Konstantinos Stamatopoulos

About me
Publications
Public outreach and news

About me

Visiting professor of Molecular Haematology

Articles

Article: LEUKEMIA. 2024;38(6):1287-1298
IκBε deficiency accelerates disease development in chronic lymphocytic leukemia
Bordini J; Lenzi C; Frenquelli M; Morabito A; Pseftogas A; Belloni D; Mansouri L; Tsiolas G; Perotta E; Ranghetti P; Gandini F; Genova F; Hagerstrand D; Gavriilidis G; Keisaris S; Pechlivanis N; Davi F; Kay NE; Langerak AW; Pospisilova S; Scarfo L; Makris A; Psomopoulos FE; Stamatopoulos K; Rosenquist R; Campanella A; Ghia P
Article: SEMINARS IN HEMATOLOGY. 2024;61(2):91-99
B-cell receptor immunoglobulin stereotypy in chronic lymphocytic leukemia: Key to understanding disease biology and stratifying patients
Agathangelidis A; Chatzikonstantinou T; Stamatopoulos K
Article: HAEMATOLOGICA. 2024;109(3):824-834
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia
Quinten E; Sepulveda-Yanez JH; Koning MT; Eken JA; Pfeifer D; Nteleah V; de Groen RAL; Saravia DA; Knijnenburg J; Stuivenberg-Bleijswijk HE; Pantic M; Agathangelidis A; Keppler-Hafkemeyer A; van Bergen CAM; Uribe-Paredes R; Stamatopoulos K; Vermaat JSP; Zirlik K; Navarrete MA; Jumaa H; Veelken H
Article: JOURNAL OF CLINICAL ONCOLOGY. 2024;42(4):452-466
Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes
Noerenberg D; Briest F; Hennch C; Yoshida K; Hablesreiter R; Takeuchi Y; Ueno H; Staiger AM; Ziepert M; Asmar F; Locher BN; Toth E; Weber T; Amini R-M; Klapper W; Bouzani M; Poeschel V; Rosenwald A; Held G; Campo E; Ishaque N; Stamatopoulos K; Kanellis G; Anagnostopoulos I; Bullinger L; Goldschmidt N; Zinzani PL; Boedoer C; Rosenquist R; Vassilakopoulos TP; Ott G; Ogawa S; Damm F
Article: JOURNAL OF IMMUNOLOGY. 2023;211(5):743-754
N-Glycosylation of the Ig Receptors Shapes the Antigen Reactivity in Chronic Lymphocytic Leukemia Subset #201
Iatrou A; Gounari M; Sofou E; Zaragoza-Infante L; Markopoulos I; Sarrigeorgiou I; Petrakis G; Pechlivanis N; Roumeliotou-Dimou M; Panayiotidis P; Stamatopoulos B; Gkanidou M; Sandaltzopoulos R; Degano M; Koletsa T; Lymberi P; Psomopoulos F; Ghia P; Agathangelidis A; Chatzidimitriou A; Stamatopoulos K
Article: BLOOD ADVANCES. 2023;7(12):2794-2806
BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib
Bonfiglio S; Sutton L-A; Ljungstrom V; Capasso A; Pandzic T; Westrom S; Foroughi-Asl H; Skaftason A; Gellerbring A; Lyander A; Gandini F; Gaidano G; Trentin L; Bonello L; Reda G; Bodor C; Stavroyianni N; Tam CS; Marasca R; Forconi F; Panayiotidis P; Ringshausen I; Jaksic O; Frustaci AM; Iyengar S; Coscia M; Mulligan SP; Ysebaert L; Strugov V; Pavlovsky C; Walewska R; Osterborg A; Cortese D; Ranghetti P; Baliakas P; Stamatopoulos K; Scarfo L; Rosenquist R; Ghia P
Article: LEUKEMIA. 2023;37(2):339-347
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylha C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larrayoz MJ; Calasanz MJ; Fesus V; Matrai Z; Bodor C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; N'Guyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Article: FRONTIERS IN ONCOLOGY. 2023;13:1123029
Differences in the immunoglobulin gene repertoires of IgG versus IgA multiple myeloma allude to distinct immunopathogenetic trajectories
Gkoliou G; Agathangelidis A; Karakatsoulis G; Lalayanni C; Papalexandri A; Medina A; Genuardi E; Chlichlia K; Hatjiharissi E; Papaioannou M; Terpos E; Jimenez C; Sakellari I; Ferrero S; Ladetto M; Sanz RG; Belessi C; Stamatopoulos K
Article: FRONTIERS IN ONCOLOGY. 2023;13:1097942
T cell receptor gene repertoire profiles in subgroups of patients with chronic lymphocytic leukemia bearing distinct genomic aberrations
Vlachonikola E; Pechlivanis N; Karakatsoulis G; Sofou E; Gkoliou G; Jeromin S; Stavroyianni N; Ranghetti P; Scarfo L; Osterholm C; Mansouri L; Notopoulou S; Siorenta A; Anagnostopoulos A; Ghia P; Haferlach C; Rosenquist R; Psomopoulos F; Kouvatsi A; Baliakas P; Stamatopoulos K; Chatzidimitriou A
Article: FRONTIERS IN MICROBIOLOGY. 2023;14:1292230
High risk HPV-positive women cervicovaginal microbial profiles in a Greek cohort: a retrospective analysis of the GRECOSELF study
Sofou E; Gkoliou G; Pechlivanis N; Pasentsis K; Chatzistamatiou K; Psomopoulos F; Agorastos T; Stamatopoulos K
Article: BRIEFINGS IN BIOINFORMATICS. 2022;23(5):bbac349
IgIDivA: immunoglobulin intraclonal diversification analysis
Zaragoza-Infante L; Junet V; Pechlivanis N; Fragkouli S-C; Amprachamian S; Koletsa T; Chatzidimitriou A; Papaioannou M; Stamatopoulos K; Agathangelidis A; Psomopoulos F
Article: SEMINARS IN CANCER BIOLOGY. 2022;84:170-183
Precision diagnostics in lymphomas-Recent developments and future directions
Mansouri L; Thorvaldsdottir B; Laidou S; Stamatopoulos K; Rosenquist R
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;198(1):103-113
Clonal haematopoiesis as a risk factor for therapy-related myeloid neoplasms in patients with chronic lymphocytic leukaemia treated with chemo-(immuno)therapy
Voso M-T; Pandzic T; Falconi G; Dencic-Fekete M; De Bellis E; Scarfo L; Ljungstrom V; Iskas M; Del Poeta G; Ranghetti P; Laidou S; Cristiano A; Plevova K; Imbergamo S; Engvall M; Zucchetto A; Salvetti C; Mauro FR; Stavroyianni N; Cavelier L; Ghia P; Stamatopoulos K; Fabiani E; Baliakas P
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2022;197(4):431-441
International validation of the EORTC QLQ-CLL17 questionnaire for assessment of health-related quality of life for patients with chronic lymphocytic leukaemia
Oerlemans S; Efficace F; Kieffer JM; Kyriakou C; Xochelli A; Levedahl K; Petranovic D; Borges FC; Bredart A; Shamieh O; Gziskevicius L; Lehmann J; Scholz CW; Caocci G; Molica S; Stamatopoulos K; Panteliadou A-K; Papaioannou M; Alrjoob W; Baliakas P; Rosenquist R; Malak S; Miranda A; Cocks K; van de Poll-Franse L
Article: HEMASPHERE. 2022;6(4):e707
Cytogenetics in Chronic Lymphocytic Leukemia: ERIC Perspectives and Recommendations
Baliakas P; Espinet B; Mellink C; Jarosova M; Athanasiadou A; Ghia P; Kater AP; Oscier D; Haferlach C; Stamatopoulos K
Article: METHODS IN MOLECULAR BIOLOGY. 2022;2453:585-603
Purpose-Built Immunoinformatics for BcR IG/TR Repertoire Data Analysis.
Galigalidou C; Zaragoza-Infante L; Chatzidimitriou A; Stamatopoulos K; Psomopoulos F; Agathangelidis A
Article: FRONTIERS IN ONCOLOGY. 2022;12:1079772
Evidence of somatic hypermutation in the antigen binding sites of patients with CLL harboring IGHV genes with 100% germline identity
Sofou E; Zaragoza-Infante L; Pechlivanis N; Karakatsoulis G; Notopoulou S; Stavroyianni N; Psomopoulos F; Georgiou E; de Septenville AL; Davi F; Agathangelidis A; Chatzidimitriou A; Stamatopoulos K
Article: FRONTIERS IN ONCOLOGY. 2022;12:897280
Impact of the Types and Relative Quantities of IGHV Gene Mutations in Predicting Prognosis of Patients With Chronic Lymphocytic Leukemia
Kaufman M; Yan X-J; Li W; Ghia EM; Langerak AW; Rassenti LZ; Belessi C; Kay NE; Davi F; Byrd JC; Pospisilova S; Brown JR; Catherwood M; Davis Z; Oscier D; Montillo M; Trentin L; Rosenquist R; Ghia P; Barrientos JC; Kolitz JE; Allen SL; Rai KR; Stamatopoulos K; Kipps TJ; Neuberg D; Chiorazzi N
Article: LEUKEMIA. 2021;35(12):3444-3454
COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study.
