Jean Tyan
About me
I am currently a PhD student in the US National Institutes of Health-Karolinska Institutet (NIH-KI) Doctoral Program in Neuroscience. I have backgrounds in neuroscience and epidemiology and have a special interest in bridging basic, clinical, and population-level findings to alleviate health disparities in Alzheimer’s and other neurodegenerative diseases.
- 2022: M.H.S. in Epidemiology - Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Thesis: Examining relationships between discriminatory experiences, biological aging, and dementia in a diverse, longitudinal cohort, advised by Dr. Aisha Dickerson
- 2020: B.S. in Biopsychology, Cognition, and Neuroscience - University of Michigan, Ann Arbor, Michigan. Honors Thesis: Revealing the roles of sleep-preparatory behaviors in sleep physiology, advised by Dr. Ada Eban-Rothschild
- 2020: B.S. in Biology, Health, and Society - University of Michigan, Ann Arbor, Michigan
Research
My doctoral project, co-supervised by Daniel Ferreira at KI and Yihong Ye at NIH, focuses on the identification of fluid biomarkers to enhance opportunities for early and accurate diagnosis of Alzheimer’s disease, Parkinson’s disease, and dementia with Lewy bodies. We hope to leverage both basic and clinical-level interrogation methods to identify and characterize secretory proteins differentially present in these neurodegenerative diseases and assess their clinical diagnostic and prognostic utility.
Teaching
- 2022: Statistical Methods in Public Health II - Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
- 2021: Statistical Methods in Public Health I - Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health
- 2018-2020: Organic Chemistry II - Science Learning Center, University of Michigan
- 2018-2020: Organic Chemistry I - Science Learning Center, University of Michigan
Articles
- Journal article: NATURE COMMUNICATIONS. 2024;15(1):1457
- Journal article: NATURE NEUROSCIENCE. 2023;26(2):196-212
- Journal article: CURRENT BIOLOGY. 2022;32(4):806-822.e7
- Journal article: CURRENT OPINION IN PHYSIOLOGY. 2020;15:159-166
- Journal article: SLEEP. 2020;43(Supplement_1):A82