano R
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2017;1862(10):1099-1109
Identification of CYP443D1 (CYP74 clan) of Nematostella vectensis as a first cnidarian epoxyalcohol synthase and insights into its catalytic mechanism
Toporkova YY; Gorina SS; Mukhitova FK; Hamberg M; Ilyina TM; Mukhtarova LS; Grechkin AN
Article: JOURNAL OF LIPID RESEARCH. 2017;58(8):1670-1680
An allene oxide and 12-oxophytodienoic acid are key intermediates in jasmonic acid biosynthesis by Fusarium oxysporum
Oliw EH; Hamberg M
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2017;1862(5):463-473
The crystal structure of Pseudomonas aeruginosa lipoxygenase Ala420Gly mutant explains the improved oxygen affinity and the altered reaction specificity
Kalms J; Banthiya S; Yoga EG; Hamberg M; Holzhutter H-G; Kuhn H; Scheerer P
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2016;1861(11):1681-1692
Structural and functional basis of phospholipid oxygenase activity of bacterial lipoxygenase from Pseudomonas aeruginosa
Banthiya S; Kalms J; Yoga EG; Ivanov I; Carpena X; Hamberg M; Kuhn H; Scheerer P
Article: JOURNAL OF EXPERIMENTAL BOTANY. 2016;67(17):5133-5144
The activity of HYDROPEROXIDE LYASE 1 regulates accumulation of galactolipids containing 12-oxo-phytodienoic acid in Arabidopsis
Nilsson AK; Fahlberg P; Johansson ON; Hamberg M; Andersson MX; Ellerstrom M
Article: BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS. 2016;26(15):3547-3551
Kinetic investigation of human 5-lipoxygenase with arachidonic acid
Mittal M; Kumar RB; Balagunaseelan N; Hamberg M; Jegerschold C; Radmark O; Haeggstrom JZ; Rinaldo-Matthis A
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2016;1861(2):108-118
Replacement of two amino acids of 9R-dioxygenase-allene oxide synthase of Aspergillus niger inverts the chirality of the hydroperoxide and the allene oxide
Sooman L; Wennman A; Hamberg M; Hoffmann I; Oliw EH
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(4):972-977
A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E₂ synthase
Brock JS; Hamberg M; Balagunaseelan N; Goodman M; Morgenstern R; Strandback E; Samuelsson B; Rinaldo-Matthis A; Haeggstrom JZ
Article: PLOS ONE. 2016;11(4):e0153216
Screen Identifying Arabidopsis Transcription Factors Involved in the Response to 9-Lipoxygenase-Derived Oxylipins
Walper E; Weiste C; Mueller MJ; Hamberg M; Droge-Laser W
Article: PLANT PHYSIOLOGY. 2015;169(3):2324-2334
9-Lipoxygenase-Derived Oxylipins Activate Brassinosteroid Signaling to Promote Cell Wall-Based Defense and Limit Pathogen Infection
Marcos R; Izquierdo Y; Vellosillo T; Kulasekaran S; Cascon T; Hamberg M; Castresana C
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1851(9):1262-1270
Stereospecific biosynthesis of (9S,13S)-10-oxo-phytoenoic acid in young maize roots
Ogorodnikova AV; Gorina SS; Mukhtarova LS; Mukhitova FK; Toporkova YY; Hamberg M; Grechkin AN
Article: JOURNAL OF LIPID RESEARCH. 2015;56(8):1606-1615
Manganese lipoxygenase of F. oxysporum and the structural basis for biosynthesis of distinct 11-hydroperoxy stereoisomers
Wennman A; Magnuson A; Hamberg M; Oliw EH
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(20):6395-6400
Predator lipids induce paralytic shellfish toxins in bloom-forming algae
Selander E; Kubanek J; Hamberg M; Andersson MX; Cervin G; Pavia H
Article: BMC PLANT BIOLOGY. 2015;15:45
The Physcomitrella patens unique alpha-dioxygenase participates in both developmental processes and defense responses
Machado L; Castro A; Hamberg M; Bannenberg G; Gaggero C; Castresana C; de Leon IP
Article: PLANT PHYSIOLOGY. 2014;167(1):251-261
Involvement of the Electrophilic Isothiocyanate Sulforaphane in Arabidopsis Local Defense Responses
Andersson MX; Nilsson AK; Johansson ON; Boztas G; Adolfsson LE; Pinosa F; Petit CG; Aronsson H; Mackey D; Toer M; Hamberg M; Ellerstrom M
Article: NATURE CHEMICAL BIOLOGY. 2014;10(8):671-676
Rational design of a ligand-based antagonist of jasmonate perception
Monte I; Hamberg M; Chini A; Gimenez-Ibanez S; Garcia-Casado G; Porzel A; Pazos F; Boter M; Solano R
Article: JOURNAL OF LIPID RESEARCH. 2014;:jlr.m046052
WITHDRAWN: Structural and mechanistic studies of hydroperoxide conversions catalyzed by a CYP74 clan epoxy alcohol synthase from amphioxus (Branchiostoma floridae).