Chatzikonstantinou T; Kapetanakis A; Scarfò L; Karakatsoulis G; Allsup D; Cabrero AA; Andres M; Antic D; Baile M; Baliakas P; Bron D; Capasso A; Chatzileontiadou S; Cordoba R; Correa J-G; Cuéllar-García C; De Paoli L; De Paolis MR; Del Poeta G; Demosthenous C; Dimou M; Donaldson D; Doubek M; Efstathopoulou M; Eichhorst B; El-Ashwah S; Enrico A; Espinet B; Farina L; Ferrari A; Foglietta M; Frederiksen H; Fürstenau M; García-Marco JA; García-Serra R; Gentile M; Gimeno E; Glenthøj A; Gomes da Silva M; Gutwein O; Hakobyan YK; Herishanu Y; Hernández-Rivas JÁ; Herold T; Innocenti I; Itchaki G; Jaksic O; Janssens A; Kalashnikova ОB; Kalicińska E; Karlsson LK; Kater AP; Kersting S; Labrador J; Lad D; Laurenti L; Levin M-D; Lista E; Lopez-Garcia A; Malerba L; Marasca R; Marchetti M; Marquet J; Mattsson M; Mauro FR; Milosevic I; Mirás F; Morawska M; Motta M; Munir T; Murru R; Niemann CU; Rodrigues RN; Olivieri J; Orsucci L; Papaioannou M; Pavlovsky MA; Piskunova I; Popov VM; Quaglia FM; Quaresmini G; Qvist K; Reda G; Rigolin GM; Ruchlemer R; Saghumyan G; Shrestha A; Šimkovič M; Špaček M; Sportoletti P; Stanca O; Stavroyianni N; Tadmor T; Te Raa D; Tonino SH; Trentin L; Van Der Spek E; van Gelder M; van Kampen R; Varettoni M; Visentin A; Vitale C; Wasik-Szczepanek E; Wróbel T; San Segundo LY; Yassin M; Coscia M; Rambaldi A; Montserrat E; Foà R; Cuneo A; Stamatopoulos K; Ghia P
Article: BMJ OPEN. 2021;11(11):e050256
MyPal ADULT study protocol: a randomised clinical trial of the MyPal ePRO-based early palliative care system in adult patients with haematological malignancies
Scarfo L; Karamanidou C; Doubek M; Garani-Papadatos T; Didi J; Pontikoglou C; Ling J; Payne C; Papadaki HA; Rosenquist R; Stavroyianni N; Payne S; Ghia P; Natsiavas P; Maramis C; Stamatopoulos K
Article: LEUKEMIA. 2021;35(11):3163-3175
Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL
Ferrer G; Jung B; Chiu PY; Aslam R; Palacios F; Mazzarello AN; Vergani S; Bagnara D; Chen S-S; Yancopoulos S; Xochelli A; Yan X-J; Burger JA; Barrientos JC; Kolitz JE; Allen SL; Stamatopoulos K; Rai KR; Sherry B; Chiorazzi N
Article: BLOOD ADVANCES. 2021;5(16):3188-3198
Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders.
Stewart JP; Gazdova J; Darzentas N; Wren D; Proszek P; Fazio G; Songia S; Alcoceba M; Sarasquete ME; Villarese P; van der Klift MY; Heezen KC; McCafferty N; Pal K; Catherwood M; Kim CS; Srivastava S; Kroeze LI; Hodges E; Stamatopoulos K; Klapper W; Genuardi E; Ferrero S; van den Brand M; Cazzaniga G; Davi F; Sutton L-A; Garcia-Sanz R; Groenen PJTA; Macintyre EA; Brüggemann M; Pott C; Langerak AW; Gonzalez D; EuroClonality-NGS Working Group
Article: HEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA. 2021;35(4):687-702
The Significance of B-cell Receptor Stereotypy in Chronic Lymphocytic Leukemia: Biological and Clinical Implications.
Vlachonikola E; Sofou E; Chatzidimitriou A; Stamatopoulos K; Agathangelidis A
Article: BLOOD ADVANCES. 2021;5(13):2788-2792
RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia
Ntoufa S; Gerousi M; Laidou S; Psomopoulos F; Tsiolas G; Moysiadis T; Papakonstantinou N; Mansouri L; Anagnostopoulos A; Stavrogianni N; Pospisilova S; Plevova K; Makris AM; Rosenquist R; Stamatopoulos K
Article: BLOOD. 2021;137(14):1895-1904
Higher-order immunoglobulin repertoire restrictions in CLL: the illustrative case of stereotyped subsets 2 and 169
Gemenetzi K; Psomopoulos F; Carriles AA; Gounari M; Minici C; Plevova K; Sutton L-A; Tsagiopoulou M; Baliakas P; Pasentsis K; Anagnostopoulos A; Sandaltzopoulos R; Rosenquist R; Davi F; Pospisilova S; Ghia P; Stamatopoulos K; Degano M; Chatzidimitriou A
Article: BLOOD. 2021;137(10):1365-1376
Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL
Agathangelidis A; Chatzidimitriou A; Gemenetzi K; Giudicelli V; Karypidou M; Plevova K; Davis Z; Yan X-J; Jeromin S; Schneider C; Pedersen LB; Tschumper RC; Sutton L-A; Baliakas P; Scarfo L; van Gastel EJ; Armand M; Tausch E; Biderman B; Baer C; Bagnara D; Navarro A; de Septenville AL; Guido V; Mitterbauer-Hohendanner G; Dimovski A; Brieghel C; Lawless S; Meggendorfer M; Brazdilova K; Ritgen M; Facco M; Tresoldi C; Visentin A; Patriarca A; Catherwood M; Bonello L; Sudarikov A; Vanura K; Roumelioti M; Francova HS; Moysiadis T; Veronese S; Giannopoulos K; Mansouri L; Karan-Djurasevic T; Sandaltzopoulos R; Bodor C; Fais F; Kater A; Panovska I; Rossi D; Alshemmari S; Panagiotidis P; Costeas P; Espinet B; Antic D; Foroni L; Montillo M; Trentin L; Stavroyianni N; Gaidano G; di Celle PF; Niemann C; Campo E; Anagnostopoulos A; Pott C; Fischer K; Hallek M; Oscier D; Stilgenbauer S; Haferlach C; Jelinek D; Chiorazzi N; Pospisilova S; Lefranc M-P; Kossida S; Langerak AW; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: HAEMATOLOGICA. 2021;106(3):692-700
Stem cell factor is implicated in microenvironmental interactions and cellular dynamics of chronic lymphocytic leukemia
Gavriilidis GI; Ntoufa S; Papakostantinou N; Kotta K; Koletsa T; Chartomatsidou E; Moysiadis T; Stavroyianni N; Anagnostopoulos A; Papadaki E; Tsiftsoglou AS; Stamatopoulos K
Article: HAEMATOLOGICA. 2021;106(3):682-691
Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study
Sutton L-A; Ljungstrom V; Enjuanes A; Cortese D; Skaftason A; Tausch E; Kozubik KS; Nadeu F; Armand M; Malcikova J; Pandzic T; Forster J; Davis Z; Oscier D; Rossi D; Ghia P; Strefford JC; Pospisilova S; Stilgenbauer S; Davi F; Campo E; Stamatopoulos K; Rosenquist R
Article: CANCERS. 2021;13(2):285
The Calcitriol/Vitamin D Receptor System Regulates Key Immune Signaling Pathways in Chronic Lymphocytic Leukemia
Gerousi M; Psomopoulos F; Kotta K; Tsagiopoulou M; Stavroyianni N; Anagnostopoulos A; Anastasiadis A; Gkanidou M; Kotsianidis I; Ntoufa S; Stamatopoulos K
Article: HAEMATOLOGICA. 2021;106(1):87-97
Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: a multicenter study
Leeksma AC; Baliakas P; Moysiadis T; Puiggros A; Plevova K; van der Kevie-Kersemaekers A-M; Posthuma H; Rodriguez-Vicente AE; Tran AN; Barbany G; Mansouri L; Gunnarsson R; Parker H; van den Berg E; Bellido M; Davis Z; Wall M; Scarpelli I; Osterborg A; Hansson L; Jarosova M; Ghia P; Poddighe P; Espinet B; Pospisilova S; Tam C; Ysebaert L; Nguyen-Khac F; Oscier D; Haferlach C; Schoumans J; Stevens-Kroef M; Eldering E; Stamatopoulos K; Rosenquist R; Strefford JC; Mellink C; Kater AP
Article: HAEMATOLOGICA. 2020;105(11):2598-2607
Prognostic impact of prevalent chronic lymphocytic leukemia stereotyped subsets: analysis within prospective clinical trials of the German CLL Study Group
Jaramillo S; Agathangelidis A; Schneider C; Bahlo J; Robrecht S; Tausch E; Bloehdorn J; Hoechstetter M; Fischer K; Eichhorst B; Goede V; Hallek M; Doehner H; Rosenquist R; Ghia P; Stamatopoulos K; Stilgenbauer S
Article: JOURNAL OF WOMEN'S HEALTH. 2020;29(11):1447-1456
Acceptability of Self-Sampling for Human Papillomavirus-Based Cervical Cancer Screening
Chatzistamatiou K; Vrekoussis T; Tsertanidou A; Moysiadis T; Mouchtaropoulou E; Pasentsis K; Kitsou A; Moschaki V; Ntoula M; Zempili P; Halatsi D; Truva T; Piha V; Agelena G; Daponte A; Vanakara P; Paschopoulos M; Stefos T; Lymberis V; Kontomanolis EN; Makrigiannakis A; Deligeoroglou E; Panoskaltsis T; Adonakis G; Michail G; Stamatopoulos K; Agorastos T
Article: LEUKEMIA. 2020;34(10):2545-2551
Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
Davi F; Langerak AW; de Septenville AL; Kolijn PM; Hengeveld PJ; Chatzidimitriou A; Bonfiglio S; Sutton L-A; Rosenquist R; Ghia P; Stamatopoulos K
Article: BMC BIOINFORMATICS. 2020;21(1):422
TRIP - T cell receptor/immunoglobulin profiler
Kotouza MT; Gemenetzi K; Galigalidou C; Vlachonikola E; Pechlivanis N; Agathangelidis A; Sandaltzopoulos R; Mitkas PA; Stamatopoulos K; Chatzidimitriou A; Psomopoulos FE
Article: CLINICAL CANCER RESEARCH. 2020;26(18):4958-4969
