Jiri Bartek
Professor
E-mail: jiri.bartek.1@ki.se
Telephone: +46852481267
Visiting address: Tomtebodavägen 23A, 17165 Solna
Postal address: C2 Medicinsk biokemi och biofysik, C2 Genome biology Bartek, 171 77 Stockholm
Research
- Our research focuses on various mechanistic aspects of the DDR and DNA repair pathways. Of particular interest is discovery of targets and markers for personalized cancer treatment and finding novel components or mechanisms of genome integrity maintenance. Another of our long-term goals is to further unravel the principles of ribosome biogenesis surveillance and to understand the dynamics and the finer details of the p53 pathway in sensing ribosome dysfunction, and how ribosomal stress crosstalk with the DNA damage response.
Articles
-
Journal article: NATURE COMMUNICATIONS. 2024;15(1):7748
-
Article: EUROPEAN JOURNAL OF CELL BIOLOGY. 2024;103(2):151394
-
Article: NUCLEIC ACIDS RESEARCH. 2024;52(8):4151-4166
-
Article: SCIENCE BULLETIN. 2024;69(6):803-822
-
Article: MOLECULAR AND CELLULAR ONCOLOGY. 2023;10(1):2014734
-
Article: NATURE CELL BIOLOGY. 2023;25(12):1774-1786
-
Article: CELL REPORTS. 2023;42(11):113381
-
Article: MOLECULAR CELL. 2023;83(19):3558-3573.e7
-
Article: JOURNAL OF CONTROLLED RELEASE. 2023;361:115-129
-
Article: BIOMEDICINE & PHARMACOTHERAPY. 2023;163:114801
-
Article: CELL DEATH AND DIFFERENTIATION. 2023;30(7):1666-1678
-
Article: NEURO-ONCOLOGY. 2023;25(6):1058-1072
-
Article: JAMA NETWORK OPEN. 2023;6(3):e234149
-
Article: CELL REPORTS. 2023;42(1):111979
-
Article: FRONTIERS IN ONCOLOGY. 2023;13:1218297
-
Article: NUCLEIC ACIDS RESEARCH. 2022;50(17):9948-9965
-
Article: NATURE COMMUNICATIONS. 2022;13(1):5303
-
Article: AGING-US. 2022;14(16):6381-6414
-
Article: CELL DEATH AND DIFFERENTIATION. 2022;29(8):1639-1653
-
Article: DNA REPAIR. 2022;114:103319
-
Article: SCIENCE. 2022;376(6592):476-483
-
Article: CELL REPORTS. 2022;39(1):110602
-
Article: MOLECULAR ONCOLOGY. 2022;16(7):1541-1554
-
Article: CELL DEATH & DISEASE. 2022;13(3):203
-
Article: CELL DEATH AND DIFFERENTIATION. 2022;29(3):687-696
-
Article: GEROSCIENCE. 2022;44(1):463-483
-
Article: REDOX BIOLOGY. 2022;49:102212
-
Article: NATURE CELL BIOLOGY. 2022;24(1):62-73
-
Article: AGING-US. 2021;13(23):25004-25024
-
Article: MOLECULAR CELL. 2021;81(23):4907-4923.e8
-
Article: CELL DEATH AND DIFFERENTIATION. 2021;28(12):3344-3356
-
Article: MOLECULAR CELL. 2021;81(22):4692-4708.e9
-
Article: CANCER DISCOVERY. 2021;11(10):2456-2473
-
Article: ONCOGENE. 2021;40(32):5066-5080
-
Article: SCIENCE ADVANCES. 2021;7(32):eabf7561
-
Article: NATURE COMMUNICATIONS. 2021;12(1):3937
-
Article: PLOS BIOLOGY. 2021;19(5):e3001263
-
Article: NATURE. 2021;592(7856):799-803
-
Article: NATURE COMMUNICATIONS. 2021;12(1):713
-
Article: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2021;36(1):410-424
-
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2021;16:3407-3427
-
Article: MOLECULAR ONCOLOGY. 2020;14(10):2403-2419
-
Article: NATURE COMMUNICATIONS. 2020;11(1):4828
-
Article: NATURE COMMUNICATIONS. 2020;11(1):4709
-
