Kristoffer Månsson
Assistant Professor | Senior Research Specialist | Docent
E-mail: kristoffer.mansson@ki.se
Telephone: +46852482784
Visiting address: Nobels väg 9, D3, 17165 Solna
Postal address: K8 Klinisk neurovetenskap, K8 CPF Månsson, 171 77 Stockholm
Part of:
- Department of Clinical Neuroscience
- Centre for Psychiatry Research at CNS
- Neuroimage affective treatment and individual variability laboratory (NATIV Lab) – Kristoffer Månsson's research group
About me
- * Associate Professor (Docent), Karolinska Institutet
* Assistant Professor with research funding (100%) for 6 years, Karolinska
Institutet
* Senior Research Specialist, Karolinska Institutet (on leave)
* International postdoctoral fellow via the Swedish Research Council:
* Dartmouth College, Hanover, New Hampshire, US (2021-2022)
* Max Planck Institute for Human Development, Berlin Germany (2019-2021)
* Study director, Research school in clinical psychiatry, Karolinska
Institutet (2017-2020)
* Postdoctoral fellow, Stockholm University (2017-2019)
* PhD, Linköping University (2011-2016)
* Awarded the best scientific talk at the Alpine Brain Imaging Meeting,
Champéry, Switzerland, 2020
* Nominated (2018, Uppsala University; 2019, Karolinska Institutet) as an
outstanding young researcher in psychology to the Swedish National
Committee for Psychological Sciences.
* Awarded the Aaron T Beck student scholarship in 2013.
PhD (2016, Linköping University), Clinical psychology program (2011, Umeå
University; 2012, Lic Clinical Psychologist, Socialstyrelsen).
Research
- *Highlighted publication*
*Månsson, K. N. T.*, Waschke, L., Manzouri, A., Furmark, T., Fischer, H., &
Garrett, D. D. (2022). Moment-to-Moment Brain Signal Variability Reliably
Predicts Psychiatric Treatment Outcome. Biological Psychiatry, 91(7),
658–666. https://doi.org/10.1016/j.biopsych.2021.09.026 [1]
*Månsson, K. N. T.*, Cortes, D. S., Manzouri, A., Li, T.-Q., Hau, S., &
Fischer, H. (2020). Viewing Pictures Triggers Rapid Morphological Enlargement
in the Human Visual Cortex. Cerebral Cortex , 30(3),
851–857. https://doi.org/10.1093/cercor/bhz131 [2]
Olivo, G., Lövdén, M., Manzouri, A., Terlau, L., Jenner, B., Jafari, A.,
Petersson, S., Li, T.-Q., Fischer, H., & *Månsson, K. N. T. *(2022).
Estimated Gray Matter Volume Rapidly Changes after a Short Motor Task.
Cerebral Cortex. https://doi.org/10.1093/cercor/bhab488 [3]
*Månsson, K. N. T.*, Lasselin, J., Karshikoff, B., Axelsson, J., Engler, H.,
Schedlowski, M., Benson, S., Petrovic, P., & Lekander, M. (2022). Anterior
insula morphology and vulnerability to psychopathology-related symptoms in
response to acute inflammation. Brain, Behavior, and Immunity, 99,
9–16. https://doi.org/10.1016/j.bbi.2021.09.007 [4]
*Månsson, K. N. T.*, Lindqvist, D., Yang, L. L., Svanborg, C., Isung, J.,
Nilsonne, G., Bergman-Nordgren, L., El Alaoui, S., Hedman-Lagerlöf, E.,
Kraepelien, M., Högström, J., Andersson, G., Boraxbekk, C.-J., Fischer, H.,
Lavebratt, C., Wolkowitz, O. M., & Furmark, T. (2019). Improvement in indices
of cellular protection after psychological treatment for social anxiety
disorder. Translational Psychiatry, 9(1),
340. https://doi.org/10.1038/s41398-019-0668-2 [5]
*Månsson, K. N. T.*, Lueken, U., & Frick, A. (2021). Enriching CBT by
Neuroscience: Novel Avenues to Achieve Personalized Treatments. International
Journal of Cognitive Therapy, 14(1),
182–195. https://doi.org/10.1007/s41811-020-00089-0 [6]
[1] https://doi.org/10.1016/j.biopsych.2021.09.026
[2] https://doi.org/10.1093/cercor/bhz131
[3] https://doi.org/10.1093/cercor/bhab488
[4] https://doi.org/10.1016/j.bbi.2021.09.007
[5] https://doi.org/10.1038/s41398-019-0668-2
[6] https://doi.org/10.1007/s41811-020-00089-0
Teaching
- Study director for the research school in clinical psychiatry at the Center
for Psychiatry Research (2017-2020). Regularly teach methods in cognitive
behavior therapy for clinical psychologists.
