Gunnar Nilsson

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About me

Gunnar P. Nilsson was appointed Professor of Experimental Allergy Research at Karolinska Institutet in 2008. His research is mainly focused on understanding the role of the mast cell in asthma and other inflammatory diseases – and to find ways to inhibit it locally in order to stop or reduce chronic inflammation.

Articles

Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2024;26(9):792-804
Plasma Protein Profiling to Discern Indolent from Advanced Systemic Mastocytosis
Iribarren C; Levedahl KH; Atanasoai I; Mattsson M; Hoglund M; Soderlund S; Hagglund H; Eriksson N; Carlson M; Nilsson GP
Article: ACTA ONCOLOGICA. 2024;63:44-50
Epidemiology of mastocytosis: a population-based study (Sweden)
Bergstrom A; Hagglund H; Berglund A; Nilsson G; Lambe M
Article: FRONTIERS IN IMMUNOLOGY. 2024;15:1393802
An optimized method for IgE-mediated degranulation of human lung mast cells
Gong Y; Johnsson A-K; Safholm J; Al-Ameri M; Sachs E; Vali K; Nilsson G; Ronnberg E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: IN PRACTICE. 2023;11(6):1706-1717
European Competence Network on Mastocytosis (ECNM): 20-Year Jubilee, Updates, and Future Perspectives
Valent P; Hartmann K; Bonadonna P; Sperr W; Niedoszytko M; Kluin-Nelemans HC; Hermine O; Sotlar K; Hoermann G; Nedoszytko B; Broesby-Olsen S; Zanotti R; Lange M; Doubek M; Brockow K; Alvarez-Twose I; Varkonyi J; Yavuz S; Nilsson G; Radia D; Grattan C; Schwaab J; Gillen T; Elberink HNGO; Haegglund H; Siebenhaar F; Hadzijusufovic E; Sabato V; Mayer J; Reiter A; Orfao A; Horny H-P; Triggiani M; Arock M
Article: JOURNAL OF IMMUNOLOGY RESEARCH. 2023;2023:9393497-10
House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model
Ramos-Ramirez P; Liu J; Mogren S; Gregory J; Noreby M; Petren A; Lei Y; Olsson H; van Hage M; Kervinen J; Hellman L; Andersson C; Nilsson G; Adner M
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1151754
Analysis of human lung mast cells by single cell RNA sequencing
Ronnberg E; Ravindran A; Mazzurana L; Gong Y; Safholm J; Lorent J; Dethlefsen O; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Dahlin JS; Mjosberg J; Nilsson G
Article: NATURE COMMUNICATIONS. 2022;13(1):7483
Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function
Zhang L; Simonsen C; Zimova L; Wang K; Moparthi L; Gaudet R; Ekoff M; Nilsson G; Hellmich UA; Vlachova V; Gourdon P; Zygmunt PM
Article: JOURNAL OF LIPID RESEARCH. 2022;63(12):100310
Biosynthesis of prostaglandin 15dPGJ₂ -glutathione and 15dPGJ₂-cysteine conjugates in macrophages and mast cells via MGST3
Steinmetz-Spah J; Liu J; Singh R; Ekoff M; Boddul S; Tang X; Bergqvist F; Idborg H; Heitel P; Ronnberg E; Merk D; Wermeling F; Haeggstrom JZ; Nilsson G; Steinhilber D; Larsson K; Korotkova M; Jakobsson P-J
Article: SCIENTIFIC REPORTS. 2022;12(1):18924
Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models
Liu J; Nie M; Dong C; Safholm J; Pejler G; Nilsson G; Adner M
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(9):2677-2687
Activation of succinate receptor 1 boosts human mast cell reactivity and allergic bronchoconstriction
Tang X; Ronnberg E; Safholm J; Thulasingam M; Trauelsen M; Schwartz TW; Wheelock CE; Dahlen S-E; Nilsson G; Haeggstrom JZ
Article: BLOOD ADVANCES. 2022;6(15):4439-4449
Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors
Wu C; Boey D; Bril O; Grootens J; Vijayabaskar MS; Sorini C; Ekoff M; Wilson NK; Ungerstedt JS; Nilsson G; Dahlin JS
Article: JOURNAL OF AUTOIMMUNITY. 2022;131:102857
Modulating T-cell activation with antisense oligonucleotides targeting lymphocyte cytosolic protein 2
Iyer VS; Boddul SV; Johnsson A-K; Raposo B; Sharma RK; Shen Y; Kasza Z; Lim KW; Chemin K; Nilsson G; Malmstrom V; Phan AT; Wermeling F
Article: HEMASPHERE. 2021;5(11):e646
Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal
Valent P; Akin C; Hartmann K; Alvarez-Twose I; Brockow K; Hermine O; Niedoszytko M; Schwaab J; Lyons JJ; Carter MC; Elberink HO; Butterfield JH; George TI; Greiner G; Ustun C; Bonadonna P; Sotlar K; Nilsson G; Jawhar M; Siebenhaar F; Broesby-Olsen S; Yavuz S; Zanotti R; Lange M; Nedoszytko B; Hoermann G; Castells M; Radia DH; Munoz-Gonzalez JI; Sperr WR; Triggiani M; Kluin-Nelemans HC; Galli SJ; Schwartz LB; Reiter A; Orfao A; Gotlib J; Arock M; Horny H-P; Metcalfe DD
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(3):889-894
Distinct plasma biomarkers confirm the diagnosis of mastocytosis and identify increased risk of anaphylaxis
Gulen T; Teufelberger A; Ekoff M; Westerberg CM; Lyberg K; Dahlen S-E; Dahlen B; Nilsson G
Article: CELL RESEARCH. 2021;31(5):554-568
Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing
Mazzurana L; Czarnewski P; Jonsson V; Wigge L; Ringner M; Williams TC; Ravindran A; Bjorklund AK; Safholm J; Nilsson G; Dahlen S-E; Orre A-C; Al-Ameri M; Hoog C; Hedin C; Szczegielniak S; Almer S; Mjosberg J
Article: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2021;1866(5):158886
COX-1 dependent biosynthesis of 15-hydroxyeicosatetraenoic acid in human mast cells
Johnsson A-K; Ronnberg E; Fuchs D; Kolmert J; Safholm J; Claesson H-E; Hamberg M; Wheelock CE; Nilsson G; Dahlen S-E