Hamberg M; Khairutdinov BI; Scholz J; Brodhun F; Hornung E; Feussner I; Grechkin AN
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(45):32405-32413
Diversity of Δ12 Fatty Acid Desaturases in Santalaceae and Their Role in Production of Seed Oil Acetylenic Fatty Acids
Okada S; Zhou X-R; Damcevski K; Gibb N; Wood C; Hamberg M; Haritos VS
Article: PLANT PHYSIOLOGY. 2013;161(2):617-627
Defense Activated by 9-Lipoxygenase-Derived Oxylipins Requires Specific Mitochondrial Proteins
Vellosillo T; Aguilera V; Marcos R; Bartsch M; Vicente J; Cascon T; Hamberg M; Castresana C
Article: PLOS ONE. 2013;8(5):e64919
An Iron 13S-Lipoxygenase with an α-Linolenic Acid Specific Hydroperoxidase Activity from Fusarium oxysporum
Brodhun F; Cristobal-Sarramian A; Zabel S; Newie J; Hamberg M; Feussner I
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1821(12):1508-1517
Novel insights into cyclooxygenases, linoleate diol synthases, and lipoxygenases from deuterium kinetic isotope effects and oxidation of substrate analogs
Hoffmann I; Hamberg M; Lindh R; Oliw EH
Article: PLANT PHYSIOLOGY. 2012;160(3):1251-1266
Crystal Structures of Physcomitrella patens AOC1 and AOC2: Insights into the Enzyme Mechanism and Differences in Substrate Specificity
Neumann P; Brodhun F; Sauer K; Herrfurth C; Hamberg M; Brinkmann J; Scholz J; Dickmanns A; Feussner I; Ficner R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(38):31757-31765
Catalytic Convergence of Manganese and Iron Lipoxygenases by Replacement of a Single Amino Acid
Wennman A; Jerneren F; Hamberg M; Oliw EH
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1821(9):1244-1255
Biochemical characterization of a chloroplast localized fatty acid reductase from Arabidopsis thaliana
Doan TTP; Domergue F; Fournier AE; Vishwanath SJ; Rowland O; Moreau P; Wood CC; Carlsson AS; Hamberg M; Hofvander P
Article: MOLECULAR PLANT. 2012;5(4):914-928
Role of 9-Lipoxygenase and α-Dioxygenase Oxylipin Pathways as Modulators of Local and Systemic Defense
Vicente J; Cascon T; Vicedo B; Garcia-Agustin P; Hamberg M; Castresana C
Article: BMC BIOCHEMISTRY. 2012;13:4
Identification of avian wax synthases
Biester E-M; Hellenbrand J; Gruber J; Hamberg M; Frentzen M
Article: NATURE COMMUNICATIONS. 2012;3:1150
The convergent evolution of defensive polyacetylenic fatty acid biosynthesis genes in soldier beetles
Haritos VS; Horne I; Damcevski K; Glover K; Gibb N; Okada S; Hamberg M
Article: LIPIDS. 2012;47(1):65-73
Linolenate 9R-Dioxygenase and Allene Oxide Synthase Activities of Lasiodiplodia theobromae
Jerneren F; Eng F; Hamberg M; Oliw EH
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(51):20479-20484
Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development
Haas U; Raschperger E; Hamberg M; Samuelsson B; Tryggvason K; Haeggstrom JZ
Article: BMC BIOCHEMISTRY. 2011;12:64
Fatty acyl-CoA reductases of birds
Hellenbrand J; Biester E-M; Gruber J; Hamberg M; Frentzen M
Article: FEBS LETTERS. 2011;585(22):3538-3543
A prokaryotic acyl-CoA reductase performing reduction of fatty acyl-CoA to fatty alcohol
Hofvander P; Doan TTP; Hamberg M
Article: JOURNAL OF LIPID RESEARCH. 2011;52(11):1995-2004
