Ioannis Mantas

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Articles

Journal article: NATURE COMMUNICATIONS. 2024;15(1):8176
Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.
Mantas I; Flais I; Masarapu Y; Ionescu T; Frapard S; Jung F; Le Merre P; Saarinen M; Tiklova K; Salmani BY; Gillberg L; Zhang X; Chergui K; Carlén M; Giacomello S; Hengerer B; Perlmann T; Svenningsson P
Journal article: F1000RESEARCH. 2024;13:1017
Muscarinic receptor agonists in animal models of psychosis: protocol for a systematic review and meta-analysis
Siafis S; Nomura N; Schneider-Thoma J; Bighelli I; Bannach-Brown A; Ramage FJ; Tinsdeall F; Mantas I; Jauhar S; Natesan S; Vernon AC; de Bartolomeis A; Hölter SM; Drude NI; Tölch U; Hansen W-P; Chiocchia V; Howes OD; Priller J; Macleod MR; Salanti G; Leucht S
Journal article: JOURNAL OF COMPARATIVE NEUROLOGY. 2024;532(7):e25651
Excitatory Projections of Wide Field Collicular Neurons to the Nucleus of the Optic Tract in the Rat
Tzanou A; Theodorou E; Mantas I; Dalezios Y
Journal article: ELIFE. 2024;12
Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
Yaghmaeian Salmani B; Lahti L; Gillberg L; Jacobsen JK; Mantas I; Svenningsson P; Perlmann T
Article: ELIFE. 2024;12:RP89482
Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
Salmani BY; Lahti L; Gillberg L; Jacobsen JK; Mantas I; Svenningsson P; Perlmann T
Journal article: WELLCOME OPEN RESEARCH. 2024;9:182
Trace amine-associated receptor 1 (TAAR1) agonism for psychosis: a living systematic review and meta-analysis of human and non-human data.
Siafis S; Chiocchia V; Macleod MR; Austin C; Homiar A; Tinsdeall F; Friedrich C; Ramage FJ; Kennett J; Nomura N; Maksym O; Rutigliano G; Vano LJ; McCutcheon RA; Gilbert D; Ostinelli EG; Stansfield C; Dehdarirad H; Juma DO; Wright S; Simple O; Elugbadebo O; Tonia T; Mantas I; Howes OD; Furukawa TA; Milligan L; Moreno C; Elliott JH; Hastings J; Thomas J; Michie S; Sena ES; Seedat S; Egger M; Potts J; Cipriani A; Salanti G; Leucht S
Article: NPJ PARKINSON'S DISEASE. 2023;9(1):56
Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice
Skiteva O; Yao N; Mantas I; Zhang X; Perlmann T; Svenningsson P; Chergui K
Article: WELLCOME OPEN RESEARCH. 2023;8:365
Trace amine-associated receptor 1 (TAAR1) agonists for psychosis: protocol for a living systematic review and meta-analysis of human and non-human studies.
Siafis S; McCutcheon R; Chiocchia V; Ostinelli EG; Wright S; Stansfield C; Juma DO; Mantas I; Howes OD; Rutigliano G; Ramage F; Tinsdeall F; Friedrich C; Milligan L; Moreno C; Elliott JH; Thomas J; Macleod MR; Sena ES; Seedat S; Salanti G; Potts J; Cipriani A; Leucht S; GALENOS team
Article: NEUROPSYCHOPHARMACOLOGY. 2022;47(13):2319-2329
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT_1A receptor agonist SEP-383856
Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ; Svenningsson P
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(22):14290
Impaired Aversive Memory Formation in GPR37L1KO Mice
Veenit V; Zhang X; Paslawski W; Mantas I; Svenningsson P
Article: ACS CHEMICAL BIOLOGY. 2022;17(1):147-158
Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems
Fridjonsdottir E; Vallianatou T; Mantas I; Shariatgorji R; Nilsson A; Schembri LS; Odell LR; Svenningsson P; Andren PE
Article: MOLECULAR PSYCHIATRY. 2021;26(12):7308-7315
Ependymal cells-CSF flow regulates stress-induced depression
Seo J-S; Mantas I; Svenningsson P; Greengard P
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(16):8907
Trace Amine-Associated Receptor 1 Contributes to Diverse Functional Actions of O-Phenyl-Iodotyramine in Mice but Not to the Effects of Monoamine-Based Antidepressants
Mantas I; Millan MJ; Di Cara B; Groenink L; Veiga S; Cistarelli L; Brocco M; Bertrand M; Svenningsson P; Zhang X
Article: BIOLOGICAL PSYCHIATRY. 2021;90(1):16-27
TAAR1-Dependent and-Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition
Mantas I; Vallianatou T; Yang Y; Shariatgorji M; Kalomoiri M; Fridjonsdottir E; Millan MJ; Zhang X; Andren PE; Svenningsson P
Article: MOLECULAR PSYCHIATRY. 2021;26(7):3253-3265
P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness
Sousa VC; Mantas I; Stroth N; Hager T; Pereira M; Jiang H; Jabre S; Paslawski W; Stiedl O; Svenningsson P
Article: NEUROPHARMACOLOGY. 2020;174:108136
NMDA receptors are altered in the substantia nigra pars reticulata and their blockade ameliorates motor deficits in experimental parkinsonism
Sitzia G; Mantas I; Zhang X; Svenningsson P; Chergui K
Article: FRONTIERS IN AGING NEUROSCIENCE. 2020;12:84
Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37
Zhang X; Mantas I; Fridjonsdottir E; Andren PE; Chergui K; Svenningsson P
Article: NEUROPHARMACOLOGY. 2020;162:107829
Genetic deletion of GPR88 enhances the locomotor response to L-DOPA in experimental parkinsonism while counteracting the induction of dyskinesia
Mantas I; Yang Y; Mannoury-la-Cour C; Millan MJ; Zhang X; Svenningsson P
Article: NATURE METHODS. 2019;16(10):1021-1028
Comprehensive mapping of neurotransmitter networks by MALDI-MS imaging
Shariatgorji M; Nilsson A; Fridjonsdottir E; Vallianatou T; Kallback P; Katan L; Savmarker J; Mantas I; Zhang X; Bezard E; Svenningsson P; Odell LR; Andren PE
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(17):E4247-4247
Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex
Lazarevic V; Mantas I; Flais I; Svenningsson P
Article: FRONTIERS IN PHARMACOLOGY. 2018;9:166
Striatal Tyrosine Hydroxylase Is Stimulated via TAAR1 by 3-Iodothyronamine, But Not by Tyramine or β-Phenylethylamine
Zhang X; Mantas I; Alvarsson A; Yoshitake T; Shariatgorji M; Pereira M; Nilsson A; Kehr J; Andren PE; Millan MJ; Chergui K; Svenningsson P
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All other publications