T-Cell Dynamics in Chronic Lymphocytic Leukemia under Different Treatment Modalities
Vardi A; Vlachonikola E; Papazoglou D; Psomopoulos F; Kotta K; Ioannou N; Galigalidou C; Gemenetzi K; Pasentsis K; Kotouza M; Koravou E; Scarfo L; Iskas M; Stavroyianni N; Ghia P; Anagnostopoulos A; Kouvatsi A; Ramsay AG; Stamatopoulos K; Chatzidimitriou A
Article: CLINICAL EPIGENETICS. 2019;11(1):177
DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy
Tsagiopoulou M; Papakonstantinou N; Moysiadis T; Mansouri L; Ljungstrom V; Duran-Ferrer M; Malousi A; Queiros AC; Plevova K; Bhoi S; Kollia P; Oscier D; Anagnostopoulos A; Trentin L; Ritgen M; Pospisilova S; Stavroyianni N; Ghia P; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2019;14(11):1125-1140
EZH2 upregulates the PI3K/AKT pathway through IGF1R and MYC in clinically aggressive chronic lymphocytic leukaemia
Kosalai ST; Morsy MHA; Papakonstantinou N; Mansouri L; Stavroyianni N; Kanduri C; Stamatopoulos K; Rosenquist R; Kanduri M
Article: CANCER PREVENTION RESEARCH. 2019;12(10):701-710
Implementation of HPV-based Cervical Cancer Screening Combined with Self-sampling Using a Midwifery Network Across Rural Greece: The GRECOSELF Study
Agorastos T; Chatzistamatiou K; Tsertanidou A; Mouchtaropoulou E; Pasentsis K; Kitsou A; Moysiadis T; Moschaki V; Skenderi A; Katsiki E; Aggelidou S; Venizelos I; Ntoula M; Daponte A; Vanakara P; Garas A; Stefos T; Vrekoussis T; Lymberis V; Kontomanolis EN; Makrigiannakis A; Manidakis G; Deligeoroglou E; Panoskaltsis T; Decavalas GO; Michail G; Kalogiannidis I; Koukoulis G; Zempili P; Halatsi D; Truva T; Piha V; Agelena G; Chronopoulou A; Vaitsi V; Chatzaki E; Paschopoulos M; Adonakis G; Kaufmann AM; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD ADVANCES. 2019;3(12):1891-1896
Inhibition of EZH2 and immune signaling exerts synergistic antitumor effects in chronic lymphocytic leukemia
Chartomatsidou E; Ntoufa S; Kotta K; Rovida A; Akritidou MA; Belloni D; Ferrero E; Trangas T; Stavroyianni N; Anagnostopoulos A; Rosenquist R; Ghia P; Papakonstantinou N; Stamatopoulos K
Article: INTERNATIONAL JOURNAL OF CANCER. 2019;144(11):2695-2706
Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia
Papakonstantinou N; Ntoufa S; Tsagiopoulou M; Moysiadis T; Bhoi S; Malousi A; Psomopoulos F; Mansouri L; Laidou S; Papazoglou D; Gounari M; Pasentsis K; Plevova K; Kuci-Emruli V; Duran-Ferrer M; Davis Z; Ek S; Rossi D; Gaidano G; Ritgen M; Oscier D; Stavroyianni N; Pospisilova S; Davi F; Ghia P; Hadzidimitriou A; Belessi C; Martin-Subero JI; Pott C; Rosenquist R; Stamatopoulos K
Article: JOURNAL OF PATHOLOGY. 2019;247(4):416-421
Disease-biased and shared characteristics of the immunoglobulin gene repertoires in marginal zone B cell lymphoproliferations
Xochelli A; Bikos V; Polychronidou E; Galigalidou C; Agathangelidis A; Charlotte F; Moschonas P; Davis Z; Colombo M; Roumelioti M; Sutton L-A; Groenen P; van den Brand M; Boudjoghra M; Algara P; Traverse-Glehen A; Ferrer A; Stalika E; Karypidou M; Kanellis G; Kalpadakis C; Mollejo M; Pangalis G; Vlamos P; Amini R-M; Pospisilova S; Gonzalez D; Ponzoni M; Anagnostopoulos A; Giudicelli V; Lefranc M-P; Espinet B; Panagiotidis P; Piris MA; Du M-Q; Rosenquist R; Papadaki T; Belessi C; Ferrarini M; Oscier D; Tzovaras D; Ghia P; Davi F; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD. 2019;133(11):1205-1216
Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact.
Baliakas P; Jeromin S; Iskas M; Puiggros A; Plevova K; Nguyen-Khac F; Davis Z; Rigolin GM; Visentin A; Xochelli A; Delgado J; Baran-Marszak F; Stalika E; Abrisqueta P; Durechova K; Papaioannou G; Eclache V; Dimou M; Iliakis T; Collado R; Doubek M; Calasanz MJ; Ruiz-Xiville N; Moreno C; Jarosova M; Leeksma AC; Panayiotidis P; Podgornik H; Cymbalista F; Anagnostopoulos A; Trentin L; Stavroyianni N; Davi F; Ghia P; Kater AP; Cuneo A; Pospisilova S; Espinet B; Athanasiadou A; Oscier D; Haferlach C; Stamatopoulos K; ERIC, the European Research Initiative on CLL
Article: HAEMATOLOGICA. 2019;104(2):360-369
Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia
Baliakas P; Moysiadis T; Hadzidimitriou A; Xochelli A; Jeromin S; Agathangelidis A; Mattsson M; Sutton L-A; Minga E; Scarfo L; Rossi D; Davis Z; Villamor N; Parker H; Kotaskova J; Stalika E; Plevova K; Mansouri L; Cortese D; Navarro A; Delgado J; Larrayoz M; Young E; Anagnostopoulos A; Smedby KE; Juliusson G; Sheehy O; Catherwood M; Strefford JC; Stavroyianni N; Belessi C; Pospisilova S; Oscier D; Gaidano G; Campo E; Haferlach C; Ghia P; Rosenquist R; Stamatopoulos K
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1881:355-363
High-Throughput Sequencing of the T-Cell Receptor Beta Chain Gene Repertoire in Chronic Lymphocytic Leukemia.
Vlachonikola E; Vardi A; Stamatopoulos K; Hadzidimitriou A
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1881:51-62
Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.
Agathangelidis A; Rosenquist R; Davi F; Ghia P; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: JOURNAL OF VISUALIZED EXPERIMENTS. 2018;(141)
Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation
Agathangelidis A; Sutton LA; Hadzidimitriou A; Tresoldi C; Langerak AW; Belessi C; Davi F; Rosenquist R; Stamatopoulos K; Ghia P
Article: BMC BIOINFORMATICS. 2018;19(Suppl 14):414
Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia
Polychronidou E; Kalamaras I; Agathangelidis A; Sutton L-A; Yan X-J; Bikos V; Vardi A; Mochament K; Chiorazzi N; Belessi C; Rosenquist R; Ghia P; Stamatopoulos K; Vlamos P; Chailyan A; Overby N; Marcatili P; Hatzidimitriou A; Tzovaras D
Article: ONCOTARGET. 2018;9(40):26019-26031
A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.
Primo D; Scarfò L; Xochelli A; Mattsson M; Ranghetti P; Espinosa AB; Robles A; Gorrochategui J; Martínez-López J; de la Serna J; González M; Gil AC; Anguita E; Iraheta S; Munugalavadla V; Quéva C; Tannheimer S; Rosenquist R; Stamatopoulos K; Ballesteros J; Ghia P
Article: HAEMATOLOGICA. 2018;103(5):865-873
Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
Agathangelidis A; Ljungstrom V; Scarfo L; Fazi C; Gounari M; Pandzic T; Sutton L-A; Stamatopoulos K; Tonon G; Rosenquist R; Ghia P
Article: LEUKEMIA AND LYMPHOMA. 2017;58(12):2926-2933
Cytotoxic T cells in chronic idiopathic neutropenia express restricted antigen receptors.
Mastrodemou S; Stalika E; Vardi A; Gemenetzi K; Spanoudakis M; Karypidou M; Mavroudi I; Hadzidimitriou A; Stavropoulos-Giokas C; Papadaki HA; Stamatopoulos K
Article: LEUKEMIA AND LYMPHOMA. 2017;58(10):2419-2425
The inhibitory receptor toll interleukin-1R 8 (TIR8/IL-1R8/SIGIRR) is downregulated in chronic lymphocytic leukemia.
Vilia MG; Fonte E; Veliz Rodriguez T; Tocchetti M; Ranghetti P; Scarfò L; Papakonstantinou N; Ntoufa S; Stamatopoulos K; Ghia P; Muzio M
Article: CLINICAL CANCER RESEARCH. 2017;23(17):5292-5301
Chronic Lymphocytic Leukemia with Mutated IGHV4-34 Receptors: Shared and Distinct Immunogenetic Features and Clinical Outcomes
Xochelli A; Baliakas P; Kavakiotis I; Agathangelidis A; Sutton L-A; Minga E; Ntoufa S; Tausch E; Yan X-J; Shanafelt T; Plevova K; Boudjogra M; Rossi D; Davis Z; Navarro A; Sandberg Y; Vojdeman FJ; Scarfo L; Stavroyianni N; Sudarikov A; Veronese S; Tzenou T; Karan-Djurasevic T; Catherwood M; Kienle D; Chatzouli M; Facco M; Bahlo J; Pott C; Pedersen LB; Mansouri L; Smedby KE; Chu CC; Giudicelli V; Lefranc M-P; Panagiotidis P; Juliusson G; Anagnostopoulos A; Vlahavas I; Antic D; Trentin L; Montillo M; Niemann C; Doehner H; Langerak AW; Pospisilova S; Hallek M; Campo E; Chiorazzi N; Maglaveras N; Oscier D; Gaidano G; Jelinek DF; Stilgenbauer S; Chouvarda I; Darzentas N; Belessi C; Davi F; Hadzidimitriou A; Rosenquist R; Ghia P; Stamatopoulos K
Article: LEUKEMIA. 2017;31(7):1555-1561
Restrictions in the T-cell repertoire of chronic lymphocytic leukemia: high-throughput immunoprofiling supports selection by shared antigenic elements.