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(4):594-603
Selective inhibition of prostaglandin D₂ biosynthesis in human mast cells to overcome need for multiple receptor antagonists: Biochemical consequences
Johnsson A-K; Choi J-H; Ronnberg E; Fuchs D; Kolmert J; Hamberg M; Dahlen B; Wheelock CE; Dahlen S-E; Nilsson G
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2021;106(2):290-293
Graft-versus-mastocytosis effect after donor lymphocyte infusion: Proof of principle
Hagglund H; Yavuz AS; Dreimane A; Malm C; Sundin A; Sander B; Nilsson G
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:804812
Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity
Ronnberg E; Boey DZH; Ravindran A; Safholm J; Orre A-C; Al-Ameri M; Adner M; Dahlen S-E; Dahlin JS; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2020;50(10):1184-1195
A new house dust mite-driven and mast cell-activated model of asthma in the guinea pig
Ramos-Ramirez P; Noreby M; Liu J; Ji J; Abdillahi SM; Olsson H; Dahlen S-E; Nilsson G; Adner M
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:559589
Amelioration of Compound 48/80-Mediated Itch and LL-37-Induced Inflammation by a Single-Stranded Oligonucleotide
Dondalska A; Ronnberg E; Ma H; Palsson SA; Magnusdottir E; Gao T; Adam L; Lerner EA; Nilsson G; Lagerstrom M; Spetz A-L
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;75(1):211-214
CD203c distinguishes the erythroid and mast cell-basophil differentiation trajectories among human FcεRI⁺ bone marrow progenitors
Grootens J; Ungerstedt JS; Wu C; Levedahl KH; Nilsson G; Dahlin JS
Article: CELLS. 2019;8(11):1372
Wnt-3a Induces Cytokine Release in Human Mast Cells
Tebroke J; Lieverse OE; Saefholm S; Schulte G; Nilsson G; Roennberg E
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2190-2201.e9
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid
Morita H; Kubo T; Ruckert B; Ravindran A; Soyka MB; Rinaldi AO; Sugita K; Wawrzyniak M; Wawrzyniak P; Motomura K; Tamari M; Orimo K; Okada N; Arae K; Saito K; Altunbulakli C; Castro-Giner F; Tan G; Neumann A; Sudo K; O'Mahony L; Honda K; Nakae S; Saito H; Mjosberg J; Nilsson G; Matsumoto K; Akdis M; Akdis CA
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2202-2214.e5
Cytokine-induced endogenous production of prostaglandin D₂ is essential for human group 2 innate lymphoid cell activation
Maric J; Ravindran A; Mazzurana L; Van Acker A; Rao A; Kokkinou E; Ekoff M; Thomas D; Fauland A; Nilsson G; Wheelock CE; Dahlen S-E; Ferreiros N; Geisslinger G; Friberg D; Heinemann A; Konya V; Mjosberg J
Article: EBIOMEDICINE. 2019;43:150-158
Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis
Grootens J; Ungerstedt JS; Ekoff M; Ronnberg E; Klimkowska M; Amini R-M; Arock M; Soderlund S; Mattsson M; Nilsson G; Dahlin JS
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2019;9:289
Cryptococcus neoformans Induces MCP-1 Release and Delays the Death of Human Mast Cells
Lopes JP; Stylianou M; Backman E; Holmberg S; Ekoff M; Nilsson G; Urban CF
Article: AMERICAN JOURNAL OF PHYSIOLOGY - LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2018;314(3):L484-L492
Mast cell-dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma
Nilsson AMZ; Lei Y; Adner M; Nilsson GP
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2193
An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells
Ravindran A; Ronnberg E; Dahlin JS; Mazzurana L; Safholm J; Orre A-C; Al-Ameri M; Peachell P; Adner M; Dahlen S-E; Mjosberg J; Nilsson G
Article: JOURNAL OF NEUROTRAUMA. 2017;34(22):3173-3182
Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury
Wicher G; Wallenquist U; Lei Y; Enoksson M; Li X; Fuchs B; Abu Hamdeh S; Marklund N; Hillered L; Nilsson G; Forsberg-Nilsson K
Article: BLOOD. 2017;130(16):1785-1794
KIT signaling is dispensable for human mast cell progenitor development
Dahlin JS; Ekoff M; Grootens J; Lof L; Amini R-M; Hagberg H; Ungerstedt JS; Olsson-Stromberg U; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: IN PRACTICE. 2017;5(5):1248-1255
Risk Factor Analysis of Anaphylactic Reactions in Patients With Systemic Mastocytosis
Gulen T; Ljung C; Nilsson G; Akin C
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(7):909-917
Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis
Gulen T; Westerberg CM; Lyberg K; Ekoff M; Kolmert J; Bood J; Ohd J; James A; Dahlen S-E; Nilsson G; Dahlen B
Article: SCIENTIFIC REPORTS. 2017;7(1):4219
Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma
Sjoberg LC; Nilsson AZ; Lei Y; Gregory JA; Adner M; Nilsson GP
Article: IMMUNOBIOLOGY. 2017;222(4):647-650
Curdlan induces selective mast cell degranulation without concomitant release of LTC₄, IL-6 or CCL2
Barbosa-Lorenzi VC; Peyda S; Scheynius A; Nilsson G; Lunderius-Andersson C
Article: ONCOTARGET. 2017;8(6):9647-9659
Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis
Lyberg K; Ali HA; Grootens J; Kjellander M; Tirfing M; Arock M; Hagglund H; Nilsson G; Ungerstedt J
Article: ACTA DERMATO-VENEREOLOGICA. 2016;96(5):602-612
Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus
Broesby-Olsen S; Dybedal I; Gulen T; Kristensen TK; Moller MB; Ackermann L; Saaf M; Karlsson M; Agertoft L; Brixen K; Hermann P; Stylianou E; Mortz CG; Torfing T; Havelund T; Sander B; Bergstrom A; Bendix M; Garvey LH; Weis Bjerrum O; Valent P; Bindslev-Jensen C; Nilsson G; Vestergaard H; Hagglund H
