Joy Roy

Publications
CV
Public outreach and news

Articles

Article: JOURNAL OF MEDICAL SCREENING. 2024;:9691413241278224
Anxiety and disease awareness in individuals with heredity for abdominal aortic aneurysm
Fattahi N; Nilsson O; Svensjoe S; Roy J; Linne A; Hultgren R
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2024;:S1078-5884(24)00800-1
Sealing Zone Failure Decreases the Long Term Durability of Endovascular Aneurysm Repair.
Sandström C; Andersson MB; Bogdanovic M; Fattahi N; Lundqvist R; Andersson M; Roy J; Hultgren R; Roos H
Article: BRITISH JOURNAL OF SURGERY. 2024;111(5):znae125
Peak wall rupture index is associated with risk of rupture of abdominal aortic aneurysms, independent of size and sex
Siika A; Talvitie M; Liljeqvist ML; Bogdanovic M; Gasser TC; Hultgren R; Roy J
Article: STRAHLENTHERAPIE UND ONKOLOGIE. 2024;200(5):425-433
Radiation therapy for cancer is potentially associated with reduced growth of concomitant abdominal aortic aneurysm
Von Rose AB; Kobus K; Bohmann B; Lindquist-Lilljequist M; Eilenberg W; Kapalla M; Bassermann F; Reeps C; Eckstein H-H; Neumayer C; Brostjan C; Roy J; Von Heckel K; Hultgren R; Schwaiger BJ; Combs SE; Busch A; Schiller K
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2024;44(3):666-689
Regulation of YAP Promotor Accessibility in Endothelial Mechanotransduction
Mannion AJ; Zhao H; Zhang Y; von Wright Y; Bergman O; Roy J; Saharinen P; Holmgren L
Article: BJS OPEN. 2024;8(1):zrad163
Prevalence of abdominal aortic aneurysm (AAA) in first-degree relatives: detecting AAA in adult offspring of AAA patients
Fattahi N; Linne A; Roy J; Stenman M; Svensjo S; Nilsson O; Hultgren R
Article: BRITISH JOURNAL OF SURGERY. 2024;111(1):znad376
Association of women-specific size threshold and mortality in elective abdominal aortic aneurysm repair
Talvitie M; Jonsson M; Roy J; Hultgren R
Article: MOLECULAR THERAPY: NUCLEIC ACIDS. 2023;33:848-865
The circular RNA Ataxia Telangiectasia Mutated regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms
Fasolo F; Winski G; Li Z; Wu Z; Winter H; Ritzer J; Glukha N; Roy J; Hultgren R; Pauli J; Busch A; Sachs N; Knappich C; Eckstein H-H; Boon RA; Paloschi V; Maegdefessel L
Article: BJS OPEN. 2023;7(5):zrad108
Learning curve in open groin hernia surgery: nationwide register-based study
Bladin O; Young N; Nordquist J; Roy J; Jarnbert-Pettersson H; Sandblom G; Lofgren J
Article: ACTA BIOMATERIALIA. 2023;167:147-157
Fracture of porcine aorta-Part 1: symconCT fracture testing and DIC
Alloisio M; Chatziefraimidou M; Roy J; Gasser TC
Article: JOURNAL OF VASCULAR SURGERY. 2023;78(3):657-667.e5
Women with large intact abdominal aortic aneurysms remain untreated
Talvitie M; Aldstedt-Nyronning L; Stenman M; Roy J; Cohnert T; Hultgren R
Article: NATURE CARDIOVASCULAR RESEARCH. 2023;2(7):629-644
The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms
Zhang Y; Zhang Y; Hutterer E; Hultin S; Bergman O; Kolbeinsdottir S; Jin H; Forteza MJ; Ketelhuth DFJ; Roy J; Hedin U; Enge M; Matic L; Eriksson P; Holmgren L
Article: SCIENTIFIC REPORTS. 2023;13(1):9283
Three-dimensional growth and biomechanical risk progression of abdominal aortic aneurysms under serial computed tomography assessment
Siika A; Bogdanovic M; Liljeqvist ML; Gasser TC; Hultgren R; Roy J
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2023;65(6):778-786
Long Term Mortality Rate in Patients Treated with Carotid Endarterectomy
Waden K; Hultgren R; Kotopouli MI; Gillgren P; Roy J; Hedin U; Matic L
Article: INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING. 2023;39(4):e3587
A quarter of a century biomechanical rupture risk assessment of abdominal aortic aneurysms. Achievements, clinical relevance, and ongoing developments
Gasser TC; Miller C; Polzer S; Roy J
Article: JVS - VASCULAR SCIENCE. 2023;4:100101
Histological evaluation of the aortic wall response following endovascular aneurysm repair and endovascular aneurysm sealing.
