Maria Issagouliantis

Publications
CV
Public outreach and news

Articles

Article: CANCERS. 2024;16(4):818

Chronic Viral Infections and Cancer, Openings for Therapies and Vaccines

Isaguliants MG; Ivanov AV; Buonaguro FM
Article: VIRUSES-BASEL. 2024;16(2):193

HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype

Zhitkevich A; Bayurova E; Avdoshina D; Zakirova N; Frolova G; Chowdhury S; Ivanov A; Gordeychuk I; Palefsky JM; Isaguliants M
Article: MICROORGANISMS. 2023;11(4):1004

Is There a Future for Traditional Immunogens When We Have mRNA?

Kyuregyan KK; Jansons J; Isaguliants M
Article: CANCERS. 2023;15(3):660

HPV Type Distribution in Benign, High-Grade Squamous Intraepithelial Lesions and Squamous Cell Cancers of the Anus by HIV Status

Chowdhury S; Darragh TMM; Berry-Lawhorn JM; Isaguliants MGG; Vonsky MSS; Hilton JFF; Lazar AAA; Palefsky JMM
Article: CANCERS. 2022;15(1):238

HIV-1 Protease as DNA Immunogen against Drug Resistance in HIV-1 Infection: DNA Immunization with Drug Resistant HIV-1 Protease Protects Mice from Challenge with Protease-Expressing Cells

Petkov S; Kilpelaeinen A; Bayurova E; Latanova A; Mezale D; Fridrihsone I; Starodubova E; Jansons J; Dudorova A; Gordeychuk I; Wahren B; Isaguliants M
Article: MOLECULAR BIOLOGY. 2022;56(5):795-807

[Expression of HIV-1 Reverse Transcriptase in Murine Cancer Cells Increases Mitochondrial Respiration].

Zakirova NF; Kondrashova AS; Golikov MV; Ivanova ON; Ivanov AV; Isaguliants MG; Bayurova EO
Article: INFECTIOUS AGENTS AND CANCER. 2022;17(SUPPL 2):28

An overview of "Chronic viral infection and cancer, openings for vaccines" virtual symposium of the TechVac Network - December 16-17, 2021

Isaguliants MG; Trotsenko I; Buonaguro FM
Article: VACCINE. 2022;40(1):89-99

Immunization with recombinant ORF2 p551 protein protects common marmosets (Callithrix jacchus) against homologous and heterologous hepatitis E virus challenge

Gordeychuk I; Kyuregyan K; Kondrashova A; Bayurova E; Gulyaev S; Gulyaeva T; Potemkin I; Karlsen A; Isaeva O; Belyakova A; Lyashenko A; Sorokin A; Chumakov A; Morozov I; Isaguliants M; Ishmukhametov A; Mikhailov M
Article: VACCINES. 2021;9(11):1247

Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model

Trofimova O; Korotkaja K; Skrastina D; Jansons J; Spunde K; Isaguliants M; Zajakina A
Article: BIOMEDICINES. 2021;9(6):683

Prevalence and Risk Factors of Infection with High Risk Human Papilloma Viruses among HIV-Positive Women with Clinical Manifestations of Tuberculosis in a Middle-Income Country

Isaguliants M; Nosik M; Karlsen A; Petrakova N; Enaeva M; Lebedeva N; Podchufarova D; Laga V; Gromov K; Nazarov A; Chowdhury S; Sinitsyn M; Sobkin A; Chistyakova N; Aleshina S; Grabarnik A; Palefsky JM
Article: MICROORGANISMS. 2021;9(6):1219

Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells

Isaguliants M; Krotova O; Petkov S; Jansons J; Bayurova E; Mezale D; Fridrihsone I; Kilpelainen A; Podschwadt P; Agapkina Y; Smirnova O; Kostic L; Saleem M; Latyshev O; Eliseeva O; Malkova A; Gorodnicheva T; Wahren B; Gordeychuk I; Starodubova E; Latanova A
Article: MICROORGANISMS. 2021;9(5):1073

Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer

Jansons J; Skrastina D; Kurlanda A; Petkov S; Avdoshina D; Kuzmenko Y; Krotova O; Trofimova O; Gordeychuk I; Sominskaya I; Isaguliants M
Article: VACCINES. 2021;9(2):82

Coverage with Timely Administered Vaccination against Hepatitis B Virus and Its Influence on the Prevalence of HBV Infection in the Regions of Different Endemicity