Article: CLINICAL CANCER RESEARCH. 2020;26(15):4031-4039
-
Article: GENES & DEVELOPMENT. 2020;34(15-16):1065-1074
-
Article: ONCOGENE. 2020;39(17):3443-3457
-
Article: MOLECULAR CELL. 2020;77(5):970-984.e7
-
Article: CELL DEATH AND DIFFERENTIATION. 2020;27(3):1134-1153
-
Article: CELL DEATH AND DIFFERENTIATION. 2020;27(2):773-789
-
Article: NUCLEIC ACIDS RESEARCH. 2019;47(22):11709-11728
-
Article: CELL REPORTS. 2019;29(11):3367-3373.e4
-
Article: SCIENTIFIC REPORTS. 2019;9(1):18622
-
Article: JOURNAL OF BIOPHOTONICS. 2019;12(12):e201900024
-
Article: NATURE MEDICINE. 2019;25(10):1540-1548
-
Article: ONCOGENE. 2019;38(40):6711-6722
-
Article: JOURNAL OF CONTROLLED RELEASE. 2019;309:158-172
-
Article: AGING-US. 2019;11(17):7206-7235
-
Article: NUCLEIC ACIDS RESEARCH. 2019;47(15):8019-8035
-
Article: CANCER RESEARCH. 2019;79(14):3762-3775
-
Article: ONCOGENE. 2019;38(28):5627-5642
-
Article: MOLECULAR ONCOLOGY. 2019;13(7):1467-1489
-
Article: REDOX BIOLOGY. 2019;24:101227
-
Article: DNA REPAIR. 2019;78:114-127
-
Article: PROSTATE. 2019;79(4):352-362
-
Article: CELL CYCLE. 2018;17(24):2697-2715
-
Article: CANCER RESEARCH. 2018;78(20):5901-5916
-
Article: NUCLEIC ACIDS RESEARCH. 2018;46(18):9484-9495
-
Article: CELL CYCLE. 2018;17(17):2146-2163
-
Article: MOLECULAR CELL. 2018;71(1):117-128.e3
-
Article: NATURE. 2018;559(7713):279-284
-
Article: CANCER CELL. 2018;33(6):1078-1093.e12
-
Article: AGING-US. 2018;10(3):434-462
-
Article: GENOME BIOLOGY. 2018;19(1):37
-
Article: BIOMATERIALS. 2018;154:275-290
-
Article: FRONTIERS IN ONCOLOGY. 2018;8:459
-
Article: NATURE. 2017;552(7684):194-199
-
Article: ONCOTARGET. 2017;8(57):96536-96552
-
Article: MOLECULAR ONCOLOGY. 2017;11(8):945-964
-
Article: ONCOGENE. 2017;36(17):2405-2422
-
Article: ANNUAL REVIEW OF CANCER BIOLOGY. 2017;1:41-57
-
Article: AGING CELL. 2017;16(1):192-197
-
Article: INTERNATIONAL JOURNAL OF CANCER. 2016;139(12):2760-2770
-
Article: JOURNAL OF PROTEOME RESEARCH. 2016;15(12):4505-4517
-
Article: BIOCONJUGATE CHEMISTRY. 2016;27(10):2558-2574
-
Article: CANCER BIOLOGY & THERAPY. 2016;17(10):1079-1088
-
Article: ONCOIMMUNOLOGY. 2016;5(10):e1183860
-
Article: GENOME BIOLOGY. 2016;17(1):185
-
Article: ONCOTARGET. 2016;7(34):54952-54964
-
Article: JOURNAL OF CELL BIOLOGY. 2016;214(4):401-415
-
Article: NATURE COMMUNICATIONS. 2016;7:12364
-
Article: NATURE CELL BIOLOGY. 2016;18(7):777-789
-
Article: MOLECULAR ONCOLOGY. 2016;10(6):879-894
-
Article: ONCOGENE. 2016;35(10):1236-1249
-
Article: CELL CYCLE. 2016;15(3):345-356
-
Article: JOURNAL OF CELL BIOLOGY. 2016;212(3):281-288
-
Article: CELL DEATH AND DIFFERENTIATION. 2016;23(2):261-269
-
Article: SCIENTIFIC REPORTS. 2016;6:19567
-
Article: NATURE COMMUNICATIONS. 2015;6:10075
-
Article: ONCOGENE. 2015;34(46):5699-5708
-
Article: NATURE PROTOCOLS. 2015;10(8):1248-1263
-
Article: CELL. 2015;162(1):146-159
-
Article: CELL DEATH AND DIFFERENTIATION. 2015;22(6):898-911
-
Article: MOLECULAR ONCOLOGY. 2015;9(6):1207-1217
-
Article: NATURE. 2015;521(7553):541-544
-
Article: ONCOTARGET. 2015;6(13):10746-10758
-
Article: CELL REPORTS. 2015;10(10):1749-1757
-
