Karolina Kublickiene

Karolina Kublickiene

Principal Researcher | Docent
Visiting address: Baxter Novum, Hälsovägen 7, plan 5, 14186 Stockholm
Postal address: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Med njursjukdomar, 141 52 Huddinge
Part of:

About me

  • I am an Associated Professor in Obstetrics and Gynecology at Karolinska
    Institutet. In addition, I am also:
    * Acting as a Senior scientist at the Department of Clinical Science
    Intervention and Technology [1], Unit for Renal Medicine, Karolinska
    University Hospital.
    * Acting as a Director for the Doctoral program in Development and
    Regeneration [2].
    * Founder of Gendered Innovation Alliance [3] at KI - a platform for
    knowledge sharing regarding implementation of gender dimension in research
    and educational content towards innovations in medicine and health care.
    * A TEDx Stockholm [4]advisory board member.
    * PI at KI for ACT [5], a new Horizon 2020 [6] EU project on Gender Equality
    &
  • Gender Dimension in research. Read more here [7].
    * PI at KI for the EU GenderNet Plus Co-Fund project [8]: Gender Outcomes
    INternational Group: to Further Well-being Development (GOING-FWD).
    To address growing societal and economic challenges, I believe that the role
    of the university is not limited to education and research but includes the
    "third mission". Both researchers and students can act as changemakers,
    engage with society and link the university’s activities with
    its socio-economic context to improve health for everybody.
    National Board of Medical Examiners, Diploma 1986

  • Specialist in Obstetrics &
  • Gynecology (1987-1992)

  • PhD 1997, KI, Obstetrics Gynecology
  • Title: Regulation of vascular tone in
    myometrial resistance arteries in normal pregnancy and preeclampsia

  • Knut och Alice Wallenberg’s Stiftelse Stipendiat (2000-2002) for Post-Doc
    at the Dep. of Maternal and Fetal Health, St Thomas’s Hospital London,
    King’s College and Inst. for Clinical Science Huddinge University Hospital
    1998-2002

  • Assistant Professor (2003-2007) Department of Clinical Science Intervention
    and Technology, Unit for Obstetrics and Gynecology (Huddinge), Karolinska
    University Hospital

  • Senior researcher (2008-2010) granted from KI for strategic researchers,
    Department of Clinical Science Intervention and Technology, Unit for
    Obstetrics and Gynecology (Huddinge), Karolinska University Hospital.
    [1] https://ki.se/orgid/932
    [2] https://ki.se/en/staff/doctoral-programme-in-development-and-regeneration-devreg-and-gendered-innovation-alliance
    [3] https://ki.se/en/staff/gendered-innovation-alliance-0
    [4] http://tedxstockholm.com/
    [5] https://act-on-gender.eu/?fbclid=IwAR0UguEyEgeRgsIu5_g3efmv7ozDTvZah2qo5480y_fYh-zxjmUrglsnT1E
    [6] https://ec.europa.eu/programmes/horizon2020/
    [7] https://ki.se/en/staff/act-a-new-horizon-2020-eu-project-on-gender-equality-gender-dimension-in-research
    [8] https://ki.se/en/news/research-projects-with-sex-and-gender-perspective-receive-msek-166

Research

  • Investigations concentrate on vascular physiology and pathophysiology with
    focus on resistance artery function in patients with chronic kidney disease,
    and in women at reproductive age and after menopause.
    Studies involve a range of different isolated small artery bioassays,
    pharmacological and molecular assessments of endothelial dysfunctional
    markers and cellular signalling in combination with in /in vivo /assessment
    of artery function and measurements of known and recently recognized
    biochemical markers for increased cardiovascular risk. Specific focus is on
    the early vascular ageing under uremic enviroment and effects of senolytics.
    Finally, in the latest EU and internationally granted projects, focus on
    implementation of the gender dimension in the research content and education,
    as well as identification of gender-related factors for the disease outcomes
    towards personalized approaches to chronic disease prevention, diagnosis and
    treatment.
    *Current focus:*
    * Chronic kidney disease and premature vascular ageing: focus on injury with
    potential for targeted interventions

  • * Specific targeting for prostaglandin E2 pathway

  • * Act on Gender: building Communities of Practice for gender equality in HE
    and R&
  • I (Horizon 2020, grant agreement No 788204,
    * Gender Outcomes International Group: to Further well-being Development
    (GOING-FVD
  • VR Dnr 4-94/2019)
    * Small artery function in normal pregnancy and preeclampsia

  • * Determination of cardiovascular risk factors and vascular function in
    women with history of preeclampsia

  • * History of preeclampsia and risk for end stage renal disease

  • * Dietary intervention in PCOS women and endothelial function

  • * ET-1-mediated endothelial dysfunction: implications for eNOS uncoupling
    and screening for mechanisms behind

  • * Resistance vasculature in chronic kidney disease: targeting compromised
    pathways and prerequisites for therapeutic alternatives

  • * Effects of different pharmacological agents with proposed cardiovascular
    benefit on endothelial function in arteries from women and men with and
    without CVD.
    /*For publications please see PubMed. [1] */
    [1] http://www.ncbi.nlm.nih.gov/pubmed/?term=Kublickiene+K

Teaching

  • Undergraduate and doctoral education, supervision for master's, PhD and Post
    Doc studies.
    Focus on vascular physiology and pathophysiology with focus on endothelial
    function.
    Particular interest on women's cardiovascular health at reproductive age and
    after menopause and implementation of sex/gender aspects in preclinical and
    clinical research towards innovation in health care.
    Portfolio: doctoral courses (Sex/gender aspects in biomedical research,
    Methodologies in clinical research, Artery function in health and disease and
    other EU courses for ITN and ESR), undergraduate courses (Gender aspects in
    health and disease).
    As a leader for the doctoral program in Development and Regeneration
    [1] (DEVREG), I not only work towards excellent multidisciplinary course
    curriculum, but also foster initiatives from students and encourage them for
    collaborative and creative initiatives to become future’s innovative
    scientists, leaders, company developers, social entrepreneurs and teachers.
    Since 2017, DEVREG has organized a number of TEDx inspired KI DEVREG Salons
    [2], forums for transferrable skills and important topics that are normally
    not covered by the curriculum. Learning for life, learning for change,
    learning for better world!
    In September 2018, I acted as one of the course leaders for The INTRICARE EU
    Horizon 2020 Marie Curie ITN course [3]. It was allocated to the KI DEVREG
    program and covered some of the latest advances in cardiovascular medicine:
    from basic to translational research with added value for transferable skills
    and on the implementation of the sex and gender perspectives in preclinical
    and clinical research.
    [1] https://ki.se/en/staff/doctoral-programme-in-development-and-regeneration-devreg-and-gendered-innovation-alliance
    [2] https://ki.se/en/staff/other-educational-activities-at-the-doctoral-programme-in-development-and-regeneration
    [3] https://ki.se/en/staff/intricare-eu-horizon-2020-marie-curie-itn-course-in-collaboration-with-devreg

Articles

All other publications

Grants

Employments

  • Principal Researcher, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2022-

Degrees and Education

  • Docent, Karolinska Institutet, 2009

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