Jari Tiihonen

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About me

Jari Tiihonen is Professor of Clinical Psychiatry at Karolinska Institutet since 2011. He conducts registry studies in the field of psychopharmacology, for example on suicide risk in people who use antidepressant or antipsychotic drugs.

Articles

Article: WORLD PSYCHIATRY. 2025;24(2):250-259
Effectiveness of clozapine augmentation with specific doses of other antipsychotics in schizophrenia: a meta-analysis from two nationwide cohorts
Tiihonen J; Tanskanen A; Mittendorfer-Rutz E; Howes OD; Correll CU; Siskind D; Taipale H
Article: NORDIC JOURNAL OF PSYCHIATRY. 2025;79(4):314-320
Sweden vs. Finland - forensic psychiatric care and subsequent recidivism in violent crime
Sivak L; Ojansuu I; Tiihonen J; Laehteenvuo M; Forsman J
Article: BRITISH JOURNAL OF PSYCHIATRY. 2025;:1-7
Real-world effectiveness of antipsychotic medication in relapse prevention after cannabis-induced psychosis
Mustonen A; Taipale H; Denissoff A; Ellila V; Di Forti M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J; Niemelae S
Article: PSYCHOLOGICAL MEDICINE. 2025;55:e117
Sleep and schizophrenia polygenic scores in non-affective and affective psychotic disorders
Cederlof E; Holm M; Kampe A; Ahola-Olli A; Kantojarvi K; Lahteenvuo M; Ahti J; Hietala J; Hakkinen K; Isometsa E; Tuulio-Henriksson A; Kampman O; Lahdensuo K; Lonnqvist J; Tiihonen J; Turunen H; Wegelius A; Veijola J; Kieseppa T; Palotie A; Paunio T
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2025;32(4):e70134
Criminal Behavior in Early Onset Neurodegenerative Diseases
Soppela H; Aaltonen M; Aho K; Heikkinen S; Kivisild A; Lehtonen A; Leppanen L; Maki-Petaja-Leinonen A; Rinnankoski I; Tervonen L; Tiihonen J; Lahteenvuo M; Haapasalo A; Portaankorva AM; Hartikainen P; Katisko K; Kruger J; Solje E
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2025;182(4):389-400
Kynurenic Acid and Promotion of Activity-Dependent Synapse Elimination in Schizophrenia
Orhan F; Malwade S; Khanlarkhani N; Gkogka A; Langeder A; Jungholm O; Koskuvi M; Lehtonen S; Schwieler L; Jardemark K; Tiihonen J; Koistinaho J; Erhardt S; Engberg G; Samudyata S; Sellgren CM
Article: ACTA NEUROPSYCHIATRICA. 2025;37:e54
Influence of CYP2D6 phenotype on adherence, adverse effects, and attitudes in aripiprazole and risperidone users
Hietala E; Solismaa A; Lahteenvuo M; Ahola-Olli AV; Hakkinen K; Suokas K; Isometsa E; Suvisaari J; Kieseppa T; Holm M; Tiihonen J; Lonnqvist J; Hietala J; Wegelius A; Lahdensuo K; Haaki W; Kampman O
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2025;152(2):104-111
The Role of Antipsychotics and Mood Stabilizers in Preventing Sickness Absence Among Employed Individuals With Bipolar Disorder: A Nationwide Register-Based Study
Holm M; Tanskanen A; Tiihonen J; Taipale H
Article: LANCET PSYCHIATRY. 2025;12(3):198-207
Real-world effectiveness of pharmacological maintenance treatment of bipolar depression: a within-subject analysis in a Swedish nationwide cohort
Ermis C; Taipale H; Tanskanen A; Vieta E; Correll CU; Mittendorfer-Rutz E; Tiihonen J
Article: ECLINICALMEDICINE. 2025;81:103108
Machine learning-based mortality risk assessment in first-episode bipolar disorder: a transdiagnostic external validation study
Lieslehto J; Tiihonen J; Lahteenvuo M; Kautzky A; Akhtar A; Armannsdottir B; Leucht S; Correll CU; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2025;:sbaf011
Is it Possible To Identify Patients After Their First Hospitalization for a Psychotic Disorder Who Do Not Use Anti-Psychotics and are Not Later Rehospitalized?
Krivoy A; Tiihonen J; Nissan J; Dotan A; Arnheim D; Menkes-Caspi N; Taub S; Tuppurainen H; Mittendorfer-Rutz E; Davidson M; Davis JM; Weiser M; Taipale H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2025;182(4):0-348
Continuous Dopamine D2 Receptor Blockade and Long-Term Outcome in First-Episode Schizophrenia
Tiihonen J; Tanskanen A; Solmi M; Rubio JM; Correll CU; Kane JM; Taipale H
Article: SCHIZOPHRENIA. 2025;11(1):21
miRNA profiling of hiPSC-derived neurons from monozygotic twins discordant for schizophrenia
Rasanen N; Tiihonen J; Koskuvi M; Trontti K; Cheng L; Hill AF; Lehtonen S; Vaurio O; Ojansuu I; Lahteenvuo M; Pietilainen O; Koistinaho J
Article: ADDICTION. 2025;:1422-1430
Relapse in substance-induced psychosis and associated risk factors. A Nationwide register-linkage study from Sweden
Ellila V; Taipale H; Tiihonen J; Mittendorfer-Rutz E; Niemela S
Article: LANCET PSYCHIATRY. 2025;12(2):122-130
Comparative effectiveness of antipsychotic treatment strategies for relapse prevention in first-episode schizophrenia in Finland: a population-based cohort study.
Taipale H; Tanskanen A; Howes O; Correll CU; Kane JM; Tiihonen J
Article: EUROPEAN PSYCHIATRY. 2025;68(1):e17-13
The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force
Verdoux H; Bittner RA; Hasan A; Qubad M; Wagner E; Lepetit A; Arrojo-Romero M; Bachmann C; Beex-Oosterhuis M; Bogers J; Celofiga A; Cohen D; de Berardis D; de Hert M; de las Cuevas C; Ebdrup BH; Fountoulakis KN; Guinart D; Keating D; Kopecek M; Lally J; Lazary J; Luykx JJ; Amigo OM; Molden E; Nielsen J; O'Donoghue B; Oswald P; Radulescu FS; Rohde C; Sagud M; Sanz EJ; Filipcic IS; Sommer IE; Taipale H; Tiihonen J; Tuppurainen H; Veerman S; Wilkowska A; Spina E; Schulte P
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2025;90:1-15
Collaborative outcomes study on health and functioning during infection times (COH-FIT): Insights on modifiable and non-modifiable risk and protective factors for wellbeing and mental health during the COVID-19 pandemic from multivariable and network analyses
Solmi M; Thompson T; Cortese S; Estrade A; Agorastos A; Radua J; Dragioti E; Vancampfort D; Thygesen LC; Aschauer H; Schloegelhofer M; Aschauer E; Schneeberger A; Huber CG; Hasler G; Conus P; Do Cuenod KQ; von Kanel R; Arrondo G; Fusar-Poli P; Gorwood P; Llorca P-M; Krebs M-O; Scanferla E; Kishimoto T; Rabbani G; Skonieczna-Zydecka K; Brambilla P; Favaro A; Takamiya A; Zoccante L; Colizzi M; Bourgin J; Kaminski K; Moghadasin M; Seedat S; Matthews E; Wells J; Vassilopoulou E; Gadelha A; Su K-P; Kwon JS; Kim M; Lee TY; Papsuev O; Mankova D; Boscutti A; Gerunda C; Saccon D; Righi E; Monaco F; Croatto G; Cereda G; Demurtas J; Brondino N; Veronese N; Enrico P; Politi P; Ciappolino V; Pfennig A; Bechdolf A; Meyer-Lindenberg A; Kahl KG; Domschke K; Bauer M; Koutsouleris N; Winter S; Borgwardt S; Bitter I; Balazs J; Czobor P; Unoka Z; Mavridis D; Tsamakis K; Bozikas VP; Tunvirachaisakul C; Maes M; Rungnirundorn T; Supasitthumrong T; Haque A; Brunoni AR; Costardi CG; Schuch FB; Polanczyk G; Luiz JM; Fonseca L; Aparicio LV; Valvassori SS; Nordentoft M; Vendsborg P; Hoffmann SH; Sehli J; Sartorius N; Heuss S; Guinart D; Hamilton J; Kane J; Rubio J; Sand M; Koyanagi A; Solanes A; Andreu-Bernabeu A; Caceres ASJ; Arango C; Diaz-Caneja CM; Hidalgo-Mazzei D; Vieta E; Gonzalez-Penas J; Fortea L; Parellada M; Fullana MA; Verdolini N; Andrlikova E; Janku K; Millan MJ; Honciuc M; Moniuszko-Malinowska A; Loniewskiaf I; Samochowiec J; Kiszkiel L; Marlicz M; Sowa P; Marlicz W; Spies G; Stubbs B; Firth J; Sullivan S; Darcin AE; Aksu H; Dilbaz N; Noyan O; Kitazawa M; Kurokawa S; Tazawa Y; Anselmi A; Cracco C; Machado AIE; Estrade N; De Leo D; Curtis J; Berk M; Carvalho AF; Ward P; Teasdale S; Rosenbaum S; Marx W; Horodnic AV; Oprea L; Alexinschi O; Ifteni P; Turliuc S; Ciuhodaru T; Bolos A; Matei V; Nieman DH; Sommer I; van Os J; van Amelsvoort T; Sunat C-F; Guuat T-W; Jiao C; Zhang J; Fan J; Zou L; Yu X; Chi X; de Timary P; van Winkel R; Ng B; de Leon EP; Arellano R; Roman R; Sanchez T; Movina L; Morgado P; Brissos S; Aizberg O; Mosina A; Krinitski D; Mugisha J; Sadeghi-Bahmani D; Sheybani F; Sadeghi M; Hadi S; Brandei S; Errazuriz A; Crossley N; Ristic DI; Lopez-Jaramilli C; Efthymiou D; Kuttichira P; Kallivayalil RA; Javed A; Afridi MI; James B; Seb-Akahomen OJ; Fiedorowicza J; Daskalakis J; Yatham LN; Yang L; Okasha T; Dahdouh A; Tiihonen J; Shin JI; Lee J; Mhalla A; Gaha L; Brahim T; Altynbekov K; Negay N; Nurmagambetova S; Abu Jamei Y; Weiser M; Correll CU
Article: JOURNAL OF AFFECTIVE DISORDERS. 2025;368:136-142
Cause-specific mortality in treatment-resistant major depression: Population-based cohort study
Gustafsson TT; Taipale H; Lahteenvuo M; Tanskanen A; Svirskis T; Huoponen S; Tiihonen J
Article: JAMA PSYCHIATRY. 2025;82(1):94-98
Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder
Lahteenvuo M; Tiihonen J; Solismaa A; Tanskanen A; Mittendorfer-Rutz E; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2025;151(1):81-91
Dosing levels of antipsychotics and mood stabilizers in bipolar disorder: A Nationwide cohort study on relapse risk and treatment safety
Lintunen J; Hamina A; Lahteenvuo M; Paljarvi T; Tanskanen A; Tiihonen J; Taipale H
Article: SCHIZOPHRENIA. 2024;10(1):124
General medical comorbidities in psychotic disorders in the Finnish SUPER study
Ahti J; Kieseppae T; Haaki W; Suvisaari J; Niemelae S; Suokas K; Holm M; Wegelius A; Kampman O; Laehteenvuo M; Paunio T; Tiihonen J; Hietala J; Isometsae E
Article: PSYCHOLOGICAL MEDICINE. 2024;54(16):1-11
Labor market marginalization in individuals with bipolar disorder: a Swedish nationwide register-based sibling comparison study
Armannsdottir B; Taipale H; Akhtar A; Kautzky A; Bjorkenstam E; Lieslehto J; Tiihonen J; Amin R; Mittendorfer-Rutz E
Article: PSYCHIATRY RESEARCH. 2024;342:115972
Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study.
Solmi M; Thompson T; Estradé A; Agorastos A; Radua J; Cortese S; Dragioti E; Vancampfort D; Thygesen LC; Aschauer H; Schlögelhofer M; Aschauer E; Schneeberger A; Huber CG; Hasler G; Conus P; Cuénod KQD; von Känel R; Arrondo G; Fusar-Poli P; Gorwood P; Llorca P-M; Krebs M-O; Scanferla E; Kishimoto T; Rabbani G; Skonieczna-Żydecka K; Brambilla P; Favaro A; Takamiya A; Zoccante L; Colizzi M; Bourgin J; Kamiński K; Moghadasin M; Seedat S; Matthews E; Wells J; Vassilopoulou E; Gadelha A; Su K-P; Kwon JS; Kim M; Lee TY; Papsuev O; Manková D; Boscutti A; Gerunda C; Saccon D; Righi E; Monaco F; Croatto G; Cereda G; Demurtas J; Brondino N; Veronese N; Enrico P; Politi P; Ciappolino V; Pfennig A; Bechdolf A; Meyer-Lindenberg A; Kahl KG; Domschke K; Bauer M; Koutsouleris N; Winter S; Borgwardt S; Bitter I; Balazs J; Czobor P; Unoka Z; Mavridis D; Tsamakis K; Bozikas VP; Tunvirachaisakul C; Maes M; Rungnirundorn T; Supasitthumrong T; Haque A; Brunoni AR; Costardi CG; Schuch FB; Polanczyk G; Luiz JM; Fonseca L; Aparicio LV; Valvassori SS; Nordentoft M; Vendsborg P; Hoffmann SH; Sehli J; Sartorius N; Heuss S; Guinart D; Hamilton J; Kane J; Rubio J; Sand M; Koyanagi A; Solanes A; Andreu-Bernabeu A; Cáceres ASJ; Arango C; Díaz-Caneja CM; Hidalgo-Mazzei D; Vieta E; Gonzalez-Peñas J; Fortea L; Parellada M; Fullana MA; Verdolini N; Andrlíková E; Janků K; Millan MJ; Honciuc M; Moniuszko-Malinowska A; Łoniewski I; Samochowiec J; Kiszkiel Ł; Marlicz M; Sowa P; Marlicz W; Spies G; Stubbs B; Firth J; Sullivan S; Darcin AE; Aksu H; Dilbaz N; Noyan O; Kitazawa M; Kurokawa S; Tazawa Y; Anselmi A; Cracco C; Machado AI; Estrade N; De Leo D; Curtis J; Berk M; Carvalho AF; Ward P; Teasdale S; Rosenbaum S; Marx W; Horodnic AV; Oprea L; Alexinschi O; Ifteni P; Turliuc S; Ciuhodaru T; Bolos A; Matei V; Nieman DH; Sommer I; van Os J; van Amelsvoort T; Sun C-F; Guu T-W; Jiao C; Zhang J; Fan J; Zou L; Yu X; Chi X; de Timary P; van Winkel R; Ng B; Peña de León E; Arellano R; Roman R; Sanchez T; Movina L; Morgado P; Brissos S; Aizberg O; Mosina A; Krinitski D; Mugisha J; Sadeghi-Bahmani D; Sheybani F; Sadeghi M; Hadi S; Brand S; Errazuriz A; Crossley N; Ristic DI; López-Jaramillo C; Efthymiou D; Kuttichira P; Kallivayalil RA; Javed A; Afridi MI; James B; Seb-Akahomen OJ; Fiedorowicz J; Daskalakis J; Yatham LN; Yang L; Okasha T; Dahdouh A; Tiihonen J; Shin JI; Lee J; Mhalla A; Gaha L; Brahim T; Altynbekov K; Negay N; Nurmagambetova S; Jamei YA; Weiser M; Correll CU
Article: JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY. 2024;64(4):499-519
Collaborative Outcomes Study on Health and Functioning During Infection Times (COH-FIT): Global and Risk-Group Stratified Course of Well-Being and Mental Health During the COVID-19 Pandemic in Adolescents
Solmi M; Thompson T; Cortese S; Estrade A; Agorastos A; Radua J; Dragioti E; Vancampfort D; Thygesen LC; Aschauer H; Schloegelhofer M; Aschauer E; Schneeberger AA; Huber CG; Hasler G; Conus P; Do Cuenod KQ; von Kanel R; Arrondo G; Fusar-Poli P; Gorwood P; Llorca P-M; Krebs M-O; Scanferla E; Kishimoto T; Rabbani G; Skonieczna-Zydecka K; Brambilla P; Favaro A; Takamiya A; Zoccante L; Colizzi M; Bourgin J; Kaminski K; Moghadasin M; Seedat S; Matthews E; Wells J; Vassilopoulou E; Gadelha A; Su K-P; Kwon JS; Kim M; Lee TY; Papsuev O; Mankova D; Boscutti A; Gerunda C; Saccon D; Righi E; Monaco F; Croatto G; Cereda G; Demurtas J; Brondino N; Veronese N; Enrico P; Politi P; Ciappolino V; Pfennig A; Bechdolf A; Meyer-Lindenberg A; Kahl KG; Domschke K; Bauer M; Koutsouleris N; Winter S; Borgwardt S; Bitter I; Balazs J; Czobor P; Unoka Z; Mavridis D; Tsamakis K; Bozikas VP; Tunvirachaisakul C; Maes M; Rungnirundorn T; Supasitthumrong T; Haque A; Brunoni AR; Costardi CG; Schuch FB; Polanczyk G; Luiz JM; Fonseca L; Aparicio LV; Valvassori SS; Nordentoft M; Vendsborg P; Hoffmann SH; Sehli J; Sartorius N; Heuss S; Guinart D; Hamilton J; Kane J; Rubio J; Sand M; Koyanagi A; Solanes A; Andreu-Bernabeu A; Caceres ASJ; Arango C; Diaz-Caneja CM; Hidalgo-Mazzei D; Vieta E; Gonzalez-Penas J; Fortea L; Parellada M; Fullana MA; Verdolini N; Andrlikova E; Janku K; Millan MJ; Honciuc M; Moniuszko-Malinowska A; Loniewski I; Samochowiec J; Kiszkiel L; Marlicz M; Sowa P; Marlicz W; Spies G; Stubbs B; Firth J; Sullivan S; Darcin AE; Aksu H; Dilbaz N; Noyan O; Kitazawa M; Kurokawa S; Tazawa Y; Anselmi A; Cracco C; Machado AI; Estrade N; De Leo D; Curtis J; Berk M; Carvalho AF; Ward P; Teasdale S; Rosenbaum S; Marx W; Horodnic AV; Oprea L; Alexinschi O; Ifteni P; Turliuc S; Ciuhodaru T; Bolos A; Matei V; Nieman DH; Sommer I; van Os J; van Amelsvoort T; Sun C-F; Guu T-W; Jiao C; Zhang J; Fan J; Zou L; Yu X; Chi X; de Timary P; van Winkel R; Ng B; Pena E; Arellano R; Roman R; Sanchez T; Movina L; Morgado P; Brissos S; Aizberg O; Mosina A; Krinitski D; Mugisha J; Sadeghi-Bahmani D; Sheybani F; Sadeghi M; Hadi S; Brand S; Errazuriz A; Crossley N; Ristic DI; Lopez-Jaramillo C; Efthymiou D; Kuttichira P; Kallivayalil RA; Javed A; Afridi MI; James B; Seb-Akahomen OJ; Fiedorowicz J; Daskalakis J; Yatham LN; Yang L; Okasha T; Dahdouh A; Tiihonen J; Shin JI; Lee J; Mhalla A; Gaha L; Brahim T; Altynbekov K; Negay N; Nurmagambetova S; Abu Jamei Y; Weiser M; Correll CU
Article: SCHIZOPHRENIA BULLETIN. 2024;50(6):1287-1294
Antipsychotic Use and Psychiatric Hospitalization in First-Episode Non-affective Psychosis and Cannabis Use Disorder: A Swedish Nationwide Cohort Study
Denissoff A; Taipale H; Tiihonen J; Di Forti M; Mittendorfer-Rutz E; Tanskanen A; Mustonen A; Niemela S
Article: SCHIZOPHRENIA BULLETIN. 2024;50(6):1471-1481
Antipsychotic Use and Risk of Breast Cancer in Women With Severe Mental Illness: Replication of a Nationwide Nested Case-Control Database Study
Solmi M; Laehteenvuo M; Tanskanen A; Corbeil O; Mittendorfer-Rutz E; Correll CU; Tiihonen J; Taipale H
Article: MOLECULAR PSYCHIATRY. 2024;29(10):3128-3140
Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia
Spathopoulou A; Sauerwein GA; Marteau V; Podlesnic M; Lindlbauer T; Kipura T; Hotze M; Gabassi E; Kruszewski K; Koskuvi M; Rethelyi JM; Apati A; Conti L; Ku M; Koal T; Mueller U; Talmazan RA; Ojansuu I; Vaurio O; Lahteenvuo M; Lehtonen S; Mertens J; Kwiatkowski M; Gunther K; Tiihonen J; Koistinaho J; Trajanoski Z; Edenhofer F
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2024;181(10):893-900
Real-World Effectiveness of Menopausal Hormone Therapy in Preventing Relapse in Women With Schizophrenia or Schizoaffective Disorder
Brand BA; Sommer IE; Gangadin SS; Tanskanen A; Tiihonen J; Taipale H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2024;181(10):879-892
High Burden of Ileus and Pneumonia in Clozapine-Treated Individuals With Schizophrenia: A Finnish 25-Year Follow-Up Register Study
Partanen JJ; Happola P; Kampe A; Ahola-Olli A; Hellsten A; Rask SM; Haaki W; Hietala J; Kampman O; Tiihonen J; Tanskanen AJ; Daly MJ; Ripatti S; Palotie A; Taipale H; Lahteenvuo M; Koskela JT
Article: JAMA NETWORK OPEN. 2024;7(10):e2438358
Comparative Effectiveness of Antipsychotics in Patients With Schizophrenia Spectrum Disorder
Hamina A; Taipale H; Lieslehto J; Laehteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Article: JAMA PSYCHIATRY. 2024;81(10):967-975
Pneumonia Risk, Antipsychotic Dosing, and Anticholinergic Burden in Schizophrenia
Luykx JJ; Correll CU; Manu P; Tanskanen A; Hasan A; Tiihonen J; Taipale H
Article: BJPSYCH OPEN. 2024;10(5):e158
Characteristics of high-dose benzodiazepine use: nationwide cohort study on new benzodiazepine users with 5-year follow-up
Sarkila H; Taipale H; Tanskanen A; Kurko T; Taiminen T; Tiihonen J; Sund R; Saastamoinen L; Hietala J; Niemela S
Article: MOLECULAR PSYCHIATRY. 2024;29(9):2622-2633
Genetic contribution to microglial activation in schizophrenia
Koskuvi M; Poersti E; Hewitt T; Raesaenen N; Wu Y-C; Trontti K; Mcquade A; Kalyanaraman S; Ojansuu I; Vaurio O; Cannon TD; Loennqvist J; Therman S; Suvisaari J; Kaprio J; Blurton-Jones M; Hovatta I; Laehteenvuo M; Rolova T; Lehtonen S; Tiihonen J; Koistinaho J
Article: SCHIZOPHRENIA RESEARCH: COGNITION. 2024;37:100316
Association of obesity to reaction time and visual memory in schizophrenia
Toimela JS; Halt AH; Kerkela M; Kampman O; Suvisaari J; Kieseppa T; Lahteenvuo M; Tiihonen J; Ahola-Olli A; Veijola J; Holm M
Article: PSYCHIATRY RESEARCH. 2024;339:116012
Dopamine D2 receptor antagonism of antipsychotics and the risk of death due to choking
Luykx JJ; Tanskanen A; Lahteenvuo M; Manu P; Correll CU; Hasan A; Lieslehto J; Taipale H; Tiihonen J
Article: NEUROIMAGE. 2024;297:120724
Aberrant type 2 dopamine receptor availability in violent offenders with psychopathy
Lukkarinen L; Tuisku J; Sun L; Helin S; Karlsson HK; Venetjoki N; Salomaa M; Rautio P; Hirvonen J; Lauerma H; Tiihonen J; Nummenmaa L
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2024;150(2):56-64
Cardiovascular mortality in bipolar disorder: Population-based cohort study
Paljarvi T; Herttua K; Taipale H; Lahteenvuo M; Tanskanen A; Tiihonen J
Article: BIOLOGICAL PSYCHIATRY GLOBAL OPEN SCIENCE. 2024;4(4):100313
Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner
Rasanen N; Tiihonen J; Koskuvi M; Lehtonen S; Jalkanen N; Karmila N; Weert I; Vaurio O; Ojansuu I; Lahteenvuo M; Pietilainen O; Koistinaho J
Article: LANCET PSYCHIATRY. 2024;11(6):443-450
Long-term persistence of the risk of agranulocytosis with clozapine compared with other antipsychotics: a nationwide cohort and case-control study in Finland
Rubio JM; Kane JM; Tanskanen A; Tiihonen J; Taipale H
Article: WORLD PSYCHIATRY. 2024;23(2):276-284
Real-world effectiveness of antidepressants, antipsychotics and their combinations in the maintenance treatment of psychotic depression. Evidence from within-subject analyses of two nationwide cohorts
Taipale H; Lieslehto J; Laehteenvuo M; Hamina A; Tanskanen A; Mittendorfer-Rutz E; Paljaervi T; Solmi M; Cipriani A; Correll CU; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2024;267:230-238
Antipsychotic medications and sleep problems in patients with schizophrenia
Cederlof E; Holm M; Taipale H; Tiihonen J; Tanskanen A; Lahteenvuo M; Lahdensuo K; Kampman O; Wegelius A; Isometsa E; Kieseppa T; Palotie A; Suvisaari J; Paunio T
Article: EUROPEAN PSYCHIATRY. 2024;67(1):e34
Long-term benzodiazepine use and risk of labor market marginalization in Finland: A cohort study with 5-year follow-up
Taipale H; Tanskanen A; Kurko T; Taiminen T; Sarkila H; Tiihonen J; Sund R; Niemela S; Saastamoinen L; Hietala J
Article: SCHIZOPHRENIA RESEARCH. 2024;266:118-126
Association of antidepressant and benzodiazepine use, and anticholinergic burden with cognitive performance in schizophrenia
Makipelto V; Tuulio-Henriksson A; Hakulinen C; Niemela S; Lahteenvuo M; Wegeliusbd A; Kieseppab T; Isometsa E; Tiihonen J; Kampman O; Lahdensuo K; Mazumder A; Suvisaari J; Holm M
Article: JAMA NETWORK OPEN. 2024;7(3):e240640
Development and Validation of a Machine Learning-Based Model of Mortality Risk in First-Episode Psychosis
Lieslehto J; Tiihonen J; Laehteenvuo M; Leucht S; Correll CU; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Article: JOURNAL OF PSYCHIATRY & NEUROSCIENCE. 2024;49(2):E87-E95
Navigated and individual α-peak-frequency-guided transcranial magnetic stimulation in male patients with treatment-refractory schizophrenia
Tuppurainen H; Maatta S; Kononen M; Julkunen P; Kautiainen H; Hyvarinen S; Vaurio O; Joensuu M; Vanhanen M; Aho-Mustonen K; Mervaala E; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2024;264:526-533
Characteristics of incident substance-induced psychosis compared to first-episode psychotic disorders: A nationwide register-linkage study from Sweden
Jeyapalan J; Sassi P; Rutz EM; Tiihonen J; Taipale H; Niemela S
Article: LANCET PSYCHIATRY. 2024;11(2):102-111
Efficacy and effectiveness of antipsychotics in schizophrenia: network meta-analyses combining evidence from randomised controlled trials and real-world data
Efthimiou O; Taipale H; Radua J; Schneider-Thoma J; Pinzon-Espinosa J; Ortuno M; Vinkers CH; Mittendorfer-Rutz E; Cardoner N; Tanskanen A; Fusar-Poli P; Cipriani A; Vieta E; Leucht S; Tiihonen J; Luykx JJ
Article: FRONTIERS IN PSYCHIATRY. 2024;15:1372687
Association of duration of treatment on post-discharge mortality in forensic psychiatric patients in Finland
Ojansuu I; Forsman J; Kautiainen H; Seppanen A; Tiihonen J; Lahteenvuo M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2024;149(1):41-51
Effect of severity of depression on augmentation of antidepressant medication in young adults with depression
Lampela P; Tanskanen A; Lahteenvuo M; Tiihonen J; Taipale H
Article: CLINICAL EPIDEMIOLOGY. 2023;15:695-705
I32-Adrenoceptor Agonists in Asthma or Chronic Obstructive Pulmonary Disease and Risk of Parkinson's Disease: Nested Case-Control Study
Paakinaho A; Tiihonen M; Koskela H; Koponen M; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: PSYCHIATRY RESEARCH. 2023;330:115539
Comprehensive dissection of prevalence rates, sex differences, and blood level-dependencies of clozapine-associated adverse drug reactions.
van der Horst MZ; Meijer Y; de Boer N; Guloksuz S; Hasan A; Siskind D; Wagner E; CLOZIN consortium; Okhuijsen-Pfeifer C; Luykx JJ
Article: SCHIZOPHRENIA BULLETIN. 2023;49(6):1568-1578
Effects of Substance Use and Antisocial Personality on Neuroimaging-Based Machine Learning Prediction of Schizophrenia
Taipale M; Tiihonen J; Korhonen J; Popovic D; Vaurio O; Lahteenvuo M; Lieslehto J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;340:237-244
Real-world use of pharmacological treatments for incident bipolar disorder: A Finnish nationwide cohort study
Koistinaho A; Poranen J; Tanskanen A; Tiihonen J; Taipale H; Lahteenvuo M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;148(5):416-425
Use of antipsychotics and antidepressants in first-episode psychotic depression: A nationwide register-based study
Hamina A; Paljarvi T; Tanskanen A; Lahteenvuo M; Tiihonen J; Taipale H
Article: BRITISH JOURNAL OF PSYCHIATRY. 2023;223(4):456-464
Real-world effectiveness of pharmacological treatments for bipolar disorder: register-based national cohort study
Lahteenvuo M; Paljarvi T; Tanskanen A; Taipale H; Tiihonen J
Article: LANCET PSYCHIATRY. 2023;10(8):644-652
An international research agenda for clozapine-resistant schizophrenia
Luykx JJ; Gonzalez -Diaz JM; Guu T-W; van der Horst MZ; van Dellen E; Boks MP; Guloksuz S; Delisi LE; Sommer IE; Cummins R; Shiers D; Lee J; Every-Palmer S; Mhalla A; Chadly Z; Chan SKW; Cotes R; Takahashi S; Benros ME; Wagner E; Correll CU; Hasan A; Siskind D; Endres D; MacCabet J; Tiihonen J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;333:403-408
Non-adherence to mood stabilizers and antipsychotics among persons with bipolar disorder-A nationwide cohort study
Lintunen J; Lahteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2023;49(4):962-972
Clozapine Optimization: A Delphi Consensus Guideline From the Treatment Response and Resistance in Psychosis Working Group.
