I work as a doctoral student at the Aging Research Center (ARC) at the Department of Neurobiology, Care Sciences and Society (NVS), under the main guidance of Associate Professor Hui-Xin Wang. My primary research interests are to better understand the relationship between work stress during working life and metabolic and cognitive health in later life.
Work is a relevant life activity and covers a long period of an individual’s life course. Exposure to work stress or job strain has been suggested to be associated with an increased risk of type 2 diabetes and could plausibly contribute to neural degeneration and cognitive impairment in later life by the activation of the hypothalamus-pituitary-adrenal (HPA) axis and the release of glucocorticoid hormone. Inflammatory and metabolic pathways are tightly linked and converge at several levels to maintain homeostasis. However, research examining the role of inflammatory and metabolic markers in the association between work stress, T2DM and cognitive dysfunction is limited. The ultimate goal of this doctoral project is to examine the role of work stress in later life metabolic and cognitive health and to explore the underlying biological mechanisms.