Jesper Säfholm

Jesper Säfholm

Research Specialist
Visiting address: Nobels väg 13, 17177 Stockholm
Postal address: C6 Institutet för miljömedicin, C6 Integrativ metabolomik Wheelock, 171 77 Stockholm

About me

  • I am currently employed as Assistant Professor in the research environment of
    the Unit of Integrative Metabolomics. I initiated my PhD-studies within 

  • the field of airway pharmacology and physiology in 2008 and graduated 2013.
    This was followed by post graduate work 2014-2018 on mechanisms in asthmatic
    airway inflammation and I subsequently acquired an assistant professorship
    for continuation of translational airway pharmacology studies of lipid
    mediators, airway hyperresponsiveness and inflammation using /in vivo, ex
    vivo/ and /in vitro/ methods in both animal and human tissue.
    I am currently a supervisor of three PhD-students in the lab and have successfully supervised Master students during
    their graduation projects.
    Between 1999 and 2012 I worked at Astra Zeneca within the departements Safety
    Assessment, Neuroscience and Molecular Toxicology as a research technician.
    * In 2020 I was given the IMM Junior Faculty Strategic Award by The
    Institute of Environmental Medicine, IMM, Karolinska Institutet.
    * In 2017 I was awarded the Veritas Pharma Inc. Dom Spina Prize by the
    British Pharmacological Society.
    *Commissions of trust*
    * 2018-2019 I was the organiser of a bi-monthly seminar series within
    physiology and pharmacology at Karolinska Instiutet.
    * 2014-2017 I was board member of Centre for Allergy Research PhD and
    Postdoc Association at Karolinska Instiutet.
    * 2009-2013 I was member of the Educational Board at the Institute of
    Environmental Medicine at Karolinska Instiutet.
    * High School Education (Chemistry), Europaskolan, Strängnäs, 1998-2001
    * Master of Science in Biology (MSc), Uppsala Universitet, Uppsala,
    * Doctor of Philosophy (PhD), Institute of Environmental Medicine and
    Experimental Asthma and Allergy Research, Karolinska Institutet, Stockholm


  • Asthma is a major public health concern affecting between 5 and 10% of the
    population. The exacerbations of asthma occur on a background of chronic
    inflammation where inflammatory cells, such as eosinophils and mast cells,
    and their respective mediators, including lipid mediators, orchestrate
    different patterns of inflammation and bronchoconstriction. The purpose of my
    research programme is to define the role of different lipid mediators for
    airway function in relation to the pathobiology of asthma.


  • I teach the sections ‘Anatomy and physiology of the pulmonary system’ and
    ‘Animal models in pulmonary diseases’ in the International Master's
    Programme in Toxicology at the Institute of Environmental medicine,
    Karolinska Institutet.


All other publications


  • Research Specialist, Institute of Environmental Medicine, Karolinska Institutet, 2022-

Degrees and Education

  • Degree Of Doctor Of Philosophy, Institute of Environmental Medicine, Karolinska Institutet, 2013

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