Lars Forsberg

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About me

I am a engineering physisist and a neuroscientist with a background in brain imaging of ageing and analysis of real-world data in Multiple Sclerosis (MS). I have a special interest in appying machine learning and artificial intelligence to create models of the brain and of patients to understand disease progression.

Articles

Article: JOURNAL OF NEUROLOGY. 2024;271(6):3616-3624

Big Multiple Sclerosis Data network: an international registry research network

Glaser A; Butzkueven H; van der Walt A; Gray O; Spelman T; Zhu C; Trojano M; Iaffaldano P; Battaglia MA; Lucisano G; Vukusic S; Vukusic I; Casey R; Horakova D; Drahota J; Magyari M; Joensen H; Pontieri L; Elberling F; Klyve P; Mouresan EF; Forsberg L; Hillert J
Article: MULTIPLE SCLEROSIS JOURNAL - EXPERIMENTAL, TRANSLATIONAL AND CLINICAL. 2023;9(1):20552173231153557-205521732311535

Proportion and characteristics of secondary progressive multiple sclerosis in five European registries using objective classifiers

Forsberg L; Spelman T; Klyve P; Manouchehrinia A; Ramanujam R; Mouresan E; Drahota J; Horakova D; Joensen H; Pontieri L; Magyari M; Ellenberger D; Stahmann A; Rodgers J; Witts J; Middleton R; Nicholas R; Bezlyak V; Adlard N; Hach T; Lines C; Vukusic S; Soilu-Hanninen M; van der Walt A; Butzkueven H; Iaffaldano P; Trojano M; Glaser A; Hillert J
Article: FRONTIERS IN NEUROLOGY. 2023;14:1274194

Predictors of treatment switching in the Big Multiple Sclerosis Data Network

Spelman T; Magyari M; Butzkueven H; van der Walt A; Vukusic S; Trojano M; Iaffaldano P; Horakova D; Drahota J; Pellegrini F; Hyde R; Duquette P; Lechner-Scott J; Sajedi SA; Lalive P; Shaygannejad V; Ozakbas S; Eichau S; Alroughani R; Terzi M; Girard M; Kalincik T; Grand'Maison F; Skibina O; Khoury SJ; Yamout B; Sa MJ; Gerlach O; Blanco Y; Karabudak R; Oreja-Guevara C; Altintas A; Hughes S; Mccombe P; Ampapa R; de Gans K; Mcguigan C; Soysal A; Prevost J; John N; Inshasi J; Stawiarz L; Manouchehrinia A; Forsberg L; Sellebjerg F; Glaser A; Pontieri L; Joensen H; Rasmussen PV; Sejbaek T; Poulsen MB; Christensen JR; Kant M; Stilund M; Mathiesen H; Hillert J
Article: THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. 2023;16:17562864231198963

The impact of healthcare systems on the clinical diagnosis and disease-modifying treatment usage in relapse-onset multiple sclerosis: a real-world perspective in five registries across Europe

Nicholas R; Rodgers J; Witts J; Lerede A; Friede T; Hillert J; Forsberg L; Glaser A; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Pontieri L; Magyari M; Ellenberger D; Stahmann A; Butzkueven H; Van der Walt A; Bezlyak V; Lines C; Middleton R
Article: MULTIPLE SCLEROSIS JOURNAL. 2022;28(13):2099-2105

The impact of bariatric surgery on disease activity and progression of multiple sclerosis: A nationwide matched cohort study

Anna Karin H; Erik S; Tim S; Lars F; Erik N; Jan H
Article: MULTIPLE SCLEROSIS JOURNAL. 2022;28(7):1051-1059

Increased rate of hospitalisation for COVID-19 among rituximab-treated multiple sclerosis patients: A study of the Swedish multiple sclerosis registry

Spelman T; Forsberg L; McKay K; Glaser A; Hillert J
Article: NEUROLOGY. 2021;97(19):e1870-e1885

Associations of Disease-Modifying Therapies With COVID-19 Severity in Multiple Sclerosis