Kyuregyan KK; Kichatova VS; Isaeva OV; Potemkin IA; Malinnikova EY; Lopatukhina MA; Karlsen AA; Mobarhan FAA; Mullin EV; Slukinova OS; Ignateva ME; Sleptsova SS; Oglezneva EE; Shibrik EV; Isaguliants MG; Mikhailov MI
Article: VACCINES. 2020;8(2):E318-318

Expression of the Reverse Transcriptase Domain of Telomerase Reverse Transcriptase Induces Lytic Cellular Response in DNA-Immunized Mice and Limits Tumorigenic and Metastatic Potential of Murine Adenocarcinoma 4T1 Cells

Jansons J; Bayurova E; Skrastina D; Kurlanda A; Fridrihsone I; Kostyushev D; Kostyusheva A; Artyuhov A; Dashinimaev E; Avdoshina D; Kondrashova A; Valuev-Elliston V; Latyshev O; Eliseeva O; Petkov S; Abakumov M; Hippe L; Kholodnyuk I; Starodubova E; Gorodnicheva T; Ivanov A; Gordeychuk I; Isaguliants M
Article: BIOMEDICINES. 2020;8(4):E80-80

Factors Influencing the Prevalence of Resistance-Associated Substitutions in NS5A Protein in Treatment-Naive Patients with Chronic Hepatitis C

Kyuregyan KK; Kichatova VS; Karlsen AA; Isaeva OV; Solonin SA; Petkov S; Nielsen M; Isaguliants MG; Mikhailov MI
Article: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2020;2020:5829521-4

Redox Biology of Infection and Consequent Disease

Isaguliants MG; Bartosch B; Ivanov AV
Article: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019;2019:6016278-28

HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist

Bayurova E; Jansons J; Skrastina D; Smirnova O; Mezale D; Kostyusheva A; Kostyushev D; Petkov S; Podschwadt P; Valuev-Elliston V; Sasinovich S; Korolev S; Warholm P; Latanova A; Starodubova E; Tukhvatulin A; Latyshev O; Selimov R; Metalnikov P; Komarov A; Ivanova O; Gorodnicheva T; Kochetkov S; Gottikh M; Strumfa I; Ivanov A; Gordeychuk I; Isaguliants MG
Article: MICROORGANISMS. 2019;7(11):E533-533

Replenishment of Hepatitis B Virus cccDNA Pool Is Restricted by Baseline Expression of Host Restriction Factors In Vitro

Brezgin S; Kostyusheva A; Bayurova E; Gordeychuk I; Isaguliants M; Goptar I; Nikiforova A; Smirnov V; Volchkova E; Glebe D; Kostyushev D; Chulanov V
Article: VIRUSES-BASEL. 2019;11(11):E997-997

ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage

Kostyusheva A; Brezgin S; Bayurova E; Gordeychuk I; Isaguliants M; Goptar I; Urusov F; Nikiforova A; Volchkova E; Kostyushev D; Chulanov V
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;513(3):535-539

Evaluation of cyclic luciferin as a substrate for luminescence measurements in in vitro and in vivo applications

Abakumov M; Kilpelainen A; Petkov S; Belikov S; Klyachko N; Chekhonin V; Isaguliants M
Article: CELLS. 2019;8(3):E208-208

The Immunogenicity in Mice of HCV Core Delivered as DNA Is Modulated by Its Capacity to Induce Oxidative Stress and Oxidative Stress Response

Jansons J; Sominskaya I; Petrakova N; Starodubova ES; Smirnova OA; Alekseeva E; Bruvere R; Eliseeva O; Skrastina D; Kashuba E; Mihailova M; Kochetkov SN; Ivanov AV; Isaguliants MG
Article: JOURNAL OF VIROLOGICAL METHODS. 2018;262:12-19

A qPCR assay for measuring the post-integrational DNA repair in HIV-1 replication

Anisenko AN; Knyazhanskaya ES; Isaguliants MG; Gottikh MB
Article: ACTA NATURAE. 2018;10(4):63-69

Assessment of the Parameters of Adaptive Cell-Mediated Immunity in Naive Common Marmosets (Callithrix jacchus)

Gordeychuk IV; Tukhvatulin AI; Petkov SP; Abakumov MA; Gulyaev SA; Tukhvatulina NM; Gulyaeva TV; Mikhaylov MI; Logunov DY; Isaguliants MG
Article: SCIENTIFIC REPORTS. 2018;8(1):8078

Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity

Latanova AA; Petkov S; Kilpelainen A; Jansons J; Latyshev OE; Kuzmenko YV; Hinkula J; Abakumov MA; Valuev-Elliston VT; Gomelsky M; Karpov VL; Chiodi F; Wahren B; Logunov DY; Starodubova ES; Isaguliants MG
Article: PLOS ONE. 2018;13(6):e0197902

DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response

Petkov S; Starodubova E; Latanova A; Kilpelainen A; Latyshev O; Svirskis S; Wahren B; Chiodi F; Gordeychuk I; Isaguliants M
Article: SCIENTIFIC REPORTS. 2017;7(1):7715

Luciferase Expression Allows Bioluminescence Imaging But Imposes Limitations on the Orthotopic Mouse (4T1) Model of Breast Cancer

Baklaushev VP; Kilpelainen A; Petkov S; Abakumov MA; Grinenko NF; Yusubalieva GM; Latanova AA; Gubskiy IL; Zabozlaev FG; Starodubova ES; Abakumova TO; Isaguliants MG; Chekhonin VP
Article: GENES & DEVELOPMENT. 2017;31(12):1212-1227

Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity

Zanca C; Villa GR; Benitez JA; Thorne AH; Koga T; D'Antonio M; Ikegami S; Ma J; Boyer AD; Banisadr A; Jameson NM; Parisian AD; Eliseeva OV; Barnabe GF; Liu F; Wu S; Yang H; Wykosky J; Frazer KA; Verkhusha VV; Isaguliants MG; Weiss WA; Gahman TC; Shiau AK; Chen CC; Mischel PS; Cavenee WK; Furnari FB
Article: HELIYON. 2017;3(6):e00339

HIVIS-DNA or HIVISopt-DNA priming followed by CMDR vaccinia-based boosts induce both humoral and cellular murine immune responses to HIV.

Hinkula J; Petkov S; Ljungberg K; Hallengärd D; Bråve A; Isaguliants M; Falkeborn T; Sharma S; Liakina V; Robb M; Eller M; Moss B; Biberfeld G; Sandström E; Nilsson C; Markland K; Blomberg P; Wahren B
Article: ONCOTARGET. 2017;8(3):3895-3932

Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis

Ivanov AV; Valuev-Elliston VT; Tyurina DA; Ivanova ON; Kochetkov SN; Bartosch B; Isaguliants MG
Article: JOURNAL OF IMMUNOLOGY RESEARCH. 2017;2017:7407136-16

Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice

Latanova A; Petkov S; Kuzmenko Y; Kilpelainen A; Ivanov A; Smirnova O; Krotova O; Korolev S; Hinkula J; Karpov V; Isaguliants M; Starodubova E
Article: VIRUSES-BASEL. 2015;7(6):2745-2770

HCV Core Protein Uses Multiple Mechanisms to Induce Oxidative Stress in Human Hepatoma Huh7 Cells

Ivanov AV; Smirnova OA; Petrushanko IY; Ivanova ON; Karpenko IL; Alekseeva E; Sominskaya I; Makarov AA; Bartosch B; Kochetkov SN; Isaguliants MG
Article: ACTA NATURAE. 2015;7(1):78-86

Influence of Drug Resistance Mutations on the Activity of HIV-1 Subtypes A and B Integrases: a Comparative Study

Shadrina OA; Zatsepin TS; Agapkina YY; Isaguliants MG; Gottikh MB
Article: JOURNAL OF IMMUNOLOGY RESEARCH. 2015;2015:762426-12

Comparative Immunogenicity in Rabbits of the Polypeptides Encoded by the 5′ Terminus of Hepatitis C Virus RNA

Sominskaya I; Jansons J; Dovbenko A; Petrakova N; Lieknina I; Mihailova M; Latyshev O; Eliseeva O; Stahovska I; Akopjana I; Petrovskis I; Isaguliants M
Article: BIOCHIMIE. 2014;102:92-101

Consensus HIV-1 subtype A integrase and its raltegravir-resistant variants: Design and characterization of the enzymatic properties

Shadrina O; Krotova O; Agapkina J; Knyazhanskaya E; Korolev S; Starodubova E; Viklund A; Lukashov V; Magnani M; Medstrand P; Karpov V; Gottikh M; Isaguliants M
Article: ACTA NATURAE. 2014;6(1):61-68

