Håkan Wallén

Publications
CV
Public outreach and news

Articles

Article: PLATELETS. 2026;37(1):2614709
Prediction of bleeding and thromboembolic complications in patients on chronic hemodialysis with the total thrombus-formation analysis system
Dimitrijevic ZM; Apostolovic S; Tasic DD; Cvetkovic TP; Lazarevic MV; Hozokawa K; Agren A; Wallen H
Article: ESC HEART FAILURE. 2026;13(3):xvag105
Worse long-term outcomes in new-onset HFpEF vs HFrEF and HFmrEF: findings from the Stockholm PREFERS study
Persson H; Winderud A; Hage C; Cabrera CC; Lofstrom U; Lynga P; Arslan T; Malmqvist KK; Eriksson MJ; Persson B; Wallen H; Ekstrom M; Linde C
Article: CLINICAL NUTRITION. 2026;58:106584
Bariatric surgery improves fibrinolysis in individuals with obesity with and without concomitant type 2 diabetes
Andersson M; Thorell A; Henriksson P; Kallner A; Wallen H; Lindahl TL; Agren A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;110(10):e3193-e3202
Influence of Bariatric Surgery on Endothelial and Glycocalyx Biomarkers in Obesity and Type 2 Diabetes
Andersson M; Agren A; Henriksson P; Wallen H; Thorell A
Article: UPSALA JOURNAL OF MEDICAL SCIENCES. 2025;130:e12006
Elevated levels of aquaporin-4-containing extracellular vesicles in cerebrospinal fluid of patients with bipolar disorder
Wetterberg L; Mobarrez F; Nybom R; Wallen H; Pelanis A; von Rosen D; Landen M
Article: EUROPEAN HEART JOURNAL OPEN. 2025;5(2):oeaf014
Baseline characteristics and 1-year outcome by left ventricular function in the CABG PREFERS
Lofstrom U; Linde C; Eriksson MJ; Maret E; Corbascio M; Ekstrom M; Lynga P; Wallen H; Persson B; Persson H; Hage C
Article: PLATELETS. 2024;35(1):2437768
Alterations in platelet activity and endothelial glycocalyx biomarkers by treatment with an angiotensin converting enzyme inhibitor or an alpha-1 adrenoceptor antagonist in patients with hypertension: results from the DoRa study
Ekholm M; Jekell A; Lundwall K; Alfredsson J; Lindahl TL; Wallen H; Kahan T
Article: ESC HEART FAILURE. 2024;11(5):2661-2671
Iron deficiency in new onset heart failure: association with clinical factors and quality of life
Cabrera CC; Ekstrom M; Tornvall P; Lofstrom U; Frisk C; Linde C; Hage C; Persson H; Eriksson MJ; Wallen H; Persson B; Lynga P
Article: SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. 2024;84(4):257-267
Effects of dabigatran, rivaroxaban, and apixaban on fibrin network permeability, thrombin generation, and fibrinolysis
Taune VS; Zabczyk M; He S; Agren A; Blomback M; Wallen H; Skeppholm M
Article: ATHEROSCLEROSIS. 2024;390:117335
Use of heated tobacco products (IQOS) causes an acute increase in arterial stiffness and platelet thrombus formation
Lyytinen G; Melnikov G; Brynedal A; Anesater E; Antoniewicz L; Blomberg A; Wallen H; Bosson JA; Hedman L; Tehrani S; Lundback M
Article: CLINICAL KIDNEY JOURNAL. 2024;17(3):sfae050
Associations between inflammatory and angiogenic proteomic biomarkers, and cardiovascular events and mortality in relation to kidney function