Stereoselective oxidation of regioisomeric octadecenoic acids by fatty acid dioxygenases
Oliw EH; Wennman A; Hoffmann I; Garscha U; Hamberg M; Jerneren F
Article: LIPIDS. 2011;46(9):873-878
Efficient and Specific Conversion of 9-Lipoxygenase Hydroperoxides in the Beetroot. Formation of Pinellic Acid
Hamberg M; Olsson U
Article: THE PLANT JOURNAL. 2011;67(3):447-458
Antagonistic role of 9-lipoxygenase-derived oxylipins and ethylene in the control of oxidative stress, lipid peroxidation and plant defence
Lopez MA; Vicente J; Kulasekaran S; Vellosillo T; Martinez M; Irigoyen ML; Cascon T; Bannenberg G; Hamberg M; Castresana C
Article: INTERNATIONAL JOURNAL OF CANCER. 2011;128(7):1703-1711
Omega-3 fatty acid supplementation delays the progression of neuroblastoma in vivo
Gleissman H; Segerstrom L; Hamberg M; Ponthan F; Lindskog M; Johnsen JI; Kogner P
Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2011;507(1):14-25
The reaction mechanism of allene oxide synthase: Interplay of theoretical QM/MM calculations and experimental investigations
Cho K-B; Lai W; Hamberg M; Raman CS; Shaik S
Article: LIPIDS. 2011;46(2):201-206
Stereochemistry of Hydrogen Removal During Oxygenation of Linoleic Acid by Singlet Oxygen and Synthesis of 11(S)-Deuterium-Labeled Linoleic Acid
Hamberg M
Article: LIPIDS. 2011;46(1):69-79
Biosynthesis of 14,15-Hepoxilins in Human L1236 Hodgkin Lymphoma Cells and Eosinophils
Brunnstrom A; Hamberg M; Griffiths WJ; Mannervik B; Claesson H-E
Article: PLANT PHYSIOLOGY. 2010;154(2):444-448
Emerging Complexity in Reactive Oxygen Species Production and Signaling during the Response of Plants to Pathogens
Vellosillo T; Vicente J; Kulasekaran S; Hamberg M; Castresana C
Article: JOURNAL OF MOLECULAR MEDICINE. 2010;88(8):795-806
Thromboxane synthase expression and thromboxane A₂ production in the atherosclerotic lesion
Gabrielsen A; Qiu H; Back M; Hamberg M; Hemdahl A-L; Agardh H; Folkersen L; Swedenborg J; Hedin U; Paulsson-Berne G; Haeggstrom JZ; Hansson GK
Article: BIOCHEMISTRY (MOSCOW). 2010;75(6):708-716
Hexadecanoid pathway in plants: Lipoxygenase dioxygenation of (7Z,10Z,13Z)-hexadecatrienoic acid
Osipova EV; Lantsova NV; Chechetkin IR; Mukhitova FK; Hamberg M; Grechkin AN
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(19):14178-14186
A Bisallylic Mini-lipoxygenase from Cyanobacterium Cyanothece sp That Has an Iron as Cofactor
Andreou A; Goebel C; Hamberg M; Feussner I
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1801(4):503-507
Reaction mechanism of 5,8-linoleate diol synthase, 10R-dioxygenase, and 8,11-hydroperoxide isomerase of Aspergillus clavatus
Jerneren F; Garscha U; Hoffmann I; Hamberg M; Oliw EH
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(13):9339-9345
Biochemical Characterization of the Oxygenation of Unsaturated Fatty Acids by the Dioxygenase and Hydroperoxide Isomerase of Pseudomonas aeruginosa 42A2
Martinez E; Hamberg M; Busquets M; Diaz P; Manresa A; Oliw EH
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(8):5308-5316
Gene Deletion of 7,8-Linoleate Diol Synthase of the Rice Blast Fungus STUDIES ON PATHOGENICITY, STEREOCHEMISTRY, AND OXYGENATION MECHANISMS