Articles
- Article: BMC PSYCHIATRY. 2025;25(1):36Forsstrom D; Badinlou F; Johansson M; Ojala O; Alaoui SE; Mansson KNT; Rozental A; Lundin J; Jangard S; Shahnavaz S; Sorman K; Jayaram-Lindstrom N; Lundgren T; Jansson-Frojmark M; Hedman-Lagerlof M
- Article: COGNITIVE BEHAVIOUR THERAPY. 2025;54(1):78-95Garke MA; Isacsson NH; Kolbeinsson O; Hesser H; Mansson KNT
- Article: PLOS ONE. 2024;19(11):e0313961Ojala O; Garke MA; El Alaoui S; Forsstrom D; Hedman-Lagerlof M; Jangard S; Lundin J; Rozental A; Shahnavaz S; Sorman K; Lundgren T; Hellner C; Jayaram-Lindstrom N; Mansson KNT
- Article: CORTEX. 2024;175:1-11Laukka P; Mansson KNT; Cortes DS; Manzouri A; Frick A; Fredborg W; Fischer H
- Article: PSYCHONEUROENDOCRINOLOGY. 2024;160:106666Xiao S; Ebner NC; Manzouri A; Li T-Q; Cortes DS; Mansson KNT; Fischer H
- Journal article: NATURE MENTAL HEALTH. 2024;2(1):104-118Bruin WB; Zhutovsky P; van Wingen GA; Bas-Hoogendam JM; Groenewold NA; Hilbert K; Winkler AM; Zugman A; Agosta F; Ahs F; Andreescu C; Antonacci C; Asami T; Assaf M; Barber JP; Bauer J; Bavdekar SY; Beesdo-Baum K; Benedetti F; Bernstein R; Bjorkstrand J; Blair RJ; Blair KS; Blanco-Hinojo L; Bohnlein J; Brambilla P; Bressan RA; Breuer F; Cano M; Canu E; Cardinale EM; Cardoner N; Cividini C; Cremers H; Dannlowski U; Diefenbach GJ; Domschke K; Doruyter AGG; Dresler T; Erhardt A; Filippi M; Fonzo GA; Freitag GF; Furmark T; Ge T; Gerber AJ; Gosnell SN; Grabe HJ; Grotegerd D; Gur RC; Gur RE; Hamm AO; Han LKM; Harper JC; Harrewijn A; Heeren A; Hofmann D; Jackowski AP; Jahanshad N; Jett L; Kaczkurkin AN; Khosravi P; Kingsley EN; Kircher T; Kostic M; Larsen B; Lee S-H; Leehr EJ; Leibenluft E; Lochner C; Lui S; Maggioni E; Manfro GG; Mansson KNT; Marino CE; Meeten F; Milrod B; Jovanovic AM; Mwangi B; Myers MJ; Neufang S; Nielsen JA; Ohrmann PA; Ottaviani C; Paulus MP; Perino MT; Phan KL; Poletti S; Porta-Casteras D; Pujol J; Reinecke A; Ringlein GV; Rjabtsenkov P; Roelofs K; Salas R; Salum GA; Satterthwaite TD; Schrammen E; Sindermann L; Smoller JW; Soares JC; Stark R; Stein F; Straube T; Straube B; Strawn JR; Suarez-Jimenez B; Sylvester CM; Talati A; Thomopoulos SI; Tukel R; van Nieuwenhuizen H; Werwath K; Wittfeld K; Wright B; Wu M-J; Yang Y; Zilverstand A; Zwanzger P; Blackford JU; Avery SN; Clauss JA; Lueken U; Thompson PM; Pine DS; Stein DJ; van der Wee NJA; Veltman DJ; Aghajani M
- Article: BMJ OPEN. 2023;13(11):e076900Lindahl J; Asp M; Stahl D; Tjernberg J; Eklund M; Bjorkstrand J; van Westen D; Jensen J; Mansson K; Tornberg A; Svensson M; Deierborg T; Ventorp F; Lindqvist D
- Journal article: BRAIN BEHAVIOR AND IMMUNITY. 2023;114:51Lekander M; Hansson LS; Manzouri A; Tognetti A; Sigurjonsson P; Bruck E; Toll R; Wilhelms D; Petrovic P; Mansson K; Lasselin J
- Article: BEHAVIOURAL BRAIN RESEARCH. 2023;442:114304Wlad M; Frick A; Engman J; Hjorth O; Hoppe JM; Faria V; Wahlstedt K; Bjorkstrand J; Mansson KNT; Hultberg S; Alaie I; Rosen J; Fredrikson M; Furmark T; Gingnell M