Vardi A; Vlachonikola E; Karypidou M; Stalika E; Bikos V; Gemenetzi K; Maramis C; Siorenta A; Anagnostopoulos A; Pospisilova S; Maglaveras N; Chouvarda I; Stamatopoulos K; Hadzidimitriou A
Article: LEUKEMIA. 2017;31(7):1547-1554
EGR2 mutations define a new clinically aggressive subgroup of chronic lymphocytic leukemia
Young E; Noerenberg D; Mansouri L; Ljungstrom V; Frick M; Sutton L-A; Blakemore SJ; Galan-Sousa J; Plevova K; Baliakas P; Rossi D; Clifford R; Roos-Weil D; Navrkalova V; Doerken B; Schmitt CA; Smedby KE; Juliusson G; Giacopelli B; Blachly JS; Belessi C; Panagiotidis P; Chiorazzi N; Davi F; Langerak AW; Oscier D; Schuh A; Gaidano G; Ghia P; Xu W; Fan L; Bernard OA; Nguyen-Khac F; Rassenti L; Li J; Kipps TJ; Stamatopoulos K; Pospisilova S; Zenz T; Oakes CC; Strefford JC; Rosenquist R; Damm F
Article: THE LANCET HAEMATOLOGY. 2017;4(7):e334-e340
Monoclonal B-cell lymphocytosis in a hospital-based UK population and a rural Ugandan population: a cross-sectional study
Rawstron AC; Ssemaganda A; de Tute R; Doughty C; Newton D; Vardi A; Evans PAS; Stamatopoulos K; Owen RG; Lightfoot T; Wakeham K; Karabarinde A; Asiki G; Newton R
Article: AMERICAN JOURNAL OF PATHOLOGY. 2017;187(7):1454-1458
Numerous Ontogenetic Roads to Mantle Cell Lymphoma Immunogenetic and Immunohistochemical Evidence
Pouliou E; Xochelli A; Kanellis G; Stalika E; Sutton L-A; Navarro A; Agathangelidis A; Dimosthenous K; Anagnostopoulos A; Patsouris E; Korkolopoulou P; Sundstrom C; Ghia P; Ponzoni M; Sander B; Campo E; Rosenquist R; Hadzidimitriou A; Stamatopoulos K; Papadaki T
Article: NATURE COMMUNICATIONS. 2017;8:15746
Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia.
Minici C; Gounari M; Übelhart R; Scarfò L; Dühren-von Minden M; Schneider D; Tasdogan A; Alkhatib A; Agathangelidis A; Ntoufa S; Chiorazzi N; Jumaa H; Stamatopoulos K; Ghia P; Degano M
Article: BEST PRACTICE AND RESEARCH: CLINICAL HAEMATOLOGY. 2017;30(1-2):77-83
Clonal B-cell lymphocytosis of marginal zone origin.
Xochelli A; Oscier D; Stamatopoulos K
Article: BLOOD. 2016;128(23):2666-2670
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
Mansouri L; Noerenberg D; Young E; Mylonas E; Abdulla M; Frick M; Asmar F; Ljungstroem V; Schneider M; Yoshida K; Skaftason A; Pandzic T; Gonzalez B; Tasidou A; Waldhueter N; Rivas-Delgado A; Angelopoulou M; Ziepert M; Arends CM; Couronne L; Lenze D; Baldus CD; Bastard C; Okosun J; Fitzgibbon J; Doerken B; Drexler HG; Roos-Weil D; Schmitt CA; Munch-Petersen HD; Zenz T; Hansmann M-L; Strefford JC; Enblad G; Bernard OA; Ralfkiaer E; Erlanson M; Korkolopoulou P; Hultdin M; Papadaki T; Gronbaek K; Lopez-Guillermo A; Ogawa S; Kuppers R; Stamatopoulos K; Stavroyianni N; Kanellis G; Rosenwald A; Campo E; Amini R-M; Ott G; Vassilakopoulos TP; Hummel M; Rosenquist R; Damm F
Article: ONCOTARGET. 2016;7(49):80916-80924
Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations.
Blanco G; Puiggros A; Baliakas P; Athanasiadou A; García-Malo M; Collado R; Xochelli A; Rodríguez-Rivera M; Ortega M; Calasanz MJ; Luño E; Vargas M; Grau J; Martínez-Laperche C; Valiente A; Cervera J; Anagnostopoulos A; Gimeno E; Abella E; Stalika E; Hernández-Rivas JM; Ortuño FJ; Robles D; Ferrer A; Ivars D; González M; Bosch F; Abrisqueta P; Stamatopoulos K; Espinet B
Article: LEUKEMIA. 2016;30(11):2179-2186
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia
Parker H; Rose-Zerilli MJJ; Larrayoz M; Clifford R; Edelmann J; Blakemore S; Gibson J; Wang J; Ljungstrom V; Wojdacz TK; Chaplin T; Roghanian A; Davis Z; Parker A; Tausch E; Ntoufa S; Ramos S; Robbe P; Alsolami R; Steele AJ; Packham G; Rodriguez-Vicente AE; Brown L; McNicholl F; Forconi F; Pettitt A; Hillmen P; Dyer M; Cragg MS; Chelala C; Oakes CC; Rosenquist R; Stamatopoulos K; Stilgenbauer S; Knight S; Schuh A; Oscier DG; Strefford JC
Article: HAEMATOLOGICA. 2016;101(8):959-967
Different spectra of recurrent gene mutations in subsets of chronic lymphocytic leukemia harboring stereotyped B-cell receptors
Sutton L-A; Young E; Baliakas P; Hadzidimitriou A; Moysiadis T; Plevova K; Rossi D; Kminkova J; Stalika E; Pedersen LB; Malcikova J; Agathangelidis A; Davis Z; Mansouri L; Scarfo L; Boudjoghra M; Navarro A; Muggen AF; Yan X-J; Nguyen-Khac F; Larrayoz M; Panagiotidis P; Chiorazzi N; Niemann CU; Belessi C; Campo E; Strefford JC; Langerak AW; Oscier D; Gaidano G; Pospisilova S; Davi F; Ghia P; Stamatopoulos K; Rosenquist R
Article: ONCOTARGET. 2016;7(24):35946-35959
The histone methyltransferase EZH2 as a novel prosurvival factor in clinically aggressive chronic lymphocytic leukemia
Papakonstantinou N; Ntoufa S; Chartomatsidou E; Kotta K; Agathangelidis A; Giassafaki L; Karamanli T; Bele P; Moysiadis T; Baliakas P; Sutton LA; Stavroyianni N; Anagnostopoulos A; Makris AM; Ghia P; Rosenquist R; Stamatopoulos K
Article: JOURNAL OF IMMUNOLOGY. 2016;196(10):4410-4417
B Cell Anergy Modulated by TLR1/2 and the miR-17∼92 Cluster Underlies the Indolent Clinical Course of Chronic Lymphocytic Leukemia Stereotyped Subset #4.
Ntoufa S; Papakonstantinou N; Apollonio B; Gounari M; Galigalidou C; Fonte E; Anagnostopoulos A; Belessi C; Muzio M; Ghia P; Stamatopoulos K
Article: CLINICAL CANCER RESEARCH. 2016;22(8):2032-2040
An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-2*04 Receptors
Bikos V; Karypidou M; Stalika E; Baliakas P; Xochelli A; Sutton L-A; Papadopoulos G; Agathangelidis A; Papadopoulou E; Davis Z; Algara P; Kanellis G; Traverse-Glehen A; Mollejo M; Anagnostopoulos A; Ponzoni M; Gonzalez D; Pospisilova S; Matutes E; Angel Piris M; Papadaki T; Ghia P; Rosenquist R; Oscier D; Darzentas N; Tzovaras D; Belessi C; Hadzidimitriou A; Stamatopoulos K
Article: BLOOD. 2016;127(8):1007-1016
Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations
Ljungstrom V; Cortese D; Young E; Pandzic T; Mansouri L; Plevova K; Ntoufa S; Baliakas P; Clifford R; Sutton L-A; Blakemore SJ; Stavroyianni N; Agathangelidis A; Rossi D; Hoglund M; Kotaskova J; Juliusson G; Belessi C; Chiorazzi N; Panagiotidis P; Langerak AW; Smedby KE; Oscier D; Gaidano G; Schuh A; Davi F; Pott C; Strefford JC; Trentin L; Pospisilova S; Ghia P; Stamatopoulos K; Sjoblom T; Rosenquist R
Article: HAEMATOLOGICA. 2016;101(2):115-208
The European Hematology Association Roadmap for European Hematology Research: a consensus document
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Article: CLINICAL CANCER RESEARCH. 2016;22(1):167-174
Antigen Selection Shapes the T-cell Repertoire in Chronic Lymphocytic Leukemia
Vardi A; Agathangelidis A; Stalika E; Karypidou M; Siorenta A; Anagnostopoulos A; Rosenquist R; Hadzidimitriou A; Ghia P; Sutton L-A; Stamatopoulos K
Article: BIOINFORMATICS. 2015;31(23):3844-3846
ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy.
Bystry V; Agathangelidis A; Bikos V; Sutton LA; Baliakas P; Hadzidimitriou A; Stamatopoulos K; Darzentas N; European Research Initiative on CLL
Article: CLINICAL CANCER RESEARCH. 2015;21(18):4174-4183
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing
Parry M; Rose-Zerilli MJJ; Ljungstrom V; Gibson J; Wang J; Walewska R; Parker H; Parker A; Davis Z; Gardiner A; McIver-Brown N; Kalpadakis C; Xochelli A; Anagnostopoulos A; Fazi C; de Castro DG; Dearden C; Pratt G; Rosenquist R; Ashton-Key M; Forconi F; Collins A; Ghia P; Matutes E; Pangalis G; Stamatopoulos K; Oscier D; Strefford JC
Article: BLOOD. 2015;125(23):3580-3587
Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8.