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2016;778:68-76
IL-33 and Thymic Stromal Lymphopoietin in mast cell functions
Saluja R; Zoltowska A; Ketelaar ME; Nilsson G
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2016;14(3):606-618
Tetraspanin CD151 and integrin 61 mediate platelet-enhanced endothelial colony forming cell angiogenesis
Huang Z; Miao X; Patarroyo M; Nilsson GP; Pernow J; Li N
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2016;46(3):479-490
The interleukin-33 receptor ST2 is important for the development of peripheral airway hyperresponsiveness and inflammation in a house dust mite mouse model of asthma
Zoltowska AM; Lei Y; Fuchs B; Rask C; Adner M; Nilsson GP
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;137(1):35-45
Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology
Hartmann K; Escribano L; Grattan C; Brockow K; Carter MC; Alvarez-Twose I; Matito A; Broesby-Olsen S; Siebenhaar F; Lange M; Niedoszytko M; Castells M; Oude Elberink JNG; Bonadonna P; Zanotti R; Hornick JL; Torrelo A; Grabbe J; Rabenhorst A; Nedoszytko B; Butterfield JH; Gotlib J; Reiter A; Radia D; Hermine O; Sotlar K; George TI; Kristensen TK; Kluin-Nelemans HC; Yavuz S; Hagglund H; Sperr WR; Schwartz LB; Triggiani M; Maurer M; Nilsson G; Horny H-P; Arock M; Orfao A; Metcalfe DD; Akin C; Valent P
Article: SCIENTIFIC REPORTS. 2015;5:12287
Opportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells
Lopes JP; Stylianou M; Nilsson G; Urban CF
Article: ACTA DERMATO-VENEREOLOGICA. 2015;95(5):536-541
Experimentally Induced Psoriatic Lesions Associate with Rapid but Transient Decrease in Interleukin-33 Immunostaining in Epidermis
Suttle M-M; Enoksson M; Zoltowska A; Chatterjee M; Nilsson G; Harvima IT
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;70(5):514-521
Interleukin-33 exacerbates allergic bronchoconstriction in the mice via activation of mast cells
Sjoberg LC; Gregory JA; Dahlen S-E; Nilsson GP; Adner M
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13(3):465-476
PAR1-stimulated platelet releasate promotes angiogenic activities of endothelial progenitor cells more potently than PAR4-stimulated platelet releasate
Huang Z; Miao X; Luan Y; Zhu L; Kong F; Lu Q; Pernow J; Nilsson G; Li N
Article: JOURNAL OF IMMUNOLOGY. 2015;194(3):1316-1322
Knockdown of the Antiapoptotic Bcl-2 Family Member A1/Bfl-1 Protects Mice from Anaphylaxis
Ottina E; Lyberg K; Sochalska M; Villunger A; Nilsson GP
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2015;70(2):161-170
Eotaxin-3 (CCL26) exerts innate host defense activities that are modulated by mast cell proteases
Gela A; Kasetty G; Jovic S; Ekoff M; Nilsson G; Morgelin M; Kjellstrom S; Pease JE; Schmidtchen A; Egesten A
Article: METHODS IN MOLECULAR BIOLOGY. 2015;1220:257-267
Regulation of mast cell survival and apoptosis.
Westerberg CM; Ekoff M; Nilsson G
Article: PLOS ONE. 2015;10(7):e0133774
Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma
Lei Y; Boinapally V; Zoltowska A; Adner M; Hellman L; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(3):530-544
Molecular targets on mast cells and basophils for novel therapies
Harvima IT; Levi-Schaffer F; Draber P; Friedman S; Polakovicova I; Gibbs BF; Blank U; Nilsson G; Maurer M
Article: ACTA DERMATO-VENEREOLOGICA. 2014;94(5):583-584
Increased Risk of Malignant Melanoma in Patients with Systemic Mastocytosis?
Hagglund H; Sander B; Gulen T; Lindelof B; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(9):1179-1187
The presence of mast cell clonality in patients with unexplained anaphylaxis
Gulen T; Hagglund H; Sander B; Dahlen B; Nilsson G
Article: MEDICAL ONCOLOGY. 2014;31(8):123
Analysis of V600E BRAF and D816V KIT mutations in systemic mastocytosis
Hagglund H; Sander B; Ahmadi A; Gulen T; Nilsson G
Article: MOLECULAR ONCOLOGY. 2014;8(1):50-58
Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner
Polajeva J; Bergstrom T; Edqvist P-H; Lundequist A; Sjosten A; Nilsson G; Smits A; Bergqvist M; Ponten F; Westermark B; Pejler G; Nilsson KF; Tchougounova E
Article: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2014;406(6):1751-1762
A quantitative LC/MS method targeting urinary 1-methyl-4-imidazoleacetic acid for safety monitoring of the global histamine turnover in clinical studies
Kolmert J; Forngren B; Lindberg J; Ohd J; Aberg KM; Nilsson G; Moritz T; Nordstrom A
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(1):121-129
High prevalence of anaphylaxis in patients with systemic mastocytosis - a single-centre experience
Gulen T; Hagglund H; Dahlen B; Nilsson G
Article: CLINICAL SCIENCE. 2013;125(11-12):533-542
Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma
Riley JP; Fuchs B; Sjoberg L; Nilsson GP; Karlsson L; Dahlen S-E; Rao NL; Adner M
Article: NEUROSCIENCE LETTERS. 2013;555:171-176
Developmental expression of IL-33 in the mouse brain
Wicher G; Husic E; Nilsson G; Forsberg-Nilsson K
Article: CLINICAL AND TRANSLATIONAL ALLERGY. 2013;3(1):22
The significance of diagnosing associated clonal mast cell diseases in patients with venom-induced anaphylaxis and the role of bone marrow investigation.