- Article: MOLECULAR PSYCHIATRY. 2023;28(3):1079-1089Groenewold NA; Bas-Hoogendam JM; Amod AR; Laansma MA; Van Velzen LS; Aghajani M; Hilbert K; Oh H; Salas R; Jackowski AP; Pan PM; Salum GA; Blair JR; Blair KS; Hirsch J; Pantazatos SP; Schneier FR; Talati A; Roelofs K; Volman I; Blanco-Hinojo L; Cardoner N; Pujol J; Beesdo-Baum K; Ching CRK; Thomopoulos SI; Jansen A; Kircher T; Krug A; Nenadic I; Stein F; Dannlowski U; Grotegerd D; Lemke H; Meinert S; Winter A; Erb M; Kreifelts B; Gong Q; Lui S; Zhu F; Mwangi B; Soares JC; Wu M-J; Bayram A; Canli M; Tukel R; Westenberg PM; Heeren A; Cremers HR; Hofmann D; Straube T; Doruyter AGG; Lochner C; Peterburs J; Van Tol M-J; Gur RE; Kaczkurkin AN; Larsen B; Satterthwaite TD; Filippi CA; Gold AL; Harrewijn A; Zugman A; Buelow R; Grabe HJ; Voelzke H; Wittfeld K; Boehnlein J; Dohm K; Kugel H; Schrammen E; Zwanzger P; Leehr EJ; Sindermann L; Ball TM; Fonzo GA; Paulus MP; Simmons A; Stein MB; Klumpp H; Phan KL; Furmark T; Mansson KNT; Manzouri A; Avery SN; Blackford JU; Clauss JA; Feola B; Harper JC; Sylvester CM; Lueken U; Veltman DJ; Winkler AM; Jahanshad N; Pine DS; Thompson PM; Stein DJ; Van der Wee NJA
- Article: PSYCHONEUROENDOCRINOLOGY. 2023;148:106001Lindqvist D; Furmark T; Lavebratt C; Ohlsson L; Mansson KNT
- Article: FRONTIERS IN PSYCHOLOGY. 2022;13:1045709Forsstrom D; Lindner P; Mansson KNT; Ojala O; Hedman-Lagerlof M; El Alaoui S; Rozental A; Lundin J; Jangard S; Shahnavaz S; Sorman K; Lundgren T; Jayaram-Lindstrom N
- Article: CEREBRAL CORTEX. 2022;32(19):4356-4369Olivo G; Lovden M; Manzouri A; Terlau L; Jenner B; Jafari A; Petersson S; Li T-Q; Fischer H; Mansson KNT
- Article: FRONTIERS IN PSYCHIATRY. 2022;13:933858Rozental A; Soerman K; Ojala O; Jangard S; El Alaoui S; Mansson KNT; Shahnavaz S; Lundin J; Forsstroem D; Hedman-Lagerloef M; Lundgren T; Jayaram-Lindstroem N
- Journal article: BIOLOGICAL PSYCHIATRY. 2022;91(9):s140Månsson K; Waschke L; Manzouri A; Furmark T; Fischer H; Garrett DD
- Article: BIOLOGICAL PSYCHIATRY. 2022;91(7):658-666Mansson KNT; Waschke L; Manzouri A; Furmark T; Fischer H; Garrett DD
- Article: PLOS ONE. 2022;17(2):e0263173Kumar P; Stiernborg M; Fogdell-Hahn A; Mansson K; Furmark T; Berglind D; Melas PA; Forsell Y; Lavebratt C
- Article: BRAIN BEHAVIOR AND IMMUNITY. 2022;99:9-16Mansson KNT; Lasselin J; Karshikoff B; Axelsson J; Engler H; Schedlowski M; Benson S; Petrovic P; Lekander M
- Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):559Hjorth OR; Frick A; Gingnell M; Hoppe JM; Faria V; Hultberg S; Alaie I; Mansson KNT; Rosen J; Reis M; Wahlstedt K; Jonasson M; Lubberink M; Antoni G; Fredrikson M; Furmark T
- Article: FRONTIERS IN NEUROSCIENCE. 2021;15:768418Li X; Fischer H; Manzouri A; Mansson KNT; Li T-Q