Bruijn LE; Heyligers JMM; Vriens PW; van Rhijn J; Roy J; Hamming JF; Gäbel G; Lindeman JHN
Article: JVS - VASCULAR SCIENCE. 2023;4:100104
Biomechanics and early sac regression after endovascular aneurysm repair of abdominal aortic aneurysm.
Bogdanovic M; Siika A; Lindquist Liljeqvist M; Gasser TC; Hultgren R; Roy J
Article: PILOT AND FEASIBILITY STUDIES. 2022;8(1):252
Evaluating feasibility of using national registries for identification, invitation, and ultrasound examination of persons with hereditary risk for aneurysm disease-detecting abdominal aortic aneurysms in first degree relatives (adult offspring) to AAA patients (DAAAD)
Hultgren R; Fattahi N; Nilsson O; Svensjo S; Roy J; Linne A
Journal article: JOURNAL OF VASCULAR SURGERY. 2022;76(5):1424
Structured Computed Tomography Analysis can Identify the Majority of Patients at Risk of Post-Endovascular Aortic Repair Rupture
Andersson M; Sandström C; Stackelberg O; Lundqvist R; Nordanstig J; Jonsson M; Roy J; Andersson M; Hultgren R; Roos H
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2022;64(2-3):166-174
Editor's Choice - Structured Computed Tomography Analysis can Identify the Majority of Patients at Risk of Post-Endovascular Aortic Repair Rupture
Andersson M; Sandstrom C; Stackelberg O; Lundqvist R; Nordanstig J; Jonsson M; Roy J; Andersson M; Hultgren R; Roos H
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2022;64(2-3):255-264
Radiation and Chemotherapy are Associated with Altered Aortic Aneurysm Growth in Patients with Cancer: Impact of Synchronous Cancer and Aortic Aneurysm
von Rose AB; Kobus K; Bohmann B; Lindquist-Lilljequist M; Eilenberg W; Bassermann F; Reeps C; Eckstein H-H; Trenner M; Maegdefessel L; Neumayer C; Brostjan C; Roy J; Hultgren R; Schwaiger BJ; Busch A
Article: ISCIENCE. 2022;25(5):104219
Clinical risk scores for stroke correlate with molecular signatures of vulnerability in symptomatic carotid patients
Waden K; Karlof E; Narayanan S; Lengquist M; Hansson GK; Hedin U; Roy J; Matic L
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2022;42(5):659-676
Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis
Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2022;12(2):e682
Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification
Skenteris NT; Seime T; Witasp A; Karlof E; Wasilewski GB; Heuschkel MA; Jaminon AMG; Oduor L; Dzhanaev R; Kronqvist M; Lengquist M; Peeters FECM; Soderberg M; Hultgren R; Roy J; Maegdefessel L; Arnardottir H; Bengtsson E; Goncalves I; Quertermous T; Goettsch C; Stenvinkel P; Schurgers LJ; Matic L
Article: JOURNAL OF VASCULAR SURGERY. 2022;75(1):205-212.e3
Natural history, growth rates, and treatment of popliteal artery aneurysms
Jergovic I; Cheesman MA; Siika A; Khashram M; Paris SM; Roy J; Hultgren R
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561
Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease
Suur BE; Chemaly M; Liljeqvist ML; Djordjevic D; Stenemo M; Bergman O; Karlof E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Article: JOURNAL OF VASCULAR SURGERY. 2021;74(6):2023-2029
Sex hormones in men with abdominal aortic aneurysm
Villard C; Roy J; Bogdanovic M; Eriksson P; Hultgren R
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2021;62(4):532-539
Limb Graft Occlusion Following Endovascular Aneurysm Repair for Infrarenal Abdominal Aortic Aneurysm with the Zenith Alpha, Excluder, and Endurant Devices: a Multicentre Cohort Study
Bogdanovic M; Stackelberg O; Lindstrom D; Ersryd S; Andersson M; Roos H; Siika A; Jonsson M; Roy J
Article: SCIENTIFIC REPORTS. 2021;11(1):18040
