Linn Öijerstedt

Article: BRAIN. 2023;146(5):2120-2131

Neurodevelopmental effects of genetic frontotemporal dementia in young adult mutation carriers.

Finger E; Malik R; Bocchetta M; Coleman K; Graff C; Borroni B; Masellis M; Laforce R; Greaves CV; Russell LL; Convery RS; Bouzigues A; Cash DM; Otto M; Synofzik M; Rowe JB; Galimberti D; Tiraboschi P; Bartha R; Shoesmith C; Tartaglia MC; van Swieten JC; Seelaar H; Jiskoot LC; Sorbi S; Butler CR; Gerhard A; Sanchez-Valle R; de Mendonça A; Moreno F; Vandenberghe R; Le Ber I; Levin J; Pasquier F; Santana I; Rohrer JD; Ducharme S; Genetic FTD Initiative, GENFI

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2023;94(5):357-368

Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating Scales.

Samra K; Macdougall A; Peakman G; Bouzigues A; Bocchetta M; Cash DM; Greaves CV; Convery RS; van Swieten JC; Jiskoot LC; Seelaar H; Moreno F; Sánchez-Valle R; Laforce R; Graff C; Masellis M; Tartaglia MC; Rowe JB; Borroni B; Finger E; Synofzik M; Galimberti D; Vandenberghe R; de Mendonca A; Butler CR; Gerhard A; Ducharme S; Le Ber I; Tiraboschi P; Santana I; Pasquier F; Levin J; Otto M; Sorbi S; Rohrer JD; Russell LL; Genetic FTD Initiative (GENFI); Genetic FTDInitiative (GENFI)

Article: HUMAN BRAIN MAPPING. 2023;44(7):2684-2700

Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia.

Bussy A; Levy JP; Best T; Patel R; Cupo L; Van Langenhove T; Nielsen JE; Pijnenburg Y; Waldö ML; Remes AM; Schroeter ML; Santana I; Pasquier F; Otto M; Danek A; Levin J; Le Ber I; Vandenberghe R; Synofzik M; Moreno F; de Mendonça A; Sanchez-Valle R; Laforce R; Langheinrich T; Gerhard A; Graff C; Butler CR; Sorbi S; Jiskoot L; Seelaar H; van Swieten JC; Finger E; Tartaglia MC; Masellis M; Tiraboschi P; Galimberti D; Borroni B; Rowe JB; Bocchetta M; Rohrer JD; Devenyi GA; Chakravarty MM; Ducharme S; GENetic Frontotemporal dementia Initiative (GENFI)

Article: ALZHEIMERS & DEMENTIA. 2023;19(5):1947-1962

Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementia.

Whiteside DJ; Malpetti M; Jones PS; Ghosh BCP; Coyle-Gilchrist I; van Swieten JC; Seelaar H; Jiskoot L; Borroni B; Sanchez-Valle R; Moreno F; Laforce R; Graff C; Synofzik M; Galimberti D; Masellis M; Tartaglia MC; Finger E; Vandenberghe R; de Mendonça A; Tagliavini F; Butler CR; Santana I; Ber IL; Gerhard A; Ducharme S; Levin J; Danek A; Otto M; Sorbi S; Pasquier F; Bouzigues A; Russell LL; Rohrer JD; Rowe JB; Rittman T; GENFI consortium

Article: JOURNAL OF NEUROLOGY. 2023;270(4):1976-1988

Language impairment in the genetic forms of behavioural variant frontotemporal dementia.

Samra K; MacDougall AM; Bouzigues A; Bocchetta M; Cash DM; Greaves CV; Convery RS; van Swieten JC; Seelaar H; Jiskoot L; Moreno F; Sanchez-Valle R; Laforce R; Graff C; Masellis M; Tartaglia MC; Rowe JB; Borroni B; Finger E; Synofzik M; Galimberti D; Vandenberghe R; de Mendonça A; Butler CR; Gerhard A; Ducharme S; Le Ber I; Tiraboschi P; Santana I; Pasquier F; Levin J; Otto M; Sorbi S; Rohrer JD; Russell LL; Genetic FTD Initiative (GENFI)

Article: NEUROBIOLOGY OF DISEASE. 2023;179:106068

Early neurotransmitters changes in prodromal frontotemporal dementia: A GENFI study.

Premi E; Pengo M; Mattioli I; Cantoni V; Dukart J; Gasparotti R; Buratti E; Padovani A; Bocchetta M; Todd EG; Bouzigues A; Cash DM; Convery RS; Russell LL; Foster P; Thomas DL; van Swieten JC; Jiskoot LC; Seelaar H; Galimberti D; Sanchez-Valle R; Laforce R; Moreno F; Synofzik M; Graff C; Masellis M; Tartaglia MC; Rowe JB; Tsvetanov KA; Vandenberghe R; Finger E; Tiraboschi P; de Mendonça A; Santana I; Butler CR; Ducharme S; Gerhard A; Levin J; Otto M; Sorbi S; Le Ber I; Pasquier F; Rohrer JD; Borroni B; Genetic Frontotemporal dementia Initiative (GENFI)

Article: BRAIN COMMUNICATIONS. 2023;5(2):fcad061

Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative cohort.

Bocchetta M; Todd EG; Bouzigues A; Cash DM; Nicholas JM; Convery RS; Russell LL; Thomas DL; Malone IB; Iglesias JE; van Swieten JC; Jiskoot LC; Seelaar H; Borroni B; Galimberti D; Sanchez-Valle R; Laforce R; Moreno F; Synofzik M; Graff C; Masellis M; Tartaglia MC; Rowe JB; Vandenberghe R; Finger E; Tagliavini F; de Mendonça A; Santana I; Butler CR; Ducharme S; Gerhard A; Danek A; Levin J; Otto M; Sorbi S; Le Ber I; Pasquier F; Rohrer JD; Genetic Frontotemporal dementia Initiative (GENFI)

Article: BRAIN COMMUNICATIONS. 2023;5(2):fcad036

Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasia.