Wagner E; Siskind D; Falkai P; Howes O; Correll C; Lee J; Honer WG; Kane JM; Fernandez-Egea E; Barnes TRE; Hasan A; TRRIP Working Group
Article: JAMA NETWORK OPEN. 2023;6(6):e2317130
Comparative Effectiveness of Pharmacotherapies for the Risk of Attempted or Completed Suicide Among Persons With Borderline Personality Disorder
Lieslehto J; Tiihonen J; Lahteenvuo M; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;147(6):603-613
Association of pharmacological treatments and real-world outcomes in borderline personality disorder
Lieslehto J; Tiihonen J; Lahteenvuo M; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Article: SCHIZOPHRENIA. 2023;9(1):34
Real-world effectiveness of antidepressant use in persons with schizophrenia: within-individual study of 61,889 subjects
Puranen A; Koponen M; Laehteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(5):377-385
Safety of Antipsychotic Polypharmacy Versus Monotherapy in a Nationwide Cohort of 61,889 Patients With Schizophrenia
Taipale H; Tanskanen A; Tiihonen J
Article: BMJ MENTAL HEALTH. 2023;26(1):e300700
Cause-specific excess mortality after first diagnosis of bipolar disorder: population-based cohort study
Paljarvi T; Herttua K; Taipale H; Lahteenvuo M; Tanskanen A; Fazel S; Tiihonen J
Article: BMJ OPEN. 2023;13(4):e070710
Cohort profile: SUPER-Finland - the Finnish study for hereditary mechanisms of psychotic disorders
Lahteenvuo M; Ahola-Olli A; Suokas K; Holm M; Misiewicz Z; Jukuri T; Maennynsalo T; Wegelius A; Haaki W; Kajanne R; Kyttala A; Tuulio-Henriksson A; Lahdensuo K; Hakkinen K; Hietala J; Paunio T; Niemi-Pynttari J; Kieseppa T; Veijola J; Lonnqvist J; Isometsa E; Kampman O; Tiihonen J; Hyman S; Neale B; Daly M; Suvisaari J; Palotie A
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;326:249-261
Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults
Solmi M; Thompson T; Estrade A; Agorastos A; Radua J; Cortese S; Dragioti E; Leisch F; Vancampfort D; Thygesen LC; Aschauer H; Schloegelhofer M; Aschauer E; Schneeberger A; Huber CG; Hasler G; Conus P; Do Cuenod KQ; von Kaenel R; Arrondo G; Fusar-Poli P; Gorwood P; Llorca P-M; Krebs M-O; Scanferla E; Kishimoto T; Rabbani G; Skonieczna-Zydecka K; Brambilla P; Favaro A; Takamiya A; Zoccante L; Colizzi M; Bourgin J; Kaminski K; Moghadasin M; Seedat S; Matthews E; Wells J; Vassilopoulou E; Gadelha A; Su K-P; Kwon JS; Kim M; Lee TY; Papsuev O; Mankova D; Boscutti A; Gerunda C; Saccon D; Righi E; Monaco F; Croatto G; Cereda G; Demurtas J; Brondino N; Veronese N; Enrico P; Politi P; Ciappolino V; Pfennig A; Bechdolf A; Meyer-Lindenberg A; Kahl KG; Domschke K; Bauer M; Koutsouleris N; Winter S; Borgwardt S; Bitter I; Balazs J; Czobor P; Unoka Z; Mavridis D; Tsamakis K; Bozikas VP; Tunvirachaisakul C; Maes M; Rungnirundorn T; Supasitthumrong T; Haque A; Brunoni AR; Costardi CG; Schuch FB; Polanczyk G; Luiz JM; Fonseca L; Aparicio LV; Valvassori SS; Nordentoft M; Vendsborg P; Hoffmann SH; Sehli J; Sartorius N; Heuss S; Guinart D; Hamilton J; Kane J; Rubio J; Sand M; Koyanagi A; Solanes A; Andreu-Bernabeu A; Jose Caceres AS; Arango C; Diaz-Caneja CM; Hidalgo-Mazzei D; Vieta E; Gonzalez-Penas J; Fortea L; Parellada M; Fullana MA; Verdolini N; Andrlikova E; Janku K; Millan MJ; Honciuc M; Moniuszko-Malinowska A; Loniewski I; Samochowiec J; Kiszkiel L; Marlicz M; Sowa P; Marlicz W; Spies G; Stubbs B; Firth J; Sullivan S; Darcin AE; Aksu H; Dilbaz N; Noyan O; Kitazawa M; Kurokawa S; Tazawa Y; Anselmi A; Cracco C; Ines Machado A; Estrade N; De Leo D; Curtis J; Berk M; Ward P; Teasdale S; Rosenbaum S; Marx W; Horodnic AV; Oprea L; Alexinschi O; Ifteni P; Turliuc S; Ciuhodaru T; Bolos A; Matei V; Nieman DH; Sommer I; van Os J; van Amelsvoort T; Sun C-F; Guu T-W; Jiao C; Zhang J; Fan J; Zou L; Yu X; Chi X; de Timary P; van Winkel R; Ng B; Pena E; Arellano R; Roman R; Sanchez T; Movina L; Morgado P; Brissos S; Aizberg O; Mosina A; Krinitski D; Mugisha J; Sadeghi-Bahmani D; Sheybani F; Sadeghi M; Hadi S; Brand S; Errazuriz A; Crossley N; Ristic DI; Lopez-Jaramillo C; Efthymiou D; Kuttichira P; Kallivayalil RA; Javed A; Afridi MI; James B; Seb-Akahomen OJ; Fiedorowicz J; Carvalho AF; Daskalakis J; Yatham LN; Yang L; Okasha T; Dahdouh A; Gerdle B; Tiihonen J; Shin JI; Lee J; Mhalla A; Gaha L; Brahim T; Altynbekov K; Negay N; Nurmagambetova S; Abu Jamei Y; Weiser M; Correll CU
Article: MOLECULAR PHARMACEUTICS. 2023;20(3):1500-1508
Functional Characterization of Six SLCO1B1 (OATP1B1) Variants Observed in Finnish Individuals with a Psychotic Disorder
Hakkinen K; Kiander W; Kidron H; Lahteenvuo M; Urpa L; Lintunen J; Vellonen K-S; Auriola S; Holm M; Lahdensuo K; Kampman O; Isometsa E; Kieseppa T; Lonnqvist J; Suvisaari J; Hietala J; Tiihonen J; Palotie A; Ahola-Olli AV; Niemi M
Journal article: EUROPEAN PSYCHIATRY. 2023;66:s442
Psychotic depression and the risk of death due to suicide
Paljarvi T; Tiihonen J; Lahteenvuo M; Tanskanen A; Fazel S; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2023;147(3):257-266
Real-world effectiveness of mood stabilizer use in schizophrenia
Puranen A; Koponen M; Lahteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Article: JAMA PSYCHIATRY. 2023;80(2):181-185
Associations Between Polygenic Risk Score Loading, Psychosis Liability, and Clozapine Use Among Individuals With Schizophrenia
Lin BD; Pinzon-Espinosa J; Blouzard E; van der Horst MZ; Okhuijsen-Pfeifer C; van Eijk KR; Guloksuz S; Peyrot WJ; Luykx JJ
Article: JAMA PSYCHIATRY. 2023;80(2):167-175
Association of Treatment-Resistant Depression With Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study
Lundberg J; Cars T; Loeoev S-A; Soederling J; Sundstroem J; Tiihonen J; Leval A; Gannedahl A; Bjoerkholm C; Sjaelin M; Hellner C
Article: PSYCHOLOGICAL MEDICINE. 2023;53(3):833-843
Continuity of antipsychotic medication use among migrant and Finnish-born populations with a psychotic disorder: a register-based study
Lehti V; Taipale H; Gissler M; Tanskanen A; Elonheimo M; Tiihonen J; Suvisaari J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2023;321:28-32
Psychotic depression and deaths due to suicide
Paljarvi T; Tiihonen J; Lateenvuo M; Tanskanen A; Fazel S; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2023;49(1):78-89
Antipsychotic Use and Risk of Low-Energy Fractures in People With Schizophrenia: A Nationwide Nested Case-Control Study in Finland
Solmi M; Lahteenvuo M; Correll CU; Tanskanen A; Tiihonen J; Taipale H
Article: SCHIZOPHRENIA BULLETIN. 2023;49(1):136-143
Women with Schizophrenia-Spectrum Disorders After Menopause: A Vulnerable Group for Relapse
Sommer IE; Brand BA; Gangadin S; Tanskanen A; Tiihonen J; Taipale H
Journal article: NEUROSCIENCE APPLIED. 2023;2:102808
Antipsychotics and mood stabilizers in bipolar disorder – associations between dosing levels and the risk of relapse and treatment safety
Lintunen J; Hamina A; Lähteenvuo M; Paljärvi T; Tanskanen A; Tiihonen J; Taipale H
Article: SCHIZOPHRENIA BULLETIN OPEN. 2023;4(1):sgac073
Substance Use and Sleep Problems in Patients With Psychotic Disorders
Cederlof E; Holm M; Ahti J; Lahteenvuo M; Hietala J; Hakkinen K; Isometsa E; Kampman O; Lahdensuo K; Lonnqvist J; Suvisaari J; Tiihonen J; Wegelius A; Veijola J; Palotie A; Kieseppa T; Niemela S; Paunio T
Article: BRITISH JOURNAL OF PSYCHIATRY. 2023;222(1):37-43
Mortality in psychotic depression: 18-year follow-up study
Paljarvi T; Tiihonen J; Lahteenvuo M; Tanskanen A; Fazel S; Taipale H
Article: FRONTIERS IN PSYCHIATRY. 2023;14:1157171
General and violent recidivism of former forensic psychiatric patients in Finland
Ojansuu I; Latvala A; Kautiainen H; Forsman J; Tiihonen J; Lahteenvuo M
Article: JAMA PSYCHIATRY. 2023;80(1):31-39
Association of Pharmacological Treatments and Hospitalization and Death in Individuals With Amphetamine Use Disorders in a Swedish Nationwide Cohort of 13 965 Patients
Heikkinen M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Lahteenvuo M; Tiihonen J
Journal article: NEUROSCIENCE APPLIED. 2023;2:103551
Kynurenic acid promotes activity-dependent synaptic pruning and associates with genetic risk variance for schizophrenia
Orhan F; Malwade S; Schwieler L; Tiihonen J; Koistinahu J; Erhardt S; Engberg G; Kent J; Samudyata S; Sellgren C
Journal article: NEUROSCIENCE APPLIED. 2023;2:102444
Machine learning model to estimate mortality risk after the first episode of bipolar disorder
Lieslehto J; Tiihonen J; Lähteenvuo M; Kautzky A; Akhtar A; Ármannsdóttir B; Leucht S; Correll C; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Journal article: NEUROSCIENCE APPLIED. 2023;2:103017
Comparative real-world effectiveness of antipsychotics for relapse prevention in schizophrenia-spectrum disorders
Hamina A; Taipale H; Lieslehto J; Lähteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Journal article: NEUROSCIENCE APPLIED. 2023;2:103032
Leveraging machine learning for personalized pharmacotherapy to prevent future relapse in first-episode psychosis: a risk-based approach in real-world nationwide datasets
Lieslehto J; Tiihonen J; Lähteenvuo M; Leucht S; Correll C; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Journal article: NEUROSCIENCE APPLIED. 2023;2:102631
Use of antipsychotics and antidepressants in first-episode psychotic depression – a nationwide register-based study
Hamina A; Paljärvi T; Tanskanen A; Lähteenvuo M; Tiihonen J; Taipale H
Journal article: NEUROSCIENCE APPLIED. 2023;2:103088
Real-world effectiveness of antidepressants and antipsychotics in treatment of psychotic depression
Taipale H; Lieslehto J; Lähteenvuo M; Hamina A; Mittendorfer-Rutz E; Paljärvi T; Tiihonen J
Article: CEREBRAL CORTEX. 2022;33(2):374-384
Aberrant motor contagion of emotions in psychopathy and high-functioning autism
Sun L; Lukkarinen L; Noppari T; Nazari-Farsani S; Putkinen V; Seppala K; Hudson M; Tani P; Lindberg N; Karlsson HK; Hirvonen J; Salomaa M; Venetjoki N; Lauerma H; Tiihonen J; Nummenmaa L
Article: SCHIZOPHRENIA RESEARCH. 2022;250:67-75
Factors and their weight in reducing life expectancy in schizophrenia
Correll CU; Bitter I; Hoti F; Mehtala J; Wooller A; Pungor K; Tiihonen J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2022;146(6):583-593
Twenty-year medication use trends in first-episode bipolar disorder
Poranen J; Koistinaho A; Tanskanen A; Tiihonen J; Taipale H; Lahteenvuo M
Article: BRITISH JOURNAL OF PSYCHIATRY. 2022;221(6):758-765
Associations between antipsychotic use, substance use and relapse risk in patients with schizophrenia: real-world evidence from two national cohorts
Laehteenvuo M; Luykx JJ; Taipale H; Mittendorfer-Rutz E; Tanskanen A; Batalla A; Tiihonen J
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2022;179(12):938-946
Effectiveness of Antipsychotic Use for Reducing Risk of Work Disability: Results From a Within-Subject Analysis of a Swedish National Cohort of 21,551 Patients With First-Episode Nonaffective Psychosis
Solmi M; Taipale H; Holm M; Tanskanen A; Mittendorfer-Rutz E; Correll CU; Tiihonen J
Article: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 2022;377(1863):20210181
Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans
Sun L; Lukkarinen L; Putkinen V; Karlsson HK; Hirvonen J; Tiihonen J; Lauerma H; Scott S; Nummenmaa L
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;313:43-48
Allopurinol, dipyridamole and calcium channel blockers in the treatment of bipolar disorder - A nationwide cohort study
Lintunen J; Lahteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;61:36-42
Comparative effectiveness of mood stabilizers and antipsychotics in the prevention of hospitalization after lithium discontinuation in bipolar disorder
Holm M; Tanskanen A; Lahteenvuo M; Tiihonen J; Taipale H
Article: BMC PSYCHIATRY. 2022;22(1):484
Healthcare utilization, costs, and productivity losses in treatment-resistant depression in Finland - a matched cohort study
Taipale H; Lahteenvuo M; Tanskanen A; Huoponen S; Rannanpaa S; Tiihonen J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2022;146(1):51-63
Clinical and societal burden of incident major depressive disorder: A population-wide cohort study in Stockholm
Lundberg J; Cars T; Loov S-A; Soderling J; Tiihonen J; Leval A; Gannedahl A; Bjorkholm C; Sjalin M; Hellner C
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;308:236-242
Courses of treatment and risk factors for treatment-resistant depression in Finnish primary and special healthcare: A nationwide cohort study
Lahteenvuo M; Taipale H; Tanskanen A; Rannanpaa S; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2022;48(4):774-784
Optimal Doses of Specific Antipsychotics for Relapse Prevention in a Nationwide Cohort of Patients with Schizophrenia
Taipale H; Tanskanen A; Luykx JJ; Solmi M; Leucht S; Correll CU; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2022;244:10-17
Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study
Ahti J; Kieseppa T; Suvisaari J; Suokas K; Holm M; Wegelius A; Ahola-Olli A; Hakkinen K; Kampman O; Lahteenvuo M; Paunio T; Tiihonen J; Tuulio-Henriksson A; Isometsa E
Journal article: EUROPEAN PSYCHIATRY. 2022;65(Suppl 1):s268
Healthcare costs and productivity losses in treatment-resistant depression in Finland
Rannanpää S; Taipale H; Tanskanen A; Lähteenvuo M; Huoponen S; Tiihonen J
Article: ADDICTION. 2022;117(6):1683-1691
Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort
Heikkinen M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Lahteenvuo M; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2022;48(3):655-663
Primary Nonadherence to Antipsychotic Treatment Among Persons with Schizophrenia
Lieslehto J; Tiihonen J; Lahteenvuo M; Tanskanen A; Taipale H
Article: PHARMACOGENOMICS JOURNAL. 2022;22(3):166-172
Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder
Hakkinen K; Kiiski JI; Lahteenvuo M; Jukuri T; Suokas K; Niemi-Pynttari J; Kieseppa T; Mannynsalo T; Wegelius A; Haaki W; Lahdensuo K; Kajanne R; Kaunisto MA; Tuulio-Henriksson A; Kampman O; Hietala J; Veijola J; Lonnqvist J; Isometsa E; Paunio T; Suvisaari J; Kalso E; Niemi M; Tiihonen J; Daly M; Palotie A; Ahola-Olli AV
Article: LANCET PSYCHIATRY. 2022;9(5):353-362
Long-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland
Tiihonen J; Tanskanen A; Bell JS; Dawson JL; Kataja V; Taipale H
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):145
Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders
Okhuijsen-Pfeifer C; van der Horst MZ; Bousman CA; Lin B; van Eijk KR; Ripke S; Ayhan Y; Babaoglu MO; Bak M; Alink W; van Beek H; Beld E; Bouhuis A; Edlinger M; Erdogan IM; Ertugrul A; Yoca G; Everall P; Goerlitz T; Grootens KP; Gutwinski S; Hallikainen T; Jeger-Land E; de Koning M; Lahteenvuo M; Legge SE; Leucht S; Morgenroth C; Muderrisoglu A; Narang A; Pantelis C; Pardinas AF; Oviedo-Salcedo T; Schneider-Thoma J; Schreiter S; Repo-Tiihonen E; Tuppurainen H; Veereschild M; Veerman S; de Vos M; Wagner E; Cohen D; Bogers JPAM; Walters JTR; Yagcioglu EA; Tiihonen J; Hasan A; Luykx JJ
Article: GLIA. 2022;70(4):650-660
Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia
Koskuvi M; Lehtonen S; Trontti K; Keuters M; Wu Y-C; Koivisto H; Ludwig A; Plotnikova L; Virtanen PLJ; Rasanen N; Kaipainen S; Hyotylainen I; Dhungana H; Giniatullina R; Ojansuu I; Vaurio O; Cannon TD; Lonnqvist J; Therman S; Suvisaari J; Kaprio J; Lahteenvuo M; Tohka J; Giniatullin R; Rivera C; Hovatta I; Tanila H; Tiihonen J; Koistinaho J
Article: LANCET PSYCHIATRY. 2022;9(4):271-279
Real-world effectiveness of antipsychotic doses for relapse prevention in patients with first-episode schizophrenia in Finland: a nationwide, register-based cohort study
Taipale H; Tanskanen A; Correll CU; Tiihonen J
Article: JAMA PSYCHIATRY. 2022;79(3):210-218
Representation and Outcomes of Individuals With Schizophrenia Seen in Everyday Practice Who Are Ineligible for Randomized Clinical Trials
Taipale H; Schneider-Thoma J; Pinzon-Espinosa J; Radua J; Efthimiou O; Vinkers CH; Mittendorfer-Rutz E; Cardoner N; Pintor L; Tanskanen A; Tomlinson A; Fusar-Poli P; Cipriani A; Vieta E; Leucht S; Tiihonen J; Luykx JJ
Article: JOURNAL OF AFFECTIVE DISORDERS. 2022;299:367-376
Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times-Children and Adolescents (COH-FIT-C&A)
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The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic
Solmi M; Estrade A; Thompson T; Agorastos A; Radua J; Cortese S; Dragioti E; Leisch F; Vancampfort D; Thygesen LC; Aschauer H; Schloegelhofer M; Akimova E; Schneeberger A; Huber CG; Hasler G; Conus P; Do Cuenod KQ; von Kanel R; Arrondo G; Fusar-Poli P; Gorwood P; Llorca P-M; Krebs M-O; Scanferla E; Kishimoto T; Rabbani G; Skonieczna-Zydecka K; Brambilla P; Favaro A; Takamiya A; Zoccante L; Colizzi M; Bourgin J; Kaminski K; Moghadasin M; Seedat S; Matthews E; Wells J; Vassilopoulou E; Gadelha A; Su K-P; Kwon JS; Kim M; Lee TY; Papsuev O; Mankova D; Boscutti A; Gerunda C; Saccon D; Righi E; Monaco F; Croatto G; Cereda G; Demurtas J; Brondino N; Veronese N; Enrico P; Politi P; Ciappolino V; Pfennig A; Bechdolf A; Meyer-Lindenberg A; Kahl KG; Domschke K; Bauer M; Koutsouleris N; Winter S; Borgwardt S; Bitter I; Balazs J; Czobor P; Unoka Z; Mavridis D; Tsamakis K; Bozikas VP; Tunvirachaisakul C; Maes M; Rungnirundorn T; Supasitthumrong T; Haque A; Brunoni AR; Costardi CG; Schuch FB; Polanczyk G; Luiz JM; Fonseca L; Aparicio LV; Valvassori SS; Nordentoft M; Vendsborg P; Hoffmann SH; Sehli J; Sartorius N; Heuss S; Guinart D; Hamilton J; Kane J; Rubio J; Sand M; Koyanagi A; Solanes A; Andreu-Bernabeu A; San Jose Caceres A; Arango C; Diaz-Caneja CM; Hidalgo-Mazzei D; Vieta E; Gonzalez-Penas J; Fortea L; Parellada M; Fullana MA; Verdolini N; Farkova E; Janku K; Millan M; Honciuc M; Moniuszko-Malinowska A; Loniewski I; Samochowiec J; Kiszkiel L; Marlicz M; Sowa P; Marlicz W; Spies G; Stubbs B; Firth J; Sullivan S; Darcin AE; Aksu H; Dilbaz N; Noyan O; Kitazawa M; Kurokawa S; Tazawa Y; Anselmi A; Cracco C; Ines Machado A; Estrade N; De Leo D; Curtis J; Berk M; Ward P; Teasdale S; Rosenbaum S; Marx W; Horodnic AV; Oprea L; Alexinschi O; Ifteni P; Turliuc S; Ciuhodaru T; Bolos A; Matei V; Nieman DH; Sommer I; van Os J; van Amelsvoort T; Sun C-F; Guu T-W; Jiao C; Zhang J; Fan J; Zou L; Yu X; Chi X; de Timary P; van Winke R; Ng B; Pena E; Arellano R; Roman R; Sanchez T; Movina L; Morgado P; Brissos S; Aizberg O; Mosina A; Krinitski D; Mugisha J; Sadeghi-Bahmani D; Sadeghi M; Hadi S; Brand S; Errazuriz A; Crossley N; Ristic DI; Lopez-Jaramillo C; Efthymiou D; Kuttichira P; Kallivayalil RA; Javed A; Afridi MI; James B; Seb-Akahomen OJ; Fiedorowicz J; Carvalho AF; Daskalakis J; Yatham LN; Yang L; Okasha T; Dahdouh A; Gerdle B; Tiihonen J; Shin JI; Lee J; Mhalla A; Gaha L; Brahim T; Altynbekov K; Negay N; Nurmagambetova S; Abu Jamei Y; Weiser M; Correll CU
Article: JOURNAL OF PSYCHIATRIC AND MENTAL HEALTH NURSING. 2022;29(1):36-47
Voluntary patient safety incidents reporting in forensic psychiatry-What do the reports tell us?
Kuosmanen A; Tiihonen J; Repo-Tiihonen E; Turunen H
Article: SCHIZOPHRENIA BULLETIN. 2022;48(1):166-175
Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study
Solmi M; Tiihonen J; Lahteenvuo M; Tanskanen A; Correll CU; Taipale H
Article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 2022;33(1):172-177
Exploring the relation between high-activity COMT Val158Met genotype and psychopathy in male offenders
Pauli M; Olund Alonso H; Liljeberg J; Gustavsson P; Tiihonen J; Howner K
Article: FRONTIERS IN PSYCHIATRY. 2022;13:831410
Female Psychopathy and Mortality
Vaurio O; Laehteenvuo M; Kautiainen H; Repo-Tiihonen E; Tiihonen J
Journal article: NEUROSCIENCE APPLIED. 2022;1:100845
Real-world effectiveness of pharmacological treatments of borderline personality disorder – a nationwide cohort study
Lieslehto J; Tiihonen J; Lähteenvuo M; Mittendorfer-Rutz E; Tanskanen A; Taipale H
Journal article: NEUROSCIENCE APPLIED. 2022;1:100640
Effectiveness of antipsychotics on work disability in persons with first-episode non-affective psychosis
Solmi M; Taipale H; Holm M; Tanskanen A; Mittendorfer-Rutz E; Correll CU; Tiihonen J
Journal article: NEUROSCIENCE APPLIED. 2022;1:100284
Safety of antipsychotic polypharmacy versus monotherapy in specific dose categories in a nation-wide cohort of 61,889 patients with schizophrenia
Taipale H; Tanskanen A; Tiihonen J
Journal article: SCHIZOPHRENIA BULLETIN OPEN. 2022;3(1):sgac011
Sleep in Psychotic Disorders: Results From Nationwide SUPER Finland Study
Cederlof E; Holm M; Lahteenvuo M; Haaki W; Hietala J; Hakkinen K; Isometsa E; Jukuri T; Kajanne R; Kampman O; Kieseppa T; Lahdensuo K; Lonnqvist J; Mannynsalo T; Niemi-Pynttari J; Suokas K; Suvisaari J; Tiihonen J; Turunen H; Wegelius A; Veijola J; Palotie A; Paunio T
Journal article: SCHIZOPHRENIA BULLETIN OPEN. 2022;3(1):sgac021
Psychosis and the Risk of Stranger Homicides
Ojansuu I; Lahteenvuo M; Tiihonen J; Lehti M; Putkonen H
Article: NEUROIMAGE-CLINICAL. 2022;35:103116
Brain structural alterations in autism and criminal psychopathy
Noppari T; Sun L; Lukkarinen L; Putkinen V; Tani P; Lindberg N; Saure E; Lauerma H; Tiihonen J; Venetjoki N; Salomaa M; Rautio P; Hirvonen J; Salmi J; Nummenmaa L
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;295:1474-1481
Switches and early discontinuations of antidepressant medication in young adults with depression
Lampela P; Tanskanen A; Lahteenvuo M; Tiihonen J; Taipale H
Article: JOURNAL OF NEURAL TRANSMISSION. 2021;128(11):1721-1739
Associations of age, sex, sexual abuse, and genotype with monoamine oxidase a gene methylation
Checknita D; Tiihonen J; Hodgins S; Nilsson KW
Article: ADDICTION BIOLOGY. 2021;26(6):e13035
Changes in the metabolic profile of human male postmortem frontal cortex and cerebrospinal fluid samples associated with heavy alcohol use
Karkkainen O; Kokla M; Lehtonen M; Auriola S; Martiskainen M; Tiihonen J; Karhunen PJ; Hanhineva K; Kok E
Article: BRAIN SCIENCES. 2021;11(11):1422
Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder
Mazumder AH; Barnett J; Isometsae ET; Lindberg N; Torniainen-Holm M; Laehteenvuo M; Lahdensuo K; Kerkelae M; Ahola-Olli A; Hietala J; Kampman O; Kieseppae T; Jukuri T; Haekkinen K; Cederloef E; Haaki W; Kajanne R; Wegelius A; Maennynsalo T; Niemi-Pynttaeri J; Suokas K; Loennqvist J; Tiihonen J; Paunio T; Vainio SJ; Palotie A; Niemelae S; Suvisaari J; Veijola J
Article: SCHIZOPHRENIA BULLETIN. 2021;47(6):1621-1630
Risk Factors, Incidence, and Outcomes of Neuroleptic Malignant Syndrome on Long-Acting Injectable vs Oral Antipsychotics in a Nationwide Schizophrenia Cohort
Guinart D; Taipale H; Rubio JM; Tanskanen A; Correll CU; Tiihonen J; Kane JM
Article: SCHIZOPHRENIA BULLETIN. 2021;47(6):1611-1620
Long-term Continuity of Antipsychotic Treatment for Schizophrenia: A Nationwide Study
Rubio JM; Taipale H; Tanskanen A; Correll CU; Kane JM; Tiihonen J
Article: LANCET PSYCHIATRY. 2021;8(10):883-891
Antipsychotic use and risk of breast cancer in women with schizophrenia: a nationwide nested case-control study in Finland
Taipale H; Solmi M; Lahteenvuo M; Tanskanen A; Correll CU; Tiihonen J
Article: BRAIN SCIENCES. 2021;11(9):1154
Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder
Mazumder AH; Barnett J; Isometsa ET; Lindberg N; Torniainen-Holm M; Lahteenvuo M; Lahdensuo K; Kerkela M; Ahola-Olli A; Hietala J; Kampman O; Kieseppa T; Jukuri T; Hakkinen K; Cederlof E; Haaki W; Kajanne R; Wegelius A; Mannynsalo T; Niemi-Pynttari J; Suokas K; Lonnqvist J; Tiihonen J; Paunio T; Vainio SJ; Palotie A; Niemela S; Suvisaari J; Veijola J
Article: ADDICTION. 2021;116(8):1990-1998
Real-world effectiveness of pharmacological treatments of alcohol use disorders in a Swedish nation-wide cohort of 125 556 patients
Heikkinen M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Lahteenvuo M; Tiihonen J
Article: CEREBRAL CORTEX. 2021;31(9):4104-4114
Brain Basis of Psychopathy in Criminal Offenders and General Population
Nummenmaa L; Lukkarinen L; Sun L; Putkinen V; Seppala K; Karjalainen T; Karlsson HK; Hudson M; Venetjoki N; Salomaa M; Rautio P; Hirvonen J; Lauerma H; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2021;47(4):1099-1107
Long-Term Real-World Effectiveness of Pharmacotherapies for Schizoaffective Disorder
Lintunen J; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J; Lahteenvuo M
Article: NORDIC JOURNAL OF PSYCHIATRY. 2021;75(5):315-322
Antipsychotic use among persons with schizophrenia in Sweden and Finland, trends and differences
Taipale H; Puranen A; Mittendorfer-Rutz E; Tiihonen J; Tanskanen A; Cervenka S; Lahteenvuo M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2021;144(1):42-49
Morbidity and mortality in schizophrenia with comorbid substance use disorders
Lahteenvuo M; Batalla A; Luykx JJ; Mittendorfer-Rutz E; Tanskanen A; Tiihonen J; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2021;143(6):487-494
Incidence of schizophrenia and influence of prenatal and infant exposure to viral infectious diseases
Tanskanen A; Taipale H; Cannon M; Cotter D; Tiihonen J
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2021;56(6):1025-1034
Risk of labour market marginalisation among young refugees and non-refugee migrants with common mental disorders
Di Thiene D; Helgesson M; Rahman S; Alexanderson K; Tiihonen J; La Torre G; Mittendorfer-Rutz E
Article: SCHIZOPHRENIA RESEARCH. 2021;232:33-41
Molecular signaling pathways underlying schizophrenia
Tiihonen J; Koskuvi M; Lahteenvuo M; Trontti K; Ojansuu I; Vaurio O; Cannon DT; Lonnqvist J; Therman S; Suvisaari J; Cheng L; Tanskanen A; Taipale H; Lehtonen A; Koistinaho J
Article: BRAIN SCIENCES. 2021;11(6):688
Reaction Time and Visual Memory in Connection with Alcohol Use in Schizophrenia and Schizoaffective Disorder
Mazumder AH; Barnett J; Lindberg N; Torniainen-Holm M; Lahteenvuo M; Lahdensuo K; Kerkela M; Hietala J; Isometsa ET; Kampman O; Kieseppa T; Jukuri T; Hakkinen K; Cederlof E; Haaki W; Kajanne R; Wegelius A; Mannynsalo T; Niemi-Pynttari J; Suokas K; Lonnqvist J; Niemela S; Tiihonen J; Paunio T; Palotie A; Suvisaari J; Veijola J
Article: CLINICAL EPIDEMIOLOGY. 2021;13:295-307
Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer's Disease
Pisa F; Reinold J; Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):214
HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry
Konte B; Walters JTR; Rujescu D; Legge SE; Pardinas AF; Cohen D; Pirmohamed M; Tiihonen J; Hartmann AM; Bogers JP; van der Weide J; van der Weide K; Putkonen A; Repo-Tiihonen E; Hallikainen T; Silva E; Ingimarsson O; Sigurdsson E; Kennedy JL; Sullivan PF; Rietschel M; Breen G; Stefansson H; Stefansson K; Collier DA; O'Donovan MC; Giegling I
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;45:35-37
Registry-based studies: What they can tell us, and what they cannot
Taipale H; Tiihonen J
Article: JOURNAL OF PATIENT SAFETY. 2021;17(3):e228-e233
Nurses' Views Highlight a Need for the Systematic Development of Patient Safety Culture in Forensic Psychiatry Nursing
Kuosmanen A; Tiihonen J; Repo-Tiihonen E; Eronen M; Turunen H
Article: SCHIZOPHRENIA RESEARCH. 2021;228:367-372
Effectiveness of pharmacotherapies for delusional disorder in a Swedish national cohort of 9076 patients
Lahteenvuo M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2021;47(1):23-30
Comparative Effectiveness of Antipsychotics for Risk of Attempted or Completed Suicide Among Persons With Schizophrenia
Taipale H; Lahteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Article: NPJ SCHIZOPHRENIA. 2021;7(1):1
Adenosine modulators and calcium channel blockers as add-on treatment for schizophrenia
Lintunen J; Lahteenvuo M; Tiihonen J; Tanskanen A; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2021;143(1):61-71
Employment among people with schizophrenia or bipolar disorder: A population-based study using nationwide registers
Holm M; Taipale H; Tanskanen A; Tiihonen J; Mitterdorfer-Rutz E
Article: MOLECULAR PSYCHIATRY. 2020;25(12):3432-3441
Neurobiological roots of psychopathy
Tiihonen J; Koskuvi M; Lahteenvuo M; Virtanen PLJ; Ojansuu I; Vaurio O; Gao Y; Hyotylainen I; Puttonen KA; Repo-Tiihonen E; Paunio T; Rautiainen M-R; Tyni S; Koistinaho J; Lehtonen S
Article: JOURNAL OF AFFECTIVE DISORDERS. 2020;277:885-892
Suicide mortality and use of psychotropic drugs in patients hospitalized due to bipolar disorder: A Finnish nationwide cohort study
Antolin-Concha D; Lahteenvuo M; Vattulainen P; Tanskanen A; Taipale H; Vieta E; Tiihonen J
Article: BMC GERIATRICS. 2020;20(1):441
Causes of death in a nationwide cohort of community-dwellers with Alzheimer's disease
Tolppanen A-M; Taipale H; Koponen M; Tiihonen J; Hartikainen S
Article: CTS-CLINICAL AND TRANSLATIONAL SCIENCE. 2020;13(6):1170-1177
Persistence of Antipsychotic Use After Clozapine Discontinuation: A Real-World Study Across Antipsychotics
Stam N; Taipale H; Tanskanen A; Isphording L; Okhuijsen-Pfeifer C; Schuiling-Veninga CCM; Bos JHJ; Bijker BJ; Tiihonen J; Luykx JJ
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2020;75(11):2184-2192
Length of Hospital Stay for Hip Fracture and 30-Day Mortality in People With Alzheimer's Disease: A Cohort Study in Finland
Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JAMA NETWORK OPEN. 2020;3(10):e2019029
Incidence of and Characteristics Associated With Long-term Benzodiazepine Use in Finland
Taipale H; Sarkila H; Tanskanen A; Kurko T; Taiminen T; Tiihonen J; Sund R; Tuulio-Henriksson A; Saastamoinen L; Hietala J
Article: LANCET PSYCHIATRY. 2020;7(9):749-761
Psychosis relapse during treatment with long-acting injectable antipsychotics in individuals with schizophrenia-spectrum disorders: an individual participant data meta-analysis
Rubio JM; Schoretsanitis G; John M; Tiihonen J; Taipale H; Guinart D; Malhotra AK; Correll CU; Kane JM
Article: BRITISH JOURNAL OF PSYCHIATRY. 2020;217(3):498-505
In the aftermath of clozapine discontinuation: comparative effectiveness and safety of antipsychotics in patients with schizophrenia who discontinue clozapine
Luykx JJ; Stam N; Tanskanen A; Tiihonen J; Taipale H
Article: INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS. 2020;141:104142
Detection of medications associated with Alzheimer's disease using ensemble methods and cooperative game theory
Braithwaite B; Paananen J; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: MEDICAL CARE. 2020;58(9):763-769
Medication Use and Health Care Utilization After a Cost-sharing Increase in Schizophrenia A Nationwide Analysis
Hamina A; Tanskanen A; Tiihonen J; Taipale H
Journal article: THE PRIMARY CARE COMPANION FOR CNS DISORDERS. 2020;22(3):19l02542
Valproate and Neuroleptic Malignant Syndrome in an Elderly Patient With Schizoaffective Disorder.