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1847(3):328-342
-
Article: MOLECULAR ONCOLOGY. 2015;9(3):601-616
-
Article: CELL CYCLE. 2015;14(3):375-387
-
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2015;58(1):41-71
-
Article: CELLULAR SIGNALLING. 2014;26(12):2903-2911
-
Article: NATURE COMMUNICATIONS. 2014;5:5348
-
Article: GENES & DEVELOPMENT. 2014;28(18):1977-1982
-
Article: CELL. 2014;158(3):633-646
-
Article: CELL DEATH & DISEASE. 2014;5(7):e1351
-
Article: CELL CYCLE. 2014;13(12):1859-1866
-
Article: BIOLOGY OF REPRODUCTION. 2014;90(6):124-9
-
Article: CELL CYCLE. 2014;13(8):1227-1236
-
Article: CELL DEATH AND DIFFERENTIATION. 2014;21(2):258-269
-
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2013;20(12):1425-1433
-
Article: CELL. 2013;155(5):1088-1103
-
Article: GENES & DEVELOPMENT. 2013;27(22):2459-2472
-
Article: ANNALS OF ONCOLOGY. 2013;24(11):2780-2785
-
Article: CELL DEATH AND DIFFERENTIATION. 2013;20(11):1485-1497
-
Article: MOLECULAR CELL. 2013;52(2):206-220
-
Article: MOLECULAR CELL. 2013;51(4):469-479
-
Article: NATURE CELL BIOLOGY. 2013;15(8):967-977
-
Article: ONCOGENE. 2013;32(31):3577-3586
-
Article: JOURNAL OF CELL BIOLOGY. 2013;201(4):511-521
-
Article: CELLULAR SIGNALLING. 2013;25(5):1186-1193
-
Article: ONCOTARGET. 2013;4(4):584-599
-
Article: NATURE. 2013;494(7438):492-496
-
Article: CELL CYCLE. 2013;12(2):251-262
-
Article: DISEASE MARKERS. 2013;35(6):895-905
-
Article: CELL CYCLE. 2012;11(20):3837-3850
-
Article: HUMAN PATHOLOGY. 2012;43(9):1363-1375
-
Article: CELL. 2012;150(4):697-709
-
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(32):26702-26714
-
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2012;19(8):803-810
-
Article: EMBO REPORTS. 2012;13(6):561-568
-
Article: CANCER CELL. 2012;21(4):517-531
-
Article: BREAST CANCER RESEARCH AND TREATMENT. 2012;132(3):955-968
-
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2012;209(3):507-520
-
Article: PLOS ONE. 2012;7(9):e44156
-
Article: NATURE CELL BIOLOGY. 2011;13(3):243-253
-
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2010;14(1-2):357-367
-
Article: GENES & DEVELOPMENT. 2009;23(16):1895-1909
-
Article: MOLECULAR ONCOLOGY. 2008;2(4):296-316
-
Article: NATURE GENETICS. 2008;40(7):844-853
-
Article: ONCOGENE. 2008;27(17):2501-2506
-
Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;373(1):38-47
-
Article: NATURE. 2006;444(7119):633-637
-
Article: INTERNATIONAL JOURNAL OF CANCER. 2006;118(11):2911-2916
-
Article: MOLECULAR AND CELLULAR BIOLOGY. 2005;25(9):3553-3562
-
Article: INTERNATIONAL JOURNAL OF CANCER. 2005;113(4):575-580
-
Article: NATURE CELL BIOLOGY. 2005;7(2):195-201
-
Article: INTERNATIONAL JOURNAL OF CANCER. 2004;111(4):543-547
-
Article: EMBO JOURNAL. 2003;22(7):1676-1687
-
Article: CANCER CELL. 2003;3(3):247-258
-
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2002;71(2):432-438
-
Article: ONCOGENE. 2001;20(39):5503-5510
-
Article: GASTROENTEROLOGY. 2001;120(7):1680-1688
-
Article: EMBO JOURNAL. 2001;20(3):422-432
-
Article: FEBS LETTERS. 2000;470(2):161-166
-
Article: HYBRIDOMA. 2000;19(1):63-72