Geometric and biomechanical modeling aided by machine learning improves the prediction of growth and rupture of small abdominal aortic aneurysms
Liljeqvist ML; Bogdanovic M; Siika A; Gasser TC; Hultgren R; Roy J
Article: JOURNAL OF VASCULAR SURGERY. 2021;74(3):701-710.e3
A population-based study of post-endovascular aortic repair rupture during 15 years
Andersson M; Talvitie M; Benson L; Roy J; Roos H; Hultgren R
Article: JCI INSIGHT. 2021;6(15):140364
Lenvatinib halts aortic aneurysm growth by restoring smooth muscle cell contractility
Busch A; Pauli J; Winski G; Bleichert S; Chernogubova E; Metschl S; Winter H; Trenner M; Wiegering A; Otto C; Fischer J; Reiser J; Werner J; Roy J; Brostjan C; Knappich C; Eckstein H-H; Paloschi V; Maegdefessel L
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2021;10(5):e019592
Sex Differences in Rupture Risk and Mortality in Untreated Patients With Intact Abdominal Aortic Aneurysms
Talvitie M; Stenman M; Roy J; Leander K; Hultgren R
Article: PLOS ONE. 2021;16(12):e0261073
Plasma levels of leucocyte elastase-generated cross linked fibrin degradation products (E-XDP) are elevated in chronic venous disease
Sinabulya H; Silveira A; Blomgren L; Roy J
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2020;40(11):2700-2713
Tunica-Specific Transcriptome of Abdominal Aortic Aneurysm and the Effect of Intraluminal Thrombus, Smoking, and Diameter Growth Rate
Lindquist Liljeqvist M; Hultgren R; Bergman O; Villard C; Kronqvist M; Eriksson P; Roy J
Article: CARDIOVASCULAR RESEARCH (CVR). 2020;116(2):450-456
The effect of ticagrelor on growth of small abdominal aortic aneurysms-a randomized controlled trial
Wanhainen A; Mani K; Kullberg J; Svensjo S; Bersztel A; Karlsson L; Holst J; Gottsater A; Linne A; Gillgren P; Langenskiold M; Hultgren R; Roy J; Gilgen N-P; Ahlstrom H; Lederle FA; Bjorck M
Article: PLOS ONE. 2020;15(1):e0227889
Dipeptidyl peptidase-4 is increased in the abdominal aortic aneurysm vessel wall and is associated with aneurysm disease processes
Liljeqvist ML; Eriksson L; Villard C; Lengquist M; Kronqvist M; Hultgren R; Roy J
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2019;4(3):304-317
Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity
Jiang X; Wang F; Wang Y; Gistera A; Roy J; Paulsson-Berne G; Hedin U; Lerman A; Hansson GK; Herrmann J; Yan Z-Q
Article: PLOS ONE. 2019;14(5):e0216558
A large proportion of patients with small ruptured abdominal aortic aneurysms are women and have chronic obstructive pulmonary disease
Siika A; Liljeqvist ML; Zommorodi S; Nilsson O; Andersson P; Gasser TC; Roy J; Hultgren R
Article: JOURNAL OF ENDOVASCULAR THERAPY. 2018;25(6):750-756
Aortic Lumen Area Is Increased in Ruptured Abdominal Aortic Aneurysms and Correlates to Biomechanical Rupture Risk
Siika A; Liljeqvist ML; Hultgren R; Gasser TC; Roy J
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2018;3(6):719-727
Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms
Petri MH; Thul S; Andonova T; Lindquist-Liljeqvist M; Jin H; Skenteris N-T; Arnardottir H; Maegdefessel L; Caidahl K; Perretti M; Roy J; Back M
Article: CIRCULATION. 2018;138(15):1551-1568
H19 Induces Abdominal Aortic Aneurysm Development and Progression
Li DY; Busch A; Jin H; Chernogubova E; Pelisek J; Karlsson J; Sennblad B; Liu S; Lao S; Hofmann P; Baecklund A; Eken SM; Roy J; Eriksson P; Dacken B; Ramanujam D; Dueck A; Engelhardt S; Boon RA; Eckstein H-H; Spin JM; Tsao PS; Maegdefessel L
Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2018;72(10):904-910
Understanding abdominal aortic aneurysm epidemiology: socioeconomic position affects outcome
