Jasmin Hassan
Affiliated to Research
E-mail: jasmin.hassan@ki.se
Visiting address: Hälsovägen, Enheten för obstetrik och gynekologi C1:77, 14186 Stockholm
Postal address: H9 Klinisk vetenskap, intervention och teknik, H9 CLT Obstetrik o gynekologi Damdimopoulou, 141 52 Huddinge
Research
- Adult women who risk losing fertility due to gonadotoxic treatments are
offered fertility preservation in the form of cryopreservation of oocytes,
embryos or ovarian tissue. All of these routines are established clinical
routines. If the patient has recovered and has wishes for pregnancy,
cryopreserved oocytes and embryos can be used for in vitro fertilisation,
cryopreserved ovarian tissue can be transplanted back. Unfortunately, there
is no such established routine for pre-pubertal girls, making them the only
patient group in Sweden that has no systematic opportunity for fertility
preservation.
Due to the immaturity of the oocytes in pre-pubertal girls, fertility
preservation through cryopreservation of oocytes or embryos is not possible.
This leaves only ovarian tissue cryopreservation as an option. However, it is
currently not clear if ovarian tissue from young patients is functionally
similar to adult ovarian tissue. Earlier studies have shown that ovarian
tissue from young patients contain more follicles with abnormal morphology
and have worse grow potential /in vitro/ compared to follicles from adults
(Anderson /et al/./ /2014 Hum Rep). With SveaFertil we will implement the
first national fertility preservation project for girls and young women in
Sweden and to develop fertility preservation options for young patients
through molecular characterisation of child ovarian tissue. SveaFertil will
generate an unprecedented collection of detailed data on human ovarian
biology from childhood to adulthood, which will help us tremendously in
developing appropriate fertility preservation options for young patients.
Articles
- Article: REPRODUCTIVE BIOMEDICINE ONLINE. 2023;47(4):103287
- Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:903505
- Article: ENVIRONMENT INTERNATIONAL. 2021;155:106589
All other publications
- Thesis / dissertation: 2024
- Review: HORMONE RESEARCH IN PAEDIATRICS. 2020;93(11-12):599-608