Linda Lindström
Principal Researcher | Docent
E-mail: linda.lindstrom@ki.se
Telephone: +46852488117
Visiting address: BioClinicum Akademiska Stråket 1, 17164 SOLNA
Postal address: K7 Onkologi-Patologi, K7 Forskning Lindström, 171 77 Stockholm
About me
- Associate Professor (Docent) and Group Leader
I am Associate Professor in Cancer Epidemiology and Group Leader at the
Department of Oncology and Pathology. In my group we do breast cancer
research with a translational mindset. Breast cancer is the most common
female cancer and one of the main causes of death in women. It is a
heterogeneous disease both in the sense of primary tumor metastatic capacity
and time to metastatic spread of disease.
We have a specific interest in understanding the reasons behind early and
late risk of fatal disease as is seen in patients with breast cancer. Our
goal is to improve the prediction of patients’ risk which would allow for
aggressive life-threatening cancers to be treated aggressively to prevent
fatal disease, whereas sparing patients with less aggressive disease
unnecessary treatment. My analytical background together with my research
experience shows my strong interest in cancer and breast cancer from an
interdisciplinary perspective.
* 2022-2028: Cancerfonden Senior Investigator Award.
* 2020-2021: Senior researcher position awarded by the KI Board of
Research.
* 2015-2019: Assistant Professor position awarded by the KI Board of
Research.
* 2015-2019: Starting grant by Vetenskapsrådet* *(Swedish Research
Council).
* 2015-2019: Young Investigator award by FORTE.
* 2012-2015: Postdoctoral Research position by Vetenskapsrådet.
* 1997-2001: MSc in Molecular Biotechnology (Civilingenjör), Uppsala
University.
* 2004-2008: PhD in Cancer Epidemiology, MEB, KI.
* 2008-2012: Postdoc at Onk-Pat, KI.
* 2012-2014: Postdoc at Carol Franc Buck Breast Care Center, UCSF, USA.
Research
- *My main research questions:*
* What influences the time to distant metastatic breast cancer disease and
time of treatment benefit?
* How does intratumor heterogeneity and tumor microenvironment impact
patient survival?
* Which factors are important to better understand the long-term risk to die
from breast cancer?
* Why do young women have a worse survival? How does the risk and benefit
from treatment differ in premenopausal vs postmenopausal women?
* Which benign breast diseases increase the risk for a future breast cancer
diagnosis? Age differences?
Articles
- Article: BREAST CANCER RESEARCH. 2024;26(1):38
- Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2023;115(11):1310-1317
- Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p6-01-08-p6-01-08
- Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p3-05-03-p3-05-03
- Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p2-03-11-p2-03-11
- Journal article: CANCER RESEARCH. 2023;83(5_Supplement):p2-03-04-p2-03-04
- Journal article: CANCER RESEARCH. 2023;83(2_Supplement_2):b027
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(35):4071-4082
- Article: NPJ PRECISION ONCOLOGY. 2022;6(1):59
- Article: INTERNATIONAL JOURNAL OF CANCER. 2022;150(12):2072-2082
- Article: EUROPEAN JOURNAL OF CANCER. 2022;162:194-205
- Article: JAMA NETWORK OPEN. 2021;4(6):e2114716
- Article: MOLECULAR AND CLINICAL ONCOLOGY. 2021;14(5):94
- Article: JNCI CANCER SPECTRUM. 2021;5(1):pkaa087-
- Article: NPJ BREAST CANCER. 2021;7(1):2
- Article: ONCOGENE. 2020;39(32):5430-5440
- Article: JAMA ONCOLOGY. 2019;5(9):1304-1309
- Article: BREAST CANCER RESEARCH. 2019;21(1):34
- Article: JNCI CANCER SPECTRUM. 2018;2(3):pky051
- Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2018;110(7):726-733
- Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2018;27(6):1818-1829
- Article: CLINICAL CANCER RESEARCH. 2017;23(24):7512-7520
- Article: CLINICAL CANCER RESEARCH. 2017;23(23):7225-7231
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2017;166(2):593-601
- Article: JAMA ONCOLOGY. 2017;3(11):1503-1510
- Article: EUROPEAN JOURNAL OF CANCER. 2017;84:278-289
- Article: INTERNATIONAL JOURNAL OF CANCER. 2017;141(3):497-502
- Article: INTERNATIONAL JOURNAL OF CANCER. 2017;140(11):2414-2421
- Article: CLINICAL CANCER RESEARCH. 2017;23(10):2584-2592
- Journal article: ANNALS OF ONCOLOGY. 2017;28:i10
- Journal article: CANCER RESEARCH. 2017;77(4_Supplement):pd7-02-pd7-02
- Article: INTERNATIONAL JOURNAL OF CANCER. 2017;140(3):581-590
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2016;160(1):131-143
- Article: CLINICAL CANCER RESEARCH. 2016;22(10):2417-2426
- Article: MOLECULAR ONCOLOGY. 2016;10(4):517-525
- Journal article: CANCER RESEARCH. 2016;76(4_Supplement):p6-09-01-p6-09-01
- Article: ONCOTARGET. 2015;6(32):33306-33318