Zommorodi S; Leander K; Roy J; Steuer J; Hultgren R
Article: JACC: BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):464-480
Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage
Matic LP; Iglesias MJ; Vesterlund M; Lengquist M; Hong M-G; Saieed S; Sanchez-Rivera L; Berg M; Razuvaev A; Kronqvist M; Lund K; Caidahl K; Gillgren P; Ponten F; Uhlen M; Schwenk JM; Hansson GK; Paulsson-Berne G; Fagman E; Roy J; Hultgren R; Bergstrom G; Lehtio J; Odeberg J; Hedin U
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2018;55(6):757-818
Editor's Choice - Vascular Access: 2018 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS).
Schmidli J; Widmer MK; Basile C; de Donato G; Gallieni M; Gibbons CP; Haage P; Hamilton G; Hedin U; Kamper L; Lazarides MK; Lindsey B; Mestres G; Pegoraro M; Roy J; Setacci C; Shemesh D; Tordoir JHM; van Loon M; Esvs Guidelines Committee; Kolh P; de Borst GJ; Chakfe N; Debus S; Hinchliffe R; Kakkos S; Koncar I; Lindholt J; Naylor R; Vega de Ceniga M; Vermassen F; Verzini F; Esvs Guidelines Reviewers; Mohaupt M; Ricco J-B; Roca-Tey R
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2018;38(5):1076-1085
CD40L Deficiency Protects Against Aneurysm Formation
Kusters PJH; Seijkens TTP; Beckers L; Lievens D; Winkels H; de Waard V; Duijvestijn A; Liljeqvist ML; Roy J; Daugherty A; Newby A; Gerdes N; Lutgens E
Article: THROMBOSIS AND HAEMOSTASIS. 2018;118(2):329-339
Neutrophil Elastase-Derived Fibrin Degradation Products Indicate Presence of Abdominal Aortic Aneurysms and Correlate with Intraluminal Thrombus Volume
Liljeqvist ML; Silveira A; Hultgren R; Frebelius S; Lengquist M; Engstrom J; Gasser TC; Eriksson P; Roy J
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2018;55(1):3-81
Editor's Choice - Management of Atherosclerotic Carotid and Vertebral Artery Disease: 2017 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS)
Naylor AR; Ricco JB; de Borst GJ; Debus S; de Haro J; Halliday A; Hamilton G; Kakisis J; Kakkos S; Lepidi S; Markus HS; McCabe DJ; Roy J; Sillesen H; van den Berg JC; Vermassen F; Kolh P; Chakfe N; Hinchliffe RJ; Koncar I; Lindholt JS; de Ceniga MV; Verzini F; Archie J; Bellmunt S; Chaudhuri A; Koelemay M; Lindahl AK; Padberg F; Venermo M
Article: JOURNAL OF VASCULAR SURGERY. 2017;65(4):1014-1021.e4
Gender, smoking, body size, and aneurysm geometry influence the biomechanical rupture risk of abdominal aortic aneurysms as estimated by finite element analysis
Liljeqvist ML; Hultgren R; Siika A; Gasser TC; Roy J
Article: MATURITAS. 2017;96:39-44
Differential expression of sex hormone receptors in abdominal aortic aneurysms
Villard C; Eriksson P; Kronqvist M; Lengquist M; Jorns C; Hartman J; Roy J; Hultgren R
Article: PLOS ONE. 2017;12(11):e0187421
Biomechanical changes during abdominal aortic aneurysm growth
Stevens RRF; Grytsan A; Biasetti J; Roy J; Liljeqvist ML; Gasser TC
Article: CARDIOVASCULAR RESEARCH (CVR). 2017;113(1):30-39
Low TLR7 gene expression in atherosclerotic plaques is associated withmajor adverse cardio- and cerebrovascular events
Karadimou G; Folkersen L; Berg M; Perisic L; Discacciati A; Roy J; Hansson GK; Persson J; Paulsson-Berne G
Article: WORLD JOURNAL OF SURGERY. 2016;40(12):3080-3087
A Majority of Admitted Patients With Ruptured Abdominal Aortic Aneurysm Undergo and Survive Corrective Treatment: A Population-Based Retrospective Cohort Study
Hultgren R; Zommorodi S; Gambe M; Roy J
Article: JOURNAL OF ENDOVASCULAR THERAPY. 2016;23(6):957-966
Local Diameter, Wall Stress, and Thrombus Thickness Influence the Local Growth of Abdominal Aortic Aneurysms