- Article: DATA IN BRIEF. 2021;38:107333Li X; Fischer H; Manzouri A; Mansson KNT; Li T-Q
- Article: MOLECULAR PSYCHIATRY. 2021;26(8):3970-3979Hjorth OR; Frick A; Gingnell M; Hoppe JM; Faria V; Hultberg S; Alaie I; Mansson KNT; Wahlstedt K; Jonasson M; Lubberink M; Antoni G; Fredrikson M; Furmark T
- Article: PSYCHOPHYSIOLOGY. 2021;58(7):e13688Koenig J; Abler B; Agartz I; akerstedt T; Andreassen OA; Anthony M; Baer K-J; Bertsch K; Brown RC; Brunner R; Carnevali L; Critchley HD; Cullen KR; de Geus EJC; de la Cruz F; Dziobek I; Ferger MD; Fischer H; Flor H; Gaebler M; Gianaros PJ; Giummarra MJ; Greening SG; Guendelman S; Heathers JAJ; Herpertz SC; Hu MX; Jentschke S; Kaess M; Kaufmann T; Klimes-Dougan B; Koelsch S; Krauch M; Kumral D; Lamers F; Lee T-H; Lekander M; Lin F; Lotze M; Makovac E; Mancini M; Mancke F; Mansson KNT; Manuck SB; Mather M; Meeten F; Min J; Mueller B; Muench V; Nees F; Nga L; Nilsonne G; Ordonez Acuna D; Osnes B; Ottaviani C; Penninx BWJH; Ponzio A; Poudel GR; Reinelt J; Ren P; Sakaki M; Schumann A; Sorensen L; Specht K; Straub J; Tamm S; Thai M; Thayer JF; Ubani B; van Der Mee DJ; van Velzen LS; Ventura-Bort C; Villringer A; Watson DR; Wei L; Wendt J; Schreiner MW; Westlye LT; Weymar M; Winkelmann T; Wu G-R; Yoo HJ; Quintana DS
- Article: INTERNATIONAL JOURNAL OF COGNITIVE THERAPY. 2021;14(1):182-195Mansson KNT; Lueken U; Frick A
- Article: NATURE AND SCIENCE OF SLEEP. 2020;12:289-298Akerstedt T; Lekander M; Nilsonne G; Tamm S; d'Onofrio P; Kecklund G; Fischer H; Schwarz J; Petrovic P; Mansson KNT
- Article: PLOS ONE. 2020;15(4):e0232187Costache ME; Frick A; Mansson K; Engman J; Faria V; Hjorth O; Hoppe JM; Gingnell M; Frans O; Bjorkstrand J; Rosen J; Alaie I; Ahs F; Linnman C; Wahlstedt K; Tillfors M; Marteinsdottir I; Fredrikson M; Furmark T
- Article: JOURNAL OF PARKINSONS DISEASE. 2020;10(2):653-664Kraepelien M; Schibbye R; Mansson K; Sundstrom C; Riggare S; Andersson G; Lindefors N; Svenningsson P; Kaldo V
- Article: CEREBRAL CORTEX. 2020;30(3):851-857Mansson KNT; Cortes DS; Manzouri A; Li T-Q; Hau S; Fischer H
- Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):340Mansson KNT; Lindqvist D; Yang LL; Svanborg C; Isung J; Nilsonne G; Bergman-Nordgren L; El Alaoui S; Hedman-Lagerlof E; Kraepelien M; Hogstrom J; Andersson G; Boraxbekk C-J; Fischer H; Lavebratt C; Wolkowitz OM; Furmark T
- Article: BEHAVIOURAL AND COGNITIVE PSYCHOTHERAPY. 2019;47(5):559-572Rozental A; Kottorp A; Forsstrom D; Mansson K; Boettcher J; Andersson G; Furmark T; Carlbring P
- Article: PSYCHONEUROENDOCRINOLOGY. 2019;106:293-311Han LKM; Verhoeven JE; Tyrka AR; Penninx BWJH; Wolkowitz OM; Mansson KNT; Lindqvist D; Boks MP; Revesz D; Mellon SH; Picard M
- Article: JOURNAL OF CLINICAL PSYCHOLOGY. 2018;74(7):1092-1105Ivanov VZ; Enander J; Mataix-Cols D; Serlachius E; Mansson KNT; Andersson G; Flygare O; Tolin D; Ruck C
