Lena Ekström
Adjunct Professor | Docent
E-mail: lena.ekstrom@ki.se
Visiting address: Avd.För klinisk Farmakologi C1:68, Karolinska Universitetssjukhuset, 14186 Stockholm
Postal address: H5 Laboratoriemedicin, H5 Klin Farmakologi, 141 52 Huddinge
About me
- Adjunct Professor of Pharmacology specialising in Doping Research at the
Department of Laboratory Medicine as of 1 June 2022.
Primary position: Hospital Chemist at Karolinska University Hospital.
Research
- Lena Ekström researches how doping tests can be improved. Her regular work
is at Karolinska University Hospital’s unit for clinical pharmacology,
which is where the Swedish Doping Control Laboratory is located. Her research
focuses on testosterone, other anabolic steroids and growth hormone, and
erythropoietin (EPO)/./
In clinical studies of healthy study participants given doping classified
drugs, Ekström studies how indicators for doping substances vary in urine or
blood samples over time and between individuals. Sex differences and
fluctuations in women during menstruation are also important aspects of her
work.
As a postdoc researcher, Ekström discovered that a common genetic variation
– the lack of the enzyme UGT2B17 – enables athletes to take
performance-enhancing testosterone without overstepping the general threshold
value in force at the time. The discovery was one reason for the introduction
of personalized threshold limits in international elite sport, based on long
data series.
Articles
- Article: INTERNATIONAL JOURNAL OF QUALITATIVE STUDIES ON HEALTH & WELL-BEING. 2024;19(1):2292826
- Article: DRUG TESTING AND ANALYSIS. 2024;16(11):1319-1322
- Article: DRUG TESTING AND ANALYSIS. 2024;16(8):827-834
- Article: DRUG TESTING AND ANALYSIS. 2023;15(7):769-778
- Article: DRUG TESTING AND ANALYSIS. 2023;15(6):678-688
- Article: DRUG TESTING AND ANALYSIS. 2023;15(6):599-604
- Article: DRUG TESTING AND ANALYSIS. 2023;15(4):465-469
- Article: DRUG TESTING AND ANALYSIS. 2023;15(1):134-138
- Article: DRUG TESTING AND ANALYSIS. 2022;14(8):1377-1386
- Article: EPILEPSY RESEARCH. 2022;182:106897
- Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2022;130(4):492-500
- Article: FRONTIERS IN PHYSIOLOGY. 2022;13:844133
- Article: FRONTIERS IN SPORTS AND ACTIVE LIVING. 2022;4:829940
- Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2021;9(6):e00884
- Article: DRUG TESTING AND ANALYSIS. 2021;13(8):1576-1579
- Article: BMC WOMEN'S HEALTH. 2021;21(1):166
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2021;106(3):697-707
- Article: DRUG TESTING AND ANALYSIS. 2021;13(3):550-557
- Article: FRONTIERS IN REPRODUCTIVE HEALTH. 2021;3:787954
- Article: FRONTIERS IN SPORTS AND ACTIVE LIVING. 2021;3:656413
- Article: FRONTIERS IN PHYSIOLOGY. 2021;12:702305
- Article: INTERNATIONAL JOURNAL OF QUALITATIVE STUDIES ON HEALTH & WELL-BEING. 2021;16(1):1927490
- Article: DRUG TESTING AND ANALYSIS. 2020;12(11-12):1620-1628
- Article: DRUG TESTING AND ANALYSIS. 2020;12(9):1229-1240
- Article: DRUG TESTING AND ANALYSIS. 2020;12(6):720-730
- Article: DRUG TESTING AND ANALYSIS. 2020;12(6):711-719
- Article: MEDICINA. 2020;56(6):E265-265
- Article: DRUG TESTING AND ANALYSIS. 2020;12(4):514-523
- Article: FRONTIERS IN ENDOCRINOLOGY. 2020;11:292
- Article: DRUG TESTING AND ANALYSIS. 2019;11(9):1284-1289
- Article: ENDOCRINE CONNECTIONS. 2019;8(7):1070-1081
- Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES. 2018;37(9):1735-1744
- Article: BMC RESEARCH NOTES. 2018;11(1):619
- Article: JOURNAL OF THE ENDOCRINE SOCIETY. 2018;2(7):597-608
- Article: DRUG TESTING AND ANALYSIS. 2018;10(5):839-848
- Article: DRUG TESTING AND ANALYSIS. 2018;10(4):723-730
- Article: EPILEPSY RESEARCH. 2018;140:199-208
- Article: BMC RESEARCH NOTES. 2018;11(1):51
- Article: DRUG TESTING AND ANALYSIS. 2018;10(7):1070-1075
- Article: BRITISH JOURNAL OF SPORTS MEDICINE. 2017;51(17):1301-1308
- Article: DRUG TESTING AND ANALYSIS. 2017;9(7):994-1000
- Article: DRUG TESTING AND ANALYSIS. 2017;9(7):1034-1042
- Article: HORMONE AND METABOLIC RESEARCH. 2016;48(12):834-839
- Article: ANDROLOGIA. 2016;48(5):595-600
- Article: STEROIDS. 2016;108:105-111
- Article: SUBSTANCE ABUSE: TREATMENT, PREVENTION, AND POLICY. 2016;11:11
- Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2016;118(3):214-218
- Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2015;3(6):e00192
- Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2015;117(4):261-266
- Article: PHARMACOGENOMICS JOURNAL. 2015;15(4):293-297
- Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2015;82(1):55-62
- Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2014;2(6):e00071