Lindeman S; Kolari T; Tiihonen J
Article: PSYCHOLOGICAL MEDICINE. 2020;50(8):1356-1367
Psychosis breakthrough on antipsychotic maintenance: results from a nationwide study
Rubio JM; Taipale H; Correll CU; Tanskanen A; Kane JM; Tiihonen J
Article: NEUROLOGY. 2020;94(20):e2099-e2108
Antiepileptic drug use and mortality among community-dwelling persons with Alzheimer disease
Sarycheva T; Lavikainen P; Taipale H; Tiihonen J; Tanskanen A; Hartikainen S; Tolppanen A-M
Journal article: SCHIZOPHRENIA BULLETIN. 2020;46(Supplement_1):s118-s119
S210. COMPARATIVE EFFECTIVENESS OF ANTIPSYCHOTICS FOR RISK OF ATTEMPTED OR COMPLETED SUICIDE AMONG PERSONS WITH SCHIZOPHRENIA
Taipale H; Lähteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Journal article: SCHIZOPHRENIA BULLETIN. 2020;46(Supplement_1):s311-s312
T208. EFFECTIVENESS OF PHARMACOLOGICAL THERAPIES FOR DELUSIONAL DISORDER
Lähteenvuo M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Journal article: SCHIZOPHRENIA BULLETIN. 2020;46(Supplement_1):s250
T49. SOCIODEMOGRAPHIC AND LIFESTYLE FACTORS ASSOCIATED WITH GOOD PERFORMANCE IN PAIRED ASSOCIATES LEARNING TEST IN PATIENTS WITH SCHIZOPHRENIA
Taivalantti M; Barnett J; Torniainen M; Haaki W; Hietala J; Isometsä E; Joutsenniemi K; Jukuri T; Kajanne R; Kampman O; Kieseppä T; Lindberg N; Lähteenvuo M; Lönnqvist J; Suokas K; Suvisaari J; Tiihonen J; Paunio T; Halt A-H; Kerkelä M; Järvelin M-R; Tuulio-Henriksson A; Daly M; Veijola J; Palotie A
Article: BMC PSYCHIATRY. 2020;20(1):232
Risk and risk factors for disability pension among patients with treatment resistant depression- a matched cohort study
Taipale H; Reutfors J; Tanskanen A; Brandt L; Tiihonen J; DiBernardo A; Mittendorfer-Rutz E; Brenner P
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2020;76(5):711-718
Use of antidepressants and mood stabilizers in persons with first-episode schizophrenia
Puranen A; Koponen M; Tanskanen A; Tiihonen J; Taipale H
Article: NPJ SCHIZOPHRENIA. 2020;6(1):12
The clinical course of schizophrenia in women and men-a nation-wide cohort study
Sommer IE; Tiihonen J; van Mourik A; Tanskanen A; Taipale H
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2020;105(4):dgz234-e972
Metformin and Risk of Alzheimer's Disease Among Community-Dwelling People With Diabetes: A National Case-Control Study
Sluggett JK; Koponen M; Bell JS; Taipale H; Tanskanen A; Tiihonen J; Uusitupa M; Tolppanen A-M; Hartikainen S
Article: BEHAVIOURAL BRAIN RESEARCH. 2020;382:112476
Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour
Checknita D; Bendre M; Ekstrom TJ; Comasco E; Tiihonen J; Hodgins S; Nilsson KW
Article: DRUGS & AGING. 2020;37(3):193-203
Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease
Lintula E; Tiihonen M; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Hamina A
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2020;68(3):595-602
The Risk of Head Injuries Associated With Antipsychotic Use Among Persons With Alzheimer's disease
Tapiainen V; Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;73(3):1243-1251
Asthma and Chronic Obstructive Pulmonary Disease as a Comorbidity and Association with the Choice of Antidementia Medication Among Persons with Alzheimer's Disease
Lampela P; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: WORLD PSYCHIATRY. 2020;19(1):61-68
20-year follow-up study of physical morbidity and mortality in relationship to antipsychotic treatment in a nationwide cohort of 62,250 patients with schizophrenia (FIN20)
Taipale H; Tanskanen A; Mehtala J; Vattulainen P; Correll CU; Tiihonen J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2020;300:221-225
Prevalence of cardiovascular drug use before and after diagnosis of Alzheimer's disease
Vu M; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Kettunen R; Hartikainen S; Tolppanen A-M
Article: SCIENTIFIC REPORTS. 2020;10(1):1219
Health and work disability outcomes in parents of patients with schizophrenia associated with antipsychotic exposure by the offspring
Taipale H; Rahman S; Tanskanen A; Mehtala J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tiihonen J; Mittendorfer-Rutz E
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s549
P.825 Twenty year follow-up study on antipsychotic treatment, physical morbidity, and mortality in a nationwide cohort of 62,250 patients with schizophrenia (FIN20)
Taipale H; Tanskanen A; Mehtälä J; Vattulainen P; Correll CU; Tiihonen J
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2019;29(6):1055-1062
Trajectories of sickness absence, disability pension and unemployment in young immigrants with common mental disorders
Di Thiene D; Mittendorfer-Rutz E; Rahman S; Wang M; Alexanderson K; Tiihonen J; La Torre G; Helgesson M
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2019;20(12):1488-1494.e3
Accumulation of Hospital Days Among Antipsychotic Initiators With Alzheimer's Disease
Koponen M; Lavikainen P; Taipale H; Lic ATP; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75(10):1421-1430
Adherence to psychotropic medication in completed suicide in Sweden 2006-2013: a forensic-toxicological matched case-control study
Forsman J; Taipale H; Masterman T; Tiihonen J; Tanskanen A
Article: NATURE COMMUNICATIONS. 2019;10(1):3933
Sex-specific transcriptional and proteomic signatures in schizophrenia
Tiihonen J; Koskuvi M; Storvik M; Hyotylainen I; Gao Y; Puttonen KA; Giniatullina R; Poguzhelskaya E; Ojansuu I; Vaurio O; Cannon TD; Lonnqvist J; Therman S; Suvisaari J; Kaprio J; Cheng L; Hill AF; Lahteenvuo M; Tohka J; Giniatullin R; Lehtonen S; Koistinaho J
Article: ANNALS OF MEDICINE. 2019;51(5-6):294-305
Predictors of high hospital care and medication costs and cost trajectories in community-dwellers with Alzheimer's disease
Kalamagi J; Lavikainen P; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2019;289:37-44
Cortical structure abnormalities in females with conduct disorder prior to age 15
Budhiraja M; Pereira JB; Lindner P; Westman E; Jokinen J; Savic I; Tiihonen J; Hodgins S
Article: OSTEOPOROSIS INTERNATIONAL. 2019;30(7):1481-1489
Long-term thiazide use and risk of low-energy fractures among persons with Alzheimer's disease-nested case-control study
Taipale H; Rysa J; Hukkanen J; Koponen M; Tanskanen A; Tiihonen J; Kroger H; Hartikainen S; Tolppanen A-M
Article: SCHIZOPHRENIA BULLETIN. 2019;45(4):794-803
Burden for Parents of Patients With Schizophrenia-A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls
Mittendorfer-Rutz E; Rahman S; Tanskanen A; Majak M; Mehtala J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Taipale H; Tiihonen J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;69(3):807-816
Hospital-Treated Pneumonia Associated with Opioid Use Among Community Dwellers with Alzheimer's Disease
Hamina A; Taipale H; Karttunen N; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2019;20(6):751-758
Antiepileptic Drugs and Accumulation of Hospital Days Among Persons With Alzheimer's Disease
Lavikainen P; Taipale H; Tanskanen A; Koponen M; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2019;287:63-69
Increased [³H] quisqualic acid binding density in the dorsal striatum and anterior insula of alcoholics: A post-mortem whole-hemisphere autoradiography study
Laukkanen V; Karkkainen O; Kautiainen H; Tiihonen J; Storvik M
Article: JOURNAL OF NURSING MANAGEMENT. 2019;27(4):848-857
Changes in patient safety culture: A patient safety intervention for Finnish forensic psychiatric hospital staff
Kuosmanen A; Tiihonen J; Repo-Tiihonen E; Eronen M; Turunen H
Article: JAMA PSYCHIATRY. 2019;76(5):499-507
Association of Antipsychotic Polypharmacy vs Monotherapy With Psychiatric Rehospitalization Among Adults With Schizophrenia
Tiihonen J; Taipale H; Mehtala J; Vattulainen P; Correll CU; Tanskanen A
Article: JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH. 2019;73(5):451-454
Incidence of head injury and traumatic brain injury among people with Alzheimer's disease
Ilmaniemi S; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2019;68(1):127-136
Antiepileptic Drug Use Is Associated with an Increased Risk of Pneumonia Among Community-Dwelling Persons with Alzheimer's Disease-Matched Cohort Study
Taipale H; Lampela P; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75(3):417-425
Duration of new antidepressant use and factors associated with discontinuation among community-dwelling persons with Alzheimer's disease
Kettunen R; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Koponen M
Article: PAIN. 2019;160(2):417-423
Incident opioid use and risk of hip fracture among persons with Alzheimer disease: a nationwide matched cohort study
Taipale H; Hamina A; Karttunen N; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2019;34(2):280-288
Concomitant use of benzodiazepines and opioids in community-dwelling older people with or without Alzheimer's disease-A nationwide register-based study in Finland
Karttunen N; Taipale H; Hamina A; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Article: FRONTIERS IN PSYCHIATRY. 2019;10:678
Substance Abuse and Excessive Mortality Among Forensic Psychiatric Patients: A Finnish Nationwide Cohort Study
Ojansuu I; Putkonen H; Lahteenvuo M; Tiihonen J
Journal article: DIGITAL PSYCHIATRY. 2019;2(1):14-24
Manifesto for an international digital mental health network
Maron E; Baldwin DS; Balõtšev R; Fabbri C; Gaur V; Hidalgo-Mazzei D; Hood S; Juhola M; Kampman O; Kasper S; Kärkkäinen H; Látalová K; Lähteenvuo M; Mastellos N; McTigue J; Metsallik J; Metspalu A; Nutt D; Nykänen P; Olisa N; Pogarell O; Popovic D; Ramos-Quiroga JA; Ross P; Serretti A; Spies M; Thibaut F; Tiainen K; Tiihonen J; Vieta E; Võhma Ü; Van Westrhenen R; Zubanovic B; Eberhard J
Article: BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING. 2018;3(12):1003-1012
Associations of Psychopathic Traits With Local and Global Brain Network Topology in Young Adult Women
Lindner P; Flodin P; Budhiraja M; Savic I; Jokinen J; Tiihonen J; Hodgins S
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2018;138(6):492-499
Mortality in schizophrenia: 30-year nationwide follow-up study
Tanskanen A; Tiihonen J; Taipale H
Article: SUBSTANCE ABUSE TREATMENT PREVENTION AND POLICY. 2018;13(1):39
Comorbid opioid use is undertreated among forensic patients with schizophrenia
Kivimies K; Repo-Tiihonen E; Kautiainen H; Tiihonen J
Article: DRUGS & AGING. 2018;35(11):985-992
Systemic Estrogen Use and Discontinuation After Alzheimer's Disease Diagnosis in Finland 2005-2012: A Nationwide Exposure-Matched Cohort Study
Tolppanen A-M; Tiihonen M; Taipale H; Koponen M; Tanskanen A; Lavikainen P; Tiihonen J; Hartikainen S
Article: BIPOLAR DISORDERS. 2018;20(7):634-646
Initiation and long-term use of benzodiazepines and Z-drugs in bipolar disorder
Wingard L; Taipale H; Reutfors J; Westerlund A; Boden R; Tiihonen J; Tanskanen A; Andersen M
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2018;28(11):1260-1269
Psychotropic drugs use and psychotropic polypharmacy among persons with Alzheimer's disease
Orsel K; Taipale H; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Gardarsdottir H; Hartikainen S
Article: PAIN MEDICINE. 2018;19(11):2115-2121
Is Alzheimer's Disease Associated with Previous Opioid Use?
Taipale H; Hamina A; Lampela P; Tanskanen A; Tiihonen J; Karttunen N; Tolppanen A-M; Hartikainen S
Article: SCHIZOPHRENIA BULLETIN. 2018;44(6):1381-1387
Comparative Effectiveness of Antipsychotic Drugs for Rehospitalization in Schizophrenia-A Nationwide Study With 20-Year Follow-up
Taipale H; Mehtala J; Tanskanen A; Tiihonen J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;66(1):387-395
Incidence and Prevalence of Antiepileptic Medication Use in Community-Dwelling Persons with and without Alzheimer's Disease
Sarychevaa T; Taipale H; Lavikainen P; Tiihonen J; Tanskanen A; Hartikainen S; Tolppanen A-M
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2018;38(5):494-497
Antipsychotic Use and the Risk of Initiating Medication for Benign Prostate Hyperplasia in Persons With Alzheimer Disease: A Matched Cohort Study
Orsel K; Taipale H; Raatikainen S; Lampela P; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Gardarsdottir H; Hartikainen S
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27(10):1112-1122
Comparison of dispensed medications and forensic-toxicological findings to assess pharmacotherapy in the Swedish population 2006 to 2013
Forsman J; Taipale H; Masterman T; Tiihonen J; Tanskanen A
Journal article: 2018
Suicide mortality and use of psychotropic drugs in patients hospitalized due to bipolar disorder: a Finnish nationwide cohort study
Lähteenvuo M; Tiihonen J
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2018;7(18):e009742
Antiepileptic Drug Use and the Risk of Stroke Among Community-Dwelling People With Alzheimer Disease: A Matched Cohort Study
Sarycheva T; Lavikainen P; Taipale H; Tiihonen J; Tanskanen A; Hartikainen S; Tolppanen A-M
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(8):765-773
20-Year Nationwide Follow-Up Study on Discontinuation of Antipsychotic Treatment in First-Episode Schizophrenia
Tiihonen J; Tanskanen A; Taipale H
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2018;138(2):91-100
The risk of Alzheimer's disease associated with benzodiazepines and related drugs: a nested case-control study
Tapiainen V; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: NORDIC JOURNAL OF PSYCHIATRY. 2018;72(5):374-379
Cause-specific mortality in Finnish forensic psychiatric patients
Ojansuu I; Putkonen H; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2018;197:274-280
Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Taipale H; Mittendorfer-Rutz E; Alexanderson K; Majak M; Mehtala J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Tiihonen J
Article: JOURNAL OF NEURAL TRANSMISSION. 2018;125(7):1053-1064
Associations of monoamine oxidase A gene first exon methylation with sexual abuse and current depression in women
Checknita D; Ekstrom TJ; Comasco E; Nilsson KW; Tiihonen J; Hodgins S
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2018;66(6):1123-1129
Use of Antiepileptic Drugs and Dementia Riskan Analysis of Finnish Health Register and German Health Insurance Data
Taipale H; Gomm W; Broich K; Maier W; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Haenisch B
Article: INTERNATIONAL PSYCHOGERIATRICS. 2018;30(7):947-956
Impact of opioid initiation on antipsychotic and benzodiazepine and related drug use among persons with Alzheimer's disease
Hamina A; Lavikainen P; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S; Taipale H
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;64(2):437-445
Hospitalization after Oral Antibiotic Initiation in Finnish Community Dwellers with and without Alzheimer's Disease: Retrospective Register-Based Cohort Study
Jarvinen H; Taipale H; Koponen M; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27(6):674-682
Trends in the long-term use of benzodiazepine anxiolytics and hypnotics: A national register study for 2006 to 2014
Kurko T; Saastamoinen LK; Tuulio-Henriksson A; Taiminen T; Tiihonen J; Airaksinen M; Hietala J
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2018;28(3):445-451
Healthcare use among immigrants and natives in Sweden on disability pension, before and after changes of regulations
Di Thiene D; Rahman S; Helgesson M; Wang M; Alexanderson K; Tiihonen J; La Torre G; Mittendorfer-Rutz E
Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2018;28(suppl_1):cky047.258
7.4-O5Immigrants healthcare utilization before and after being granted disability pension due to common mental disorders: a comparison with Swedish native population
Di Thiene D; Rahman S; Helgesson M; Wang M; Alexanderson K; Tiihonen J; La Torre G; Mittendorfer-Rutz E
Article: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2018;47(8):1135-1142
Proton pump inhibitor use and risk of hip fractures among community-dwelling persons with Alzheimer's disease-a nested case-control study
Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: JAMA PSYCHIATRY. 2018;75(4):347-355
Real-world Effectiveness of Pharmacologic Treatments for the Prevention of Rehospitalization in a Finnish Nationwide Cohort of Patients With Bipolar Disorder
Lahteenvuo M; Tanskanen A; Taipale H; Hoti F; Vattulainen P; Vieta E; Tiihonen J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2018;33(4):583-590
Risk of death associated with new benzodiazepine use among persons with Alzheimer disease: A matched cohort study
Saarelainen L; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: JOURNAL OF FORENSIC SCIENCES. 2018;63(2):474-477
Psychopathy and Mortality
Vaurio O; Repo-Tiihonen E; Kautiainen H; Tiihonen J
Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2018;42(3):508-519
Associations Between MAOA-uVNTR Genotype, Maltreatment, MAOA Methylation, and Alcohol Consumption in Young Adult Males
Bendre M; Comasco E; Checknita D; Tiihonen J; Hodgins S; Nilsson KW
Article: PSYCHIATRY RESEARCH. 2018;260:173-176
Platelet monoamine oxidase activity and interpersonal violence in male suicide attempters
Jokinen J; Konigsson J; Moberg T; Jonsson EG; Tiihonen J; Nordstrom P; Oreland L; Asberg M
Article: HEART. 2018;104(4):340-348
Trajectories and characteristics of work disability before and after acute myocardial infarction
Wang M; Vaez M; Dorner TE; Tiihonen J; Voss M; Ivert T; Mittendorfer-Rutz E
Article: SCIENTIFIC REPORTS. 2018;8(1):1101
Amygdala-orbitofrontal structural and functional connectivity in females with anxiety disorders, with and without a history of conduct disorder
Lindner P; Flodin P; Larm P; Budhiraja M; Savic-Berglund I; Jokinen J; Tiihonen J; Hodgins S
Article: PSYCHIATRY RESEARCH. 2018;259:377-384
Firesetting and general criminal recidivism among a consecutive sample of Finnish pretrial male firesetters: A register-based follow-up study
Thomson A; Tiihonen J; Miettunen J; Virkkunen M; Lindberg N
Journal article: SAGE OPEN MEDICINE. 2018;6:2050312118784311
Determinants of hospitalizations for pneumonia among Finnish drug users
Olubamwo OO; Onyeka IN; Aregbesola A; Ronkainen K; Tiihonen J; Fohr J; Kauhanen J
Journal article: SAGE OPEN MEDICINE. 2018;6:2050312118768164
Diabetes hospitalizations and deaths in a cohort of treatment-seeking illicit drug users
Aregbesola A; Onyeka IN; Olubamwo O; Ronkainen K; Tiihonen J; Fohr J; Kauhanen J
Article: BMC PUBLIC HEALTH. 2017;17(1):931
Risk of disability pension in first and second generation immigrants: the role of age and region of birth in a prospective population-based study from Sweden
Di Thiene D; Helgesson M; Alexanderson K; La Torre G; Tiihonen J; Mittendorfer-Rutz E
Article: JAMA PSYCHIATRY. 2017;74(12):1242-1250
Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior
Tielbeek JJ; Johansson A; Polderman TJC; Rautiainen M-R; Jansen P; Taylor M; Tong X; Lu Q; Burt AS; Tiemeier H; Viding E; Plomin R; Martin NG; Heath AC; Madden PAF; Montgomery G; Beaver KM; Waldman I; Gelernter J; Kranzler HR; Farrer LA; Perry JRB; Munafo M; LoParo D; Paunio T; Tiihonen J; Mous SE; Pappa I; de Leeuw C; Watanabe K; Hammerschlag AR; Salvatore JE; Aliev F; Bigdeli TB; Dick D; Faraone SV; Popma A; Medland SE; Posthuma D
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2017;112(12):1802-1808
No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease
Taipale H; Tolppanen A-M; Tiihonen M; Tanskanen A; Tiihonen J; Hartikainen S
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(12):e107-e115
Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease
Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:s937-s938
P.3.d.015 Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Tiihonen J; Mittendorfer-Rutz E; Alexanderson K; Majak M; Mehtälä J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Taipale H
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:s937
P.3.d.014 Real-world effectiveness of antipsychotic treatments in a nationwide cohort of 29,823 patients
Tiihonen J; Mittendorfer-Rutz E; Majak M; Mehtälä J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Taipale H
Article: INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING. 2017;26(5):513-524
De-escalation techniques used, and reasons for seclusion and restraint, in a forensic psychiatric hospital
Kuivalainen S; Vehvilainen-Julkunen K; Louheranta O; Putkonen A; Repo-Tiihonen E; Tiihonen J
Article: SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE. 2017;12(9):1500-1510
White matter correlates of psychopathic traits in a female community sample
Lindner P; Budhiraja M; Westerman J; Savic I; Jokinen J; Tiihonen J; Hodgins S
Article: ANNALS OF PHARMACOTHERAPY. 2017;51(9):725-734
Incident Use of a Potentially Inappropriate Medication and Hip Fracture in Community-Dwelling Older Persons With Alzheimer's Disease
Hyttinen V; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Valtonen H
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2017;73(9):1149-1158
Long-term use of proton pump inhibitors among community-dwelling persons with and without Alzheimer's disease
Juntunen H; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S; Tiihonen M
Article: JOURNAL OF NERVOUS AND MENTAL DISEASE. 2017;205(8):611-617
Effects of Scheduled Waiting for Psychotherapy in Patients With Major Depression
Ahola P; Joensuu M; Knekt P; Lindfors O; Saarinen P; Tolmunen T; Valkonen-Korhonen M; Jaaskelainen T; Virtala E; Tiihonen J; Lehtonen J
Article: ALZHEIMERS RESEARCH & THERAPY. 2017;9(1):59
Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer's disease: a nationwide matched cohort study
Taipale H; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S; Tolppanen A-M
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2017;26(8):875-889
Screening approach for identifying candidate drugs and drug-drug interactions related to hip fracture risk in persons with Alzheimer disease
Tolppanen A-M; Taipale H; Koponen M; Tanskanen A; Lavikainen P; Paananen J; Tiihonen J; Hartikainen S
Article: JOURNAL OF AFFECTIVE DISORDERS. 2017;217:16-23
Reducing the rehospitalization risk after a manic episode: A population based cohort study of lithium, valproate, olanzapine,quetiapine and aripiprazole in monotherapy and combinations
Wingard L; Boden R; Brandt L; Tiihonen J; Tanskanen A; Kieler H; Andersen M; Reutfors J
Article: COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE. 2017;17(4):869-885
Brain structure abnormalities in young women who presented conduct disorder in childhood/adolescence
Budhiraja M; Savic I; Lindner P; Jokinen J; Tiihonen J; Hodgins S
Article: SCIENTIFIC REPORTS. 2017;7(1):6543
The Association of Ambient Temperature and Violent Crime
Tiihonen J; Halonen P; Tiihonen L; Kautiainen H; Storvik M; Callaway J
Article: JAMA PSYCHIATRY. 2017;74(7):686-693
Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia
Tiihonen J; Mittendorfer-Rutz E; Majak M; Mehtala J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Taipale H
Article: LANCET PSYCHIATRY. 2017;4(7):547-553
Pharmacological treatments and risk of readmission to hospital for unipolar depression in Finland: a nationwide cohort study
Tiihonen J; Tanskanen A; Hoti F; Vattulainen P; Taipale H; Mehtala J; Lahteenvuo M
Article: EUROPEAN PSYCHIATRY. 2017;43:92-98
Hospital-treated mental and behavioral disorders and risk of Alzheimer's disease: A nationwide nested case-control study
Tapiainen V; Hartikainen S; Taipale H; Tiihonen J; Tolppanen A-M
Article: INTERNATIONAL JOURNAL OF LAW AND PSYCHIATRY. 2017;52:1-6
Seasonal variation of hospital violence, seclusion and restraint in a forensic psychiatric hospital
Kuivalainen S; Vehvilainen-Julkunen K; Louheranta O; Putkonen A; Repo-Tiihonen E; Tiihonen J
Article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2017;32(3):135-141
Use of benzodiazepines and related drugs is associated with a risk of stroke among persons with Alzheimer's disease
Taipale H; Koponen M; Tanskanen A; Lavikainen P; Tolppanen A-M; Sund R; Tiihonen J; Hartikainen S
Article: CANADIAN MEDICAL ASSOCIATION JOURNAL. 2017;189(14):E519-E529
Risk of pneumonia associated with incident benzodiazepine use among community-dwelling adults with Alzheimer disease
Taipale H; Tolppanen A-M; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S
Article: ANNALS OF MEDICINE. 2017;49(3):230-239
Use of antidementia drugs and risk of pneumonia in older persons with Alzheimer's disease
Lampela P; Tolppanen A-M; Tanskanen A; Tiihonen J; Lavikainen P; Hartikainen S; Taipale H
Article: MATURITAS. 2017;98:7-13
Risk of Alzheimer's disease among users of postmenopausal hormone therapy: A nationwide case-control study
Irntiaz B; Taipale H; Tanskanen A; Tiihonen M; Kivipelto M; Heikkinen A-M; Tiihonen J; Soininen H; Hartikainen S; Tolppanen A-M
Article: EUROPEAN JOURNAL OF PAIN. 2017;21(4):658-667
Differences in analgesic use in community-dwelling persons with and without Alzheimer's disease
Hamina A; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF CLINICAL PSYCHIATRY. 2017;78(3):e257-e263
Antipsychotic Use and the Risk of Hip Fracture Among Community-Dwelling Persons With Alzheimer's Disease
Koponen M; Taipale H; Lavikainen P; Tanskanen A; Tiihonen J; Tolppanen A-M; Ahonen R; Hartikainen S
Journal article: BRAIN STIMULATION. 2017;10(2):416-417
Abnormal response to a high frequency TMS partly restores to a healthy level after rTMS treatment in Schizophrenic patients
Kallioniemi E; Määttä S; Könönen M; Julkunen P; Mervaala E; Kaarre O; Laukkanen E; Tiihonen J; Tuppurainen H
Journal article: BRAIN STIMULATION. 2017;10(2):397-398
Repetitive navigated αTMS in treatment-resistant schizophrenia
Tuppurainen H; Määttä S; Vanhanen M; Könönen M; Julkunen P; Aho-Mustonen K; Hyvärinen S; Vaurio O; Joensuu M; Repo-Tiihonen E; Mervaala E; Tiihonen J
Journal article: BRAIN STIMULATION. 2017;10(2):415
Repetition suppression in transcranial magnetic stimulation induced motor evoked potentials is impaired in schizophrenic patients
Kallioniemi E; Määttä S; Könönen M; Julkunen P; Säisänen L; Mervaala E; Kaarre O; Laukkanen E; Tiihonen J; Tuppurainen H
Article: NORDIC JOURNAL OF PSYCHIATRY. 2017;71(2):96-101
Fire-setting performed in adolescence or early adulthood predicts schizophrenia: a register-based follow-up study of pre-trial offenders
Thomson A; Tiihonen J; Miettunen J; Virkkunen M; Lindberg N
Article: PAIN. 2017;158(2):252-260
Long-term use of opioids for nonmalignant pain among community-dwelling persons with and without Alzheimer disease in Finland: a nationwide register-based study
Hamina A; Taipale H; Tanskanen A; Tolppanen A-M; Karttunen N; Pylkkanen L; Tiihonen J; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;56(1):119-128
Anticholinergic Exposure and Risk of Pneumonia in Persons with Alzheimer's Disease: A Nested Case-Control Study
Lampela P; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;56(1):107-118
Risk of Mortality Associated with Antipsychotic Monotherapy and Polypharmacy Among Community-Dwelling Persons with Alzheimer's Disease
Koponen M; Taipale H; Lavikainen P; Tanskanen A; Tiihonen J; Tolppanen A-M; Ahonen R; Hartikainen S
Article: NORDIC JOURNAL OF PSYCHIATRY. 2017;71(1):77-80
Add-on mirtazapine improves orgasmic functioning in patients with schizophrenia treated with first-generation antipsychotics
Terevnikov V; Stenberg J-H; Tiihonen J; Burkin M; Joffe G
Journal article: SAGE OPEN MEDICINE. 2017;5:2050312117740987
Association between route of illicit drug administration and hospitalizations for infective endocarditis
Olubamwo O; Onyeka IN; Aregbesola A; Ronkainen K; Tiihonen J; Fohr J; Kauhanen J
Article: DRUGS & AGING. 2017;34(1):55-65
A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland
Moga DC; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Wu Q; Jicha GA; Gnjidic D
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2017;18(1):87.e15-87.e21
Risk of Hip Fracture in Benzodiazepine Users With and Without Alzheimer Disease
Saarelainen L; Tolppanen A-M; Koponen M; Phil AT; Sund R; Tiihonen J; Hartikainen S; Taipale H
Article: DRUGS & AGING. 2017;34(1):67-77
Risk Factors for Initiation of Potentially Inappropriate Medications in Community-Dwelling Older Adults with and without Alzheimer's Disease
Hyttinen V; Taipale H; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S; Valtonen H
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(1):94-101
Incidence of antidepressant use in community-dwelling persons with and without Alzheimer's disease: 13-year follow-up
Puranen A; Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: PLOS ONE. 2017;12(9):e0184070
Drug exposure in register-based research-An expert-opinion based evaluation of methods
Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Article: PLOS ONE. 2017;12(3):e0173450
Regional changes in psychotropic use among Finnish persons with newly diagnosed Alzheimer's disease in 2005-2011
Tolppanen A-M; Voutilainen A; Taipale H; Tanskanen A; Lavikainen P; Koponen M; Tiihonen J; Hartikainen S
Article: CRIMINAL BEHAVIOUR AND MENTAL HEALTH. 2016;26(5):395-402
Hospital-treated suicide attempts among Finnish fire setters: a follow-up study
Thomson A; Tiihonen J; Miettunen J; Virkkunen M; Lindberg N
Article: BMC GERIATRICS. 2016;16(1):204
Comparison of predictors of hip fracture and mortality after hip fracture in community-dwellers with and without Alzheimer's disease - exposure-matched cohort study
Tolppanen A-M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S
Article: CHEST. 2016;150(6):1233-1241
Antipsychotic Use and Risk of Hospitalization or Death Due to Pneumonia in Persons With and Those Without Alzheimer Disease
Tolppanen A-M; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S; Taipale H
Journal article: JOURNAL OF SUBSTANCE USE. 2016;21(6):559-565
Association between routes of drug administration and all-cause mortality among drug users
Onyeka IN; Basnetl S; Beynon CM; Tiihonen J; Fohr J; Kauhanenl J
Article: AGE AND AGEING. 2016;45(6):900-904
Drug use in persons with and without Alzheimer's disease aged 90 years or more
Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: CLINICAL EPIDEMIOLOGY. 2016;8:363-371
Agreement between PRE2DUP register data modeling method and comprehensive drug use interview among older persons
Taipale H; Tanskanen A; Koponen M; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES. 2016;124(9):529-534
Influence of a HTR2B Stop Codon on Glucagon Homeostasis and Glucose Excursion in Non-Diabetic Men
Tikkanen R; Saukkonen T; Fex M; Bennet H; Rautiainen M-R; Paunio T; Koskinen M; Panarsky R; Bevilacqua L; Sjoberg RL; Tiihonen J; Virkkunen M
Journal article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES. 2016;124(9):e5
Correction: Influence of a HTR2B Stop Codon on Glucagon Homeostasis and Glucose Excursion in Non-Diabetic Men.
