Julia Spielbauer

Julia Spielbauer

Phd Student
Visiting address: Solnavägen 9 - kvarter D7, 17165 Solna
Postal address: C4 Neurovetenskap, C4 Forskning Olson, 171 77 Stockholm

About me

  • The main goal of my project is to decipher the role of the
    microbiota-gut-brain axis in typical and atypical brain development with a
    special focus on bacterial motifs called peptidoglycans.
    I am PhD student in the Olson lab [1], Department of Neuroscience at
    Karolinska Institutet. Additionally, I am volunteering as student
    representative in the student council of NeurotechEU [2].
    [1] https://ki.se/en/neuro/olson-laboratory
    [2] https://theneurotech.eu/


  • Environmental influences during early life, like the postnatal microbial
    colonization process, can have a severe impact on the development, structure,
    and function of the brain. Mice raised under germ-free (GF) conditions
    display increased motor activity and decreased anxiety-like behavior compared
    to mice with normal gut microbiota (specific pathogen-free
  • SPF).
    A mechanism involved in gut-microbiota-brain signaling is the activation of
    pattern recognition receptors (PRRs) within the developing brain. These
    receptors can recognize microbial components, for example, Peptidoglycans
    (PGNs) (components of the bacterial cell wall).
    Hence the overarching goal of my project is to investigate the influence of
    gut-derived microbial molecules on neuronal development, plasticity, and

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