Samra K; MacDougall AM; Bouzigues A; Bocchetta M; Cash DM; Greaves CV; Convery RS; Hardy C; van Swieten JC; Seelaar H; Jiskoot LC; Moreno F; Sanchez-Valle R; Laforce R; Graff C; Masellis M; Tartaglia MC; Rowe JB; Borroni B; Finger E; Synofzik M; Galimberti D; Vandenberghe R; de Mendonça A; Butler CR; Gerhard A; Ducharme S; Le Ber I; Santana I; Pasquier F; Levin J; Otto M; Sorbi S; Warren JD; Rohrer JD; Russell LL; GENetic Frontotemporal dementia Initiative (GENFI)

Article: JOURNAL OF NEUROLOGY. 2023;270(3):1573-1586

Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study.

Pérez-Millan A; Borrego-Écija S; van Swieten JC; Jiskoot L; Moreno F; Laforce R; Graff C; Masellis M; Tartaglia MC; Rowe JB; Borroni B; Finger E; Synofzik M; Galimberti D; Vandenberghe R; de Mendonça A; Butler CR; Gerhard A; Ducharme S; Le Ber I; Santana I; Pasquier F; Levin J; Otto M; Sorbi S; Tiraboschi P; Seelaar H; Langheinrich T; Rohrer JD; Sala-Llonch R; Sánchez-Valle R; Genetic FTD Initiative, GENFI

Article: JOURNAL OF NEUROLOGY. 2023;270(3):1466-1477

Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales.

Samra K; MacDougall AM; Peakman G; Bouzigues A; Bocchetta M; Cash DM; Greaves CV; Convery RS; van Swieten JC; Jiskoot L; Seelaar H; Moreno F; Sanchez-Valle R; Laforce R; Graff C; Masellis M; Tartaglia C; Rowe JB; Borroni B; Finger E; Synofzik M; Galimberti D; Vandenberghe R; de Mendonça A; Butler CR; Gerhard A; Ducharme S; Le Ber I; Tiraboschi P; Santana I; Pasquier F; Levin J; Otto M; Sorbi S; Rohrer JD; Russell LL; Genetic FTD Initiative (GENFI)

Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2022;9(11):1764-1777

CSF glial markers are elevated in a subset of patients with genetic frontotemporal dementia.

Woollacott IOC; Swift IJ; Sogorb-Esteve A; Heller C; Knowles K; Bouzigues A; Russell LL; Peakman G; Greaves CV; Convery R; Heslegrave A; Rowe JB; Borroni B; Galimberti D; Tiraboschi P; Masellis M; Tartaglia MC; Finger E; van Swieten JC; Seelaar H; Jiskoot L; Sorbi S; Butler CR; Graff C; Gerhard A; Laforce R; Sanchez-Valle R; de Mendonça A; Moreno F; Synofzik M; Vandenberghe R; Ducharme S; Ber IL; Levin J; Otto M; Pasquier F; Santana I; Zetterberg H; Rohrer JD; Genetic FTD Initiative, GENFI

Article: NATURE MEDICINE. 2022;28(10):2194-2206

Temporal order of clinical and biomarker changes in familial frontotemporal dementia.

Staffaroni AM; Quintana M; Wendelberger B; Heuer HW; Russell LL; Cobigo Y; Wolf A; Goh S-YM; Petrucelli L; Gendron TF; Heller C; Clark AL; Taylor JC; Wise A; Ong E; Forsberg L; Brushaber D; Rojas JC; VandeVrede L; Ljubenkov P; Kramer J; Casaletto KB; Appleby B; Bordelon Y; Botha H; Dickerson BC; Domoto-Reilly K; Fields JA; Foroud T; Gavrilova R; Geschwind D; Ghoshal N; Goldman J; Graff-Radford J; Graff-Radford N; Grossman M; Hall MGH; Hsiung G-Y; Huey ED; Irwin D; Jones DT; Kantarci K; Kaufer D; Knopman D; Kremers W; Lago AL; Lapid MI; Litvan I; Lucente D; Mackenzie IR; Mendez MF; Mester C; Miller BL; Onyike CU; Rademakers R; Ramanan VK; Ramos EM; Rao M; Rascovsky K; Rankin KP; Roberson ED; Savica R; Tartaglia MC; Weintraub S; Wong B; Cash DM; Bouzigues A; Swift IJ; Peakman G; Bocchetta M; Todd EG; Convery RS; Rowe JB; Borroni B; Galimberti D; Tiraboschi P; Masellis M; Finger E; van Swieten JC; Seelaar H; Jiskoot LC; Sorbi S; Butler CR; Graff C; Gerhard A; Langheinrich T; Laforce R; Sanchez-Valle R; de Mendonça A; Moreno F; Synofzik M; Vandenberghe R; Ducharme S; Le Ber I; Levin J; Danek A; Otto M; Pasquier F; Santana I; Kornak J; Boeve BF; Rosen HJ; Rohrer JD; Boxer AL; Frontotemporal Dementia Prevention Initiative (FPI

Article: JOURNAL OF NEUROINFLAMMATION. 2022;19(1):217

Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study.

van der Ende EL; Heller C; Sogorb-Esteve A; Swift IJ; McFall D; Peakman G; Bouzigues A; Poos JM; Jiskoot LC; Panman JL; Papma JM; Meeter LH; Dopper EGP; Bocchetta M; Todd E; Cash D; Graff C; Synofzik M; Moreno F; Finger E; Sanchez-Valle R; Vandenberghe R; Laforce R; Masellis M; Tartaglia MC; Rowe JB; Butler C; Ducharme S; Gerhard A; Danek A; Levin J; Pijnenburg YAL; Otto M; Borroni B; Tagliavini F; de Mendonça A; Santana I; Galimberti D; Sorbi S; Zetterberg H; Huang E; van Swieten JC; Rohrer JD; Seelaar H; Genetic Frontotemporal Dementia Initiative (GENFI)

Article: ALZHEIMERS RESEARCH & THERAPY. 2022;14(1):118

Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia.

