Lars Sivars

Publications
CV
Public outreach and news

Articles

Article: MOLECULAR DIAGNOSIS & THERAPY. 2025;:1-12
Human Papillomavirus Type and Viral Load in Relation to Circulating Cell-Free Tumour HPV DNA Level and Survival in Cervical Cancer
Hellman K; Zupancic M; Jylha C; Tham E; Sivars L
Article: CLINICAL CANCER RESEARCH. 2024;30(13):2764-2771
Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylha C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjold M; Tham E; Hellman K
Article: ORAL ONCOLOGY. 2024;151:106749
Human papillomavirus (HPV) load is higher in HPVDNA/p16 positive than in HPVDNA positive/p16 negative oropharyngeal squamous cell carcinoma but does not differ significantly between various subsites or correlate to survival
Zupancic M; Kostopoulou ON; Holzhauser S; Lukoseviciute M; Jylha C; Marklund L; Nasman A; Sivars L; Dalianis T
Article: ACTA ONCOLOGICA. 2023;62(12):1649-1652
Prevalence of human papillomavirus (HPV) types 16 and 18 in cervical cancer in Stockholm, Sweden during 2019-2023 compared to 2003-2008
Sivars L; Holzhauser S; Ramqvist T; Tham E; Hellman K; Dalianis T
Journal article: ANNALS OF ONCOLOGY. 2023;34:s537
Cell-free human papillomavirus (HPV) DNA is a sensitive biomarker for monitoring treatment response and for detecting relapse in locally advanced cervical cancer
Sivars L; Tham E; Hellman K
Article: GYNECOLOGIC ONCOLOGY. 2022;167(1):107-114
Circulating cell-free tumor human papillomavirus DNA is a promising biomarker in cervical cancer
Sivars L; Hellman K; Guterstam YC; Holzhauser S; Nordenskjold M; Falconer H; Palsdottir K; Tham E
Article: ACTA OTO-LARYNGOLOGICA. 2018;138(9):855-858
Human papillomavirus (HPV) is absent in branchial cleft cysts of the neck distinguishing them from HPV positive cystic metastasis
Sivars L; Landin D; Rizzo M; Haeggblom L; Bersani C; Munck-Wikland E; Nasman A; Dalianis T; Marklund L
Article: ONCOTARGET. 2017;8(21):35339-35350
Targeted sequencing of tonsillar and base of tongue cancer and human papillomavirus positive unknown primary of the head and neck reveals prognostic effects of mutated FGFR3
Bersani C; Sivars L; Haeggblom L; DiLorenzo S; Mints M; Ahrlund-Richter A; Tertipis N; Munck-Wikland E; Nasman A; Ramqvist T; Dalianis T
Article: ORAL ONCOLOGY. 2017;68:53-59
A model using concomitant markers for predicting outcome in human papillomavirus positive oropharyngeal cancer
Bersani C; Mints M; Tertipis N; Haeggblom L; Sivars L; Ahrlund-Richter A; Vlastos A; Smedberg C; Grun N; Munck-Wikland E; Nasman A; Ramqvist T; Dalianis T
Article: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK. 2017;39(3):419-426
Human papillomavirus DNA detection in fine-needle aspirates as indicator of human papillomavirus-positive oropharyngeal squamous cell carcinoma: A prospective study
Sivars L; Landin D; Haeggblom L; Tertipis N; Grun N; Bersani C; Marklund L; Ghaderi M; Nasman A; Ramqvist T; Nordfors C; Munck-Wikland E; Tani E; Dalianis T
Article: ANTICANCER RESEARCH. 2017;37(2):665-673
Validation of Human Papillomavirus as a Favourable Prognostic Marker and Analysis of CD8⁺ Tumour-infiltrating Lymphocytes and Other Biomarkers in Cancer of Unknown Primary in the Head and Neck Region
Sivars L; Landin D; Grun N; Vlastos A; Marklund L; Nordemar S; Ramqvist T; Munck-Wikland E; Nasman A; Dalianis T
Article: MOLECULAR AND CLINICAL ONCOLOGY. 2016;5(6):671-674
Human papillomavirus is a favourable prognostic factor in cancer of unknown primary in the head and neck region and in hypopharyngeal cancer (Review)
Sivars L; Bersani C; Grun N; Ramqvist T; Munck-Wikland E; Von Buchwald C; Dalianis T
Article: EUROPEAN JOURNAL OF CANCER. 2015;51(12):1580-1587
A model for predicting clinical outcome in patients with human papillomavirus-positive tonsillar and base of tongue cancer
Tertipis N; Hammar U; Nasman A; Vlastos A; Nordfors C; Grun N; Ahrlund-Richter A; Sivars L; Haeggblom L; Marklund L; Hammarstedt-Nordenvall L; Chaturvedi AK; Munck-Wikland E; Ramqvist T; Bottai M; Dalianis T
Article: CANCER MEDICINE. 2014;3(2):376-384
Human papillomavirus and p53 expression in cancer of unknown primary in the head and neck region in relation to clinical outcome
Sivars L; Nasman A; Tertipis N; Vlastos A; Ramqvist T; Dalianis T; Munck-Wikland E; Nordemar S
Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2013;45(11):878-881
Oral human papillomavirus prevalence in high school students of one municipality in Sweden
Nordfors C; Grun N; Haeggblom L; Tertipis N; Sivars L; Mattebo M; Larsson M; Haggstrom-Nordin E; Tyden T; Ramqvist T; Dalianis T
Article: EUROPEAN JOURNAL OF CANCER. 2013;49(11):2522-2530
CD8⁺ and CD4⁺ tumour infiltrating lymphocytes in relation to human papillomavirus status and clinical outcome in tonsillar and base of tongue squamous cell carcinoma
Nordfors C; Grun N; Tertipis N; Ahrlund-Richter A; Haeggblom L; Sivars L; Du J; Nyberg T; Marklund L; Munck-Wikland E; Nasman A; Ramqvist T; Dalianis T

All other publications

Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S4 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Results and Discussion S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S6 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S4 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S2 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S7 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S7 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Methods S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S8 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S9 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S3 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S4 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S2 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S9 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S8 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Results and Discussion S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Data from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S3 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S6 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S3 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S2 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S3 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Data from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S5 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S2 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Figure S5 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Table S4 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2024
Supplementary Methods S1 from Cell-Free Human Papillomavirus DNA Is a Sensitive Biomarker for Prognosis and for Early Detection of Relapse in Locally Advanced Cervical Cancer
Sivars L; Jylhä C; Crona Guterstam Y; Zupancic M; Lindqvist B; Nordenskjöld M; Tham E; Hellman K
Review: INTERNATIONAL JOURNAL OF CANCER. 2023;152(11):2232-2242
The current status of cell-free human papillomavirus DNA as a biomarker in cervical cancer and other HPV-associated tumors: A review
Sivars L; Palsdottir K; Guterstam YC; Falconer H; Hellman K; Tham E
Doctoral thesis: 2018
Human papillomavirus and other biomarkers in neck masses of unknown origin and in head and neck cancer
Sivars L
Review: ANTICANCER RESEARCH. 2016;36(2):487-493
Human Papillomavirus as a Diagnostic and Prognostic Tool in Cancer of Unknown Primary in the Head and Neck Region
Sivars L; Tani E; Nasman A; Ramqvist T; Munck-Wikland E; Dalianis T
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Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2025-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Oncology-Pathology, Karolinska Institutet, 2018
Degree Of Master Of Science In Medicine, Karolinska Institutet, 2015

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