-
Article: MOLECULAR CANCER RESEARCH. 1996;7(12):1723-1732
- Show more
All other publications
-
Letter: LEUKEMIA. 2024;38(3):663-666
-
Review: CELL DEATH AND DIFFERENTIATION. 2023;30(5):1097-1154
-
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(3):2885
-
Review: CELL DEATH AND DIFFERENTIATION. 2022;29(5):972-982
-
Corrigendum: GENOME BIOLOGY. 2022;23(1):107
-
Review: CANCERS. 2022;14(9):2126
-
Corrigendum: ONCOGENE. 2021;40(32):5153
-
Review: AUTOPHAGY. 2021;17(1):1-382
-
Review: TRENDS IN CANCER. 2021;7(1):57-76
-
Editorial comment: NATURE CANCER. 2020;1(8):758-760
-
Corrigendum: NATURE MEDICINE. 2020;26(7):1148
-
Review: CANCERS. 2020;12(4):E903-903
-
Review: PHARMACOLOGY & THERAPEUTICS. 2019;203:107395
-
Review: DNA REPAIR. 2019;81:102654
-
Review: CELLS. 2019;8(8):E869-869
-
Review: SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2019;90:94-103
-
Letter: BRITISH JOURNAL OF HAEMATOLOGY. 2019;184(2):305-308
-
Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):5396
-
Corrigendum: NUCLEIC ACIDS RESEARCH. 2018;46(18):9891
-
Review: ONCOGENE. 2018;37(18):2351-2366
-
Review: ANNALS OF ONCOLOGY. 2018;29(3):563-572
-
Editorial comment: CELL CYCLE. 2018;17(2):145-146
-
Published conference paper: MOLECULAR THERAPY. 2017;25(7):1476-1490
-
Editorial comment: ONCOIMMUNOLOGY. 2016;5(2):e1080416
-
Corrigendum: CELL. 2015;162(5):1169
-
Editorial comment: CELL DEATH AND DIFFERENTIATION. 2015;22(6):888-889
-
Letter: CANCER RESEARCH. 2015;75(4):777-778
-
Editorial comment: EXPERIMENTAL CELL RESEARCH. 2014;329(1):1
-
Review: NATURE. 2013;501(7467):338-345
-
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2012;13(10):13322-13337
-
Review: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2012;83(7):753-760
-
Review: MOLECULAR THERAPY. 2012;20(5):887-897
- Show more
Employments
- Professor, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2015-
Degrees and Education
- PhD, Inst. Molec. Genetics, Czech Academy of Sciences, 1983
- MD, Medical Faculty, Palacký University, Olomouc, 1979
Distinction and awards
- Fernströmstiftelsens Stora nordiska pris, 2016
- Silver Medal of Merits from the Senate of the Czech Republic, 2013
- Elected member of the Danish Royal Academy of Sciences and Arts, 2012
- Shai-Shacknai Prize for Cancer Research, University of Jerusalem, Israel, 2009
- Founding member: European Academy of Cancer Sciences, 2009
- Doctor Honoris Causa, Palacky University, Olomouc, Czech Republic, 2005
- G. J. Mendel Honorary Medal for Merit in the Biological Sciences, 2003
- Novo Nordisk Prize, Denmark, Novo Nordisk (Denmark), 2003
- Alfred Benzons Prize, Denmark, Alfred Benzon Foundation, 2002
- Honorary Professor, The Faculty of Health Sciences, , Aarhus University, 2002
- Honorary Professor, The Faculty of Health Sciences, University of Copenhagen, 2002
- Elected member of the European Molecular Biology Organization – EMBO, European Molecular Biology Organization, 2000
- The Prize of the Danish Association for Cancer Research, 1998
- J.E. Purkyne Prize for medical sciences, Czech Medical Association of J.E. Purkyne, 1988