Jonas Wastesson

About me
Publications
Grants
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About me

Senior research specialist at the Department of Medical Epidemiology and
Biostatistics, Karolinska Institutet.

Research

My research is mainly focused on different aspects of medication use among
older adults. Other research interests include use of health care and social
services in old age.

Articles

Journal article: PUBLIC HEALTH. 2025;242:324-331
Regional differences in COVID-19 vaccine uptake and their determinants among Swedish older adults.
Xu Y; Nyberg F; Santosa A; Marking U; Jonsson J; Gisslén M; Wastesson JW; Johnell K
Article: ALZHEIMERS & DEMENTIA. 2025;21(3):e70081
Commonly prescribed multi-medication therapies exert sex-specific effects on Alzheimer's disease pathology and metabolomic profiles in App^NL-G-F mice: Implications for personalized therapeutics in aging
Eroli F; Johnell K; Acararicin Z; Tsagkogianni C; Zerial S; Lancia S; Latorre-Leal M; Alanko V; Hilmer SN; Matton A; Wastesson JW; Cedazo-Minguez A; Maioli S
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2025;:1500-1507
Antibiotic Use and Risk of Microscopic Colitis in Older Adults: A Nationwide Self-Controlled Case Series Study
Szilcz M; Wastesson JW; Bergman D; Johnell K; Ludvigsson JF
Article: EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2025;132:97-105
Comorbidity patterns and the risk of injurious falls in older people with atrial fibrillation: Findings from a Swedish nation-wide population-based study
Trevisan C; Damiano C; Dai L; Wastesson JW; Calderon-Larranaga A; Johnell K; Amrouch C; Onder G; Marengoni A; Proietti R; Lip GYH; Johnsen S; Petrovic M; Vetrano DL; AFFIRMO C
Article: ANNALS OF EPIDEMIOLOGY. 2024;98:1-7
Comparison of sociodemographic factors, healthcare utilisation by general practitioner visits, somatic hospital admissions, and medication use in Norway, Sweden, and Denmark
Bliddal M; Bjork E; Karlstad O; Wastesson JW; Wesselhoeft R; Lindahl-Jacobsen R; Pottegard A; Wensink MJ; Rasmussen L
Article: DRUGS & AGING. 2024;41(9):775-781
Trends in Drug Duplications in Swedish Older Adults: A Nationwide Register Study from 2006 to 2021
Erhan T; Wastesson JW; Fastbom J
Article: EUROPEAN GERIATRIC MEDICINE. 2024;15(4):1149-1158
Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort
Amrouch C; Amrouch S; Dai L; Calderon-Larranaga A; Wastesson JW; Johnell K; Vetrano DL; De Smedt D; Petrovic M
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2024;52(6):726-732
History of working conditions and the risk of old-age dependency: a nationwide Swedish register-based study
Nilsen C; Agerholm J; Kelfve S; Wastesson JW; Kareholt I; Nabe-Nielsen K; Meinow B
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2024;72(7):2048-2059
Spousal bereavement and four-year trajectories of medication use: A nationwide register-based study in Swedish older adults
Maura G; Blotiere P-O; Wastesson JW; Johnell K
Article: ECLINICALMEDICINE. 2024;73:102689
Comparative effectiveness of glucagon-like peptide-1 agonists, dipeptidyl peptidase-4 inhibitors, and sulfonylureas on the risk of dementia in older individuals with type 2 diabetes in Sweden: an emulated trial study
Tang B; Sjolander A; Wastesson JW; Maura G; Blotiere P-O; Szilcz M; Mak JKL; Qin C; Alvarsson M; Religa D; Johnell K; Hagg S
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2024;52(3):345-353
Long-term care use, hospitalizations and mortality during COVID-19 in Finland and Sweden: A nationwide register-based study in 2020
Blotiere P-O; Maura G; Raitanen J; Pulkki J; Forma L; Johnell K; Aaltonen M; Wastesson JW
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2024;72(2):456-466
Cholinesterase inhibitors and non-steroidal anti-inflammatory drugs and the risk of peptic ulcers: A self-controlled study
Szilcz M; Wastesson JW; Calderon-Larranaga A; Prieto-Alhambra D; Blotiere P-O; Maura G; Johnell K
Article: FRONTIERS IN PHARMACOLOGY. 2024;15:1476464
Potentially inappropriate prescribing in polymedicated older adults with atrial fibrillation and multimorbidity: a Swedish national register-based cohort study
Amrouch C; Vetrano DL; Damiano C; Dai L; Calderon-Larranaga A; Grymonprez M; Proietti M; Lip GYH; Johnsen SP; Wastesson JW; Johnell K; De Smedt D; Petrovic M
