Martin Halle

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Research

Associate Professor of Plastic Surgery

Articles

Article: JOURNAL OF PLASTIC, RECONSTRUCTIVE AND AESTHETIC SURGERY. 2024;98:20-31
Donor-site safety in microvascular lymph node transfer for breast cancer-related lymphedema using reverse lymphatic mapping-A prospective study
Pajula S; Saarikko A; Suominen S; Kaartinen I; Kiiski J; Mani M; Halle M; Hartiala P
Article: NATURE COMMUNICATIONS. 2024;15(1):9286
Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors
Bian X; Piipponen M; Liu Z; Luo L; Geara J; Chen Y; Sangsuwan T; Maselli M; Diaz C; Bain CA; Eenjes E; Genander M; Crichton M; Cash JL; Archambault L; Haghdoost S; Fradette J; Sommar P; Halle M; Landen NX
Article: BJS OPEN. 2024;8(5):zrae095
Surgical complications after immediate implant-based breast reconstruction for breast cancer in women over 65 years
Liu Y; Johansson ALV; Oikonomou I; Frisell A; Adam HC; Ansarei D; Halle M; Sackey H; de Boniface J
Article: PLASTIC AND RECONSTRUCTIVE SURGERY. 2024
Phase II study shows potential benefit of adenoviral vascular endothelial growth factor C (VEGF-C) and lymph node transfer in lymphedema.
Rannikko EH; Pajula S; Suominen SH; Kiiski J; Mani MR; Halle M; Kaartinen IS; Lahdenperä O; Arnardottir TH; Kauhanen SM; Kavola H; Majava M; Niemi TS; Brück NM; Mäki MT; Seppänen MP; Saarikko AM; Hartiala P
Article: ACTA OTO-LARYNGOLOGICA. 2023;143(1):77-84
Brachytherapy and osteoradionecrosis in patients with base of tongue cancer
Danielsson D; Hagel E; Dybeck-Udd S; Sjostrom M; Kjeller G; Bengtsson M; Abtahi J; von Beckerath M; Thor A; Halle M; Friesland S; Mercke C; Westermark A; Hogmo A; Munck-Wikland E
Article: JOURNAL OF PLASTIC, RECONSTRUCTIVE AND AESTHETIC SURGERY. 2023;76:18-26
Capsular inflammation after immediate breast reconstruction-Gene expression patterns and inflammatory cell infiltration in irradiated and non-irradiated breasts
Frisell A; Bergman O; Khan A; Gistera A; Fisher RM; Lagergren J; de Boniface J; Halle M
Article: BRITISH JOURNAL OF SURGERY. 2022;109(11):1107-1115
Long-term outcomes of implant-based immediate breast reconstruction with and without radiotherapy: a population-based study
de Boniface J; Adam HC; Frisell A; Oikonomou I; Ansarei D; Konstantinidou AL; Liu Y; Alniaj BA; Wallmon P; Halle M; Johansson ALV; Sackey H
Article: PLASTIC AND RECONSTRUCTIVE SURGERY, GLOBAL OPEN. 2022;10(4):e4309
The COVID-19 Pandemic Consequences on Microsurgical Reconstructions: A Single Center's Shift of Indications
Zindrou D; Halle M; Jakobsson S
Article: ACTA OTO-LARYNGOLOGICA. 2022;142(1):78-83
Mandibular resection in patients with head and neck cancer: acute and long-term complications after reconstruction
Sjostrom M; Danielsson D; Munck-Wikland E; Nyberg J; Sandstrom K; Thor A; Johansson H; Ceghafi P; Udd SD; Emanuelsson J; Pettersson LF; Halle M; Laurell G
Article: AESTHETIC PLASTIC SURGERY. 2021;45(6):2639-2644
Considerations on the Demography of BIA-ALCL in European Countries Based on an E(A)SAPS Survey
Stark B; Magneli M; van Heijningen I; Parreira C; Bosch U; Rouif M; Halle M
Article: PLASTIC AND RECONSTRUCTIVE SURGERY, GLOBAL OPEN. 2021;9(12):e3961
Free Flap Surgery Outcome Related to Antithrombotic Treatment Regime: An Analysis of 1000 Cases
Jakobsson S; Kamali A; Nord AE; Sommar P; Halle M
Article: JOURNAL OF PLASTIC, RECONSTRUCTIVE AND AESTHETIC SURGERY. 2021;74(10):2479-2485
Increased salvage rates with early reexploration: A retrospective analysis of 547 free flap cases
Kamali A; Skogh A-CD; Nord AE; Lundgren K; Jergovic D; Nordenvall LH; Sommar P; Halle M
