Lars Larsson
Professor Emeritus/Emerita
E-mail: lars.larsson@ki.se
Visiting address: BioClinicum J5:20, 17176 Solna
Postal address: C3 Fysiologi och farmakologi, C3 FyFa Basal och klinisk muskelbiologi, 171 77 Stockholm
About me
- Lars Larsson received his MD and PhD degrees at Karolinska Institutet. He has a specialist degree in clinical neurophysiology from Karolinska University Hopsital and did his post-doctoral training at the Pennsylvania State University, Padova University and University of Wisconsin-Madison, USA.
Lars Larsson has held the position as the Marie Underhill Noll Professor at the Pennsylvania State University, Professor and Chair at Clinical Neurophysiology, Uppsala University Hospital and was recently (2014) recruited to Karolinska Institutet as part of a strategic recruitment plan. At KI, he is Professor of neurophysiology and group leader of the Basic and clinical muscle biology research group at the Department of Physiology and Pharmacology.
Research
- Lars Larsson's research work has focused on the mechanisms underlying the impaired muscle function associated with aging and primary and secondary myopathies affecting sarcomeric proteins. This work has included the development of methods to study regulation of muscle contraction at the whole muscle, motor unit, muscle cell and motor protein levels as well as the implementation of novel experimental models.
Lars Larsson identified the first ICU patient with critical illness myopathy in Sweden 20 years ago and has since then studied the mechanisms underlying this acquired myopathy in clinical and experimental studies, developed sensitive diagnostic methods and introduced specific intervention strategies.
Articles
- Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2024;222:493-504
- Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2024;209(11):1304-1313
- Article: ACTA PHYSIOLOGICA. 2024;240(5):e14128
- Article: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE. 2023;14(3):1533-1545
- Article: FRONTIERS IN PHYSIOLOGY. 2023;14:1207802
- Article: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE. 2022;13(6):2669-2682
- Article: JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE. 2022;13(4):2162-2174
- Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2022;722:109212
- Article: JOURNAL OF ORTHOPAEDIC RESEARCH. 2022;40(6):1293-1300
- Journal article: THE FASEB JOURNAL. 2022;36(S1)
- Journal article: THE FASEB JOURNAL. 2022;36(S1)
- Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:849973
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(605):eaay9592
- Article: JOURNAL OF PHYSIOLOGY. 2021;599(11):2869-2886
- Article: SKELETAL MUSCLE. 2021;11(1):11
- Article: FRONTIERS IN MEDICINE. 2021;8:672370
- Article: FRONTIERS IN MEDICINE. 2021;8:628029
- Article: MACHINE LEARNING: SCIENCE AND TECHNOLOGY. 2020;1(4):045004
- Article: DIAGNOSTICS. 2020;10(11):E966-966
- Article: NATURE COMMUNICATIONS. 2020;11(1):4479
- Article: ACTA PHYSIOLOGICA. 2020;229(1):e13425
- Article: ACTA PHYSIOLOGICA. 2019;225(2):e13172
- Article: NANO LETTERS. 2018;18(11):7021-7029
- Article: MOLECULAR & CELLULAR PROTEOMICS. 2017;16(6):1081-1097
- Article: COMPREHENSIVE PHYSIOLOGY. 2016;7(1):105-112
- Article: CRITICAL CARE. 2016;20(1):254
- Article: SCIENCE TRANSLATIONAL MEDICINE. 2016;8(350):350ra103
- Article: JOURNAL OF PHYSIOLOGY. 2016;594(15):4371-4388
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2016;37(1-2):41-52
