Marcus Saarinen

About me
Publications
Public outreach and news

About me

PhD student interested in orphan GPCRs, neuropharmacology and receptor
biology.

Articles

Journal article: NATURE COMMUNICATIONS. 2024;15(1):8176
Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.
Mantas I; Flais I; Masarapu Y; Ionescu T; Frapard S; Jung F; Le Merre P; Saarinen M; Tiklova K; Salmani BY; Gillberg L; Zhang X; Chergui K; Carlén M; Giacomello S; Hengerer B; Perlmann T; Svenningsson P
Article: SCIENCE ADVANCES. 2024;10(32):eadn1524
AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1
Diaz-Holguin A; Saarinen M; Vo DD; Sturchio A; Branzell N; de Vaca IC; Hu H; Mitjavila-Domenech N; Lindqvist A; Baranczewski P; Millan MJ; Yang Y; Carlsson J; Svenningsson P
Journal article: SCIENCE ADVANCES. 2024;10(31):eado9959
Multiplexed mapping of the interactome of GPCRs with receptor activity-modifying proteins
Kotliar IB; Bendes A; Dahl L; Chen Y; Saarinen M; Ceraudo E; Dodig-Crnkovic T; Uhlen M; Svenningsson P; Schwenk JM; Sakmar TP
Journal article: BIORXIV. 2023;:2023.11.22.568247
Expanding the GPCR-RAMP interactome.
Kotliar IB; Bendes A; Dahl L; Chen Y; Saarinen M; Ceraudo E; Dodig-Crnković T; Uhle'n M; Svenningsson P; Schwenk JM; Sakmar TP
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2023;26(9):599-606
In Vitro Comparison of Ulotaront (SEP-363856) and Ralmitaront (RO6889450): Two TAAR1 Agonist Candidate Antipsychotics
Agren R; Betari N; Saarinen M; Zeberg H; Svenningsson P; Sahlholm K
Article: NEUROPSYCHOPHARMACOLOGY. 2022;47(13):2319-2329
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT_1A receptor agonist SEP-383856
Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ; Svenningsson P
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(23):12859
GM1 Is Cytoprotective in GPR37-Expressing Cells and Downregulates Signaling
Hertz E; Saarinen M; Svenningsson P
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2018;61(12):5269-5278
Docking Screens for Dual Inhibitors of Disparate Drug Targets for Parkinson's Disease
Jaiteh M; Zeifman A; Saarinen M; Svenningsson P; Brea J; Loza MI; Carlsson J

All other publications

Thesis / dissertation: 2024
Discrete approaches for leveraging g protein-coupled receptors as therapeutic tools
Saarinen M
Corrigendum: NEUROPSYCHOPHARMACOLOGY. 2023;48(5):846
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT_1A receptor agonist SEP- 363856 (vol 47, pg 2319, 2022)
Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ; Svenningsson P
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2023;48:391
Pharmacological Characterization of Potent Human Trace Amine-Associated Receptor 1 (TAAR1) Agonists
Saarinen M; Diaz A; Agren R; Betari N; Zeberg H; Sahlholm K; Carlsson J; Svenningsson P
Review: MOLECULAR PSYCHIATRY. 2022;27(1):534-558
Update on GPCR-based targets for the development of novel antidepressants
Mantas I; Saarinen M; Xu Z-QD; Svenningsson P
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2022;47:391
TAAR1 Dependent and Independent Actions of the Potential Antipsychotic and Dual TAAR1/5HT1A Receptor Agonist SEP-383856
Svenningson P; Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ

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