Simpson-Yap S; De Brouwer E; Kalincik T; Rijke N; Hillert JA; Walton C; Edan G; Moreau Y; Spelman T; Geys L; Parciak T; Gautrais C; Lazovski N; Pirmani A; Ardeshirdavanai A; Forsberg L; Glaser A; McBurney R; Schmidt H; Bergmann AB; Braune S; Stahmann A; Middleton R; Salter A; Fox RJ; van der Walt A; Butzkueven H; Alroughani R; Ozakbas S; Rojas JI; van der Mei I; Nag N; Ivanov R; do Olival GS; Dias AE; Magyari M; Brum D; Mendes MF; Alonso RN; Nicholas RS; Bauer J; Chertcoff AS; Zabalza A; Arrambide G; Fidao A; Comi G; Peeters L
Article: SURGERY FOR OBESITY AND RELATED DISEASES. 2021;17(6):1108-1114

Bariatric and metabolic surgery in patients with morbid obesity and multiple sclerosis-a nationwide, matched cohort study

Stenberg E; Forsberg L; Hedstrom A; Hillert J; Naslund E
Journal article: NEUROLOGY. 2021;96(15_supplement)

Objective classification of multiple sclerosis disease course results in frequent reclassification to secondary progressive multiple sclerosis (4094)

Hillert J; Forsberg L; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Magyari M; Ellenberger D; Stahmann A; Van Der Walt A; Rodgers J; Witts JA; Middleton R; Nicholas R; Bezlyak V; Adlard N; Hach T; Lines C; Glaser A
Article: MULTIPLE SCLEROSIS JOURNAL. 2020;26(10):1157-1162

COVID-19 in people with multiple sclerosis: A global data sharing initiative

Peeters LM; Parciak T; Walton C; Geys L; Moreau Y; De Brouwer E; Raimondi D; Pirmani A; Kalincik T; Edan G; Simpson-Yap S; De Raedt L; Dauxais Y; Gautrais C; Rodrigues PR; McKenna L; Lazovski N; Hillert J; Forsberg L; Spelman T; McBurney R; Schmidt H; Bergmann A; Braune S; Stahmann A; Middleton R; Salter A; Bebo BF; Rojas JI; van der Walt A; Butzkueven H; van der Mei I; Ivanov R; Hellwig K; do Olival GS; Cohen JA; Van Hecke W; Dobson R; Magyari M; Brum DG; Alonso R; Nicholas R; Bauer J; Chertcoff A; de Seze J; Louapre C; Comi G; Rijke N
Article: EUROPACE. 2020;22(4):530-537

Improved brain perfusion after electrical cardioversion of atrial fibrillation

Gardarsdottir M; Sigurdsson S; Aspelund T; Gardarsdottir VA; Forsberg L; Gudnason V; Arnar DO
Article: NEUROIMAGE. 2019;189:307-315

Structural covariability hubs in old age

Forsberg L; Sigurdsson S; Launer LJ; Gudnason V; Ullen F
Article: MEDICAL IMAGE ANALYSIS. 2017;39:133-144

The AGES-Reykjavik study atlases: Non-linear multi-spectral template and atlases for studies of the ageing brain

Forsberg L; Sigurdsson S; Fredriksson J; Egilsdottir A; Oskarsdottir B; Kjartansson O; van Buchem MA; Launer LJ; Gudnason V; Zijdenbos A
Article: HUMAN BRAIN MAPPING. 2017;38(1):151-164

Allometric scaling of brain regions to intra-cranial volume: An epidemiological MRI study

de Jong LW; Vidal J-S; Forsberg LE; Zijdenbos AP; Haight T; Sigurdsson S; Gudnason V; van Buchem MA; Launer LJ
Article: FRONTIERS IN SYSTEMS NEUROSCIENCE. 2017;11:14

Breaking the Excitation-Inhibition Balance Makes the Cortical Network's Space-Time Dynamics Distinguish Simple Visual Scenes

Roland PE; Bonde LH; Forsberg LE; Harvey MA
Article: FRONTIERS IN SYSTEMS NEUROSCIENCE. 2016;10:65

The Second Spiking Threshold: Dynamics of Laminar Network Spiking in the Visual Cortex

Forsberg LE; Bonde LH; Harvey MA; Roland PE
Article: PLOS ONE. 2015;10(12):e0144743

Feasibility of Using Pseudo-Continuous Arterial Spin Labeling Perfusion in a Geriatric Population at 1.5 Tesla