Journal article: CEREBRAL CIRCULATION - COGNITION AND BEHAVIOR. 2024;6:100309
Effects of multi-medication treatments including cardiovascular drugs in male and female APPNL-G-F knock in mice
Eroli F; Tsagkogianni C; Zerial S; Andersson F; Acararicin Z; Latorre-Leal M; Wastesson J; Cedazo-Minguez A; Johnell K; Maioli S
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2023;51(6):835-842
Increasing inequalities in disability-free life expectancy among older adults in Sweden 2002-2014
Sundberg L; Agahi N; Wastesson JW; Fritzell J; Fors S
Article: EUROPEAN JOURNAL OF AGEING. 2023;20(1):30
Length of the period with late life dependency: Does the age of onset make a difference?
Kelfve S; Wastesson JW; Meinow B
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2023;51(4):579-586
Educational differences in long-term care use in Sweden during the last two years of life
Kelfve S; Wastesson JW; Meinow B
Article: FRONTIERS IN PHARMACOLOGY. 2023;14:1030849
Regional variations in excessive polypharmacy and potentially inappropriate drug use among older adults in Sweden: Trends from 2006 to 2020
Wastesson JW; Fritzell J; Burstrom B; Johnell K; Fastbom J
Article: FRONTIERS IN ONCOLOGY. 2023;13:1223563
Endocrine treatment near the end of life among older women with metastatic breast cancer: a nationwide cohort study
Szilcz M; Wastesson JW; Calderon-Larranaga A; Morin L; Lindman H; Johnell K
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2023;132(1):60-70
Use of benzodiazepines and benzodiazepine-related drugs in the Nordic countries between 2000 and 2020
Hojlund M; Gudmundsson LS; Andersen JH; Saastamoinen LK; Zoega H; Skurtveit SO; Wastesson JW; Hallas J; Pottegard A
Article: ACTA ONCOLOGICA. 2022;61(12):1437-1445
Potential overtreatment in end-of-life care in adults 65 years or older dying from cancer: applying quality indicators on nationwide registries
Szilcz M; Wastesson JW; Morin L; Calderon-Larranaga A; Lambe M; Johnell K
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2022;50(5):593-600
Life-course trajectories of working conditions and successful ageing
Nilsen C; Darin-Mattsson A; Hyde M; Wastesson JW
Article: BMC PUBLIC HEALTH. 2022;22(1):759
Trends over two decades in life expectancy with complex health problems among older Swedes: implications for the provision of integrated health care and social care
Meinow B; Li P; Jasilionis D; Oksuzyan A; Sundberg L; Kelfve S; Wastesson JW
Article: DEMOGRAPHY. 2021;58(6):2117-2138
Growing Income-Based Inequalities in Old-Age Life Expectancy in Sweden, 2006-2015
Fors S; Wastesson JW; Morin L
Article: AGING-US. 2021;13(11):14729-14744
Long-term exposure to polypharmacy impairs cognitive functions in young adult female mice
Eroli F; Johnell K; Latorre-Leal M; Hilmer S; Wastesson J; Cedazo-Minguez A; Maioli S
Article: BMJ SUPPORTIVE & PALLIATIVE CARE. 2021;:bmjspcare-2020-002778-e961
Unplanned hospitalisations in older people: illness trajectories in the last year of life
Szilcz M; Wastesson JW; Johnell K; Morin L
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2020;21(6):799-805
Long -Term Care Use During the Last 2 Years of Life in Sweden: Implications for Policy to Address Increased Population Aging
Meinow B; Wastesson JW; Kareholt I; Kelfve S
Article: AGING-US. 2020;12(11):10147-10161
Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice
Eroli F; Johnell K; Leal ML; Adamo C; Hilmer S; Wastesson JW; Cedazo-Minguez A; Maioli S
Article: PALLIATIVE MEDICINE. 2019;33(8):1080-1090
How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study
Morin L; Wastesson JW; Laroche M-L; Fastbom J; Johnell K
Article: CANCER. 2019;125(13):2309-2317
Preventive drugs in the last year of life of older adults with cancer: Is there room for deprescribing?
Morin L; Todd A; Barclay S; Wastesson JW; Fastbom J; Johnell K
Article: CLINICAL EPIDEMIOLOGY. 2019;11:483-493
Polypharmacy and injurious falls in older adults: a nationwide nested case-control study
Morin L; Larranaga AC; Welmer A-K; Rizzuto D; Wastesson JW; Johnell K
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2019;74(5):742-747
Is Who you Ask Important? Concordance Between Survey and Registry Data on Medication Use Among Self- and Proxy-Respondents in the Longitudinal Study of Aging Danish Twins and the Danish 1905-Cohort Study
Oksuzyan A; Sauer T; Gampe J; Hoehn A; Wod M; Christensen K; Wastesson JW
