Leire de Campos Mata
Postdoctoral Researcher
E-mail: leire.de.campos.mata@ki.se
Visiting address: Solnavägen 9, 17165 Solna
Postal address: C2 Medicinsk biokemi och biofysik, C2 Immunologi Hammarström, 171 77 Stockholm
About me
- I am a postdoctoral researcher at Karolinska Institutet. My main research of
interest is creating a single-cell atlas of the B cell compartment across
human tissues using state-of-the-art technologies
I am a postdoctoral researcher at Karolinska Institutet. I did my PhD in
Biomedicine at the UPF in Spain. During my PhD I uncovered an unanticipated
role of the exonuclease Xrn1 in translational control under physiological
conditions and in cell adaptation and survival under osmotic stress
conditions. During 2020, I focused my career on the profiling of immune cell
and antibody responses in a cohort of moderate to severe COVID-19 patients.
Additionally, I generated monoclonal antibodies isolated from convalescent
individuals that neutralize SARS-CoV-2 variants of concern as a putative
therapy to treat COVID-19. Nowadays, my main research of interest is creating
a single-cell atlas of the B cell compartment and surrounding
microenvironment across different tissues in deceased healthy individuals
using state-of-the-art technologies such as single cell RNA sequencing.
2021: Postdoctoral researcher at Karolinska Institutet
2019: PhD in biomedicine at Universitat Pompeu Fabra "The exonuclease Xrn1: a
key regulator of gene expression under physiological and perturbed
conditions"
2014: Master in Molecular Biology and Biomedicine at Basque Country
University
2013: Bachelor in Biology at Basque Country University
Articles
- Article: YEAST. 2024;41(7):458-472
- Article: NATURE COMMUNICATIONS. 2024;15(1):1051
- Article: NATURE COMMUNICATIONS. 2022;13(1):2670
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:737083
- Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(9):e1339
- Article: NATURE COMMUNICATIONS. 2019;10(1):1298
All other publications
- Preprint: MEDRXIV. 2020
Grants
- Investigating the impact of air pollution on B cell-mediated immunity in human tissuesTore Nilson Foundation1 January 2024 - 30 September 2024
- Uncovering the role of the cellular exonuclease Xrn1 in infectious and non-infectious cellular perturbationsAgència de Gestió d’Ajuts Universitaris i de Recerca1 March 2016 - 28 February 2019
- Collaboration scholarshipMinisterio de Educación, Cultura y Deporte1 September 2012 - 30 June 2013
Employments
- Postdoctoral Researcher, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2023-2025
- Postdoctoral Researcher, Department of Biosciences and Nutrition, Karolinska Institutet, 2021-2023
- Postdoctoral researcher, Immune responses to SARS-CoV-2 infection and immunization, Institut Hospital del Mar d'Investigacions Mèdiques, 2020-2021
- PhD researcher, The exonuclease Xrn1: a key regulator of gene expression under physiological and perturbed conditions, Pompeu Fabra University, 2015-2019
Degrees and Education
- Master in Molecular Biology and Biomedicine, University of the Basque Country, 2014
- Bachelor in Biology, University of the Basque Country, 2013