- Article: INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH. 2018;27(1)Lenhard F; Sauer S; Andersson E; Mansson KNT; Mataix-Cols D; Ruck C; Serlachius E
- Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2018;28(2):317-333Goodwin GM; Holmes EA; Andersson E; Browning M; Jones A; Lass-Hennemann J; Mansson KNT; Moessnang C; Salemink E; Sanchez A; van Zutphen L; Visser RM
- Article: EBIOMEDICINE. 2017;24:179-188Faria V; Gingnell M; Hoppe JM; Hjorth O; Alaie I; Frick A; Hultberg S; Wahlstedt K; Engman J; Mansson KNT; Carlbring P; Andersson G; Reis M; Larsson E-M; Fredrikson M; Furmark T
- Article: JMIR RESEARCH PROTOCOLS. 2017;6(8):e158Månsson KN; Klintmalm H; Nordqvist R; Andersson G
- Article: BEHAVIOURAL BRAIN RESEARCH. 2017;318:45-51Mansson KNT; Salami A; Carlbring P; Boraxbekk C-J; Andersson G; Furmark T
- Article: NEUROIMAGE-CLINICAL. 2017;16:678-688Bas-Hoogendam JM; van Steenbergen H; Pannekoek JN; Fouche J-P; Lochner C; Hattingh CJ; Cremers HR; Furmark T; Mansson KNT; Frick A; Engman J; Boraxbekk C-J; Carlbring P; Andersson G; Fredrikson M; Straube T; Peterburs J; Klumpp H; Phanp KL; Roelofs K; Veltman DJ; van Tol M-J; Stein DJ; van der Wee NJA
- Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2016;4:82-91Brännström KJ; Öberg M; Ingo E; Månsson KNT; Andersson G; Lunner T; Laplante-Lévesque A
- Article: TRANSLATIONAL PSYCHIATRY. 2016;6(2):e727Mansson KNT; Salami A; Frick A; Carlbring P; Andersson G; Furmark T; Boraxbekk C-J
- Article: AMERICAN JOURNAL OF AUDIOLOGY. 2015;24(3):320-324Brannstrom KJ; Oberg M; Ingo E; Mansson KNT; Andersson G; Lunner T; Laplante-Levesque A
- Article: PLOS ONE. 2015;10(5):e0123997Tulbure BT; Szentagotai A; David O; Stefan S; Mansson KNT; David D; Andersson G
- Article: TRANSLATIONAL PSYCHIATRY. 2015;5(3):e530Mansson KNT; Frick A; Boraxbekk C-J; Marquand AF; Williams SCR; Carlbring P; Andersson G; Furmark T
- Article: F1000RESEARCH. 2015;4:1073Nilsonne G; Tamm S; Månsson KNT; Åkerstedt T; Lekander M
- Article: PSYCHIATRY RESEARCH. 2013;214(3):229-237Mansson KNT; Carlbring P; Frick A; Engman J; Olsson C-J; Bodlund O; Furmark T; Andersson G
- Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2013;15(12):e280Mansson KNT; Ruiz ES; Gervind E; Dahlin M; Andersson G
- Article: TRIALS. 2012;13:202Tulbure BT; Mansson KNT; Andersson G
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All other publications
- Review: BIOLOGICAL PSYCHIATRY. 2025;98(3):195-207Tsikonofilos K; Kumar A; Ampatzis K; Garrett DD; Mansson KNT
- Review: BIOESSAYS. 2024;46(10):e2300246Verhoeven JE; Wolkowitz OM; Satz IB; Conklin Q; Lamers F; Lavebratt C; Lin J; Lindqvist D; Mayer SE; Melas PA; Milaneschi Y; Picard M; Rampersaud R; Rasgon N; Ridout K; Veiback GS; Trumpff C; Tyrka AR; Watson K; Wu GWY; Yang R; Zannas AS; Han LKM; Mansson KNT