Fusion to the Lysosome Targeting Signal of the Invariant Chain Alters the Processing and Enhances the Immunogenicity of HIV-1 Reverse Transcriptase

Starodubova ES; Isaguliants MG; Kuzmenko YV; Latanova AA; Krotova OA; Karpov VL
Article: HUMAN VACCINES & IMMUNOTHERAPEUTICS. 2013;9(10):2228-2236

Evaluation of immunogen delivery by DNA immunization using non-invasive bioluminescence imaging

Petkov SP; Heuts F; Krotova OA; Kilpelainen A; Engstrom G; Starodubova ES; Isaguliants MG
Article: HUMAN VACCINES & IMMUNOTHERAPEUTICS. 2013;9(10):2111-2119

Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzyme's performance in gene immunization

Isaguliants M; Smirnova O; Ivanov AV; Kilpelainen A; Kuzmenko Y; Petkov S; Latanova A; Krotova O; Engstroem G; Karpov V; Kochetkov S; Wahren B; Starodubova E
Article: PLOS ONE. 2013;8(5):e62720

Consensus HIV-1 FSU-A Integrase Gene Variants Electroporated into Mice Induce Polyfunctional Antigen-Specific CD4+and CD8+T Cells

Krotova O; Starodubova E; Petkov S; Kostic L; Agapkina J; Hallengard D; Viklund A; Latyshev O; Gelius E; Dillenbeck T; Karpov V; Gottikh M; Belyakov IM; Lukashov V; Isaguliants MG
Article: MOLECULAR IMAGING. 2012;11(6):471-486

Cellular Immunogenicity of Novel Gene Immunogens in Mice Monitored by In Vivo Imaging

Starodubova E; Krotova O; Hallengard D; Kuzmenko Y; Engstrom G; Legzdina D; Latyshev O; Eliseeva O; Maltais AK; Tunitskaya V; Karpov V; Brave A; Isaguliants M
Article: BIOCHIMIE. 2012;94(9):1876-1883

Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N¹-acetyltransferase in human hepatoma HUH7 cells

Smirnova OA; Isaguliants MG; Hyvonen MT; Keinanen TA; Tunitskaya VL; Vepsalainen J; Alhonen L; Kochetkov SN; Ivanov AV
Article: GENETIC VACCINES AND THERAPY. 2012;10(1):5

A combination of intradermal jet-injection and electroporation overcomes in vivo dose restriction of DNA vaccines.

Hallengärd D; Bråve A; Isaguliants M; Blomberg P; Enger J; Stout R; King A; Wahren B
Article: VIROLOGY JOURNAL. 2012;9:76

Hepatitis C virus-specific cellular immune responses in individuals with no evidence of infection

Riviere Y; Montange T; Janvier G; Marnata C; Durrieu L; Chaix M-L; Isaguliants M; Launay O; Bresson J-L; Pol S
Article: VACCINE. 2011;29(4):839-848

Increased expression and immunogenicity of HIV-1 protease following inactivation of the enzymatic activity

Hallengard D; Haller BK; Petersson S; Boberg A; Maltais A-K; Isaguliants M; Wahren B; Brave A
Article: PLOS ONE. 2011;6(9):e24957

Hepatitis C Virus Proteins Activate NRF2/ARE Pathway by Distinct ROS-Dependent and Independent Mechanisms in HUH7 Cells

Ivanov AV; Smirnova OA; Ivanova ON; Masalova OV; Kochetkov SN; Isaguliants MG
Article: VACCINE. 2010;28(8):1987-1996

The successful immune response against hepatitis C nonstructural protein 5A (NS5A) requires heterologous DNA/protein immunization

Masalova OV; Lesnova EI; Pichugin AV; Melnikova TM; Grabovetsky VV; Petrakova NV; Smirnova OA; Ivanov AV; Zaberezhny AD; Ataullakhanov RI; Isaguliants MG; Kushch AA
Article: VACCINE. 2010;28(8):1975-1986

Potent cross-reactive immune response against the wild-type and drug-resistant forms of HIV reverse transcriptase after the chimeric gene immunization

Starodubova E; Boberg A; Ivanov A; Latyshev O; Petrakova N; Kuzmenko Y; Litvina M; Chernousov A; Kochetkov S; Karpov V; Wahren B; Isaguliants MG
Article: GENETIC VACCINES AND THERAPY. 2009;7:7

Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen.