Gounari M; Ntoufa S; Apollonio B; Papakonstantinou N; Ponzoni M; Chu CC; Rossi D; Gaidano G; Chiorazzi N; Stamatopoulos K; Ghia P
Article: AMERICAN JOURNAL OF PATHOLOGY. 2015;185(6):1740-1748
Molecular Evidence for Antigen Drive in the Natural History of Mantle Cell Lymphoma
Xochelli A; Sutton L-A; Agathangelidis A; Stalika E; Karypidou M; Marantidou F; Navarro Lopez A; Papadopoulos G; Supikova J; Groenen P; Boudjogra M; Sundstrom C; Ponzoni M; Francova HS; Anagnostopoulos A; Pospisilova S; Papadaki T; Tzovaras D; Ghia P; Pott C; Davi F; Campo E; Rosenquist R; Hadzidimitriou A; Belessi C; Stamatopoulos K
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2015;212(6):833-843
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
Mansouri L; Sutton L-A; Ljungstrom V; Bondza S; Arngarden L; Bhoi S; Larsson J; Cortese D; Kalushkova A; Plevova K; Young E; Gunnarsson R; Falk-Sorqvist E; Lonn P; Muggen AF; Yan X-J; Sander B; Enblad G; Smedby KE; Juliusson G; Belessi C; Rung J; Chiorazzi N; Strefford JC; Langerak AW; Pospisilova S; Davi F; Hellstrom M; Jernberg-Wiklund H; Ghia P; Soderberg O; Stamatopoulos K; Nilsson M; Rosenquist R
Article: MOLECULAR MEDICINE. 2015;20(1):720-728
An Entity Evolving into a Community: Defining the Common Ancestor and Evolutionary Trajectory of Chronic Lymphocytic Leukemia Stereotyped Subset #4
Sutton L-A; Papadopoulos G; Hadzidimitriou A; Papadopoulos S; Kostareli E; Rosenquist R; Tzovaras D; Stamatopoulos K
Article: HAEMATOLOGICA. 2015;100(4):514-519
Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a Phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia
Moreno C; Montillo M; Panayiotidis P; Dimou M; Bloor A; Dupuis J; Schuh A; Norin S; Geisler C; Hillmen P; Doubek M; Trneny M; Obrtlikova P; Laurenti L; Stilgenbauer S; Smolej L; Ghia P; Cymbalista F; Jaeger U; Stamatopoulos K; Stavroyianni N; Carrington P; Zouabi H; Leblond V; Gomez-Garcia JC; Rubio M; Marasca R; Musuraca G; Rigacci L; Farina L; Paolini R; Pospisilova S; Kimby E; Bradley C; Montserrat E
Article: HAEMATOLOGICA. 2015;100(3):370-376
Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting
Sutton L-A; Ljungstrom V; Mansouri L; Young E; Cortese D; Navrkalova V; Malcikova J; Muggen AF; Trbusek M; Panagiotidis P; Davi F; Belessi C; Langerak AW; Ghia P; Pospisilova S; Stamatopoulos K; Rosenquist R
Article: LEUKEMIA. 2015;29(2):329-336
Recurrent mutations refine prognosis in chronic lymphocytic leukemia
Baliakas P; Hadzidimitriou A; Sutton L-A; Rossi D; Minga E; Villamor N; Larrayoz M; Kminkova J; Agathangelidis A; Davis Z; Tausch E; Stalika E; Kantorova B; Mansouri L; Scarfo L; Cortese D; Navrkalova V; Rose-Zerilli MJJ; Smedby KE; Juliusson G; Anagnostopoulos A; Makris AM; Navarro A; Delgado J; Oscier D; Belessi C; Stilgenbauer S; Ghia P; Pospisilova S; Gaidano G; Campo E; Strefford JC; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2015;125(5):856-859
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations
Baliakas P; Agathangelidis A; Hadzidimitriou A; Sutton L-A; Minga E; Tsanousa A; Scarfo L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; Moreno D; Van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Article: IMMUNOGENETICS. 2015;67(1):61-66
Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia
Xochelli A; Agathangelidis A; Kavakiotis I; Minga E; Sutton LA; Baliakas P; Chouvarda I; Giudicelli V; Vlahavas I; Maglaveras N; Bonello L; Trentin L; Tedeschi A; Panagiotidis P; Geisler C; Langerak AW; Pospisilova S; Jelinek DF; Oscier D; Chiorazzi N; Darzentas N; Davi F; Ghia P; Rosenquist R; Hadzidimitriou A; Belessi C; Lefranc M-P; Stamatopoulos K
Article: HAEMATOLOGICA. 2014;99(11):1722-1730
Silenced B-cell receptor response to autoantigen in a poor-prognostic subset of chronic lymphocytic leukemia
Bergh A-C; Evaldsson C; Pedersen LB; Geisler C; Stamatopoulos K; Rosenquist R; Rosen A
Article: THE LANCET HAEMATOLOGY. 2014;1(2):E74-E84
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study
Baliakas P; Hadzidimitriou A; Sutton L-A; Minga E; Agathangelidis A; Nichelatti M; Tsanousa A; Scarfo L; Davis Z; Yan X-J; Shanafelt T; Plevova K; Sandberg Y; Vojdeman FJ; Boudjogra M; Tzenou T; Chatzouli M; Chu CC; Veronese S; Gardiner A; Mansouri L; Smedby KE; Pedersen LB; van Lom K; Giudicelli V; Francova HS; Nguyen-Khac F; Panagiotidis P; Juliusson G; Angelis L; Anagnostopoulos A; Lefranc M-P; Facco M; Trentin L; Catherwood M; Montillo M; Geisler CH; Langerak AW; Pospisilova S; Chiorazzi N; Oscier D; Jelinek DF; Darzentas N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: LEUKEMIA AND LYMPHOMA. 2014;55(8):1781-1787
Familial CD3+ T large granular lymphocyte leukemia: evidence that genetic predisposition and antigen selection promote clonal cytotoxic T-cell responses.
Stalika E; Papalexandri A; Iskas M; Stavroyianni N; Kanellis G; Kotta K; Pontikoglou C; Siorenta A; Anagnostopoulos A; Papadaki H; Papadaki T; Stamatopoulos K
Article: JOURNAL OF IMMUNOLOGY. 2014;192(10):4518-4524
Heterogeneous functional effects of concomitant B cell receptor and TLR stimulation in chronic lymphocytic leukemia with mutated versus unmutated Ig genes.
Chatzouli M; Ntoufa S; Papakonstantinou N; Chartomatsidou E; Anagnostopoulos A; Kollia P; Ghia P; Muzio M; Stamatopoulos K; Belessi C
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2014;89(3):249-255
Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data.
Baliakas P; Iskas M; Gardiner A; Davis Z; Plevova K; Nguyen-Khac F; Malcikova J; Anagnostopoulos A; Glide S; Mould S; Stepanovska K; Brejcha M; Belessi C; Davi F; Pospisilova S; Athanasiadou A; Stamatopoulos K; Oscier D
Article: BLOOD. 2014;123(8):1199-1206
Clonal B-cell lymphocytosis exhibiting immunophenotypic features consistent with a marginal-zone origin: is this a distinct entity?
Xochelli A; Kalpadakis C; Gardiner A; Baliakas P; Vassilakopoulos TP; Mould S; Davis Z; Stalika E; Kanellis G; Angelopoulou MK; McIver-Brown N; Ibbotson R; Sachanas S; Korkolopoulou P; Athanasiadou A; Anagnostopoulos A; Papadaki HA; Papadaki T; Stamatopoulos K; Pangalis GA; Oscier D
Article: CLINICAL CANCER RESEARCH. 2014;20(2):323-330
IgG-Switched CLL Has a Distinct Immunogenetic Signature from the Common MD Variant: Ontogenetic Implications
Vardi A; Agathangelidis A; Sutton L-A; Chatzouli M; Scarfo L; Mansouri L; Douka V; Anagnostopoulos A; Darzentas N; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Article: EPIGENETICS. 2013;8(12):1280-1288
A key role for EZH2 in epigenetic silencing of HOX genes in mantle cell lymphoma
Kanduri M; Sander B; Ntoufa S; Papakonstantinou N; Sutton L; Stamatopoulos K; Kanduri C; Rosenquist R
Article: LEUKEMIA. 2013;27(11):2196-2199
Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2
Strefford JC; Sutton L-A; Baliakas P; Agathangelidis A; Malcikova J; Plevova K; Scarfo L; Davis Z; Stalika E; Cortese D; Cahill N; Pedersen LB; di Celle PF; Tzenou T; Geisler C; Panagiotidis P; Langerak AW; Chiorazzi N; Pospisilova S; Oscier D; Davi F; Belessi C; Mansouri L; Ghia P; Stamatopoulos K; Rosenquist R
Article: BLOOD. 2013;122(15):2673-2682
Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome
Chigrinova E; Rinaldi A; Kwee I; Rossi D; Rancoita PMV; Strefford JC; Oscier D; Stamatopoulos K; Papadaki T; Berger F; Young KH; Murray F; Rosenquist R; Greiner TC; Chan WC; Orlandi EM; Lucioni M; Marasca R; Inghirami G; Ladetto M; Forconi F; Cogliatti S; Votavova H; Swerdlow SH; Stilgenbauer S; Piris MA; Matolcsy A; Spagnolo D; Nikitin E; Zamo A; Gattei V; Bhagat G; Ott G; Zucca E; Gaidano G; Bertoni F
Article: MOLECULAR MEDICINE. 2013;19(1):230-236
Temporal Dynamics of Clonal Evolution in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-34/IGKV2-30 Antigen Receptors: Longitudinal Immunogenetic Evidence
Sutton L-A; Kostareli E; Stalika E; Tsaftaris A; Anagnostopoulos A; Darzentas N; Rosenquist R; Stamatopoulos K
Article: EPIGENETICS. 2012;7(12):1435-1442
Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles
Kanduri M; Marincevic M; Halldorsdottir AM; Mansouri L; Junevik K; Ntoufa S; Kultima HG; Isaksson A; Juliusson G; Andersson P-O; Ehrencrona H; Stamatopoulos K; Rosenquist R
Article: CANCER RESEARCH. 2012;72(20):5307-5316
Molecular Subsets of Mantle Cell Lymphoma Defined by the IGHV Mutational Status and SOX11 Expression Have Distinct Biologic and Clinical Features
Navarro A; Clot G; Royo C; Jares P; Hadzidimitriou A; Agathangelidis A; Bikos V; Darzentas N; Papadaki T; Salaverria I; Pinyol M; Puig X; Palomero J; Carmela Vegliante M; Amador V; Martinez-Trillos A; Stefancikova L; Wiestner A; Wilson W; Pott C; Jose Calasanz M; Trim N; Erber W; Sander B; Ott G; Rosenwald A; Colomer D; Gine E; Siebert R; Lopez-Guillermo A; Stamatopoulos K; Bea S; Campo E
Article: ANTICANCER RESEARCH. 2012;32(8):3125-3136
Screening for Cytotoxic Compounds in Poor-prognostic Chronic Lymphocytic Leukemia
Norberg M; Lindhagen E; Kanduri M; Rickardson L; Sundstrom C; Stamatopoulos K; Rosenquist R; Aleskog A
Article: BLOOD. 2012;119(19):4467-4475
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