Salzinger B; Lundwall K; Evans M; Moertberg J; Wallen H; Jernberg T; Kahan T; Lundman P; Tornvall P; Erlinge D; Lindahl B; Baron T; Rezeli M; Spaak J; Jacobson SH
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2023;21(11):3166-3174
Neutrophil extracellular trap formation is an independent risk factor for occult cancer in patients presenting with venous thromboembolism
Rosell A; Gautam G; Wannberg F; Ng H; Gry H; Vingback E; Lundstrom S; Mackman N; Wallen H; Westerlund E; Thalin C
Article: CARDIOVASCULAR TOXICOLOGY. 2023;23(7-8):255-264
Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial
Lyytinen G; Brynedal A; Anesater E; Antoniewicz L; Blomberg A; Wallen H; Bosson JA; Hedman L; Mobarrez F; Tehrani S; Lundback M
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2023;379:82-88
Relationship between iron deficiency and expression of genes involved in iron metabolism in human myocardium and skeletal muscle
Cabrera C; Frisk C; Lofstrom U; Lynga P; Linde C; Hage C; Persson H; Eriksson MJ; Wallen H; Persson B; Ekstrom M
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2023;373:64-71
Prognostic importance of biomarkers associated with haemostatic, vascular and endothelial disturbances in acute coronary syndrome patients in relation to kidney function
Mortberg J; Salzinger B; Lundwall K; Edfors R; Jacobson SH; Wallen HN; Jernberg T; Baron T; Erlinge D; Andell P; James S; Eggers KM; Hjort M; Kahan T; Lundman P; Tornvall P; Rezeli M; Marko-Varga G; Lindahl B; Spaak J
Article: ONCOIMMUNOLOGY. 2022;11(1):2049487
Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress
Cedervall J; Herre M; Dragomir A; Rabelo-Melo F; Svensson A; Thalin C; Rosell A; Hjalmar V; Wallen H; Lindman H; Pejler G; Hagstrom E; Hultstrom M; Larsson A; Olsson AK
Article: FRONTIERS IN CARDIOVASCULAR MEDICINE. 2022;9:952974
Extracellular vesicles in heart failure - A study in patients with heart failure with preserved ejection fraction or heart failure with reduced ejection fraction characteristics undergoing elective coronary artery bypass grafting
Matan D; Mobarrez F; Lofstrom U; Corbascio M; Ekstrom M; Hage C; Lynga P; Persson B; Eriksson M; Linde C; Persson H; Wallen H
Article: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. 2022;6(7):e12823
Antithrombotic treatment switching in elderly patients with atrial fibrillation and the risk of thromboembolism, bleeding, and cardiac death
Ehrlinder H; Orsini N; Modig K; Wallen H; Gigante B
Article: INTERNATIONAL UROLOGY AND NEPHROLOGY. 2022;54(10):2695-2702
Platelet thrombus formation in patients with end-stage renal disease before and after hemodialysis as measured by the total thrombus-formation analysis system
Mitic BP; Dimitrijevic ZM; Hosokawa K; Cvetkovic TP; Lazarevic MV; Tasic DD; Jovanovic A; Jancic N; Vrecic T; Agren A; Wallen H
Article: OPEN HEART. 2022;9(2):e002080
Is the association of QTc with atrial fibrillation and stroke in cohort studies a matter of time?
Radnahad N; Ehrlinder H; Leander K; Engdahl J; Wallen H; Gigante B
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All other publications