Sogorb-Esteve A; Nilsson J; Swift IJ; Heller C; Bocchetta M; Russell LL; Peakman G; Convery RS; van Swieten JC; Seelaar H; Borroni B; Galimberti D; Sanchez-Valle R; Laforce R; Moreno F; Synofzik M; Graff C; Masellis M; Tartaglia MC; Rowe JB; Vandenberghe R; Finger E; Tagliavini F; Santana I; Butler CR; Ducharme S; Gerhard A; Danek A; Levin J; Otto M; Sorbi S; Le Ber I; Pasquier F; Gobom J; Brinkmalm A; Blennow K; Zetterberg H; Rohrer JD; GENetic FTD Initiative

Article: JOURNAL OF NEUROLOGY. 2022;269(6):3037-3049

TBK1 haploinsufficiency results in changes in the K63-ubiquitination profiles in brain and fibroblasts from affected and presymptomatic mutation carriers.

Khoshnood B; Ullgren A; Laffita-Mesa J; Öijerstedt L; Patra K; Nennesmo I; Graff C

Article: APPLIED NEUROPSYCHOLOGY-ADULT. 2022;29(1):112-119

A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort.

Moore K; Convery R; Bocchetta M; Neason M; Cash DM; Greaves C; Russell LL; Clarke MTM; Peakman G; van Swieten J; Jiskoot L; Moreno F; Barandiaran M; Sanchez-Valle R; Borroni B; Laforce R; Doré M-C; Masellis M; Tartaglia MC; Graff C; Galimberti D; Rowe JB; Finger E; Synofzik M; Karnath H-O; Vandenberghe R; de Mendonça A; Maruta C; Tagliavini F; Santana I; Ducharme S; Butler C; Gerhard A; Levin J; Danek A; Otto M; Warren JD; Rohrer JD; Genetic FTD Initiative, GENFI*

Article: MOLECULAR NEURODEGENERATION. 2021;16(1):79

A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study.

Bergström S; Öijerstedt L; Remnestål J; Olofsson J; Ullgren A; Seelaar H; van Swieten JC; Synofzik M; Sanchez-Valle R; Moreno F; Finger E; Masellis M; Tartaglia C; Vandenberghe R; Laforce R; Galimberti D; Borroni B; Butler CR; Gerhard A; Ducharme S; Rohrer JD; Månberg A; Graff C; Nilsson P; Genetic Frontotemporal Dementia Initiative (GENFI)

Article: ACTA NEUROPATHOLOGICA COMMUNICATIONS. 2021;9(1):132

Single-cell multimodal analysis in a case with reduced penetrance of Progranulin-Frontotemporal Dementia.

Natarajan K; Eisfeldt J; Hammond M; Laffita-Mesa JM; Patra K; Khoshnood B; Öijerstedt L; Graff C

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2021;92(5):494-501

Modelling the cascade of biomarker changes in GRN-related frontotemporal dementia.

Panman JL; Venkatraghavan V; van der Ende EL; Steketee RME; Jiskoot LC; Poos JM; Dopper EGP; Meeter LHH; Donker Kaat L; Rombouts SARB; Vernooij MW; Kievit AJA; Premi E; Cosseddu M; Bonomi E; Olives J; Rohrer JD; Sánchez-Valle R; Borroni B; Bron EE; Van Swieten JC; Papma JM; Klein S; GENFI consortium investigators

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2021;:jnnp-2020-324106-616

MRI data-driven algorithm for the diagnosis of behavioural variant frontotemporal dementia.

Manera AL; Dadar M; Van Swieten JC; Borroni B; Sanchez-Valle R; Moreno F; Laforce R; Graff C; Synofzik M; Galimberti D; Rowe JB; Masellis M; Tartaglia MC; Finger E; Vandenberghe R; de Mendonca A; Tagliavini F; Santana I; Butler CR; Gerhard A; Danek A; Levin J; Otto M; Frisoni G; Ghidoni R; Sorbi S; Rohrer JD; Ducharme S; Collins DL; FTLDNI investigators; GENFI Consortium

Article: NEURON. 2021;109(3):448-460.e4

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis.

Dewan R; Chia R; Ding J; Hickman RA; Stein TD; Abramzon Y; Ahmed S; Sabir MS; Portley MK; Tucci A; Ibáñez K; Shankaracharya FNU; Keagle P; Rossi G; Caroppo P; Tagliavini F; Waldo ML; Johansson PM; Nilsson CF; American Genome Center (TAGC); FALS Sequencing Consortium; Genomics England Research Consortium; International ALS/FTD Genomics Consortium (iAFGC); International FTD Genetics Consortium (IFGC); International LBD Genomics Consortium (iLBDGC); NYGC ALS Consortium; PROSPECT Consortium; Rowe JB; Benussi L; Binetti G; Ghidoni R; Jabbari E; Viollet C; Glass JD; Singleton AB; Silani V; Ross OA; Ryten M; Torkamani A; Tanaka T; Ferrucci L; Resnick SM; Pickering-Brown S; Brady CB; Kowal N; Hardy JA; Van Deerlin V; Vonsattel JP; Harms MB; Morris HR; Ferrari R; Landers JE; Chiò A; Gibbs JR; Dalgard CL; Scholz SW; Traynor BJ