Alekseeva E; Sominskaya I; Skrastina D; Egorova I; Starodubova E; Kushners E; Mihailova M; Petrakova N; Bruvere R; Kozlovskaya T; Isaguliants M; Pumpens P
Article: MOLECULAR IMMUNOLOGY. 2009;46(7):1467-1480

Autoimmunogenicity of the helix-loop-helix DNA-binding domain

Petrakova N; Gudmundsdotter L; Yermalovich M; Belikov S; Eriksson L; Pyakurel P; Johansson O; Biberfeld P; Andersson S; Isaguliants M
Article: EKSPERIMENTAL'NAIA I KLINICHESKAIA GASTROENTEROLOGIIA = EXPERIMENTAL & CLINICAL GASTROENTEROLOGY. 2009;(8):12-18

[Acute hepatitis of unspecified etiology: etiological structure and clinical-laboratory characteristics].

Iushchuk ND; Tsyganova EV; Znoĭko OO; Karetkina GN; Solonin SA; Mikhaĭlov MI; Isaguliants MG; Petrova TV; Kashirin VI; Cheshik DS
Article: VACCINE. 2008;26(40):5170-5176

HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response

Starodubova ES; Boberg A; Litvina M; Morozov A; Petrakova NV; Timofeev A; Latyshev O; Tunitskaya V; Wahren B; Isaguliants MG; Karpov VL
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(14):5489-5494

EBV-encoded EBNA-6 binds and targets MRS18-2 to the nucleus, resulting in the disruption of pRb-E2F1 complexes

Kashuba E; Yurchenko M; Yenamandra SP; Snopok B; Isaguliants M; Szekely L; Klein G
Article: MOLECULAR BIOLOGY. 2006;40(6):885-890

Artificial acceleration of HIV-1 reverse transcriptase turnover via the proteasome pathway

Starodubova ES; Isaguliants MG; Karpov VL
Article: MOLECULAR BIOLOGY. 2006;40(6):982-988

[Artifitial increase of HIV-1 reverse transcriptase turnover through proteasome pathway].

Starodubova ES; Isaguliants MG; Karpov VL
Article: CELL BIOLOGY INTERNATIONAL. 2006;30(11):915-919

Different transformation pathways of murine fibroblast NIH 3T3 cells by hepatitis C virus core and NS3 proteins

Smirnova IS; Aksenov ND; Vonsky MS; Isaguliants MG
Article: VACCINE. 2006;24(21):4541-4547

HIV-1 reverse transcriptase targeted for proteasomal degradation as a prototype vaccine against drug-resistant HIV-1

Starodubova E; Boberg A; Kashuba EV; Wahren B; Karpov V; Isaguliants M
Article: MOLECULAR IMMUNOLOGY. 2006;43(12):1941-1952

Signal sequences modulate the immunogenic performance of human hepatitis C virus E2 gene

Sominskaya I; Alekseeva E; Skrastina D; Mokhonov V; Starodubova E; Jansons J; Levi M; Prilipov A; Kozlovska T; Smirnov V; Pumpens P; Isaguliants MG
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(2):1215-1223

Regulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 protein

Kashuba EV; Gradin K; Isaguliants M; Szekely L; Poellinger L; Klein G; Kazlauskas A
Article: CELLULAR ONCOLOGY. 2006;28(4):177-190

Hepatitis C virus core protein transforms murine fibroblasts by promoting genomic instability

Smirnova IS; Aksenov ND; Kashuba EV; Payakurel P; Grabovetsky VV; Zaberezhny AD; Vonsky MS; Buchinska L; Biberfeld P; Hinkula J; Isaguliants MG
Article: MOLECULAR THERAPY. 2005;12(6):1197-1205

Multigene/multisubtype HIV-1 vaccine induces potent cellular and humoral immune responses by needle-free intradermal delivery

Bråve A; Ljungberg K; Boberg A; Rollman E; Isaguliants M; Lundgren B; Blomberg P; Hinkula J; Wahren B
Article: MICROBES AND INFECTION. 2005;7(14):1414-1423

The rationale behind a vaccine based on multiple HIV antigens

Rollman E; Bråve A; Boberg A; Gudmundsdotter L; Engström G; Isaguliants A; Ljungberg K; Lundgren B; Blomberg P; Hinkula J; Hejdeman B; Sandström E; Liu M; Wahren B
Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2005;23(2):193-202

Sequence-specific minor groove binding ligands as potential regulators of gene expression in Xenopus laevis Oocytes