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2019;67(3):455-462
How Chronic Is Polypharmacy in Old Age? A Longitudinal Nationwide Cohort Study.
Wastesson JW; Morin L; Laroche M-L; Johnell K
Article: PHARMACOTHERAPY. 2019;39(2):150-160
Nonaspirin Nonsteroidal Antiinflammatory Drug Use in the Nordic Countries from a Cardiovascular Risk Perspective, 2000-2016: A Drug Utilization Study
Kristensen KB; Karlstad O; Martikainen JE; Pottegard A; Wastesson JW; Zoega H; Schmidt M
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2018;123(3):301-307
Trends in Use of Paracetamol in the Nordic Countries
Wastesson JW; Martikainen JE; Zoega H; Schmidt M; Karlstad O; Pottegard A
Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2018;72(6):526-531
Gender differences in the use of anti-infective medications before and after widowhood: a register-based study
Santacroce A; Wastesson JW; Hoehn A; Christensen K; Oksuzyan A
Article: CLINICAL EPIDEMIOLOGY. 2018;10:289-298
The epidemiology of polypharmacy in older adults: register-based prospective cohort study
Morin L; Johnell K; Laroche M-L; Fastbom J; Wastesson JW
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(3):193-199
Research Priorities for Optimizing Geriatric Pharmacotherapy: An International Consensus
Tan ECK; Sluggett JK; Johnell K; Onder G; Elseviers M; Morin L; Vetrano DL; Wastesson JW; Fastbom J; Taipale H; Tanskanen A; Bell JS
Article: PALLIATIVE MEDICINE. 2018;32(2):366-375
Is the level of education associated with transitions between care settings in older adults near the end of life? A nationwide, retrospective cohort study
Kelfve S; Wastesson J; Fors S; Johnell K; Morin L
Article: PLOS ONE. 2018;13(3):e0194892
The composition of polypharmacy: A register-based study of Swedes aged 75 years and older
Wastesson JW; Minguez AC; Fastbom J; Maioli S; Johnell K
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2017;26(2):152-161
Drug use among complete responders, partial responders and non-responders in a longitudinal survey of nonagenarians: analysis of prescription register data
Wastesson JW; Rasmussen L; Oksuzyan A; Hallas J; Christensen K; Pottegard A
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2017;65(1):160-164
Changes in Drug Use and Polypharmacy After the Age of 90: A Longitudinal Study of the Danish 1905 Cohort
Wastesson JW; Oksuzyan A; Hjelmborg JVB; Christensen K
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2016;17(1):31-35
Remaining Life Expectancy With and Without Polypharmacy: A Register-Based Study of Swedes Aged 65 Years and Older
Wastesson JW; Canudas-Romo V; Lindahl-Jacobsen R; Johnell K
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2015;132(1):20-28
Educational disparities in antipsychotic drug use among older people with and without dementia in Sweden
Wastesson JW; Weitoft GR; Johnell K
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2014;24(6):991-996
Socioeconomic inequalities in access to specialized psychotropic prescribing among older Swedes: a register-based study
Wastesson JW; Fastbom J; Weitoft GR; Fors S; Johnell K
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2014;42(8):795-803
Inequalities in health care use among older adults in Sweden 1992-2011: A repeated cross-sectional study of Swedes aged 77 years and older
Wastesson JW; Fors S; Parker MG; Johnell K
Article: OSTEOPOROSIS INTERNATIONAL. 2013;24(2):433-442
Educational level and use of osteoporosis drugs in elderly men and women: a Swedish nationwide register-based study
Wastesson JW; Weitoft GR; Parker MG; Johnell K
Article: EUROPEAN JOURNAL OF AGEING. 2013;10(4):271-277
The rise and fall of women's advantage: a comparison of national trends in life expectancy at age 65 years
Thorslund M; Wastesson JW; Agahi N; Lagergren M; Parker MG
Article: AGE AND AGEING. 2012;41(2):218-224
Drug use in centenarians compared with nonagenarians and octogenarians in Sweden: a nationwide register-based study
Wastesson JW; Parker MG; Fastbom J; Thorslund M; Johnell K
Article: JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES. 2011;66(3):287-291
Indicators of Job Strain at Midlife and Cognitive Functioning in Advanced Old Age
Andel R; Crowe M; Kareholt I; Wastesson J; Parker MG
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All other publications

