Hong Jin

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Articles

Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2024;81(1):331

PIEZO1 targeting in macrophages boosts phagocytic activity and foam cell apoptosis in atherosclerosis

Pourteymour S; Fan J; Majhi RK; Guo S; Sun X; Huang Z; Liu Y; Winter H; Baecklund A; Skenteris N-T; Chernogubova E; Werngren O; Li Z; Skogsberg J; Li Y; Matic L; Hedin U; Maegdefessel L; Ehrenborg E; Tian Y; Jin H
Article: ADVANCED HEALTHCARE MATERIALS. 2024;13(6):e2302907

Utilization of an Artery-on-a-Chip to Unravel Novel Regulators and Therapeutic Targets in Vascular Diseases

Paloschi V; Pauli J; Winski G; Wu Z; Li Z; Botti L; Meucci S; Conti P; Rogowitz F; Glukha N; Hummel N; Busch A; Chernogubova E; Jin H; Sachs N; Eckstein H-H; Dueck A; Boon RA; Bausch AR; Maegdefessel L
Article: MOLECULAR THERAPY. 2023;31(6):1775-1790

Targeting long non-coding RNA NUDT6 enhances smooth muscle cell survival and limits vascular disease progression

Winter H; Winski G; Busch A; Chernogubova E; Fasolo F; Wu Z; Baecklund A; Khomtchouk BB; Booven DJV; Sachs N; Eckstein H-H; Wittig I; Boon RA; Jin H; Maegdefessel L
Article: DIABETES. 2022;71(2):285-297

Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes

Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2022;9:831039

Inhibition of IL17A Using an Affibody Molecule Attenuates Inflammation in ApoE-Deficient Mice

Kumawat AK; Zegeye MM; Paramel GV; Baumgartner R; Gistera A; Amegavie O; Hellberg S; Jin H; Caravaca AS; Soderstrom LA; Gudmundsdotter L; Frejd FY; Ljungberg LU; Olofsson PS; Ketelhuth DFJ; Sirsjo A
Article: CIRCULATION. 2021;144(19):1567-1583

Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization

Fasolo F; Jin H; Winski G; Chernogubova E; Pauli J; Winter H; Li DY; Glukha N; Bauer S; Metschl S; Wu Z; Koschinsky ML; Reilly M; Pelisek J; Kempf W; Eckstein H-H; Soehnlein O; Matic L; Hedin U; Baecklund A; Bergmark C; Paloschi V; Maegdefessel L
Article: EUROPEAN HEART JOURNAL. 2021;42(39):4077-4088

Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis

Hinterdobler J; Schott S; Jin H; Meesmann A; Steinsiek A-L; Zimmermann A-S; Wobst J; Mueller P; Mauersberger C; Vilne B; Baecklund A; Chen C-S; Moggio A; Braster Q; Molitor M; Krane M; Kempf WE; Ladwig K-H; Hristov M; Hulsmans M; Hilgendorf I; Weber C; Wenzel P; Scheiermann C; Maegdefessel L; Soehnlein O; Libby P; Nahrendorf M; Schunkert H; Kessler T; Sager HB
Article: CURRENT OPINION IN PHARMACOLOGY. 2021;60:183-192

MicroRNA: A mediator of diet-induced cardiovascular protection

Collado A; Jin H; Pernow J; Zhou Z
Article: CELLS. 2021;10(6):1276

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

Seime T; Akbulut AC; Liljeqvist ML; Siika A; Jin H; Winski G; van Gorp RH; Karlof E; Lengquist M; Buckler AJ; Kronqvist M; Waring OJ; Lindeman JHN; Biessen EAL; Maegdefessel L; Razuvaev A; Schurgers LJ; Hedin U; Matic L
Journal article: CIRCULATION. 2021;144(19):1567-1583

Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization

Fasolo F; Jin H; Winski G; Chernogubova E; Pauli J; Winter H; Li DYY; Glukha N; Bauer S; Metschl S; Wu Z; Koschinsky ML; Reilly M; Pelisek J; Kempf W; Eckstein H-H; Soehnlein O; Matic L; Hedin U; Backlund A; Bergmark C; Paloschi V; Maegdefessel L
Article: BIOENGINEERING & TRANSLATIONAL MEDICINE. 2021;6(1):e10193

Sonodynamic therapy reduces iron retention of hemorrhagic plaque

Li B; Gong J; Sheng S; Lu M; Guo S; Yao J; Zhang H; Zhao X; Cao Z; Sun X; Wang H; Cao Y; Jiang Y; Tian Z; Liu B; Zhao H; Zhang Z; Jin H; Tian Y
Article: SCIENTIFIC REPORTS. 2020;10(1):11638

Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits

Yao J; Zhao X; Tan F; Cao X; Guo S; Li X; Huang Z; Diabakte K; Wang L; Liu M; Shen Z; Li B; Cao Z; Sheng S; Lu M; Cao Y; Jin H; Zhang Z; Tian Y
Article: REDOX BIOLOGY. 2020;32:101501

Non-lethal sonodynamic therapy facilitates the M1-to-M2 transition in advanced atherosclerotic plaques via activating the ROS-AMPK-mTORC1-autophagy pathway

Yang Y; Wang J; Guo S; Pourteymour S; Xu Q; Gong J; Huang Z; Shen Z; Diabakte K; Cao Z; Wu G; Natalia S; Tian Z; Jin H; Tian Y
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2020;5(1):53-65

Sonodynamic Therapy Suppresses Neovascularization in Atherosclerotic Plaques via Macrophage Apoptosis-Induced Endothelial Cell Apoptosis

Yao J; Gao W; Wang Y; Wang L; Diabakte K; Li J; Yang J; Jiang Y; Liu Y; Guo S; Zhao X; Cao Z; Chen X; Li Q; Zhang H; Wang W; Tian Z; Li B; Tian F; Wu G; Pourteymour S; Huang X; Tan F; Cao X; Yang Z; Li K; Zhang Y; Li Y; Zhang Z; Jin H; Tian Y
Article: CIRCULATION. 2019;139(21):2466-2482

Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability

Centa M; Jin H; Hofste L; Hellberg S; Busch A; Baumgartner R; Verzaal NJ; Enoksson SL; Matic LP; Boddul SV; Atzler D; Li DY; Sun C; Hansson GK; Ketelhuth DFJ; Hedin U; Wermeling F; Lutgens E; Binder CJ; Maegdesfessel L; Malin SG
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2019;4(1):72-82

miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease

Eken SM; Christersdottir T; Winski G; Sangsuwan T; Jin H; Chernogubova E; Pirault J; Sun C; Simon N; Winter H; Backlund A; Haghdoost S; Hansson GK; Halle M; Maegdefessel L
Article: PLOS ONE. 2019;14(6):e0217511

Membrane-permeabilized sonodynamic therapy enhances drug delivery into macrophages

Cao Z; Zhang T; Sun X; Liu M; Shen Z; Li B; Zhao X; Jin H; Zhang Z; Tian Y
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2018;3(6):719-727

Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms

Petri MH; Thul S; Andonova T; Lindquist-Liljeqvist M; Jin H; Skenteris N-T; Arnardottir H; Maegdefessel L; Caidahl K; Perretti M; Roy J; Back M
Article: CIRCULATION. 2018;138(15):1551-1568

H19 Induces Abdominal Aortic Aneurysm Development and Progression

Li DY; Busch A; Jin H; Chernogubova E; Pelisek J; Karlsson J; Sennblad B; Liu S; Lao S; Hofmann P; Baecklund A; Eken SM; Roy J; Eriksson P; Dacken B; Ramanujam D; Dueck A; Engelhardt S; Boon RA; Eckstein H-H; Spin JM; Tsao PS; Maegdefessel L
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2018;56(1):102-109

Four Surgical Modifications to the Classic Elastase Perfusion Aneurysm Model Enable Haemodynamic Alterations and Extended Elastase Perfusion

Busch A; Chernogubova E; Jin H; Meurer F; Eckstein H-H; Kim M; Maegdefessel L
Article: MOLECULAR THERAPY. 2018;26(4):1040-1055

Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions

Jin H; Li DY; Chernogubova E; Sun C; Busch A; Eken SM; Saliba-Gustafsson P; Winter H; Winski G; Raaz U; Schellinger IN; Simon N; Hegenloh R; Matic LP; Jagodic M; Ehrenborg E; Pelisek J; Eckstein H-H; Hedin U; Backlund A; Maegdefessel L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(8):1907-1912

Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

Di Gennaro A; Araujo AC; Busch A; Jin H; Wagsater D; Vorkapic E; Caidahl K; Eriksson P; Samuelsson B; Maegdefessel L; Haeggstrom JZ
Article: CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2018;47(1):83-96

5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Alleviates Atherosclerosis via Enhancing Efferocytosis and Facilitating a Shift in the Th1/Th2 Balance Toward Th2 Polarization

