Lisha Wang
Assistant Professor
E-mail: lisha.wang@ki.se
Visiting address: BioClinicum J9:20, Visionsgatan 4, 17164 Solna
Postal address: H1 Neurobiologi, vårdvetenskap och samhälle, H1 Neurogeriatrik Tjernberg, 171 77 Stockholm
About me
2023-present: independent line of research
Development of proteolysis-targeting chimeras (PROTACs) to promote degradation of toxic tau variants for Alzheimer disease
2019-2023: Postdoc
Investigation of protein-protein interactions between chaperone (Hsp90) and co-chaperone (FKBP51), and development of small molecules inhibiting this target
2014-2019: PhD
Pharmacokinetics, bioanalysis, and pharmacodynamics of active natural products on cognition
Research
Development of small molecules targeting protein-protein interactions to bring novel treatment for Alzheimer disease
Teaching
PhD course “Protein Metabolism in Health and Disease” (#2332) at Karolinska Institutet
Articles
- Article: ALZHEIMERS & DEMENTIA. 2025;21(3):e70091
- Journal article: BEHAVIOURAL BRAIN RESEARCH. 2024;471:115142
- Article: SCIENCE. 2024;384(6696):660-665
- Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2024;270:116356
- Article: MOLECULAR NEUROBIOLOGY. 2024;61(3):1479-1494
- Article: FRONTIERS IN PHARMACOLOGY. 2022;13:824138
- Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2021;(173)
- Article: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2021;69(7):2129-2137
- Journal article: ANNALS OF TRANSLATIONAL MEDICINE. 2020;8(6):356
- Journal article: FITOTERAPIA. 2020;141:104450
- Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2019;1112:24-32
- Article: FRONTIERS IN PHARMACOLOGY. 2019;10:1084
- Journal article: BIOMEDICAL CHROMATOGRAPHY. 2018;32(8):e4250
- Journal article: FRONTIERS IN PHARMACOLOGY. 2018;9:902
- Article: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2017;65(20):4066-4073
- Journal article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2017;1052:19-26
- Journal article: FRONTIERS IN PHARMACOLOGY. 2017;8:599
- Journal article: FRONTIERS IN PHARMACOLOGY. 2017;8:101
- Journal article: JOURNAL OF ETHNOPHARMACOLOGY. 2016;194:913-917
- Article: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2016;497(1-2):239-247
- Journal article: MARINE DRUGS. 2013;11(5):1492-1505
- Show more
All other publications
- Review: ALZHEIMERS & DEMENTIA. 2025;21(3):e70048
- Review: CELLS. 2021;10(10):2596
- Review: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2021;209:112915
Grants
- PROTACs: A novel strategy for the treatment of Alzheimer diseaseStratNeuro Funding for postdoctoral researchers
- New treatments and diagnostics for Alzheimer´s diseasePrivate initiative "Innovative ways to fight Alzheimer´s disease - Leif Lundblad Family and others"
- Tore Nilsons Stiftelse För Medicinsk Forskning
- Åhlén stiftelsen
- Gun & Bertil Stohnes Stiftelse
- Stiftelsen för Gamla Tjänarinnor
- Karolinska Institutet Geriatrics Foundation
- Karolinska Institutet Research Foundation Grants
- Karolinska Institutet Loo och Hans Ostermans Stifelse
- A novel treatment strategy for Alzheimer disease by inducing protein-protein interactionsPetrus och Augusta Hedlunds Stiftelse
Employments
- Assistant Professor, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2025-2031
- Postdoctoral Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2019-2021
- Postdoctoral Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2019-2021
Degrees and Education
- PhD, Cognitive Enhancing Effects and Pharmacokinetics of Cajaninstilbene Acid, Chinese Academy of Medical Sciences & Peking Union Medical College, 2019