- Article: FRONTIERS IN PHYSIOLOGY. 2016;7:417
- Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2015;583:1-8
- Article: ANALYTICAL CHEMISTRY. 2015;87(16):8399-8406
- Article: REDOX BIOLOGY. 2015;5:267-274
- Article: AGING CELL. 2015;14(2):228-235
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2015;36(2):169-181
- Journal article: CRITICAL CARE. 2015;19(Suppl 1):p250
- Article: EXPERIMENTAL GERONTOLOGY. 2014;59:28-33
- Article: JOURNAL OF PHYSIOLOGY. 2014;592(17):3859-3880
- Article: JOURNAL OF PROTEOMICS. 2014;108:55-64
- Article: BIOLOGY. 2014;3(2):368-382
- Article: PLOS ONE. 2014;9(4):e92622
- Article: JOURNAL OF CELL BIOLOGY. 2013;203(2):345-357
- Article: PHYSIOLOGICAL GENOMICS. 2013;45(12):477-486
- Article: BIOGERONTOLOGY. 2013;14(3):303-323
- Article: BIOGERONTOLOGY. 2013;14(3):293-301
- Article: JOURNAL OF PHYSIOLOGY. 2013;591(9):2333-2344
- Article: PHYSIOLOGICAL GENOMICS. 2013;45(8):312-320
- Article: JOURNAL OF PHYSIOLOGY. 2013;591(5):1385-1402
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2012;303(10):R1090-R1099
- Article: CRITICAL CARE. 2012;16(5):R209
- Article: PHYSIOLOGICAL GENOMICS. 2012;44(18):865-877
- Article: ENDOCRINOLOGY. 2012;153(5):2267-2276
- Article: THE FASEB JOURNAL. 2012;26(3):1077-1085
- Article: CRITICAL CARE MEDICINE. 2012;40(1):79-89
- Article: PHYSIOLOGICAL GENOMICS. 2011;43(24):1334-1350
- Article: BMC GENOMICS. 2011;12:602
- Article: ACTA PHYSIOLOGICA. 2011;202(4):671-681
- Article: THE FASEB JOURNAL. 2011;25(6):1903-1913
- Article: JOURNAL OF PHYSIOLOGY. 2011;589(8):2007-2026
- Journal article: BIOPHYSICAL JOURNAL. 2011;100(3):287a
- Article: PLOS ONE. 2011;6(6):e20558
- Article: PLOS ONE. 2011;6(6):e20876
- Article: JOURNAL OF PHYSIOLOGY. 2010;588(24):5105-5114
- Article: AGING CELL. 2010;9(5):685-697
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(21):9807-9812
- Journal article: THE FASEB JOURNAL. 2010;24(S1):1046.3
- Article: CRITICAL CARE MEDICINE. 2010;38(2):602-611
- Article: PFLUGERS ARCHIV EUROPEAN JOURNAL OF PHYSIOLOGY. 2010;459(3):475-483
- Article: PHYSIOLOGICAL GENOMICS. 2009;39(3):141-159
- Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2009;285(1-2):28-38
- Journal article: NEUROMUSCULAR DISORDERS. 2009;19(8-9):559
- Journal article: NEUROMUSCULAR DISORDERS. 2009;19(8-9):551
- Journal article: NEUROMUSCULAR DISORDERS. 2009;19(8-9):560
- Journal article: NEUROMUSCULAR DISORDERS. 2009;19(8-9):559-560
- Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2009;24(9):1608-1617
- Article: JOURNAL OF APPLIED MICROBIOLOGY. 2009;106(5):1494-1501
- Article: PHYSIOLOGICAL GENOMICS. 2009;36(3):158-166
- Article: EXPERIMENTAL PHYSIOLOGY. 2009;94(1):117-129
- Article: UPSALA JOURNAL OF MEDICAL SCIENCES. 2009;114(4):235-241
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2008;295(3):C722-C731
- Article: ACTA PHYSIOLOGICA. 2008;193(3):275-289
- Article: JOURNAL OF PHYSIOLOGY. 2008;586(12):2993-3004
- Article: EXPERIMENTAL PHYSIOLOGY. 2008;93(4):486-495
- Article: JOURNAL OF NEUROSCIENCE. 2008;28(8):1904-1915
- Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2008;642:92-98
- Article: ACTA MYOLOGICA. 2007;26(3):136-144
- Article: CRITICAL CARE MEDICINE. 2007;35(9):S484-S487
- Article: MOLECULAR MEDICINE. 2007;13(9-10):461-470
- Article: ACTA PHYSIOLOGICA. 2007;190(3):229-241
- Article: JOURNAL OF PHYSIOLOGY. 2007;581(3):1283-1292
- Journal article: ACTA PHYSIOLOGICA. 2007;0(0):070405174852003-???