Gülen T; Dahlén B; Sander B; Hägglund H; Nilsson G
Article: BLOOD. 2013;121(3):530-536
Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent
Enoksson M; Moller-Westerberg C; Wicher G; Fallon PG; Forsberg-Nilsson K; Lunderius-Andersson C; Nilsson G
Article: JOURNAL OF LIPID RESEARCH. 2013;54(1):116-126
Lipid mediator metabolic profiling demonstrates differences in eicosanoid patterns in two phenotypically distinct mast cell populations
Lundstrom SL; Saluja R; Adner M; Haeggstrom JZ; Nilsson G; Wheelock CE
Article: AMERICAN JOURNAL OF PHYSIOLOGY - LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;303(12):l1027-l1036
Mast cell engraftment of the peripheral lung enhances airway hyperresponsiveness in a mouse asthma model
Fuchs B; Sjoberg L; Westerberg CM; Ekoff M; Swedin L; Dahlen S-E; Adner M; Nilsson GP
Article: MEDICAL ONCOLOGY. 2012;29(5):3540-3546
Systemic mastocytosis: progressive evolution of an occult disease into fatal mast cell leukemia: unique findings on an unusual hematological neoplasm
Gulen T; Sander B; Nilsson G; Palmblad J; Sotlar K; Horny H-P; Hagglund H
Article: CELL DEATH AND DISEASE. 2012;3(11):e417
Proteasome inhibition upregulates Bim and induces caspase-3-dependent apoptosis in human mast cells expressing the Kit D816V mutation
Westerberg CM; Hagglund H; Nilsson G
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2012;382(1-2):160-166
Differentiation of mast cell subpopulations from mouse embryonic stem cells
Westerberg CM; Ulleras E; Nilsson G
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2012;169(3):311-319
Experimentally induced psoriatic lesion associates with interleukin (IL)-6 in mast cells and appearance of dermal cells expressing IL-33 and IL-6 receptor
Suttle M-M; Nilsson G; Snellman E; Harvima IT
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2012;67(7):958-961
Corticosteroid treatment selectively decreases mast cells in the smooth muscle and epithelium of asthmatic bronchi
James A; Gyllfors P; Henriksson E; Dahlen SE; Adner M; Nilsson G; Dahlen B
Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2012;8(3):235-241
Stress, the neuroendocrine system and mast cells: current understanding of their role in psoriasis
Harvima IT; Nilsson G
Article: PLOS ONE. 2012;7(10):e48308
Human Cord Blood Derived Immature Basophils Show Dual Characteristics, Expressing Both Basophil and Eosinophil Associated Proteins
Grundstrom J; Reimer JM; Magnusson SE; Nilsson G; Wernersson S; Hellman L
Article: PLOS ONE. 2012;7(8):e43547
FcεR₁-Mediated Mast Cell Reactivity Is Amplified through Prolonged Toll-Like Receptor-Ligand Treatment
Saluja R; Delin I; Nilsson GP; Adner M
Article: PLOS ONE. 2012;7(6):e39117
Anti-Apoptotic Bfl-1 Is the Major Effector in Activation-Induced Human Mast Cell Survival
Ekoff M; Lyberg K; Krajewska M; Arvidsson M; Rak S; Reed JC; Harvima I; Nilsson G
Article: BLOOD. 2011;117(14):3907-3911
Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli
Chatterjee M; Huang Z; Zhang W; Jiang L; Hultenby K; Zhu L; Hu H; Nilsson GP; Li N
Article: AMERICAN JOURNAL OF PATHOLOGY. 2011;178(4):1676-1688
Expression of Prostaglandin E Synthases in Periodontitis Immunolocalization and Cellular Regulation
Bage T; Kats A; Lopez BS; Morgan G; Nilsson G; Burt I; Korotkova M; Corbett L; Knox AJ; Pino L; Jakobsson P-J; Modeer T; Yucel-Lindberg T
Article: IMMUNITY. 2011;34(2):258-268
Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo
Oschatz C; Maas C; Lecher B; Jansen T; Bjorkqvist J; Tradler T; Sedlmeier R; Burfeind P; Cichon S; Hammerschmidt S; Mueller-Esterl W; Wuillemin WA; Nilsson G; Renne T
Article: JOURNAL OF IMMUNOLOGY. 2011;186(4):2523-2528
Mast Cells as Sensors of Cell Injury through IL-33 Recognition
Enoksson M; Lyberg K; Moller-Westerberg C; Fallon PG; Nilsson G; Lunderius-Andersson C
Article: PLOS ONE. 2011;6(7):e22202
The Expression of BAFF, APRIL and TWEAK Is Altered in Eczema Skin but Not in the Circulation of Atopic and Seborrheic Eczema Patients
Chen Y; Enoksson SL; Johansson C; Karlsson MA; Lundeberg L; Nilsson G; Scheynius A; Karlsson MCI
Article: JOURNAL OF INNATE IMMUNITY. 2011;3(2):142-149
Human Cord Blood-Derived Mast Cells Are Activated by the Nod1 Agonist M-TriDAP to Release Pro-Inflammatory Cytokines and Chemokines
Enoksson M; Ejendal KFK; McAlpine S; Nilsson G; Lunderius-Andersson C
Article: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2011;716:47-60
MAST CELL APOPTOSIS AND SURVIVAL
Ekoff M; Nilsson G
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2011;66(1):110-119
Mast cells generated from patients with atopic eczema have enhanced levels of granule mediators and an impaired Dectin-1 expression
Ribbing C; Engblom C; Lappalainen J; Lindstedt K; Kovanen PT; Karlsson MA; Lundeberg L; Johansson C; Nilsson G; Lunderius-Andersson C; Scheynius A
Article: PLOS ONE. 2010;5(8):e12360
Mast Cell Survival and Mediator Secretion in Response to Hypoxia
Gulliksson M; Carvalho RFS; Ulleras E; Nilsson G
Article: JOURNAL OF IMMUNOLOGY. 2010;185(4):2555-2562
The BH3-Mimetic ABT-737 Induces Mast Cell Apoptosis In Vitro and In Vivo: Potential for Therapeutics
Karlberg M; Ekoff M; Huang DCS; Mustonen P; Harvima IT; Nilsson G
Article: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2010;92(1-4):44-53
Prostaglandin modulation of airway inflammation and hyperresponsiveness in mice sensitized without adjuvant
Swedin L; Ellis R; Neimert-Andersson T; Ryrfeldt A; Nilsson G; Inman M; Dahlen S-E; Adner M
Article: CELL DEATH AND DISEASE. 2010;1(5):e43
Pro-apoptotic Bax is the major and Bak an auxiliary effector in cytokine deprivation-induced mast cell apoptosis
Karlberg M; Ekoff M; Labi V; Strasser A; Huang D; Nilsson G
Article: EXPERIMENTAL DERMATOLOGY. 2010;19(2):117-122
Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation
Carvalho RFDS; Nilsson G; Harvima IT
Article: JOURNAL OF IMMUNOLOGY. 2009;183(7):4657-4665
Human Mast Cells Adhere to and Migrate on Epithelial and Vascular Basement Membrane Laminins LM-332 and LM-511 via α₃β₁ Integrin
Sime W; Lunderius-Andersson C; Enoksson M; Rousselle P; Tryggvason K; Nilsson G; Harvima I; Patarroyo M
Article: JOURNAL OF IMMUNOLOGY. 2009;182(7):4208-4216
