Joëlle Pasman

About me
Publications
Grants
Public outreach and news

Research

My research focuses on the genetic epidemiology of (psychopathological)
behavior. I have finished a PhD in the genetics of substance use, and am now
working as a post doc on the genetics of (severe) major depressive disorder.

Articles

Journal article: SOCIAL SCIENCE AND MEDICINE. 2023;336:116254
Disentangling the interplay between genes, cognitive skills, and educational level in adolescent and young adult smoking - The TRAILS study
Schmengler H; Oldehinkel AJ; Vollebergh WAM; Pasman JA; Hartman CA; Stevens GWJM; Nolte IM; Peeters M
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(10):714-722
Genetic Contribution to the Heterogeneity of Major Depressive Disorder: Evidence From a Sibling-Based Design Using Swedish National Registers
Thuy-Dung N; Kowalec K; Pasman J; Larsson H; Lichtenstein P; Dalman C; Sullivan PF; Kuja-Halkola R; Lu Y
Article: THE LANCET REGIONAL HEALTH. EUROPE. 2023;29:100621
Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers
Pasman JA; Meijsen J; Haram M; Kowalec K; Harder A; Xiong Y; Nguyen T-D; Jangmo A; Shorter JR; Bergstedt J; Das U; Zetterberg R; Tate A; Lichtenstein P; Larsson H; Odsbu I; Werge T; Reichborn-Kjennerud T; Andreassen OA; Sullivan PF; Buil A; Tesli M; Lua Y
Journal article: DEVELOPMENT AND PSYCHOPATHOLOGY. 2023;35(1):396-409
Interplay between genetic risk and the parent environment in adolescence and substance use in young adulthood: A TRAILS study
Pasman JA; Smit K; Vollebergh WAM; Nolte IM; Hartman CA; Abdellaoui A; Verweij KJH; Maciejewski D; Vink JM
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e195
T50. THE CHALLENGES AND OPPORTUNITIES OF USING NATIONAL PATIENT REGISTERS FOR GENETICS RESEARCH: A DEPRESSION EXAMPLE
Meijsen J; Harder A; Nguyen T-D; Pasman J; Haram M; Shorter J; Mikkelsen DH; Zetterberg R; Lu Y; Plana-Ripoll O; Sullivan P; Werge T; Buil A
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e264-e265
A LARGE META-ANALYSIS ACROSS FOUR NORDIC COUNTRIES REVEALS SEVERAL SIGNIFICANT GENETIC ASSOCIATIONS FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER
Shorter J; Pasman J; Jangmo A; Kurvits S; Meijsen J; Frei O; Akdeniz BC; Andreassen O; Sullivan P; Werge T; Lehto K; Tesli M; Lu Y; Buil A; Consortium I
Journal article: BEHAVIOR GENETICS. 2022;52(4-5):306-314
The CADM2 Gene and Behavior: A Phenome-Wide Scan in UK-Biobank
Pasman JA; Chen Z; Smit DJA; Vink JM; Van Den Oever MC; Pattij T; De Vries TJ; Abdellaoui A; Verweij KJH
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):124
Genetics of age-at-onset in major depression
Harder A; Thuy-Dung N; Pasman JA; Mosing MA; Hagg S; Lu Y
Journal article: BEHAVIOR GENETICS. 2022;52(2):92-107
Genetic Risk for Smoking: Disentangling Interplay Between Genes and Socioeconomic Status
Pasman JA; Demange PA; Guloksuz S; Willemsen AHM; Abdellaoui A; ten Have M; Hottenga J-J; Boomsma DI; de Geus E; Bartels M; de Graaf R; Verweij KJH; Smit DJ; Nivard M; Vink JM
Journal article: EUROPEAN ADDICTION RESEARCH. 2022;28(3):176-185
Interactions between Genetic, Prenatal, Cortisol, and Parenting Influences on Adolescent Substance Use and Frequency: A TRAILS Study
Marceau K; Brick LA; Pasman JA; Knopik VS; Reijneveld SA
Journal article: ADDICTION BIOLOGY. 2021;26(6):e13015
Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study
Arends RM; Pasman JA; Verweij KJH; Derks EM; Gordon SD; Hickie I; Thomas NS; Aliev F; Zietsch BP; van der Zee MD; Mitchell BL; Martin NG; Dick DM; Gillespie NA; de Geus EJC; Boomsma DI; Schellekens AFA; Vink JM
Journal article: AMERICAN JOURNAL OF MEDICAL GENETICS, PART B: NEUROPSYCHIATRIC GENETICS. 2021;186(7):423-429
Investigating genetic correlation and causality between nicotine dependence andADHDin a broader psychiatric context
Vink JM; Treur JL; Pasman JA; Schellekens A
Journal article: DRUG AND ALCOHOL DEPENDENCE. 2020;214:108151
Causal relationships between substance use and insomnia
Pasman JA; Smit DJA; Kingma L; Vink JM; Treur JL; Verweij KJH
Journal article: NATURE NEUROSCIENCE. 2019;22(7):1196
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability (vol 21, pg 1161, 2018)
Pasman JA; Verweij KJH; Gerring Z; Stringer S; Sanchez-Roige S; Treur JL; Abdellaoui A; Nivard MG; Baselmans BML; Ong J-S; Ip HF; van der Zee MD; Bartels M; Day FR; Fontanillas P; Elson SL; de Wit H; Davis LK; MacKillop J; Derringer JL; Branje SJT; Hartman CA; Heath AC; van Lier PAC; Madden PAF; Magi R; Meeus W; Montgomery GW; Oldehinkel AJ; Pausova Z; Ramos-Quiroga JA; Paus T; Ribases M; Kaprio J; Boks MPM; Bell JT; Spector TD; Gelernter J; Boomsma DI; Martin NG; MacGregor S; Perry JRB; Palmer AA; Posthuma D; Munafo MR; Gillespie NA; Derks EM; Vink JM
Journal article: BEHAVIOR GENETICS. 2019;49(4):349-365
Systematic Review of Polygenic Gene-Environment Interaction in Tobacco, Alcohol, and Cannabis Use
Pasman JA; Verweij KJH; Vink JM
Journal article: NATURE NEUROSCIENCE. 2018;21(9):1161-1170
GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia
Pasman JA; Verweij KJH; Gerring Z; Stringer S; Sanchez-Roige S; Treur JL; Abdellaoui A; Nivard MG; Baselmans BML; Ong J-S; Ip HF; van der Zee MD; Bartels M; Day FR; Fontanillas P; Elson SL; de Wit H; Davis LK; MacKillop J; Derringer JL; Branje SJT; Hartman CA; Heath AC; van Lier PAC; Madden PAF; Maegi R; Meeus W; Montgomery GW; Oldehinkel AJ; Pausova Z; Ramos-Quiroga JA; Paus T; Ribases M; Kaprio J; Boks MPM; Bell JT; Spector TD; Gelernter J; Boomsma DI; Martin NG; MacGregor S; Perry JRB; Palmer AA; Posthuma D; Munafo MR; Gillespie NA; Derks EM; Vink JM