Tikkanen R; Saukkonen T; Fex M; Bennet H; Rautiainen M-R; Paunio T; Koskinen M; Panarsky R; Bevilacqua L; Sjöberg RL; Tiihonen J; Virkkunen M
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2016;81:79-86
The effects of a HTR2B stop codon and testosterone on energy metabolism and beta cell function among antisocial Finnish males
Tikkanen R; Saukkonen T; Fex M; Bennet H; Rautiainen M-R; Paunio T; Koskinen M; Panarsky R; Bevilacqua L; Sjoberg RL; Tiihonen J; Virkkunen M
Article: TRANSLATIONAL PSYCHIATRY. 2016;6(9):e883
Genome-wide association study of antisocial personality disorder
Rautiainen M-R; Paunio T; Repo-Tiihonen E; Virkkunen M; Ollila HM; Sulkava S; Jolanki O; Palotie A; Tiihonen J
Article: JOURNAL OF FORENSIC PSYCHOLOGY PRACTICE. 2016;16(4):253-267
Cognitive Insight, Clinical Insight, and Reasoning in Schizophrenia: A Pilot Study in a Forensic Setting
Kuokkanen R; Lappalainen R; Repo-Tiihonen E; Tiihonen J; Aho-Mustonen K
Article: BMJ OPEN. 2016;6(7):e012100
Cohort profile: the Finnish Medication and Alzheimer's disease (MEDALZ) study
Tolppanen A-M; Taipale H; Koponen M; Lavikainen P; Tanskanen A; Tiihonen J; Hartikainen S
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2016;173(6):600-606
Mortality and Cumulative Exposure to Antipsychotics, Antidepressants, and Benzodiazepines in Patients With Schizophrenia: An Observational Follow-Up Study
Tiihonen J; Mittendorfer-Rutz E; Torniainen M; Alexanderson K; Tanskanen A
Article: ALCOHOL. 2016;52:63-70
Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics
Karkkainen O; Hakkinen MR; Auriola S; Kautiainen H; Tiihonen J; Storvik M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;52(1):127-132
Incidence and Duration of Cumulative Bisphosphonate Use among Community-Dwelling Persons with or without Alzheimer's Disease
Tiihonen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S
Article: JOURNAL OF FORENSIC NURSING. 2016;12(2):64-73
Nurses' Time Use in Forensic Psychiatry: Core Interventions Outlined in the Finnish Clinical Practice Guideline on Schizophrenia
Tenkanen H; Taskinen H; Kontio R; Repo-Tiihonen E; Tiihonen J; Kinnunen J
Article: JOURNAL OF PREVENTIVE MEDICINE AND PUBLIC HEALTH. 2016;49(2):134-138
Month and Season of Birth as a Risk Factor for Alzheimer's Disease: A Nationwide Nested Case-control Study.
Tolppanen A-M; Ahonen R; Koponen M; Lavikainen P; Purhonen M; Taipale H; Tanskanen A; Tiihonen J; Tiihonen M; Hartikainen S
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2016;44(2):150-158
Hospital care and drug costs from five years before until two years after the diagnosis of Alzheimer's disease in a Finnish nationwide cohort
Taipale H; Purhonen M; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S
Article: NORDIC JOURNAL OF PSYCHIATRY. 2016;70(2):128-132
Opioid abuse and hospitalization rates in patients with schizophrenia
Kivimies K; Repo-Tiihonen E; Kautiainen H; Maaranen P; Muhonen LH; Heikkinen M; Tiihonen J
Article: TRANSLATIONAL PSYCHIATRY. 2016;6(1):e714
Conduct disorder in females is associated with reduced corpus callosum structural integrity independent of comorbid disorders and exposure to maltreatment
Lindner P; Savic I; Sitnikov R; Budhiraja M; Liu Y; Jokinen J; Tiihonen J; Hodgins S
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2016;70(1):34-41
Baseline symptom severity predicts serotonin transporter change during psychotherapy in patients with major depression
Joensuu M; Ahola P; Knekt P; Lindfors O; Saarinen P; Tolmunen T; Valkonen-Korhonen M; Vanninen R; Jaaskelainen T; Virtala E; Kuikka J; Tiihonen J; Lehtonen J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;49(3):809-818
The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer's Disease
Saarelainen L; Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen JI; Hartikainen S
Article: JOURNAL OF COMMUNITY HEALTH. 2015;40(6):1099-1106
Potential Years of Life Lost Due to Premature Mortality Among Treatment-Seeking Illicit Drug Users in Finland
Onyeka IN; Beynon CM; Vohlonen I; Tiihonen J; Fohr J; Ronkainen K; Kauhanen J
Article: TRANSLATIONAL PSYCHIATRY. 2015;5(11):e681
Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon
Tikkanen R; Tiihonen J; Rautiainen MR; Paunio T; Bevilacqua L; Panarsky R; Goldman D; Virkkunen M
Article: DRUGS & AGING. 2015;32(11):937-945
Prevalence of Drug Combinations Increasing Bleeding Risk Among Warfarin Users With and Without Alzheimer's Disease
Taipale H; Vuorikari H; Tanskanen A; Koponen M; Tiihonen J; Kettunen R; Hartikainen S
Article: BRITISH JOURNAL OF PSYCHIATRY. 2015;207(5):444-449
Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons
Koponen M; Tolppanen A-M; Taipale H; Tanskanen A; Tiihonen J; Johnell K; Fastbom J; Ahonen R; Hartikainen S
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(10):1706-1713
Long-term use of antipsychotics among community-dwelling persons with Alzheimer's disease: A nationwide register-based study
Koponen M; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Ahonen R; Hartikainen S
Journal article: EUROPEAN GERIATRIC MEDICINE. 2015;6:s19
O-050: Incidence of benzodiazepine and related drug use in persons with and without Alzheimer's disease: the MEDALZ study
Saarelainen L; Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Journal article: ALCOHOL AND ALCOHOLISM. 2015;50(suppl_1):i57
P-46MULTIVARIATE ANALYSIS OF RECEPTOR, TRANSPORTER AND NEUROTRANSMITTER LEVEL CHANGES IN POST-MORTEM BRAIN SAMPLES OF CLONINGER TYPE 1 AND 2 ALCOHOLICS
Kärkkäinen O; Tiihonen J; Storvik M
Article: JOURNAL OF AFFECTIVE DISORDERS. 2015;183:159-165
Lithium is associated with decrease in all-cause and suicide mortality in high-risk bipolar patients: A nationwide registry-based prospective cohort study
Toffol E; Hatonen T; Tanskanen A; Lonnqvist J; Wahlbeck K; Joffe G; Tiihonen J; Haukka J; Partonen T
Article: JOURNAL OF FORENSIC PSYCHOLOGY PRACTICE. 2015;15(4):344-362
A Pilot Study of Group Administered Metacognitive Training (MCT) for Schizophrenia Patients in a High-Security Forensic Setting: Subjective Training Success and Health-Related Quality of Life
Kuokkanen R; Aho-Mustonen K; Muotka J; Lappalainen R; Tiihonen J
Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2015;39(8):1352-1359
Decreased [³H]naloxone Binding in the Dentate Gyrus of Cloninger Type 1 Anxiety-Prone Alcoholics: A Postmortem Whole-Hemisphere Autoradiography Study
Laukkanen V; Karkkainen O; Kautiainen H; Tiihonen J; Storvik M
Article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2015;30(4):202-208
Long-term use of benzodiazepines and related drugs among community-dwelling individuals with and without Alzheimer's disease
Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF SUBSTANCE ABUSE TREATMENT. 2015;53:71-77
Factors Associated with Hospitalization for Blood-Borne Viral Infections Among Treatment-Seeking Illicit Drug Users
Onyeka IN; Olubamwo O; Beynon CM; Ronkainen K; Fohr J; Tiihonen J; Tuomola P; Tasa N; Kauhanen J
Article: MOLECULAR PSYCHIATRY. 2015;20(6):786-792
Genetic background of extreme violent behavior
Tiihonen J; Rautiainen M-R; Ollila HM; Repo-Tiihonen E; Virkkunen M; Palotie A; Pietilainen O; Kristiansson K; Joukamaa M; Lauerma H; Saarela J; Tyni S; Vartiainen H; Paananen J; Goldman D; Paunio T
Article: JOURNAL OF SUBSTANCE ABUSE TREATMENT. 2015;53:64-70
Hospitalization in a Cohort Seeking Treatment for Illicit Drug Use in Finland
Onyeka IN; Beynon CM; Ronkainen K; Tiihonen J; Fohr J; Kuikanmaki O; Paasolainen M; Kauhanen J
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2015;43(3):221-228
Characteristics of drug-abusing females with and without children seeking treatment in Helsinki, Finland
Basnet S; Onyeka IN; Tiihonen J; Fohr J; Kauhanen J
Article: SCHIZOPHRENIA BULLETIN. 2015;41(3):656-663
Antipsychotic Treatment and Mortality in Schizophrenia
Torniainen M; Mittendorfer-Rutz E; Tanskanen A; Bjorkenstam C; Suvisaari J; Alexanderson K; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2015;231(3):197-201
[³H]Ifenprodil binding in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study
Kupila J; Karkkainen O; Laukkanen V; Hakkinen M; Kautiainen H; Tiihonen J; Storvik M
Article: BMC MEDICAL INFORMATICS AND DECISION MAKING. 2015;15:21
From prescription drug purchases to drug use periods - a second generation method (PRE2DUP)
Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Article: BMC PSYCHIATRY. 2015;15:44
Psychopathic traits among a consecutive sample of Finnish pretrial fire-setting offenders
Thomson A; Tiihonen J; Miettunen J; Sailas E; Virkkunen M; Lindberg N
Article: PSYCHIATRY RESEARCH. 2015;225(3):420-424
Basal insulin secretion, PCL-R and recidivism among impulsive violent alcoholic offenders
Ojala KPT; Tiihonen J; Repo-Tiihonen E; Tikkanen R; Virkkunen M
Article: PSYCHIATRY RESEARCH. 2015;225(3):638-642
Mortality of firesetters: A follow-up study of Finnish male firesetters who underwent a pretrial forensic examination in 1973-1998
Thomson A; Tiihonen JI; Miettunen J; Virkkunen M; Lindberg N
Article: JOURNAL OF AFFECTIVE DISORDERS. 2015;172:204-210
Predictors for initiation of pharmacological prophylaxis in patients with newly diagnosed bipolar disorder-A nationwide cohort study
Scheen L; Brandt L; Boden R; Tiihonen J; Andersen M; Kieler H; Reutfors J
Article: NORDIC JOURNAL OF PSYCHIATRY. 2015;69(1):25-27
Mortality among forensic psychiatric patients in Finland
Ojansuu I; Putkonen H; Tiihonen J
Article: ALCOHOL AND ALCOHOLISM. 2015;50(1):46-50
Lower [³H]Citalopram Binding in Brain Areas Related to Social Cognition in Alcoholics
Karkkainen O; Laukkanen V; Haukijarvi T; Kautiainen H; Tiihonen J; Storvik M
Article: ALCOHOL AND ALCOHOLISM. 2015;50(1):62-67
Increased Metabotropic Glutamate 2/3 Receptor Binding in the Perigenual Anterior Cingulate Cortex of Cloninger Type 2 Alcoholics: A Whole-Hemisphere Autoradiography Study
Laukkanen V; Karkkainen O; Kupila J; Kautiainen H; Tiihonen J; Storvik M
Article: CRIMINAL BEHAVIOUR AND MENTAL HEALTH. 2014;24(5):345-357
Metacognitive group training for forensic and dangerous non-forensic patients with schizophrenia: A randomised controlled feasibility trial
Kuokkanen R; Lappalainen R; Repo-Tiihonen E; Tiihonen J
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2014;34(6):722-727
Concomitant Use of Acetylcholine Esterase Inhibitors and Urinary Antispasmodics Among Finnish Community-Dwelling Persons With Alzheimer Disease
Torvinen-Kiiskinen S; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S
Article: BMC RESEARCH NOTES. 2014;7:796
From prescriptions to drug use periods - things to notice.
Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Article: INTERNATIONAL JOURNAL OF DRUG POLICY. 2014;25(6):1047-1053
Patterns and 14-year trends in mortality among illicit drug users in Finland: The HUUTI study
Onyeka IN; Beynon CM; Hannila M-L; Tiihonen J; Föhr J; Tuomola P; Kuikanmäki O; Tasa N; Paasolainen M; Kauhanen J
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24(11):1729-1737
High prevalence of psychotropic drug use among persons with and without Alzheimer's disease in Finnish nationwide cohort
Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Journal article: DRUG AND ALCOHOL DEPENDENCE. 2014;142:361
Corrigendum to “Mortality among clients seeking treatment for buprenorphine abuse in Finland” [Drug Alcohol Depend. 133 (2013) 391–397]
Uosukainen H; Kauhanen J; Bell JS; Ronkainen K; Tiihonen J; Föhr J; Onyeka IN; Korhonen MJ
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2014;34(4):435-440
Antipsychotic Doses Among Community-Dwelling Persons With Alzheimer Disease in Finland
Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2014;41(4):1223-1228
Antipsychotic Polypharmacy among a Nationwide Sample of Community-Dwelling Persons with Alzheimer's Disease
Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: NORDIC JOURNAL OF PSYCHIATRY. 2014;68(5):311-315
Previous forensic mental examination is a useful marker indicating effective violence relapse prevention among psychotic patients
Kivimies K; Repo-Tiihonen E; Kautiainen H; Tiihonen J
Article: NEUROBIOLOGY OF AGING. 2014;35(7):1780.e13-1780.e17
The C9ORF72 expansion does not affect the phenotype in Nasu-Hakola disease with the DAP12 mutation
Solje E; Hartikainen P; Valori M; Vanninen R; Tiihonen J; Hakola P; Tienari PJ; Remes AM
Article: INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY. 2014;29(4):216-223
Antidementia drug use among community-dwelling individuals with Alzheimer's disease in Finland: a nationwide register-based study
Taipale H; Tanskanen A; Koponen M; Tolppanen A-M; Tiihonen J; Hartikainen S
Article: JOURNAL OF SUBSTANCE ABUSE TREATMENT. 2014;46(5):561-566
Factors associated with buprenorphine compared to amphetamine abuse among clients seeking treatment in Finland
Uosukainen H; Ilomaeki J; Kauhanen J; Tacke U; Fohr J; Tiihonen J; Bell JS
Article: JOURNAL OF PSYCHIATRIC AND MENTAL HEALTH NURSING. 2014;21(3):214-218
Violent behaviour in a forensic psychiatric hospital in Finland: an analysis of violence incident reports
Kuivalainen S; Vehvilainen-Julkunen K; Putkonen A; Louheranta O; Tiihonen J
Article: PLOS ONE. 2014;9(6):e99869
Association of Socio-Demographic Factors, Sick-Leave and Health Care Patterns with the Risk of Being Granted a Disability Pension among Psychiatric Outpatients with Depression
Mittendorfer-Rutz E; Harkanen T; Tiihonen J; Haukka J
Article: PSYCHIATRY RESEARCH. 2013;214(3):429-434
AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study
Karkkainen O; Kupila J; Hakkinen M; Laukkanen V; Tupala E; Kautiainen H; Tiihonen J; Storvik M
Article: DRUG AND ALCOHOL DEPENDENCE. 2013;133(2):391-397
Mortality among clients seeking treatment for buprenorphine abuse in Finland
Uosukainen H; Kauhanen J; Bell JS; Ronkainen K; Tiihonen J; Fohr J; Onyeka IN; Korhonen MJ
Article: JOURNAL OF FORENSIC NURSING. 2013;9(4):207-216
Patient Safety Culture in Two Finnish State-Run Forensic Psychiatric Hospitals
Kuosmanen A; Tiihonen J; Repo-Tiihonen E; Eronen M; Turunen H
Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2013;23(suppl_1):ckt126.301
Mortality among illicit drug users in Finland: findings from the HUUTI study
Onyeka I; Beynon C; Hannila M; Tiihonen J; Föhr J; Tuomola P; Kuikanmäki O; Tasa N; Paasolainen M; Kauhanen J
Journal article: EUROPEAN GERIATRIC MEDICINE. 2013;4:s208
Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons
Koponen M; Tolppanen AM; Taipale H; Tanskanen A; Tiihonen J; Johnell K; Fastbom; Ahonen R; Hartikainen S
Article: PSYCHIATRIC SERVICES. 2013;64(9):850-855
Cluster-Randomized Controlled Trial of Reducing Seclusion and Restraint in Secured Care of Men With Schizophrenia
Putkonen A; Kuivalainen S; Louheranta O; Repo-Tiihonen E; Ryynanen O-P; Kautiainen H; Tiihonen J
Journal article: EUROPEAN GERIATRIC MEDICINE. 2013;4:s202-s203
Antidementia drug use among community-dwelling persons with Alzheimer's disease in Finland–Nationwide register-based study
Taipale H; Tanskanen A; Koponen M; Tolppanen A; Tiihonen J; Hartikainen S
Article: CLINICAL EPIDEMIOLOGY. 2013;5:277-285
Use of existing data sources in clinical epidemiology: Finnish health care registers in Alzheimer's disease research - the Medication use among persons with Alzheimer's disease (MEDALZ-2005) study.
Tolppanen A-M; Taipale H; Koponen M; Lavikainen P; Tanskanen A; Tiihonen J; Hartikainen S
Article: ALCOHOL. 2013;47(5):399-403
Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics
Karkkainen OK; Lehtonen M; Laukkanen V; Tupala E; Hyytia P; Kautiainen H; Tiihonen J; Callaway JC; Storvik M
Article: BRITISH JOURNAL OF PSYCHIATRY. 2013;203(2):152-153
Cavum septum pellucidum and psychopathy
Toivonen P; Kononen M; Niskanen E; Vaurio O; Repo-Tiihonen E; Seppanen A; Aronen HJ; Vanninen R; Tiihonen J; Laakso MP
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2013;16(7):1661-1666
Relationships between pharmacotherapy-induced metabolic changes and improved psychopathology in schizophrenia: data from a mirtazapine and first-generation antipsychotics combination trial
Terevnikov V; Stenberg J-H; Tiihonen J; Chukhin E; Joffe M; Burkin M; Joffe G
Article: ADDICTION. 2013;108(7):1279-1286
Extended-release methylphenidate for treatment of amphetamine/methamphetamine dependence: a randomized, double-blind, placebo-controlled trial
Miles SW; Sheridan J; Russell B; Kydd R; Wheeler A; Walters C; Gamble G; Hardley P; Jensen M; Kuoppasalmi K; Tuomola P; Fohr J; Kuikanmaki O; Vorma H; Salokangas R; Mikkonen A; Kallio M; Kauhanen J; Kiviniemi V; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2013;212(3):245-250
mGluR1/5 receptor densities in the brains of alcoholic subjects: A whole-hemisphere autoradiography study
Kupila J; Karkkainen O; Laukkanen V; Tupala E; Tiihonen J; Storvik M
Article: BMC PUBLIC HEALTH. 2013;13:380
Coexisting social conditions and health problems among clients seeking treatment for illicit drug use in Finland: The HUUTI study
Onyeka IN; Beynon CM; Uosukainen H; Korhonen MJ; Ilomaki J; Bell JS; Paasolainen M; Tasa N; Tiihonen J; Kauhanen J
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2013;48(4):631-638
Description of long-term polypharmacy among schizophrenia outpatients
Suokas JT; Suvisaari JM; Haukka J; Korhonen P; Tiihonen J
Article: ALCOHOL. 2013;47(2):103-108
Decreased GABA_A benzodiazepine binding site densities in postmortem brains of Cloninger type 1 and 2 alcoholics
Laukkanen V; Storvik M; Hakkinen M; Akamine Y; Tupala E; Virkkunen M; Tiihonen J
Article: INTERNATIONAL JOURNAL OF LAW AND PSYCHIATRY. 2013;36(2):157-167
Atypical nucleus accumbens morphology in psychopathy: Another limbic piece in the puzzle
Boccardi M; Bocchetta M; Aronen HJ; Repo-Tiihonen E; Vaurio O; Thompson PM; Tiihonen J; Frisoni GB
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA. 2013;3(1):10-15
Word List Learning in Patients with Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy
Vanhanen M; Hakola P; Ilonen T; Tiihonen J
Article: INTERNATIONAL JOURNAL OF FORENSIC MENTAL HEALTH. 2013;12(1):1-13
Using the HCR-20 to Predict Aggressive Behavior among Men with Schizophrenia Living in the Community: Accuracy of Prediction, General and Forensic Settings, and Dynamic Risk Factors
Michel SF; Riaz M; Webster C; Hart SD; Levander S; Mueller-Isberner R; Tiihonen J; Repo-Tiihonen E; Tuninger E; Hodgins S
Article: DRUG AND ALCOHOL DEPENDENCE. 2013;127(1-3):207-214
Twelve-year trend in treatment seeking for buprenorphine abuse in Finland
Uosukainen H; Kauhanen J; Voutilainen S; Fohr J; Paasolainen M; Tiihonen J; Laitinen K; Onyeka IN; Bell JS
Article: PLOS ONE. 2013;8(1):e50303
Influence of Serotonin Transporter Gene Polymorphism (5-HTTLPR Polymorphism) on the Relation between Brain 5-HT Transporter Binding and Heart Rate Corrected Cardiac Repolarization Interval
Kauppila E; Vanninen E; Kaurijoki S; Karhunen L; Pietilainen KH; Rissanen A; Tiihonen J; Pesonen U; Kaprio J
Article: NEUROPHARMACOLOGY. 2013;64:248-253
Predictors and mediators of add-on mirtazapine-induced cognitive enhancement in schizophrenia - A path model investigation
Stenberg J-H; Terevnikov V; Joffe M; Tiihonen J; Chukhin E; Burkin M; Joffe G
Article: PSYCHOLOGICAL MEDICINE. 2012;42(11):2275-2285
Cardiovascular morbidity, mortality and pharmacotherapy in patients with schizophrenia
Lahti M; Tiihonen J; Wildgust H; Beary M; Hodgson R; Kajantie E; Osmond C; Raikkonen K; Eriksson J
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2012;21(11):1227-1231
Outcome of patients after market withdrawal of thioridazine: A retrospective analysis in a nationwide cohort
Purhonen M; Koponen H; Tiihonen J; Tanskanen A
Article: JOURNAL OF ADDICTIVE DISEASES. 2012;31(4):350-362
Sociodemographic Characteristics and Drug Abuse Patterns of Treatment-Seeking Illicit Drug Abusers in Finland, 1997-2008: The Huuti Study
Onyeka IN; Uosukainen H; Korhonen MJ; Beynon C; Bell JS; Ronkainen K; Fohr J; Tiihonen J; Kauhanen J
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;91(2):303-312
Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia
Need AC; McEvoy JP; Gennarelli M; Heinzen EL; Ge D; Maia JM; Shianna KV; He M; Cirulli ET; Gumbs CE; Zhao Q; Campbell CR; Hong L; Rosenquist P; Putkonen A; Hallikainen T; Repo-Tiihonen E; Tiihonen J; Levy DL; Meltzer HY; Goldstein DB
Journal article: ACTA NEUROPSYCHIATRICA. 2012;24(4):236-244
Rorschach assessment of personality functioning in patients with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
Ilonen T; Hakola P; Vanhanen M; Tiihonen J
Journal article: MENTAL ILLNESS. 2012;4(1):1-4
Antipsychotic polypharmacy in clozapine resistant schizophrenia: a randomized controlled trial of tapering antipsychotic co-treatment
Repo-Tiihonen E; Hallikainen T; Kivisto P; Tiihonen J
Article: AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE. 2012;38(4):273-277
The Substance Use among Forensic Psychiatric Patients
Kivimies K; Repo-Tiihonen E; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2012;202(3):264-270
Whole-hemisphere autoradiography of 5-HT_1B receptor densities in postmortem alcoholic brains
Storvik M; Hakkinen M; Tupala E; Tiihonen J
Article: ARCHIVES OF GENERAL PSYCHIATRY. 2012;69(5):476-483
Polypharmacy With Antipsychotics, Antidepressants, or Benzodiazepines and Mortality in Schizophrenia
Tiihonen J; Suokas JT; Suvisaari JM; Haukka J; Korhonen P
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2012;169(5):531-536
Naltrexone Implant for the Treatment of Polyd rug Dependence: A Randomized Controlled Trial
Tiihonen J; Krupitsky E; Verbitskaya E; Blokhina E; Mamontova O; Fohr J; Tuomola P; Kuoppasalmi K; Kiviniemi V; Zwartau E
Journal article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2012;21(3):342
Choosing an appropriate control group for an observational study design Reply
Haukka J; Niskanen L; Partonen T; Lonnqvist J; Tiihonen J
Article: BMJ OPEN. 2012;2(6):e001678
The net effect of smoking on healthcare and welfare costs. A cohort study
Tiihonen J; Ronkainen K; Kangasharju A; Kauhanen J
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2012;21(1):61-69
Statin usage and all-cause and disease-specific mortality in a nationwide study
Haukka J; Niskanen L; Partonen T; Lonnqvist J; Tiihonen J
Article: JOURNAL OF MENTAL HEALTH POLICY AND ECONOMICS. 2011;14(3):149-156
Costs of Intensive Psychiatric Care for Treatment-resistant Minors
Paakkonen T; Tiihonen J; Paakkonen H; Hallikainen T; Ryynanen O-P; Kinnunen J
Article: PSYCHIATRY RESEARCH. 2011;193(2):85-92
Cortex and amygdala morphology in psychopathy
Boccardi M; Frisoni GB; Hare RD; Cavedo E; Najt P; Pievani M; Rasser PE; Laakso MP; Aronen HJ; Repo-Tiihonen E; Vaurio O; Thompson PM; Tiihonen J
Article: JOURNAL OF PSYCHOPHARMACOLOGY. 2011;25(7):952-959
Gender differences in brain serotonin transporter availability in panic disorder
Maron E; Toru I; Hirvonen J; Tuominen L; Lumme V; Vasar V; Shlik J; Nutt DJ; Helin S; Nagren K; Tiihonen J; Hietala J
Article: CRIMINAL BEHAVIOUR AND MENTAL HEALTH. 2011;21(3):163-176
Group psychoeducation for long-term offender patients with schizophrenia: An exploratory randomised controlled trial
Aho-Mustonen K; Tiihonen J; Repo-Tiihonen E; Ryynanen O-P; Miettinen R; Raty H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2011;168(6):603-609
A Nationwide Cohort Study of Oral and Depot Antipsychotics After First Hospitalization for Schizophrenia
Tiihonen J; Haukka J; Taylor M; Haddad PM; Patel MX; Korhonen P
Article: HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL. 2011;26(3):188-193
Add-on mirtazapine improves depressive symptoms in schizophrenia: a double-blind randomized placebo-controlled study with an open-label extension phase
Terevnikov V; Stenberg J-H; Tiihonen J; Joffe M; Burkin M; Tchoukhine E; Joffe G
Article: JOURNAL OF FORENSIC NURSING. 2011;7(1):32-39
Interrelationship between core interventions and core competencies of forensic psychiatric nursing in Finland.