- Journal article: JOURNAL OF MUSCULOSKELETAL NEURONAL INTERACTIONS. 2007;7(1):56-61
- Article: JOURNAL OF PHYSIOLOGY. 2006;577(1):339-352
- Article: NEUROMUSCULAR DISORDERS. 2006;16(11):782-791
- Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2006;50(9):1058-1067
- Article: INVESTIGATIVE OPHTHALMOLOGY AND VISUAL SCIENCE. 2006;47(10):4188-4193
- Article: PFLUGERS ARCHIV EUROPEAN JOURNAL OF PHYSIOLOGY. 2006;453(1):53-66
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 2006;101(3):906-917
- Article: MAMMALIAN GENOME. 2006;17(6):615-628
- Article: PFLUGERS ARCHIV EUROPEAN JOURNAL OF PHYSIOLOGY. 2006;452(2):222-230
- Article: ANATOMICAL SCIENCE INTERNATIONAL. 2006;81(1):47-49
- Article: ACTA PHYSIOLOGICA. 2006;186(2):151-158
- Article: THE JOURNAL OF GENERAL PHYSIOLOGY. 2006;127(2):95-107
- Journal article: JOURNAL OF BONE AND MINERAL RESEARCH. 2005;20(5):748-757
- Article: PHYSIOLOGICAL GENOMICS. 2005;21(2):184-192
- Journal article: BEHAVIOURAL BRAIN RESEARCH. 2005;158(2):301-310
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2005;288(2):R482-R490
- Journal article: PHYSIOLOGICAL GENOMICS. 2003;16(1):141-152
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2003;285(2):C419-C424
- Journal article: NEUROBIOLOGY OF AGING. 2003;24(1):25-35
- Journal article: CLINICAL NEUROPHYSIOLOGY. 2002;113(8):1325-1338
- Journal article: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2002;57(6):B232-B238
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2002;23(4):317-326
- Article: INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM. 2001;11:S28-S43
- Article: THE FASEB JOURNAL. 2001;15(13):2415-2422
- Article: AMERICAN JOURNAL OF PHYSIOLOGY - CELL PHYSIOLOGY. 2001;280(4):C782-C788
- Journal article: DRUGS AND AGING. 2000;17(4):303-316
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2000;278(6):R1545-R1554
- Journal article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2000;21(4):357-365
- Article: DEVELOPMENT. 2000;127(7):1489-1498
- Article: CRITICAL CARE MEDICINE. 2000;28(1):34-45
- Article: JOURNAL OF PHYSIOLOGY. 1999;520(2):463-471
- Article: CLINICAL SCIENCE. 1999;97(4):449-455
- Article: BONE MARROW TRANSPLANTATION. 1999;23(8):835-837
- Article: PFLUGERS ARCHIV EUROPEAN JOURNAL OF PHYSIOLOGY. 1998;437(1):21-30
- Article: ACTA PHYSIOLOGICA. 1998;163(1):33-40
- Article: MUSCLE AND NERVE. 1997;20(8):948-952
- Article: MUSCLE AND NERVE. 1997;20(8):938-947
- Article: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 1997;18(3):335-344
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;272(2):C638-C649
- Article: JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE. 1997;46(1):5-6
- Article: ACTA PHYSIOLOGICA. 1997;159(1):81-89
- Article: JOURNAL OF APPLIED PHYSIOLOGY. 1997;82(1):182-188
- Article: JOURNAL OF PHYSIOLOGY. 1996;494(2):555-567
- Article: LAKARTIDNINGEN. 1996;93(23):2249-2254
- Article: PFLUGERS ARCHIV EUROPEAN JOURNAL OF PHYSIOLOGY. 1996;432(2):320-328
- Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1996;270(1):C352-C360
- Article: CELL CALCIUM. 1996;19(1):15-27
- Article: FISH PHYSIOLOGY AND BIOCHEMISTRY. 1995;14(6):439-448
- Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 1995;132(2):182-192
- Article: ACTA PHYSIOLOGICA. 1995;154(1):59-64
- Article: ACTA PHYSIOLOGICA. 1995;153(2):109-116
- Journal article: JOURNAL OF PHYSIOLOGY. 1994;481(1):149-161
- Journal article: ACTA PHYSIOLOGICA. 1993;147(2):227-234
- Journal article: ACTA NEUROLOGICA SCANDINAVICA. 1993;87(1):37-42
- Journal article: ACTA PHYSIOLOGICA. 1992;146(4):485-495
- Journal article: JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY. 1992;55(10):916-920
- Journal article: JOURNAL OF BIOMECHANICS. 1992;25(7):747
- Journal article: ACTA PHYSIOLOGICA. 1991;143(4):445-446
- Journal article: ACTA PHYSIOLOGICA. 1991;143(3):345-354
- Journal article: JOURNAL OF PHYSIOLOGY. 1991;443:257-275
- Journal article: AMERICAN JOURNAL OF PHYSIOLOGY. 1991;261(1):C93-101
- Journal article: BRITISH JOURNAL OF SURGERY. 1991;157(5):347-354
- Journal article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 1989;93(1):105-124
- Journal article: JOURNAL OF PHYSIOLOGY. 1989;412:267-276
- Journal article: JOURNAL OF BIOMECHANICS. 1989;22(10):1096
- Journal article: JOURNAL OF BIOMECHANICS. 1989;22(10):981
- Journal article: SCANDINAVIAN JOURNAL OF PLASTIC AND RECONSTRUCTIVE SURGERY AND HAND SURGERY. 1989;23(3):181-186
- Journal article: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1988;515:303-313
- Journal article: JOURNAL OF PHYSIOLOGY. 1987;392:129-145
- Journal article: EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY. 1986;55(2):130-136
- Journal article: ACTA PHYSIOLOGICA. 1985;125(2):235-243
- Journal article: MUSCLE AND NERVE. 1985;8(8):714-722
- Journal article: ACTA PHYSIOLOGICA. 1985;123(4):515-518
- Journal article: ACTA PHYSIOLOGICA. 1983;117(3):469-471
- Journal article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 1982;14(3):203-206
- Journal article: ACTA PHYSIOLOGICA. 1979;107(1):39-46
- Journal article: JOURNAL OF APPLIED PHYSIOLOGY. 1979;46(3):451-456
- Journal article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 1977;9(1):26-30
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All other publications
- Conference publication: THE FASEB JOURNAL. 2022;36
- Review: JOURNAL OF NUTRITION. 2022;152(4):926-938
- Review: DISCOVERIES (CRAIOVA). 2022;10(1):e144
- Book chapter: ACQUIRED NEUROMUSCULAR DISORDERS. 2022;p. 189-212
- Review: CURRENT TREATMENT OPTIONS IN NEUROLOGY. 2022;24(4):173-182
- Preprint: BIORXIV. 2021
- Review: BRITISH JOURNAL OF CANCER. 2021;124(10):1623-1636
- Letter: BRITISH JOURNAL OF ANAESTHESIA. 2020;125(3):e334-e336
- Review: PHYSIOLOGICAL REVIEWS. 2019;99(1):427-511
- Editorial comment: NEUROMUSCULAR DISORDERS. 2018;28(12):1022-1030
- Review: ACTA PHYSIOLOGICA. 2018;222(1)
- Conference publication: THE FASEB JOURNAL. 2017;31
- Conference publication: ACTA PHYSIOLOGICA. 2017;219:6-7
- Review: FRONTIERS IN PHYSIOLOGY. 2016;7:23
- Letter: JOURNAL OF PHYSIOLOGY. 2015;593(15):3391-3392
- Review: PHYSIOLOGICAL REVIEWS. 2015;95(3):1025-1109
- Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2013;65:s36-s37
- Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2013;65:S50-S51
- Meeting abstract: EXPERIMENTAL GERONTOLOGY. 2013;48(7):687-688