Jerneren F; Sesma A; Francheschetti M; Hamberg M; Oliw EH
Article: PLANTA. 2010;231(3):717-728
A tomato enzyme synthesizes (+)-7-iso-jasmonoyl-l-isoleucine in wounded leaves
Suza WP; Rowe ML; Hamberg M; Staswick PE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;390(3):780-785
The crystal structure of oxylipin-conjugated barley LTP1 highlights the unique plasticity of the hydrophobic cavity of these plant lipid-binding proteins
Bakan B; Hamberg M; Larue V; Prange T; Marion D; Lascombe M-B
Article: PLANT PHYSIOLOGY. 2009;151(3):1421-1432
Functional Analysis of α-DOX2, an Active α-Dioxygenase Critical for Normal Development in Tomato Plants
Bannenberg G; Martinez M; Jose Rodriguez M; Angel Lopez M; Ponce de Leon I; Hamberg M; Castresana C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(44):18757-18762
Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells
Hanaka H; Pawelzik S-C; Johnsen JI; Rakonjac M; Terawaki K; Rasmuson A; Sveinbjornsson B; Schumacher MC; Hamberg M; Samuelsson B; Jakobsson P-J; Kogner P; Radmark O
Article: BIOCHEMISTRY (MOSCOW). 2009;74(8):855-861
Specificity of oxidation of linoleic acid homologs by plant lipoxygenases
Chechetkin IR; Osipova EV; Tarasova NB; Mukhitova FK; Hamberg M; Gogolev YV; Grechkin AN
Article: JOURNAL OF PLANT PHYSIOLOGY. 2009;166(8):787-796
Functional expression of five Arabidopsis fatty acyl-CoA reductase genes in Escherichia coli
Doan TTP; Carlsson AS; Hamberg M; Bulow L; Stymne S; Olsson P
Article: NATURE CHEMICAL BIOLOGY. 2009;5(5):344-350
(+)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate
Fonseca S; Chini A; Hamberg M; Adie B; Porzel A; Kramell R; Miersch O; Wasternack C; Solano R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2009;284(12):8005-8012
On the Mechanism of a Polyunsaturated Fatty Acid Double Bond Isomerase from Propionibacterium acnes
Liavonchanka A; Rudolph MG; Tittmann K; Hamberg M; Feussner I
Article: LIPIDS. 2009;44(2):85-95
Diversity of the Enzymatic Activity in the Lipoxygenase Gene Family of Arabidopsis thaliana
Bannenberg G; Martinez M; Hamberg M; Castresana C
Article: SCIENCE. 2009;323(5911):262-265
tasselseed1 Is a Lipoxygenase Affecting Jasmonic Acid Signaling in Sex Determination of Maize
Acosta IF; Laparra H; Romero SP; Schmelz E; Hamberg M; Mottinger JP; Moreno MA; Dellaporta SL
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2009;284(1):301-305
Mutation of a Critical Arginine in Microsomal Prostaglandin E Synthase-1 Shifts the Isomerase Activity to a Reductase Activity That Converts Prostaglandin H₂ into Prostaglandin F_2α
Hammarberg T; Hamberg M; Wetterholm A; Hansson H; Samuelsson B; Haeggstrom JZ
Article: CHEMBIOCHEM. 2008;9(15):2498-2505
Tomato CYP74C3 is a Multifunctional Enzyme not only Synthesizing Allene Oxide but also Catalyzing its Hydrolysis and Cyclization
Grechkin AN; Mukhtarova LS; Latypova LR; Gogolev Y; Toporkova YY; Hamberg M
Article: NATURE. 2008;455(7211):363-368
Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes
Lee D-S; Nioche P; Hamberg M; Raman CS
Article: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2008;56(17):7983-7991
Analysis of oil composition in cultivars and wild species of oat (Avena sp.)