Tenkanen H; Tiihonen J; Repo-Tiihonen E; Kinnunen J
Article: PSYCHIATRY RESEARCH. 2011;185(3):382-386
Psychopathy, PCL-R, and MAOA genotype as predictors of violent reconvictions
Tikkanen R; Auvinen-Lintunen L; Ducci F; Sjoberg RL; Goldman D; Tiihonen J; Ojansuu I; Virkkunen M
Journal article: LANCET. 2011;377(9766):611
No mental health without physical health.
Tiihonen J; Lönnqvist J; Wahlbeck K; Klaukka T; Niskanen L; Tanskanen A; Haukka J
Article: AMERICAN JOURNAL OF PSYCHOTHERAPY. 2011;65(4):355-379
The patient-therapist interaction and the recognition of affects during the process of psychodynamic psychotherapy for depression.
Ahola P; Valkonen-Korhonen M; Tolmunen T; Joensuu M; Lehto SM; Saarinen PI; Tiihonen J; Lehtonen J
Article: HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL. 2010;25(6):431-438
More evidence on additive antipsychotic effect of adjunctive mirtazapine in schizophrenia: an extension phase of a randomized controlled trial
Terevnikov V; Stenberg J-H; Joffe M; Tiihonen J; Burkin M; Tchoukhine E; Joffe G
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2010;64(4):387-393
Serotonin-transporter-linked promoter region polymorphism and serotonin transporter binding in drug-naive patients with major depression
Joensuu M; Lehto SM; Tolmunen T; Saarinen PI; Valkonen-Korhonen M; Vanninen R; Ahola P; Tiihonen J; Kuikka J; Pesonen U; Lehtonen J
Article: NORDIC JOURNAL OF PSYCHIATRY. 2010;64(4):233-238
Extrapyramidal side-effects and dopamine D_2/3 receptor binding in substantia nigra
Tuppurainen H; Kuikka JT; Viinamaki H; Husso M; Tiihonen J
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2010;13(4):433-441
Effects of add-on mirtazapine on neurocognition in schizophrenia: a double-blind, randomized, placebo-controlled study
Stenberg J-H; Terevnikov V; Joffe M; Tiihonen J; Tchoukhine E; Burkin M; Joffe G
Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2010;34(5):853-860
MAOA Alters the Effects of Heavy Drinking and Childhood Physical Abuse on Risk for Severe Impulsive Acts of Violence Among Alcoholic Violent Offenders
Tikkanen R; Ducci F; Goldman D; Holi M; Lindberg N; Tiihonen J; Virkkunen M
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2010;20(4):245-252
Endogenous cannabinoids in post-mortem brains of Cloninger type 1 and 2 alcoholics
Lehtonen M; Storvik M; Tupala E; Hyytia P; Tiihonen J; Callaway JC
Article: HUMAN BRAIN MAPPING. 2010;31(3):438-447
Abnormal Hippocampal Shape in Offenders with Psychopathy
Boccardi M; Ganzola R; Rossi R; Sabattoli F; Laakso MP; Repo-Tiihonen E; Vaurio O; Kononen M; Aronen HJ; Thompson PM; Frisoni GB; Tiihonen J
Article: INTERNATIONAL JOURNAL OF LAW AND PSYCHIATRY. 2010;33(1):27-34
Seasonal variation of seclusion incidents from violent and suicidal acts in forensic psychiatric patients
Paavola P; Tiihonen J
Article: JOURNAL OF FORENSIC SCIENCES. 2010;55(1):116-120
The Intergenerational Cycle of Criminality-Association with Psychopathy
Repo-Tiihonen E; Tiihonen J; Lindberg N; Weizmann-Henelius G; Putkonen H; Hakkanen H
Article: JOURNAL OF PSYCHIATRIC RESEARCH. 2010;44(1):56-59
Dopamine transporter binding in females with panic disorder may vary with clinical status
Maron E; Nutt DJ; Kuikka J; Tiihonen J
Article: INTERNATIONAL JOURNAL OF CANCER. 2010;126(1):279-284
Incidence of cancer and statin usage-record linkage study
Haukka J; Sankila R; Klaukka T; Lonnqvist J; Niskanen L; Tanskanen A; Wahlbeck K; Tiihonen J
Article: INTERNATIONAL JOURNAL OF CANCER. 2010;126(1):285-296
Incidence of cancer and antidepressant medication: record linkage study
Haukka J; Sankila R; Klaukka T; Lonnqvist J; Niskanen L; Tanskanen A; Wahlbeck K; Tiihonen J
Journal article: DATA & KNOWLEDGE ENGINEERING. 2009;68(12):1427-1440
Predicting forensic admission among the mentally ill in a multinational setting: A Bayesian modelling approach
Soini EJO; Rissanen T; Tiihonen J; Hodgins S; Eronen M; Ryynanen O-P
Article: NUCLEAR MEDICINE COMMUNICATIONS. 2009;30(9):713-717
Cardiac repolarization and striatal dopamine transporter function are interrelated
Kauppila E; Vanninen E; Kuusela T; Kaurijoki S; Karhunen L; Pietilainen KH; Rissanen A; Kaprio J; Tiihonen J; Kuikka J
Article: LANCET. 2009;374(9690):620-627
11-year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study)
Tiihonen J; Lonnqvist J; Wahlbeck K; Klaukka T; Niskanen L; Tanskanen A; Haukka J
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2009;63(4):529-537
Dopamine D_2/3 receptor binding potential and occupancy in midbrain and temporal cortex by haloperidol, olanzapine and clozapine
Tuppurainen H; Kuikka JT; Viinamaki H; Husso M; Tiihonen J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2009;65(7):715-720
Antidepressant use and mortality in Finland: a register-linkage study from a nationwide cohort
Haukka J; Arffman M; Partonen T; Sihvo S; Elovainio M; Tiihonen J; Lonnqvist J; Keskimaki I
Journal article: NEUROIMAGE. 2009;47:s183
Abnormal Cortical Morphology in Offenders with Psychopathy
Boccardi M; Frisoni G; Najt P; Pievani M; Ganzola R; Rossi R; Laakso M; Aronen H; Vaurio O; Perez J; Repo-Tiihonen E; Thompson P; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2009;168(1):18-25
Recidivistic offending and mortality in alcoholic violent offenders: A prospective follow-up study
Tikkanen R; Holi M; Lindberg N; Tiihonen J; Virkkunen M
Article: PSYCHIATRY RESEARCH. 2009;168(1):26-31
Low non-oxidative glucose metabolism and violent offending: An 8-year prospective follow-up study
Virkkunen M; Rissanen A; Franssila-Kallunki A; Tiihonen J
Article: JOURNAL OF ABNORMAL PSYCHOLOGY. 2009;118(2):418-423
Premorbid Personality Factors in Schizophrenia and Bipolar Disorder: Results From a Large Cohort Study of Male Conscripts
Lonnqvist J-E; Verkasalo M; Haukka J; Nyman K; Tiihonen J; Laaksonen I; Leskinen J; Lonnqvist J; Henriksson M
Article: SCHIZOPHRENIA RESEARCH. 2009;109(1-3):10-14
The efficacy of lamotrigine in clozapine-resistant schizophrenia: A systematic review and meta-analysis
Tiihonen J; Wahlbeck K; Kiviniemi V
Article: SCHIZOPHRENIA RESEARCH. 2009;108(1-3):245-251
Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia: A double-blind, randomized, placebo-controlled trial
Joffe G; Terevnikov V; Joffe M; Stenberg J-H; Burkin M; Tiihonen J
Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2009;33(3):428-434
Effects of MAOA-Genotype, Alcohol Consumption, and Aging on Violent Behavior
Tikkanen R; Sjoberg RL; Ducci F; Goldman D; Holi M; Tiihonen J; Virkkunen M
Article: ALCOHOL AND ALCOHOLISM. 2009;44(1):2-7
5-HT_1A Receptors in the Frontal Cortical Brain Areas in Cloninger Type 1 and 2 Alcoholics Measured by Whole-Hemisphere Autoradiography
Storvik M; Hakkinen M; Tupala E; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2008;163(3):201-212
Brain anatomy of persistent violent offenders:: More rather than less
Tiihonen J; Rossi R; Laakso MP; Hodgins S; Testa C; Perez J; Repo-Tiihonen E; Vaurio O; Soininen H; Aronen HJ; Kononen M; Thompson PA; Frisoni GB
Article: NEUROSCIENCE LETTERS. 2008;441(3):291-295
Midbrain serotonin and striatum dopamine transporter binding in double depression: A one-year follow-up study
Lehto SM; Tolmunen T; Kuikka J; Valkonen-Korhonen M; Joensuu M; Saarinen PI; Vanninen R; Ahola P; Tiihonen J; Lehtonen J
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2008;28(4):270-276
Association of serotonin transporter promoter regulatory region polymorphism and cerebral activity to visual presentation of food
Kaurijoki S; Kuikka JT; Niskanen E; Carlson S; Pietilainen KH; Pesonen U; Kaprio JM; Rissanen A; Tiihonen J; Karhunen L
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2008;17(7):686-696
Association between medication and risk of suicide, attempted suicide and death in nationwide cohort of suicidal patients with schizophrenia
Haukka J; Tiihonen J; Haerkaenen T; Loennqvist J
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2008;62(7):508-515
Autoradiographic characterization of α_2C-adrenoceptors in the human striatum
Fagerholm V; Rokka J; Nyman L; Sallinen J; Tiihonen J; Tupala E; Haaparanta M; Hietala J
Article: PSYCHIATRY AND CLINICAL NEUROSCIENCES. 2008;62(3):345-348
Temporal cortex dopamine D_2/3 receptor binding in major depression
Lehto SM; Kuikka J; Tolmunen T; Hintikka J; Viinamaki H; Vanninen R; Haatainen K; Koivumaa-Honkanen H; Honkalampi K; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2008;163(1):70-75
Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [³H]dihydrotetrabenazine and human whole hemisphere autoradiography
Tupala E; Hakkinen M; Storvik M; Tiihonen J
Journal article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 2008;19(1):33-51
Characterization of metabolic syndrome among forensic psychiatric inpatients
Ojala K; Niskanen L; Tiihonen J; Paavola P; Putkonen A; Repo-Tiihonen E
Article: PSYCHIATRY RESEARCH. 2008;162(1):1-9
Cortical dopamine D₁ receptors in type 1 and type 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E; Tiihonen J
Article: SUBSTANCE ABUSE. 2008;29(3):31-49
Pharmacotherapy of Methamphetamine Addiction: An Update
Elkashef A; Vocci F; Hanson G; White J; Wickes W; Tiihonen J
Article: JOURNAL OF PSYCHOPHARMACOLOGY. 2008;22(1):33-38
Statins are effective in treating dyslipidemia among psychiatric patients using second-generation antipsychotic agents
Ojala K; Repo-Tiihonen E; Tiihonen J; Niskanen L
Article: ALCOHOL AND ALCOHOLISM. 2008;43(1):25-30
Correlation between the SERT binding densities in hypothalamus and amygdala in Cloninger type 1 and 2 alcoholics
Storvik M; Haukijarvi T; Tupala E; Tiihonen J
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2007;42(10):845-850
Body size and violent offending among males in the Northern Finland 1966 birth cohort
Ikaheimo P; Rasanen P; Hakko H; Hartikainen A-L; Laitinen J; Hodgins S; Tiihonen J
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2007;61(8):629-636
Amygdala serotonin transporters in alcoholics measured by whole hemisphere autoradiography
Storvik M; Tiihonen J; Haukijarvi T; Tupala E
Article: PSYCHIATRY RESEARCH. 2007;150(3):287-295
Energy substrate: metabolism among habitually violent alcoholic offenders having antisocial personality disorder
Virkkunen M; Rissanen A; Naukkarinen H; Franssila-Kallunki A; Linnoila M; Tiihonen J
Journal article: INTERNATIONAL JOURNAL OF FORENSIC MENTAL HEALTH. 2007;6(1):63-75
A Comparison of General Adult and Forensic Patients with Schizophrenia Living in the Community
Hodgins S; Müller-Isberner R; Freese R; Tiihonen J; Repo-Tiihonen E; Eronen M; Eaves D; Hart S; Webster C; Levander S; Tuninger E; Ross D; Vartiainen H; Kronstrand R
Article: SCHIZOPHRENIA RESEARCH. 2007;91(1-3):97-102
Violent persons with schizophrenia and comorbid disorders:: A functional magnetic resonance imaging study
Joyal CC; Putkonen A; Mancini-Marie A; Hodgins S; Kononen M; Boulay L; Pihlajamaki M; Soininen H; Stip E; Tiihonen J; Aronen HJ
Article: PSYCHIATRY RESEARCH. 2007;154(2):125-131
Reduced midbrain serotonin transporter availability in drug-naive patients with depression measured by SERT-specific [¹²³I] nor-β-CIT SPECT imaging
Joensuu M; Tolmunen T; Saarinen PI; Tiihonen J; Kuikka J; Ahola P; Vanninen R; Lehtonen J
Article: SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY. 2007;42(2):94-99
Transmission of violent offending and crime across three generations
Putkonen A; Ryynanen O-P; Eronen M; Tiihonen J
Article: CRIMINAL JUSTICE AND BEHAVIOR. 2007;34(2):211-228
A multisite study of community treatment programs for mentally ill offenders with major mental disorders -: Design, measures, and the forensic sample
Hodgins S; Tengstrom A; Eriksson A; Osterman R; Kronstrand R; Eaves D; Hart S; Webster C; Ross D; Levin A; Levander S; Tuninger E; Mueller-Isberner R; Freese R; Tiihonen J; Kotilainen I; Repo-Tiihonen E; Vaananen K; Eronen M; Vokkolainen A; Vartiainen H
Article: PLOS ONE. 2007;2(1):e181
Functional COMT Val158Met Polymorphism, Risk of Acute Coronary Events and Serum Homocysteine: The Kuopio Ischaemic Heart Disease Risk Factor Study
Voutilainen S; Tuomainen T-P; Korhonen M; Mursu J; Virtanen JK; Happonen P; Alfthan G; Erlund I; North KE; Mosher MJ; Kauhanen J; Tiihonen J; Kaplan GA; Salonen JT
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2007;164(1):160-162
A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence
Tiihonen J; Kuoppasalmi K; Fohr J; Tuomola P; Kuikanmaki O; Vorma H; Sokero P; Haukka J; Meririnne E
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2006;16(8):552-560
Visualization of the cortical dopamine transporter in type 1 and 2 alcoholics with human whole hemisphere autoradiography
Tupala E; Halonen P; Tiihonen J
Article: ARCHIVES OF GENERAL PSYCHIATRY. 2006;63(12):1358-1367
Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort
Tiihonen J; Lonnqvist J; Wahlbeck K; Klaukka T; Tanskanen A; Haukka J
Article: ALCOHOL. 2006;40(3):177-184
Nucleus accumbens serotonin transporters in alcoholics measured by whole-hemisphere autoradiography
Storvik M; Tiihonen J; Haukijarvi T; Tupala E
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2006;256(6):382-387
Midbrain dopamine D_2/3 receptor binding in schizophrenia
Tuppurainen H; Kuikka JT; Laakso MP; Viinamaki H; Husso M; Tiihonen J
Article: BMJ-BRITISH MEDICAL JOURNAL. 2006;333(7561):224-227
Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder:: observational follow-up study
Tiihonen J; Wahlbeck K; Lonnqvist J; Klaukka T; Ioannidis JPA; Volavka J; Haukka J
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2006;59(3):144-151
Lower serotonin transporter binding in caudate in alcoholics
Storvik M; Tiihonen J; Haukijärvi T; Tupala E
Article: SCHIZOPHRENIA RESEARCH. 2005;78(2-3):323-335
The consequences of Conduct Disorder for males who develop schizophrenia: Associations with criminality, aggressive behavior, substance use, and psychiatric services
Hodgins S; Tiihonen J; Ross D
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2005;162(10):1904-1910
Premorbid intellectual functioning in bipolar disorder and schizophrenia:: Results from a cohort study of male conscripts
Tiihonen J; Haukka J; Henriksson M; Cannon M; Kieseppä T; Laaksonen I; Sinivuo J; Lönnqvist J
Article: HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL. 2005;20(7):467-472
Seasonal variations in [³H]citalopram platelet binding between healthy controls and violent offenders in Finland
Callaway J; Storvik M; Halonen P; Hakko H; Räsänen P; Tiihonen J
Article: PSYCHOPHARMACOLOGY. 2005;181(2):412-413
Visualisation of the cortical dopamine D₃ receptors in alcoholics and controls with human whole-hemisphere autoradiography
Tupala E; Hall H; Tiihonen J
Article: JOURNAL OF CLINICAL PSYCHIATRY. 2005;66(8):1012-1015
Topiramate add-on in treatment-resistant schizophrenia:: A randomized, double-blind, placebo-controlled, crossover trial
Tiihonen J; Halonen P; Wahlbeck K; Repo-Tiihonen E; Hyvärinen S; Eronen M; Putkonen H; Takala P; Mehtonen IP; Puck M; Oksanen J; Koskelainen P; Joffe G; Aer J; Hallikainen T; Ryynänen IP; Tupala E
Article: BRAIN RESEARCH. 2005;1031(1):20-29
Striatal dopamine D₁ receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2005;72(2-3):225-234
Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis
Tuominen HJ; Tiihonen J; Wahlbeck K
Article: NEUROPSYCHOBIOLOGY. 2005;51(4):173-176
Effects of venlafaxine treatment on clozapine plasma levels in schizophrenic patients
Repo-Tiihonen E; Eloranta A; Hallikainen T; Tiihonen J
Article: AMERICAN JOURNAL OF PSYCHOTHERAPY. 2005;59(1):61-73
An outcome of psychodynamic psychotherapy: a case study of the change in serotonin transporter binding and the activation of the dream screen.
Saarinen PI; Lehtonen J; Joensuu M; Tolmunen T; Ahola P; Vanninen R; Kuikka J; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2004;132(2):173-181
Reduced brain serotonin transporter binding in patients with panic disorder
Maron E; Kuikka JT; Shlik J; Vasar V; Vanninen E; Tiihonen J
Article: JOURNAL OF NEURAL TRANSMISSION. 2004;111(12):1605-1610
A controlled study of tryptophan and cortisol in violent offenders
Soderstrom H; Blennow K; Forsman A; Liesivuori J; Pennanen S; Tiihonen J
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2004;254(6):392-396
SPECT imaging of serotonin transporter binding in patients with generalized anxiety disorder
Maron E; Kuikka JT; Ulst K; Tiihonen J; Vasar V; Shlik J
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2004;54(3):129-137
Cortical dopamine D₂ receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E; Hall H; Halonen P; Tiihonen J
Article: BMC PSYCHIATRY. 2004;4:27
Elevated midbrain serotonin transporter availability in mixed mania: a case report
Tolmunen T; Joensuu M; Saarinen PI; Mussalo H; Ahola P; Vanninen R; Kuikka J; Tiihonen J; Lehtonen J
Article: NEUROSCIENCE LETTERS. 2004;367(3):313-316
Distribution of 5-HT₇ receptors in the human brain:: a preliminary autoradiographic study using [³H]SB-269970
Varnäs K; Thomas DR; Tupala E; Tiihonen J; Hall H
Article: PSYCHIATRY RESEARCH. 2004;131(2):115-124
MRI volumetry of the vermis and the cerebellar hemispheres in men with schizophrenia
Joyal CC; Pennanen C; Tiihonen E; Laakso MP; Tiihonen J; Aronen HJ
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2004;254(3):152-155
¹²³I-β-CIT binding and recovery from depression -: A six-month follow-up study
Laasonen-Balk T; Viinamäki H; Kuikka JT; Husso-Saastamoinen M; Lehtonen J; Tiihonen J
Article: BIOLOGICAL PSYCHIATRY. 2004;55(8):871-873
Brain serotonin 1A receptor binding in bulimia nervosa
Tiihonen J; Keski-Rahkonen A; Löppönen M; Muhonen M; Kajander J; Allonen T; Någren K; Hietala J; Rissanen A
Article: PSYCHOLOGICAL MEDICINE. 2004;34(3):433-442
Characteristics and circumstances of homicidal acts committed by offenders with schizophrenia
Joyal CC; Putkonen A; Paavola P; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 2004;30(1):59-72
Comorbid personality disorders and substance use disorders of mentally ill homicide offenders: A structured clinical study on dual and triple diagnoses
Putkonen A; Kotilainen I; Joyal CC; Tiihonen J
Journal article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2004;120(17):2033-2035
[Omega-3 fatty acids, new treatment for depression].
Tanskanen A; Tiihonen J
Journal article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2004;120(10):1191-1192
[Treatment for drug addiction].
Tiihonen J
Journal article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2004;120(1):85-86
[Lamotrigine in clozapine treatment-resistant schizophrenia].
Tiihonen J; Hallikainen T; Ryynänen O-P; Repo-Tiihonen E; Kotilainen I; Eronen M; Toivonen P; Wahlbeck K; Putkonen A
Article: BIOLOGICAL PSYCHIATRY. 2003;54(11):1302-1304
The amygdala and schizophrenia:: A volumetric magnetic resonance imaging study in first-episode, neuroleptic-naive patients
Joyal CC; Laakso MP; Tiihonen J; Syvälahti E; Vilkman H; Laakso A; Alakare B; Räkköläinen V; Salokangas RKR; Hietala J
Article: BIOLOGICAL PSYCHIATRY. 2003;54(11):1241-1248
Lamotrigine in treatment-resistant schizophrenia:: A randomized placebo-controlled crossover trial
Tiihonen J; Hallikainen T; Ryynänen OP; Repo-Tiihonen E; Kotilainen I; Eronen M; Toivonen P; Wahlbeck K; Putkonen A
Article: HUMAN BRAIN MAPPING. 2003;20(2):91-102
Dopamine D₂ receptors and transporters in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E; Hall H; Bergström K; Mantere T; Räsänen P; Särkioja T; Tiihonen J
Article: PSYCHOPHARMACOLOGY. 2003;170(1):89-93
Treatment improves serotonin transporter binding and reduces binge eating
Tammela LI; Rissanen A; Kuikka JT; Karhunen LJ; Bergström KA; Repo-Tiihonen E; Naukkarinen H; Vanninen E; Tiihonen J; Uusitupa M
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2003;108(3):244-246
Total plasma L-tryptophan, free L-tryptophan and competing amino acid levels in a homicidal male adolescent with conduct disorder
Virkkunen M; Ebeling H; Moilanen I; Tani P; Pennanen S; Liesivuori J; Tiihonen J
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 2003;48(4):205-211
Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics
Tupala E; Hall H; Bergström K; Mantere T; Räsänen P; Särkioja T; Hiltunen J; Tiihonen J
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2003;119A(2):152-155
Ethanol consumption and DRD2 gene TaqI a polymorphism among socially drinking males
Hallikainen T; Hietala J; Kauhanen J; Pobjalainen T; Syvälahti E; Salonen JT; Tiihonen J
Article: MOLECULAR PSYCHIATRY. 2003;8(4):453-455
Extrastriatal dopamine D_2/3 receptor density and distribution in drug-naive schizophrenic patients
Tuppurainen H; Kuikka J; Viinamäki H; Husso-Saastamoinen M; Bergström K; Tiihonen J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2002;71(1-3):51-59
Seasonal variation in specific methods of suicide:: a national register study of 20,234 Finnish people
Räsänen P; Hakko H; Jokelainen J; Tiihonen J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2002;70(2):197-203
Is occupation relevant in suicide?
Koskinen O; Pukkila K; Hakko H; Tiihonen J; Väisänen E; Särkioja T; Räsänen P
Article: PSYCHIATRY RESEARCH. 2002;114(2):95-102
Prefrontal volumes in habitually violent subjects with antisocial personality disorder and type 2 alcoholism
Laakso MP; Gunning-Dixon F; Vaurio O; Repo-Tiihonen E; Soininen H; Tiihonen J
Article: BIOLOGICAL PSYCHIATRY. 2002;51(12):1005-1007
A volumetric MRI study of the entorhinal cortex in first episode neuroleptic-naive schizophrenia
Joyal CC; Laakso MP; Tiihonen J; Syvälahti E; Vilkman H; Laakso A; Alakare B; Räkköläinen V; Salokangas RKR; Hietala J
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2002;159(4):599-606
Serotonin transporter distribution and density in the cerebral cortex of alcoholic and nonalcoholic comparison subjects:: A whole-hemisphere autoradiography study
Mantere T; Tupala E; Hall H; Särkioja T; Räsänen P; Bergström K; Callaway J; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2002;109(2):113-119
Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics
Saito T; Lachman HM; Diaz L; Hallikainen T; Kauhanen J; Salonen JT; Ryynänen OP; Karvonen MK; Syvälahti E; Pohjalainen T; Hietala J; Tiihonen J
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2002;252(1):8-11
Total serum cholesterol level, violent criminal offences, suicidal behavior, mortality and the appearance of conduct disorder in Finnish male criminal offenders with antisocial personality disorder
Repo-Tiihonen E; Halonen P; Tiihonen J; Virkkunen M
Article: SCHIZOPHRENIA BULLETIN. 2002;28(3):467-474
Impaired temporal lobe processing of preattentive auditory discrimination in schizophrenia
Pekkonen E; Katila H; Ahveninen J; Karhu J; Huotilainen M; Tiihonen J
Journal article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2002;118(6):553-555
[Personality disorders and brain imaging].