Review: EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY. 2024;10(7):614-645
Update on antithrombotic therapy and body mass: a clinical consensus statement of the European Society of Cardiology Working Group on Cardiovascular Pharmacotherapy and the European Society of Cardiology Working Group on Thrombosis
Gigante B; Tamargo J; Agewall S; Atar D; ten Berg J; Campo G; Cerbai E; Christersson C; Dobrev D; Ferdinandy P; Geisler T; Gorog DA; Grove EL; Kaski JC; Rubboli A; Wassmann S; Wallen H; Rocca B
Review: UPSALA JOURNAL OF MEDICAL SCIENCES. 2024;129(1)
COVID-19: Not a thrombotic disease but a thromboinflammatory disease
He S; Blomback M; Wallen H
Corrigendum: BMC NEUROLOGY. 2022;22(1):337
IL6 trans-signaling associates with ischemic stroke but not with atrial fibrillation (vol 21, 306, 2021)
Ziegler L; Wallen H; Aspberg S; de Faire U; Gigante B
Letter: EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY. 2021;7(3):e31
Themultiplication of loaves and fishes approach: a critic to double anti-thrombotics or to double number of ischaemic events? Response
Komen JJ; Forslund T; Mantel-Teeuwisse AK; Klungel OH; von Euler M; Braunschweig F; Wallen H; Hjemdahl P
Review: SEMINARS IN THROMBOSIS AND HEMOSTASIS. 2021;47(01):63-73
The Clotting Trigger Is an Important Determinant for the Coagulation Pathway In Vivo or In Vitro-Inference from Data Review
He S; Cao H; Thalin C; Svensson J; Blomback M; Wallen H
Corrigendum: TRIALS. 2020;21(1):388
Update on the EFFECTS study of fluoxetine for stroke recovery: a randomised controlled trial in Sweden (vol 21, 233, 2020)
Lundstrom E; Isaksson E; Nasman P; Wester P; Martensson B; Norrving B; Wallen H; Borg J; Dennis M; Mead G; Hankey GJ; Hackett ML; Sunnerhagen KS
Editorial: JOURNAL OF CARDIAC FAILURE. 2020;26(5):440-443
Increased iron absorption in patients with chronic heart failure and iron deficiency
Cabrera CC; Ekstrom M; Linde C; Persson H; Hage C; Eriksson MJ; Wallen H; Persson B; Tornvall P; Lynga P
Study protocol: TRIALS. 2020;21(1):233
Update on the EFFECTS study of fluoxetine for stroke recovery: a randomised controlled trial in Sweden
Lundstrom E; Isaksson E; Nasman P; Wester P; Martensson B; Norrving B; Wallen H; Borg J; Dennis M; Mead G; Hankey GJ; Hackett ML; Sunnerhagen KS
Review: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2019;39(9):1724-1738
Neutrophil Extracellular Traps Villains and Targets in Arterial, Venous, and Cancer-Associated Thrombosis
Thalin C; Hisada Y; Lundstrom S; Mackman N; Wallen H
Review: LAKARTIDNINGEN. 2019;116:FI3S
[The neutrophil's multifaceted traps - the Dr Jekyll and Mr Hyde of the immune system].
Thålin C; Rosell A; Lundström S; Wallén H
Review: LAKARTIDNINGEN. 2018;115:FAH6
[Improved stroke prevention in atrial fibrillation: the Stockholm experience of the introduction of NOACs].
Hjemdahl P; Braunschweig F; Holmström M; Johnsson H; von Euler M; Wallén H; Forslund T
Letter: LAKARTIDNINGEN. 2017;114:EM9X
Replik till Ola Samuelsson och Aso Saeed: - Läkemedelsverket ser över skrivningen.
Almquist T; Erichsen S; Wallén H
Letter: THROMBOSIS RESEARCH. 2017;151:63-66
Global impairments in the haemostasis systems after cardiopulmonary bypass
He S; Blomback M; Wallen H; Jeppsson A; Grass S
Corrigendum: THROMBOSIS RESEARCH. 2016;147:63
Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays (vol 139, pg 90, 2016)
Hisada Y; Alexander W; Kasthuri R; Voorhees P; Mobarrez F; Taylor A; McNamara C; Wallen H; Witkowski M; Key NS; Rauch U; Mackman N
Review: THROMBOSIS RESEARCH. 2016;139:90-97
Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays
Hisada Y; Alexander W; Kasthuri R; Voorhees P; Mobarrez F; Taylor A; McNamara C; Wallen H; Witkowski M; Key NS; Rauch U; Mackman N
Letter: DIABETES CARE. 2014;37(11):e244
Increased Incorporation of Antiplasmin Into the Fibrin Network in Patients With Type 1 Diabetes. Diabetes Care 2014; 37: 2007-2014
Agren A; Jorneskog G; Elgue G; Henriksson P; Wallen H; Wiman B
Letter: JOURNAL OF HYPERTENSION. 2013;31(10):2103-2104
Platelet activation during exercise is not attenuated by inhibition of the renin-angiotensin system: the role of physical activity Reply
Kahan T; Schwieler JH; Wallen H; Nussberger J; Hjemdahl P
Letter: JOURNAL OF HYPERTENSION. 2013;31(9):1917
Exercise-induced platelet activation in essential hypertension: have we solved the puzzle? Reply
Kahan T; Schwieler JH; Wallen H; Nussberger J; Hjemdahl P
Letter: CIRCULATION. 2013;127(11):e505
Letter by Hjemdahl et al Regarding Article, "Periprocedural Bleeding and Thromboembolic Events With Dabigatran Compared With Warfarin: Results From the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Randomized Trial"
Hjemdahl P; Johnsson H; Wallen NH
Letter: THROMBOSIS RESEARCH. 2012;129(1):95-97
Release of endothelial microparticles in vivo during atorvastatin treatment; a randomized double-blind placebo-controlled study
Mobarrez F; Egberg N; Antovic J; Broijersen A; Jorneskog G; Wallen H
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Employments

Professor Emeritus, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2025-2028
Adjunct Professor, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2014-2025

Degrees and Education

Docent, Karolinska Institutet, 1999

Supervision

Supervision to doctoral degree
- Bergen Karin, Microvesicles, skin microcirculation and clinical microangiopathy in type 1 diabetes, 2022
- Josefin Mörtberg, Platelet microparticles and hemostatic disturbances in renal insufficiency and cardiovascular disease, 2019
- Ehrlinder Hanne, Förmaksflimmer: Risker och vinster med antikoagulation hos äldre

Articles

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Employments

Degrees and Education

Supervision

Supervision to doctoral degree

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