Logan Froese

Publications
CV
Public outreach and news

Articles

Article: BIOENGINEERING-BASEL. 2025;12(3):247
Commercial NIRS May Not Detect Hemispheric Regional Disparity in Continuously Measured COx/COx-a: An Exploratory Healthy and Cranial Trauma Time-Series Analysis
Sainbhi AS; Froese L; Stein KY; Vakitbilir N; Gomez A; Islam A; Bergmann T; Silvaggio N; Hayat M; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2025;6(1):232-241
High-Frequency Analysis of the Cerebral Physiological Impact of Ketamine in Acute Traumatic Neural Injury
Mcclarty D; Froese L; Bergmann T; Stein KY; Sainbhi AS; Islam A; Vakitbilir N; Silvaggio N; Marquez I; Gomez A; Zeiler FA
Article: SENSORS. 2025;25(2):586
Characterization of RAP Signal Patterns, Temporal Relationships, and Artifact Profiles Derived from Intracranial Pressure Sensors in Acute Traumatic Neural Injury
Islam A; Sainbhi AS; Stein KY; Vakitbilir N; Gomez A; Silvaggio N; Bergmann T; Hayat M; Froese L; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2024;5(1):916-956
Association Between Clinical Measures of Depth of Sedation and Multimodal Cerebral Physiology in Acute Traumatic Neural Injury
Park K; Froese L; Bergmann T; Gomez A; Sainbhi AS; Vakitbilir N; Islam A; Stein KY; Marquez I; Amenta F; Ibrahim Y; Zeiler FA
Article: SCIENTIFIC REPORTS. 2024;14(1):20737
The association of acute and chronic phase cerebrovascular reactivity with patient reported quality of life following moderate-to-severe traumatic brain injury
Gomez A; Marquez I; Froese L; Bergmann T; Sainbhi AS; Vakitbilir N; Islam A; Stein KY; Zeiler FA
Article: CRITICAL CARE. 2024;28(1):294
Cerebral physiologic insult burden in acute traumatic neural injury: a Canadian High Resolution-TBI (CAHR-TBI) descriptive analysis
Stein KY; Gomez A; Griesdale D; Sekhon M; Bernard F; Gallagher C; Thelin EP; Raj R; Aries M; Froese L; Kramer A; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2024;5(1):813-823
Association of RAP Compensatory Reserve Index with Continuous Multimodal Monitoring Cerebral Physiology, Neuroimaging, and Patient Outcome in Adult Acute Traumatic Neural Injury: A Scoping Review
Islam A; Marquez I; Froese L; Vakitbilir N; Gomez A; Stein KY; Bergmann T; Sainbhi AS; Zeiler FA
Article: BIOMEDICAL SIGNAL PROCESSING AND CONTROL. 2024;95:106403
Time-Series autocorrelative structure of cerebrovascular reactivity metrics in severe neural injury: An evaluation of the impact of data resolution
Sainbhi AS; Vakitbilir N; Gomez A; Stein KY; Froese L; Zeiler FA
Article: COMPUTERS IN BIOLOGY AND MEDICINE. 2024;178:108766
Multivariate modeling and prediction of cerebral physiology in acute traumatic neural injury: A scoping review.
Vakitbilir N; Bergmann T; Froese L; Gomez A; Sainbhi AS; Stein KY; Islam A; Zeiler FA
Article: JOURNAL OF CLINICAL MONITORING AND COMPUTING. 2024;38(4):791-802
Optimal bispectral index exists in healthy patients undergoing general anesthesia: A validation study
Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Marquez I; Amenta F; Park K; Stein KY; Berrington N; Dhaliwal P; Zeiler FA
Article: CRITICAL CARE. 2024;28(1):256
Critical thresholds of long-pressure reactivity index and impact of intracranial pressure monitoring methods in traumatic brain injury
Hong E; Froese L; Ponten E; Fletcher-Sandersjoo A; Tatter C; Hammarlund E; Akerlund CAI; Tjerkaski J; Alpkvist P; Bartek Jr J; Raj R; Lindblad C; Nelson DW; Zeiler FA; Thelin EP
Article: CRITICAL CARE EXPLORATIONS. 2024;6(7):e1111
Microvascular Autoregulation in Skeletal Muscle Using Near-Infrared Spectroscopy and Derivation of Optimal Mean Arterial Pressure in the ICU: Pilot Study and Comparison With Cerebral Near-Infrared Spectroscopy
Mirsajadi A; Erickson D; Alias S; Froese L; Sainbhi AS; Gomez A; Majumdar R; Herath I; Wilson M; Zarychanski R; Zeiler FA; Mendelson AA
Article: NEUROTRAUMA REPORTS. 2024;5(1):483-496
Associations Between Intracranial Pressure Extremes and Continuous Metrics of Cerebrovascular Pressure Reactivity in Acute Traumatic Neural Injury: A Scoping Review
Stein KY; Amenta F; Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Ibrahim Y; Islam A; Bergmann T; Marquez I; Zeiler FA
Article: JOURNAL OF NEUROTRAUMA. 2024;41(7-8):910-923
Intracranial Pressure-Derived Cerebrovascular Reactivity Indices and Their Critical Thresholds: A Canadian High Resolution-Traumatic Brain Injury Validation Study
Stein KY; Froese L; Sekhon M; Griesdale D; Thelin EP; Raj R; Tas J; Aries M; Gallagher C; Bernard F; Gomez A; Kramer AH; Zeiler FA
Article: BIOENGINEERING-BASEL. 2024;11(4):310
Near-Infrared Spectroscopy Regional Oxygen Saturation Based Cerebrovascular Reactivity Assessments in Chronic Traumatic Neural Injury versus in Health: A Prospective Cohort Study
Gomez A; Marquez I; Froese L; Bergmann T; Sainbhi AS; Vakitbilir N; Islam A; Stein KY; Ibrahim Y; Zeiler FA
Article: CRITICAL CARE. 2024;28(1):78