Leonova S; Shelenga T; Hamberg M; Konarev AV; Loskutov I; Carlsson AS
Article: PROTEINS: STRUCTURE, FUNCTION AND BIOINFORMATICS. 2008;72(4):1199-1211
Evidence for communality in the primary determinants of CYP74 catalysis and of structural similarities between CYP74 and classical mammalian P450 enzymes
Hughes RK; Yousafzai FK; Ashton R; Chechetkin IR; Fairhurst SA; Hamberg M; Casey R
Article: PHYTOCHEMISTRY. 2008;69(10):2008-2015
A lipoxygenase-divinyl ether synthase pathway in flax (Linum usitatissimum L.) leaves
Chechetkin IR; Blufard A; Hamberg M; Grechkin AN
Article: THE PLANT JOURNAL. 2008;54(2):236-248
Enzymatic, but not non-enzymatic, ¹O₂-mediated peroxidation of polyunsaturated fatty acids forms part of the EXECUTER1-dependent stress response program in the flu mutant of Arabidopsis thaliana
Przybyla D; Goebel C; Imboden A; Hamberg M; Feussner I; Apel K
Article: PLANT PHYSIOLOGY. 2007;145(4):1658-1669
Oxo-phytodienoic acid-containing galactolipids in arabidopsis:: Jasmonate signaling dependence
Kourtchenko O; Andersson MX; Hamberg M; Brunnstrom A; Goebel C; McPhail KL; Gerwick WH; Feussner I; Ellerstrom M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(48):34707-34718
Identification of dioxygenases required for aspergillus development -: Studies of products, stereochemistry, and the reaction mechanism
Garscha U; Jerneren F; Chung D; Keller NP; Hamberg M; Oliw EH
Article: THE PLANT CELL. 2007;19(3):831-846
Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade
Vellosillo T; Martinez M; Lopez MA; Vicente J; Cascon T; Dolan L; Hamberg M; Castresana C
Article: JOURNAL OF LIPID RESEARCH. 2007;48(4):976-987
Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols
Karu K; Hornshaw M; Woffendin G; Bodin K; Hamberg M; Alvelius G; Sjovall J; Turton J; Wang Y; Griffiths WJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(51):38981-38988
Specific adduction of plant lipid transfer protein by an allene oxide generated by 9-lipoxygenase and allene oxide synthase
Bakan B; Hamberg M; Perrocheau L; Maume D; Rogniaux H; Tranquet O; Rondeau C; Blein J-P; Ponchet M; Marion D
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2006;1761(12):1419-1428
Hydroperoxide lyases (CYP74C and CYP74B) catalyze the homolytic isomerization of fatty acid hydroperoxides into hemiacetals
Grechkin AN; Bruehlmann F; Mukhtarova LS; Gogolev YV; Hamberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(42):31528-31537
Oxylipin profiling of the hypersensitive response in Arabidopsis thaliana -: Formation of a novel oxo-phytodienoic acid-containing galactolipid, arabidopside E
Andersson MX; Hamberg M; Kourtchenko O; Brunnstrom A; McPhail KL; Gerwick WH; Goebel C; Feussner I; Ellerstrom M
Article: JOURNAL OF CHROMATOGRAPHY A. 2006;1115(1-2):253-259
Characterization of anacardic acids by micellar electrokinetic chromatography and mass spectrometry
Cesla P; Blomberg L; Hamberg M; Jandera P
Article: LIPIDS. 2006;41(5):499-506
Synthesis of 3-oxalinolenic acid and β-oxidation-resistant 3-oxa-oxylipins
Hamberg M; Chechetkin IR; Grechkin AN; de Leon IP; Castresana C; Bannenberg G
Article: PLANT PHYSIOLOGY. 2005;139(4):1902-1913
Evaluation of the antimicrobial activities of plant oxylipins supports their involvement in defense against pathogens
Prost I; Dhondt S; Rothe G; Vicente J; Rodriguez MJ; Kift N; Carbonne F; Griffiths G; Esquerré-Tugayé MT; Rosahl S; Castresana C; Hamberg M; Fournier J
Article: CHEMISTRY AND PHYSICS OF LIPIDS. 2005;138(1-2):93-101
Thermal conversions of trimethylsilyl peroxides of linoleic and linolenic acids
Grechkin AN; Mukhtarova LS; Hamberg M
Article: LIPIDS. 2005;40(11):1163-1170
Conversion of linoleic acid into novel Oxylipins by the mushroom Agaricus bisporus
Wadman MW; van Zadelhoff G; Hamberg M; Visser T; Veldink GA; Vliegenthart JFG
Article: LIPIDS. 2005;40(3):249-257
Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase-10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid
Butovich IA; Hamberg M; Rådmark O
Article: THE FEBS JOURNAL. 2005;272(3):736-743
Hidden stereospecificity in the biosynthesis of divinyl ether fatty acids
Hamberg M
Article: THE FEBS JOURNAL. 2004;271(14):2991-2997
Properties of two multifunctional plant fatty acid acetylenase/desaturase enzymes
Carlsson AS; Thomaeus S; Hamberg M; Stymne S
Article: LIPIDS. 2004;39(6):565-569
Isolation and structures of two divinyl ether fatty acids from Clematis vitalba
Hamberg M
Article: LIPIDS. 2004;39(4):319-323
Biosynthesis and isomerization of 11-hydroperoxylinoleates by manganese- and iron-dependent lipoxygenases
Oliw EH; Cristea M; Hamberg M
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2004;1636(1):47-58
The "heterolytic hydroperoxide lyase" is an isomerase producing a short-lived fatty acid hemiacetal
Grechkin AN; Hamberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(51):51796-51805
Activation of the fatty acid α-dioxygenase pathway during bacterial infection of tobacco leaves -: Formation of oxylipins protecting against cell death
Hamberg M; Sanz A; Rodriguez MJ; Calvo AP; Castresana C
Article: FEBS LETTERS. 2003;549(1-3):31-34
Detection of an enol intermediate in the hydroperoxide lyase chain cleavage reaction
Grechkin AN; Mukhtarova LS; Hamberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(25):22199-22209
Human microsomal prostaglandin E synthase-1 -: Purification, functional characterization, and projection structure determination
Thorén S; Weinander R; Saha S; Jegerschöld C; Pettersson PL; Samuelsson B; Hebert H; Hamberg M; Morgenstern R; Jakobsson PJ
Article: PHYTOCHEMISTRY. 2003;63(1):89-95
Screening of oxylipins for control of oilseed rape (Brassica napus) fungal pathogens
Granér G; Hamberg M; Meijer J
Article: CHEMISTRY AND PHYSICS OF LIPIDS. 2002;120(1-2):87-99
Role of structure and pH in cyclization of allene oxide fatty acids: Implications for the reaction mechanism
Grechkin AN; Chechetkin IR; Mukhtarova LS; Hamberg M
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2002;1584(1):55-64
Oxylipin profiling in pathogen-infected potato leaves
Göbel C; Feussner I; Hamberg M; Rosahl S
Article: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2002;68-9:363-374
Fatty acid α-dioxygenases
Hamberg M; de León IP; Sanz A; Castresana C
Article: JOURNAL OF SEPARATION SCIENCE. 2002;25(8):499-506
Separation of conjugated linoleic acid isomers and parinaric fatty acid isomers by capillary electrophoresis
Öhman M; Wan H; Hamberg M; Blomberg LG
Article: LIPIDS. 2002;37(4):427-433
Biosynthesis of new divinyl ether oxylipins in Ranunculus plants
Hamberg M
Article: THE PLANT JOURNAL. 2002;29(1):61-62
Involvement of the Arabidopsis α-DOX1 fatty acid dioxygenase in protection against oxidative stress and cell death
de Leon IP; Sanz A; Hamberg M; Castresana C
Article: ELECTROPHORESIS. 2001;22(6):1163-1169
Separation of divinyl ether fatty acid isomers by micellar electrokinetic chromatography
Öhman M; Wang H; Hamberg M; Blomberg LG
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(9):6267-6273
Oxylipin profiling reveals the preferential stimulation of the 9-lipoxygenase pathway in elicitor-treated potato cells
Göbel C; Feussner I; Schmidt A; Scheel D; Sanchez-Serrano J; Hamberg M; Rosahl S
Article: BIOCHEMICAL JOURNAL. 2000;352(Pt 2):501-509
The lipoxygenase pathway in tulip (Tulipa gesneriana):: detection of the ketol route
Grechkin AN; Mukhtarova LS; Hamberg M
Article: LIPIDS. 2000;35(11):1205-1214
Evidence for the mitochondrial biosynthesis of 3R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid in the yeast Dipodascopsis uninucleata
Fox SR; Hamberg M; Friend J; Ratledge C
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(25):19132-19138
