Johan Ericson

About me
Publications
CV
Public outreach and news

About me

Professor of Developmental Biology.

Research

I'm focusing on stem cells and neural development. My reserach group is
presented here.

Articles

Article: NATURE COMMUNICATIONS. 2022;13(1):3046
Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery
Alekseenko Z; Dias JM; Adler AF; Kozhevnikova M; van Lunteren JA; Nolbrant S; Jeggari A; Vasylovska S; Yoshitake T; Kehr J; Carlen M; Alexeyenko A; Parmar M; Ericson J
Article: SCIENCE ADVANCES. 2020;6(38):eaba8196
A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells
Dias JM; Alekseenko Z; Jeggari A; Boareto M; Vollmer J; Kozhevnikova M; Wang H; Matise MP; Alexeyenko A; Iber D; Ericson J
Article: EMBO REPORTS. 2018;19(11):e46635
Sequentially acting SOX proteins orchestrate astrocyte- and oligodendrocyte-specific gene expression
Klum S; Zaouter C; Alekseenko Z; Bjorklund AK; Hagey DW; Ericson J; Muhr J; Bergsland M
Article: NUCLEIC ACIDS RESEARCH (NAR). 2018;46(W1):W163-W170
EviNet: a web platform for network enrichment analysis with flexible definition of gene sets
Jeggari A; Alekseenko Z; Petrov L; Dias JM; Ericson J; Alexeyenko A
Article: DEVELOPMENTAL BIOLOGY. 2017;429(1):132-146
Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model
Hoelzl MA; Heby-Henricson K; Gerling M; Dias JM; Kuiper RV; Trunkle C; Bergstrom A; Ericson J; Toftgard R; Teglund S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(30):E4387-E4396
Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons
Doucet-Beaupre H; Gilbert C; Profes MS; Chabrat A; Pacelli C; Giguere N; Rioux V; Charest J; Deng Q; Laguna A; Ericson J; Perlmann T; Ang S-L; Cicchetti F; Parent M; Trudeau L-E; Levesque M
Article: DEVELOPMENT. 2016;143(14):2616-2628
The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2
Gross S; Garofalo DC; Balderes DA; Mastracci TL; Dias JM; Perlmann T; Ericson J; Sussel L
Article: SCIENTIFIC REPORTS. 2016;6:26448
Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors
Hedlund E; Belnoue L; Theofilopoulos S; Salto C; Bye C; Parish C; Deng Q; Kadkhodaei B; Ericson J; Arenas E; Perlmann T; Simon A
Article: NATURE NEUROSCIENCE. 2015;18(6):826-835
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease
Laguna A; Schintu N; Nobre A; Alvarsson A; Volakakis N; Jacobsen JK; Gomez-Galan M; Sopova E; Joodmardi E; Yoshitake T; Deng Q; Kehr J; Ericson J; Svenningsson P; Shupliakov O; Perlmann T
Article: NEURON. 2015;85(3):497-504
A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors
Mattar P; Ericson J; Blackshaw S; Cayouette M
Article: PLOS ONE. 2015;10(4):e0124408
Nkx2.2 and Nkx2.9 Are the Key Regulators to Determine Cell Fate of Branchial and Visceral Motor Neurons in Caudal Hindbrain
Jarrar W; Dias JM; Ericson J; Arnold H-H; Holz A
Article: NEURON. 2014;84(5):927-939
Tgfβ Signaling Regulates Temporal Neurogenesis and Potency of Neural Stem Cells in the CNS
Dias JM; Alekseenko Z; Applequist JM; Ericson J
Article: CELL REPORTS. 2014;8(4):1018-1025
Sox6 and Otx2 Control the Specification of Substantia Nigra and Ventral Tegmental Area Dopamine Neurons
Panman L; Papathanou M; Laguna A; Oosterveen T; Volakakis N; Acampora D; Kurtsdotter I; Yoshitake T; Kehr J; Joodmardi E; Muhr J; Simeone A; Ericson J; Perlmann T
Article: CELL REPORTS. 2014;8(3):665-670
CtBPs Sense Microenvironmental Oxygen Levels to Regulate Neural Stem Cell State
Dias JM; Ilkhanizadeh S; Karaca E; Duckworth JK; Lundin V; Rosenfeld MG; Ericson J; Hermanson O; Teixeira AI
Article: STEM CELLS. 2014;32(3):609-622
Transcription Factor-Induced Lineage Programming of Noradrenaline and Motor Neurons from Embryonic Stem Cells
Mong J; Panman L; Alekseenko Z; Kee N; Stanton LW; Ericson J; Perlmann T
Article: STEM CELLS AND DEVELOPMENT. 2014;23(1):5-15
Detailed Expression Analysis of Regulatory Genes in the Early Developing Human Neural Tube
Marklund U; Alekseenko Z; Andersson E; Falci S; Westgren M; Perlmann T; Graham A; Sundstrom E; Ericson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(18):7330-7335