Tiihonen J
Journal article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 2002;13(3):555-568
Serum lipid levels and violence among Finnish male forensic psychiatric patients
Paavola P; Repo-Tiihonen E; Tiihonen J
Journal article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 2002;13(1):157-165
Seclusion treatment measures and serum cholesterol levels among Finnish male forensic psychiatric patients
Repo-Tiihonen E; Paavola P; Halonen P; Tiihonen J
Article: JOURNAL OF ADDICTIVE DISEASES. 2001;20(4):91-96
Dopamine transporter density and novelty seeking among alcoholics
Laine TPJ; Ahonen A; Räsänen P; Tiihonen J
Journal article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 2001;12(3):677-683
Mortality of antisocial male criminals
Repo-Tiihonen E; Virkkunen M; Tiihonen J
Article: PSYCHOPHARMACOLOGY. 2001;157(4):395-400
Free L-tryptophan plasma levels in antisocial violent offenders
Tiihonen J; Virkkunen M; Räsänen P; Pennanen S; Sainio EL; Callaway J; Halonen P; Liesivuori J
Article: JOURNAL OF AFFECTIVE DISORDERS. 2001;66(1):47-58
SPECT and neuropsychological performance in severe depression treated with ECT
Mervaala E; Könönen M; Föhr J; Husso-Saastamoinen M; Valkonen-Korhonen M; Kuikka JT; Viinamäki H; Tammi AK; Tiihonen J; Partanen J; Lehtonen J
Journal article: JOURNAL OF THREAT ASSESSMENT. 2001;1(4):41-51
Recidivism Among Serious Violent Crime Offenders in Finland
Paanila J; Hakola P; Tiihonen J
Article: ALCOHOL AND ALCOHOLISM. 2001;36(4):323-328
Altered frontal lobe function suggested by source analysis of event-related potentials in impulsive violent alcoholics
Tarkka IM; Karhu J; Kuikka J; Pääkkönen A; Bergström K; Partanen J; Tiihonen J
Article: NEUROIMAGE. 2001;14(1):87-94
Measurement of the striatal dopamine transporter density and heterogeneity in type 1 alcoholics using human whole hemisphere autoradiography
Tupala E; Kuikka JT; Hall H; Bergström K; Särkioja T; Räsänen P; Mantere T; Hiltunen J; Vepsäläinen J; Tiihonen J
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2001;28(7):911-913
Effects of ageing on serotonin transporters in healthy females
Kuikka JT; Tammela L; Bergström KA; Karhunen L; Uusitupa M; Tiihonen J
Article: SCHIZOPHRENIA RESEARCH. 2001;50(1-2):3-7
A morphometric MRI study of the hippocampus in first-episode, neuroleptic-naive schizophrenia
Laakso MP; Tiihonen J; Syvälahti E; Vilkman H; Laakso A; Alakare B; Räkköläinen V; Salokangas RKR; Koivisto E; Hietala J
Article: PSYCHOPHARMACOLOGY. 2001;155(3):310-314
Reduced serotonin transporter binding in binge eating women
Kuikka JT; Tammela L; Karhunen L; Rissanen A; Bergström KA; Naukkarinen H; Vanninen E; Karhu J; Lappalainen R; Repo-Tiihonen E; Tiihonen J; Uusitupa M
Article: ALCOHOL AND ALCOHOLISM. 2001;36(3):262-265
The A1 allele of the D₂ dopamine receptor gene is associated with high dopamine transporter density in detoxified alcoholics
Laine TPJ; Ahonen A; Räsänen P; Pohjalainen T; Tiihonen J; Hietala J
Article: MOLECULAR PSYCHIATRY. 2001;6(3):261-267
Dopamine D₂/D₃-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics
Tupala E; Hall H; Bergström K; Särkioja T; Räsänen P; Mantere T; Callaway J; Hiltunen J; Tiihonen J
Article: BRAIN RESEARCH. 2001;86(1-2):168-178
Characterization of γ-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions
Sinkkonen ST; Uusi-Oukari M; Tupala E; Särkioja T; Tiihonen J; Panula P; Lüddens H; Korpi ER
Article: BEHAVIOURAL BRAIN RESEARCH. 2001;118(2):187-193
Psychopathy and the posterior hippocampus
Laakso MP; Vaurio O; Koivisto E; Savolainen L; Eronen M; Aronen HJ; Hakola P; Repo E; Soinien H; Tiihonen J
Journal article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 2001;12(3):677-683
Mortality of antisocial male criminals
Repo-Tiihonen E; Virkkunen M; Tiihonen J
Article: JOURNAL OF NEUROSCIENCE METHODS. 2000;104(1):55-63
In vivo voltammetry with removable carbon fibre electrodes in freely-moving mice: dopamine release during intracranial self-stimulation
Yavich L; Tiihonen J
Article: NEUROSCIENCE LETTERS. 2000;293(1):41-44
Patterns of dopamine overflow in mouse nucleus accumbens during intracranial self-stimulation
Yavich L; Tiihonen J
Article: NEUROSCIENCE LETTERS. 2000;292(1):57-59
Specific binding and laterality of human extrastriatal dopamine D₂/D₃ receptors in late onset type 1 alcoholic patients
Kuikka JT; Repo E; Bergström KA; Tupala E; Tiihonen J
Article: PSYCHIATRIC GENETICS. 2000;10(3):117-124
Suicidal behavior in patients with schizophrenia is related to COMT polymorphism
Nolan KA; Volavka J; Czobor P; Cseh A; Lachman H; Saito T; Tiihonen J; Putkonen A; Hallikainen T; Kotilainen I; Räsänen P; Isohanni M; Järvelin MR; Karvonen MK
Article: INTERNATIONAL JOURNAL OF LAW AND PSYCHIATRY. 2000;23(5-6):541-546
Forensic psychiatric organization in Finland
Eronen M; Repo E; Vartiainen H; Tiihonen J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2000;401(3):365-373
Ethanol modulates evoked dopamine release in mouse nucleus accumbens: dependence on social stress and dose
Yavich L; Tiihonen J
Article: PSYCHIATRY RESEARCH. 2000;99(1):29-42
Regional cerebral blood flow during exposure to food in obese binge eating women
Karhunen LJ; Vanninen EJ; Kuikka JT; Lappalainen RI; Tiihonen J; Uusitupa MIJ
Article: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2000;96(3):348-352
Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early-onset alcoholism associated with severe antisocial behavior
Hallikainen T; Lachman H; Saito T; Volavka J; Kauhanen J; Salonen JT; Ryynänen OP; Koulu M; Karvonen MK; Pohjalainen T; Syvälahti E; Hietala J; Tiihonen J
Article: BEHAVIOURAL BRAIN RESEARCH. 2000;109(2):177-186
A volumetric MRI study of the hippocampus in type 1 and 2 alcoholism
Laakso MP; Vaurio O; Savolainen L; Repo E; Soininen H; Aronen HJ; Tiihonen J
Article: JOURNAL OF FORENSIC SCIENCES. 2000;45(2):390-391
Aging and homicide rates
Paanila J; Eronen M; Hakola P; Tiihonen J
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2000;27(2):206-208
Metabolism of [¹²³I]epidepride may affect brain dopamine D₂ receptor imaging with single-photon emission tomography
Bergström KA; Yu MX; Kuikka JT; Åkerman KK; Hiltunen J; Lehtonen J; Halldin C; Tiihonen J
Article: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2000;24(2):135-139
Association between the functional polymorphism of catechol-O-methyltransferase gene and alcohol consumption among social drinkers
Kauhanen J; Hallikainen T; Tuomainen TP; Koulu M; Karvonen MK; Salonen JT; Tiihonen J
Article: LANCET. 2000;355(9201):380
Dopamine-transporter density in nucleus accumbens of type-1 alcoholics
Tupala E; Hall H; Särkioja T; Räsänen P; Tiihonen J
Article: PSYCHOLOGICAL MEDICINE. 2000;30(1):117-125
Quantitative MRI of the hippocampus and amygdala in severe depression
Mervaala E; Föhr J; Könönen M; Valkonen-Korhonen M; Vainio P; Partanen K; Partanen J; Tiihonen J; Viinamäki H; Karjalainen AK; Lehtonen J
Journal article: NORDIC JOURNAL OF PSYCHIATRY. 2000;54(5):361-363
Benzodiazepine receptor density in major depression
Laasonen-Balk T; Viinamäki H; Kuikka J; Lehtonen J; Husso-Saastamoinen M; Mervaala E; Partanen J; Tiihonen J
Article: PSYCHOPHARMACOLOGY. 1999;147(3):314-318
Dopamine transporter and D₂-receptor density in late-onset alcoholism
Repo E; Kuikka JT; Bergström KA; Karhu J; Hiltunen J; Tiihonen J
Journal article: FORENSIC SCIENCE INTERNATIONAL. 1999;105(3):195
Mortality among habitually violent offenders (vol 100, pg 187, 1999)
Paanila J; Hakola P; Tiihonen J
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1999;26(11):1486-1488
Iodine-123 labelled PE21 for dopamine transporter imaging:: influence of age in healthy subjects
Kuikka JT; Tupala E; Bergström KA; Hiltunen J; Tiihonen J
Article: JOURNAL OF AFFECTIVE DISORDERS. 1999;55(1):67-71
Outcome of different types of long-term antidepressant treatments:: a 3-year follow-up study of 14 182 patients
Räsänen P; Hakko H; Jokelainen J; Tiihonen J
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 1999;19(4):297-302
Pindolol and major affective disorders:: A three-year follow-up study of 30,485 patients
Räsänen P; Hakko H; Tiihonen J
Article: MOLECULAR PSYCHIATRY. 1999;4(4):385-388
Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior
Hallikainen T; Saito T; Lachman HM; Volavka J; Pohjalainen T; Ryynänen OP; Kauhanen J; Syvälahti E; Hietala J; Tiihonen J
Article: PSYCHIATRY RESEARCH. 1999;90(3):153-157
Dopamine transporter availability and depressive symptoms during alcohol withdrawal
Laine TPJ; Ahonen A; Räsänen P; Tiihonen J
Article: PSYCHOPHARMACOLOGY. 1999;144(3):282-285
Striatal dopamine transporter density in major depression
Laasonen-Balk T; Kuikka J; Viinamäki H; Husso-Saastamoinen M; Lehtonen J; Tiihonen J
Article: AMERICAN JOURNAL OF PSYCHIATRY. 1999;156(6):857-862
Maternal smoking during pregnancy and risk of criminal behavior among adult male offspring in the northern Finland 1966 birth cohort
Räsänen P; Hakko H; Isohanni M; Hodgins S; Järvelin MR; Tiihonen J
Article: MOLECULAR PSYCHIATRY. 1999;4(3):286-289
Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism
Tiihonen J; Hallikainen T; Lachman H; Saito T; Volavka J; Kauhanen J; Salonen JT; Ryynänen OP; Koulu M; Karvonen MK; Pohjalainen T; Syvälahti E; Hietala J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 1999;99(5):348-352
Serum testosterone levels, mental disorders and criminal behaviour
Räsänen P; Hakko H; Visuri S; Paanila J; Kapanen P; Suomela T; Tiihonen J
Journal article: ACTA PSYCHIATRICA SCANDINAVICA. 1999;99(4):309-310
Cosinor modelling of suicides in Finland -: Reply
Hakko H; Räsänen P; Tiihonen J
Article: FORENSIC SCIENCE INTERNATIONAL. 1999;100(3):187-191
Mortality among habitually violent offenders
Paanila J; Hakola P; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 1999;25(3):601-607
Altered parallel auditory processing in schizophrenia patients
Pekkonen E; Huotilainen M; Katila H; Karhu J; Näätänen R; Tiihonen J
Article: SOCIAL SCIENCE & MEDICINE. 1998;47(11):1695-1698
Increasing homicide rate in Finland accompanied by decreasing seasonality over the period 1957-95
Hakko H; Räsänen P; Tiihonen J
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 1998;8:s171
Chronic pindolol treatment and major affective disorders
Tiihonen J; Räsänen P; Hakko H
Article: NEUROSCIENCE LETTERS. 1998;253(3):195-197
Abnormal structure of human striatal dopamine re-uptake sites in habitually violent alcoholic offenders:: a fractal analysis
Kuikka JT; Tiihonen J; Bergström KA; Karhu J; Räsänen P; Eronen M
Article: PHYSIOLOGICAL MEASUREMENT. 1998;19(3):367-374
Imaging the structure of the striatum: a fractal approach to SPECT image interpretation
Kuikka JT; Yang J; Karhu J; Laitinen T; Tupala E; Hallikainen T; Tiihonen J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 1998;98(2):92-97
Seasonal variation in suicide occurrence in Finland
Hakko H; Rasanen P; Tiihonen J
Article: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 1998;29(4):413-415
Fentanyl decreases β-CIT binding to the dopamine transporter
Bergström KA; Jolkkonen J; Kuikka JT; Åkerman KK; Viinamäki H; Airaksinen O; Länsimies E; Tiihonen J
Article: JOURNAL OF AFFECTIVE DISORDERS. 1998;50(1):49-54
Secular trends in the rates and seasonality of violent and nonviolent suicide occurrences in Finland during 1980-95
Hakko H; Räsänen P; Tiihonen J
Journal article: PATHOPHYSIOLOGY. 1998;5:183
Is there a role for leptin in the regulation of hunger in humans?
Karhunen L; Lappalainen R; Vanninen E; Kuikka JT; Tiihonen J; Uusitupa M
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1998;25(5):531-534
Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging
Kuikka JT; Baulieu JL; Hiltunen J; Halldin C; Bergström KA; Farde L; Emond P; Chalon S; Yu MX; Nikula T; Laitinen T; Karhu J; Tupala E; Hallikainen T; Kolehmainen V; Mauclaire L; Maziere B; Tiihonen J; Guilloteau D
Article: SCHIZOPHRENIA RESEARCH. 1998;30(3):209-219
Reversal of cerebral asymmetry in schizophrenia measured with magnetoencephalography
Tiihonen J; Katila H; Pekkonen E; Jääskeläinen IP; Huotilainen M; Aronen HJ; Ilmoniemi RJ; Räsänen P; Virtanen J; Salli E; Karhu J
Article: HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL. 1998;13(3):177-182
The metabolism of iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)-7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine (NNC13-8241) measured in human plasma is only minor
Akerman KK; Bergstrom KA; Halldin C; Lotjonen S; Yu MX; Nikula T; Hiltunen J; Foged C; Kuikka JT; Tiihonen J
Article: MOLECULAR PSYCHIATRY. 1998;3(2):156-161
Striatal presynaptic dopamine function in type 1 alcoholics measured with positron emission tomography
Tiihonen J; Vilkman H; Rasanen P; Ryynanen OP; Hakko H; Bergman J; Hamalainen T; Laakso A; Haaparanta-Solin M; Solin O; Kuoppamaki M; Syvalahti E; Hietala J
Article: JOURNAL OF AFFECTIVE DISORDERS. 1998;48(1):63-68
The incidence and onset-age of hospitalized bipolar affective disorder in Finland
Räsänen P; Tiihonen J; Hakko H
Article: SCHIZOPHRENIA BULLETIN. 1998;24(3):437-441
Schizophrenia, alcohol abuse, and violent behavior:: A 26-year followup study of an unselected birth cohort
Räsänen P; Tiihonen J; Isohanni M; Rantakallio P; Lehtonen J; Moring J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 1998;97(1):5-9
Juvenile mortality, mental disturbances and criminality: a prospective study of the Northern Finland 1966 birth cohort
Rasanen P; Tiihonen J; Isohanni M; Moring J; Koiranen M
Journal article: EUROPEAN PSYCHIATRY. 1998;13(S4):133s
S1-2 Meg-based evidence of accelerated auditory processing in schizophrenia
Pekkonen E; Huotilainen M; Katila H; Karhu J; Näätänen R; Tiihonen J
Journal article: NORDIC JOURNAL OF PSYCHIATRY. 1998;52(1):39-44
Change in monoamine transporter density related to clinical recovery: A case-control study
Viinamaki H; Kuikka J; Tiihonen J; Lehtonen J
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1997;25(1):19-23
Iodine-123 labeled nor-β-CIT as a potential tracer for serotonin transporter imaging in the human brain with single-photon emission tomography
Hiltunen J; Åkerman KK; Kuikka JT; Bergström KA; Halldin C; Nikula T; Räsänen P; Tiihonen J; Vauhkonen M; Karhu J; Kupila J; Länsimies E; Farde L
Article: AMERICAN JOURNAL OF PSYCHIATRY. 1997;154(12):1711-1714
Seasonal variation in the occurrence of homicide in Finland
Tiihonen J; Rasanen P; Hakko H
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1997;24(10):1253-1260
Single-photon emission tomography imaging of monoamine transporters in impulsive violent behaviour
Tiihonen J; Kuikka JT; Bergstrom KA; Karhu J; Viinamaki H; Lehtonen J; Hallikainen T; Yang JW; Hakola P
Article: MOLECULAR PSYCHIATRY. 1997;2(6):463-471
Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis
Tiihonen J; Kuikka J; Rasanen P; Lepola U; Koponen H; Liuska A; Lehmusvaara A; Vainio P; Kononen M; Bergstrom K; Yu M; Kinnunen I; Akerman K; Karhu J
Journal article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1997;24(9):1085-1090
Fractal analysis of striatal dopamine re-uptake sites
Kuikka JT; Tiihonen J; Karhu J; Bergström KA; Räsänen P
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1997;24(9):1085-1090
Fractal analysis of striatal dopamine re-uptake sites
Kuikka JT; Tiihonen J; Karhu J; Bergstrom KA; Rasanen P
Journal article: BIOLOGICAL PSYCHIATRY. 1997;42(1):23s
14-9 Seasonal variation of homicide occurrence in Finland
Tiihonen J; Räsänen P; Hakko H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 1997;154(6):840-845
Specific major mental disorders and criminality: A 26-year prospective study of the 1966 Northern Finland birth cohort
Tiihonen J; Isohanni M; Rasanen P; Koiranen M; Moring J
Journal article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1997;24(5):483-487
Striatal and extrastriatal imaging of dopamine D 2 receptors in the living human brain with [ 123 I]epidepride single-photon emission tomography
Kuikka JT; Åkerman KK; Hiltunen J; Bergström KA; Räsänen P; Vanninen E; Halldin C; Tiihonen J
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1997;24(5):483-487
Striatal and extrastriatal imaging of dopamine D-2 receptors in the living human brain with [I-123]epidepride single-photon emission tomography
Kuikka JT; Akerman KK; Hiltunen J; Bergstrom KA; Rasanen P; Vanninen E; Halldin C; Tiihonen J
Article: AMERICAN JOURNAL OF PSYCHIATRY. 1997;154(2):239-242
Dopamine reuptake site densities in patients with social phobia
Tiihonen J; Kuikka J; Bergstrom K; Lepola U; Koponen H; Leinonen E
Journal article: INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. 1997;1(3):179-188
Psychiatric disorders and violent behavior.
Eronen M; Tiihonen J; Hakola P
Article: HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL. 1996;11(6):483-490
Characterization of C-11 or I-123 labelled beta-CIT-FP and beta-CIT-FE metabolism measured in monkey and human plasma. Identification of two labelled metabolites with HPLC
Bergstrom KA; Halldin C; Lundkvist C; Swahn CG; Akerman KK; Kuikka JT; Hiltunen J; Tiihonen J; Lansimies E; Neumeyer JL; Farde L
Article: PSYCHOPHARMACOLOGY. 1996;126(4):277-280
Serotonergic modulation of striatal D-2 dopamine receptor binding in humans measured with positron emission tomography
Tiihonen J; Kuoppamaki M; Nagren K; Bergman J; Eronen E; Syvalahti E; Hietala J
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1996;23(7):798-803
Initial human studies with single-photon emission tomography using iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)-7-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine (NNC 13-8241)
Kuikka JT; Hiltunen J; Foged C; Bergstrom KA; Halldin C; Akerman K; Tiihonen J; Farde L
Article: ARCHIVES OF GENERAL PSYCHIATRY. 1996;53(6):497-501
Mental disorders and homicidal behavior in Finland
Eronen M; Hakola P; Tiihonen J
Article: FORENSIC SCIENCE INTERNATIONAL. 1996;79(2):123-129
Risk of homicidal behavior among discharged forensic psychiatric patients
Tiihonen J; Hakola P; Eronen M; Vartiainen H; Ryynanen OP
Article: PSYCHIATRIC SERVICES. 1996;47(4):403-406
Factors associated with homicide recidivism in a 13-year sample of homicide offenders in Finland
Eronen M; Hakola P; Tiihonen J
Article: SCHIZOPHRENIA BULLETIN. 1996;22(1):83-89
Schizophrenia and homicidal behavior
Eronen M; Tiihonen J; Hakola P
Article: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 1996;112(14):1281-1286
[Homicide behavior of females in Finland between years of 1980-1994].
Eronen M; Tiihonen J; Hakola P
Article: PHARMACOPSYCHIATRY. 1996;29(1):27-29
Citalopram in the treatment of alcoholism: A double-blind placebo-controlled study
Tiihonen J; Ryynanen OP; Kauhanen J; Hakola HPA; Salaspuro M
Article: JOURNAL OF FORENSIC PSYCHIATRY & PSYCHOLOGY. 1995;6(3):477-485
Quantitative risk assessment of homicidal behaviour
Tiihonen J
Journal article: AMERICAN JOURNAL OF PSYCHIATRY. 1995;152(11):1695-a-1696
Drs. Tiihonen and Kuikka Reply
TIIHONEN J; KUIKKA J
Journal article: CLINICAL NEUROPHYSIOLOGY. 1995;95(4):p96
ERPs in impulsive violent offenders
Karhu J; Partanen J; Tiihonen J; Kuika J; Pääkkönen A; Bergstrom K; Hakola P
Article: NATURE MEDICINE. 1995;1(7):654-657
ALTERED STRIATAL DOPAMINE REUPTAKE SITE DENSITIES IN HABITUALLY VIOLENT AND NON-VIOLENT ALCOHOLICS
TIIHONEN J; KUIKKA J; BERGSTROM K; HAKOLA P; KARHU J; RYYNANEN OP; FOHR J
Article: ACTA PSYCHIATRICA SCANDINAVICA. 1995;91(5):348-351
CITALOPRAM, A SELECTIVE SEROTONIN REUPTAKE INHIBITOR, IN THE TREATMENT OF AGGRESSION IN SCHIZOPHRENIA
VARTIAINEN H; TIIHONEN J; PUTKONEN A; KOPONEN H; VIRKKUNEN M; HAKOLA P; LEHTO H
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1995;22(4):346-350
IMAGING OF SEROTONIN AND DOPAMINE TRANSPORTERS IN THE LIVING HUMAN BRAIN
KUIKKA JT; TIIHONEN J; BERGSTROM KA; KARHU J; HARTIKAINEN P; VIINAMAKI H; LANSIMIES E; LEHTONEN J; HAKOLA P
Article: FORENSIC SCIENCE INTERNATIONAL. 1995;72(1):43-48
RISK OF HOMICIDAL BEHAVIOR AMONG PERSONS CONVICTED OF HOMICIDE
TIIHONEN J; HAKOLA P; NEVALAINEN A; ERONEN M
Article: PHARMACOPSYCHIATRY. 1995;28(1):26-28
CARBAMAZEPINE-INDUCED CHANGES IN PLASMA-LEVELS OF NEUROLEPTICS
TIIHONEN J; VARTIAINEN H; HAKOLA P
Journal article: AMERICAN JOURNAL OF PSYCHIATRY. 1994;151(10):1505-1508
ACUTE ETHANOL-INDUCED CHANGES IN CEREBRAL BLOOD-FLOW
TIIHONEN J; KUIKKA J; HAKOLA P; PAANILA J; AIRAKSINEN J; ERONEN M; HALLIKAINEN T
Journal article: NEUROSCIENCE LETTERS. 1994;170(2):241-243
INCREASE IN CEREBRAL BLOOD-FLOW OF RIGHT PREFRONTAL CORTEX IS MAN DURING ORGASM
TIIHONEN J; KUIKKA J; KUPILA J; PARTANEN K; VAINIO P; AIRAKSINEN J; ERONEN M; HALLIKAINEN T; PAANILA J; KINNUNEN I; HUTTUNEN J
Journal article: AMERICAN JOURNAL OF PSYCHIATRY. 1994;151(3):436-438
PSYCHIATRIC-DISORDERS AND HOMICIDE RECIDIVISM
TIIHONEN J; HAKOLA P
Journal article: ARCHIVES OF GENERAL PSYCHIATRY. 1993;50(11):917-918
CRIMINALITY ASSOCIATED WITH MENTAL-DISORDERS AND INTELLECTUAL DEFICIENCY
TIIHONEN J; ERONEN M; HAKOLA P
Journal article: DEMENTIA. 1993;4(2):109-112
LONG-TERM EFFECTS OF BILATERAL FRONTAL-LOBE LESIONS FROM NEUROPSYCHIATRIC AND NEURORADIOLOGICAL ASPECTS
HAKOLA HPA; PURANEN M; REPO L; TIIHONEN J
Journal article: LANCET. 1993;341(8840):307
ELTOPRAZINE FOR AGGRESSION IN SCHIZOPHRENIA AND MENTAL-RETARDATION
TIIHONEN J; HAKOLA P; PAANILA J; TURTIAINEN M
Journal article: ANNALS OF NEUROLOGY. 1992;32(1):106-109
MAGNETOENCEPHALOGRAPHIC LOCALIZATION OF EPILEPTIC CORTEX - IMPACT ON SURGICAL-TREATMENT
PAETAU R; KAJOLA M; KARHU J; NOUSIAINEN U; PARTANEN J; TIIHONEN J; VAPALAHTI M; HARI R
Journal article: INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY. 1992;12(3):281-288
FAST DECREMENT WITH STIMULUS REPETITION IN ERPS GENERATED BY NEURONAL SYSTEMS INVOLVING SOMATOSENSORY SI AND SII CORTICES - ELECTRIC AND MAGNETIC EVOKED-RESPONSE RECORDINGS IN HUMANS
KEKONI J; TIIHONEN J; HAMALAINEN H
Journal article: LANCET. 1992;339(8791):488
EOSINOPHILIA ASSOCIATED WITH CLOZAPINE
TIIHONEN J; PAANILA J
Journal article: AMERICAN JOURNAL OF PSYCHIATRY. 1992;149(2):255-257
MODIFIED ACTIVITY OF THE HUMAN AUDITORY-CORTEX DURING AUDITORY HALLUCINATIONS
TIIHONEN J; HARI R; NAUKKARINEN H; RIMON R; JOUSMAKI V; KAJOLA M
Journal article: ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. 1992;82(2):152-154
NEUROMAGNETIC MISMATCH FIELDS TO SINGLE AND PAIRED TONES
HARI R; RIF J; TIIHONEN J; SAMS M
Journal article: AMERICAN JOURNAL OF PSYCHIATRY. 1991;148(10):1406
EEG ABNORMALITIES ASSOCIATED WITH CLOZAPINE TREATMENT
TIIHONEN J; NOUSIAINEN U; HAKOLA P; LEINONEN E; TUUNAINEN A; MERVAALA E; PAANILA J
Journal article: NEUROSCIENCE LETTERS. 1991;129(2):303-305
MAGNETOENCEPHALOGRAPHIC 10-HZ RHYTHM FROM THE HUMAN AUDITORY-CORTEX
TIIHONEN J; HARI R; KAJOLA M; KARHU J; AHLFORS S; TISSARI S
Journal article: ANNALS OF NEUROLOGY. 1990;28(5):726
MAGNETOENCEPHALOGRAPHIC LOCALIZATION OF EPILEPTIC FOCI - REPLY
HARI R; TIIHONEN J
Journal article: ANNALS OF NEUROLOGY. 1990;27(3):283-290
LOCALIZATION OF EPILEPTIC FOCI USING A LARGE-AREA MAGNETOMETER AND FUNCTIONAL BRAIN ANATOMY
TIIHONEN J; HARI R; KAJOLA M; NOUSIAINEN U; VAPALAHTI M
Journal article: NEUROSCIENCE. 1990;37(1):245-249
SEPARATE FINGER REPRESENTATIONS AT THE HUMAN 2ND SOMATOSENSORY CORTEX
HARI R; HAMALAINEN H; HAMALAINEN M; KEKONI J; SAMS M; TIIHONEN J
Journal article: ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. 1989;74(4):290-296
EARLY DEFLECTIONS OF CEREBRAL MAGNETIC RESPONSES TO MEDIAN NERVE-STIMULATION
TIIHONEN J; HARI R; HAMALAINEN M
Journal article: ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. 1989;74(3):217-227
EVOKED-RESPONSES OF HUMAN AUDITORY-CORTEX MAY BE ENHANCED BY PRECEDING STIMULI
LOVELESS N; HARI R; HAMALAINEN M; TIIHONEN J
Journal article: ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. 1989;72(3):277-280
MULTICHANNEL DETECTION OF MAGNETIC COMPOUND ACTION FIELDS OF MEDIAN AND ULNAR NERVES
HARI R; HALLSTROM J; TIIHONEN J; JOUTSINIEMI SL
Journal article: NEUROSCIENCE. 1989;32(3):793-800
MAGNETIC MU RHYTHM IN MAN
TIIHONEN J; KAJOLA M; HARI R
Journal article: EXPERIMENTAL BRAIN RESEARCH. 1989;74(3):463-470
SELECTIVE LISTENING MODIFIES ACTIVITY OF THE HUMAN AUDITORY-CORTEX
HARI R; HAMALAINEN M; KAUKORANTA E; MAKELA J; JOUTSINIEMI SL; TIIHONEN J
Journal article: INTERNATIONAL JOURNAL OF AUDIOLOGY. 1989;28(1):37-48
INTERAURAL INTERACTION IN THE HUMAN AUDITORY-CORTEX
TIIHONEN J; HARI R; KAUKORANTA E; KAJOLA M
Journal article: HUMAN GENETICS. 1988;79(1):29-35
MOLECULAR CHARACTERIZATION OF A Y-15 TRANSLOCATION SEGREGATING IN A FAMILY
ALITALO T; TIIHONEN J; HAKOLA P; DELACHAPELLE A
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Antipsychotic Monotherapy vs Polytherapy for Pneumonia Risk
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The challenges of antipsychotic polypharmacy
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Medication use and sickness absence from work in bipolar disorder: a nationwide register-based study
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Neurobiological background of male sexual orientation
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Dopamine D2R and opioid MOR availability in autism spectrum disorder
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Treatment Strategies and Their Comparative Effectiveness in Relapse Prevention After the First Relapse in Persons with First-Episode Schizophrenia
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Astrocytes regulate neuronal network burst frequency through NMDA receptors species- and donor-specifically
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Kynurenic acid promotes activity-dependent synaptic pruning in schizophrenia
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The use of long-acting injectables in early-phase schizophrenia
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Antidepressant use and psychosis hospitalization in persons with schizophrenia
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Aberrant type 2 dopamine receptor availability in criminal psychopathy
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Letter: PSYCHOLOGICAL MEDICINE. 2023;53(8):3764-3765
Correspondence regarding De Girolamo et al., 2021 'A multinational case-control study comparing forensic and non-forensic patients with schizophrenia spectrum disorders: the EU-VIORMED project'
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Optimal Doses of Specific Antipsychotics for Relapse Prevention in a Nationwide Cohort of Patients with Schizophrenia (vol 48, pg 774, 2022)
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Neurobiological Basis of Male Sexual Orientation
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Genetic contribution to microglial activation in schizophrenia
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Functional characterization of six SLCO1B1 (OATP1B1) variants observed in Finnish individuals with a psychotic disorder
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β2-adrenoceptor agonists and risk of Parkinson's disease: Nested case-control study of people with asthma or chronic obstructive pulmonary disease
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Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;53:S355
Antidepressant use and risk of psychiatric rehospitalization in patients with schizophrenia
Puranen A; Koponen M; Lahteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;53:S499-S500
Dipyridamole and calcium channel blockers in the treatment of bipolar disorder - a nationwide cohort study
Lintunen J; Lahteenvuo M; Tiihonen J; Tanskanen A; Taipale H
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;53:S453-S454
Associations between antipsychotic use, substance use and relapse risks in patients with schizophrenia - real-world evidence from two national cohorts
Lahteenvuo M; Luykx J; Taipale H; Mittendorfer-Rutz E; Tanskanen A; Batalla A; Tiihonen J
Editorial comment: AMERICAN JOURNAL OF PSYCHIATRY. 2021;178(10):888-889
Clozapine, Long-Acting Injectables (and Polypharmacy?) Superior in US and International Registries
Leucht S; Tiihonen J
Preprint: BIORXIV. 2021
Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans
Sun L; Lukkarinen L; Karlsson H; Hirvonen J; Tiihonen J; Lauerma H; Scott S; Nummenmaa L
Preprint: BIORXIV. 2021
Aberrant motor contagion of emotions in psychopathy and high-functioning autism
Sun L; Lukkarinen L; Noppari T; Nazari-Farsani S; Putkinen V; Seppälä K; Hudson M; Tani P; Lindberg N; Karlsson HK; Hirvonen J; Salomaa M; M. NV; Lauerma H; Tiihonen J; Nummenmaa L
Editorial comment: LANCET PSYCHIATRY. 2021;8(7):555-557
Antipsychotic discontinuation: mind the patient and the real-world evidence
Luykx JJ; Tiihonen J
Review: DRUGS. 2021;81(11):1273-1284
Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations
Lahteenvuo M; Tiihonen J
Preprint: PREPRINTS.ORG. 2021
Reaction Time and Visual Memory in Connection to Alcohol Use in Persons with Bipolar Disorder
Mazumder AH; Barnett J; Isometsä ET; Lindberg N; Torniainen-Holm M; Lähteenvuo M; Lahdensuo K; Kerkelä M; Ahola-Olli A; Hietala J; Kampman O; Kieseppä T; Jukuri T; Häkkinen K; Cederlöf E; Haaki W; Kajanne R; Wegelius A; Männynsalo T; Niemi-Pynttäri J; Suokas K; Lönnqvist J; Tiihonen J; Paunio T; Vainio SJ; Palotie A; Niemelä S; Suvisaari J; Veijola J
Preprint: MEDRXIV. 2021
Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorder
Okhuijsen-Pfeifer C; van der Horst MZ; Bousman CA; Lin B; van Eijk KR; Ripke S; Ayhan Y; Babaoglu MO; Bak M; Alink W; van Beek H; Beld E; Bouhuis A; Edlinger M; Erdogan IM; Ertuğrul A; Yoca G; Everall IP; Görlitz T; investigators GRAOOP; Grootens KP; Gutwinski S; Hallikainen T; Jeger-Land E; de Koning M; Lähteenvuo M; Legge SE; Leucht S; Morgenroth C; Müderrisoğlu A; Narang A; Pantelis C; Pardiñas AF; Oviedo-Salcedo T; Schneider-Thoma J; Schreiter S; Repo-Tiihonen E; Tuppurainen H; Veereschild M; Veerman S; de Vos M; Wagner E; Cohen D; Bogers JPAM; Walters JTR; Yağcıoğlu AEA; Tiihonen J; Hasan A; Luykx JJ
Preprint: PREPRINTS.ORG. 2021
Reaction Time and Visual Memory in Connection to Alcohol Use in Schizophrenia and Schizoaffective Disorder
Mazumder AH; Barnett J; Lindberg N; Holm M; Lähteenvuo M; Lahdensuo K; Kerkelä M; Hietala J; Isometsä E; Kampman O; Kieseppä T; Jukuri T; Häkkinen K; Cederlöf E; Haaki W; Kajanne R; Wegelius A; Männynsalo T; Niemi-Pynttäri J; Suokas K; Lönnqvist J; Niemelä S; Tiihonen J; Paunio T; Tuulio-Henriksson A; Palotie A; Suvisaari J; Veijola J
Conference publication: EUROPEAN PSYCHIATRY. 2021;64:S237-S238
Morbidity and mortality in schizophrenia with comorbid substance use disorders in Finland and Sweden
Lahteenvuo M; Batalla A; Luykx J; Mittendorfer-Rutz E; Tanskanen A; Tiihonen J; Taipale H
Conference publication: EUROPEAN PSYCHIATRY. 2021;64:S108
Use of pharmacotherapies for treatment resistant depression in finland: A nationwide cohort study
Taipale H; Lahteenvuo M; Tanskanen A; Rannanpaa S; Tiihonen J
Conference publication: EUROPEAN PSYCHIATRY. 2021;64:S161
Effectiveness of antipsychotics in schizophrenia with comorbid substance use disorder
Lahteenvuo M; Luykx J; Taipale H; Mittendorfer-Rutz E; Tanskanen A; Batalla A; Tiihonen J
Review: HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL. 2021;36(2)
Medication management of antipsychotic treatment in schizophrenia-A narrative review
Isohanni M; Jaaskelainen E; Miller BJ; Hulkko A; Tiihonen J; Moeller H-J; Hartikainen S; Huhtaniska S; Lieslehto J
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Long-Term Continuity of Antipsychotic Treatment for Schizophrenia: A Nationwide Study
Rubio JM; Taipale H; Tanskanen A; Correll C; Kane JM; Tiihonen J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2021;46(SUPPL 1):21
Are LAI Antipsychotics Really Better Than Orals?
