John Inge Johnsen
Principal Researcher | Docent
E-mail: john.inge.johnsen@ki.se
Visiting address: Widerströmska huset, hiss 1, plan 8 Tomtebodavägen 18A, 17177 Stockholm
Postal address: K6 Kvinnors och barns hälsa, K6 Barnonkologi och Barnkirurgi Kogner/Johnsen, 171 77 Stockholm
About me
- Dr. John Inge Johnsen received his PhD diploma at University of Tromsö,
Norway under the supervision of Professor Terje Traavik in 1994. His thesis
focused on the characterization of regulatory genetic elements in
polyomaviruses and the effects these regulatory regions have on host/virus
interaction.
After finishing his PhD, Dr. Johnsen went on to pursue his main scientific
interest - cancer biology, oncogenes and tumor suppressor genes and 1995 he
joined Professor Eric Stanbridge´s research group at University of
California, Irvine where he studied the effects of p53 and genes regulated by
p53 on cancer development.
After spending two years at the University of Tromsö as an assistant
professor/lecturer Dr. Johnsen joined professor Per Kogner´s research group
at Karolinska Institutet as a postdoctoral fellow where he together with Dr.
Kogner built up the childhood neural tumor research consortium.
Dr. Johnsen became Associate professor at Karolinska Instituet in 2010.
1984-1990 Msc, University of Tromsö, Norway
1991-1994 PhD, University of Tromsö, Norway
1995-1997 Postdoc, Dr.Stanbridge´s lab, University of California, Irvine,
USA
1997-1998 Postdoc, Dept. of Pediatrics, University of Tromsö Norway
2001-2003 Postdoc, Childhood Cancer Research Unit, Karolinska Istitutet
Research
- The main focus of our research group is to search for new treatment options
that lead to better survival, less treatment-related complications and better
quality of life for children with medulloblastoma and neuroblastoma. This is
done by applying different Omic techniques to characterize the molecular
landscape of malignant and corresponding non-cancerous cells within the tumor
microenvironment and to use a translational approach applying preclinical in
vivo models to characterize the anti-tumorigenic effects of drugs and
compounds targeting specific biological aberrations in cancer cells or
populations of cells located within the tumor microenvironment.
Articles
- Article: CANCER LETTERS. 2024;605:217261
- Journal article: CANCER RESEARCH. 2024;84(17):b060
- Article: MOLECULAR CANCER. 2024;23(1):180
- Article: NUCLEIC ACIDS RESEARCH (NAR). 2024;52(5):2648-2671
- Article: CANCERS. 2024;16(4):812
- Article: JCI INSIGHT. 2024;9(6):e173337
- Article: GENOME MEDICINE. 2024;16(1):1
- Article: CANCERS. 2023;15(18):4599
- Journal article: NEURO-ONCOLOGY. 2023;25(Suppl 1):i62MDB-04. SINGLE-CELL TRANSCRIPTOMIC ANALYSIS REVEALS DISTINCT GENOMIC LANDSCAPES, CELL TRAJECTORIES, AND TUMOUR-MICROENVIRONMENT INTERACTIONS IN FOUR SUBTYPES OF MEDULLOBLASTOMA
- Article: BRITISH JOURNAL OF CANCER. 2022;127(11):2060-2071
- Article: JCI INSIGHT. 2022;7(17):e153836
- Article: CELL REPORTS MEDICINE. 2022;3(6):100657
- Journal article: CANCER RESEARCH. 2022;82(12_Supplement):1677
- Journal article: CANCER RESEARCH. 2022;82(12_Supplement):6215
- Article: LIFE SCIENCES. 2022;295:120394
- Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(3):182-201
- Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(7):3702
- Article: NATURE COMMUNICATIONS. 2022;13(1):1537
- Article: BMC GENOMICS. 2022;23(1):149
- Article: NEURO-ONCOLOGY ADVANCES. 2022;4(1):vdac028
- Article: CANCER DISCOVERY. 2021;11(12):3090-3105
