Jenny Flygare

Publications
CV
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Articles

Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2015;3(5):e00171
FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity.
Ahmed D; de Verdier PJ; Ryk C; Lunqe O; Stål P; Flygare J
Article: PEERJ. 2015;3:e1056
Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling
Almestrand S; Wang X; Jeppsson-Ahlberg A; Nordgren M; Flygare J; Christensson B; Rossner S; Sander B
Article: ONCOSCIENCE. 2014;1(8):550-557
Perturbations of the endocannabinoid system in mantle cell lymphoma: correlations to clinical and pathological features.
Wasik AM; Nygren L; Almestrand S; Zong F; Flygare J; Wennerholm SB; Saft L; Andersson P; Kimby E; Wahlin BE; Christensson B; Sander B
Article: CANCER LETTERS. 2014;348(1-2):119-125
Secondary stimulation from Bacillus Calmette-Guerin induced macrophages induce nitric oxide independent cell-death in bladder cancer cells
Thiel T; Ryk C; Chatzakos V; Grufman KH; Bavand-Chobot N; Flygare J; Wiklund NP; de Verdier PJ
Article: BIOCHEMICAL PHARMACOLOGY. 2012;84(5):712-721
Inhibition of sphingosine kinase 1 enhances cytotoxicity, ceramide levels and ROS formation in liver cancer cells treated with selenite
Chatzakos V; Rundlof AK; Ahmed D; de Verdier PJ; Flygare J
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2012;16(7):1593-1605
Effects of redox modulation by inhibition of thioredoxin reductase on radiosensitivity and gene expression
Selenius M; Hedman M; Brodin D; Gandin V; Rigobello MP; Flygare J; Marzano C; Bindoli A; Brodin O; Bjornstedt M; Fernandes AP
Article: PROTEOME SCIENCE. 2009;7:43
A comparison between protein profiles of B cell subpopulations and mantle cell lymphoma cells
Stranneheim H; Orre LM; Lehtio J; Flygare J
Article: MOLECULAR CANCER RESEARCH. 2009;7(7):1086-1098
Potentiation of Cannabinoid-Induced Cytotoxicity in Mantle Cell Lymphoma through Modulation of Ceramide Metabolism
Gustafsson K; Sander B; Bielawski J; Hannun YA; Flygare J
Article: BMC IMMUNOLOGY. 2009;10:2
High expression of 5-lipoxygenase in normal and malignant mantle zone B lymphocytes
Mahshid Y; Lisy M-R; Wang X; Spanbroek R; Flygare J; Christensson B; Bjorkholm M; Sander B; Habenicht AJR; Claesson H-E
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;143(2):248-252
The subcellular Sox11 distribution pattern identifies subsets of mantle cell lymphoma: correlation to overall survival
Wang X; Asplund AC; Porwit A; Flygare J; Smith CIE; Christensson B; Sander B
Article: INTERNATIONAL JOURNAL OF CANCER. 2008;123(5):1025-1033
Expression of cannabinoid receptors type 1 and type 2 in non-Hodgkin lymphoma: Growth inhibition by receptor activation
Gustafsson K; Wang X; Severa D; Eriksson M; Kimby E; Merup M; Christensson B; Flygare J; Sander B
Article: MOLECULAR PHARMACOLOGY. 2006;70(5):1612-1620
Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma
Gustafsson K; Christensson B; Sander B; Flygare J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;341(2):334-342
Rad51-related changes in global gene expression
Orre LM; Fält S; Szeles A; Lewensohn R; Wennborg A; Flygare J
Article: FEBS LETTERS. 2005;579(30):6885-6889
Cannabinoid receptor ligands mediate growth inhibition and cell death in mantle cell lymphoma
Flygare J; Gustafsson K; Kimby E; Christensson B; Sander B
Article: INTERNATIONAL JOURNAL OF CANCER. 2005;117(3):418-430
Mantle cell lymphomas with low levels of cyclin D1 long mRNA transcripts are highly proliferative and can be discriminated by elevated cyclin A2 and cyclin B1
Sander B; Flygare J; Porwit-MacDonald A; Smith CIE; Emanuelsson E; Kimby E; Liden J; Christensson B
Article: EXPERIMENTAL CELL RESEARCH. 2001;268(1):61-69
Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis
Flygare J; Fält S; Ottervald J; Castro J; Dackland Å; Hellgren D; Wennborg A
Article: THE FEBS JOURNAL. 2000;267(19):5977-5982
Caspase-3 mediated cleavage of HsRad51 at an unconventional site
Flygare J; Hellgren D; Wennborg A
Article: GENE. 2000;246(1-2):247-254
p53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom's syndrome GM1492 fibroblasts
Magnusson KP; Sandström M; Ståhlberg M; Larsson M; Flygare J; Hellgren D; Wiman KG; Ljungquist S
Article: INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. 1999;43(1):191-198
Dna double-strand break repair, DNA-PK, and DNA ligases in two human squamous carcinoma cell lines with different radiosensitivity
Polischouk AG; Cedervall B; Ljungquist S; Flygare J; Hellgren D; Grénman R; Lewensohn R
Article: FEBS LETTERS. 1998;427(2):247-251
Proteolytic cleavage of HsRad51 during apoptosis
Flygare J; Armstrong RC; Wennborg A; Orsan S; Hellgren D
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1996;1312(3):231-236
Expression of the human RAD51 gene during the cell cycle in primary human peripheral blood lymphocytes
Flygare J; Benson F; Hellgren D
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All other publications

Review: SEMINARS IN CANCER BIOLOGY. 2008;18(3):176-189
The endocannabinoid system in cancer - Potential therapeutic target?
Flygare J; Sander B
Thesis / dissertation: 2000
Expression and regulation of Rad51 in human cells
Flygare, Jenny

Employments

Researcher, Teaching and learning, Karolinska Institutet, 2020-

Degrees and Education

Docent, Karolinska Institutet, 2010
Doctor Of Philosophy, Department of Biosciences and Nutrition, Karolinska Institutet, 2000

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