- Preprint: BIORXIV. 2024Ntwatwa Z; Spreckelmeyer JM; Bas-Hoogendam JM; van Honk J; Mufford MM; Boraxbekk C-J; Fouche J-P; Frick A; Furmark T; Klumpp H; Lochner C; Phan KL; Månsson KNT; Pannekoek JN; Peterburs J; Roelofs K; Roos A; Straube T; van Steenbergen H; Van Tol M-J; Veltman DJ; van der Wee NJA; Stein DJ; Ipser JC; Groenewold NA
- Conference publication: BIOLOGICAL PSYCHIATRY. 2022;91(9):S140Mansson K; Waschke L; Manzouri A; Furmark T; Fischer H; Garrett DD
- Review: HUMAN BRAIN MAPPING. 2022;43(1):83-112Bas-Hoogendam JM; Groenewold NA; Aghajani M; Freitag GF; Harrewijn A; Hilbert K; Jahanshad N; Thomopoulos SI; Thompson PM; Veltman DJ; Winkler AM; Lueken U; Pine DS; van der Wee NJA; Stein DJ; ENIGMA-Anxiety Working Group
- Preprint: BIORXIV. 2021Frisk M; Kastrati G; Rosén J; Månsson KNT; Åhs F
- Preprint: MEDRXIV. 2021Månsson K; Waschke L; Manzouri A; Furmark T; Fischer H; Garrett D
- Preprint: BIORXIV. 2021Li X; Fischer H; Manzouri A; Månsson KNT; Li T-Q
- Conference publication: BIOLOGICAL PSYCHIATRY. 2020;87(9):S309Mansson K; Furmark T; Fischer H; Garrett D
- Conference publication: BIOLOGICAL PSYCHIATRY. 2020;87(9):S461-S462Mansson K; Cortes DS; Manzouri A; Li T-Q; Hau S; Fischer H
- Editorial comment: EBIOMEDICINE. 2018;36:5-6Frick A; Mansson KNT
- Preprint: BIORXIV. 2018Månsson KNT; Cortes DS; Manzouri A; Hau S; Fischer H
- Conference publication: JOURNAL OF SLEEP RESEARCH. 2018;27Akerstedt T; Lekander M; Nilsonne G; d'Onofrio P; Kecklund G; Fischer H; Schwarz J; Petrovic P; Mansson K
- Meeting abstract: BIOLOGICAL PSYCHIATRY. 2018;83(9):S351-S352Mansson K; Lindqvist D; Yang L; Wolkowitz O; Nilsonne G; Isung J; Svanborg C; Boraxbekk C-J; Fischer H; Lavebratt C; Furmark T
- Meeting abstract: BIOLOGICAL PSYCHIATRY. 2018;83(9):s249-s250Mansson K; Garrett D; Manzouri A; Wiegert S; Furmark T; Fischer H
- Meeting abstract: BIOLOGICAL PSYCHIATRY. 2018;83(9):s130-s131Mansson K; Wager TD; Isacsson N; Kolbeinsson O; Andersson G; Fischer H; Furmark T
- Conference publication: BIOLOGICAL PSYCHIATRY. 2018;83(9):S247-S248Groenewold N; Bas-Hoogendam JM; Amod AR; van Velzen L; Aghajani M; Filippi C; Gold A; Ching CRK; Roelofs K; Furmark T; Mansson K; Straube T; Peterburs J; Klumpp H; Phan KL; Lochner C; Doruyter A; Pujol J; Cardoner N; Blanco-Hinojo L; Beesdo-Baum K; Hilbert K; Kreifelts B; Erb M; Gong Q; Lui S; Soares J; Wu M-J; Westenberg PM; Grotegerd D; Leehr EJ; Dannlowski U; Zwanzger P; Veltman DJ; Pine DS; Jahanshad N; Thompson PM; Stein DJ; van der Wee NJA
- Meeting abstract: SLEEP. 2018;41:A58Akerstedt T; Lekander M; Nilsonne G; Tamm S; d'Onofrio P; Kecklund G; Fischer H; Petrovic P; Mansson KN