Article: NEUROIMAGE-CLINICAL. 2021;29:102540

Borrego-Écija S; Sala-Llonch R; van Swieten J; Borroni B; Moreno F; Masellis M; Tartaglia C; Graff C; Galimberti D; Laforce R; Rowe JB; Finger E; Vandenberghe R; Tagliavini F; de Mendonça A; Santana I; Synofzik M; Ducharme S; Levin J; Danek A; Gerhard A; Otto M; Butler C; Frisoni G; Sorbi S; Heller C; Bocchetta M; Cash DM; Convery RS; Moore KM; Rohrer JD; Sanchez-Valle R; Genetic FTD Initiative GENFI

Article: NEUROLOGY. 2020;95(24):e3288-e3302

C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts.

Costa B; Manzoni C; Bernal-Quiros M; Kia DA; Aguilar M; Alvarez I; Alvarez V; Andreassen O; Anfossi M; Bagnoli S; Benussi L; Bernardi L; Binetti G; Blackburn D; Boada M; Borroni B; Bowns L; Bråthen G; Bruni AC; Chiang H-H; Clarimon J; Colville S; Conidi ME; Cope TE; Cruchaga C; Cupidi C; Di Battista ME; Diehl-Schmid J; Diez-Fairen M; Dols-Icardo O; Durante E; Flisar D; Frangipane F; Galimberti D; Gallo M; Gallucci M; Ghidoni R; Graff C; Grafman JH; Grossman M; Hardy J; Hernández I; Holloway GJT; Huey ED; Illán-Gala I; Karydas A; Khoshnood B; Kramberger MG; Kristiansen M; Lewis PA; Lleó A; Madhan GK; Maletta R; Maver A; Menendez-Gonzalez M; Milan G; Miller B; Mol MO; Momeni P; Moreno-Grau S; Morris CM; Nacmias B; Nilsson C; Novelli V; Öijerstedt L; Padovani A; Pal S; Panchbhaya Y; Pastor P; Peterlin B; Piaceri I; Pickering-Brown S; Pijnenburg YAL; Puca AA; Rainero I; Rendina A; Richardson AMT; Rogaeva E; Rogelj B; Rollinson S; Rossi G; Rossmeier C; Rowe JB; Rubino E; Ruiz A; Sanchez-Valle R; Sando SB; Santillo AF; Saxon J; Scarpini E; Serpente M; Smirne N; Sorbi S; Suh E; Tagliavini F; Thompson JC; Trojanowski JQ; Van Deerlin VM; Van der Zee J; Van Broeckhoven C; van Rooij J; Van Swieten JC; Veronesi A; Vitale E; Waldö ML; Woodward C; Yokoyama J; Escott-Price V; Polke JM; Ferrari R; International FTD-Genetics Consortium

Article: CORTEX. 2020;133:384-398

Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort.

Russell LL; Greaves CV; Bocchetta M; Nicholas J; Convery RS; Moore K; Cash DM; van Swieten J; Jiskoot L; Moreno F; Sanchez-Valle R; Borroni B; Laforce R; Masellis M; Tartaglia MC; Graff C; Rotondo E; Galimberti D; Rowe JB; Finger E; Synofzik M; Vandenberghe R; de Mendonça A; Tagliavini F; Santana I; Ducharme S; Butler C; Gerhard A; Levin J; Danek A; Otto M; Warren JD; Rohrer JD; Genetic FTD Initiative, GENFI

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2020;91(12):1325-1328

Abnormal pain perception is associated with thalamo-cortico-striatal atrophy in C9orf72 expansion carriers in the GENFI cohort.

Convery RS; Bocchetta M; Greaves CV; Moore KM; Cash DM; Van Swieten J; Moreno F; Sánchez-Valle R; Borroni B; Laforce R; Masellis M; Tartaglia MC; Graff C; Galimberti D; Rowe JB; Finger E; Synofzik M; Vandenberghe R; de Mendonca A; Tagliavini F; Santana I; Ducharme S; Butler C; Gerhard A; Levin J; Danek A; Otto M; Warren JD; Rohrer JD; Genetic FTD Initiative (GENFI)

Article: ANNALS OF NEUROLOGY. 2020;88(1):113-122

Faster Cortical Thinning and Surface Area Loss in Presymptomatic and Symptomatic C9orf72 Repeat Expansion Adult Carriers.

Le Blanc G; Jetté Pomerleau V; McCarthy J; Borroni B; van Swieten J; Galimberti D; Sanchez-Valle R; LaForce R; Moreno F; Synofzik M; Graff C; Masellis M; Tartaglia MC; Rowe JB; Vandenberghe R; Finger E; Tagliavini F; de Mendonça A; Santana I; Butler C; Gerhard A; Danek A; Levin J; Otto M; Frisoni G; Sorbi S; Rohrer JD; Ducharme S; Genetic Frontotemporal Dementia Initiative (GENFI)

Article: TRANSLATIONAL NEURODEGENERATION. 2020;9(1):27

Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers.