SoxB1-driven transcriptional network underlies neural-specific interpretation of morphogen signals
Oosterveen T; Kurdija S; Enstero M; Uhde CW; Bergsland M; Sandberg M; Sandberg R; Muhr J; Ericson J
Article: DEVELOPMENTAL CELL. 2012;23(5):1006-1019
Mechanistic Differences in the Transcriptional Interpretation of Local and Long-Range Shh Morphogen Signaling
Oosterveen T; Kurdija S; Alekseenko Z; Uhde CW; Bergsland M; Sandberg M; Andersson E; Dias JM; Muhr J; Ericson J
Article: DEVELOPMENT. 2012;139(14):2625-2634
Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors
Metzakopian E; Lin W; Salmon-Divon M; Dvinge H; Andersson E; Ericson J; Perlmann T; Whitsett JA; Bertone P; Ang S-L
Article: DEVELOPMENT. 2011;138(17):3711-3721
Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS
Wang H; Lei Q; Oosterveen T; Ericson J; Matise MP
Article: DEVELOPMENT. 2011;138(16):3399-3408
Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development
Deng Q; Andersson E; Hedlund E; Alekseenko Z; Coppola E; Panman L; Millonig JH; Brunet J-F; Ericson J; Perlmann T
Article: CELL STEM CELL. 2011;8(6):663-675
Transcription Factor-Induced Lineage Selection of Stem-Cell-Derived Neural Progenitor Cells
Panman L; Andersson E; Alekseenko Z; Hedlund E; Kee N; Mong J; Uhde CW; Deng Q; Sandberg R; Stanton LW; Ericson J; Perlmann T
Article: DEVELOPMENT. 2010;137(24):4249-4260
The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance
Holz A; Kollmus H; Ryge J; Niederkofler V; Dias J; Ericson J; Stoeckli ET; Kiehn O; Arnold H-H
Article: DEVELOPMENT. 2010;137(23):4051-4060
A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning
Lek M; Dias JM; Marklund U; Uhde CW; Kurdija S; Lei Q; Sussel L; Rubenstein JL; Matise MP; Arnold H-H; Jessell TM; Ericson J
Article: JOURNAL OF CELL SCIENCE. 2010;123(17):2931-2942
Control of Notch-ligand endocytosis by ligand-receptor interaction
Hansson EM; Lanner F; Das D; Mutvei A; Marklund U; Ericson J; Farnebo F; Stumm G; Stenmark H; Andersson ER; Lendahl U
Article: NATURE NEUROSCIENCE. 2010;13(9):1066-1074
Hindbrain interneurons and axon guidance signaling critical for breathing
Bouvier J; Thoby-Brisson M; Renier N; Dubreuil V; Ericson J; Champagnat J; Pierani A; Chedotal A; Fortin G
Article: DEVELOPMENT. 2010;137(3):437-445
Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression
Marklund U; Hansson EM; Sundstrom E; de Angelis MH; Przemeck GKH; Lendahl U; Muhr J; Ericson J
Article: SCIENCE SIGNALING. 2009;2(95):ra70
The Rfx4 Transcription Factor Modulates Shh Signaling by Regional Control of Ciliogenesis
Ashique AM; Choe Y; Karlen M; May SR; Phamluong K; Solloway MJ; Ericson J; Peterson AS
Article: DEVELOPMENT. 2009;136(15):2545-2555
Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain
Prakash N; Puelles E; Freude K; Truembach D; Omodei D; Di Salvio M; Sussel L; Ericson J; Sander M; Simeone A; Wurst W
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(18):7613-7618
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
Friling S; Andersson E; Thompson LH; Jonssonc ME; Hebsgaard JB; Nanou E; Alekseenko Z; Marklund U; Kjellander S; Volakakis N; Hovatta O; El Manira A; Bjorklund A; Perlmann T; Ericson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(9):3368-3373
Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
Zheng X; Linke S; Dias JM; Zheng X; Gradin K; Wallis TP; Hamilton BR; Gustafsson M; Ruas JL; Wilkins S; Bilton RL; Brismar K; Whitelaw ML; Pereira T; Gorman JJ; Ericson J; Peet DJ; Lendahl U; Poellinger L
Article: JOURNAL OF NEUROSCIENCE. 2008;28(4):963-975
Retrograde signaling onto Ret during motor nerve terminal maturation
Baudet C; Pozas E; Adameyko I; Andersson E; Ericson J; Ernfors P
Article: EXPERIMENTAL CELL RESEARCH. 2006;312(16):3108-3119
A global genomic transcriptional code associated with CNS-expressed genes
Bailey PJ; Klos JM; Andersson E; Karlen M; Kallstrom M; Ponjavic J; Muhr J; Lenhard B; Sandelin A; Ericson J
Article: DEVELOPMENTAL CELL. 2006;10(2):187-197
Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
Svärd J; Henricson KH; Persson-Lek M; Rozell B; Lauth M; Bergstrm Å; Ericson J; Toftgård R; Teglund S
Article: CELL. 2006;124(2):393-405
Identification of intrinsic determinants of midbrain dopamine neurons
Andersson E; Tryggvason U; Deng QL; Friling S; Alekseenko Z; Robert B; Perlmann T; Ericson J
Article: GENE EXPRESSION PATTERNS. 2006;6(2):162-170
Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development
Alanentalo T; Chatonnet F; Karlen M; Sulniute R; Ericson J; Andersson E; Ahlgren U
Article: DEVELOPMENTAL BIOLOGY. 2005;287(2):378-389
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
May SR; Ashique AM; Karlen M; Wang BL; Shen YG; Zarbalis K; Reiter J; Ericson J; Peterson AS
Article: NEURON. 2005;47(5):667-679
A Cxcl12-Cxcr4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons
Lieberam I; Agalliu D; Nagasawa T; Ericson J; Jessell TM
Article: DEVELOPMENT. 2005;132(13):3139-3149
NKX6 transcription factor activity is required for α- and β-cell development in the pancreas
Henseleit KD; Nellson SB; Kuhlbrodt K; Hennings JC; Ericson J; Sander M
Article: DEVELOPMENT. 2005;132(12):2697-2707
Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2
Singh MK; Christoffels VM; Dias JM; Trowe MO; Petry M; Schuster-Gossler K; Bürger A; Ericson J; Kispert A
Article: NEURON. 2005;45(1):55-67
Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain
Vallstedt A; Klos JM; Ericson J
Article: BMC GENOMICS. 2004;5(1):99
Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes -: art. no. 99
Sandelin A; Bailey P; Bruce S; Engström PG; Klos JM; Wasserman WW; Ericson J; Lenhard B
Article: DEVELOPMENT. 2004;131(16):4071-4083
Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins
Samad OA; Geisen MJ; Caronia G; Variet I; Zappavigna V; Ericson J; Goridis C; Rijli FM
Article: NATURE NEUROSCIENCE. 2003;6(9):933-938
Lmx1b is essential for the development of serotonergic neurons
Ding YQ; Marklund U; Yuan WL; Yin J; Wegman L; Ericson J; Deneris E; Johnson RL; Chen ZF
Article: DEVELOPMENT. 2003;130(17):4149-4159
Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain
Pattyn A; Vallstedt A; Dias JM; Sander M; Ericson J
Article: GENES & DEVELOPMENT. 2003;17(6):729-737
Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors
Pattyn A; Vallstedt A; Dias JM; Samad OA; Krumlauf R; Rijli FM; Brunet JF; Ericson J
Article: GENES & DEVELOPMENT. 2002;16(22):2865-2878
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
Persson M; Stamataki D; Welscher PT; Andersson E; Böse J; Rüther U; Ericson J; Briscoe J
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2001;18(6):649-663
Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem
Wallén Å; Castro DS; Zetterström RH; Karlén M; Olson L; Ericson J; Perlmann T
Article: NEURON. 2001;31(5):743-755
Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification
Vallstedt A; Muhr J; Pattyn A; Pierani A; Mendelsohn M; Sander M; Jessell TM; Ericson J
Article: CELL. 2001;104(6):861-873
Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
Muhr J; Andersson E; Persson M; Jessell TM; Ericson J
Article: GENES & DEVELOPMENT. 2000;14(17):2134-2139
Ventral neural patterning by Nkx homeobox genes:: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
Sander M; Paydar S; Ericson J; Briscoe J; Berber E; German M; Jessell TM; Rubenstein JLR
Article: CELL. 2000;101(4):435-445
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
Briscoe J; Pierani A; Jessell TM; Ericson J
Article: FEBS LETTERS. 1999;461(3):287-294
Cloning and DNA-binding properties of the rat pancreatic β-cell-specific factor Nkx6.1
Jorgensen MC; Petersen HV; Ericson J; Madsen OD; Serup P
Article: DEVELOPMENT. 1998;125(6):1005-1015
Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary.
Ericson J; Norlin S; Jessell TM; Edlund T
Article: CELL. 1995;81(5):747-756
Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube.
Ericson J; Muhr J; Placzek M; Lints T; Jessell TM; Edlund T
Show more