Letter: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2025;:1549-1550
Editorial: Association of Antibiotic Exposure With Microscopic Colitis-Authors' Reply
Szilcz M; Wastesson JW; Bergman D; Johnell K; Ludvigsson JF
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2024;72(11):3612-3613
Reply to: Peptic ulcers with ChEIs, NSAIDs
Szilcz M; Wastesson JW; Calderon-Larranaga A; Prieto-Alhambra D; Blotiere P-O; Maura G; Johnell K
Preprint: MEDRXIV. 2024
Trends of use of drugs with suggested shortages and their alternatives across 52 real world data sources and 18 countries in Europe and North America
Pineda-Moncusí M; Rekkas A; Pérez ÁM; Leis A; Gomez CL; Fey E; Bruninx E; Maljković F; Sánchez-Sáez F; Rodeiro J; Kiss LZ; Franz M; Mayer M-A; Eleangovan N; Pau PP; Natsiavas P; Şen S; Cooper S; Reisberg S; Manlik K; del Pino B; Uribe AP; Üresin AY; Bastić AD; Rodrigues AM; Afonso Ã; Palomar-Cros A; Verbiest A; Delmestri A; Erdoğan B; Dinkel-Keuthage C; Torre CO; de Beukelaar C; Eteve-Pitsaer C; Gonçalves CF; de Palma C; Gavina C; Dedman D; Price DB; Balan DG; Enders D; Burn E; Henke E; Scheurwegs E; Callewaert E; Martínez EP; Tan EH; Prasser F; Antonini F; Staelens F; Nyberg F; Agard G; Galli G; Candore G; Mestdach G; Shachaf H; Rantala H; Li H; Reinecke I; López-Sánchez I; Poquet-Jornet JE; de la Cruz Bertolo J; Evers J; Firmino-Machado J; Wastesson J; Bermúdez JLC; Ramírez-Anguita JM; Porkka K; Johnell K; Boyer L; Cool L; Moscetti L; Merkelbach M; Canelas-Pais M; Dominici M; Szilcz M; Puntoni M; Mosseveld M; Tadrous M; Oltra-Sastre M; Bové M; Rappoport N; Barrio NG; Ettala O; Baili P; Mayo PR; Prinsen P; Norris R; Claire R; Yackob RS; Lillini R; Garcia-Torrens S; Kukkurainen S; Lazzarelli S; Duarte-Salles T; Taveira-Gomes T; Jansen T; Keilholz U; Man WY; Li X; Bagyura Z; Prieto-Alhambra D; Rijnbeek PR; Burkard T
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2024;33:255
Antibiotic Use and Risk of Microscopic Colitis in Older Adults: A Nationwide Self-Controlled Case Series Study
Szilcz M; Ludvigsson JF; Johnell K; Wastesson JW
Review: HEALTHCARE TECHNOLOGY LETTERS. 2023;10(3):62-72
Feasibility study of a clinical decision support system for polymedicated patients in primary care
Manzanet JMP; Fico G; Merino-Barbancho B; Hernandez L; Vera-Munoz C; Seara G; Torrego M; Gonzalez H; Wastesson J; Fastbom J; Mayol J; Johnell K; Gomez-Gascon T; Arredondo MT
Conference publication: GASTROENTEROLOGY. 2023;164(6):S226
MEDICATIONS AND RISK OF MICROSCOPIC COLITIS: A NATIONWIDE COHORT STUDY
Khalili H; Roelstraete B; Johnell K; Schneeweiss S; Wastesson JW; Ludvigsson JF
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2023;32:25
Use of cholinesterase inhibitors and non-steroidal anti-inflammatory drugs and the risk of peptic ulcers: A population-based self-controlled case series study
Szilcz M; Wastesson J; Calderon-Larranaga A; Prieto-Alhambra D; Blotiere P-O; Maura G; Johnell K
Conference publication: INNOVATION IN AGING. 2022;6:502-503
HISTORY OF JOB STRAIN AND RISK OF LATE-LIFE DEPENDENCY: A NATIONWIDE SWEDISH REGISTERBASED STUDY
Kareholt I; Nilsen C; Agerholm J; Kelfve S; Wastesson J; Nabe-Nielsen K; Meinow B
Preprint: AUTHOREA. 2022
FEASIBILITY STUDY OF A CLINICAL DECISION SUPPORT SYSTEM FOR POLYMEDICATED PATIENTS IN PRIMARY CARE
Manzanet JMP; Fico G; Merino-Barbancho B; Vera-Muñoz C; Hernandez L; Seara G; Torrego M; Gonzalez H; Wastesson J; Fastbom J; Mayol J; Johnell K; Gómez T; Arredondo MT
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2022;31:111
End-of-life endocrine treatment of older hormone receptor-positive metastatic breast cancer patients: A nationwide Swedish retrospective cohort study
Szilcz M; Wastesson J; Lindman H; Johnell K
Preprint: MEDRXIV. 2020
Spousal bereavement, mortality and risk of negative health outcomes among older adults: a population-based study
Morin L; Wastesson JW; Fors S; Agahi N; Johnell K
Letter: CANCER. 2019;125(19):3471-3472
Reply to Deprescription during last year of life in patients with pancreatic cancer: Optimization or nihilism?
Morin L; Wastesson JW; Johnell K; Barclay S; Todd A
Review: EXPERT OPINION ON DRUG SAFETY. 2018;17(12):1185-1196
An update on the clinical consequences of polypharmacy in older adults: a narrative review
Wastesson JW; Morin L; Tan ECK; Johnell K
Letter: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2016;17(10):957-958
Expanding the Proportion of Life With Polypharmacy in Sweden: 2006-2013
Wastesson JW; Fastbom J; Johnell K
Doctoral thesis: 2014
Unequal drug treatment : age and educational differences among older adults
Wastesson J