Remnestål J; Öijerstedt L; Ullgren A; Olofsson J; Bergström S; Kultima K; Ingelsson M; Kilander L; Uhlén M; Månberg A; Graff C; Nilsson P

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2020;91(6):612-621

Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.

van der Ende EL; Xiao M; Xu D; Poos JM; Panman JL; Jiskoot LC; Meeter LH; Dopper EG; Papma JM; Heller C; Convery R; Moore K; Bocchetta M; Neason M; Peakman G; Cash DM; Teunissen CE; Graff C; Synofzik M; Moreno F; Finger E; Sánchez-Valle R; Vandenberghe R; Laforce R; Masellis M; Tartaglia MC; Rowe JB; Butler CR; Ducharme S; Gerhard A; Danek A; Levin J; Pijnenburg YA; Otto M; Borroni B; Tagliavini F; de Mendonca A; Santana I; Galimberti D; Seelaar H; Rohrer JD; Worley PF; van Swieten JC; Genetic Frontotemporal Dementia Initiative (GENFI)

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2020;91(3):263-270

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.

Heller C; Foiani MS; Moore K; Convery R; Bocchetta M; Neason M; Cash DM; Thomas D; Greaves CV; Woollacott IO; Shafei R; Van Swieten JC; Moreno F; Sanchez-Valle R; Borroni B; Laforce R; Masellis M; Tartaglia MC; Graff C; Galimberti D; Rowe JB; Finger E; Synofzik M; Vandenberghe R; de Mendonca A; Tagliavini F; Santana I; Ducharme S; Butler CR; Gerhard A; Levin J; Danek A; Frisoni G; Sorbi S; Otto M; Heslegrave AJ; Zetterberg H; Rohrer JD; GENFI

Article: LANCET NEUROLOGY. 2020;19(2):145-156

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.

Moore KM; Nicholas J; Grossman M; McMillan CT; Irwin DJ; Massimo L; Van Deerlin VM; Warren JD; Fox NC; Rossor MN; Mead S; Bocchetta M; Boeve BF; Knopman DS; Graff-Radford NR; Forsberg LK; Rademakers R; Wszolek ZK; van Swieten JC; Jiskoot LC; Meeter LH; Dopper EG; Papma JM; Snowden JS; Saxon J; Jones M; Pickering-Brown S; Le Ber I; Camuzat A; Brice A; Caroppo P; Ghidoni R; Pievani M; Benussi L; Binetti G; Dickerson BC; Lucente D; Krivensky S; Graff C; Öijerstedt L; Fallström M; Thonberg H; Ghoshal N; Morris JC; Borroni B; Benussi A; Padovani A; Galimberti D; Scarpini E; Fumagalli GG; Mackenzie IR; Hsiung G-YR; Sengdy P; Boxer AL; Rosen H; Taylor JB; Synofzik M; Wilke C; Sulzer P; Hodges JR; Halliday G; Kwok J; Sanchez-Valle R; Lladó A; Borrego-Ecija S; Santana I; Almeida MR; Tábuas-Pereira M; Moreno F; Barandiaran M; Indakoetxea B; Levin J; Danek A; Rowe JB; Cope TE; Otto M; Anderl-Straub S; de Mendonça A; Maruta C; Masellis M; Black SE; Couratier P; Lautrette G; Huey ED; Sorbi S; Nacmias B; Laforce R; Tremblay M-PL; Vandenberghe R; Damme PV; Rogalski EJ; Weintraub S; Gerhard A; Onyike CU; Ducharme S; Papageorgiou SG; Ng ASL; Brodtmann A; Finger E; Guerreiro R; Bras J; Rohrer JD; FTD Prevention Initiative

Article: LANCET NEUROLOGY. 2019;18(12):1103-1111

Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study.

van der Ende EL; Meeter LH; Poos JM; Panman JL; Jiskoot LC; Dopper EGP; Papma JM; de Jong FJ; Verberk IMW; Teunissen C; Rizopoulos D; Heller C; Convery RS; Moore KM; Bocchetta M; Neason M; Cash DM; Borroni B; Galimberti D; Sanchez-Valle R; Laforce R; Moreno F; Synofzik M; Graff C; Masellis M; Carmela Tartaglia M; Rowe JB; Vandenberghe R; Finger E; Tagliavini F; de Mendonça A; Santana I; Butler C; Ducharme S; Gerhard A; Danek A; Levin J; Otto M; Frisoni GB; Cappa S; Pijnenburg YAL; Rohrer JD; van Swieten JC; Genetic Frontotemporal dementia Initiative (GENFI)

Article: NEUROBIOLOGY OF AGING. 2019;84:241.e21-241.e25

Confirmation of high frequency of C9orf72 mutations in patients with frontotemporal dementia from Sweden.

Öijerstedt L; Chiang H-H; Björkström J; Forsell C; Lilius L; Lindström A-K; Thonberg H; Graff C

Article: NEUROLOGY. 2019;93(18):e1699-e1706

Ventricular volume expansion in presymptomatic genetic frontotemporal dementia.

Tavares TP; Mitchell DGV; Coleman K; Shoesmith C; Bartha R; Cash DM; Moore KM; van Swieten J; Borroni B; Galimberti D; Tartaglia MC; Rowe J; Graff C; Tagliavini F; Frisoni G; Cappa S; Laforce R; de Mendonça A; Sorbi S; Wallstrom G; Masellis M; Rohrer JD; Finger EC; Genetic FTD Initiative, GENFI

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2019;90(10):1124-1130

Education modulates brain maintenance in presymptomatic frontotemporal dementia.