Sigurdsson S; Forsberg L; Aspelund T; van der Geest RJ; van Buchem MA; Launer LJ; Gudnason V; van Osch MJ
Article: NEUROBIOLOGY OF AGING. 2014;35(1):72-78

Different susceptibility of medial temporal lobe and basal ganglia atrophy rates to vascular risk factors

de Jong LW; Forsberg LE; Vidal J-S; Sigurdsson S; Zijdenbos AP; Garcia M; Eiriksdottir G; Gudnason V; van Buchem MA; Launer LJ
Article: NEUROIMAGE. 2012;59(4):3862-3870

Brain tissue volumes in the general population of the elderly The AGES-Reykjavik Study

Sigurdsson S; Aspelund T; Forsberg L; Fredriksson J; Kjartansson O; Oskarsdottir B; Jonsson PV; Eiriksdottir G; Harris TB; Zijdenbos A; van Buchem MA; Launer LJ; Gudnason V
Article: ACTA NEUROBIOLOGIAE EXPERIMENTALIS. 2012;72(4):439-451

Switching handedness: fMRI study of hand motor control in right-handers, left-handers and converted left-handers

Grabowska A; Gut M; Binder M; Forsberg L; Rymarczyk K; Urbanik A
Article: ACTA NEUROBIOLOGIAE EXPERIMENTALIS. 2007;67(1):43-51

Brain correlates of right-handedness

Gut M; Urbanik A; Forsberg L; Binder M; Rymarczyk K; Sobiecka B; Kozub J; Grabowska A
Article: TRENDS IN NEUROSCIENCES. 2001;24(10):562-564

A database generator for human brain imaging

Roland P; Svensson G; Lindeberg T; Risch T; Baumann P; Dehmel A; Frederiksson J; Halldorson H; Forsberg L; Young J; Zilles K
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All other publications

Conference publication: NEUROLOGY. 2023;100(17)

Long-term Survival in Multiple Sclerosis is Improving

Wergeland S; Mannseth J; Atula S; Forsberg L; Glaser A; Joensen H; Magyari M; Soilu-Hanninen M; Viitala M; Hillert J; Grytten N
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:790

Impact of COVID-19 infection on cognitive performance in MS patients at Karolinska University Hospital

Loowf I; Hillert J; Forsberg L; Karrenbauer VD
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:419-420

Assessing likelihood of secondary progressive multiple sclerosis in Sweden and Denmark: A federated learning analysis unveiling modestly higher odds in Sweden

Forsberg L; Hillert J; Mouresan EF; Glaser A; Magyari M; Pontieri L
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:640-641

Long term treatment pathways and switch patterns in the Swedish MS Registry - a comparison of clinical outcomes in the TREPASMUS study

Spelman T; Glaser A; Forsberg L; Qu Y; Gandhi K; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:112

A decreasing risk of secondary progressive multiple sclerosis in Sweden 2005-2020

Mouresan EF; Forsberg L; Glaser A; Hillert J
Meeting abstract: MULTIPLE SCLEROSIS JOURNAL. 2023;29:785-786

The effect of COVID-19 infection on physical disability progression in MS patients at Karolinska University Hospital

Tursunova K; Hillert J; Forsberg L; Karrenbauer VD
Thesis / dissertation: 2022

Principles of regional covariance in brain structure

Forsberg, Lars
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):66-67

Rate of disability progression assessed by EDSS, orchestrated by age at MS onset

Stawiarz L; Forsberg L; Hagel E; Fertner A; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):483-484

Predicting expanded disability status scale (EDSS) Using patient reported outcomes (PROs)

Forsberg L; Hillert J; Glaser A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):81

Short-term change in disability and processing speed, but not relapse rate, predicts health related quality of life five and ten years later

Forsberg L; Dormont F; Hillert J; Glaser A
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):682-683

Prevalence and characteristics of MS patients with COVID-19 infection at Karolinska University Hospital, Stockholm, Sweden