Preprint: BIORXIV. 2024
A striosomal accumbens pathway drives compulsive seeking behaviors through an aversive Esr1+ hypothalamic-habenula circuit
Contesse T; Bektash BY; Graziano M; Forastieri C; Contestabile A; Hahne S; Jung F; Nikolakopoulou I; Cao X; Skara V; Mantas I; Giatrellis S; Carlén M; Sandberg R; Calvigioni D; Meletis K
Preprint: BIORXIV. 2023
Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
Yaghmaeian Salmani B; Lahti L; Gillberg L; Jacobsen JK; Mantas I; Svenningsson P; Perlmann T
Corrigendum: NEUROPSYCHOPHARMACOLOGY. 2023;48(5):846
TAAR1 dependent and independent actions of the potential antipsychotic and dual TAAR1/5-HT_1A receptor agonist SEP- 363856 (vol 47, pg 2319, 2022)
Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ; Svenningsson P
Preprint: RESEARCH SQUARE. 2022
Aberrant somatic L- and T-type calcium channel function in cNurr1 and LRRK2-G2019S mice
Chergui K; Skiteva O; Yao N; Mantas I; Zhang X; Perlmann T; Svenningsson P
Thesis / dissertation: 2022
Regulation of monoaminergic functions by GPCRs with a special emphasis on mental and movement disorders
Mantas, Ioannis
Review: MOLECULAR PSYCHIATRY. 2022;27(1):534-558
Update on GPCR-based targets for the development of novel antidepressants
Mantas I; Saarinen M; Xu Z-QD; Svenningsson P
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2022;47:391
TAAR1 Dependent and Independent Actions of the Potential Antipsychotic and Dual TAAR1/5HT1A Receptor Agonist SEP-383856
Svenningson P; Saarinen M; Mantas I; Flais I; Agren R; Sahlholm K; Millan MJ

Employments

Postdoctoral Researcher, Department of Neuroscience, Karolinska Institutet, 2022-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2022

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