TLR2/MyD88-Dependent and -Independent Activation of Mast Cell IgE Responses by the Skin Commensal Yeast Malassezia sympodialis
Selander C; Engblom C; Nilsson G; Scheynius A; Andersson CL
Article: JOURNAL OF RHEUMATOLOGY. 2009;36(3):501-507
CD153 in Rheumatoid Arthritis: Detection of a Soluble Form in Serum and Synovial Fluid, and Expression by Mast Cells in the Rheumatic Synovium
Carvalho RFS; Ulfgren A-K; Engstrom M; Af Klint E; Nilsson G
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2008;28(3):250-255
FcγRI-Mediated activation of human mast cells promotes survival and induction of the pro-survival gene bfl-1
Karlberg M; Xiang Z; Nilsson G
Article: BLOOD. 2008;111(6):3081-3089
NFAT but not NF-κB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells
Ulleras E; Karlberg M; Westerberg CM; Alfredsson J; Gerondakis S; Strasser A; Nilsson G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):53-56
Expression of mast cell tryptases in hodgkin and reed-sternberg (HRS) cells
Carvalho RFS; Mahshid Y; Claesson H-E; Glimelius I; Fischer M; Nilsson G
Article: CANCER RESEARCH. 2007;67(24):11528-11535
Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice
Brideau G; Makinen MJ; Elamaa H; Tu H; Nilsson G; Alitalo K; Pihlajaniemi T; Heljasvaara R
Article: BLOOD. 2007;110(9):3209-3217
The BH3-only protein Puma plays an essential role in cytokine deprivation-induced apoptosis of mast cells
Ekoff M; Kaufmann T; Engstrom M; Motoyama N; Villunger A; Jonsson J-I; Strasser A; Nilsson G
Article: HEMATOLOGY/ONCOLOGY CLINICS OF NORTH AMERICA. 2007;21(5):805-823
The potential role of innate immunity in the pathogenesis of Hodgkin's lymphoma
Enblad G; Molin D; Glimelius I; Fischer M; Nilsson G
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2007;1771(9):1156-1165
Expression of 15-lipoxygenase type-1 in human mast cells
Gulliksson M; Brunnstrom A; Johannesson M; Backman L; Nilsson G; Harvima I; Dahlen B; Kumlin M; Claesson H-E
Article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2007;56(9):1407-1415
Increase in CD30 ligand/CD153 and TNF-α expressing mast cells in basal cell carcinoma
Diaconu N-C; Kaminska R; Naukkarinen A; Harvima RJ; Nilsson G; Harvima IT
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2007;138(1):68-71
Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma
Hedstrom G; Berglund M; Molin D; Fischer M; Nilsson G; Thunberg U; Book M; Sundstrom C; Rosenquist R; Roos G; Erlanson M; Amini R-M; Enblad G
Article: JOURNAL OF IMMUNOLOGY. 2007;178(7):4177-4183
FcεRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells
Ekoff M; Strasser A; Nilsson G
Article: EXPERIMENTAL HEMATOLOGY. 2007;35(3):385-393
Bcl-2 and Bcl-XL are indispensable for the late phase of mast cell development from mouse embryonic stem cells
Moeller C; Karlberg M; Abrink M; Nakayama KI; Motoyama N; Nilsson G
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;61(12):1473-1479
Release of prostaglandin D₂ and leukotriene C₄ in response to hyperosmolar stimulation of mast cells
Gulliksson M; Palmberg L; Nilsson G; Ahlstedt S; Kumlin M
Article: JOURNAL OF CLINICAL INVESTIGATION. 2006;116(10):2748-2756
Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion
Fischer M; Harvima IT; Carvalho RFS; Moller C; Naukkarinen A; Enblad G; Nilsson G
Article: ALLERGY, ASTHMA & CLINICAL IMMUNOLOGY. 2006;2(3):87-97
Coaggregation of FcepsilonRI with FcgammaRIIB Inhibits Degranulation but Not Induction of Bcl-2 Family Members A1 and Bim in Mast Cells.
Ekoff M; Möller C; Xiang Z; Nilsson G
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;61(9):1063-1070
Isolation of transcriptionally active umbilical cord blood-derived basophils expressing FcεRI, HLA-DR and CD203c
Reimer JM; Magnusson S; Juremalm M; Nilsson G; Hellman L; Wernersson S
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;61(9):1040-1046
IgE-receptor activation induces survival and Bfl-1 expression in human mast cells but not basophils
Xiang Z; Moller C; Nilsson G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(4):282-289
FcγRIII-expressing macrophages are essential for development of collagen-induced arthritis
Andrén M; Xiang Z; Nilsson G; Kleinau S
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2006;76(4):278-283
IL-9 expression contributes to the cellular composition in Hodgkin lymphoma
Glimelius I; Edström A; Amini RM; Fischer M; Nilsson G; Sundström C; Enblad G; Molin D
Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2006;141(2):168-171
Readministration of IgE is required for repeated passive cutaneous anaphylaxis in mice
Xiang Z; Moller C; Nilsson G
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;63(1):1-6
IgE-receptor activation of mast cells regulates phosphorylation and expression of forkhead and bcl-2 family members
Alfredsson J; Möller C; Nilsson G
Article: BLOOD. 2005;106(4):1330-1336
Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim
Möller C; Alfredsson J; Engström M; Wootz H; Xiang Z; Lennartsson J; Jönsson JI; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2005;35(6):708-712
CCL17 and CCL22 attenuate CCL5-induced mast cell migration
Juremalm M; Olsson N; Nilsson G
Article: CELL DEATH AND DIFFERENTIATION. 2005;12(2):136-144
Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-X_L upon IgE-receptor activation
Alfredsson J; Puthalakath H; Martin H; Strasser A; Nilsson G
Article: TOXICOLOGY. 2005;206(2):257-272
Detection of immunotoxicity using T-cell based cytokine reporter cell lines ("Cell Chip")
Ringerike T; Ullerås E; Völker R; Verlaan B; Eikeset A; Trzaska D; Adamczewska V; Olszewski M; Walczak-Drzewiecka A; Arkusz J; van Loveren H; Nilsson G; Lovik M; Dastych J; Vandebriel RJ
Article: TOXICOLOGY. 2005;206(2):245-256
Development of the "Cell Chip":: a new in vitro alternative technique for immunotoxicity testing
Ullerås E; Trzaska D; Arkusz J; Ringerike T; Adamczewskaa V; Olszewski M; Wyczólkowska J; Walczak-Drzewlecka A; Al-Nedawi K; Nilsson G; Bialek-Wyrzykowska U; Stepnik M; Van Loveren H; Vandebriel RJ; Lovik M; Rydzynski K; Dastych J
Article: CELLULAR IMMUNOLOGY. 2004;230(2):65-80
Alterations in mast cell function and survival following in vitro infection with human immunodeficiency viruses-1 through CXCR4