Nygard L; Karrenbauer V; Forsberg L
Preprint: MEDRXIV. 2021

Associations of DMT therapies with COVID-19 severity in multiple sclerosis

Simpson-Yap S; De Brouwer E; Kalincik T; Rijke N; Hillert J; Walton C; Edan G; Moreau Y; Spelman T; Geys L; Parciak T; Gautrais C; Lazovski N; Pirmani A; Ardeshirdavani A; Forsberg L; Glaser A; McBurney R; Schmidt H; Bergmann A; Braune S; Stahmann A; Middleton R; Salter A; Fox RJ; van der Walt A; Butzkueven H; Al-Roughani R; Ozakbas S; Rojas JI; van der Mei I; Nag N; Ivanov R; do Olival GS; Dias AE; Magyari M; Brum DG; Mendes MF; Alonso R; Nicholas R; Bauer J; Chertcoff A; Zabalza A; Arrambide G; Fidao A; Comi G; Peeters LM
Conference publication: NEUROLOGY. 2021;96(15)

Modelling Disability Progression in Patients with Secondary Progressive Multiple Sclerosis Shows Non-linearity of EDSS Changes over Time

Bezlyak V; Forsberg L; Klyve P; Adlard N; Hach T; Lines C; Glaser A; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):763-764

Increased rate of hospitalisation for COVID-19 amongst rituximab treated multiple sclerosis patients in Sweden: new data from the 2021 update

Spelman T; Forsberg L; Mckay K; Glaser A; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):521

Swedish MS registry data improvement and evaluation study: Which CSF variable reflects best MRI activity in MS patients

Masood AA; Forsberg L; Mentesidou E; Hillert J; Karrenbauer VD
Conference publication: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2021;50

Associations of DMT therapies with COVID-19 severity in multiple sclerosis

Simpson-Yap S; De Brouwer E; Kalincik T; Rijke N; Hillert J; Walton C; Edan G; Spelman T; Geyes L; Parciak T; Gautrais C; Lazovski N; Pirmani A; Ardeshirdavani A; Forsberg L; Glaser A; McBurney R; Schmidt H; Bergmann A; Braune S; Stahmann A; Middleton R; Salter A; Fox R; van der Walt A; Butzkueven H; Rojas J; van der Mei I; Nag N; Ivanov R; do Olival GS; Dias AE; Magyari M; Brum DG; Mendes MF; Alonso R; Nicholas R; Bauer J; Chertcoff A; Zabalza A; Arrambide G; Fidao A; Comi G; Peeters L
Preprint: SSRN ELECTRONIC JOURNAL. 2021

Increased Rate of Hospitalisation for COVID-19 Amongst Rituximab Treated Multiple Sclerosis Patients: A Study of the Swedish MS Registry

Spelman T; Forsberg L; McKay K; Glaser A; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):201-202

Contributors to secondary progressive multiple sclerosis conversion age - a federated learning analysis across five European MS registries

Forsberg L; Glaser A; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Pontieri L; Magyari M; Ellenberger D; Stahmann A; Van der Walt A; Rodgers J; Witts J; Middleton R; Nicholas R; Bezlyak V; Lines C; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):138-139

Treatment patterns in secondary progressive multiple sclerosis a multi-country registry study from five European countries

Rodgers J; Witts J; Middleton R; Hillert J; Forsberg L; Glaser A; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Pontieri L; Magyari M; Ellenberger D; Stahmann A; Van der Walt A; Bezlyak V; Lines C; Nicholas R
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):204-205

Demographic and clinical characteristics of treated and untreated patients with secondary progressive multiple sclerosis - analysis from three European registries

Pontieri L; Joensen H; Kopp TI; Forsberg L; Glaser A; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Hillert J; Drahota J; Horakova D; Bezlyak V; Lines C; Magyari M
Conference publication: NEUROLOGY. 2021;96(15)

Objective classification of multiple sclerosis disease course results in frequent reclassification to secondary progressive multiple sclerosis

Hillert J; Forsberg L; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Magyari M; Ellenberger D; Stahmann A; Van der Walt A; Rodgers J; Witts JA; Middleton R; Nicholas R; Bezlyak V; Adlard N; Hach T; Lines C; Glaser A
Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2021;28:665-666

Secondary Progressive MS treatment escalation identified algorithmically & clinically: A multi-registry based approach

Nicholas R; Witts J; Rodgers W; Forsberg L; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen HP; Magyari M; Ellenberger D; Stahmann A; VanDerWalt A; Lines C; Hach T; Hillert J; Middleton R
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):48-49

First results of the COVID-19 in ms global data sharing initiative suggest anti-CD20 dmts are associated with worse covid-19 outcomes