Weiser M; Kahn R; Weiser M; Tiihonen J; Kane J; Fleischhacker W; Davidson M; Perkins D; Sommer I; Marder S; Carpenter W
Editorial comment: PSYCHOLOGICAL MEDICINE. 2020;50(16):2653-2654
Commentary on Robert Whitaker's viewpoint
Tiihonen J; Taipale H; Correll CU
Letter: PSYCHOLOGICAL MEDICINE. 2020;50(16):2812-2813
Rejoinder to rejoinder to commentary
Tiihonen J; Taipale H; Correll CU
Corrigendum: MOLECULAR PSYCHIATRY. 2020;25(12):3455-3456
Neurobiological roots of psychopathy (vol 25, pg 3432, 2020)
Tiihonen J; Koskuvi M; Lahteenvuo M; Virtanen PLJ; Ojansuu I; Vaurio O; Gao Y; Hyotylainen I; Puttonen KA; Repo-Tiihonen E; Paunio T; Rautiainen M-R; Tyni S; Koistinaho J; Lehtonen S
Preprint: MEDRXIV. 2020
Implementation of CYP2D6 copy-number imputation panel and frequency of key pharmacogenetic variants in Finnish individuals with a psychotic disorder
Häkkinen K; Kiiski J; Lähteenvuo M; Jukuri T; Suokas K; Niemi-Pynttäri J; Kieseppä T; Männynsalo T; Wegelius A; Haaki W; Lahdensuo K; Kajanne R; Kaunisto M; Tuulio-Henriksson A; Kampman O; Hietala J; Veijola J; Lönnqvist J; Isometsä E; Paunio T; Suvisaari J; Kalso E; Niemi M; Tiihonen J; Daly M; Palotie A; Ahola-Olli A
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;40:S268
Effectiveness of pharmacotherapies for delusional disorder in a Swedish national cohort of 9076 patients
Lahteenvuo M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;40:S273
Comparative effectiveness of antipsychotics for risk of attempted or completed suicide among persons with schizophrenia
Taipale H; Lahteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;40:S454
Real-world effectiveness of mood stabilizer use in persons with schizophrenia
Puranen A; Koponen M; Lahteenvuo M; Tanskanen A; Tiihonen J; Taipale H
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;40:S108-S109
Molecular pathways underlying schizophrenia
Tiihonen J; Koskuvi M; Lahteenvuo M; Trontti K; Ojansuu I; Vaurio O; Cannon TD; Lonnqvist J; Therman S; Suvisaari J; Cheng L; Tanskanen A; Taipale H; Lehtonen S; Koistinaho J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;40:S236-S237
Neuronavigated and individualized alpha frequency transcranial magnetic stimulation in treatment-refractory schizophrenia
Tuppurainen H; Maatta S; Kononen M; Julkunen P; Hyvarinen S; Vaurio O; Joensuu M; Vanhanen M; Aho-Mustonen K; Repo-Tiihonen E; Mervaala E; Tiihonen J
Preprint: BIORXIV. 2020
Patient iPSC-astrocytes show transcriptional and functional dysregulation in schizophrenia
Koskuvi M; Lehtonen Š; Trontti K; Keuters M; Wu YC; Koivisto H; Ludwig A; Plotnikova L; Virtanen PLJ; Räsänen N; Kaipainen S; Hyötyläinen I; Dhungana H; Giniatullina R; Ojansuu I; Vaurio O; Cannon TD; Lönnqvist J; Therman S; Suvisaari J; Kaprio J; Lähteenvuo M; Tohka J; Giniatullin R; Rivera C; Hovatta I; Tanila H; Tiihonen J; Koistinaho J
Corrigendum: BEHAVIOURAL BRAIN RESEARCH. 2020;393:112721
Monoamine oxidase A genotype and methylation moderate the association of maltreatment and aggressive behaviour (vol 382, 112476, 2020)
Checknita D; Bendre M; Ekstrom TJ; Comasco E; Tiihonen J; Hodgins S; Nilsson KW
Preprint: BIORXIV. 2020
Molecular signaling pathways underlying schizophrenia
Tiihonen J; Koskuvi M; Lähteenvuo M; Trontti K; Ojansuu I; Vaurio O; Cannon T; Lönnqvist J; Therman S; Suvisaari J; Cheng L; Tanskanen A; Taipale H; Lehtonen Š; Koistinaho J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2020;45(SUPPL 1):103-104
Treatment Resistant Depression in Finland (TRIFI): A Nationwide Cohort Study
Lahteenvuo M; Taipale H; Tanskanen A; Rannanpaa S; Tiihonen J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2020;45(SUPPL 1):245-246
Molecular Pathways Underlying Schizophrenia
Tiihonen J; Koskuvi M; Lahteenvuo M; Trontti K; Ojansuu I; Vaurio O; Cannon T; Lonnqvist J; Therman S; Suvisaari J; Cheng L; Tanskanen A; Taipale H; Lehtonen S; Koistinaho J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2020;29:126-127
Real-world effectiveness of mood stabilizer use in persons with schizophrenia
Puranen A; Koponen M; Markku L; Tanskanen A; Tiihonen J; Taipale H
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2020;29:295
Incident antiepileptic use and risk of hip fracture among persons with Alzheimer's disease
Pisa F; Reinold J; Lavikainen P; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2020;29:112
Comparative effectiveness of antipsychotics for risk of attempted or completed suicide among persons with schizophrenia
Taipale H; Lahteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2020;29:243
Development of antipsychotic doses among persons with newly diagnosed schizophrenia - Ten years of follow-up
Tanskanen A; Koponen M; Lahteenvuo M; Tiihonen J; Taipale H
Conference publication: SCHIZOPHRENIA BULLETIN. 2020;46:S118-S119
COMPARATIVE EFFECTIVENESS OF ANTIPSYCHOTICS FOR RISK OF ATTEMPTED OR COMPLETED SUICIDE AMONG PERSONS WITH SCHIZOPHRENIA
Taipale H; Lahteenvuo M; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Conference publication: SCHIZOPHRENIA BULLETIN. 2020;46:S311-S312
EFFECTIVENESS OF PHARMACOLOGICAL THERAPIES FOR DELUSIONAL DISORDER
Lahteenvuo M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Preprint: SSRN ELECTRONIC JOURNAL. 2020
Psychosis Relapse During Long-Acting Injectable Antipsychotic Treatment: An Individual Participant Data Meta-Analysis of 19 Trials and 5,111 Individuals with Schizophrenia-Spectrum Disorders
Rubio JM; Schoretsanitis G; John M; Tiihonen J; Taipale H; Guinart D; Malhotra AK; Correll CU; Kane JM
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2020;28(SUPPL 1):683
Imputation of CYP2D6 copy-number variation and frequency of key pharmacogenetic variants in Finnish population
Hakkinen K; Lahteenvuo M; Jukuri T; Suokas K; Niemi-Pynttari J; Kieseppa T; Mannynsalo T; Wegelius A; Haaki W; Lahdensuo K; Kajanne R; Kaunisto M; Tuulio-Henriksson A; Kampman O; Hietala J; Veijola J; Lonnqvist J; Isometsa E; Paunio T; Suvisaari J; Kalso E; Niemi M; Tiihonen J; Ahola-Olli A; Daly M; Palotie A
Conference publication: SCHIZOPHRENIA BULLETIN. 2020;46:S250
SOCIODEMOGRAPHIC AND LIFESTYLE FACTORS ASSOCIATED WITH GOOD PERFORMANCE IN PAIRED ASSOCIATES LEARNING TEST IN PATIENTS WITH SCHIZOPHRENIA
Taivalantti M; Barnett J; Torniainen M; Haaki W; Hietala J; Isometsa E; Joutsenniemi K; Jukuri T; Kajanne R; Kampman O; Kieseppa T; Lindberg N; Lahteenvuo M; Lonnqvist J; Suokas K; Suvisaari J; Tiihonen J; Paunio T; Halt A-H; Kerkela M; Jarvelin M-R; Tuulio-Henriksson A; Daly M; Veijola J; Palotie A
Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2020;28(SUPPL 1):69
Polygenic background of psychotic disorders and genetic determinants of disease severity
Ahola-Olli AV; Misiewicz Z; Mars N; Lahteenvuo M; Neale B; Mannynsalo T; Isometsa E; Wegelius A; Hietala J; Haaki W; Kampman O; Veijola J; Tiihonen J; Kieseppa T; Suvisaari J; Hyman S; Daly M; Palotie A
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S48-S49
Risk for disability pension among antidepressant treated patients with and without treatment resistant depression: matched cohort study in Swedish registers
Taipale H; Reutfors J; Tanskanen A; Tiihonen J; Mittendorfer-Rutz E; DiBernardo A; Brandt L; Brenner P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S172
Treatment resistant depression in Stockholm: Disease burden estimations, treatment trajectories and healthcare consumption from a longitudinal population-based cohort
Lundberg J; Hellner C; Leval A; Sjalin M; Ek M; Gannedahl A; Tiihonen J; Loov SA; Cars T
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S209
THE INTERPLAY BETWEEN SCHIZOPHRENIA AND INTELLIGENCE POLYGENIC RISK SCORES CONTRIBUTES TO COMMUNITY FUNCTIONING IN PEOPLE WITH PSYCHOTIC DISORDER
Ahola-Olli A; Misiewicz Z; Mars N; Lahteenvuo M; Neale B; Isometsa E; Hietala J; Kampman O; Veijola J; Tiihonen J; Kieseppa T; Suvisaari J; Hyman S; Daly M; Palotie A
Conference publication: SCHIZOPHRENIA BULLETIN. 2019;45:S174
PSYCHOTIC RELAPSE DURING MAINTENANCE ANTIPSYCHOTIC TREATMENT: A NATIONWIDE STUDY
Rubio J; Taipale H; Correll CU; Tanskanen A; Kane J; Tiihonen J
Conference publication: SCHIZOPHRENIA BULLETIN. 2019;45:S182
NEUROBIOLOGICAL ROOTS OF SCHIZOPHRENIA
Tiihonen J; Koskuvi M; Storvik M; Hyotylainen I; Gao Y; Puttonen K; Giniatullina R; Poguzhelskaya E; Ojansuu I; Vaurio O; Cannon TD; Lonnqvist J; Therman S; Suvisaari J; Kaprio J; Cheng L; Hill A; Lahteenvuo M; Tohka J; Giniatullin R; Lehtonen S; Koistinaho J
Review: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29(4):457-470
Long-acting injectable antipsychotics (LAIs) for maintenance treatment of bipolar and schizoaffective disorders: A systematic review
Pacchiarotti I; Tiihonen J; Kotzalidis GD; Verdolini N; Murru A; Manuel Goikolea J; Valenti M; Aedo A; Vieta E
Review: FRONTIERS IN PSYCHIATRY. 2019;10:1027
A Systematic Literature Review of Neuroimaging of Psychopathic Traits
Johanson M; Vaurio O; Tiihonen J; Lahteenvuo M
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S549
Twenty year follow-up study on antipsychotic treatment, physical morbidity, and mortality in a nationwide cohort of 62,250 patients with schizophrenia (FIN20)
Taipale H; Tanskanen A; Mehtala J; Vattulainen P; Correll CU; Tiihonen J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2019;28:145-146
Temporal changes in the prevalence of cardiovascular drugs use in persons with and without Alzheimer's disease, a retrospective cohort study
Vu M; Koponen M; Taipale H; Tanskanen A; Tiihonen J; Kettunen R; Hartikainen S; Tolppanen A-M
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S375-S376
Suicide mortality and use of psychotropic drugs in patients hospitalized due to bipolar disorder: A Finnish nationwide cohort study
Lahteenvuo M; Concha DA; Tanskanen A; Taipale H; Tiihonen J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2019;44(SUPPL 1):491
Effectiveness of Pharmacological Therapies for Delusional Disorder
Lahteenvuo M; Taipale H; Tanskanen A; Mittendorfer-Rutz E; Tiihonen J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1320-1321
META-ANALYSIS OF CLOZAPINE-ASSOCIATED NEUTROPENIA AND AGRANULOCYTOSIS
Konte B; Walters JT; Giegling I; Legge S; Pardinas AF; Cohen D; Pirmohamed M; Tiihonen J; Hartmann AM; Bogers JP; van der Weide J; van der Weide K; Putkonen A; Repo-Tiihonen E; Hallikainen T; Silva E; Ingimarsson O; Sigurdsson E; Kennedy JL; Breen G; Sullivan P; Rietschel M; Stefansson H; Collier DA; O'Donovan M; Rujescu D
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S866
HLA-DQB1 6672G>C INFLUENCES THE RISK OF CLOZAPINE-INDUCED AGRANULOCYTOSIS IN INDIVIDUALS OF EUROPEAN ANCESTRY
Konte B; Walters J; Giegling I; Legge S; Cohen D; Pirmohamed M; Tiihonen J; Hartmann A; Bogers JP; Van der Weide J; Van der Weide K; Putkonen A; Repo-Tiihonen E; Hallikainen T; Silva E; Ingimarsson O; Sigurdsson E; Kennedy J; Breen G; Sullivan P; Rietschel M; Stefansson H; Collier D; O'Donovan M; Rujescu D
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S939
REPLICATION OF TWO INDEPENDENT LOCI IN HLA-DQB1 AND HLA-B CONTRIBUTING TO THE RISK OF CLOZAPINE-INDUCED AGRANULOCYTOSIS
Konte B; Giegling I; Legge S; Cohen D; Pirmohamed M; Tiihonen J; Hartmann A; Bogers JP; van der Weide J; van der Weide K; Putkonen A; Repo-Tiihonen E; Hallikainen T; Silva E; Ingimarsson O; Sigurdsson E; Kennedy JL; Breen G; Sullivan P; Rietschel M; Stefansson H; Collier DA; O'Donovan M; Rujescu D
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S850
MONOAMINE OXIDASE A (MAOA) GENOTYPE AND METHYLATION MODERATES ASSOCIATIONS OF MALTREATMENT AND AGGRESSION IN WOMEN AND MEN
Checknita D; Bendre M; Ekstrom T; Comasco E; Tiihonen J; Nilsson KW; Hodgins S
Letter: SCHIZOPHRENIA RESEARCH. 2018;202:397
Response to the editorial on antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Tiihonen J
Letter: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(12):1267
Risk of Treatment Failure: Response to Ghosh and Noble
Tiihonen J; Tanskanen A; Taipale H
Letter: AMERICAN JOURNAL OF PSYCHIATRY. 2018;175(9):909
Risk of Treatment Failure: Response to Czobor and Volavka
Tiihonen J; Tanskanen A; Taipale H
Editorial comment: ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2018;47(11):1544-1545
Editorial: let's take a break from studying the PPI-fracture association-Authors' reply
Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Conference publication: SCHIZOPHRENIA BULLETIN. 2018;44:S67
WHAT DOES EPIDEMIOLOGICAL DATA TELL US ABOUT CLOZAPINE'S EFFECTIVENESS?
Tiihonen J
Conference publication: SCHIZOPHRENIA BULLETIN. 2018;44:S88
SLEEP IN MAJOR PSYCHIATRIC DISORDERS: RESULTS FROM NATIONWIDE SUPER FINLAND STUDY
Torniainen-Holm M; Cederlof E; Haaki W; Hietala J; Hakkinen K; Isometsa E; Joutsenniemi K; Jukuri T; Kajanne R; Kampman O; Kieseppa T; Lindberg N; Lahteenvuo M; Lonnqvist J; Mannynsalo T; Niemi-Pynttari J; Suokas K; Suvisaari J; Tiihonen J; Tuulio-Henriksson A; Wegelius A; Veijola J; Palotie A; Paunio T
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:133
Comparison of dispensed medications and forensic-toxicological findings to assess pharmacotherapy in the Swedish population 2006-2013
Tanskanen A; Forsman J; Taipale H; Masterman T; Tiihonen J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:300
Mean number of drugs and prevalence of polypharmacy among community-dwelling persons with and without Alzheimer's disease
Taipale H; Koponen M; Tolppanen A-M; Tiihonen J; Hartikainen S; Tanskanen A
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:290-291
Long-term thiazide use and risk of fractures among persons with alzheimer's disease-nested case-control study
Taipale H; Rysa J; Hukkanen J; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:356
The risk of Alzheimer's disease associated with benzodiazepines and related drugs: A nationwide nested case-control study
Tapiainen V; Taipale H; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:275
Antiepileptic drug use is associated with an increased risk of pneumonia among community-dwelling persons with Alzheimer's disease: A nationwide matched cohort study
Taipale H; Lampela P; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:294
Psychotropic drug use and psychotropic polypharmacy among persons with Alzheimer's disease
Orsel K; Taipale H; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Gardarsdottir H; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:99
20-year nationwide follow-up study on discontinuation of antipsychotic treatment in first-episode schizophrenia
Tiihonen J; Tanskanen A; Taipale H
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:375
Incident opioid use and risk of hip fracture among persons with Alzheimer's disease: A nationwide matched cohort study
Taipale H; Hamina A; Karttunen N; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:293
Antiepileptic drugs and accumulation of hospital days among persons with Alzheimer's disease
Lavikainen P; Taipale H; Tanskanen A; Koponen M; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:95
Hospitalization after oral antibiotic initiation in Finnish community dwellers with and without Alzheimer's disease
Jarvinen H; Taipale H; Koponen M; Tanskanen A; Tiihonen J; Tolppanen A-M; Hartikainen S
Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2018;28:107
Immigrants healthcare utilization before and after being granted disability pension due to common mental disorders: a comparison with Swedish native population
Di Thiene D; Rahman S; Helgesson M; Wang M; Alexanderson K; Tiihonen J; La Torre G; Mittendorfer-Rutz E
Preprint: SSRN ELECTRONIC JOURNAL. 2018
Adherence to Psychotropic Medication in Completed Suicide in Sweden 2006-2013: A Forensic-Toxicological Matched Case-Control Study
Forsman J; Taipale H; Masteman T; Tiihonen J; Tanskanen A
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2018;43:S481-S482
Neurobiological Roots of Schizophrenia
Tiihonen J; Koskuvi M; Storvik M; Hyotylainen I; Gao Y; Puttonen K; Ojansuu I; Vaurio O; Cannon T; Lonnqvist J; Therman S; Suvisaari J; Kaprio J; Cheng L; Hill A; Lahteenvuo M; Tohka J; Giniatullin R; Lehtonen S; Koistinaho J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2018;43:S48
The Debate Regarding Maintenance Treatment With Antipsychotics In Schizophrenia
Davidson M; Goff D; Lieberman J; Krystal J; Murray R; Kahn R; Fleischhacker W; Weiser M; Marder S; Daniel D; Correll C; Tiihonen J; Malaspina D; Sommer I; Buchanan R; Kane J; Rabinowitz J
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2018;43:S296
Use of Psychotrophic Medication and Suicide Mortality in Bipolar Disorder
Lahteenvuo M; Concha DA; Vattulainen P; Tanskanen A; Taipale H; Vieta E; Tiihonen J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:452-453
Proton pump inhibitor use and risk of hip fractures among community-dwelling persons with Alzheimer's disease-A nested case-control study
Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tansakanen A; Tiihonen J; Hartikainen S; Taipale H
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2018;27:289
Antiepileptic drug use and dementia risk-Analyses of Finnish health register and German health insurance data
Taipale H; Gomm W; Broich K; Maier W; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Haenisch B
Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2017;27:ckx189.159
Risk of disability pension in first and second generation immigrants
Di Thiene D; Helgesson M; Alexanderson A; La Torre G; Tiihonen J; Mittendorfer-Rutz E E
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S855-S856
Pharmacological treatments and risk of re-hospitalisation due to unipolar depression in a nationwide cohort of 123,712 patients
Tiihonen J; Tanskanen A; Hoti F; Vattulainen P; Taipale H; Mehtala J; Lahteenvuo M
Letter: LANCET PSYCHIATRY. 2017;4(9):663
Use of lithium in patients with unipolar depression Reply
Tiihonen J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S937
Real-world effectiveness of antipsychotic treatments in a nationwide cohort of 29,823 patients
Tiihonen J; Mittendorfer-Rutz E; Majak M; Mehtala J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Taipale H
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S937-S938
Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Tiihonen J; Mittendorfer-Rutz E; Alexanderson K; Majak M; Mehtala J; Hoti F; Jedenius E; Enkusson D; Leval A; Sermon J; Tanskanen A; Taipale H
Meeting abstract: BIOLOGICAL PSYCHIATRY. 2017;81(10):S98
Disentangling Associations between Antisocial Behavior and Anxiety Disorders with Amygdala-Orbitofrontal Functional and Structural Connectivity in Females
Lindner P; Flodin P; Larm P; Budhiraja M; Savic I; Jokinen J; Tiihonen J; Hodgins S
Conference publication: EUROPEAN PSYCHIATRY. 2017;41:S386
Real-world effectiveness of antipsychotic treatments among patients with schizophrenia and affective symptoms
Tiihonen J; Lahteenvuo M; Hoti F; Vattulainen P; Taipale H; Tanskanen A
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2017;26:488-489
Adjusting for Unobserved Disease Severity Using Individuals as Their Own Controls - An Example from a Schizophrenia Study
Mehtala J; Majak M; Taipale H; Tanskanen A; Tiihonen J; Mittendorfer-Rutz E; Sermon J; Leval A; Hoti F
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2017;42:S604-S605
20-Year Nationwide Follow-Up Study on Antipsychotic Treatment, Re-Hospitalization, and Mortality in First-Episode Schizophrenia (FIN20 Study)
Tiihonen J; Tanskanen A; Taipale H
Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2017;133(1):34-42
Health risks of drugs in Finland - can the risks be managed?
Kauhanen J; Tiihonen J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S313-S314
COPY NUMBER VARIATION ANALYSIS OF A FINNISH COHORT OF CRIMINAL OFFENDERS
Rautiainen M-R; Tiihonen J; Leppa V; Pietilinen O; Lahti J; Liuhanen J; Repo-Tiihonen E; Eriksson J; Virkkunen M; Palotie A; Paunio T
Editorial comment: ACTA PSYCHIATRICA SCANDINAVICA. 2016;134(5):371-373
Real-world effectiveness of antipsychotics
Tuhonen J
Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2016;26:ckw167.048
Mental healthcare use in immigrants granted disability pension due to common mental disorders
Di Thiene D; Rahman S; Helgesson M; Alexanderson K; Tiihonen J; La Torre G; Mittendorfer-Rutz E
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2016;26:S441-S442
Preventing rehospitalization after a manic episode: a population-based comparative cohort study of lithium, antiepileptics and antipsychotics
Wingard L; Brandt L; Boden R; Tiihonen J; Tanskanen A; Kieler H; Andersen M; Reutfors J
Corrigendum: SCHIZOPHRENIA BULLETIN. 2016;42(2):528
Antipsychotic treatment and mortality in schizophrenia (vol 41, pg 656, 2015)
Torniainen M; Mittendorfer-Rutz E; Tanskanen A; Bjorkenstam C; Suvisaari J; Alexanderson K; Tiihonen J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:367
Risk of Pneumonia Associated with Incident Benzodiazepine Use Among Community-Dwelling Persons with Alzheimer's Disease
Taipale H; Tolppanen A-M; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:367-368
Risk Of Stroke Associated With Benzodiazepine And Related Drug Use Among Persons With And Without Alzheimer's Disease
Taipale H; Koponen M; Tanskanen A; Lavikainen P; Tolppanen A-M; Sund R; Tiihonen J; Hartikainen S
Conference publication: GERONTOLOGIST. 2016;56:560
RISK FACTORS FOR HIP FRACTURE IN PEOPLE WITH AND WITHOUT ALZHEIMER'S DISEASE: THE MEDALZ STUDY
Tolppanen A; Taipale H; Tanskanen A; Tiihonen J; Hartikainen SA
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:578-579
Risk Of First Hip Fracture Associated With Incident Benzodiazepine And Related Drug Use In Persons With And Without Alzheimer's Disease
Saarelainen L; Koponen M; Tanskanen A; Tolppanen A-M; Sund R; Tiihonen J; Hartikainen S; Taipale H
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:589
Antipsychotic Use and Risk of Hospitalisation or Death Due to Pneumonia in Persons with and without Alzheimer's Disease
Tolppanen A-M; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S; Taipale H
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:372
Incidence Of Antidepressant Use In Community-Dwelling Persons With And Without Alzheimer's Disease-13-Year Follow-Up
Puranen A; Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:371
Antidepressant Use And Associated Risk Of Hip Fractures Among Community-Dwelling Older Persons With And Without Alzheimer's Disease In Finland
Torvinen-Kiiskinen S; Tolppanen A-M; Koponen M; Tanskanen A; Tiihonen J; Hartikainen S; Taipale H
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:370-371
Antidepressant Use And Associated Risk Of Head And Brain Injuries Among Persons With And Without Alzheimer's Disease
Taipale H; Koponen M; Tanskanen A; Lavikainen P; Sund R; Tiihonen J; Hartikainen S; Tolppanen A-M
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:369
Long-Term Use of Opioids Among Community-Dwelling Persons with and without Alzheimer's Disease
Hamina A; Taipale H; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:366-367
Psychotropic Medication Use and Alzheimer's Disease: A Story of Sex Differences in Two Countries
Moga DC; Taipale H; Tolppanen A-M; Tanskanen A; Tiihonen J; Hartikainen S; Wu Q; Jicha GA; Gnjidic D
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:364-365
Frequent Use Of Psychotropic Drugs Among Persons with Alzheimer's Disease Aged 90 Years Or More In Finland
Taipale H; Koponen M; Tanskanen A; Tolppanen A-M; Tiihonen J; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:363
Risk of Mortality Associated with Antipsychotic Monotherapy and Polypharmacy Among Community-Dwelling Persons with Alzheimer's Disease
Koponen M; Taipale H; Lavikainen P; Tanskanen A; Tiihonen J; Tolppanen A-M; Ahonen R; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:361-362
Antipsychotic Use And The Risk Of Hip Fracture Among Community-Dwelling Persons With Alzheimer's Disease
Koponen M; Taipale H; Lavikainen P; Tanskanen A; Tiihonen J; Tolppanen A-M; Ahonen R; Hartikainen S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2016;25:164-165
Comparing Methods Generating Drug Exposure Time From Prescription Register Data
Tanskanen A; Taipale H; Koponen M; Tolppanen A-M; Hartikainen S; Ahonen R; Tiihonen J
Conference publication: AUSTRALASIAN JOURNAL ON AGEING. 2016;35:19
Sex differences in psychotropic medication use in older people with Alzheimer's disease: a story of two countries
Gnjidic D; Moga D; Taipale H; Tolppanen AM; Tanskanen PL; Tiihonen J; Hartikainen S; Wu Q; Jicha GA
Conference publication: BIOLOGICAL PSYCHIATRY. 2016;79(9):255S
Cortical and Subcortical Abnormalities in Young Women Who Presented Conduct Disorder Prior to Age 15
Budhiraja M; Pereiera JB; Lindner P; Westman E; Jokinen J; Savic I; Tiihonen J; Hodgins S
Conference publication: BIOLOGICAL PSYCHIATRY. 2016;79(9):93S-94S
Among Females, Differential Methylation in a Subregion of the Monoamine Oxidase A (MAOA) Gene Promoter Associates with Conduct Disorder, the Experience of Physical and Sexual Abuse, and Timing of Sexual Abuse
Checknita D; Comasco E; Oreland L; Rehn M; Westerman J; Ekstrom TJ; Nilsson KW; Tiihonen J; Hodgins S
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2016;41:S359-S360
Real-World Effectiveness of Pharmacological Treatments in Severe Unipolar Depression in a Nationwide Cohort of 123,712 Patients
Tiihonen J; Lahteenvuo M; Hoti F; Vattulainen P; Tanskanen A
Conference publication: BIOLOGICAL PSYCHIATRY. 2016;79(9):233S
MAO Levels and Interpersonal Violence in Suicide Attempters
Konigsson J; Moberg T; Oreland L; Tiihonen J; Asberg M; Jokinen J
Review: EUROPEAN PSYCHIATRY. 2015;30(8):1037-1047
Long-term use of benzodiazepines: Definitions, prevalence and usage patterns - a systematic review of register-based studies
Kurko TAT; Saastamoinen LK; Tahkapaa S; Tuulio-Henriksson A; Taiminen T; Tiihonen J; Airaksinen MS; Hietala J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25:S596
Increased [³h]quisqualic acid binding density in the dorsal striatum of alcoholics
Laukkanen V; Kupila J; Karkkainen O; Kautiainen H; Tiihonen J; Storvik M
Letter: WORLD PSYCHIATRY. 2015;14(2):245-247
Psychotropic drugs and homicide: A prospective cohort study from Finland
Tiihonen J; Lehti M; Aaltonen M; Kivivuori J; Kautiainen H; Virta LJ; Hoti F; Tanskanen A; Korhonen P
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2015;40:S211-S212
Mortality and Cumulative Exposure to Antipsychotics, Antidepressants and Benzodiazepines: An Observational Follow-Up Study
Tiihonen J; Mittendorfer-Rutz E; Torniainen M; Alexanderson K; Tanskanen A
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S658
Decreased [³H] naloxone binding density in the dentate gyrus of Cloninger type 1 alcoholics
Laukkanen V; Karkkainen O; Kautiainen H; Tiihonen J; Storvik M
Letter: MOLECULAR PSYCHIATRY. 2014;19(4):403-405
Exome sequence analysis of Finnish patients with clozapine-induced agranulocytosis
Tiwari AK; Need AC; Lohoff FW; Zai CC; Chowdhury NI; Mueller DJ; Putkonen A; Repo-Tiihonen E; Hallikainen T; Yagcioglu AEA; Tiihonen J; Kennedy JL; Meltzer HY
Conference publication: BIOLOGICAL PSYCHIATRY. 2014;75(9):243S
Disentangling Structural Brain Anomalies in Young Women with Prior Conduct Disorder: Impact of Substance Misuse and Physical and Sexual Abuse
Budhiraja M; Lindner P; Jokinen J; Savic-Berglund I; Tiihonen J; Hodgins S
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2014;23:251
Medication and Risk of Rehospitalization in Bipolar Disorder: A Nationwide Cohort Study
Reutfors J; Tiihonen J; Brandt L; Scheen L; Tanskanen A; Andersen M; Boden R
Conference publication: BIPOLAR DISORDERS. 2014;16:95-96
Mood-stabilizing medication after hospitalization for bipolar disorder in Sweden: a register-based cohort study
Reutfors J; Scheen L; Brandt L; Boden R; Tanskanen A; Andersen M; Tiihonen J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2014;23:368-369
Clinical Factors Associated with Prescription Filling of Mood-Stabilizers in Bipolar Disorder - A Population-Based Cohort Study
Scheen L; Boden R; Brandt L; Tiihonen J; Andersen M; Kieler H; Reutfors J
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2014;23:342
Incidence of Antipsychotic Use in Relation to Diagnosis of Alzheimer's Disease among Community-Dwelling Persons: Nationwide Population Based Study
Hartikainen S; Koponen M; Taipale H; Tolppanen A-M; Tiihonen J; Tanskanen A; Johnell K; Fastbom J
Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2014;130(17):1721-1730
[Investments of research and treatment of brain diseases will pay of time].
