Lise-Lotte Vedin

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About me

International Coordinator at the International Relations Unit, Research Support and External Relations.

International Coordinator with focus on collaboration with the US, including the Rockefeller
University, National Institutes of Health, Brigham and Women’s
Hospital/Harvard University, also contact for Italy and Australia, as well as Marie Sklodowska-Curie European Joint
Degree (double degree for doctoral students).

Articles

Article: MOLECULAR ONCOLOGY. 2023;17(10):2041-2055
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Haugen MH; Gythfeldt HVDL; Egeland EV; Normann LS; Pandya ADD; Vedin L-L; Juell S; Tenstad E; oy GF; Kristian A; Marangoni E; Sorlie T; Steffensen K; Maelandsmo GM; Engebraaten O
Article: SCIENCE ADVANCES. 2023;9(20):eadf2982
Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior
Delbes A-S; Quinones M; Gobet C; Castel J; Denis RGP; Berthelet J; Weger BD; Challet E; Charpagne A; Metairon S; Piccand J; Kraus M; Rohde BH; Bial J; Wilson EM; Vedin L-L; Minniti ME; Pedrelli M; Parini P; Gachon F; Luquet S
Article: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):296-307
Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice
Pramfalk C; Ahmed O; Pedrelli M; Minniti ME; Luquet S; Denis RG; Olin M; Hardfeldt J; Vedin L-L; Steffensen KR; Ryden M; Hodson L; Eriksson M; Parini P
Article: HEPATOLOGY. 2020;72(2):656-670
Insights From Liver-Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR-Agonist Pharmacodynamics in Humans
Minniti ME; Pedrelli M; Vedin L-L; Delbes A-S; Denis RGP; Oorni K; Sala C; Pirazzini C; Thiagarajan D; Nurmi HJ; Grompe M; Mills K; Garagnani P; Ellis ECS; Strom SC; Luquet SH; Wilson EM; Bial J; Steffensen KR; Parini P
Article: NATURE COMMUNICATIONS. 2019;10(1):1684
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα
Liang N; Damdimopoulos A; Goni S; Huang Z; Vedin L-L; Jakobsson T; Giudici M; Ahmed O; Pedrelli M; Barilla S; Alzaid F; Mendoza A; Schroder T; Kuiper R; Parini P; Hollenberg A; Lefebvre P; Francque S; Van Gaal L; Staels B; Venteclef N; Treuter E; Fan R
Article: DRUGS. 2017;77(15):1613-1621
Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia
Jakobsson T; Vedin L-L; Parini P
Article: JOURNAL OF LIPID RESEARCH. 2017;58(2):420-432
The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis
Ferguson D; Zhang J; Davis MA; Helsley RN; Vedin L-L; Lee RG; Crooke RM; Graham MJ; Allende DS; Parini P; Brown JM
Article: MUCOSAL IMMUNOLOGY. 2014;7(6):1416-1428
The oxysterol receptor LXRβ protects against DSS- and TNBS-induced colitis in mice
Jakobsson T; Vedin L-L; Hassan T; Venteclef N; Greco D; D'Amato M; Treuter E; Gustafsson J-A; Steffensen KR
Article: HEPATOLOGY. 2014;59(5):1791-1802
Estrogen Receptor Ligands Ameliorate Fatty Liver Through a Nonclassical Estrogen Receptor/Liver X Receptor Pathway in Mice
Han S-I; Komatsu Y; Murayama A; Steffensen KR; Nakagawa Y; Nakajima Y; Suzuki M; Oie S; Parini P; Vedin L-L; Kishimoto H; Shimano H; Gustafsson J-A; Yanagisawa J
Article: PLOS ONE. 2014;9(9):e106289
Antiproliferative Effects and Mechanisms of Liver X Receptor Ligands in Pancreatic Ductal Adenocarcinoma Cells
Candelaria NR; Addanki S; Zheng J; Trang N-V; Karaboga H; Dey P; Gabbi C; Vedin L-L; Liu K; Wu W; Jonsson PK; Lin JZ; Su F; Bollu LR; Hodges SE; McElhany AL; Issazadeh MA; Fisher WE; Ittmann MM; Steffensen KR; Gustafsson J-A; Lin C-Y
Article: MOLECULAR CARCINOGENESIS. 2013;52(11):835-844
The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon.
Vedin L-L; Gustafsson J-Å; Steffensen KR
Article: BREAST CANCER RESEARCH. 2013;15(3):R51
Liver x receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism
Trang N-V; Vedin L-L; Liu K; Jonsson P; Lin JZ; Candelaria NR; Candelaria LP; Addanki S; Williams C; Gustafsson J-A; Steffensen KR; Lin C-Y
Article: PLOS ONE. 2012;7(3):e32080
Knockdown of SF-1 and RNF31 Affects Components of Steroidogenesis, TGFβ, and Wnt/β-catenin Signaling in Adrenocortical Carcinoma Cells
Ehrlund A; Jonsson P; Vedin L-L; Williams C; Gustafsson J-A; Treuter E
Article: CARCINOGENESIS. 2009;30(4):575-579
The oxysterol receptor LXR inhibits proliferation of human breast cancer cells
Vedin L-L; Lewandowski SA; Parini P; Gustafsson J-A; Steffensen KR

All other publications

Review: EXPERT OPINION ON THERAPEUTIC TARGETS. 2016;20(1):61-71
The emerging roles of liver X receptors and their ligands in cancer
Lin C-Y; Vedin L-L; Steffensen KR
Doctoral thesis: 2013
The antiproliferative role of the liver X receptors in breast and colorectal cancer
Vedin L-L
Meeting abstract: CANCER RESEARCH. 2013;73(8):1310
Liver X receptor agonist blocks pancreatic cancer cell proliferation.
Candelaria NR; Manchem S; Vu HT; Zheng J; Gabbi C; Dey P; Karaboga H; Lin J; Vedin L-L; Su F; Liu K; Jonsson P; Steffensen KR; Gustafsson J-A; Lin C-Y

Employments

International Coordinator, Professional Services, Karolinska Institutet, 2024-
International Coordinator, Central Administration, Karolinska Institutet, 2025-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Biosciences and Nutrition, Karolinska Institutet, 2013

About me

Articles

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Degrees and Education

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