Gazzina S; Grassi M; Premi E; Cosseddu M; Alberici A; Archetti S; Gasparotti R; Van Swieten J; Galimberti D; Sanchez-Valle R; Laforce RJ; Moreno F; Synofzik M; Graff C; Masellis M; Tartaglia MC; Rowe JB; Vandenberghe R; Finger E; Tagliavini F; de Mendonça A; Santana I; Butler CR; Ducharme S; Gerhard A; Danek A; Levin J; Otto M; Frisoni G; Sorbi S; Padovani A; Rohrer JD; Borroni B; Genetic FTD Initiative, GENFI

Article: ACTA NEUROPATHOLOGICA. 2019;137(6):879-899

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Pottier C; Ren Y; Perkerson RB; Baker M; Jenkins GD; van Blitterswijk M; DeJesus-Hernandez M; van Rooij JGJ; Murray ME; Christopher E; McDonnell SK; Fogarty Z; Batzler A; Tian S; Vicente CT; Matchett B; Karydas AM; Hsiung G-YR; Seelaar H; Mol MO; Finger EC; Graff C; Öijerstedt L; Neumann M; Heutink P; Synofzik M; Wilke C; Prudlo J; Rizzu P; Simon-Sanchez J; Edbauer D; Roeber S; Diehl-Schmid J; Evers BM; King A; Mesulam MM; Weintraub S; Geula C; Bieniek KF; Petrucelli L; Ahern GL; Reiman EM; Woodruff BK; Caselli RJ; Huey ED; Farlow MR; Grafman J; Mead S; Grinberg LT; Spina S; Grossman M; Irwin DJ; Lee EB; Suh E; Snowden J; Mann D; Ertekin-Taner N; Uitti RJ; Wszolek ZK; Josephs KA; Parisi JE; Knopman DS; Petersen RC; Hodges JR; Piguet O; Geier EG; Yokoyama JS; Rissman RA; Rogaeva E; Keith J; Zinman L; Tartaglia MC; Cairns NJ; Cruchaga C; Ghetti B; Kofler J; Lopez OL; Beach TG; Arzberger T; Herms J; Honig LS; Vonsattel JP; Halliday GM; Kwok JB; White CL; Gearing M; Glass J; Rollinson S; Pickering-Brown S; Rohrer JD; Trojanowski JQ; Van Deerlin V; Bigio EH; Troakes C; Al-Sarraj S; Asmann Y; Miller BL; Graff-Radford NR; Boeve BF; Seeley WW; Mackenzie IRA; van Swieten JC; Dickson DW; Biernacka JM; Rademakers R

Article: NEUROBIOLOGY OF AGING. 2019;77:169-177

Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia.

Rittman T; Borchert R; Jones S; van Swieten J; Borroni B; Galimberti D; Masellis M; Tartaglia MC; Graff C; Tagliavini F; Frisoni GB; Laforce R; Finger E; Mendonça A; Sorbi S; Rohrer JD; Rowe JB; Genetic Frontotemporal Dementia Initiative (GENFI)

Article: BRAIN. 2019;142(4):1108-1120

Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study.

Mutsaerts HJMM; Mirza SS; Petr J; Thomas DL; Cash DM; Bocchetta M; de Vita E; Metcalfe AWS; Shirzadi Z; Robertson AD; Tartaglia MC; Mitchell SB; Black SE; Freedman M; Tang-Wai D; Keren R; Rogaeva E; van Swieten J; Laforce R; Tagliavini F; Borroni B; Galimberti D; Rowe JB; Graff C; Frisoni GB; Finger E; Sorbi S; de Mendonça A; Rohrer JD; MacIntosh BJ; Masellis M; GENetic Frontotemporal dementia Initiative (GENFI)

Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2019;6(4):698-707

Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics.

van der Ende EL; Meeter LH; Stingl C; van Rooij JGJ; Stoop MP; Nijholt DAT; Sanchez-Valle R; Graff C; Öijerstedt L; Grossman M; McMillan C; Pijnenburg YAL; Laforce R; Binetti G; Benussi L; Ghidoni R; Luider TM; Seelaar H; van Swieten JC

Article: NEUROIMAGE. 2019;189:645-654

The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint.

Premi E; Calhoun VD; Diano M; Gazzina S; Cosseddu M; Alberici A; Archetti S; Paternicò D; Gasparotti R; van Swieten J; Galimberti D; Sanchez-Valle R; Laforce R; Moreno F; Synofzik M; Graff C; Masellis M; Tartaglia MC; Rowe J; Vandenberghe R; Finger E; Tagliavini F; de Mendonça A; Santana I; Butler C; Ducharme S; Gerhard A; Danek A; Levin J; Otto M; Frisoni G; Cappa S; Sorbi S; Padovani A; Rohrer JD; Borroni B; Genetic FTD Initiative, GENFI

Article: NEUROIMAGE. 2019;188:282-290

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort.

Cury C; Durrleman S; Cash DM; Lorenzi M; Nicholas JM; Bocchetta M; van Swieten JC; Borroni B; Galimberti D; Masellis M; Tartaglia MC; Rowe JB; Graff C; Tagliavini F; Frisoni GB; Laforce R; Finger E; de Mendonça A; Sorbi S; Ourselin S; Rohrer JD; Modat M; Genetic FTD Initiative, GENFI

Article: NEUROIMAGE-CLINICAL. 2019;24:102077

White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study.

Sudre CH; Bocchetta M; Heller C; Convery R; Neason M; Moore KM; Cash DM; Thomas DL; Woollacott IOC; Foiani M; Heslegrave A; Shafei R; Greaves C; van Swieten J; Moreno F; Sanchez-Valle R; Borroni B; Laforce R; Masellis M; Tartaglia MC; Graff C; Galimberti D; Rowe JB; Finger E; Synofzik M; Vandenberghe R; de Mendonça A; Tagliavini F; Santana I; Ducharme S; Butler C; Gerhard A; Levin J; Danek A; Frisoni GB; Sorbi S; Otto M; Zetterberg H; Ourselin S; Cardoso MJ; Rohrer JD; On behalf of, GENFI

Article: NATURE COMMUNICATIONS. 2018;9(1):4273

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.