Yang Y; Liu Y; Chen X; Gong J; Huang Z; Wang W; Shi Y; Wang Y; Yao J; Shen Z; Tian Z; Jin H; Tian Y
Article: THERANOSTICS. 2018;8(18):4969-4984

Sonodynamic therapy-induced foam cells apoptosis activates the phagocytic PPARγ-LXRα-ABCA1/ABCG1 pathway and promotes cholesterol efflux in advanced plaque

Wang H; Yang Y; Sun X; Tian F; Guo S; Wang W; Tian Z; Jin H; Zhang Z; Tian Y
Article: CIRCULATION JOURNAL. 2017;81(12):1945-1952

Increased Carotid Artery Lesion Inflammation Upon Treatment With the CD137 Agonistic Antibody 2A

Soderstrom LA; Jin H; Caravaca AS; Klement ML; Li Y; Gistera A; Hedin U; Maegdefessel L; Hansson GK; Olofsson PS
Article: CIRCULATION RESEARCH. 2017;120(4):633-644

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions

Eken SM; Jin H; Chernogubova E; Li Y; Simon N; Sun C; Korzunowicz G; Busch A; Backlund A; Osterholm C; Razuvaev A; Renne T; Eckstein HH; Pelisek J; Eriksson P; Diez MG; Matic LP; Schellinger IN; Raaz U; Leeper NJ; Hansson GK; Paulsson-Berne G; Hedin U; Maegdefessel L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(9):1947-1961

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM

Matic LP; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Rohl S; Kronqvist M; Aldi S; Magne J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojevic V; Lehtio J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: THROMBOSIS AND HAEMOSTASIS. 2016;115(5):969-978

Dok-1 negatively regulates platelet integrin αIIbβ3 outside-in signalling and inhibits thrombosis in mice

Niki M; Nayak MK; Jin H; Bhasin N; Plow EF; Pandolfi PP; Rothman PB; Chauhan AK; Lentz SR
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(9):1945-1953

Local MicroRNA Modulation Using a Novel Anti-miR21-Eluting Stent Effectively Prevents Experimental In-Stent Restenosis

Wang D; Deuse T; Stubbendorff M; Chernogubova E; Erben RG; Eken SM; Jin H; Li Y; Busch A; Heeger C-H; Behnisch B; Reichenspurner H; Robbins RC; Spin JM; Tsao PS; Schrepfer S; Maegdefessel L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(5):1226-1235

ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability

Magne J; Gustafsson P; Jin H; Maegdefessel L; Hultenby K; Wernerson A; Eriksson P; Franco-Cereceda A; Kovanen PT; Goncalves I; Ehrenborg E
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2015;35(4):838-844

Endothelial PPAR-γ Protects Against Vascular Thrombosis by Downregulating P-Selectin Expression

Jin H; Gebska MA; Blokhin IO; Wilson KM; Ketsawatsomkron P; Chauhan AK; Keen HL; Sigmund CD; Lentz SR
Article: NATURE COMMUNICATIONS. 2014;5:5214

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development

Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nagakami F; Heymann HM; Chernugobova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Article: DIABETES & VASCULAR DISEASE RESEARCH. 2014;11(2):121-124

Resistin increases platelet P-selectin levels via p38 MAPK signal pathway

Qiu W; Chen N; Zhang Q; Zhuo L; Wang X; Wang D; Jin H
Article: MOLECULAR MEDICINE REPORTS. 2012;5(4):923-928

Hydrogen sulfide attenuates cardiac hypertrophy and fibrosis induced by abdominal aortic coarctation in rats

Huang J; Wang D; Zheng J; Huang X; Jin H
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2011;24(4):386-393

Urantide alleviates monocrotaline induced pulmonary arterial hypertension in Wistar rats

Mei Y; Jin H; Tian W; Wang H; Wang H; Zhao Y; Zhang Z; Meng F
Article: THROMBOSIS RESEARCH. 2011;128(1):42-46

Asymmetric dimethylarginine impairs fibrinolytic activity in human umbilical vein endothelial cells via p38 MAPK and NF-κB pathways

Zhang Q; Chen N; Qiu W; Xu X; Wang D; Tsao PS; Jin H
Article: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION. 2011;34(2):e36-e42

Resistin level is positively correlated with thrombotic complications in Southern Chinese metabolic syndrome patients

Fang WQ; Zhang Q; Peng YB; Chen M; Lin XP; Wu JH; Cai CH; Mei YF; Jin H
Article: ENDOCRINOLOGY. 2011;152(1):59-68

