Leonardo Vargas Vallejo

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Articles

Article: BLOOD. 2012;120(4):768-777
Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques
Skold AE; Hasan M; Vargas L; Saidi H; Bosquet N; Le Grand R; Smith CIE; Spetz A-L
Article: IMMUNOLOGICAL REVIEWS. 2009;228(1):58-73
Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain
Mohamed AJ; Yu L; Backesjo C-M; Vargas L; Faryal R; Aints A; Christensson B; Berglof A; Vihinen M; Nore BF; Smith CIE
Article: JOURNAL OF IMMUNOLOGY. 2009;182(4):2176-2184
Kinetic of RelA activation controls magnitude of TLR-mediated IL-12p40 induction.
Bode KA; Schmitz F; Vargas L; Heeg K; Dalpke AH
Article: BLOOD. 2008;111(9):4617-4626
Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-κB
Yu L; Mohamed AJ; Simonson OE; Vargas L; Blomberg KEM; Bjorkstrand B; Arteaga HJ; Notre BF; Smith CIE
Article: IMMUNOLOGY. 2008;123(2):239-249
Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice
Hasan M; Lopez-Herrera G; Blomberg KEM; Lindvall JM; Berglof A; Smith CIE; Vargas L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(26):18201-18207
Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1
Yu L; Mohamed AJ; Vargas L; Berglof A; Finn G; Lu KP; Smith CIE
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;299(3):510-515
Phosphorylation of Bruton's tyrosine kinase by c-Abl
Bäckesjö CM; Vargas L; Superti-Furga G; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(11):9351-9357
Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx
Vargas L; Nore BF; Berglöf A; Heinonen JE; Mattsson PT; Smith CIE; Mohamed AJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(51):40614-40619
Nucleocytoplasmic shuttling of Bruton's tyrosine kinase
Mohamed AJ; Vargas L; Nore BF; Bäckesjo CM; Christenssonn B; Smith CIE
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(1):145-154
Redistribution of Bruton's tyrosine kinase by activation of phosphatidylinositol 3-kinase and Rho-family GTPases
Nore BF; Vargas L; Mohamed AJ; Brandén LJ; Bäckesjö CM; Islam TC; Mattsson PT; Hultenby K; Christensson B; Smith CIE

All other publications

Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2013;78(2):130-139
Inhibitors of BTK and ITK: State of the New Drugs for Cancer, Autoimmunity and Inflammatory Diseases
Vargas L; Hamasy A; Nore BF; Smith CIE
Review: IMMUNOLOGICAL REVIEWS. 2005;203:200-215
Bruton's tyrosine kinase:: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling
Lindvall JM; Blomberg KEM; Väliaho J; Vargas L; Heinonen JE; Berglöf A; Mohamed AJ; Nore BF; Vihinen M; Smith CIE
Corrigendum: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;301(1):258
Phosphorylation of Bruton's tyrosine kinase by c-Abl (vol 299, pg 510, 2002)
Bäckesjö CM; Vargas L; Superti-Furga G; Smith CIE
Thesis / dissertation: 2002
Subcellular localization and signalling of Brutons tyrosine kinase (Btk)
Vargas-Vallejo, Leonardo

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-2025

Degrees and Education

Doctor Of Philosophy, CLINICAL RESEARCH CENTER, Karolinska Institutet, 2002

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