- Preprint: OSF PREPRINTS. 2018Koenig J; Abler B; Agartz I; Åkerstedt T; Andreassen OA; Anthony M; Bertsch K; Brown RC; Brunner R; Carnevali L; Critchley H; Cullen KR; de Geus EJC; Dziobek I; Fischer H; Flor H; Gaebler M; Gianaros PJ; Giummarra MJ; Greening SG; Guendelman S; Heathers J; Herpertz SC; Hu MX; Jentschke S; Kaess M; Kaufmann T; Klimes-Dougan B; Koelsch S; Krauch M; Kumral D; Lamers F; Lee T-H; Lekander M; Lin F; Lotze M; Makovac E; Mancini M; Mancke F; Månsson K; Manuck SN; Mather M; Meeten F; Min J; Mueller B; Muench V; Nees F; Nga L; Nilsonne G; Acuna DO; Osnes B; Ottaviani C; Penninx BWJH; Ponzio A; Poudel GR; Quintana DS; Reinelt J; Ren P; Sakaki M; Sørensen L; Specht K; Straub J; Tamm S; Thayer J; Ubani B; van der Mee DJ; van Velzen LS; Ventura-Bort C; Villringer A; Watson D; Wei L; Wendt J; Schreiner MW; Westlye LT; Weymar M; Winkelmann T; Wu G-R; Yoo HJ
- Meeting abstract: BIOLOGICAL PSYCHIATRY. 2017;81(10):s7-s8Bas-Hoogendam JM; van Steenbergen H; Pannekoek JN; Fouche J-P; Lochner C; Hattingh CJ; Cremers HR; Furmark T; Mansson KNT; Frick A; Engman J; Boraxbekk C-J; Carlbring P; Andersson G; Fredrikson M; Straube T; Peterburs J; Klumpp H; Phan KL; Roelofs K; Stein DJ; van der Wee NJA
- Book: LINKÖPING STUDIES IN BEHAVIOURAL SCIENCE. 2016Månsson KNT
- Conference publication: BIOLOGICAL PSYCHIATRY. 2015;77(9):51SMansson KN; Salami A; Frick A; Carlbring P; Furmark T; Olsson C-J; Andersson G
- Conference publication: BIOLOGICAL PSYCHIATRY. 2013;73(9):72SMansson KNT; Carlbring P; Frick A; Engman J; Olsson C-J; Bodlund O; Furmark T; Andersson G
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Selected grants
- Swedish Research Council1 January 2024 - 31 December 2027Internet-delivered cognitive behavior therapy (CBT) for social anxiety disorder is an evidence-based treatment in regular health care. Still, a considerable proportion of treated patients do not respond. There is also a debate on the importance of patients expectations’ for therapeutic outcomes. However, experimental evidence is lacking to answer this question. Our aim is thus to investigate the placebo response in social anxiety disorder, and the link between initial placebo responsiveness and subsequent outcome of CBT. First, we will manipulate expectations of anxiety relief. A benzodiazepine (a common anti-anxiety drug) will be administered with correct or incorrect information about clinical efficacy during a public speaking task. Self-reports and moment-to-moment variability in neural response will be measured with functional magnetic resonance imaging (fMRI) during the manipulation of expectations. The balanced placebo design allows us to dissect the total treatment effect into its components: drug, placebo, and interactions between the two. Second, patients undergo internet-delivered CBT after completing the placebo experiments. This project aims to unravel expectations´ influence on treatment response, and has a two-fold significance, 1) the scientific understanding of the neural mechanisms of treatment expectations, central for placebo, and 2) the development of pre-treatment predictors of CBT outcome which could improve precision in clinical decision making.
