Martin Kraepelien

Martin Kraepelien

Affiliated to Research | Docent
Visiting address: Norra Stationsgatan 69, plan 7, 11364 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 CPF, 171 77 Stockholm
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About me

  • Digital psychological interventions

Articles

All other publications

Grants

  • Swedish Research Council for Health Working Life and Welfare
    1 January 2025 - 31 December 2025
    Research idea and purposeObsessive-compulsive disorder (OCD) is a prevalent, childhood onset condition associated with substantial adversity, school failure, suicide risk, and societal costs. While reasonably effective treatments for the disorder exist, these are often offered too late, once the disorder has fully developed and has had a devastating impact on the young person’s development, education, social life and physical health. There is broad consensus in the field that we should move towards early interventions and prevention. To our knowledge, preventive approaches have never been developed for, or evaluated in, children at risk of developing OCD. The proposed project builds upon the applicant’s ongoing research on the prevention of OCD in at-risk children previously funded by a Forte postdoc grant (number 2022-00831). A feasibility study has provided encouraging preliminary results, and we are now ready to start planning a large-scale randomized controlled trial (RCT) in collaboration with prevention experts, health economists, interest organisations and stakeholders. Work plan, methods and project realizationThe overall aim is to design and prepare for the world’s first prevention trial for children at risk of developing OCD. The specific aims are to:  1) complete the follow-up assessments and analysis of qualitative data from our feasibility study, 2) find collaboration partners with expertise in prevention, statistics and health economics, 3) form a Research Steering Group together with the Swedish OCD association and persons with lived experience of OCD, and 4) plan a large scale RCT, securing recruitment sites, performing power calculations, detailed analysis plans, study protocol and ethical application. The planning grant funding is essential to ring-fence the necessary time to put together a team of experts, and carefully design a very ambitious trial which will likely involve hundreds of families across Sweden.Societal relevance and utilizationIf we can reduce the incidence of OCD and associated impairments (e.g. school failure) in these at-risk children, it would not only have obvious direct benefits for the individuals but also result in enormous cost savings on a societal level, such as healthcare costs, and parental lost work.
  • Early onset Psoriasis
    Edvard Welanders Stiftelse och Finsenstiftelsen (Hudfonden)
    30 June 2024 - 31 December 2025
  • Time to intervene - introducing a digital platform for psychological self-care for young people with psoriasis
    Stiftelsen Psoriasisfonden
    1 December 2023 - 31 December 2026
  • Time to intervene - introducing a digital platform for psychological self-care for young people with psoriasis
    Edvard Welanders Stiftelse and Finsenstiftelsen (Hudfonden)
    19 June 2023 - 31 December 2025
  • Swedish Research Council for Health Working Life and Welfare
    1 March 2023 - 28 February 2026
    Research problem and specific questionsWorldwide increases in longevity and falling fertility rates have created significant demographic transformations in society. As a consequence, the proportion of older adults (defines as &gt
    65 years) in the world is greater than ever before. We purport to develop an accessible, preventive intervention that can be delivered to older adults with early, subclinical/mild symptoms of varying forms of mental health problems. When developed, it could be easily implemented in primary care, in geriatric clinics and all other sites frequented by older adults, whether in India or Sweden.Research questions are:Is the culturally adapted digital intervention Healthy Ageing with Mental Health safe and feasible to use among older adults in Sweden and India?What is the experience of older adults in Sweden and India using the digital intervention?What preliminary effect does the digital intervention have on outcomes (e.g. quality of life, depression, anxiety, sleep problems, alcohol use, somatic health)?Data and methodWe propose to develop and systematically evaluate the digital intervention Healthy Ageing with Mental Health which aims to provide psychoeducation and prevention of common mental health problems among older adults in Sweden and India. Plan for project realisationThe intervention will be based on cognitive behavior therapy and consist of four weekly self-help modules focusing on 1) low mood 2) anxiety and somatic symptom preoccupation, 3) sleep and circadian rhythm and 4) addictive habits (including use of prescription medications). Psychoeducation about the importance of physical activity, nutrition and how these may interact with mental health problems will be an integral part of the intervention, as will information about ageism.RelevanceThe intervention developed in this project will address not one but several common mental health problems among older adults. The bilateral aspect of the project will provide further important insights into how digital interventions may be adapted to older adults in both collectivist and individualistic cultures, where one central difference is the view on older adults.
  • Swedish Research Council
    1 December 2021 - 30 November 2024
  • Swedish Research Council
    1 December 2021 - 30 November 2024
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2021 - 31 December 2022

Employments

  • Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2025-2027

Degrees and Education

  • Docent, Karolinska Institutet, 2023
  • Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2019

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