Martufi G; Liljeqvist ML; Sakalihasan N; Panuccio G; Hultgren R; Roy J; Gasser TC
Article: JOURNAL OF VASCULAR SURGERY. 2016;64(4):949-955.e1
High proportion of known abdominal aortic aneurysm in patients with rupture indicates surveillance deficiency
Zommorodi S; Roy J; Steuer J; Hultgren R
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(9):1947-1961
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM
Matic LP; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Rohl S; Kronqvist M; Aldi S; Magne J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojevic V; Lehtio J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: JOURNAL OF VASCULAR SURGERY. 2016;63(6):1434-1442.e3
Volume growth of abdominal aortic aneurysms correlates with baseline volume and increasing finite element analysis-derived rupture risk
Liljeqvist ML; Hultgren R; Gasser TC; Roy J
Article: ATHEROSCLEROSIS. 2016;249:101-109
Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm
Vorkapic E; Dugic E; Vikingsson S; Roy J; Mayranpaa MI; Eriksson P; Wagsater D
Article: JOURNAL OF INTERNAL MEDICINE. 2016;279(3):293-308
Gene expression signatures, pathways and networks in carotid atherosclerosis
Perisic L; Aldi S; Sun Y; Folkersen L; Razuvaev A; Roy J; Lengquist M; Akesson S; Wheelock CE; Maegdefessel L; Gabrielsen A; Odeberg J; Hansson GK; Paulsson-Berne G; Hedin U
Article: JOURNAL OF ENDOVASCULAR THERAPY. 2016;23(1):115-120
Prediction of Rupture Sites in Abdominal Aortic Aneurysms After Finite Element Analysis
Erhart P; Roy J; de Vries J-PPM; Liljeqvist ML; Grond-Ginsbach C; Hyhlik-Duerr A; Boeckler D
Article: THROMBOSIS AND HAEMOSTASIS. 2015;114(6):1165-1174
Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms
Folkesson M; Li C; Frebelius S; Swedenborg J; Wagsater D; Williams KJ; Eriksson P; Roy J; Liu M-L
Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2015;56(4):599-605
Endovascular treatment of true and false aneurysms in hemodialysis access
Heidin U; Engstrom J; Roy J
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2015;35(4):973-980
Aneurysm Development in Patients With a Bicuspid Aortic Valve Is Not Associated With Transforming Growth Factor-β Activation
Paloschi V; Gadin JR; Khan S; Bjorck HM; Du L; Maleki S; Roy J; Lindeman JHM; Mohamed SA; Tsuda T; Franco-Cereceda A; Eriksson P
Article: JOURNAL OF VASCULAR RESEARCH. 2015;52(1):41-52
Glucagon-Like Peptide-1 Receptor Activation Does Not Affect Re-Endothelialization but Reduces Intimal Hyperplasia via Direct Effects on Smooth Muscle Cells in a Nondiabetic Model of Arterial Injury
Eriksson L; Saxelin R; Rohl S; Roy J; Caidahl K; Nystrom T; Hedin U; Razuvaev A
Article: NATURE COMMUNICATIONS. 2014;5:5214
miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development
Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nagakami F; Heymann HM; Chernugobova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Article: JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. 2014;25(5):789-796.e7
Early Changes of Gene Expression Profiles in the Rat Model of Arterial Injury
Fedorov A; Kostareva A; Raud J; Roy J; Hedin U; Razuvaev A
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2014;47(3):288-295
A Novel Strategy to Translate the Biomechanical Rupture Risk of Abdominal Aortic Aneurysms to their Equivalent Diameter Risk: Method and Retrospective Validation
Gasser TC; Nchimi A; Swedenborg J; Roy J; Sakalihasan N; Boeckler D; Hyhlik-Duerr A
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2013;46(6):719-725
Vascular training profiles across Europe.
