Maria Eriksson
Professor | Docent
E-mail: maria.eriksson.2@ki.se
Visiting address: Blickagången 16, 14152 Flemingsberg
Postal address: H7 Medicin, Huddinge, H7 BioNut Eriksson, 171 77 Stockholm
About me
- Maria Eriksson has discovered the gene that causes premature ageing in children. She is now researching the general genetic causes of ageing and has shown, amongst other things, that our stem cells gather more mutations during our lives than previously known.
Research
- “I am studying genetic mechanisms for ageing. We recently showed that stem cells in the muscles of healthy elderly people contain an unexpected number of mutations. There may be thousands of changes in the DNA in a single cell. We can also see clear patterns in this mutation load, as it is known, where certain regions of the genome are more protected. We are now working on publishing similar results for kidney, fat and skin stem cells.
Another line of research is studying by experiment how the disease progeria, premature ageing, expresses itself in cells in the skeleton, blood vessels, fat and skin. I have been researching progeria for a long time and discovered the genetic causes of the disease in 2003. We are now using progeria as a model to help us understand the mechanisms of ageing.”
Articles
- Article: NATURE COMMUNICATIONS. 2022;13(1):6834
- Article: NATURE COMMUNICATIONS. 2022;13(1):3068
- Article: ELIFE. 2021;10:e63284
- Article: AGING CELL. 2020;19(8):e13200
- Article: GENOME BIOLOGY. 2019;20(1):285
- Article: AGING CELL. 2019;18(6):e13010
- Article: NATURE COMMUNICATIONS. 2019;10(1):4990
- Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(11):2272-2280.e12
- Article: HUMAN MOLECULAR GENETICS. 2019;28(16):2675-2685
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2019;129(2):531-545
- Article: SCIENTIFIC REPORTS. 2018;8(1):15368
- Article: NATURE COMMUNICATIONS. 2018;9(1):800
- Article: SCIENTIFIC REPORTS. 2017;7(1):4405
- Article: AGING CELL. 2016;15(2):267-278
- Article: THE FASEB JOURNAL. 2015;29(8):3193-3205
- Article: HUMAN MOLECULAR GENETICS. 2015;24(5):1305-1321
- Article: PLOS ONE. 2015;10(6):e0128917
- Article: AGING CELL. 2014;13(2):292-302
- Article: PLOS ONE. 2014;9(8):e104098
- Article: HUMAN MUTATION. 2013;34(10):1352-1356
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(40):33512-33522
- Article: AGING CELL. 2011;10(6):1011-1020
- Article: BMC RESEARCH NOTES. 2011;4:282
- Article: PLOS ONE. 2011;6(9):e25472
- Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2009;17(7):928-937
- Article: PLOS ONE. 2009;4(1):e4114
- Article: JOURNAL OF MEDICAL GENETICS. 2008;45(12):794-801
- Article: JOURNAL OF CELL SCIENCE. 2008;121(7):969-978
- Article: PLOS ONE. 2007;2(6):e532
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(23):8703-8708
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(9):3250-3255
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2004;101(24):8963-8968
- Article: METHODS IN MOLECULAR BIOLOGY. 2004;277:77-84
- Article: NATURE. 2003;423(6937):293-298
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;286(5):1177-1182
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2001;281(4):835-841
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(26):19964-19969
- Article: NEUROLOGY. 2000;54(6):1218-1221
- Article: HUMAN MOLECULAR GENETICS. 1999;8(6):1053-1060
- Article: ANTISENSE AND NUCLEIC ACID DRUG DEVELOPMENT. 1998;8(6):531-536
- Article: BLOOD COAGULATION AND FIBRINOLYSIS. 1997;8:s39-s42
- Show more
All other publications
- Editorial comment: EUROPEAN HEART JOURNAL. 2023;44(40):4208-4210
- Editorial comment: CIRCULATION. 2023;147(23):1745-1747
- Editorial comment: NATURE REVIEWS GENETICS. 2022;23(11):645-646
- Editorial comment: AGING CELL. 2022;21(5):e13613
- Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2021;384(14):1364-1366
- Editorial comment: NATURE MEDICINE. 2021;27(3):377-379
- Review: INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY. 2019;346:157-200
- Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2017;45(6):1279-1293
- Review: NATURE REVIEWS NEPHROLOGY. 2017;13(8):471-482
- Review: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135(11):2577-2583
- Review: CURRENT AGING SCIENCE. 2010;3(2):81-89
- Thesis / dissertation: 2001
Employments
- Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2024-
Degrees and Education
- Docent, Karolinska Institutet, 2010
- Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2001