Agathangelidis A; Darzentas N; Hadzidimitriou A; Brochet X; Murray F; Yan X-J; Davis Z; van Gastel-Mol EJ; Tresoldi C; Chu CC; Cahill N; Giudicelli V; Tichy B; Pedersen LB; Foroni L; Bonello L; Janus A; Smedby K; Anagnostopoulos A; Merle-Beral H; Laoutaris N; Juliusson G; di Celle PF; Pospisilova S; Jurlander J; Geisler C; Tsaftaris A; Lefranc M-P; Langerak AW; Oscier DG; Chiorazzi N; Belessi C; Davi F; Rosenquist R; Ghia P; Stamatopoulos K
Article: AMERICAN JOURNAL OF HEMATOLOGY. 2012;87(4):361-367
Mantle cell lymphoma displays a homogenous methylation profile: A comparative analysis with chronic lymphocytic leukemia
Halldorsdottir AM; Kanduri M; Marincevic M; Mansouri L; Isaksson A; Goransson H; Axelsson T; Agarwal P; Jernberg-Wiklund H; Stamatopoulos K; Sander B; Ehrencrona H; Rosenquist R
Article: BLOOD. 2011;118(11):3088-3095
Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases
Hadzidimitriou A; Agathangelidis A; Darzentas N; Murray F; Delfau-Larue M-H; Pedersen LB; Navarro Lopez A; Dagklis A; Rombout P; Beldjord K; Kolstad A; Dreyling MH; Anagnostopoulos A; Tsaftaris A; Mavragani-Tsipidou P; Rosenwald A; Ponzoni M; Groenen P; Ghia P; Sander B; Papadaki T; Campo E; Geisler C; Rosenquist R; Davi F; Pott C; Stamatopoulos K
Article: LEUKEMIA. 2011;25(6):979-984
Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC review board for reliable interpretation of problematic cases
Langerak AW; Davi F; Ghia P; Hadzidimitriou A; Murray F; Potter KN; Rosenquist R; Stamatopoulos K; Belessi C
Article: HAEMATOLOGICA. 2010;95(12):2072-2079
Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors
Marincevic M; Mansouri M; Kanduri M; Isaksson A; Goransson H; Smedby KE; Jurlander J; Juliusson G; Davi F; Stamatopoulos K; Rosenquist R
Article: HAEMATOLOGICA. 2010;95(9):1519-1525
High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors
Marincevic M; Cahill N; Gunnarsson R; Isaksson A; Mansouri M; Goransson H; Rasmussen M; Jansson M; Ryan F; Karlsson K; Adami H-O; Davi F; Jurlander J; Juliusson G; Stamatopoulos K; Rosenquist R
Article: LEUKEMIA. 2010;24(7):1317-1324
Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution
Kostareli E; Sutton L-A; Hadzidimitriou A; Darzentas N; Kouvatsi A; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: LEUKEMIA. 2010;24(1):125-132
A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence
Darzentas N; Hadzidimitriou A; Murray F; Hatzi K; Josefsson P; Laoutaris N; Moreno C; Anagnostopoulos A; Jurlander J; Tsaftaris A; Chiorazzi N; Belessi C; Ghia P; Rosenquist R; Davi F; Stamatopoulos K
Article: BLOOD. 2009;114(20):4460-4468
Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen
Sutton L-A; Kostareli E; Hadzidimitriou A; Darzentas N; Tsaftaris A; Anagnostopoulos A; Rosenquist R; Stamatopoulos K
Article: BLOOD. 2009;113(2):403-411
Evidence for the significant role of immunoglobulin light chains in antigen recognition and selection in chronic lymphocytic leukemia
Hadzidimitriou A; Darzentas N; Murray F; Smilevska T; Arvaniti E; Tresoldi C; Tsaftaris A; Laoutaris N; Anagnostopoulos A; Davi F; Ghia P; Rosenquist R; Stamatopoulos K; Belessi C
Article: BLOOD. 2008;111(3):1524-1533
Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis
Murray F; Darzentas N; Hadzidimitriou A; Tobin G; Boudjogra M; Scielzo C; Laoutaris N; Karlsson K; Baran-Marzsak F; Tsaftaris A; Moreno C; Anagnostopoulos A; Caligaris-Cappio F; Vaur D; Ouzounis C; Belessi C; Ghia P; Davi F; Rosenquist R; Stamatopoulos K
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Review: LEUKEMIA. 2024;38(7):1474-1476
Immunogenetics in hematopathology and hematology: why a common language is important
Stamatopoulos K; Bruford E; Campo E; Lefranc M-P
Letter: LEUKEMIA. 2024;38(3):679-680
Updates of the ERIC recommendations on how to report the results from immunoglobulin heavy variable gene analysis in chronic lymphocytic leukemia
Chatzikonstantinou T; Agathangelidis A; Chatzidimitriou A; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K
Corrigendum: LEUKEMIA. 2023;37(9):1944-1951
The 5th edition of The World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms (vol 36, pg 1720, 2022)
Alaggio R; Amador C; Anagnostopoulos I; Attygalle AD; de Oliveira Araujo IB; Berti E; Bhagat G; Borges AM; Boyer D; Calaminici M; Chadburn A; Chan JKC; Cheuk W; Chng W-J; Choi JK; Chuang S-S; Coupland SE; Czader M; Dave SS; de Jong D; Di Napoli A; Du M-Q; Elenitoba-Johnson KS; Ferry J; Geyer J; Gratzinger D; Guitart J; Gujral S; Harris M; Harrison CJ; Hartmann S; Hochhaus A; Jansen PM; Karube K; Kempf W; Khoury J; Kimura H; Klapper W; Kovach AE; Kumar S; Lazar AJ; Lazzi S; Leoncini L; Leung N; Leventaki V; Li X-Q; Lim MS; Liu W-P; Louissaint AJ; Marcogliese A; Medeiros LJ; Michal M; Miranda RN; Mitteldorf C; Montes-Moreno S; Morice W; Nardi V; Naresh KN; Natkunam Y; Ng S-B; Oschlies I; Ott G; Parrens M; Pulitzer M; Rajkumar SV; Rawstron AC; Rech K; Rosenwald A; Said J; Sarkozy C; Sayed S; Saygin C; Schuh A; Sewell W; Siebert R; Sohani AR; Suzuki R; Tooze R; Traverse-Glehen A; Vega F; Vergier B; Wechalekar AD; Wood B; Xerri L; Xiao W; Akinola NO; Akkari Y; Allende LM; Aozasa K; Araujo I; Arcaini L; Ardeshna KM; Asano N; Attarbaschi A; Bacon CM; Barrans SL; Batchelor T; Battistella M; Baughn LB; Behdad A; Berentsen S; Bianchi G; Bledsoe J; Borchmann P; Bower M; Buldini B; Burger JA; Burkhardt B; Cassaday RD; Cazzaniga G; Cerf-Bensussan N; Cesarman E; Chandy M; Chapman JR; Chapuy B; Chen X; Cheng CL; Chiattone C; Chiorazzi N; Cook LB; Cooper WA; Corboy GP; Cowan AJ; Cozzolino I; Cree IA; d'Amore ESG; Davies AJ; Deckert M; Delabie J; Demicco EG; Deshpande V; Diepstra A; Dierickx D; Dunleavy K; Eichhorst B; Ennishi D; Fajgenbaum DC; Farinha P; Fernandez de Larrea C; Fisher KE; Fitzgibbon J; Flanagan M; Fromm J; Garcia JF; Geddie WR; Gertz M; Gopal A; Gopal S; Greipp PT; Gru A; Gupta R; Hansmann M-L; Hebeda KM; Herfarth K; Herling M; Hermine O; Khe H-X; Hodge J; Hu S; Huang Y; Hung YP; Hunger S; Inaba H; Inagaki H; Iqbal J; Ishitsuka K; Iwaki N; Iwatsuki K; Jain N; Jeon YK; Kadin M; Kaji S; Kakkar A; Karadimitris A; Kataoka K; Kato S; Kersten MJ; Ketterling RP; Kim JE; Kratz CP; Kridel R; Kristinsson S; Kuppers R; Kuzu I; Yok-Lam; Lacasce A; Lamant-Rochaix L; Lamy T; Landgren O; Laskar S; Laskin WB; Lenz G; Li S; Di Li G; Lin P; Locatelli F; Lorsbach RB; Lossos I; Loughran TPJ; Macon WR; Maleszewski JJ; Malhotra P; Marafioti T; Maruyama D; Marx A; Mbulaiteye SM; Meignin V; Mejstrikova E; Michelow P; Miettinen M; Miles RR; Miyoshi H; Molina TJ; Mollejo M; Momose S; Mori T; Morice WG; Nadel B; Nagai H; Nagane M; Nair R; Nakamura N; Nakazawa A; Nasr S; Nicholson AG; Nicolae A; Ohgami RS; Oishi N; Olson TS; Ortonne N; Paiva B; Pan-Hammarstrom Q; Parihar M; Paulli M; Petersen A; Picarsic J; Pileri A; Pimpinelli N; Plaza JA; Rabin KR; Raderer M; Rai K; Randen U; Rao H; Robson A; Rochford R; Rosenquist R; Rossi D; Rossi ED; Rule S; Rymkiewicz G; Sabattini E; Saha V; Sakata-Yanagimoto M; Sander CA; Sangueza JM; Sangueza OP; Santucci M; Sato Y; Satou A; Schafernak KT; Schmitt F; Semenzato G; Sengar M; Shanafelt T; Shimada K; Slack GW; Slager S; Soffietti R; Solomon DA; Stamatopoulos K; Steidl C; Stilgenbauer S; Sukswai N; Takeuchi K; Tallini G; Tamaru J; Tan S-Y; Tembhare P; Tiacci E; Tokura Y; Tournilhac O; Treon S; Truemper L; Tsukasaki K; van Rhee F; Varghese A; Vermeer MH; Vielh P; Walker B; Wang M; Wang H-Y; Wang Z; Watanabe T; Weigert O; Wein-Stock D; Whittaker SJ; Willemze R; Woessmann W; Wu CJ; Yamaguchi M; Yamamoto H; Yamashita D; Yang S; Yang DT; Yasuda T; Yin W-H; Zen Y; Zhao S; Zhao W-L
Corrigendum: LEUKEMIA. 2023;37(2):504
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY (Dec, 10.1038/s41375-022-01802-y, 2022)
Mansouri L; Thorvaldsdottir B; Sutton L-A; Karakatsoulis G; Meggendorfer M; Parker H; Nadeu F; Brieghel C; Laidou S; Moia R; Rossi D; Catherwood M; Kotaskova J; Delgado J; Rodriguez-Vicente AE; Benito R; Rigolin GM; Bonfiglio S; Scarfo L; Mattsson M; Davis Z; Gogia A; Rani L; Baliakas P; Foroughi-Asl H; Jylha C; Skaftason A; Rapado I; Miras F; Martinez-Lopez J; de la Serna J; Rivas JMH; Thornton P; Larrayoz MJ; Calasanz MJ; Fesus V; Matrai Z; Bodor C; Smedby KE; Espinet B; Puiggros A; Gupta R; Bullinger L; Bosch F; Tazon-Vega B; Baran-Marszak F; Oscier D; Nguyen-Khac F; Zenz T; Terol MJ; Cuneo A; Hernandez-Sanchez M; Pospisilova S; Mills K; Gaidano G; Niemann CU; Campo E; Strefford JC; Ghia P; Stamatopoulos K; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2022;84:1-2
Precision medicine in cancer: A paradigm shift
Rosenquist R; Frohling S; Stamatopoulos K
Review: LEUKEMIA. 2022;36(8):1961-1968
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: the 2022 update of the recommendations by ERIC, the European Research Initiative on CLL
Agathangelidis A; Chatzidimitriou A; Chatzikonstantinou T; Tresoldi C; Davis Z; Giudicelli V; Kossida S; Belessi C; Rosenquist R; Ghia P; Langerak AW; Davi F; Stamatopoulos K
Editorial comment: HEMASPHERE. 2022;6(6):e726
The EHA Research Roadmap: Malignant Lymphoid Diseases.