Apelin Decreases Lipolysis via G_q, G_i, and AMPK-Dependent Mechanisms

Yue P; Jin H; Xu S; Aillaud M; Deng AC; Azuma J; Kundu RK; Reaven GM; Quertermous T; Tsao PS
Article: BLOOD COAGULATION & FIBRINOLYSIS. 2010;21(5):420-424

Mitogen-activated protein kinases pathway is involved in physiological testosterone-induced tissue factor pathway inhibitor expression in endothelial cells

Jin H; Wang D-Y; Mei Y-F; Qiu W-B; Zhou Y; Wang D-M; Tan X-R; Li Y-G
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2010;298(1):E59-E67

Apelin is necessary for the maintenance of insulin sensitivity

Yue P; Jin H; Aillaud M; Deng AC; Azuma J; Asagami T; Kundu RK; Reaven GM; Quertermous T; Tsao PS
Article: ASIAN JOURNAL OF ANDROLOGY. 2009;11(2):266-271

Testosterone alleviates tumor necrosis factor-alpha-mediated tissue factor pathway inhibitor downregulation via suppression of nuclear factor-kappa B in endothelial cells

Jin H; Qiu W-B; Mei Y-F; Zhang Q; Wang D-M; Li Y-G; Tan X-R
Article: CHINESE MEDICAL JOURNAL. 2001;114(3):266-269

Relationship between gene polymorphism of the PAI-1 promoter and myocardial infarction

Fu L; Jin H; Song KN; Zhang CL; Shen JX; Huang YL
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Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2018;68(2):656

Four Surgical Modifications to the Classic Elastase Perfusion Aneurysm Model Enable Haemodynamic Alterations and Extended Elastase Perfusion

Busch A; Chernogubova E; Jin H; Meurer F; Eckstein HH; Kim M; Maegdefessel L
Meeting abstract: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38

Nudt6 Inhibition Limits Smooth Muscle Cell Apoptosis and Abdominal Aortic Aneurysm Progression

Jin H; Winter H; Chernogubova E; Li Y; Winski G; Backlund A; Maegdefessel L
Meeting abstract: TRANSPLANTATION. 2017;101(5):S28

Local microRNA Modulation is a Suitable Way to Prevent In-Stent Restenosis and Coronary Allograft Arteriosclerosis

Wang D; Deuse T; Stubbendorff M; Chernogubova E; Erben RG; Eken SM; Jin H; Heeger C; Behnisch B; Reichenspurner H; Robbins RC; Spin JM; Tsao PS; Maegdefessel L; Schrepfer S
Meeting abstract: ATHEROSCLEROSIS. 2015;241(1):E1-E2

ATG16L1 EXPRESSION IN CAROTID ATHEROSCLEROTIC PLAQUES IS ASSOCIATED WITH PLAQUE VULNERABILITY

Magne J; Gustafsson P; Jin H; Maegdefessel L; Hultenby K; Wernerson A; Eriksson P; Franco-Cereceda A; Kovanen PT; Goncalves I; Ehrenborg E
Meeting abstract: JOURNAL OF HEART AND LUNG TRANSPLANTATION. 2015;34(4):S39

Coronary Allograft Arteriosclerosis: Local MicroRNA Modulation Using a Novel Anti-Mir-21-Eluting Stent Prevents in-Stent Restenosis

Wang D; Deuse T; Stubbendorff M; Chernogubova E; Erben RG; Eken SM; Jin H; Heeger C; Behnisch B; Reichenspurner H; Robbins RC; Spin JM; Tsao PS; Maegdefessel L; Schrepfer S
Corrigendum: NATURE COMMUNICATIONS. 2015;6:6506

miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development (vol 5, 5214, 2014)

Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nakagami F; Heymann HM; Chernogubova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Review: JOURNAL OF DIABETES RESEARCH. 2013;2013:834727-10

Making Sense in Antisense: Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction

Eken SM; Jin H; Chernogubova E; Maegdefessel L
Published conference paper: BIOCHEMISTRY AND CELL BIOLOGY. 2007;85(2):246-251

Physiological testosterone stimulates tissue plasminogen activator and tissue factor pathway inhibitor and inhibits plasminogen activator inhibitor type 1 release in endothelial cells

Jin H; Lin J; Fu L; Mei Y-F; Peng G; Tan X; Wang D-M; Wang W; Li Y-G

Employments

Senior Research Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-

Degrees and Education

Docent, Harbin Medical University

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