Taub DD; Mikovits JA; Nilsson G; Schaffer EM; Key ML; Petrow-Sadowski C; Ruscetti FW
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2004;59(3):267-272
Regulation of mast cell migration by T_H1 and T_H2 cytokines:: Identification of tumour necrosis factor-α and interleukin-4 as mast cell chemotaxins
Olsson N; Taub DD; Nilsson G
Article: LEUKEMIA. 2003;17(12):2513-2516
Increased serum levels of interleukin-9 correlate to negative prognostic factors in Hodgkin's lymphoma
Fischer M; Bijman M; Molin D; Cormont F; Uyttenhove C; van Snick J; Sundström C; Enblad G; Nilsson G
Article: INTERNATIONAL JOURNAL OF CANCER. 2003;107(2):197-201
Expression of CCL5/rantes by Hodgkin and reed-sternberg cells and its possible role in the recruitment of mast cells into lymphomatous tissue
Fischer M; Juremalm M; Olsson N; Backlin C; Sundström C; Nilsson K; Enblad G; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2003;33(8):1135-1140
Activation of mast cells by immunoglobulin E-receptor cross-linkage, but not through adenosine receptors, induces A1 expression and promotes survival
Möller C; Xiang Z; Nilsson G
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2003;88(4):1445-1452
Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells
Sköldberg F; Portela-Gomes GM; Grimelius L; Nilsson G; Perheentupa J; Betterle C; Husebye ES; Gustafsson J; Rönnblom A; Rorsman F; Kämpe O
Article: EXPERIMENTAL DERMATOLOGY. 2003;12(1):53-60
Mast cell survival and apoptosis in organ-cultured human skin
Kivinen PK; Nilsson G; Naukkarinen A; Harvima IT
Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2003;120(2):239-245
Retinoic acid inhibits in vitro development of mast cells but has no marked effect on mature human skin tryptase- and chymase-positive mast cells
Hjertson M; Kivinen PK; Dimberg L; Nilsson K; Harvima IT; Nilsson G
Article: LEUKEMIA. 2003;17(1):203-210
Expression and function of chemokine receptors in human multiple myeloma
Möller C; Strömberg T; Juremalm M; Nilsson K; Nilsson G
Article: IMMUNOLOGY. 2003;108(1):89-97
Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene
Sundström M; Vliagoftis H; Karlberg P; Butterfield JH; Nilsson K; Metcalfe DD; Nilsson G
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2002;119(1):122-124
Mast cell infiltration correlates with poor prognosis in Hodgkin's lymphoma
Molin D; Edström A; Glimelius I; Glimelius B; Nilsson G; Sundström C; Enblad G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;297(3):480-485
Selective CCL5/RANTES-induced mast cell migration through interactions with chemokine receptors CCR1 and CCR4
Juremalm M; Olsson N; Nilsson G
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2002;1583(1):53-62
Human mast cells express two leukotriene C₄ synthase isoenzymes and the CysLT₁ receptor
Sjöström M; Jakobsson PJ; Juremalm M; Ahmed A; Nilsson G; Macchia L; Haeggström JZ
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2001;194(11):1561-1569
Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation
Xiang Z; Ahmed AA; Möller C; Nakayama K; Hatakeyama S; Nilsson G
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(11):3240-3247
Distinct and regulated expression of Notch receptors in hematopoietic lineages and during myeloid differentiation
Jönsson JI; Xiang Z; Pettersson M; Lardelli M; Nilsson G
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2001;114(3):616-623
Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease
Molin D; Fischer M; Xiang Z; Larsson U; Harvima I; Venge P; Nilsson K; Sundström C; Enblad G; Nilsson G
Article: BLOOD. 2001;98(4):1195-1199
The Kit-activating mutation D816V enhances stem cell factor-dependent chemotaxis
Taylor ML; Dastych J; Sehgal D; Sundstrom M; Nilsson G; Akin C; Mage RG; Metcalfe DD
Article: CELLULAR SIGNALLING. 2001;13(7):483-490
Transforming growth factor-β-mediated mast cell migration depends on mitogen-activated protein kinase activity
Olsson N; Piek E; Sundström M; ten Dijke P; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2001;108(1):116-121
IgE-mediated mast cell degranulation and recovery monitored by time-lapse photography
Zou X; Block M; Löfman C; Nilsson G
Article: EXPERIMENTAL CELL RESEARCH. 2001;267(1):144-151
Stem cell factor-induced migration of mast cells requires p38 mitogen-activated protein kinase activity
Sundström M; Alfredsson J; Olsson N; Nilsson G
Article: EXPERIMENTAL DERMATOLOGY. 2001;10(3):184-192
Inhibition of keratinocyte growth in cell culture and whole skin culture by mast cell mediators
Huttunen M; Hyttinen M; Nilsson G; Butterfield JH; Horsmanheimo M; Harvima IT
Article: ANNALS OF THE RHEUMATIC DISEASES. 2001;60(3):187-193
Demonstration of mast cell chemotactic activity in synovial fluid from rheumatoid patients
Olsson N; Ulfgren AK; Nilsson G
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(12):3396-3402
Murine mast cell fines as indicators of early events in mast cell and basophil development
Lunderius C; Xiang Z; Nilsson G; Hellman L
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(12):3614-3622
The chemokine receptor CXCR4 is expressed within the mast cell lineage and its ligand stromal cell-derived factor-1α acts as a mast cell chemotaxin
Juremalm M; Hjertson M; Olsson N; Harvima I; Nilsson K; Nilsson G
Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2000;30(10):1379-1386
IgE receptor-mediated release of nerve growth factor by mast cells
Xiang Z; Nilsson G
Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2000;67(3):350-356
Human mast cell migration in response to members of the transforming growth factor-β family
Olsson N; Piek E; ten Dijke P; Nilsson G
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(3):455-461
Demonstration of mast cell chemotactic activity in bronchoalveolar lavage fluid collected from asthmatic patients before and during pollen season
Olsson N; Rak S; Nilsson G
Article: IMMUNOLOGY. 2000;99(2):314-319
Demonstration that platelet-activating factor is capable of activating mast cells and inducing a chemotactic response
Nilsson G; Metcalfe DD; Taub DD
Article: BLOOD. 1999;93(9):2791-2797
Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/interleukin-8RB