Dreyling M; André M; Gökbuget N; Tilly H; Jerkeman M; Gribben J; Ferreri A; Morel P; Stilgenbauer S; Fox C; Maria Ribera J; Zweegman S; Aurer I; Bödör C; Burkhardt B; Buske C; Dollores Caballero M; Campo E; Chapuy B; Davies A; de Leval L; Doorduijn J; Federico M; Gaulard P; Gay F; Ghia P; Grønbæk K; Goldschmidt H; Kersten M-J; Kiesewetter B; Landman-Parker J; Le Gouill S; Lenz G; Leppä S; Lopez-Guillermo A; Macintyre E; Mantega MVM; Moreau P; Moreno C; Nadel B; Okosun J; Owen R; Pospisilova S; Pott C; Robak T; Spina M; Stamatopoulos K; Stary J; Tarte K; Tedeschi A; Thieblemont C; Trappe RU; Trümper LH; Salles G
Letter: LEUKEMIA AND LYMPHOMA. 2021;62(13):3288-3291
TAp63 and BCL2 expression are co-affected by cell-extrinsic signals in chronic lymphocytic leukemia
Koutroumani M; Laidou S; Kotta K; Stamatopoulos K
Review: CANCERS. 2021;13(13):3255
T Cell Defects and Immunotherapy in Chronic Lymphocytic Leukemia
Vlachonikola E; Stamatopoulos K; Chatzidimitriou A
Letter: HAEMATOLOGICA. 2021;106(4):1178-1181
Infrequent "chronic lymphocytic leukemia-specific" immunoglobulin stereotypes in aged individuals with or without low-count monoclonal B-cell lymphocytosis
Agathangelidis A; Galigalidou C; Scarfo L; Moysiadis T; Rovida A; Gounari M; Psomopoulos F; Ranghetti P; Galanis A; Davi F; Stamatopoulos K; Chatzidimitriou A; Ghia P
Letter: HEMASPHERE. 2021;5(3):e546
Assessing Patients' Knowledge on Chronic Lymphocytic Leukemia: Validation of the ERIC CLL Knowledge Questionnaire in Greece
Karamanidou C; Xochelli A; Papaioannou M; Moysiadis T; Scarfo L; Mattsson M; Stavroyianni N; Rosenquist R; Ghia P; Stamatopoulos K
Published conference paper: BLOOD. 2021;137(2):216-231
Triggering interferon signaling in T cells with avadomide sensitizes CLL to anti-PD-L1 /PD-1 immunotherapy
Ioannou N; Hagner PR; Stokes M; Gandhi AK; Apollonio B; Fanous M; Papazoglou D; Sutton L-A; Rosenquist R; Amini R-M; Chiu H; Lopez-Girona A; Janardhanan P; Awan FT; Jones J; Kay NE; Shanafelt TD; Tallman MS; Stamatopoulos K; Patten PEM; Vardi A; Ramsay AG
Review: FRONTIERS IN ONCOLOGY. 2021;11:769612
Understanding Monoclonal B Cell Lymphocytosis: An Interplay of Genetic and Microenvironmental Factors
Galigalidou C; Zaragoza-Infante L; Iatrou A; Chatzidimitriou A; Stamatopoulos K; Agathangelidis A
Review: FRONTIERS IN ONCOLOGY. 2021;11:771454
Distinctive Signaling Profiles With Distinct Biological and Clinical Implications in Aggressive CLL Subsets With Stereotyped B-Cell Receptor Immunoglobulin
Gerousi M; Laidou S; Gemenetzi K; Stamatopoulos K; Chatzidimitriou A
Letter: HAEMATOLOGICA. 2020;105(12):2864-2867
Chronic lymphocytic leukemias with trisomy 12 show a distinct DNA methylation profile linked to altered chromatin activation
Tsagiopoulou M; Chapaprieta V; Duran-Ferrer M; Moysiadi T; Psomopoulos F; Kollia P; Papakonstantinou N; Campo E; Stamatopoulos K; Martin-Subero JI
Letter: HAEMATOLOGICA. 2020;105(10):e515
High-throughput analysis of the T cell receptor gene repertoire in low-count monoclonal B cell lymphocytosis reveals a distinct profile from chronic lymphocytic leukemia.
Agathangelidis A; Galigalidou C; Scarfò L; Moysiadis T; Rovida A; Vlachonikola E; Sofou E; Psomopoulos F; Vardi A; Ranghetti P; Siorenta A; Galanis A; Stamatopoulos K; Chatzidimitriou A; Ghia P
Editorial comment: HEMASPHERE. 2020;4(5):e425
Challenges and Solutions for Collecting and Analyzing Real World Data: The Eric CLL Database as an Illustrative Example
Chatzidimitriou A; Minga E; Chatzikonstantinou T; Moreno C; Stamatopoulos K; Ghia P
Letter: AMERICAN JOURNAL OF HEMATOLOGY. 2020;95(7):E163-E166
Increased frequency of the single nucleotide polymorphism of the DARC/ACKR1 gene associated with ethnic neutropenia in a cohort of European patients with chronic idiopathic neutropenia
Fragiadaki I; Papadakis S; Sevastaki G; Sfyridaki K; Mavroudi I; Goulielmos GN; Kanellou P; Mortberg A; Hoglund P; Gemenetzi K; Stamatopoulos K; Chatzidimitriou A; Palmblad J; Papadaki HA
Editorial comment: HEMASPHERE. 2020;4(3):e406
Congenital and Acquired Chronic Neutropenias: Challenges, Perspectives and Implementation of the EuNet-INNOCHRON Action
Papadaki HA; Mavroudi I; Almeida A; Bux J; Cichy J; Dale DC; Donadieu J; Hoglund P; Karanfilski O; Mecucci C; Palmblad J; Skokowa J; Stamatopoulos K; Touw I; Warren AJ; Welte K; Zeidler C; Dufour C
Review: FRONTIERS IN IMMUNOLOGY. 2020;11:612244
T Cells in Chronic Lymphocytic Leukemia: A Two-Edged Sword
Vlachonikola E; Stamatopoulos K; Chatzidimitriou A
Letter: LEUKEMIA. 2019;33(7):1801-1805
Different time-dependent changes of risk for evolution in chronic lymphocytic leukemia with mutated or unmutated antigen B cell receptors
Moysiadis T; Baliakas P; Rossi D; Catherwood M; Strefford JC; Delgado J; Anagnostopoulos A; Belessi C; Stavroyianni N; Pospisilova S; Oscier D; Gaidano G; Campo E; Rosenquist R; Ghia P; Stamatopoulos K
Letter: LEUKEMIA. 2019;33(4):1030-1051
Dichotomous Toll-like receptor responses in chronic lymphocytic leukemia patients under ibrutinib treatment.
Gounari M; Ntoufa S; Gerousi M; Vilia MG; Moysiadis T; Kotta K; Papakonstantinou N; Scarfò L; Agathangelidis A; Fonte E; Ranghetti P; Nenou A; Xochelli A; Coscia M; Tedeschi A; Stavroyianni N; Muzio M; Stamatopoulos K; Ghia P
Review: METHODS IN MOLECULAR BIOLOGY. 2019;1956:139-155
Stereotyped B Cell Receptor Immunoglobulins in B Cell Lymphomas.