Avgerinos ED; European Vascular Surgeons in Training (EVST) Writ
Article: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2013;27:226-238
Identification of carotid plaque tissue properties using an experimental-numerical approach
Heiland VM; Forsell C; Roy J; Hedin U; Gasser TC
Article: JOURNAL OF VASCULAR SURGERY. 2013;58(3):748-755
Multidimensional growth measurements of abdominal aortic aneurysms
Martufi G; Auer M; Roy J; Swedenborg J; Sakalihasan N; Panuccio G; Gasser TC
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(9):2193-2201
NOD2-Mediated Innate Immune Signaling Regulates the Eicosanoids in Atherosclerosis
Liu H-Q; Zhang X-Y; Edfeldt K; Nijhuis MO; Idborg H; Back M; Roy J; Hedin U; Jakobsson P-J; Laman JD; de Kleijn DP; Pasterkamp G; Hansson GK; Yan Z-Q
Article: ANNALS OF BIOMEDICAL ENGINEERING. 2013;41(7):1554-1566
The Quasi-Static Failure Properties of the Abdominal Aortic Aneurysm Wall Estimated by a Mixed Experimental-Numerical Approach
Forsell C; Swedenborg J; Roy J; Gasser TC
Article: ACTA BIOMATERIALIA. 2012;8(8):3091-3103
Spatial orientation of collagen fibers in the abdominal aortic aneurysm's wall and its relation to wall mechanics
Gasser TC; Gallinetti S; Xing X; Forsell C; Swedenborg J; Roy J
Article: ATHEROSCLEROSIS. 2012;220(1):102-109
The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation
Wang J; Razuvaev A; Folkersen L; Hedin E; Roy J; Brismar K; Hedin U
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2011;42(6):722-730
Correlations Between Clinical Variables and Gene-expression Profiles in Carotid Plaque Instability
Razuvaev A; Ekstrand J; Folkersen L; Agardh H; Markus D; Swedenborg J; Hansson GK; Gabrielsen A; Paulsson-Berne G; Roy J; Hedin U
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2011;31(3):691-697
Impaired Splicing of Fibronectin Is Associated With Thoracic Aortic Aneurysm Formation in Patients With Bicuspid Aortic Valve
Paloschi V; Kurtovic S; Folkersen L; Gomez D; Wagsaeter D; Roy J; Petrini J; Eriksson MJ; Caidahl K; Hamsten A; Liska J; Michel J-B; Franco-Cereceda A; Eriksson P
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2010;40(2):176-185
Biomechanical Rupture Risk Assessment of Abdominal Aortic Aneurysms: Model Complexity versus Predictability of Finite Element Simulations
Gasser TC; Auer M; Labruto F; Swedenborg J; Roy J
Article: JOURNAL OF VASCULAR SURGERY. 2010;52(1):167-175
Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival
Ekstrand J; Razuvaev A; Folkersen L; Roy J; Hedin U
Article: JOURNAL OF VASCULAR SURGERY. 2008;48(5):1108-1113
Bleeding into the intraluminal thrombus in abdominal aortic aneurysms is associated with rupture
Roy J; Labruto F; Beckman MO; Danielson J; Johansson G; Swedenborg J
Article: ATHEROSCLEROSIS. 2008;199(2):310-316
Noninvasive real-time imaging of intima thickness after rat carotid artery balloon injury using ultrasound biomicroscopy
Razuvaev A; Lund K; Roy J; Hedin U; Caidahl K
Article: JOURNAL OF VASCULAR SURGERY. 2007;46(1):108-115
The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling
Razuvaev A; Henderson B; Girnita L; Larsson O; Axelson M; Hedin U; Roy J
Article: AMERICAN JOURNAL OF PHYSIOLOGY. HEART AND CIRCULATORY PHYSIOLOGY. 2007;292(6):H3158-H3163
Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation
Bulhak A; Roy J; Hedin U; Sjoquist P-O; Pernow J
Article: ATHEROSCLEROSIS. 2007;190(2):264-270
Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions
Tran P-K; Agardh HE; Tran-Lundmark K; Ekstrand J; Roy J; Henderson B; Gabrielsen A; Hansson GK; Swedenborg J; Paulsson-Berne G; Hedin U