- Article: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2014;115(4):366-371
- Journal article: JOURNAL OF HORMONES. 2014;2014(1):1-7
- Article: EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (EJPC). 2014;21(8):1049-1054
- Article: SUBSTANCE ABUSE AND REHABILITATION. 2014;5:121-127
- Article: FRONTIERS IN ENDOCRINOLOGY. 2014;5:50
- Article: FRONTIERS IN GENETICS. 2014;5:58
- Article: FEBS OPEN BIO. 2014;4:886-891
- Article: FRONTIERS IN PHARMACOLOGY. 2014;5:132
- Article: PHARMACOGENETICS AND GENOMICS. 2013;23(12):684-696
- Article: DRUG METABOLISM AND DISPOSITION. 2013;41(9):1610-1615
- Article: DRUG METABOLISM AND DISPOSITION. 2013;41(4):704-708
- Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2013;43(3):248-255
- Article: DRUG METABOLISM AND DISPOSITION. 2013;41(2):291-295
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013;430(1):90-94
- Article: FRONTIERS IN ENDOCRINOLOGY. 2013;4:88
- Article: FRONTIERS IN ENDOCRINOLOGY. 2013;4:75
- Article: FRONTIERS IN ENDOCRINOLOGY. 2013;4:51
- Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2013;61(1):1-7
- Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2012;74(1):3-15
- Article: SUBSTANCE ABUSE: TREATMENT, PREVENTION, AND POLICY. 2012;7:12
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;417(3):1046-1051
- Article: BMJ OPEN. 2012;2(6):e001663
- Article: FRONTIERS IN PHARMACOLOGY. 2012;3:151
- Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2011;127(3-5):295-300
- Article: HEART AND VESSELS. 2011;26(6):628-636
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2011;96(11):3440-3447
- Article: PROSTATE. 2011;71(9):909-914
- Article: PHARMACOGENETICS AND GENOMICS. 2011;21(6):325-332
- Article: PROSTATE. 2010;70(2):200-205
- Article: STEROIDS. 2009;74(12):971-977
- Journal article: INVESTIGATIVE UROLOGY. 2009;181(4):720
- Article: STEROIDS. 2009;74(3):365-368
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2008;93(7):2500-2506
- Article: PHARMACOGENETICS AND GENOMICS. 2008;18(6):477-485
- Article: PROSTATE. 2008;68(5):571-575
- Article: PHARMACOGENOMICS JOURNAL. 2008;8(2):147-151
- Article: PROSTATE. 2007;67(13):1439-1446
- Article: PHARMACOGENOMICS JOURNAL. 2007;7(4):282-289
- Article: JOURNAL OF LIPID RESEARCH. 2007;48(4):944-951
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(7):3810-3820
- Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2006;91(2):687-693
- Article: PHARMACOGENOMICS JOURNAL. 2004;4(4):245-250
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2003;1627(2-3):79-84
- Article: JOURNAL OF HYPERTENSION. 2002;20(8):1543-1550
- Article: FREE RADICAL BIOLOGY AND MEDICINE. 2001;30(5):500-505
- Article: BLOOD CELLS, MOLECULES, AND DISEASES. 2000;26(5):423-426
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(17):13000-13006
- Article: FEBS LETTERS. 2000;471(1):78-82
- Article: BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY. 2000;31(2):107-112
- Article: JOURNAL OF INTERNAL MEDICINE. 1999;246(2):211-218
- Article: THE FEBS JOURNAL. 1999;260(2):409-413
- Article: HUMAN MUTATION. 1999;13(4):294-300
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(14):8871-8877
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1996;228(1):165-170
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All other publications
- Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2018;32:63
- Conference publication: EPILEPSIA. 2018;59:S214
- Conference publication: GYNECOLOGICAL ENDOCRINOLOGY. 2016;32:48
- Conference publication: EPILEPSIA. 2016;57:68
- Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2016;23:504
- Published conference paper: DRUG TESTING AND ANALYSIS. 2015;7(11-12):1063-1070
- Editorial comment: FRONTIERS IN ENDOCRINOLOGY. 2015;6:50
- Review: LAKARTIDNINGEN. 2012;109(29-31):1347-1349
- Review: IN VIVO. 2012;26(4):527-535
- Conference publication: LUMINESCENCE. 2012;27(2):141
- Review: EXPERT OPINION ON DRUG METABOLISM AND TOXICOLOGY. 2009;5(7):731-744
- Conference publication: BASIC AND CLINICAL PHARMACOLOGY AND TOXICOLOGY. 2009;105:44
- Book chapter: OXIDATIVE STRESS, DISEASE AND CANCER. 2006;p. 371-460
- Conference publication: ACTA PHARMACOLOGICA SINICA. 2006;27:231
- Review: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2001;389(1):84-93
- Published conference paper: CHEMICO-BIOLOGICAL INTERACTIONS. 2001;133(1-3):301-303
Employments
- Adjunct Professor, Department of Laboratory Medicine, Karolinska Institutet, 2022-2026
Degrees and Education
- Docent, Karolinska Institutet, 2006
- Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2000