Grants
- Riksbankens Jubileumsfond1 January 2024 - 31 January 2026The question of how emotions are triggered remains obscure. A recent influential theory is built on predicting coding, which states that the brain makes predictions and constantly compares these predictions with the actual incoming sensory information. The active inference theory of emotions posits that emotions arise when there is a mismatch between the bodily (interoceptive) sensations and what was predicted by the brain, i.e. when interoceptive prediction errors occur. This theory is extremely relevant for emotional disorders linked with infections (e.g. post-COVID), since infections can trigger various and intense interoceptive signals that can be difficult to predict by the brain. In this project, we will apply the active inference theory of emotions in an ecologically relevant model of infection, using an innovative experimental approach. We will go beyond the existing correlational designs by applying a causal intervention eliciting real sickness symptoms, and manipulating interoceptive prediction errors directly, in 240 participants. We hypothesize that emotional responses will arise during sickness when interoceptive prediction errors occur, i.e. when interoceptive sensations violate predictions. This project will therefore provide critical information to understand how individuals' predictions shape sickness behavior, and how emotions are generated in infection-related conditions, which could open new therapies for mood disorders associated with immune activation.
- Bank of Sweden Tercentenary Foundation1 January 2024 - 31 December 2026The question of how emotions are triggered remains obscure. A recent influential theory is built on predicting coding, which states that the brain makes predictions and constantly compares these predictions with the actual incoming sensory information. The active inference theory of emotions posits that emotions arise when there is a mismatch between the bodily (interoceptive) sensations and what was predicted by the brain, i.e. when interoceptive prediction errors occur. This theory is extremely relevant for emotional disorders linked with infections (e.g. post-COVID), since infections can trigger various and intense interoceptive signals that can be difficult to predict by the brain. In this project, we will apply the active inference theory of emotions in an ecologically relevant model of infection, using an innovative experimental approach. We will go beyond the existing correlational designs by applying a causal intervention eliciting real sickness symptoms, and manipulating interoceptive prediction errors directly, in 240 participants. We hypothesize that emotional responses will arise during sickness when interoceptive prediction errors occur, i.e. when interoceptive sensations violate predictions. This project will therefore provide critical information to understand how individuals' predictions shape sickness behavior, and how emotions are generated in infection-related conditions, which could open new therapies for mood disorders associated with immune activation.
- Swedish Research Council1 January 2023 - 31 December 2026Socioemotional perception is of importance for social and emotional function in humans everyday life. Previous neuroimaging studies have investigated socioemotional perception (e.g. of facial expressions) at a group level ignoring the fact this is an individual phenomena. Precision neuroimaging (PI) focus on single subjects and many repeated trials. Using PI to study human brain function associated with socioemotional perception is an unexplored territory.In this four years neuroimaging project we will scan 8 subjects during 15 scanning sessions. During scanning subject will be exposed to blocks of dynamic visual, auditory and visual-auditory socioemotional stimuli varying in valence (positive-negative) and arousal (high-low). A multivariate within-subject approach will be used including functional and structural brain data, subjective responses and various physiological measures. All analyses are conducted at the individual level, meaning that statistical models are fit separately to data from each participant. Standard functional and structural MRI data analysis methods will be used in combination with explorative AI approaches for identifying correlations within and between patterns of brain connectivity and behavioral outcome measures.This as a proof-of-concept project in the forefront of a coming paradigm shift in cognitive neuroscience which will eventually open new scientific venues and making it possible to conduct parallel animal research to get at neural mechanisms.
- Swedish Research Council1 January 2022 - 31 December 2024
- Swedish Research Council1 January 2019 - 31 December 2021
- Swedish Research Council1 January 2018 - 31 December 2020
Employments
- Senior Research Specialist, Department of Clinical Neuroscience, Karolinska Institutet, 2022-
- Assistant Professor, Department of Clinical Neuroscience, Karolinska Institutet, 2022-2028
Degrees and Education
- Docent, Karolinska Institutet, 2022
Distinction and awards
- Honorable Mention from Biological Psychiatry's Somerfeld-Ziskind Research Award, For selection as a finalist for the 2023 Somerfeld-Ziskind Research Award., Society of Biological Psychiatry, 2023