Simpson-Yap S; De Brouwer E; Kalincik T; Rijke N; Hillert J; Walton C; Edan G; Moreau Y; Spelman T; Geys L; Parciak T; Gautrais C; Lazovski N; Pirmani A; Ardeshirdavani A; Forsberg L; Glaser A; Mcburney R; Schmidt H; Bergmann A; Braune S; Stahmann A; Middleton R; Salter A; Van der Walt A; Rojas J; Van der Mei I; Ivanov R; Sciascia Do Olival G; Dias A; Magyari M; Brum D; Mendes MF; Alonso R; Nicholas R; Bauer J; Chertcoff A; Zabalza A; Arrambide G; Comi G; Peeters LM
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):320-321

Performance on symbol digits modalities test preceding conversion to secondary progressive multiple sclerosis

Karrenbauer VD; Forsberg L; Hillert J
Preprint: SSRN ELECTRONIC JOURNAL. 2020

Associations of DMT Therapies with COVID-19 Severity in Multiple Sclerosis: An International Cohort Study

Simpson-Yap S; De Brouwer E; Kalincik T; Rijke N; Hillert J; Walton C; Edan G; Moreau Y; Spelman T; Geys L; Parciak T; Gautrais C; Lazovski N; Pirmani A; Ardeshirdavani A; Forsberg L; Glaser A; McBurney R; Schmidt H; Bergmann A; Braune S; Stahmann A; Middleton R; Salter A; Fox RJ; Van Der Welt A; Butzkueven H; Rojas JI; van der Mei I; Nag N; Ivanov R; do Olival GS; Dias AE; Magyari M; Brum DG; Mendes MF; Alonso R; Nicholas R; Bauer J; Chertcoff A; Zabalza A; Arrambide G; Fidao A; Comi G; Peeters LM
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):348

Objective classification methods result in an increased proportion of secondary progressive multiple sclerosis in five patient registries

Glaser A; Forsberg L; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Magyari M; Ellenberger D; Stahmann A; Van der Walt A; Rodgers J; Middleton R; Nicholas R; Bezlyak V; Adlard N; Hach T; Lines C; Hillert J
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):11-12

Cortical atrophy in multiple sclerosis may start at puberty grey matter pathology

Stawiarz L; Granberg T; Manouchehrinia A; Hagel E; Hillert J; Forsberg L
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):20-21

Ongoing disease modifying treatment associated with mis-classification of secondary progressive as relapsing-emitting multiple sclerosis Pharmacological management of progressive MS

Hillert J; Forsberg L; Manouchehrinia A; Ramanujam R; Spelman T; Klyve P; Drahota J; Horakova D; Joensen H; Magyari M; Ellenberger D; Stahmann A; Van der Walt A; Rodgers J; Nicholas R; Middleton R; Bezlyak V; Adlard N; Hach T; Lines C; Glaser A
Conference publication: NEUROLOGY. 2020;94(15)

Comparison of the proportions of Secondary Progressive Multiple Sclerosis between three registries within the SPMS Research Collaboration Network

Forsberg L; Stahmann A; Middleton R; Ellenberger D; Rodgers J; Nicholas R; Ramanujam R; Manouchehrinia A; Pillai N; Dobay P; Lines C; Hach T; Glaser A; Hillert J
Conference publication: INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY. 2006;61(3):362-363

Motor control in left-handed subjects: A functional MR imaging study

Grabowska A; Gut M; Urbanik A; Forsberg L; Binder M; Sobiecka B; Kozub J
Conference publication: JOURNAL OF PSYCHOPHYSIOLOGY. 2006;20(4):323

The effect of left-handedness on lateralization of motor functions in the brain - fMRl study

Gut M; Grabowska A; Urbanik A; Forsberg L; Binder M; Sobiecka B; Kozub J
Published conference paper: BRAIN STRUCTURE & FUNCTION. 2005;210(5-6):407-410

Simulating activations with cytoarchitecture

Young JP; Forsberg LE
Preprint: NATURE PRECEDINGS.

1st INCF Workshop on NeuroImaging Database Integration

Forsberg L; Roland P
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Employments

Research Specialist, Department of Clinical Neuroscience, Karolinska Institutet, 2023-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of neuroscience, Karolinska Institutet, 2022
Master of Science, Physics Engineering, Royal Institute of Technology, 2005

About me

Articles

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