Belikov SV; Grokhovsky SL; Isaguliants MG; Surovaya AN; Gursky GV
Article: TERAPEVTICHESKII ARKHIV. 2005;77(11):32-37

Immune status of patients with different outcomes of acute hepatitis C

Yuschuk ND; Dudina K; Znoiko OO; Malkov IG; Kuzina LE; Cheshik DS; Isagulyants MG
Article: VACCINE. 2004;22(13-14):1810-1819

Reverse transcriptase-based DNA vaccines against drug-resistant HIV-1 tested in a mouse model

Isaguliants MG; Zuber B; Boberg A; Sjöstrand D; Belikov SV; Rollman E; Zuber AK; Rechinsky VO; Rytting AS; Källander CFR; Hinkula J; Kochetkov SN; Liu M; Wahren R
Article: VACCINE. 2004;22(13-14):1791-1798

Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA

Zuber AK; Bråve A; Engström G; Zuber B; Ljungberg K; Fredriksson M; Benthin R; Isaguliants MG; Sandström E; Hinkula J; Wahren B
Article: VACCINE. 2004;22(13-14):1656-1665

Immunization with hepatitis C virus core gene triggers potent T-cell response, but affects CD4+T-cells

Isaguliants MG; Petrakova NV; Kashuba EV; Suzdaltzeva YG; Belikov SV; Mokhonov VV; Prilipov AG; Matskova L; Smirnova IS; Jolivet-Reynaud C; Nordenfeldt E
Article: VACCINE. 2004;22(11-12):1576-1585

Gene immunization may induce secondary antibodies reacting with DNA

Isaguliants MG; Iakimtchouk K; Petrakova NV; Yermalovich MA; Zuber AK; Kashuba VI; Belikov SV; Andersson S; Kochetkov SN; Klinman DM; Wahren B
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2004;20(2):191-201

Mutations conferring drug resistance affect eukaryotic expression of HIV type 1 reverse transcriptase

Isaguliants MG; Belikov SV; Starodubova ES; Gizatullin RZ; Rollman E; Zuber B; Zuber AK; Andreeva OI; Rytting AS; Källander CFR; Kochetkov SN; Karpov VL; Wahren B
Article: IMMUNOLOGY LETTERS. 2003;88(1):1-13

DNA immunization efficiently targets conserved functional domains of protease and ATPase/helicase of nonstructural 3 protein (NS3) of human hepatitis C virus

Isaguliants MG; Petrakova NV; Mokhonov VV; Pokrovskaya K; Suzdaltzeva YG; Krivonos AV; Zaberezhny AD; Garaev MM; Smirnov VD; Nordenfelt E
Article: JOURNAL OF MEDICAL VIROLOGY. 2002;66(2):204-217

Antibody responses against B-cell epitopes of the hypervariable region 1 of hepatitis C virus in self-limiting and chronic human hepatitis C followed-up using consensus peptides

Isaguliants MG; Widell A; Zhang SMM; Sidorchuk A; Levi M; Smirnov VD; Santantonio T; Diepolder HM; Pape GR; Nordenfelt E
Article: AIDS RESEARCH AND HUMAN RETROVIRUSES. 2000;16(13):1269-1280

Immunogenic properties of reverse transcriptase of HIV type 1 assessed by DNA and protein immunization of rabbits

Isaguliants MG; Gudima SO; Ivanova OV; Levi M; Hinkula J; Garaev MM; Kochetkov SN; Wahren B
Article: INTERVIROLOGY. 2000;43(4-6):288-293

DNA-encoding enzymatically active HIV-1 reverse transcriptase, but not the inactive mutant, confers resistance to experimental HIV-1 challenge

Isaguliants MG; Petrakova N; Zuber B; Pokrovskaya K; Gizatullin R; Kostyuk DA; Kjerrström A; Winberg G; Kochetkov SN; Hinkula J; Wahren B
Article: FEBS LETTERS. 1999;447(2-3):232-236

Eukaryotic expression of enzymatically active human immunodeficiency virus type 1 reverse transcriptase

Isaguliants MG; Pokrovskaya K; Kashuba VI; Pokholok D; Hinkula J; Wahren B; Kochetkov SN
Article: BIOCHEMISTRY-MOSCOW. 1998;63(5):551-558

Specificity of humoral and cellular immune response against recombinant particles of nucleocapsid protein of human hepatitis B virus in rabbits

Isaguliants MG; Kadoshnikov YP; Kalinina TI; Smirnov VD; Wahren B
Article: ARCHIVES OF MEDICAL RESEARCH. 1997;28 Spec No:314-316

Amebiasis in León, Nicaragua: Entamoebae in stool examination and identification of amebic liver abscess cases by serology and PCR.