Prognostic value of near-infrared spectroscopy regional oxygen saturation and cerebrovascular reactivity index in acute traumatic neural injury: a CAnadian High-Resolution Traumatic Brain Injury (CAHR-TBI) Cohort Study
Gomez A; Froese L; Griesdale D; Thelin EP; Raj R; van Iperenburg L; Tas J; Aries M; Stein KY; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: SENSORS. 2024;24(2):499
Non-Invasive Estimation of Intracranial Pressure-Derived Cerebrovascular Reactivity Using Near-Infrared Spectroscopy Sensor Technology in Acute Neural Injury: A Time-Series Analysis
Gomez A; Froese L; Bergmann TJG; Sainbhi AS; Vakitbilir N; Islam A; Stein KY; Marquez I; Ibrahim Y; Zeiler FA
Article: BIOENGINEERING-BASEL. 2023;11(1):33
Evaluation of Morlet Wavelet Analysis for Artifact Detection in Low-Frequency Commercial Near-Infrared Spectroscopy Systems
Bergmann T; Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Islam A; Stein K; Marquez I; Amenta F; Park K; Ibrahim Y; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2023;11(1):92
Time spent above optimal cerebral perfusion pressure is not associated with failure to improve in outcome in traumatic brain injury
Stein KY; Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Ibrahim Y; Islam A; Marquez I; Amenta F; Bergmann T; Zeiler FA
Article: BIOENGINEERING-BASEL. 2023;10(10):1124
Temporal Statistical Relationship between Regional Cerebral Oxygen Saturation (rSO₂) and Brain Tissue Oxygen Tension (PbtO₂) in Moderate-to-Severe Traumatic Brain Injury: A Canadian High Resolution-TBI (CAHR-TBI) Cohort Study
Gomez A; Griesdale D; Froese L; Yang E; Thelin EP; Raj R; Aries M; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2023;11(1):57
Statistical properties of cerebral near infrared and intracranial pressure-based cerebrovascular reactivity metrics in moderate and severe neural injury: a machine learning and time-series analysis
Gomez A; Sainbhi AS; Stein KY; Vakitbilir N; Froese L; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2023;11(1):54
The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury
Froese L; Hammarlund E; Akerlund CAI; Tjerkaski J; Hong E; Lindblad C; Nelson DW; Thelin EP; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2023;4(1):478-494
Intracranial Pressure Monitoring and Treatment Thresholds in Acute Neural Injury: A Narrative Review of the Historical Achievements, Current State, and Future Perspectives
Stein KY; Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Ibrahim Y; Zeiler FA
Article: METHODS AND PROTOCOLS. 2023;6(3):58
Non-Invasive Mapping of Cerebral Autoregulation Using Near-Infrared Spectroscopy: A Study Protocol
Sainbhi AS; Vakitbilir N; Gomez A; Stein KY; Froese L; Zeiler FA
Article: JOURNAL OF NEUROTRAUMA. 2023;40(11-12):1098-1111
Impact of Chronological Age and Biological Sex on Cerebrovascular Reactivity in Moderate/Severe Traumatic Brain Injury: A CAnadian High-Resolution Traumatic Brain Injury (CAHR-TBI) Study
Batson C; Froese L; Sekhon M; Griesdale D; Gomez A; Thelin EP; Raj R; Aries M; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2023;4(1):410-419
Discrete Fourier Transform Windowing Techniques for Cerebral Physiological Research in Neural Injury: A Practical Demonstration
Froese L; Sainbhi AS; Gomez A; Marquez I; Amenta F; Batson C; Stein KY; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2023;11(1):30
Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis
Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Marquez I; Amenta F; Stein KY; Zeiler FA
Article: NEUROTRAUMA REPORTS. 2023;4(1):307-317
Cerebrovascular Reactivity Is Not Associated With Therapeutic Intensity in Adult Traumatic Brain Injury: A Validation Study
Froese L; Gomez A; Sainbhi AS; Vakitbilir N; Marquez I; Amenta F; Park K; Stein KY; Thelin EP; Zeiler FA
Article: FRONTIERS IN PHYSIOLOGY. 2023;14:1124268
High spatial and temporal resolution cerebrovascular reactivity for humans and large mammals: A technological description of integrated fNIRS and niABP mapping system
Sainbhi AS; Froese L; Gomez A; Marquez I; Amenta F; Batson C; Stein KY; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2022;10(1):54
Cerebrovascular pressure reactivity and brain tissue oxygen monitoring provide complementary information regarding the lower and upper limits of cerebral blood flow control in traumatic brain injury: a CAnadian High Resolution-TBI (CAHR-TBI) cohort study
Gomez A; Sekhon M; Griesdale D; Froese L; Yang E; Thelin EP; Raj R; Aries M; Gallagher C; Bernard F; Kramer AH; Zeiler FA
Article: ACTA NEUROCHIRURGICA. 2022;164(12):3107-3118
Association between cerebrovascular reactivity in adult traumatic brain injury and improvement in patient outcome over time: an exploratory analysis
Stein KY; Froese L; Gomez A; Sainbhi AS; Batson C; Mathieu F; Zeiler FA
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2022;10(1):33
Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?
Froese L; Gomez A; Sainbhi AS; Batson C; Slack T; Stein KY; Mathieu F; Zeiler FA
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All other publications