Molecular cloning of allene oxide cyclase - The enzyme establishing the stereochemistry of octadecanoids and jasmonates
Ziegler J; Stenzel I; Hause B; Maucher H; Hamberg M; Grimm R; Ganal M; Wasternack C
Article: LIPIDS. 2000;35(4):353-363
New cyclopentenone fatty acids formed from linoleic and linolenic acids in potato
Hamberg M
Article: FEBS LETTERS. 2000;466(1):63-66
Formation of cyclopentenones from all-(E) hydroperoxides of linoleic acid via allene oxides.: New insight into the mechanism of cyclization
Grechkin AN; Hamberg M
Article: LIPIDS. 1999;34(11):1131-1142
An epoxy alcohol synthase pathway in higher plants: Biosynthesis of antifungal trihydroxy oxylipins in leaves of potato
Hamberg M
Article: LIPIDS. 1999;34(10):1005-1015
On the specificity of allene oxide cyclase
Ziegler J; Wasternack C; Hamberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(35):24503-24513
α-oxidation of fatty acids in higher plants -: Identification of a pathogen-inducible oxygenase (PIOX) as an α-dioxygenase and biosynthesis of 2-hydroperoxylinolenic acid
Hamberg M; Sanz A; Castresana C
Article: FREE RADICAL BIOLOGY AND MEDICINE. 1999;26(1-2):129-135
Quantitative determination of 8-hydroxy-2′-deoxyguanosine in human urine by isotope dilution mass spectrometry:: Normal levels in hemochromatosis
Holmberg I; Stal P; Hamberg M
Article: ELECTROPHORESIS. 1999;20(1):132-137
Highly efficient separation of isomeric epoxy fatty acids by micellar electrokinetic chromatography
Wan H; Blomberg LG; Hamberg M
Article: LIPIDS. 1998;33(11):1061-1071
A pathway for biosynthesis of divinyl ether fatty acids in green leaves
Hamberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(21):13080-13088
Manganese lipoxygenase - Discovery of a bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction
Hamberg M; Su C; Oliw E
Article: LIPIDS. 1998;33(4):355-363
Isolation and structure of a new galactolipid from oat seeds
Hamberg M; Liepinsh E; Otting G; Griffiths W
Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 1998;349(2):376-380
Stereochemistry of oxygenation of linoleic acid catalyzed by prostaglandin-endoperoxide H synthase-2
Hamberg M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(37):23057-23063
Mutation of tyrosine 383 in leukotriene A(4) hydrolase allows conversion of leukotriene A(4) into 5S,6S-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid - Implications for the epoxide hydrolase mechanism
Andberg MB; Hamberg M; Haeggstrom JZ
Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 1997;344(1):194-199
Myoglobin-catalyzed bis-allylic hydroxylation and epoxidation of linoleic acid
Hamberg M
Article: PLANT PHYSIOLOGY. 1997;114(2):565-573
Purification and characterization of allene oxide cyclase from dry corn seeds
Ziegler J; Hamberg M; Miersch O; Parthier B
Article: THE FEBS JOURNAL. 1997;245(1):137-142
On the mechanism of biosynthesis of divinyl ether oxylipins by enzyme from garlic bulbs
Grechkin AN; Ilyasov AV; Hamberg M
Article: LIPIDS. 1996;31(10):1023-1028
Mechanism of linoleic acid hydroperoxide reaction with alkali
Gardner HW; Simpson TD; Hamberg M
Article: LIPIDS. 1996;31(8):803-809
Specificity of two lipoxygenases from rice: Unusual regiospecificity of a lipoxygenase isoenzyme
Zhang LY; Hamberg M
Article: FEBS LETTERS. 1996;388(2-3):112-114
Divinyl ether synthase from garlic (Allium sativum L) bulbs: Sub-cellular localization and substrate regio- and stereospecificity
Grechkin AN; Hamberg M
Article: THE FEBS JOURNAL. 1996;238(3):599-605
Formation of a novel enzymatic metabolite of leukotriene A(4) in tissues of Xenopus laevis
Stromberg F; Hamberg M; Rosenqvist U; Dahlen SE; Haeggstrom JZ
Article: PHYTOCHEMISTRY. 1996;42(3):729-732
15(R)-Hydroxylinoleic acid, an oxylipin from oat seeds
Hamberg M; Hamberg G
Article: PLANT PHYSIOLOGY. 1996;110(3):807-815