Nilsson G; Mikovits JA; Metcalfe DD; Taub DD
Article: BRITISH JOURNAL OF HAEMATOLOGY. 1999;104(3):516-522
The potential of human mast cell progenitors to differentiate into mature mast cells remains after prolonged culture with flt3 ligand, interleukin-3 or granulocyte-macrophage colony stimulating factor
Hjertson M; Sundström C; Nilsson K; Nilsson G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;254(1):143-146
Serum amyloid a induces chemotaxis of human mast cells by activating a pertussis toxin-sensitive signal transduction pathway
Olsson N; Siegbahn A; Nilsson G
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 1998;53(9):874-879
Demonstration of mast-cell chemotactic activity in nasal lavage fluid: characterization of one chemotaxin as c-kit ligand, stem cell factor
Nilsson G; Hjertson M; Andersson M; Greiff L; Svensson C; Nilsson K; Siegbahn A
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1997;27(9):2295-2301
Human mast cells express functional TrkA and are a source of nerve growth factor
Nilsson G; ForsbergNilsson K; Xiang Z; Hallbook F; Nilsson K; Metcalfe DD
Article: LEUKEMIA. 1997;11(8):1298-1304
Interleukin-15 plus thioredoxin induce DNA synthesis in B-chronic lymphocytic leukemia cells but not in normal B cells
Soderberg O; Christiansen I; Nilsson G; Carlsson M; Nilsson K
Article: JOURNAL OF PATHOLOGY. 1996;180(4):434-440
Alterations in mast cell proteinases and protease inhibitors in the progress of cutaneous herpes zoster infection
Kaminska R; Harvima IT; Naukkarinen A; Nilsson G; Horsmanheimo M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(3):267-272
The fibroblast mitogenic activity released from human basophilic cell line KU812 is separate from tryptase and PDGF expression
ForsbergNilsson K; Dunder U; Nilsson K; Schwartz LB; Nilsson G
Article: JOURNAL OF IMMUNOLOGY. 1996;157(4):1693-1698
C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway
Nilsson G; Johnell M; Hammer CH; Tiffany HL; Nilsson K; Metcalfe DD; Siegbahn A; Murphy PM
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1996;44(1):54-61
Characterization of a human basophil-like cell line (LAMA-84)
Blom T; Nilsson G; Sundstrom C; Nilsson K; Hellman L
Article: IMMUNOLOGY. 1996;88(2):308-314
Stem cell factor-dependent human cord blood derived mast cells express alpha- and beta-tryptase, heparin and chondroitin sulphate
Nilsson G; Blom T; Harvima I; KuscheGullberg M; Nilsson K; Hellman L
Article: EXPERIMENTAL HEMATOLOGY. 1996;24(6):748-754
Stem cell factor, but not flt3 ligand, induces differentiation and activation of human mast cells
Hjertson M; Sundstrom C; Lyman SD; Nilsson K; Nilsson G
Article: ALLERGY AND ASTHMA PROCEEDINGS. 1996;17(2):59-63
Contemporary issues in mast cell biology
Nilsson G; Metcalfe DD
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1995;42(1):76-81
CONSTITUTIVE AND INDUCIBLE CYTOKINE MESSENGER-RNA EXPRESSION IN THE HUMAN MAST-CELL LINE HMC-1
NILSSON G; SVENSSON V; NILSSON K
Article: IMMUNOLOGY. 1995;84(1):72-78
DEXAMETHASONE INHIBITS THE DEVELOPMENT OF MAST-CELLS FROM DISPERSED HUMAN FETAL LIVER-CELLS CULTURED IN THE PRESENCE OF RECOMBINANT HUMAN STEM-CELL FACTOR
IRANI AA; NILSSON G; ASHMAN LK; SCHWARTZ LB
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Letter: BLOOD ADVANCES. 2024;8(15):3941-3945
CRISPR/Cas9-mediated gene disruption determines the roles of MITF and CITED2 in human mast cell differentiation
Mo J; Wermeling F; Nilsson G; Dahlin JS
Editorial comment: BLOOD. 2024;143(11):945-947
Systemic mastocytosis or survivin
Dahlin JS; Nilsson G
Editorial comment: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;78(5):1395-1396
Legends of Allergy and Immunology-Dean D. Metcalfe
Akin C; Brockow K; Hartmann K; Nilsson GP
Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;150(4):785-787
Charting hematopoiesis in the single-cell omics era
Boey D; Nilsson G; Dahlin JS
Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(6):1909-1911
Mast cells derived from systemic mastocytosis exhibit an increased responsiveness to hyperosmolarity
Lyberg K; Ekoff M; Westerberg CM; Engblom C; Dahlen B; Gulen T; Nilsson G
Review: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(1):83-99
The ingenious mast cell: Contemporary insights into mast cell behavior and function
Dahlin JS; Maurer M; Metcalfe DD; Pejler G; Sagi-Eisenberg R; Nilsson G
Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;76(7):2270-2273
Distinct effects of antigen and Compound 48/80 in the guinea pig trachea
Liu J; Kolmert J; Safholm J; Johnsson A-K; Zurita J; Wheelock CE; Dahlen S-E; Nilsson G; Adner M
Review: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(6):2964
Epigenetic Changes in Neoplastic Mast Cells and Potential Impact in Mastocytosis
Reszka E; Jablonska E; Wieczorek E; Valent P; Arock M; Nilsson G; Nedoszytko B; Niedoszytko M
Review: CLINICAL SCIENCE. 2020;134(11):1219-1242
Back to the future: re-establishing guinea pig in vivo asthma models.
Adner M; Canning BJ; Meurs H; Ford W; Ramos Ramírez P; van den Berg MPM; Birrell MA; Stoffels E; Lundblad LKA; Nilsson GP; Olsson HK; Belvisi MG; Dahlén S-E
Published conference paper: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;75(3):707-708
Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium
Hallgren J; Hellman L; Maurer M; Nilsson GP; Wernersson S; Abrink M; Pejler G
Review: THERANOSTICS. 2020;10(23):10743-10768
Mast cells as a unique hematopoietic lineage and cell system: From Paul Ehrlich's visions to precision medicine concepts
Valent P; Akin C; Hartmann K; Nilsson G; Reiter A; Hermine O; Sotlar K; Sperr WR; Escribano L; George TI; Kluin-Nelemans HC; Ustun C; Triggiani M; Brockow K; Gotlib J; Orfao A; Kovanen PT; Hadzijusufovic E; Sadovnik I; Horny H-P; Arock M; Schwartz LB; Austen KF; Metcalfe DD; Galli SJ
Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74(4):844-845
New insights into the origin of mast cells
Nilsson G; Dahlin JS
Editorial comment: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74(3):635-636
Legends of Allergy/Immunology: Gunnar Johansson
van Hage M; Nilsson GP
Review: LAKARTIDNINGEN. 2018;115:FASY
[Cutaneous mastocytosis - update and clinical guidelines].