All other publications

Letter: DEVELOPMENT. 2016;143(10):1638-1640
Transcriptional interpretation of Shh morphogen signaling: computational modeling validates empirically established models
Uhde CW; Ericson J
Meeting abstract: MECHANISMS OF DEVELOPMENT. 2009;126:S245
Intrinsic transcriptional determinants promote efficient generation of neuronal subtypes from ES cells
Panman L; Andersson E; Hedlund E; Udhe C; Mong J; Alexsenko Z; Sandberg R; Ericson J; Perlmann T
Meeting abstract: DEVELOPMENTAL BIOLOGY. 2007;306(1):360
RFX4 transcription factor regulates IFT172 expression, cilia formation and dorsoventral patterning of the central nervous system
Ashique AM; Karlen M; Choe Y; Ericson J; Rubenstein JL; Peterson AS
Meeting abstract: DEVELOPMENTAL BIOLOGY. 2007;306(1):430
Temporal patterning determines visceral motoneuron subtypes generated from Nkx2.2⁺ progenitors in the hindbrain
Applequist JM; Karlen M; Jordi E; Perlmann T; Ericson J
Corrigendum: DEVELOPMENTAL CELL. 2006;10(3):409
Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway (vol 10, pg 187, 2006)
Svärd J; Heby-Henricson K; Persson-Lek M; Rozell B; Lauth M; Bergström A; Ericson J; Toftgård R; Teglund S
Review: CURRENT OPINION IN NEUROBIOLOGY. 2001;11(1):43-49
Specification of neuronal fates in the ventral neural tube
Briscoe J; Ericson J
Review: SEMINARS IN CELL AND DEVELOPMENTAL BIOLOGY. 1999;10(3):353-362
The specification of neuronal identity by graded sonic hedgehog signalling
Briscoe J; Ericson J

Employments

Professor, Department of Cell and Molecular Biology, Karolinska Institutet, 2006-

Degrees and Education

Docent, Karolinska Institutet, 2000

About me

Research

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI