Joar Guterstam
- Department of Clinical Neuroscience
- Centre for Psychiatry Research at CNS
- Treatment of substance use disorders – Johan Franck's Research Group
About me
MD, PhD, Docent. Specialist in psychiatry and addiction medicine.
President of the Swedish Society for Addiction Medicine (https://svenskberoendemedicin.se).
Secretary General of the European Federation of Addiction Societies (https://www.eufas.net).
Research
My PhD-thesis (2017) investigated the role of the brain opioid system in amphetamine addiction, using the imaging techniques PET and fMRI. Currently, my research is focused on pharmacotherapy for substance use disorders, and biomarkers in addiction medicine.
Teaching
I lecture regularly on topics related to psychiatry, addiction medicine and psychopharmacology. I am responsible for several courses for residents in addiction medicine, and the course in biological psychiatry for PhD students in the research school for clinical psychiatry.
I have also contributed to several textbooks and other educational materials.
Articles
- Journal article: LANCET REGIONAL HEALTH-EUROPE. 2025;54:101310Soderpalm B; Lido H; Franck J; Hakansson A; Lindqvist D; Heilig M; Guterstam J; Samuelson M; Askerup B; Wallmark-Nilsson C; de Bejczya A
- Article: PHARMACOLOGICAL REPORTS. 2025;77(3):840-849Hong M-G; Khemiri L; Guterstam J; Franck J; Jayaram-Lindstrom N; Melas PA
- Article: ALCOHOL AND ALCOHOLISM. 2024;59(6):agae070Hammarberg A; Hammarberg SI; Cuellar SR; Guterstam J
- Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2024;343:111860Kaboodvand N; Shabanpour M; Guterstam J
- Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2024;243:116075Guterstam J; Tavic C; Barosso M; Beck O
- Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2024;1240:124142Sinapour H; Guterstam J; Grosse S; Astorga-Wells J; Stambeck P; Stambeck M; Winberg J; Hermansson S; Beck O
- Article: PSYCHOLOGICAL MEDICINE. 2024;54(7):1391-1402Mansson V; Pettersson E; Mittendorfer-Rutz E; Guterstam J; Berman AH; Jayaram-Lindstroem N; Molero Y
- Article: LAKARTIDNINGEN. 2024;121:23157Guterstam J; Heilig M
- Journal article: NEUROSCIENCE APPLIED. 2024;3:104490Guterstam J; Hammarberg SI; Cuellar SR; Hammarberg A
- Journal article: EUROPEAN ADDICTION RESEARCH. 2024;30(3):138-139Guterstam J
- Article: EUROPEAN ADDICTION RESEARCH. 2024;30(1):1-13Brynte C; Konstenius M; Khemiri L; Backer A; Guterstam J; Levin FR; Jayaram-Lindstrom N; Franck J
- Article: BMC PUBLIC HEALTH. 2023;23(1):1608Metrebian N; Carter B; Eide D; Mcdonald R; Neale J; Parkin S; Dascal T; Mackie C; Day E; Guterstam J; Horsburgh K; Kaberg M; Kelleher M; Smith J; Thiesen H; Strang J
- Article: LAKARTIDNINGEN. 2022;119Guterstam J
- Article: EUROPEAN ADDICTION RESEARCH. 2022;28(3):210-219Guterstam J; Jayaram-Lindstrom N; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
- Article: BMC PSYCHIATRY. 2021;21(1):458Khemiri L; Brynte C; Konstenius M; Guterstam J; Rosendahl I; Franck J; Jayaram-Lindstrom N
- Article: LAKARTIDNINGEN. 2020;117:20165Guterstam J
- Article: PSYCHOPHARMACOLOGY. 2020;237(1):69-82Khemiri L; Steensland P; Guterstam J; de Manzano O; Franck J; Jayaram-Lindstrom N
- Article: MOLECULAR PAIN. 2020;16:1744806920927625Ponten M; Fust J; Kosek E; Guterstam J; Jensen K
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s177Guterstam J; Jayaram-Lindstrom N; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
- Article: DRUG AND ALCOHOL DEPENDENCE. 2018;191:91-97Guterstam J; Jayaram-Lindstrom N; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:s1064-s1065Guterstam J; Lindström NJ; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
- Article: TRANSLATIONAL PSYCHIATRY. 2017;7(4):e1104Jayaram-Lindstrom N; Guterstam J; Haggkvist J; Ericson M; Malmlof T; Schilstrom B; Halldin C; Cervenka S; Saijo T; Nordstrom A-L; Franck J
- Article: LAKARTIDNINGEN. 2016;113:DSU6Bloniecki Kallio V; Guterstam J; Franck J
- Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(12):2240-2251Khemiri L; Steensland P; Guterstam J; Beck O; Carlsson A; Franck J; Jayaram-Lindstrom N
- Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2015;39(11):2200-2208Walther L; de Bejczy A; Lof E; Hansson T; Andersson A; Guterstam J; Hammarberg A; Asanovska G; Franck J; Soderpalm B; Isaksson A
- Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2015;39(11):2189-2199de Bejczy A; Lof E; Walther L; Guterstam J; Hammarberg A; Asanovska G; Franck J; Isaksson A; Soderpalm B
- Journal article: LAKARTIDNINGEN. 2015;112:DEEXGuterstam J; Hammarberg A; Finn SW; Cervenka S; Lekander M; Petrovic P; Hedman E
- Article: ADDICTION. 2014;109(3):440-449Konstenius M; Jayaram-Lindstroem N; Guterstam J; Beck O; Philips B; Franck J
- Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2013;16(4):763-769Guterstam J; Jayaram-Lindstrom N; Cervenka S; Frost JJ; Farde L; Halldin C; Franck J
- Journal article: LAKARTIDNINGEN. 2013;110(3):101Guterstam J
- Journal article: EUROPEAN PSYCHIATRY. 2013;28(S1):1Konstenius M; Jayaram-Lindström N; Guterstam J; Philips B; Beck O; Franck J
- Article: BMC PSYCHIATRY. 2012;12:221Bramness JG; Gundersen OH; Guterstam J; Rognli EB; Konstenius M; Loberg E-M; Medhus S; Tanum L; Franck J
- Article: PLOS ONE. 2012;7(6):e39882Khemiri L; Guterstam J; Franck J; Jayaram-Lindstrom N
- Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2012;22:s55Guterstam J; Jayaram-Lindstrom N; Cervenka S; Halldin C; Farde L; Frost J; Franck J
- Journal article: LAKARTIDNINGEN. 2006;103(15-16):1225Guterstam J; Sjöstrand M
- Show more
All other publications
- Preprint: MEDRXIV. 2024Hong M-G; Khemiri L; Guterstam J; Franck J; Jayaram-Lindström N; Melas PA
- Review: LAKARTIDNINGEN. 2022;119:21105Johansson Capusan A; Guterstam J; Ginsberg Y; Borg Skoglund L
- Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S1054Khemiri L; Steensland P; Guterstam J; Carlsson A; Franck J; Jayaram-Lindstrom N
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S1065-S1066Guterstam J; Lindstrom NJ; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S691-S692Guterstam J; Jayaram-Lindstrom N; Berrebi J; Ingvar M; Franck J
- Corrigendum: ADDICTION. 2014;109(9):1571-1572Konstenius M; Jayaram-Lindstroem N; Guterstam J; Beck O; Philips B; Franck J
- Conference publication: EUROPEAN PSYCHIATRY. 2014;28:e109Konstenius M; Jayaram-Lindstrom N; Guterstam J; Philips B; Beck O; Franck J
- Conference publication: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2014;38:306AJayaram-Lindstrom N; Khemiri L; Carlsson A; Guterstam J; Steensland P; Franck J
- Conference publication: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2014;38:158AKhemiri L; Steensland P; Guterstam J; Carlsson A; Jayaram-Lindstrom N; Franck J
- Conference publication: BIOLOGICAL PSYCHIATRY. 2014;75(9):18SKhemiri L; Steensland P; Guterstam J; Carlsson A; Jayaram-Lindstrom N; Franck J
- Conference publication: BIOLOGICAL PSYCHIATRY. 2014;75(9):379SJayaram-Lindstrom N; Haggkvist J; Guterstam J; Malmlof T; Halldin C; Schilstrom B; Nordstrom A-L; Franck J
- Conference publication: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2012;36:64ASoderpalm B; deBejczy A; Ericson M; Guterstam J; Hammarberg A; Franck J; Asanovska G; Lof E
- Conference publication: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2012;36:358ALof E; deBejczy A; Guterstam J; Hammarberg A; Franck J; Asanovska G; Soderpalm B
- Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2012;15:41Franck J; Konstenius M; Jayaram-Lindstrom N; Philips B; Guterstam J
- Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2012;22:S55Guterstam J; Jayaram-Lindstrom N; Cervenka S; Halldin C; Farde L; Frost J; Franck J
Grants
- Swedish Research Council1 January 2024 - 31 December 2027Internet-delivered cognitive behavior therapy (CBT) for social anxiety disorder is an evidence-based treatment in regular health care. Still, a considerable proportion of treated patients do not respond. There is also a debate on the importance of patients expectations’ for therapeutic outcomes. However, experimental evidence is lacking to answer this question. Our aim is thus to investigate the placebo response in social anxiety disorder, and the link between initial placebo responsiveness and subsequent outcome of CBT. First, we will manipulate expectations of anxiety relief. A benzodiazepine (a common anti-anxiety drug) will be administered with correct or incorrect information about clinical efficacy during a public speaking task. Self-reports and moment-to-moment variability in neural response will be measured with functional magnetic resonance imaging (fMRI) during the manipulation of expectations. The balanced placebo design allows us to dissect the total treatment effect into its components: drug, placebo, and interactions between the two. Second, patients undergo internet-delivered CBT after completing the placebo experiments. This project aims to unravel expectations´ influence on treatment response, and has a two-fold significance, 1) the scientific understanding of the neural mechanisms of treatment expectations, central for placebo, and 2) the development of pre-treatment predictors of CBT outcome which could improve precision in clinical decision making.
- Swedish Research Council for Health Working Life and Welfare1 January 2021 - 31 December 2023
- Swedish Research Council1 January 2013 - 31 December 2015
- Swedish Research Council1 January 2010 - 31 December 2012
Employments
- Affiliated to Research, Department of Clinical Neuroscience, Karolinska Institutet, 2024-2026
Degrees and Education
- Docent, Psychiatry, Karolinska Institutet, 2024
- Degree Of Doctor Of Philosophy, Karolinska Institutet, 2017
- University Medical Degree, Karolinska Institutet, 2006
Visiting research fellowships
- Post-doctoral research, Zentralinstitut für Seelische Gesundheit, 2019-2020