All other publications

Preprint: MEDRXIV. 2024;MEDRXIV
Causes and consequences of major depressive disorder: An encompassing Mendelian randomization study.
Pasman JA; Bergstedt J; Harder A; Gong T; Xiong Y; Hägg S; Fang F; Treur JL; Choi KW; Sullivan PF; Lu Y
Preprint: MEDRXIV. 2024;MEDRXIV
Distinct genomic signatures and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease.
Bergstedt J; Pasman JA; Ma Z; Harder A; Yao S; Parker N; Treur JL; Smit DJA; Frei O; Shadrin A; Meijsen JJ; Shen Q; Hägg S; Tornvall P; Buil A; Werge T; Hjerling-Leffler J; Als TD; Børglum AD; Lewis CM; McIntosh AM; Valdimarsdóttir UA; Andreassen OA; Sullivan PF; Lu Y; Fang F
Preprint: MEDRXIV. 2023;MEDRXIV
Associations of schizophrenia with arrhythmic disorders and electrocardiogram traits: an in-depth genetic exploration of population samples.
Treur JL; Thijssen AB; Smit DJ; Tadros R; Veeneman RR; Denys D; Vermeulen JM; Barc J; Bergstedt J; Pasman JA; Bezzina CR; Verweij KJH
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E32
THE GENETIC ARCHITECTURE OF MAJOR DEPRESSIVE DISORDER WITH SEVERE OUTCOME IN SCANDINAVIA
Tesli M; Shorter J; Jangmo A; Pasman J; Andreassen O; Sullivan P; Werge T; Lu Y; Demur AB
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E140
IS GENETIC RISK FOR EARLY ONSET MAJOR DEPRESSIVE DISORDER ASSOCIATED WITH MORE SEVERE CLINICAL FEATURES THAN BROAD MAJOR DEPRESSIVE DISORDER?
Pasman J; Shorter J; Jangmo A; Kurvits S; Meijsen J; Frei O; Akdeniz BC; Andreassen O; Sullivan P; Werge T; Lehto K; Tesli M; Buil A
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E77-E78
SHARED GENETIC CONTRIBUTION TO MAJOR DEPRESSIVE DISORDER AND CARDIOVASCULAR DISEASE
Bergstedt J; Pasman J; Ma Z; Parker N; Frei O; Valdimarsdottir UA; Sullivan PF; Andreassen O; Lu Y; Fang F
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E50
GENETIC EPIDEMIOLOGY AND POLYGENICITY OF PSYCHOTIC MAJOR DEPRESSIVE DISORDER
Thi TDN; Kuja-Halkola R; Kowalec K; Harder A; Xiong Y; Landen M; Hagg S; Lichtenstein P; Larsson H; Buil A; Meijsen J; Sullivan P; Dalman C; Pasman J; Lu Y

Grants

Does an early onset cause treatment-resistance in major depressive disorder by affecting educational attainment?
Swedish Research Council for Health Working Life and Welfare
1 January 2023 - 1 December 2023

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