Article: PLASTIC AND RECONSTRUCTIVE SURGERY, GLOBAL OPEN. 2021;9(10):e3826
Beyond the 21-cm Notch-to-nipple Myth: Golden Proportions in Breast Aesthetics
Sandberg LJ; Tonseth KA; Kloster-Jensen K; Liu J; Reece G; Halle M; Edsander-Nord A; Hockerstedt A; Kauhanen S; Tindholdt TT; Gunnarsson GL; Selber JC
Article: BREAST. 2021;59:383-392
Survival in breast cancer patients with a delayed DIEP flap breast reconstruction after adjustment for socioeconomic status and comorbidity
Adam HC; Skogh ACD; Nord E; Schultz I; Gahm J; Hall P; Frisell J; Halle M; de Boniface J
Article: INJURY. 2020;51 Suppl 4:S108-S113
Evaluation and selection of lower limb lymphedema patients for lymphaticovenular anastomosis: A prospective study.
Kristiansen M; Halle M; Pignatti M; Skogh A-CD
Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;184(3):977-984
Risk factors for implant failure following revision surgery in breast cancer patients with a previous immediate implant-based breast reconstruction
Frisell A; Lagergren J; Halle M; de Boniface J
Article: PLASTIC AND RECONSTRUCTIVE SURGERY, GLOBAL OPEN. 2020;8(10):e3173
An Aesthetic Factor Priority List of the Female Breast in Scandinavian Subjects
Sandberg LJ; Tonseth KA; Kloster-Jensen K; Liu J; Robe C; Reece G; Hansen EH; Berntsen K; Halle M; Edsander-Nord A; Hockerstedt A; Kauhanen S; Sneistrup C; Tindholdt T; Petter Gullestad H; Gunnarsson GL; Berg E; Creed Selber J
Article: BJS OPEN. 2020;4(2):232-240
Influence of socioeconomic status on immediate breast reconstruction rate, patient information and involvement in surgical decision-making
Frisell A; Lagergren J; Halle M; de Boniface J
Article: CANCERS. 2020;12(3):E753-753
Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer
Drobin K; Marczyk M; Halle M; Danielsson D; Papiez A; Sangsuwan T; Bendes A; Hong M-G; Qundos U; Harms-Ringdahl M; Wersall P; Polanska J; Schwenk JM; Haghdoost S
Article: ACTA OTO-LARYNGOLOGICA. 2020;140(2):188-194
A descriptive study highlighting the differences in the treatment protocol for oral tongue cancer in Sweden and Finland
Makitie A; Kamali A; Mroueh R; Lindford A; Koivunen P; Autio T; Lassus P; Halle M; Back L; Palmgren B; Hammarstedt-Nordenvall L
Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;179(3):721-729
Socioeconomic status differs between breast cancer patients treated with mastectomy and breast conservation, and affects patient-reported preoperative information
Frisell A; Lagergren J; Halle M; de Boniface J
Article: INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY. 2020;49(1):1-6
Osteoradionecrosis, an increasing indication for microvascular head and neck reconstruction
Danielsson D; Gahm C; Haghdoost S; Munck-Wikland E; Halle M
Article: EUROPEAN HEART JOURNAL. 2019;40(30):2495-2503
Prevention of radiotherapy-induced arterial inflammation by interleukin-1 blockade
Christersdottir T; Pirault J; Gistera A; Bergman O; Gallina AL; Baumgartner R; Lundberg AM; Eriksson P; Yan Z-Q; Paulsson-Berne G; Hansson GK; Olofsson PS; Halle M
Article: HEAD AND NECK. 2019;41(7):2225-2230
Quality of life after microvascular mandibular reconstruction for osteoradionecrosis-A prospective study
Danielsson D; Munck-Wikland E; Hagel E; Halle M
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2019;4(1):72-82
miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease
Eken SM; Christersdottir T; Winski G; Sangsuwan T; Jin H; Chernogubova E; Pirault J; Sun C; Simon N; Winter H; Backlund A; Haghdoost S; Hansson GK; Halle M; Maegdefessel L
Article: MEDIATORS OF INFLAMMATION. 2018;2018:4058986-9
Upregulation of Plasminogen Activator Inhibitor-1 in Irradiated Recipient Arteries and Veins from Free Tissue Transfer Reconstruction in Cancer Patients
Eriksson BO; Gahm C; Halle M
Article: SCIENCE TRANSLATIONAL MEDICINE. 2018;10(425):eaar2041
Genetically modified lentiviruses that preserve microvascular function protect against late radiation damage in normal tissues
Khan AA; Paget JT; McLaughlin M; Kyula JN; Wilkinson MJ; Pencavel T; Mansfield D; Roulstone V; Seth R; Halle M; Somaiah N; Boult JKR; Robinson SP; Pandha HS; Vile RG; Melcher AA; Harris PA; Harrington KJ
Article: ACTA OTO-LARYNGOLOGICA. 2017;137(7):755-761
Regional recurrence in early stage I-II oral tongue cancer: a single institutional study and review of the literature
Kamali A; Gahm C; Palmgren B; Marklund L; Halle M; Hammarstedt-Nordenvall L
Article: PLASTIC AND RECONSTRUCTIVE SURGERY, GLOBAL OPEN. 2017;5(3):e1253
Improved Head and Neck Free Flap Outcome-Effects of a Treatment Protocol Adjustment from Pre- to Postoperative Radiotherapy.
Halle M; Eriksson BO; Docherty Skogh A-C; Sommar P; Hammarstedt L; Gahm C
Article: THE FASEB JOURNAL. 2016;30(11):3845-3852
Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors
Halle M; Christersdottir T; Back M
Article: JOURNAL OF PLASTIC SURGERY AND HAND SURGERY. 2016;50(4):197-201
Breast free flap complications related to haematoma formation - do the risks of multiple antithrombotics outweigh the benefits today?
Halle M; Skogh A-CD; Friberg A; Edsander-Nord A
Article: HEAD AND NECK. 2016;38(3):387-393
Influence of genetic background and oxidative stress response on risk of mandibular osteoradionecrosis after radiotherapy of head and neck cancer
Danielsson D; Brehwens K; Halle M; Marczyk M; Sollazzo A; Polanska J; Munck-Wikland E; Wojcik A; Haghdoost S
Article: JOURNAL OF PLASTIC, RECONSTRUCTIVE AND AESTHETIC SURGERY. 2016;69(2):255-261
Composite orbital reconstruction using the vascularized segmentalized osteo-fascio-cutaneous fibula flap
Lundgren TK; Pignatti M; Halle M; Boscaini G; Skogh A-CD; Luigi C; De Santis G
Article: ANNALS OF PLASTIC SURGERY. 2015;75(3):309-315
Vascular Complications After Radiotherapy in Head and Neck Free Flap Reconstruction Clinical Outcome Related to Vascular Biology
Tall J; Bjorklund TC; Skogh A-CD; Arnander C; Halle M
Article: JOURNAL OF TRAUMA MANAGEMENT AND OUTCOMES. 2015;9:3
Effects of a formalized collaboration between plastic and orthopedic surgeons in severe extremity trauma patients; a retrospective study.
Sommar P; Granberg Y; Halle M; Skogh A-CD; Lundgren KT; Jansson K-Å
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2013;11:223
Increased long-term expression of pentraxin 3 in irradiated human arteries and veins compared to internal controls from free tissue transfers
Bjorklund TC; Reilly S-J; Gahm C; Bottazzi B; Mantovani A; Tornvall P; Halle M
Article: JOURNAL OF PLASTIC, RECONSTRUCTIVE AND AESTHETIC SURGERY. 2010;63(11):1910-1916
Endothelial activation with prothrombotic response in irradiated microvascular recipient veins
Halle M; Ekstrom M; Farnebo F; Tornvall P
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2010;299(2):E234-E240
Systemic inflammation activates the nuclear factor-κB regulatory pathway in adipose tissue
Ekstrom M; Halle M; Bjessmo S; Liska J; Kolak M; Fisher R; Eriksson P; Tornvall P
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2010;55(12):1227-1236
Sustained Inflammation Due to Nuclear Factor-Kappa B Activation in Irradiated Human Arteries
Halle M; Gabrielsen A; Paulsson-Berne G; Gahm C; Agardh HE; Farnebo F; Tornvall P
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All other publications