Grants

Research programme on Ageing, Loneliness, and Mental health: understanding the connections and enabling change (REALM)
Swedish Research Council for Health Working Life and Welfare
1 July 2023 - 30 June 2029
Suicide risks, self-harm and loneliness among older adults: the influence of medications, bereavement and dementia
Swedish Research Council for Health Working Life and Welfare
1 July 2023 - 30 June 2026
Medicinreduktion för äldre personer: kartläggning av den nuvarande situationen och framtida implementering
Swedish Research Council for Health Working Life and Welfare
1 January 2023 - 31 December 2025
The most severely affected in the COVID-19 pandemic: older adults’ risk profiles, medications, long-term consequences and vaccination in large nationwide data
Swedish Research Council
1 December 2021 - 30 November 2025
Post-COVID in the most severely affected in the pandemic: older adults’ risk factors, medications and outcomes in large nationwide data
Swedish Research Council
1 December 2021 - 30 November 2025
Place of death in older adults during the Covid-19 pandemic: A systematic review
Swedish Research Council for Health Working Life and Welfare
1 December 2020 - 30 November 2021
Until death do us part? Impact of spousal bereavement on health and mortality among older adults
Swedish Research Council for Health Working Life and Welfare
1 January 2020 - 31 December 2022
Too much, too late? Use of overly aggressive treatments during the last months of life of older adults with poor prognosis
Swedish Research Council for Health Working Life and Welfare
1 January 2019 - 31 December 2021
Inequality dynamics over the life course: family and policy influences
Swedish Research Council for Health Working Life and Welfare
1 January 2017 - 31 December 2022
Longer lives, healthier lives? Patterns of severe health problems and dependency in the last years of life
Swedish Research Council for Health Working Life and Welfare
1 January 2017 - 31 December 2019
Longer lives, healthier lives? Patterns of severe health problems and dependency in the last years of life
Swedish Research Council
1 January 2017 - 31 December 2019

Employments

Senior Research Specialist, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2021-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2014

About me

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Articles

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Degrees and Education

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