Review: FRONTIERS IN NETWORK PHYSIOLOGY. 2025;5:1551043
Multivariate linear time-series modeling and prediction of cerebral physiologic signals: review of statistical models and implications for human signal analytics
Vakitbilir N; Sainbhi AS; Islam A; Gomez A; Stein KY; Froese L; Bergmann T; Mcclarty D; Raj R; Zeiler FA
Review: SENSORS. 2024;24(24):8148
Multivariate Modelling and Prediction of High-Frequency Sensor-Based Cerebral Physiologic Signals: Narrative Review of Machine Learning Methodologies
Vakitbilir N; Islam A; Gomez A; Stein KY; Froese L; Bergmann T; Sainbhi AS; Mcclarty D; Raj R; Zeiler FA
Review: PHYSIOLOGICAL MEASUREMENT. 2024;45(12):12TR01
Artifact identification and removal methodologies for intracranial pressure signals: a systematic scoping review
Bergmann T; Vakitbilir N; Gomez A; Islam A; Stein KY; Sainbhi AS; Silvaggio N; Marquez I; Froese L; Zeiler FA
Review: BIOENGINEERING-BASEL. 2024;11(9):933
Artifact Management for Cerebral Near-Infrared Spectroscopy Signals: A Systematic Scoping Review
Bergmann T; Vakitbilir N; Gomez A; Islam A; Stein KY; Sainbhi AS; Froese L; Zeiler FA
Review: PHYSIOLOGICAL MEASUREMENT. 2024;45(6):06TR01
Continuous monitoring methods of cerebral compliance and compensatory reserve: a scoping review of human literature
Islam A; Froese L; Bergmann T; Gomez A; Sainbhi AS; Vakitbilir N; Stein KY; Marquez I; Ibrahim Y; Zeiler FA
Review: SENSORS. 2024;24(5):1453
Time-Series Modeling and Forecasting of Cerebral Pressure-Flow Physiology: A Scoping Systematic Review of the Human and Animal Literature
Vakitbilir N; Froese L; Gomez A; Sainbhi AS; Stein KY; Islam A; Bergmann TJG; Marquez I; Amenta F; Ibrahim Y; Zeiler FA
Review: PHYSIOLOGICAL MEASUREMENT. 2023;44(7):07tr02
Regional disparity in continuously measured time-domain cerebrovascular reactivity indices: a scoping review of human literature
Sainbhi AS; Marquez I; Gomez A; Stein KY; Amenta F; Vakitbilir N; Froese L; Zeiler FA
Review: ACTA NEUROCHIRURGICA. 2023;165(7):1987-2000
Associations between intracranial pressure thresholds and multimodal monitoring in acute traumatic neural injury: a scoping review
Stein KY; Amenta F; Gomez A; Froese L; Sainbhi AS; Vakitbilir N; Marquez I; Zeiler FA
Review: FRONTIERS IN PHYSIOLOGY. 2023;14:1204874
The effect of burst suppression on cerebral blood flow and autoregulation: a scoping review of the human and animal literature
Siddiqi AZ; Froese L; Gomez A; Sainbhi AS; Stein K; Park K; Vakitbilir N; Zeiler FA
Review: FRONTIERS IN PHYSIOLOGY. 2022;13:934731
The Quantitative Associations Between Near Infrared Spectroscopic Cerebrovascular Metrics and Cerebral Blood Flow: A Scoping Review of the Human and Animal Literature
Gomez A; Sainbhi AS; Froese L; Batson C; Slack T; Stein KYY; Cordingley DMM; Mathieu F; Zeiler FAA
Review: ACTA NEUROCHIRURGICA. 2020;162(7):1647-1662
Alternative continuous intracranial pressure-derived cerebrovascular reactivity metrics in traumatic brain injury: a scoping overview
Hasen M; Gomez A; Froese L; Dian J; Raj R; Thelin EP; Zeiler FA

Employments

Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2027
Research Coordinator, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2024

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