Peroxygenase-catalyzed fatty acid epoxidation in cereal seeds - Sequential oxidation of linoleic acid into 9(S),12(S),13(S)-trihydroxy-10(E)-octadecenoic acid
Hamberg M; Hamberg G
Article: ANALYTICAL BIOCHEMISTRY. 1995;229(2):336-344
QUANTITATIVE-DETERMINATION OF 8-HYDROXYGUANINE AND GUANINE BY ISOTOPE-DILUTION MASS-SPECTROMETRY
HAMBERG M; ZHANG LY
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1995;1257(1):58-74
ARACHIDONIC-ACID METABOLISM IN THE HUMAN MAST-CELL LINE HMC-1 - 5-LIPOXYGENASE GENE-EXPRESSION AND BIOSYNTHESIS OF THROMBOXANE
MACCHIA L; HAMBERG M; KUMLIN M; BUTTERFIELD JH; HAEGGSTROM JZ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(21):12569-12577
GROWTH-HORMONE SIGNALING LEADING TO CYP2C12 GENE-EXPRESSION IN RAT HEPATOCYTES INVOLVES PHOSPHOLIPASE A(2)
TOLLET P; HAMBERG M; GUSTAFSSON JA; MODE A
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 1995;3(1):27-38
ON THE PH-DEPENDENT DEGRADATION OF 15(S)-15-METHYL-PROSTAGLANDIN F2-ALPHA (CARBOPROST)
HAMBERG M; ZHANG LY; BERGSTROM S
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Review: FRONTIERS IN PLANT SCIENCE. 2015;6:483
Oxylipins in moss development and defense
Ponce de Leon I; Hamberg M; Castresana C
Editorial comment: CHEMISTRY AND BIOLOGY. 2013;20(2):138-140
Resolving Resolvins
Haeggstrom JZ; Hamberg M
Review: LIPIDS. 2012;47(2):101-116
Applications of Stereospecifically-Labeled Fatty Acids in Oxygenase and Desaturase Biochemistry
Brash AR; Schneider C; Hamberg M
Review: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;338(1):169-174
α-Dioxygenases
Hamberg M; de Leon IP; Rodriguez MJ; Castresana C
Published conference paper: JOURNAL OF CHROMATOGRAPHY A. 2003;985(1-2):471-478
Separation of conjugated trienoic fatty acid isomers by capillary electrophoresis
Bohlin ME; Öhman M; Hamberg M; Blomberg LG
Published conference paper: BIOCHEMICAL SOCIETY TRANSACTIONS. 2000;28(6):851-853
Lipoxygenase pathway in tulip: biosynthesis of ketols
Grechkin AN; Mukhtarova LS; Hamberg M
Published conference paper: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1999;469:319-325
Evidence for a carbocation intermediate in the enzymatic transformation of leukotriene A₄ into leukotriene B₄
Andberg M; Hamberg M; Haeggström JZ
Published conference paper: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1997;433:69-72
Avenoleic acid: A new oxylipin from oat seeds
Hamberg M
Published conference paper: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1997;433:61-64
Biosynthesis of novel divinyl ether oxylipins by enzyme from garlic (Allium sativum L.) bulbs
Grechkin AN; Hamberg M
Published conference paper: ACTA CHEMICA SCANDINAVICA. 1996;50(3):219-224
Stereochemical aspects of fatty acid oxidation: Hydroperoxide isomerases
Hamberg M
Letter: BIOORGANICHESKAYA KHIMIYA. 1996;22(12):944-945
Stereospecific synthesis of novel divinyl ether oxylipins by the enzyme from garlic bulbs
Grechkin AN; Hamberg M
Published conference paper: JOURNAL OF LIPID MEDIATORS AND CELL SIGNALLING. 1995;12(2-3):283-292
HYDROPEROXIDE ISOMERASES
HAMBERG M
Other: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(20):11761-11764
HUMAN THIOREDOXIN REDUCTASE DIRECTLY REDUCES LIPID HYDROPEROXIDES BY NADPH AND SELENOCYSTINE STRONGLY STIMULATES THE REACTION VIA CATALYTICALLY GENERATED SELENOLS
BJORNSTEDT M; HAMBERG M; KUMAR S; XUE J; HOLMGREN A
Published conference paper: ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH. 1995;23:193-198
BIOSYNTHESIS AND DEGRADATION OF ALPHA-PARANARIC ACID AND RELATED CONJUGATED TETRAENE FATTY-ACIDS
HAMBERG M
Published conference paper: ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH. 1995;23:1-9
5-LIPOXYGENASE - STRUCTURE AND STABILITY OF RECOMBINANT ENZYME, REGULATION IN MONO-MAC-6 CELLS
RADMARK O; ZHANG YY; HAMMARBERG T; LIND B; HAMBERG M; BRUNGS M; STEINHILBER D; SAMUELSSON B

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