Linder E; Isaguliants M; Olsson M; Lundin L; Zindrou S; Corrales E; Tellez A; Leiva B; Morales W; Rivera T; Cabrera JM
Article: IMMUNOLOGY LETTERS. 1996;52(1):37-44

HIV-1 epitopes exposed by hybrid hepatitis B core particles affect proliferation of peripheral blood mononuclear cells from HIV-1 positive donors

Isaguliants MG; Nordlund S; Sallberg M; Smirnov VD; Ruden U; Wahren B
Article: BIOCHEMISTRY-MOSCOW. 1996;61(7):1221-1229

[Composition of HIV-1 B-epitopes and heterologous T-cell epitopes. I. Maintenance of antigenic properties of HIV-1 B-epitopes].

Isaguliants MG; Koshida R; Ruden U; Varen B
Article: BIOCHEMISTRY-MOSCOW. 1996;61(3):532-545

[Expression of HIV-1 epitopes included in particles formed by human hepatitis B virus nucleocapsid protein].

Isaguliants MG; Kadoshnikov IP; Kalinina TI; Khuliakov IE; Semiletov IA; Smirnov VD; Wahren B
Article: BIOCHEMISTRY-MOSCOW. 1996;61(7):878-885

Linear fusion of HIV-1 B-epitopes and heterologous T-Cell epitopes .2. Multiparametric assay of immunogenicity of composite peptides in rabbits

Isaguliants MG; Ruden U; Wahren B
Article: BIOCHEMISTRY-MOSCOW. 1996;61(3):393-403

Expression of HIV-1 epitopes inserted into the nucleocapsid protein of human hepatitis B virus

Isaguliants MG; Kadoshnikov YP; Kalinina TI; Khudyakov YE; Semiletov YA; Smirnov VD; Wahren B
Article: BIOCHEMISTRY-MOSCOW. 1996;61(7):872-877

Linear fusion of HIV-1 B-epitopes and heterologous T-cell epitopes .1. Preservation of the antigenic properties of the HIV-1 B-cell epitopes

Isaguliants MG; Koshida R; Ruden U; Wahren B
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Corrigendum: VIRUSES-BASEL. 2024;16(4):589

HIV-1 Reverse Transcriptase Expression in HPV16-Infected Epidermoid Carcinoma Cells Alters E6 Expression and Cellular Metabolism, and Induces a Hybrid Epithelial/Mesenchymal Cell Phenotype. (vol 16, 193, 2024)

Zhitkevich A; Bayurova E; Avdoshina D; Zakirova N; Frolova G; Chowdhury S; Ivanov A; Gordeychuk I; Palefsky JM; Isaguliants M
Editorial comment: VACCINES. 2022;10(6):891

Perspective Technologies of Vaccination: Do We Still Need Old Vaccines?

Isaguliants M; Burt FJ
Review: INFECTIOUS AGENTS AND CANCER. 2021;16(1):29

Genetic instability and anti-HPV immune response as drivers of infertility associated with HPV infection

Isaguliants M; Krasnyak S; Smirnova O; Colonna V; Apolikhin O; Buonaguro FM
Review: CANCERS. 2021;13(2):305

Oncogenic Effects of HIV-1 Proteins, Mechanisms Behind

Isaguliants M; Bayurova E; Avdoshina D; Kondrashova A; Chiodi F; Palefsky JM
Editorial comment: VACCINES. 2020;8(4):E737-737

DNA Vaccine Development at Pre- and Post-Operation Warp Speed

Ljungberg K; Isaguliants M
Review: BIOCHEMISTRY-MOSCOW. 2019;84(7):800-816

Therapeutic Vaccines Against Human Papilloma Viruses: Achievements and Prospects

Vonsky MS; Runov AL; Gordeychuk IV; Isaguliants MG
Review: BIOCHEMISTRY-MOSCOW. 2019;84(7):782-799

Carcinogenesis Associated with Human Papillomavirus Infection. Mechanisms and Potential for Immunotherapy

Vonsky M; Shabaeva M; Runov A; Lebedeva N; Chowdhury S; Palefsky JM; Isaguliants M
Published conference paper: HUMAN VACCINES & IMMUNOTHERAPEUTICS. 2017;13(12):2849-2858