Lindsberg PJ; Castrén E; Korkeila J; Alho H; Erkinjuntti T; Isometsä E; Kalso E; Marttunen M; Pihko H; Tienari P; Wartiovaara A; Jäkälä P; Kälviäinen R; Soininen H; Tiihonen J; Karlsson H; Rinne J; Roine RO; Elovaara I; Tamminen T; Ohman J; Majamaa K; Hari R
Letter: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2013;23(4):338
Clozapine resistance-Augmentation strategies
Tiihonen J; Leucht S
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40:S273
Brain nor-β-CIT Binding Is Related to the Short Term Heart Rate and Cardiac Repolarisation Interval Variability on ECG in l Homozygotes by Serotonin Transporter Gene Polymorphism (5-HTTLPR)
Kauppila E; Lipponen J; Tarvainen M; Kaurijoki S; Karhunen L; Pietilainen H; Rissanen A; Kaprio J; Pesonen U; Tiihonen J; Vanninen E
Review: JOURNAL OF PSYCHOPHARMACOLOGY. 2012;26(S5):27-32
Examining the effectiveness of antipsychotic medication in first-episode psychosis
Taylor M; Cavanagh J; Hodgson R; Tiihonen J
Corrigendum: AMERICAN JOURNAL OF PSYCHIATRY. 2012;169(2):223
A Nationwide Cohort Study of Oral and Depot Antipsychotics After First Hospitalization for Schizophrenia (vol 168, pg 603, 2011)
Tiihonen J
Book chapter: PSYCHODYNAMIC PSYCHOTHERAPY RESEARCH: CURRENT CLINICAL PSYCHIATRY. 2012;p. 219-232
Toward Molecular Psychotherapy of Depression?
Lehtonen J; Tiihonen J; Joensuu MMO; Lehto SM; Ahola PO; Saarinen PI; Valkonen-Korhonen M; Tolmunen T; Kuikka JT
Conference publication: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2012;21:328
Twelve-Year Trend in Treatment Seeking for Buprenorphine, Heroin and Amphetamine Abuse in Finland
Uosukainen H; Kauhanen J; Voutilainen S; Fohr J; Paasolainen M; Tiihonen J; Laitinen K; Onyeka IN; Bell JS
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2012;53
Serotonin genotype and relations between daylight duration and brain 5-HTT binding
Kauppila E; Vanninen E; Kaurijoki S; Karhunen L; Pietilainen K; Rissanen A; Kaprio J; Tiihonen J; Pesonen U; Kuikka J
Corrigendum: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2011;20(10):1113
Association between medication and risk of suicide, attempted suicide and death in nationwide cohort of suicidal patients with schizophrenia (vol 17, pg 686, 2008)
Haukka J; Tiihonen J; Haerkaenen T; Loennqvist J
Letter: SCHIZOPHRENIA RESEARCH. 2011;131(1-3):260-261
The place of observational studies in assessing the effectiveness of depot antipsychotics
Haddad PM; Tiihonen J; Haukka J; Taylor M; Patel MX; Korhonen P
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2011;35(4):1080-1086
More evidence on proneurocognitive effects of add-on mirtazapine in schizophrenia
Stenberg J-H; Terevnikov V; Joffe M; Tiihonen J; Tchoukhine E; Burkin M; Joffe G
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S333
Relations between autonomic cardiovascular stress responses and brain 5-HTT binding may depend on serotonin genotype
Kauppila E; Vanninen E; Kuusela T; Kaurijoki S; Karhunen L; Pietilainen KH; Rissanen A; Kaprio J; Tiihonen J; Pesonen U; Kuikka J
Conference publication: SCHIZOPHRENIA RESEARCH. 2010;117(2-3):377
EFFECTS OF ADD-ON MIRTAZAPINE ON NEUROCOGNITION IN SCHIZOPHRENIA: AN OPEN LABEL EXTENSION PHASE OF A DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY, AND BOTH PHASES
Stenberg JH; Terevnikov V; Joffe M; Tiihonen J; Tchoukhine E; Burkin M; Joffe G
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2010;37:S249-S250
Dependence of twin-to-twin serotonin transporter binding similarity on genotype in monozygotic twins
Kauppila E; Vanninen E; Kaurijoki S; Karhunen L; Pietilainen KH; Rissanen A; Kaprio J; Tiihonen J; Kuikka J
Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2010;13:45
Brain serotonin transporter availability in panic disorder: Gender differences and implications for treatment response to escitalopram
Maron E; Toeru I; Hirvonen J; Vasar V; Shlik J; Nutt DJ; Tiihonen J; Hietala J
Letter: LANCET. 2009;374(9701):1592-1593
Mortality in patients with schizophrenia Author's reply
Tiihonen J
Letter: PSYCHIATRY RESEARCH. 2009;172(3):251
Altered hemispheric balance of temporal cortex dopamine D_2/3 receptor binding in major depressive disorder
Lehto SM; Kuikka J; Tolmunen T; Hintikka J; Viinamaki H; Vanninen R; Koivumaa-Honkanen H; Honkalampi K; Tiihonen J
Conference publication: DRUG AND ALCOHOL REVIEW. 2009;28:A35
RANDOMISED CONTROLLED TRIAL OF METHYLPHENIDATE FOR METHAMPHETAMINE DEPENDENCE; HOW IS IT GOING?
Kydd R; Miles W; Hardley P; Wheeler A; Jensen M; Lorusso M; Russell B; Sheridan J; Tiihonen J
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2009;36:S389
Relations between cardiac repolarization time interval and striatal dopamine transporter binding during valsalva manouvre
Kauppila E; Vanninen E; Kuusela T; Kaurijoki S; Karhunen L; Pietilainen KH; Rissanen A; Kaprio J; Tiihonen J; Kuikka J
Conference publication: PROCEEDINGS OF THE 21ST IEEE INTERNATIONAL SYMPOSIUM ON COMPUTER-BASED MEDICAL SYSTEMS. 2008;:242-247
Predicting forensic admission among the mentally ill:: A Bayesian approach
Soini EJO; Rissanen T; Tiihonen J; Eronen M; Hodgins S; Ryynanen O-P
Conference publication: JOURNAL OF AFFECTIVE DISORDERS. 2008;107:S84
Antidepressant use and mortality in Finland:: A register-linkage study from a nationwide cohort
Haukka J; Arffman M; Partonen T; Sihvo S; Tiihonen J; Lonnqvist J
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2008;32(1):229-237
Changes in midbrain serotonin transporter availability in atypically depressed subjects after one year of psychotherapy
Lehto SM; Tolmunen T; Joensuu M; Saarinen PI; Valkonen-Korhonen M; Vanninen R; Ahola P; Tiihonen J; Kuikka J; Lehtonen J
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2008;35:S216-S217
Cardiac repolarisation and striatal dopamine transporter function are interrelated
Kauppila E; Vanninen E; Kuusela T; Kaurijoki S; Karhunen L; Pietilainen K; Rissanen A; Kaprio J; Tiihonen J; Kuikka J
Conference publication: EUROPEAN PSYCHIATRY. 2007;22:S55-S56
Real-world effectiveness of Pharmacological treatments in schizophrenia
Tiihonen J; Wahlbeck K; Lonngvist J; Klaukka T; Ioannidis JPA; Volavka J; Haukka J
Conference publication: VALUE IN HEALTH. 2006;9(6):A316-A317
Predicting violent offending among mentally ill in a multinational setting-naive Bayesian fusion and model merging with P-course
Soini EJ; Rissanen T; Tiihonen J; Hodgins S; Eronen M; Ryynaenen OP
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2006;30(7):1251-1255
Midbrain binding of [¹²³I]nor-β-CIT in atypical depression
Lehto S; Tolmunen T; Joensuu M; Saarinen PI; Vanninen R; Ahola P; Tiihonen J; Kuikka J; Lehtonen J
Review: COCHRANE DATABASE OF SYSTEMATIC REVIEWS. 2006;2006(2):CD003730
Glutamatergic drugs for schizophrenia
Tuominen HJ; Tiihonen J; Wahlbeck K
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2006;16:S321
Antidepressant use and the risk of suicide, attempted suicide and overall mortality in a nation-wide cohort
Tiihonen J; Lonnqvist J; Wahlbeck K; Klaukka T; Tanskanen A; Haukka J
Conference publication: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2006;21:105
Antidepressants and the risk of suicide, attempted suicide and overall mortality in a nation-wide cohort
Haukka JK; Tiihonen J; Wahlbeck K; Klaukka T; Loennqvist J
Letter: AMERICAN JOURNAL OF PSYCHIATRY. 2006;163(1):161
Fatal agranulocytosis 4 years after discontinuation of clozapine
Tiihonen J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2005;15:S480
Effectiveness of antipsychotic treatments in first-episode schizophrenia
Tiihonen J; Wahlbeck K; Lönnqvist J; Klaukka T; Ioannidis JPA; Volavka J; Haukka J
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2005;32:S92-S93
Relations between cardiovascular stress, serotonin transporter promoter gene polymorphism and regional brain serotonin activity in man
Kauppila E; Kaurijoki S; Karhunen L; Kaprio J; Tiihonen J; Kuikka J; Vanninen E
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2004;28(8):1221-1247
Dopamine and alcoholism: neurobiological basis of ethanol abuse
Tupala E; Tiihonen J
Meeting abstract: ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH. 2004;28(8):75A
The medial temporal lobe in alcoholism and psychopathology: Evaluation by volumetric MRI.
Laakso MP; Vaurio O; Savolainen L; Tiihonen E; Soininen H; Tiihonen J; Aronen HJ
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2004;31:S289
Serotonergic activity in thalamus is associated to diastolic blood pressure in humans
Kauppila E; Kuikka J; Hämäläinen S; Karhunen L; Rissanen A; Kaprio J; Tiihonen J; Vanninen E
Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2004;7:S254
Real-world outcome of antipsychotic treatment.: A 7-year follow-up study of a nationwide cohort of 3232 patients with first episode schizophrenia
Tiihonen J; Wahlbeck K; Lönnqvist J; Klaukka T; Haukka J
Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2004;7:S25-S26
Lamotrigine treatment for schizophrenia: Rationale and outcome
Tiihonen J
Conference publication: EUROPEAN PSYCHIATRY. 2004;19:24S
The scope of brain imaging in the research of the outcome of psychotherapy
Lehtonen J; Saarinen P; Kuikka J; Joensuu M; Tolmunen T; Ahola P; Tiihonen J
Conference publication: EUROPEAN PSYCHIATRY. 2004;19:24S-25S
Outcome of psychodynamic psychotherapy measured by [123I]nor-CIT SPET imaging
Joensuu M; Saarinen P; Tolmunen T; Kuikka J; Tiihonen J; Ahola P; Lehtonen J
Conference publication: JOURNAL OF AFFECTIVE DISORDERS. 2004;78:S139
Premorbid intellectual functioning in schizophrenia and bipolar disorders
Tiihonen J; Haukka J; Henriksson M; Cannon M; Kieseppa T; Laaksonen I; Sinivuo J; Lonnqvist J
Conference publication: SCHIZOPHRENIA RESEARCH. 2004;67(1):236-237
Evidence for a different pattern of premorbid intellectual functioning in schizophrenia and bipolar disorder: Results from a cohort study of male conscripts
Tiihonen J; Haukka J
Book chapter: BOOKS OF ABSTRACTS OF THE 16TH WORLD CONGRESS OF THE INTERNATIONAL ASSOCIATION FOR CHILD AND ADOLESCENT PSYCHIATRY AND ALLIED PROFESSIONS (IACAPAP). 2004;p. 253-384
Poster
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Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2003;13:S358-S359
Reduced brain serotonin transporter binding in patients with panic disorder
Maron E; Kuikka JT; Shlik J; Vasar V; Vanninen E; Tiihonen J
Published conference paper: NEUROIMAGE. 2003;19(1):145-155
Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography
Tupala E; Hall H; Mantere T; Räsänen P; Särkioja T; Tiihonen J
Published conference paper: INFLAMMATION RESEARCH. 2003;52:S37-S38
Alcoholics show altered histaminergic neurotransmission in several cortical areas -: Preliminary report
Alakärppä K; Tupala E; Mantere T; Särkioja T; Räsänen P; Tarhanen J; Tiihonen J; Tuomisto L
Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2003;119(24):2494-2500
[Neural basis of alcohol dependence].
Kiianmaa K; Tiihonen J; Hyytiä P
Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 2003;57(2):109-110
Amelioration of negative symptoms of schizophrenia with glutamatergic drugs: a systematic review and meta-analysis
Tuominen HJ; Tiihonen J; Wahlbeck K
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2002;12:S263
Lamotrigine in clozapine-resistant schizophrenia:: A randomized placebocontrolled cross-over trial
Tiihonen J; Hallikainen T; Ryynänen OP; Tiihonen ER; Kotilainen I; Eronen M; Toivonen P; Wahlbeck K; Putkonen A
Book chapter: COCHRANE DATABASE OF SYSTEMATIC REVIEWS: CLINICAL RESPIRATORY JOURNAL. 2002;p.
Glutamatergic drugs for schizophrenia
Tuominen HJ; Wahlbeck K; Tiihonen J
Conference publication: EUROPEAN PSYCHIATRY. 2002;17:212S
Dopamine D2 receptors and transporters in type 1 and 2 alcoholics
Tupala E; Hall H; Bergstöm K; Mantere T; Räsänen P; Särkioja T; Tiihonen J
Published conference paper: INFLAMMATION RESEARCH. 2002;51:S40-S41
Effect of alcohol abuse on human brain histamine and tele-methylhistamine
Alakärppä K; Tupala E; Mantere T; Särkioja T; Räsänen P; Tarhanen J; Tiihonen J; Tuomisto L
Review: SUICIDE AND LIFE-THREATENING BEHAVIOR. 2002;32(2):191-208
Use of statistical techniques in studies of suicide seasonality, 1970 to 1997
Hakko H; Räsänen P; Tiihonen J; Nieminen P
Published conference paper: ACTA PSYCHIATRICA SCANDINAVICA, SUPPLEMENT. 2002;106(412):54-57
The quantitative risk of violent crime and criminal offending:: a case-control study among the offspring of recidivistic Finnish homicide offenders
Putkonen A; Ryynänen OP; Eronen M; Tiihonen J
Review: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2001;88(6):287-293
Dopamine transporter in vitro binding and in vivo imaging in the brain
Bergström KA; Tupala E; Tiihonen J
Letter: PSYCHOPHARMACOLOGY. 2001;155(1):113-114
Cluster C personality disorder has no independent effect on striatal dopamine transporter densities in major depression
Laasonen-Balk T; Viinamäki H; Kuikka J; Husso-Saastamoinen M; Lehtonen J; Halonen P; Tiihonen J
Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 2001;55(2):82
Dopamine in major depression
Hietala J; Kajander J; Viinamäki H; Tiihonen J; Ilonen T; Solin O; Bergman J; Eskola O; Syvälahti E
Conference publication: MONITORING MOLECULES IN NEUROSCIENCE. 2001;:181-182
What does dopamine overflow in the nucleus accumbens during self-stimulation represent?
Yavich L; Tiihonen J
Book chapter: CLINICAL ASSESSMENT OF DANGEROUSNESS. 2000;p. 121-135
Recidivistic Violent Behavior and Axis I and Axis II Disorders
Tiihonen J
Conference publication: EUROPEAN PSYCHIATRY. 2000;15:249S
SPET studies on outcome of treatment by psychosocial interventions in depression and hysterical paresthesia
Lehtonen J; Kuikka J; Viinamäki H; Tiihonen J; Husso-Saastamoinen M
Editorial comment: MOLECULAR PSYCHIATRY. 2000;5(4):347-348
CYP2A6 genotype and smoking
Tiihonen J; Pesonen U; Kauhanen J; Koulu M; Hallikainenz T; Leskinen L; Salonen T
Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 2000;116(4):409-415
[Functional brain imaging in psychiatry].
Karhu J; Kuikka J; Tiihonen J
Book chapter: BIOMAG 96: PROCEEDINGS OF THE TENTH INTERNATIONAL CONFERENCE ON BIOMAGNETISM, VOLS I & II. 2000;p. 1026-1029
Reversed hemispheric asymmetry of auditory N100m in schizophrenics
Karhu J; Tiihonen J; Pekkonen E; Katila H; Huotilainen M; Virtanen J; Ilmoniemi R
Book chapter: VIOLENCE AMONG THE MENTALLY ILL. 2000;p. 171-191
Pharmacological intervention for preventing violence among the mentally ill with secondary alcohol- and drug-use disorders
Tiihonen J; Swartz MS
Book chapter: BIOMAG 96: PROCEEDINGS OF THE TENTH INTERNATIONAL CONFERENCE ON BIOMAGNETISM, VOLS I & II. 2000;p. 1014-1017
MEG and MCG in a clinical environment:: BioMag Laboratory, Helsinki
Ilmoniemi RJ; Ahonen A; Alho K; Aronen HJ; Huttunen J; Karhu J; Karp P; Mäkijärvi M; Näätänen R; Paetau R; Pekkonen E; Standertskjöld-Nordenstam CG; Tiihonen J; Toivonen L; Katila T
Conference publication: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 2000;96(4):519
CYP2A6 genotype and cigarette smoking.
Tiihonen J; Pesonen U; Kauhanen J; Koulu M; Hallikainen T; Leskinen L; Salonen JT
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2000;27(1):S90
Altered serotonin transporter density in obese binge eating women:: Initial findings
Kuikka J; Tammela L; Rissanen A; Bergström K; Muhonen M; Vanninen E; Karhunen L; Karhu J; Tiihonen J; Uusitupa M
Letter: JOURNAL OF CLINICAL PSYCHIATRY. 1999;60(9):619-620
Transient syncope and ECG changes associated with the concurrent administration of clozapine and diazepam
Tupala E; Niskanen L; Tiihonen J
Letter: ARCHIVES OF GENERAL PSYCHIATRY. 1999;56(3):283-284
Is a large body size during childhood a risk factor for later aggression?
Räsänen P; Hakko H; Järvelin MR; Tiihonen J
Letter: SCHIZOPHRENIA RESEARCH. 1999;35(2):183-185
Schizophrenia and seasonality of admissions:: the Northern Finland 1966 birth cohort study
Räsänen P; Hakko H; Järvelin MR; Isohanni M; Tiihonen J
Book chapter: ADVANCES IN PHARMACOLOGICAL SCIENCES. 1999;p. 25-30
Comparison of iodine-123 labelled nor-β-CIT and β-CIT as potential radioligands for serotonin transporter imaging
Kuikka JT; Bergström KA; Åkerman K; Tiihonen J
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1999;26(9):972
Dopamine transporter and D₂-receptor density in late onset type 1 alcoholics
Kuikka JT; Repo E; Bergström KA; Karhu J; Hiltunen J; Tiihonen J
Conference publication: MOLECULAR PSYCHIATRY. 1999;4:S16-S17
Ethanol consumption and DRD2 gene Taq1 'A' polymorphism in an unselected human population.
Hallikainen T; Hietala J; Kauhanen J; Pohjalainen T; Syvälahti E; Salonen JT; Tiihonen J
Conference publication: SCHIZOPHRENIA RESEARCH. 1999;36(1-3):48
Mortality and physical morbidity among patients with schizophrenia:: A prospective study of the northern Finland 1966 general population birth cohort
Mäkikyrö T; Räsänen P; Karvonen JT; Jones P; Hakko H; Nieminen P; Moring J; Koiranen M; Tiihonen J; Järvelin MR; Joukamaa M; Isohanni M
Book chapter: ADVANCES IN PHARMACOLOGICAL SCIENCES. 1999;p. 19-23
First evaluation in humans of [¹²³I]PE2I:: A selective radioligand for visualization of the striatal dopamine transporter density
Bergström KA; Kuikka JT; Emond P; Hiltunen J; Halldin C; Guilloteau D; Mauclaire L; Yu M; Karhu J; Tupala E; Tiihonen J
Letter: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 1998;27(5):929-930
Parental age gap and child sex ratio -: Fact or fiction?
Hakko H; Räsänen P; Järvelin MR; Tiihonen J
Conference publication: INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY. 1998;30(1-2):34
Altered frontal lobe function suggested by ERP generator analysis in impulsive violent alcoholics
Tarkka IM; Karhu J; Kuikka J; Tiihonen J
Review: ANNALS OF MEDICINE. 1998;30(3):242-248
Fractal analysis - a new approach in brain receptor imaging
Kuikka J; Tiihonen J
Meeting abstract: SCHIZOPHRENIA RESEARCH. 1998;29(1-2):22
Schizophrenia, alcohol abuse and violent behaviour
Räsänen P; Tiihonen J; Isohanni M; Rantakallio P; Lehtonen J; Moring J
Review: DUODECIM; LAAKETIETEELLINEN AIKAKAUSKIRJA. 1998;114(10):993-1001
[What's new in neuropharmacology?].
Castrén E; Männistö PT; Tiihonen J
Conference publication: AMERICAN JOURNAL OF MEDICAL GENETICS PART A. 1998;81(6):516
Association between the genetic polymorphism of the of the catechol-O-methyltransferase (COMT) and type 1 alcoholism.
Tiihonen J; Hallikainen T; Lachman H; Volavka J; Hietala J; Pohjalainen T; Ryynänen OP; Kauhanen J
Conference publication: NORDIC JOURNAL OF PSYCHIATRY. 1998;52:72
Brain receptor imaging in substance abuse and anxiety disorders
Tiihonen J
Conference publication: 1ST INTERNATIONAL CONFERENCE ON PROTECTING THE ENVIRONMENT - IN PROCESS INDUSTRY. 1998;(30):27-32
Environmental risk analysis for accidental releases in the process industry
Malmen Y; Tiihonen J; Wessberg N
Letter: COGNITIVE AND BEHAVIORAL NEUROLOGY. 1997;10(4):260-262
Benzodiazepine receptor uptake in a patient with panic disorder after citalopram treatment
Tiihonen J; Lepola U; Kuikka J
Conference publication: RADIOLOGY. 1997;205:730
Fractal analysis of striatal dopamine re-uptake sites in type 1 and type 2 alcoholics
Kuikka JT; Tiihonen J; Bergstrom KA
Conference publication: SCHIZOPHRENIA RESEARCH. 1997;24(1-2):256
Schizophrenia, alcohol abuse and violent behaviour - A 26-year follow-up study of an unselected birth cohort
Rasanen P; Tiihonen J; Isohanni M; Rantakallio P; Lehtonen J; Moring J
Conference publication: SCHIZOPHRENIA RESEARCH. 1997;24(1-2):251-252
The predictors of schizophrenia in the 1966 Northern Finland birth cohort study
Isohanni M; Rantakallio P; Jones P; Hakko H; Isohanni I; Moring J; Myhrman A; Makikyro T; Rasanen P; Rasanen S; Tiihonen J
Conference publication: INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY. 1997;25(1):49
Impaired adaptation to external input in impulsive violent alcoholics
Karhu J; Paakkonen A; Kuikka J; Bergstrom K; Partanen J; Tiihonen J
Conference publication: INTERNATIONAL CONGRESS AND SYMPOSIUM SERIES - ROYAL SOCIETY OF MEDICINE. 1997;222:27-28
Major mental disorders and violent behaviour
Tiihonen J
Letter: BRITISH JOURNAL OF PSYCHIATRY. 1996;168(4):520-521
Low incidence of mania in northern Finland
Veijola J; Rasanen P; Isohanni M; Tiihonen J
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 1996;37(5):172
Altered dopamine transporter densities in patients with social phobia.
Kuikka JT; Tiihonen J; Bergstrom KA; Lepola U; Koponen H; Leinonen E; Lansimies E
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 1996;37(5):296
Initial human studies with SPECT using [I-123]NNC 13-8241 for visualization of benzodiazepine receptors.
Kuikka JT; Bergstrom KA; Halldin C; Hiltunen J; Foged C; Akerman KK; Tiihonen J; Farde L
Letter: BRITISH JOURNAL OF PSYCHIATRY. 1995;167(6):821
Homicidal behaviour and mental disorders
Tiihonen J; Hakola P; Eronen M
Published conference paper: NUCLEAR MEDICINE AND BIOLOGY. 1995;22(8):971-976
THE METABOLITE PATTERN OF [I-123] BETA-CIT DETERMINED WITH A GRADIENT HPLC METHOD
BERGSTROM KA; HALLDIN C; KUIKKA JT; SWAHN CG; TIIHONEN J; HILTUNEN J; LANSIMIES E; FARDE L
Other: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 1995;22(7):682-686
I-123 LABELED N-(2-FLUOROETHYL)-2-BETA-CARBOMETHOXY-3-BETA-(4-IODOPHENYL)NORTROPANE FOR DOPAMINE TRANSPORTER IMAGING IN THE LIVING HUMAN BRAIN
KUIKKA JT; AKERMAN K; BERGSTROM KA; KARHU J; HILTUNEN J; HAUKKA J; HEIKKINEN J; TIIHONEN J; WANG SY; NEUMEYER JL
Other: SYNAPSE-STRUCTURE FUNCTION CONNECTIVITY. 1995;19(4):297-300
LIPOPHILIC METABOLITE OF [I-123] BETA-CIT IN HUMAN PLASMA MAY OBSTRUCT QUANTITATION OF THE DOPAMINE TRANSPORTER
BERGSTROM KA; HALLDIN C; KUIKKA JT; SWAHN CG; TIIHONEN J; HILTUNEN J; LANSIMIES E; FARDE L
Letter: BIOLOGICAL PSYCHIATRY. 1995;37(2):134-135
ALTERED CEREBRAL BLOOD PLOW DURING HYSTERICAL PARESTHESIA
TIIHONEN J; KUIKKA J; VIINAMAKI H; LEHTONEN J; PARTANEN J
Letter: AMERICAN JOURNAL OF PSYCHIATRY. 1995;152(11):1695-1696
PITFALLS OF SPECT STUDIES OF ACUTE ETHANOL-INDUCED CHANGES IN CEREBRAL BLOOD-FLOW - REPLY
TIIHONEN J; KUIKKA J
Book chapter: ADVANCES IN PHARMACOLOGICAL SCIENCES. 1995;p. 345-350
ACUTE ETHANOL-INDUCED CHANGES IN CEREBRAL BLOOD-FLOW
KUIKKA J; TIIHONEN J; HAKOLA P; PAANILA J; AIRAKSINEN J; ERONEN M; HALLIKAINEN T
Book chapter: ADVANCES IN BIOMAGNETISM. 1989;p. 121-124
Paired Tone Presentation Enhances Responses of Human Auditory Cortex to Rare Frequency Changes
Rif J; Hari R; Tiihonen J
Book chapter: ADVANCES IN BIOMAGNETISM. 1989;p. 169-172
Evoked and Spontaneous Magnetic Activity of the Human Somatosensory Cortex
Tiihonen J; Hari R; Kajola M; Hämäläinen M
Preprint: BIORXIV.
Oligodendrocyte precursor cells engulf synapses in a model of the developing human forebrain
Gkogka A; Malwade S; Koskuvi M; Bose R; Ceccatelli S; Koistinaho J; Tiihonen J; Schalling M; Samudyata; Sellgren CM
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Professor/Specialist Physician, Department of Clinical Neuroscience, Karolinska Institutet, 2025-2025

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Docent, University of Kuopio, 1992

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