Denna sida på svenska
Loading profile information...

Research description

Genetic etiology of bipolar disorder  

Familial risks for bipolar disorder and subtypes, the individual and familial co-occurrence of other psychiatric disorders for bipolar disorder, and their genetic correlations. The data are genetically informative and based on Swedish national registers. 

Effectiveness of lithium treatment for related outcomes

Potential associations and possible difference between use of lithium and valproate and risk of concomitant suicide-related events.

Effectiveness of medication in preventing psychiatric hospitalization.  

Response to lithium treatment for bipolar disorder

Genome-wide association studies on response to lithium treatment for bipolar disorder and on lithium-responsive bipolar disorder.

The proportion of variance for lithium-responsive bipolar disorder explained by common variants. 



Pharmacological treatment and risk of psychiatric hospital admission in bipolar disorder
Joas E, Karanti A, Song J, Goodwin Gm, Lichtenstein P, Landén M
The British journal of psychiatry : the journal of mental science 2017;210(3):197-202

Similar familial risk in multiple sclerosis subgroups
Song J, Karrenbauer V, Manouchehrinia A, Almqvist C, Hillert J, Westerlind H
Multiple sclerosis (Houndmills, Basingstoke, England) 2017;23(13):1782-1785

A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia
Hughes T, Hansson L, Sønderby Ie, Athanasiu L, Zuber V, Tesli M, et al
Biological psychiatry 2016;80(4):323-330

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder
Song J, Bergen Se, Di Florio A, Karlsson R, Charney A, Ruderfer Dm, et al
Molecular psychiatry 2016;21(9):1290-7

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder
Hou L, Bergen Se, Akula N, Song J, Hultman Cm, Landén M, et al
Human molecular genetics 2016;25(15):3383-3394

Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population
Song J, Bergen Se, Kuja-halkola R, Larsson H, Landén M, Lichtenstein P
Bipolar disorders 2015;17(2):184-93