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses

Stenler S; Lundin KE; Hansen L; Petkov S; Mozafari N; Isaguliants M; Blomberg P; Smith CIE; Goldenberg DM; Chang C-H; Ljungberg K; Hinkula J; Wahren B
Editorial comment: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2017;2017:3496043

Oxidative Stress in Infection and Consequent Disease

Ivanov AV; Bartosch B; Isaguliants MG
Review: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2016;2016:8910396

Oxidative Stress during HIV Infection: Mechanisms and Consequences

Ivanov AV; Valuev-Elliston VT; Ivanova ON; Kochetkov SN; Starodubova ES; Bartosch B; Isaguliants MG
Review: VIRUSES-BASEL. 2013;5(2):439-469

HCV and Oxidative Stress in the Liver

Ivanov AV; Bartosch B; Smirnova OA; Isaguliants MG; Kochetkov SN
Review: ACTA NATURAE. 2010;2(1):53-60

Regulation of Immunogen Processing: Signal Sequences and Their Application for the New Generation of DNA-Vaccines

Starodubova ES; Isaguliants MG; Karpov VL
Published conference paper: JOURNAL OF INFECTIOUS DISEASES. 2008;198(10):1482-1490

Broad Immunogenicity of a Multigene, Multiclade HIV-1 DNA Vaccine Boosted with Heterologous HIV-1 Recombinant Modified Vaccinia Virus Ankara

Sandstrom E; Nilsson C; Hejdeman B; Brave A; Bratt G; Robb M; Cox J; VanCott T; Marovich M; Stout R; Aboud S; Bakari M; Pallangyo K; Ljungberg K; Moss B; Earl P; Michael N; Birx D; Mhalu F; Wahren B; Biberfeld G
Review: VOPROSY VIRUSOLOGII. 2008;53(6):40-45

[Role of a host in spontaneous recovery from viral hepatitis C: genetic predetermined factors].

Isaguliants MG; Ozeretskovskaia NN
Review: VOPROSY VIRUSOLOGII. 2008;53(2):4-9

[Role of host in spontaneous recovery from viral hepatitis C: the body's condition at the moment of infection].

Isaguliants MG; Ozeretskovskaia NN; Znoĭko OO; Tsyganova EV
Review: EXPERT REVIEW OF VACCINES. 2008;7(1):131-145

Vaccination against drug resistance in HIV infection

Boberg A; Isaguliants M
Review: EXPERT REVIEW OF VACCINES. 2007;6(4):527-537

Functionality of the immune system in patients with chronic hepatitis C: trial by superinfections and vaccinations

Isaguliants MG
Meeting abstract: JOURNAL OF CLINICAL VIROLOGY. 2006;36:S120-S121

Spread of the natural hepatitis C virus recombinant outside Russia

Kalinina O; Jern C; Tallo T; Thcakharian V; Gusev D; Znoiko O; Isaguliants M; Mukomolov S; Norder H; Magnius LO
Meeting abstract: JOURNAL OF CLINICAL VIROLOGY. 2006;36:S120

HCV-specific immune responses in HCV-uninfected individuals

Janvier G; Neveu B; Saulquin X; Isaguliants M; Rechkina N; Chaix M; Bonneville M; Mogenet A; Bresson J; Pol S; Riviere Y
Meeting abstract: JOURNAL OF CLINICAL VIROLOGY. 2006;36:S103-S104

Anti-HCV immune response in healthy individuals in contact with chronic HCV carriers

Znoiko O; Petrakova N; Rechkina N; Dudina K; Stepanova N; Malkov I; Yuschuk N; Widell A; Isaguliants M
Review: CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 2003;4(3):185-193

Host background factors contributing to hepatitis C virus clearance.

Isaguliants MG; Ozeretskovskaya NN
Review: CURRENT PHARMACEUTICAL BIOTECHNOLOGY. 2003;4(3):169-183

Hepatitis C virus clearance: the enigma of failure despite an impeccable survival strategy.

Isaguliants MG
Addendum: IMMUNOLOGY LETTERS. 1997;55(1):61

HIV-1 epitopes exposed by hybrid hepatitis B core particles affect proliferation of peripheral blood mononuclear cells from HIV-1 positive donors (vol 52, pg 37, 1996)

Isaguliants MG; Nordlund S; Sallberg M; Smirnov VD; Ruden U; Wahren B
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