- Article: MOLECULAR ONCOLOGY. 2015;9(7):1384-1391
- Article: CANCER RESEARCH. 2015;75(12):2445-2456
- Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2015;33(15_suppl):e22090
- Article: ANNALS OF ONCOLOGY. 2015;26(3):517-522
- Article: ANNALS OF ONCOLOGY. 2015;26(1):81-88
- Article: ANNALS OF ONCOLOGY. 2014;25(10):1966-1972
- Article: NATURE COMMUNICATIONS. 2014;5:4051
- Journal article: ANNALS OF ONCOLOGY. 2014;25:i5
- Article: MOLECULAR ONCOLOGY. 2014;8(3):741-752
- Journal article: CANCER RESEARCH. 2012;72:pd06-08-pd06-08
- Article: ANNALS OF ONCOLOGY. 2012;23:x349-x353
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2012;30(21):2601-2608
- Article: BMC CANCER. 2012;12:79
- Article: BREAST CANCER RESEARCH AND TREATMENT. 2011;125(2):553-561
- Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2010;28(15_suppl):1009
- Article: BREAST CANCER RESEARCH. 2010;12(6):R105
- Article: PLOS ONE. 2009;4(5):e5588
- Article: JOURNAL OF CLINICAL ONCOLOGY. 2008;26(25):4086-4091
- Article: THE LANCET ONCOLOGY. 2007;8(11):1001-1006
- Article: CANCER EPIDEMIOLOGY, BIOMARKERS AND PREVENTION. 2007;16(8):1639-1643
- Article: BREAST CANCER RESEARCH. 2007;9(3):R39
- Article: STATISTICS IN MEDICINE. 2006;25(18):3110-3123
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All other publications
- Editorial comment: JAMA ONCOLOGY. 2023;9(9):1199-1201
- Conference publication: ANNALS OF ONCOLOGY. 2022;33:S153-S154
- Conference publication: ANNALS OF ONCOLOGY. 2022;33:S184
- Editorial comment: JAMA NETWORK OPEN. 2021;4(10):e2130925
- Conference publication: ANNALS OF ONCOLOGY. 2021;32:S23
- Conference publication: ANNALS OF ONCOLOGY. 2021;32:S21
- Preprint: BIORXIV. 2020
- Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2018;36(15):e18047
- Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2018;36(15):541
- Conference publication: CANCER RESEARCH. 2017;77:p2-05-03-p2-05-03
- Conference publication: CANCER RESEARCH. 2017;77:p1-07-07-p1-07-07
- Conference publication: CANCER RESEARCH. 2017;77:p1-07-16-p1-07-16
- Conference publication: CANCER RESEARCH. 2017;77:p2-03-03-p2-03-03
- Conference publication: ANNALS OF ONCOLOGY. 2017;28
- Corrigendum: ANNALS OF ONCOLOGY. 2016;27(6):1181
- Conference publication: CANCER RESEARCH. 2016;76
- Conference publication: MODERN PATHOLOGY. 2016;29:33A
- Conference publication: MODERN PATHOLOGY. 2016;29:33A
- Conference publication: LABORATORY INVESTIGATION. 2016;96:33A
- Conference publication: LABORATORY INVESTIGATION. 2016;96:33A
- Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2015;51:S269
- Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2015;33(15):1044
- Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2015;33(15):542
- Conference publication: CANCER RESEARCH. 2015;:p4-11-12-p4-11-12
- Conference publication: CANCER RESEARCH. 2015;75(9_Supplement):pd1-5-pd1-5
- Conference publication: CANCER RESEARCH. 2015;75
- Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2015;33(15)
- Conference publication: BREAST. 2014;23:S12
- Conference publication: CANCER RESEARCH. 2014;:165
- Corrigendum: MOLECULAR ONCOLOGY. 2014;8(6):1159
- Meeting abstract: JOURNAL OF CLINICAL ONCOLOGY. 2014;32(15):e22120
- Meeting abstract: CANCER RESEARCH. 2013;73:p6-06-17-p6-06-17
- Conference publication: CANCER RESEARCH. 2013;73(8):4915
- Conference publication: BREAST. 2011;20:S28-S29
- Conference publication: EUROPEAN JOURNAL OF CANCER. 2011;47:S87
- Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2011;47:S337-S338
- Conference publication: ANNALS OF ONCOLOGY. 2011;22:43
- Conference publication: CANCER RESEARCH. 2010;70:s3-5-s3-5
- Conference publication: CANCER RESEARCH. 2010;70:p6-12-05-p6-12-05
- Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2010;28(15)
- Thesis / dissertation: 2008
- Conference publication: BREAST CANCER RESEARCH AND TREATMENT. 2006;100:S185
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Grants
- Swedish Research Council1 January 2021 - 31 December 2023
- Swedish Research Council for Health Working Life and Welfare1 January 2020 - 31 December 2022
- The prognostic and therapeutic impact of intra-tumor heterogeneity in estrogen receptor-positive breast cancerSwedish Cancer Society1 January 2019
- Swedish Research Council for Health Working Life and Welfare1 January 2015 - 31 December 2018
- Swedish Research Council1 January 2015 - 31 December 2018
- Swedish Research Council1 July 2014 - 30 June 2015
- Swedish Research Council1 January 2012 - 31 December 2013
Employments
- Principal Researcher, Department of Oncology-Pathology, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2018
- Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2008