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2005;25(7):1341-1346
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm
Kazi M; Zhu CY; Roy J; Paulsson-Berne G; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Article: CIRCULATION. 2003;107(11):1532-1538
Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability
Eriksson A; Cao RH; Roy J; Tritsaris K; Wahlestedt C; Dissing S; Thyberg J; Cao YH
Article: EXPERIMENTAL CELL RESEARCH. 2002;273(2):169-177
Fibronectin promotes cell cycle entry in smooth muscle cells in primary culture
Roy J; Tran PK; Religa P; Kazi M; Henderson B; Lundmark K; Hedin U
Article: DIFFERENTIATION. 2001;67(1-2):50-58
Phenotypic modulation of arterial smooth muscle coils is associated with prolonged activation of Erk1/2
Roy J; Kazi M; Hedin U; Thyberg J
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1997;17(10):1977-1984
Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotype
Hedin U; Thyberg J; Roy J; Dumitrescu A; Tran PK
Article: LABORATORY INVESTIGATION. 1997;77(1):93-101
Expression of caveolae on the surface of rat arterial smooth muscle cells is dependent on the phenotypic state of the cells
Thyberg J; Roy J; Tran PK; Blomgren K; Dumitrescu A; Hedin U
Article: JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY. 1997;45(6):837-846
Phenotypic modulation of smooth muscle cells after arterial injury is associated with changes in the distribution of laminin and fibronectin
Thyberg J; Blomgren K; Roy J; Tran PK; Hedin U
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All other publications

Letter: BRITISH JOURNAL OF SURGERY. 2024;111(7):znae174
Author response to: Comment on: Peak wall rupture index is associated with risk of rupture of abdominal aortic aneurysms, independent of size and sex
Siika A; Liljeqvist ML; Roy J
Editorial comment: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2024;68(1):49
Higher Risk of Limb Graft Occlusions: The Achilles Heel of the Zenith Alpha Abdominal Endovascular Graft
Roy J; Siika A
Review: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2023;65(2):233-243
Comparison of Methods for Monitoring Intra-operative Cerebral Perfusion in Patients Undergoing Carotid Endarterectomy with Selective Shunting: A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials and Cohort Studies
Jovanovic A; Jonsson M; Roy J; Eriksson J; Mutavdzic P; Trailovic R; Koncar I
Conference publication: BRITISH JOURNAL OF SURGERY. 2022;109:znac308.059
OC-047 LEARNING CURVE IN HERNIA SURGERY- A REGISTER BASED STUDY
Bladin O; Young N; Nordquist J; Roy J; Jarnbert Pettersson H; Sandblom G; Lofgren J
Editorial comment: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2021;62(6):857-858
Time to Act: Women Fare Worse After Complex Endovascular Aortic Repairs
Hultgren R; Roy J
Book chapter: BIOMECHANICS OF CORONARY ATHEROSCLEROTIC PLAQUE. 2021;p. 173-193
Chapter 7 The interaction of biochemical, biomechanical, and clinical factors of coronary disease Review and outlook
Gasser TC; Hedin U; Roy J
Editorial comment: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2020;60(1):107
Computational Modelling to Improve Arteriovenous Fistula Maturation Rates: Close But Not Yet There! COMMENT
Roy J
Published conference paper: BRITISH JOURNAL OF SURGERY. 2018;105(9):1135-1144
Value of risk scores in the decision to palliate patients with ruptured abdominal aortic aneurysm
Sweeting MJ; Ulug P; Roy J; Hultgren R; Indrakusuma R; Balm R; Thompson MM; Hinchliffe RJ; Thompson SG; Powell JT
Editorial comment: ATHEROSCLEROSIS. 2018;269:258-259
Stroke outcome is associated with baseline renal function: A risk factor that matters!