- Editorial comment: JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY. 2012;2012:257812-3
- Book chapter: SARCOPENIA – AGE-RELATED MUSCLE WASTING AND WEAKNESS. 2011;p. 55-74
- Meeting abstract: NEUROMUSCULAR DISORDERS. 2009;19(8-9):560-561
- Conference publication: BIOPHYSICAL JOURNAL. 2007;:488A
- Book chapter: GERIATRIC REHABILITATION MANUAL. 2007;p. 9-11
- Conference publication: BIOPHYSICAL JOURNAL. 2005;88(1):635A
- Conference publication: BIOPHYSICAL JOURNAL. 2005;88(1):316A
- Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2004;15:270A
- Book chapter: HANDBOOK OF CLINICAL NEUROPHYSIOLOGY. 2003;p. 119-144
- Conference publication: BIOPHYSICAL JOURNAL. 2001;80(1):89A
- Conference publication: BIOPHYSICAL JOURNAL. 2001;80(1):70A
- Conference publication: BIOPHYSICAL JOURNAL. 2001;80(1):260A-261A
- Published conference paper: ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES. 1999;20(6):413-422
- Published conference paper: ACTA PHYSIOLOGICA. 1999;167(4):327-329
- Published conference paper: ACTA PHYSIOLOGICA. 1999;167(4):325-326
- Published conference paper: ACTA PHYSIOLOGICA. 1999;167(4):317-323
- Published conference paper: ACTA PHYSIOLOGICA. 1999;167(4):313-316
- Editorial comment: ACTA PHYSIOLOGICA. 1999;167(4):299
- Conference publication: BIOPHYSICAL JOURNAL. 1999;76(1):A36
- Conference publication: ANESTHESIOLOGY. 1999;91(3A):U427
- Conference publication: BIOPHYSICAL JOURNAL. 1999;76(1):A52
- Conference publication: BIOPHYSICAL JOURNAL. 1999;76(1):A51
- Conference publication: BIOPHYSICAL JOURNAL. 1999;76(1):A156
- Conference publication: THE FASEB JOURNAL. 1999;13(4):A415
- Conference publication: THE FASEB JOURNAL. 1999;13(4):A85
- Conference publication: THE FASEB JOURNAL. 1999;13(4):A85
- Published conference paper: ACTA PHYSIOLOGICA. 1998;163(3):27-29
- Conference publication: BIOPHYSICAL JOURNAL. 1997;72(2):TH200
- Conference publication: BIOPHYSICAL JOURNAL. 1997;72(2):WAMA8
- Published conference paper: MUSCLE AND NERVE. 1997;5:S74-S78
- Conference publication: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 1996;17(1):129
- Published conference paper: THE JOURNALS OF GERONTOLOGY. SERIES A, BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 1995;50:91-95
- Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1995;753:335-342
- Review: PROGRESS IN NEUROBIOLOGY. 1995;45(5):397-458
- Conference publication: BIOPHYSICAL JOURNAL. 1993;64(2):A253
- Conference publication: BIOPHYSICAL JOURNAL. 1993;64(2):A250
- Conference publication: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 1989;10(2):157
- Conference publication: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 1989;10(2):156
- Conference publication: MUSCLE AND NERVE. 1986;9(5):169
- Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 1983;15(2):160
- Conference publication: ACTA PHYSIOLOGICA. 1980;108(2):A48
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Employments
- Professor Emeritus/Emerita, Department of Physiology and Pharmacology, Karolinska Institutet, 2024-2024
- Professor, Department of Physiology and Pharmacology, Karolinska Institutet, 2020-2024