Published conference paper: BRITISH JOURNAL OF SURGERY. 2019;106(5):563-573
Autologous fat transplantation alters gene expression patterns related to inflammation and hypoxia in the irradiated human breast
Lindegren A; Schultz I; Sinha I; Cheung L; Khan AA; Tekle M; Wickman M; Halle M
Published conference paper: BRITISH JOURNAL OF SURGERY. 2018;105(11):1435-1445
Risk of recurrence and death in patients with breast cancer after delayed deep inferior epigastric perforator flap reconstruction
Adam H; Skogh ACD; Nord AE; Schultz I; Gahm J; Hall P; Frisell J; Halle M; de Boniface J
Published conference paper: PLASTIC AND RECONSTRUCTIVE SURGERY. 2012;130(1):10-18
Postmastectomy Breast Reconstruction in the Irradiated Breast: A Comparative Study of DIEP and Latissimus Dorsi Flap Outcome
Lindegren A; Halle M; Skogh A-CD; Edsander-Nord A
Letter: PLASTIC AND RECONSTRUCTIVE SURGERY. 2012;129(3):549e-550e
Does Previous Head and Neck Irradiation Increase Vascular Complications in Free Autologous Reconstruction?
Halle M; Farnebo F
Letter: JOURNAL OF INTERNAL MEDICINE. 2011;270(5):486
Beyond nuclear factor kappaB in cardiovascular disease induced by radiotherapy
Halle M; Tornvall P
Review: JOURNAL OF INTERNAL MEDICINE. 2011;269(5):469-477
Cardiovascular disease associated with radiotherapy: activation of nuclear factor kappa-B
Halle M; Hall P; Tornvall P
Thesis / dissertation: 2010
Vascular inflammation : implications for microvascular reconstructive surgery after irradiation
Halle, Martin
Published conference paper: JOURNAL OF PLASTIC, RECONSTRUCTIVE AND AESTHETIC SURGERY. 2009;62(7):889-895
Timing of radiotherapy in head and neck free flap reconstruction - a study of postoperative complications
Halle M; Bodin I; Tornvall P; Wickman M; Farnebo F; Arnander C
Letter: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2005;35(2):154-155
Effects of free fatty acids and a triglyceride-rich fat emulsion on endothelial nitric oxide synthase
Halle M; Eriksson P; Tornvall P

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2027

Degrees and Education

Docent, Karolinska Institutet, 2020
Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2010
University Medical Degree, Karolinska Institutet, 2001

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