Roy J
Letter: JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. 2018;29(1):144-145
Localized Hyperattenuations in the Intraluminal Thrombus May Predict Rupture of Abdominal Aortic Aneurysms
Talvitie M; Liljeqvist ML; Siika A; Hultgren R; Roy J
Editorial comment: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2016;51(5):622
Commentary on 'Plaque Echolucency and the Risk of Ischaemic Stroke in Patients with Asymptomatic Carotid Stenosis Within the First Asymptomatic Carotid Surgery Trial (ACST-1)'
Roy J; Hedin U
Conference publication: 2016;:436-441
A Markov Decision Process Model to Guide Treatment of Abdominal Aortic Aneurysms
Mattila R; Siika A; Roy J; Wahlberg B
Letter: JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. 2012;23(10):1387-1388
CT Angiography of Abdominal Aortic Aneurysms: Not Everything That Is Not White Is Thrombus
Labruto F; Lundberg G; Roy J
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:72S-73S
A Specific Inhibitor of IGF-1 Receptor - Picropodophyllin Can Suppress Atheroma Progression and Has a Stabilizing Effect on Atherosclerotic Lesions in ApoE Deficient Mice
Razuvaev A; Larsson O; Axelson M; Hedin U; Roy J
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:80S
Regulation of Endothelin-1 and Endothelin Receptors by Shear Stress in Vascular Smooth Muscle Cells
Ekstrand J; Razuvaev A; Roy J; Hedin U
Book chapter: ENCYCLOPEDIC REFERENCE OF GENOMICS AND PROTEOMICS IN MOLECULAR MEDICINE. 2005;p. 730-734
Growth Factors
Hedin U; Roy J
Review: CURRENT OPINION IN LIPIDOLOGY. 2004;15(5):559-565
Control of smooth muscle cell proliferation in vascular disease
Hedin U; Roy J; Tran PK
Published conference paper: JOURNAL OF VASCULAR SURGERY. 2003;38(6):1283-1292
Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall
Kazi M; Thyberg J; Religa P; Roy J; Eriksson P; Hedin U; Swedenborg J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):254
Influence of intraluminal thrombus on cellular and structural features of the aneurysm wall
Kazi M; Thyberg J; Religa P; Roy J; Eriksson R; Ulf H; Swedenborg J
Thesis / dissertation: 2001
Extracellular matrix-mediated signaling in the regulation of vascular smooth muscle cell phenotype and function
Roy, Joy
Review: THROMBOSIS AND HAEMOSTASIS. 1999;82 Suppl 1:23-26
Control of smooth muscle cell proliferation--the role of the basement membrane.
Hedin U; Roy J; Tran PK; Lundmark K; Rahman A
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Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2027

Degrees and Education

Docent, Karolinska institutet, 2012
Doctor Of Philosophy, Dept of Surgical Science, Karolinska Institutet, 2001
University Medical Degree, Karolinska Institutet, 1997

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