- Article: CANCERS. 2021;13(23):6042
- Article: CANCERS. 2021;13(21):5493
- Article: CELL DEATH AND DISEASE. 2021;12(10):914
- Article: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS. 2021;169:102285
- Article: CANCER RESEARCH. 2021;81(6):1457-1471
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(33):20127-20138
- Article: THE FASEB JOURNAL. 2020;34(8):11101-11114
- Article: FRONTIERS IN ONCOLOGY. 2020;10:598872
- Article: CANCERS. 2019;12(1):E73-73
- Article: ONCOGENE. 2019;38(15):2800-2813
- Article: CANCERS. 2019;11(2):E202-202
- Article: CANCER LETTERS. 2019;442:341-350
- Article: EBIOMEDICINE. 2018;32:84-92
- Article: PHARMACOLOGICAL RESEARCH. 2018;131:164-176
- Article: ONCOTARGET. 2017;8(56):95135-95151
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(32):E6603-E6612
- Journal article: CANCER RESEARCH. 2017;77:687
- Journal article: CANCER RESEARCH. 2017;77:1945
- Article: SCIENTIFIC REPORTS. 2017;7:46366
- Article: CLINICAL CANCER RESEARCH. 2016;22(15):3849-3859
- Article: CELL REPORTS. 2016;16(4):979-993
- Article: BMC CANCER. 2016;16:490
- Journal article: CANCER RESEARCH. 2016;76:761
- Journal article: CANCER RESEARCH. 2016;76:2454
- Journal article: CANCER RESEARCH. 2016;76:2465
- Journal article: NEURO-ONCOLOGY. 2016;18(suppl_3):iii116
- Journal article: NEURO-ONCOLOGY. 2016;18(Suppl 3):iii116MB-83OMEGA-3 FATTY ACIDS DHA AND EPA SUPPRESS ONCOGENIC PGE2 IN MEDULLOBLASTOMA
- Article: BMC CANCER. 2016;16:259
- Article: MOLECULAR & CELLULAR ONCOLOGY. 2016;3(2):e1131356
- Article: DEVELOPMENTAL CELL. 2016;36(2):164-178
- Article: ONCOIMMUNOLOGY. 2016;5(12):e1232222
- Article: NATURE COMMUNICATIONS. 2015;6:8904
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(26):8070-8075
- Article: JOURNAL OF NEURO-ONCOLOGY. 2015;123(1):1-13
- Journal article: LINDBERGIA. 2015;38(1):30-38
- Article: BMC CANCER. 2014;14:600
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;450(4):1600-1605
- Article: CANCER DISCOVERY. 2014;4(4):434-451
- Article: JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2014;106(3):djt459
- Journal article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2014;2(Suppl 3):p203
- Article: PLOS ONE. 2014;9(4):e95628
- Article: INTERNATIONAL JOURNAL OF CANCER. 2013;133(10):2351-2361
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2013;43(3):831-838
- Journal article: CANCER RESEARCH. 2013;73(8_Supplement):2751
- Journal article: CANCER RESEARCH. 2013;73(8_Supplement):2746
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2013;42(4):1239-1248
- Article: INTERNATIONAL JOURNAL OF CANCER. 2013;132(7):1516-1524
- Article: BMC MEDICAL GENETICS. 2012;13:83
- Article: BRITISH JOURNAL OF CANCER. 2012;106(11):1807-1815
- Article: PLOS ONE. 2012;7(1):e29331
- Article: PLOS ONE. 2012;7(12):e51297
- Article: ONCOTARGET. 2011;2(12):1329-1338
- Article: INTERNATIONAL JOURNAL OF CANCER. 2011;129(12):2958-2965
- Article: CANCER LETTERS. 2011;310(2):222-231
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2011;121(10):4043-4055
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;411(1):208-212
- Article: INTERNATIONAL JOURNAL OF CANCER. 2011;128(7):1703-1711
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2011;38(3):843-849
- Article: CELL CYCLE. 2010;9(13):2548-2554
- Journal article: CANCER RESEARCH. 2010;70(8_Supplement):4354
- Article: THE FASEB JOURNAL. 2010;24(3):906-915
- Journal article: ECANCERMEDICALSCIENCE. 2010;4:156
- Article: CANCER RESEARCH. 2010;70(1):266-276