Young AL; Marinescu RV; Oxtoby NP; Bocchetta M; Yong K; Firth NC; Cash DM; Thomas DL; Dick KM; Cardoso J; van Swieten J; Borroni B; Galimberti D; Masellis M; Tartaglia MC; Rowe JB; Graff C; Tagliavini F; Frisoni GB; Laforce R; Finger E; de Mendonça A; Sorbi S; Warren JD; Crutch S; Fox NC; Ourselin S; Schott JM; Rohrer JD; Alexander DC; Genetic FTD Initiative (GENFI); Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Article: BRAIN. 2018;141(10):2895-2907

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.

Zhang M; Ferrari R; Tartaglia MC; Keith J; Surace EI; Wolf U; Sato C; Grinberg M; Liang Y; Xi Z; Dupont K; McGoldrick P; Weichert A; McKeever PM; Schneider R; McCorkindale MD; Manzoni C; Rademakers R; Graff-Radford NR; Dickson DW; Parisi JE; Boeve BF; Petersen RC; Miller BL; Seeley WW; van Swieten JC; van Rooij J; Pijnenburg Y; van der Zee J; Van Broeckhoven C; Le Ber I; Van Deerlin V; Suh E; Rohrer JD; Mead S; Graff C; Öijerstedt L; Pickering-Brown S; Rollinson S; Rossi G; Tagliavini F; Brooks WS; Dobson-Stone C; Halliday GM; Hodges JR; Piguet O; Binetti G; Benussi L; Ghidoni R; Nacmias B; Sorbi S; Bruni AC; Galimberti D; Scarpini E; Rainero I; Rubino E; Clarimon J; Lleó A; Ruiz A; Hernández I; Pastor P; Diez-Fairen M; Borroni B; Pasquier F; Deramecourt V; Lebouvier T; Perneczky R; Diehl-Schmid J; Grafman J; Huey ED; Mayeux R; Nalls MA; Hernandez D; Singleton A; Momeni P; Zeng Z; Hardy J; Robertson J; Zinman L; Rogaeva E; International FTD-Genomics Consortium (IFGC)

Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2018;5(9):1025-1036

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study.

Jiskoot LC; Bocchetta M; Nicholas JM; Cash DM; Thomas D; Modat M; Ourselin S; Rombouts SARB; Dopper EGP; Meeter LH; Panman JL; van Minkelen R; van der Ende EL; Donker Kaat L; Pijnenburg YAL; Borroni B; Galimberti D; Masellis M; Tartaglia MC; Rowe J; Graff C; Tagliavini F; Frisoni GB; Laforce R; Finger E; de Mendonça A; Sorbi S; Genetic Frontotemporal dementia Initiative (GENFI); Papma JM; van Swieten JC; Rohrer JD

Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2018;89(8):851-858

Downregulation of exosomal miR-204-5p and miR-632 as a biomarker for FTD: a GENFI study.

Schneider R; McKeever P; Kim T; Graff C; van Swieten JC; Karydas A; Boxer A; Rosen H; Miller BL; Laforce R; Galimberti D; Masellis M; Borroni B; Zhang Z; Zinman L; Rohrer JD; Tartaglia MC; Robertson J; Genetic FTD Initiative (GENFI)

Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;65(1):147-163

Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort.

Sellami L; Bocchetta M; Masellis M; Cash DM; Dick KM; van Swieten J; Borroni B; Galimberti D; Tartaglia MC; Rowe JB; Graff C; Tagliavini F; Frisoni G; Finger E; de Mendonça A; Sorbi S; Warren JD; Rohrer JD; Laforce R; Genetic FTD Initiative, GENFI

Article: LANCET NEUROLOGY. 2018;17(6):548-558

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Pottier C; Zhou X; Perkerson RB; Baker M; Jenkins GD; Serie DJ; Ghidoni R; Benussi L; Binetti G; López de Munain A; Zulaica M; Moreno F; Le Ber I; Pasquier F; Hannequin D; Sánchez-Valle R; Antonell A; Lladó A; Parsons TM; Finch NA; Finger EC; Lippa CF; Huey ED; Neumann M; Heutink P; Synofzik M; Wilke C; Rissman RA; Slawek J; Sitek E; Johannsen P; Nielsen JE; Ren Y; van Blitterswijk M; DeJesus-Hernandez M; Christopher E; Murray ME; Bieniek KF; Evers BM; Ferrari C; Rollinson S; Richardson A; Scarpini E; Fumagalli GG; Padovani A; Hardy J; Momeni P; Ferrari R; Frangipane F; Maletta R; Anfossi M; Gallo M; Petrucelli L; Suh E; Lopez OL; Wong TH; van Rooij JGJ; Seelaar H; Mead S; Caselli RJ; Reiman EM; Noel Sabbagh M; Kjolby M; Nykjaer A; Karydas AM; Boxer AL; Grinberg LT; Grafman J; Spina S; Oblak A; Mesulam M-M; Weintraub S; Geula C; Hodges JR; Piguet O; Brooks WS; Irwin DJ; Trojanowski JQ; Lee EB; Josephs KA; Parisi JE; Ertekin-Taner N; Knopman DS; Nacmias B; Piaceri I; Bagnoli S; Sorbi S; Gearing M; Glass J; Beach TG; Black SE; Masellis M; Rogaeva E; Vonsattel J-P; Honig LS; Kofler J; Bruni AC; Snowden J; Mann D; Pickering-Brown S; Diehl-Schmid J; Winkelmann J; Galimberti D; Graff C; Öijerstedt L; Troakes C; Al-Sarraj S; Cruchaga C; Cairns NJ; Rohrer JD; Halliday GM; Kwok JB; van Swieten JC; White CL; Ghetti B; Murell JR; Mackenzie IRA; Hsiung G-YR; Borroni B; Rossi G; Tagliavini F; Wszolek ZK; Petersen RC; Bigio EH; Grossman M; Van Deerlin VM; Seeley WW; Miller BL; Graff-Radford NR; Boeve BF; Dickson DW; Biernacka JM; Rademakers R

Article: ALZHEIMERS RESEARCH & THERAPY. 2018;10(1):46

Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales.