Agathangelidis A; Psomopoulos F; Stamatopoulos K
Review: LEUKEMIA. 2018;32(5):1070-1080
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation
Malcikova J; Tausch E; Rossi D; Sutton LA; Soussi T; Zenz T; Kater AP; Niemann CU; Gonzalez D; Davi F; Gonzalez Diaz M; Moreno C; Gaidano G; Stamatopoulos K; Rosenquist R; Stilgenbauer S; Ghia P; Pospisilova S
Letter: HAEMATOLOGICA. 2018;103(4):E158-E161
No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy
Baliakas P; Mattsson M; Hadzidimitriou A; Minga E; Agathangelidis A; Sutton L-A; Scarfo L; Davis Z; Yan X-J; Plevova K; Sandberg Y; Vojdeman FJ; Tzenou T; Chu CC; Veronese S; Mansouri L; Smedby KE; Giudicelli V; Nguyen-Khac F; Panagiotidis P; Juliusson G; Anagnostopoulos A; Lefranc M-P; Trentin L; Catherwood M; Montillo M; Niemann CU; Langerak AW; Pospisilova S; Stavroyianni N; Chiorazzi N; Oscier D; Jelinek DF; Shanafelt T; Darzentas N; Belessi C; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Editorial comment: ONCOTARGET. 2017;8(59):99209-99210
T cells in chronic lymphocytic leukemia: can they fight?
Vardi A; Stamatopoulos K; Hadzidimitriou A
Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):395-414
Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment
Ghia P; Nadel B; Sander B; Stamatopoulos K; Stevenson FK
Editorial comment: LEUKEMIA. 2017;31(7):1477-1481
Immunoglobulin gene sequence analysis in chronic lymphocytic leukemia: updated ERIC recommendations
Rosenquist R; Ghia P; Hadzidimitriou A; Sutton L-A; Agathangelidis A; Baliakas P; Darzentas N; Giudicelli V; Lefranc M-P; Langerak AW; Belessi C; Davi F; Stamatopoulos K
Editorial comment: HAEMATOLOGICA. 2017;102(6):968-971
Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification
Sutton L-A; Hadzidimitriou A; Baliakas P; Agathangelidis A; Langerak AW; Stilgenbauer S; Pospisilova S; Davis Z; Forconi F; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Letter: LEUKEMIA AND LYMPHOMA. 2017;58(3):726-728
Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors.
Gemenetzi K; Galigalidou C; Vlachonikola E; Stalika E; Xochelli A; Baliakas P; Karypidou M; Touloumenidou T; Minga E; Douka V; Iskas M; Athanasiadou A; Makris A; Stavroyianni N; Anagnostopoulos A; Hadzidimitriou A; Stamatopoulos K
Review: LEUKEMIA. 2017;31(2):282-291
Antigen receptor stereotypy in chronic lymphocytic leukemia
Stamatopoulos K; Agathangelidis A; Rosenquist R; Ghia P
Published conference paper: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2017;988:127-138
Chronic Lymphocytic Leukemia Patient Clustering Based on Somatic Hypermutation (SHM) Analysis.
Polychronidou E; Xochelli A; Moschonas P; Papadopoulos S; Hatzidimitriou A; Vlamos P; Stamatopoulos K; Tzovaras D
Letter: HAEMATOLOGICA. 2016;101(9):e369-e373
ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres
Navrkalova V; Young E; Baliakas P; Radova L; Sutton L-A; Plevova K; Mansouri L; Ljungstrom V; Ntoufa S; Davis Z; Juliusson G; Smedby KE; Belessi C; Panagiotidis P; Touloumenidou T; Davi F; Langerak AW; Ghia P; Strefford JC; Oscier D; Mayer J; Stamatopoulos K; Pospisilova S; Rosenquist R; Trbusek M
Review: HAEMATOLOGICA. 2016;101(9):1002-1009
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond
Rosenquist R; Rosenwald A; Du M-Q; Gaidano G; Groenen P; Wotherspoon A; Ghia P; Gaulard P; Campo E; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2016;39:15-25
Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies.
Ntoufa S; Vilia MG; Stamatopoulos K; Ghia P; Muzio M
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2016;39:1-2
B-cell malignancies: All roads lead to NF-κB activation
Rosenquist R; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2016;39:40-48
NF-κB activation in chronic lymphocytic leukemia: A point of convergence of external triggers and intrinsic lesions
Mansouri L; Papakonstantinou N; Ntoufa S; Stamatopoulos K; Rosenquist R
Letter: HAEMATOLOGICA. 2016;101(7):e299-e302
Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference
Baliakas P; Puiggros A; Xochelli A; Sutton L-A; Nguyen-Khac F; Gardiner A; Plevova K; Minga E; Hadzidimitriou A; Walewska R; McCarthy H; Ortega M; Collado R; Gonzalez T; Granada I; Luno E; Kotaskova J; Moysiadis T; Davis Z; Stavroyianni N; Anagnostopoulos A; Strefford JC; Pospisilova S; Davi F; Athanasiadou A; Rosenquist R; Oscier D; Espinet B; Stamatopoulos K
Published conference paper: BMC BIOINFORMATICS. 2016;17 Suppl 5(Suppl 5):173
Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.
Kavakiotis I; Xochelli A; Agathangelidis A; Tsoumakas G; Maglaveras N; Stamatopoulos K; Hadzidimitriou A; Vlahavas I; Chouvarda I
Review: JOURNAL OF INTERNAL MEDICINE. 2016;279(4):347-357
Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
Baliakas P; Mattsson M; Stamatopoulos K; Rosenquist R
Editorial comment: HAEMATOLOGICA. 2016;101(3):263-265
Innovation In the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?
Pospisilova S; Sutton L-A; Malcikova J; Tausch E; Rossi D; Montserrat E; Moreno C; Stamatopoulos K; Gaidano G; Rosenquist R; Ghia P
Letter: BLOOD. 2015;126(8):1043-1044
Prognostic relevance of MYD88 mutations in CLL: the jury is still out
Baliakas P; Hadzidimitriou A; Agathangelidis A; Rossi D; Sutton L-A; Kminkova J; Scarfo L; Pospisilova S; Gaidano G; Stamatopoulos K; Ghia P; Rosenquist R
Review: LEUKEMIA AND LYMPHOMA. 2015;56(2):301-310
Splenic marginal-zone lymphoma: ontogeny and genetics.
Baliakas P; Strefford JC; Bikos V; Parry M; Stamatopoulos K; Oscier D
Review: LEUKEMIA AND LYMPHOMA. 2014;55(10):2252-2261
Stereotyped B-cell receptors in chronic lymphocytic leukemia.
Agathangelidis A; Vardi A; Baliakas P; Stamatopoulos K
Review: CANCER RESEARCH. 2014;74(16):4211-4216
Immunogenetic Studies of Chronic Lymphocytic Leukemia: Revelations and Speculations about Ontogeny and Clinical Evolution
Vardi A; Agathangelidis A; Sutton L-A; Ghia P; Rosenquist R; Stamatopoulos K
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2014;166(4):621-625
The frequency of TP53 gene defects differs between chronic lymphocytic leukaemia subgroups harbouring distinct antigen receptors
Malcikova J; Stalika E; Davis Z; Plevova K; Trbusek M; Mansouri L; Scarfo L; Baliakas P; Gardiner A; Sutton L-A; Francova HS; Agathangelidis A; Anagnostopoulos A; Tracy I; Makris A; Smardova J; Ghia P; Belessi C; Gonzalez D; Rosenquist R; Oscier D; Pospisilova S; Stamatopoulos K
Letter: CANCER GENETICS. 2014;207(6):281-283
Translocation t(2;7)(p11.2;q21.2): a rare genetic aberration associated with B-cell lymphoproliferative disorders of marginal-zone origin.
Xochelli A; Baliakas P; Moore S; Sole F; Wickham N; Salido M; Athanasiadou A; Oscier D; Stamatopoulos K
Letter: LEUKEMIA. 2014;28(3):694-696
Feasibility of targeted next-generation sequencing of the TP53 and ATM genes in chronic lymphocytic leukemia
Mansouri L; Sutton L-A; Ljungstrom V; Sorqvist EF; Gunnarsson R; Smedby KE; Juliusson G; Stamatopoulos K; Nilsson M; Rosenquist R
Editorial comment: SEMINARS IN CANCER BIOLOGY. 2013;23(6):397-398
Antigens in lymphoma development-Current knowledge and future directions Introduction
Rosenquist R; Davi F; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2013;23(6):399-409
Antigen selection in B-cell lymphomas-Tracing the evidence
Sutton L-A; Agathangelidis A; Belessi C; Darzentas N; Davi F; Ghia P; Rosenquist R; Stamatopoulos K
Letter: LEUKEMIA. 2012;26(5):1127-1131
Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity
Kostareli E; Gounari M; Janus A; Murray F; Brochet X; Giudicelli V; Pospisilova S; Oscier D; Foroni L; di Celle PF; Tichy B; Pedersen LB; Jurlander J; Ponzoni M; Kouvatsi A; Anagnostopoulos A; Thompson K; Darzentas N; Lefranc M-P; Belessi C; Rosenquist R; Davi F; Ghia P; Stamatopoulos K
Letter: LEUKEMIA. 2012;26(1):170-172
Coexistence of trisomies of chromosomes 12 and 19 in chronic lymphocytic leukemia occurs exclusively in the rare IgG-positive variant
Ibbotson R; Athanasiadou A; Sutton L-A; Davis Z; Gardiner A; Baliakas P; Gunnarsson R; Anagnostopoulos A; Juliusson G; Rosenquist R; Oscier D; Stamatopoulos K
Review: SEMINARS IN CANCER BIOLOGY. 2011;21(5):299-307
Unlocking the secrets of immunoglobulin receptors in mantle cell lymphoma: Implications for the origin and selection of the malignant cells
Agathangelidis A; Hadzidimitriou A; Rosenquist R; Stamatopoulos K
Letter: LEUKEMIA. 2008;22(1):212-214
Determination of IGHV gene mutational status in chronic lymphocytic leukemia: bioinformatics advances meet clinical needs
Davi F; Rosenquist R; Ghia P; Belessi C; Stamatopoulos K
Letter: LEUKEMIA. 2007;21(12):2539-2540
Reply to 'Male preponderance in chronic lymphocytic leukemia utilizing IGHV1-69' When size of the sample matters
Ghia P; Belessi C; Davi F; Rosenquist R; Stamatopoulos K
Editorial comment: LEUKEMIA. 2007;21(1):1-3
ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia
Ghia P; Stamatopoulos K; Belessi C; Moreno C; Stilgenbauer S; Stevenson F; Davi F; Rosenquist R
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