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(44):18757-18762
- Article: INTERNATIONAL JOURNAL OF CANCER. 2009;124(5):1227-1234
- Article: NEURO-ONCOLOGY. 2008;10(5):661-674
- Article: THE FASEB JOURNAL. 2008;22(10):3525-3536
- Article: ONCOGENE. 2008;27(20):2910-2922
- Article: MOLECULAR CANCER THERAPEUTICS. 2007;6(9):2409-2417
- Article: CLINICAL CANCER RESEARCH. 2007;13(3):1036-1044
- Article: INTERNATIONAL JOURNAL OF CANCER. 2006;119(3):493-500
- Article: INTERNATIONAL JOURNAL OF CANCER. 2006;118(10):2584-2593
- Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2004;25(6):1849-1857
- Article: CANCER RESEARCH. 2004;64(20):7210-7215
- Article: JOURNAL OF MEDICAL VIROLOGY. 2003;70(1):14-19
- Article: INTERNATIONAL JOURNAL OF CANCER. 2003;104(4):418-424
- Article: ANTICANCER RESEARCH. 2001;21(6A):3733-3738
- Article: INTERNATIONAL JOURNAL OF CANCER. 2000;88(5):685-691
- Article: CANCER RESEARCH. 1999;59(5):1160-1163
- Article: VIRUS RESEARCH. 1997;52(1):61-71
- Article: NUCLEIC ACIDS RESEARCH (NAR). 1996;24(11):2158-2165
- Article: JOURNAL OF GENERAL VIROLOGY. 1995;76:1571-1581
- Journal article: JOURNAL OF IMMUNOLOGICAL METHODS. 1994;173(2):149-156
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All other publications
- Review: CANCERS. 2024;16(10):1863
- Preprint: BIORXIV. 2024
- Conference publication: NEURO-ONCOLOGY. 2023;25:i62
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023
- Other: AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR). 2023
- Conference publication: CANCER SCIENCE. 2023;114:249
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2023;70:S107
- Review: CURRENT ONCOLOGY REPORTS. 2022;24(8):1053-1062
- Conference publication: CANCER RESEARCH. 2022;82(12)
- Conference publication: CANCER RESEARCH. 2022;82(12)
- Conference publication: CANCER RESEARCH. 2022;82(12)
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S230
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S226
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S211
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S227
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S229-S230
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S229
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2022;69:S211-S212
- Preprint: BIORXIV. 2021
- Preprint: BIORXIV. 2021
- Preprint: BIORXIV. 2020
- Preprint: BIORXIV. 2020
- Preprint: SSRN ELECTRONIC JOURNAL. 2020
- Review: FRONTIERS IN ONCOLOGY. 2020;10:624079
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2020;67:S3
- Review: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2019;12:9
- Conference publication: CANCER RESEARCH. 2018;78(13):4145
- Conference publication: CANCER RESEARCH. 2018;78(13):5092
- Review: EXPERT OPINION ON DRUG DISCOVERY. 2017;12(8):801-811
- Conference publication: CANCER RESEARCH. 2017;77:5832
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2017;64:S343
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2017;64:S232
- Conference publication: NEURO-ONCOLOGY. 2016;18:116
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2016;63:S28
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2016;63:S82
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2016;63:S82-S83
- Conference publication: CANCER RESEARCH. 2015;75:3279
- Conference publication: CANCER RESEARCH. 2015;75:3283
- Conference publication: CANCER RESEARCH. 2015;75:1632
- Conference publication: CANCER RESEARCH. 2015;75:503
- Conference publication: CANCER RESEARCH. 2015;75:3275
- Conference publication: CANCER RESEARCH. 2015;75:3266
- Review: WORLD JOURNAL OF EXPERIMENTAL MEDICINE. 2015;5(1):1-10
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2015;62:S332
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2015;62:S328-S329
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2015;62:S149
- Meeting abstract: EUROPEAN JOURNAL OF CANCER. 2014;50:135
- Conference publication: CANCER RESEARCH. 2014;74(20):a84
- Conference publication: CANCER RESEARCH. 2014;74(19):3976
- Conference publication: CANCER RESEARCH. 2014;74(19):3986
- Conference publication: CANCER RESEARCH. 2014;74(19):3971
- Conference publication: CANCER RESEARCH. 2014;74(19):3988
- Meeting abstract: CANCER RESEARCH. 2014;74(19):3110
- Letter: BRITISH JOURNAL OF CANCER. 2013;108(10):2191
- Meeting abstract: CANCER RESEARCH. 2013;73(8):3795
- Conference publication: CANCER RESEARCH. 2013;73(8):3817
- Conference publication: NEURO-ONCOLOGY. 2013;15:18
- Editorial comment: ONCOIMMUNOLOGY. 2012;1(5):739-740
- Conference publication: CANCER RESEARCH. 2012;72:1420
- Conference publication: CANCER RESEARCH. 2012;72:4725
- Conference publication: CANCER RESEARCH. 2012;72:825
- Conference publication: CANCER RESEARCH. 2012;72:2499
- Conference publication: NEURO-ONCOLOGY. 2012;14:102
- Conference publication: NEURO-ONCOLOGY. 2012;14:99-100
- Conference publication: CANCER RESEARCH. 2011;71:lb-209-lb-209
- Conference publication: NEURO-ONCOLOGY. 2011;13:I9
- Review: EXPERIMENTAL CELL RESEARCH. 2010;316(8):1365-1373
- Corrigendum: CANCER RESEARCH. 2010;70(5):2138-2139
- Review: ADVANCES IN CANCER RESEARCH. 2010;107:163-224
- Review: APOPTOSIS : AN INTERNATIONAL JOURNAL ON PROGRAMMED CELL DEATH. 2009;14(4):424-438
- Conference publication: CANCER RESEARCH. 2009;69
- Conference publication: CANCER RESEARCH. 2009;69
- Conference publication: CANCER RESEARCH. 2009;69
- Conference publication: PEDIATRIC BLOOD AND CANCER. 2009;53(5):807
- Conference publication: NEURO-ONCOLOGY. 2008;10(3):506
- Meeting abstract: CYTOKINE. 2007;39(1):33
- Conference publication: NEURO-ONCOLOGY. 2007;9(2):197
- Conference publication: CANCER RESEARCH. 2006;66(8)
- Conference publication: CANCER RESEARCH. 2006;66(8)
- Conference publication: CANCER RESEARCH. 2006;66(8)
- Conference publication: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2006;79(1-2):185
- Review: CANCER LETTERS. 2005;228(1-2):195-201
- Review: CANCER LETTERS. 2005;228(1-2):247-255
- Published conference paper: PEDIATRIC BLOOD AND CANCER. 2000;35(6):593-596
- Review: VIRUS GENES. 1995;10(3):261-275
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Grants
- Barncancerfonden1 January 2023 - 31 December 2023
- Swedish Cancer Society1 January 2022
- New therapy for medulloblastoma and neuroblastomaSwedish Cancer Society1 January 2018
- New therapy for medulloblastoma and neuroblastomaSwedish Cancer Society1 January 2017
- New therapy for medulloblastoma and neuroblastomaSwedish Cancer Society1 January 2016
- Novel Neuroblastoma Biomarkers of Clinical RelevanceSwedish Foundation for Strategic Research1 January 2015 - 31 December 2019
- New therapy for medulloblastoma and neuroblastomaSwedish Cancer Society1 January 2015
- Targeted therapy for children with medulloblastomaSwedish Cancer Society1 January 2014
- Swedish Research Council1 January 2009 - 31 December 2011
Employments
- Principal Researcher, Department of Women's and Children's Health, Karolinska Institutet, 2022-
Degrees and Education
- Docent, Karolinska Institutet, 2010