Fumagalli GG; Basilico P; Arighi A; Bocchetta M; Dick KM; Cash DM; Harding S; Mercurio M; Fenoglio C; Pietroboni AM; Ghezzi L; van Swieten J; Borroni B; de Mendonça A; Masellis M; Tartaglia MC; Rowe JB; Graff C; Tagliavini F; Frisoni GB; Laforce R; Finger E; Sorbi S; Scarpini E; Rohrer JD; Galimberti D; Genetic FTD Initiative (GENFI)

Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2018;5(5):583-597

Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers.

Meeter LHH; Gendron TF; Sias AC; Jiskoot LC; Russo SP; Donker Kaat L; Papma JM; Panman JL; van der Ende EL; Dopper EG; Franzen S; Graff C; Boxer AL; Rosen HJ; Sanchez-Valle R; Galimberti D; Pijnenburg YAL; Benussi L; Ghidoni R; Borroni B; Laforce R; Del Campo M; Teunissen CE; van Minkelen R; Rojas JC; Coppola G; Geschwind DH; Rademakers R; Karydas AM; Öijerstedt L; Scarpini E; Binetti G; Padovani A; Cash DM; Dick KM; Bocchetta M; Miller BL; Rohrer JD; Petrucelli L; van Swieten JC; Lee SE

Article: NEUROBIOLOGY OF AGING. 2018;62:191-196

Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study.

Cash DM; Bocchetta M; Thomas DL; Dick KM; van Swieten JC; Borroni B; Galimberti D; Masellis M; Tartaglia MC; Rowe JB; Graff C; Tagliavini F; Frisoni GB; Laforce R; Finger E; de Mendonça A; Sorbi S; Rossor MN; Ourselin S; Rohrer JD; Genetic FTD Initiative, GENFI

Article: NEUROBIOLOGY OF AGING. 2018;62:245.e9-245.e12

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study.

Galimberti D; Fumagalli GG; Fenoglio C; Cioffi SMG; Arighi A; Serpente M; Borroni B; Padovani A; Tagliavini F; Masellis M; Tartaglia MC; van Swieten J; Meeter L; Graff C; de Mendonça A; Bocchetta M; Rohrer JD; Scarpini E; Genetic FTD Initiative (GENFI)

Article: JOURNAL OF MAGNETIC RESONANCE IMAGING. 2018;47(1):131-140

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI).

Mutsaerts HJMM; Petr J; Thomas DL; De Vita E; Cash DM; van Osch MJP; Golay X; Groot PFC; Ourselin S; van Swieten J; Laforce R; Tagliavini F; Borroni B; Galimberti D; Rowe JB; Graff C; Pizzini FB; Finger E; Sorbi S; Castelo Branco M; Rohrer JD; Masellis M; MacIntosh BJ; GENFI investigators

Article: BRAIN. 2017;140(6):1784-1791

Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study.

Premi E; Grassi M; van Swieten J; Galimberti D; Graff C; Masellis M; Tartaglia C; Tagliavini F; Rowe JB; Laforce R; Finger E; Frisoni GB; de Mendonça A; Sorbi S; Gazzina S; Cosseddu M; Archetti S; Gasparotti R; Manes M; Alberici A; Cardoso MJ; Bocchetta M; Cash DM; Ourselin S; Padovani A; Rohrer JD; Borroni B; Genetic FTD Initiative (GENFI)

Article: NEUROIMAGE-CLINICAL. 2017;15:171-180

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort.

Sudre CH; Bocchetta M; Cash D; Thomas DL; Woollacott I; Dick KM; van Swieten J; Borroni B; Galimberti D; Masellis M; Tartaglia MC; Rowe JB; Graff C; Tagliavini F; Frisoni G; Laforce R; Finger E; de Mendonça A; Sorbi S; Ourselin S; Cardoso MJ; Rohrer JD; Genetic FTD Initiative, GENFI

Article: ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY. 2016;3(8):623-636

Neurofilament light chain: a biomarker for genetic frontotemporal dementia.

Meeter LH; Dopper EG; Jiskoot LC; Sanchez-Valle R; Graff C; Benussi L; Ghidoni R; Pijnenburg YA; Borroni B; Galimberti D; Laforce RJ; Masellis M; Vandenberghe R; Ber IL; Otto M; van Minkelen R; Papma JM; Rombouts SA; Balasa M; Öijerstedt L; Jelic V; Dick KM; Cash DM; Harding SR; Jorge Cardoso M; Ourselin S; Rossor MN; Padovani A; Scarpini E; Fenoglio C; Tartaglia MC; Lamari F; Barro C; Kuhle J; Rohrer JD; Teunissen CE; van Swieten JC

Article: JOURNAL OF CLINICAL MEDICINE. 2014;3(1):167-175

Maternal Germinal Trisomy 21 in Down Syndrome.

Hultén MA; Öijerstedt L; Iwarsson E; Jonasson J

Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2013;21(11):1260-1265

Novel progranulin mutations with reduced serum-progranulin levels in frontotemporal lobar degeneration.

Chiang H-H; Forsell C; Lilius L; Öijerstedt L; Thordardottir S; Shanmugarajan K; Westerlund M; Nennesmo I; Thonberg H; Graff C

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