Bergström A; Rollman O; Emtestam L; Mattson M; Hägglund H; Nilsson G; Karlsson M
Review: BLOOD ADVANCES. 2018;2(17):2273-2281
Deciphering the differentiation trajectory from hematopoietic stem cells to mast cells
Grootens J; Ungerstedt JS; Nilsson G; Dahlin JS
Review: IMMUNOLOGICAL REVIEWS. 2018;282(1):73-86
Changing the threshold-Signals and mechanisms of mast cell priming
Halova I; Ronnberg E; Draberova L; Vliagoftis H; Nilsson GP; Draber P
Review: TRENDS IN IMMUNOLOGY. 2017;38(9):657-667
Positive and Negative Signals in Mast Cell Activation
Bulfone-Paus S; Nilsson G; Draber P; Blank U; Levi-Schaffer F
Review: CANCER RESEARCH. 2017;77(6):1261-1270
Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future
Valent P; Akin C; Hartmann K; Nilsson G; Reiter A; Hermine O; Sotlar K; Sperr WR; Escribano L; George TI; Kluin-Nelemans HC; Ustun C; Triggiani M; Brockow K; Gotlib J; Orfao A; Schwartz LB; Broesby-Olsen S; Bindslev-Jensen C; Kovanen PT; Galli SJ; Austen KF; Arber DA; Horny H-P; Arock M; Metcalfe DD
Letter: LEUKEMIA. 2016;30(9):1953-1956
Detection of circulating mast cells in advanced systemic mastocytosis
Dahlin JS; Ungerstedt JS; Grootens J; Sander B; Guelen T; Haegglund H; Nilsson G
Review: JOURNAL OF INTERNAL MEDICINE. 2016;279(3):211-228
Mastocytosis: the puzzling clinical spectrum and challenging diagnostic aspects of an enigmatic disease
Gulen T; Hagglund H; Dahlen B; Nilsson G
Review: WORLD ALLERGY ORGANIZATION JOURNAL. 2016;9:7
Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
Metcalfe DD; Pawankar R; Ackerman SJ; Akin C; Clayton F; Falcone FH; Gleich GJ; Irani A-M; Johansson MW; Klion AD; Leiferman KM; Levi-Schaffer F; Nilsson G; Okayama Y; Prussin C; Schroeder JT; Schwartz LB; Simon H-U; Walls AF; Triggiani M
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):475-478
Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation
Ekoff M; Choi J-H; James A; Dahlen B; Nilsson G; Dahlen S-E
Editorial comment: THE LANCET. 2014;383(9928):1608
Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis
Gulen T; Hagglund H; Dahlen S-E; Sander B; Dahlen B; Nilsson G
Review: PULMONARY PHARMACOLOGY AND THERAPEUTICS. 2013;26(5):532-539
Insights into mast cell functions in asthma using mouse models
Lei Y; Gregory JA; Nilsson GP; Adner M
Review: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68(9):1093-1101
The history of mast cell and basophil research - some lessons learnt from the last century
Blank U; Falcone FH; Nilsson G
Editorial comment: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;68(5):553-554
Basophils unlimited
Gibbs BF; Nilsson GP
Review: WIENER KLINISCHE WOCHENSCHRIFT. 2012;124(23-24):807-814
European Competence Network on Mastocytosis (ECNM): 10-year jubilee, update, and future perspectives
Valent P; Arock M; Bonadonna P; Brockow K; Broesby-Olsen S; Escribano L; Gleixner KV; Grattan C; Hadzijusufovic E; Hagglund H; Hermine O; Horny H-P; Kluin-Nelemans HC; Maurer M; Niedoszytko M; Nedoszytko B; Nilsson G; Oude-Elberink HNG; Orfao A; Radia D; Reiter A; Siebenhaar F; Sotlar K; Sperr WR; Triggiani M; VanDoormaal JJ; Varkonyi J; Yavuz S; Hartmann K
Review: LAKARTIDNINGEN. 2012;109(9-10):474-477
[Systemic mastocytosis. Underestimated condition in patients with idiopathic anaphylaxis].
Gülen T; Gottberg L; Dahlén B; Nilsson G; Hägglund H
Review: FRONTIERS IN IMMUNOLOGY. 2012;3:82
Mast cells respond to cell injury through the recognition of IL-33
Lunderius-Andersson C; Enoksson M; Nilsson G
Review: ACTA DERMATO-VENEREOLOGICA. 2011;91(6):644-650
Mast Cells as Regulators of Skin Inflammation and Immunity
Harvima IT; Nilsson G
Review: JOURNAL OF INNATE IMMUNITY. 2011;3(2):120-130
The Effect of Bacterial, Viral and Fungal Infection on Mast Cell Reactivity in the Allergic Setting
McAlpine SM; Enoksson M; Lunderius-Andersson C; Nilsson G
Review: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. 2010;145(2):195-204
Role of mast cells and sensory nerves in skin inflammation
Harvima IT; Nilsson G; Naukkarinen A
Review: LAKARTIDNINGEN. 2008;105(46):3341-3347
[Mastocytosis--a disease with many faces. Investigation and treatment should be performed in consultation with Karolinska University Hospital].
Hägglund H; Gülen T; Sääf M; Sander B; Nilsson G
Review: ARCHIVES OF DERMATOLOGICAL RESEARCH. 2008;300(9):461-478
Is there a role for mast cells in psoriasis?
Harvima IT; Nilsson G; Suttle M-M; Naukkarinen A
Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2005;116(6):1383-1386
CC chemokine receptors CCR1 and CCR4 are expressed on airway mast cells in allergic asthma
Amin K; Janson C; Harvima I; Venge P; Nilsson G
Letter: LEUKEMIA. 2005;19(12):2360-2362
Angiogenesis and mast cells in Hodgkin lymphoma
Glimelius I; Edström A; Fischer M; Nilsson G; Sundström C; Molin D; Amini RM; Enblad G
Review: CHEMICAL IMMUNOLOGY AND ALLERGY. 2005;87:130-144
Chemokine receptor expression by mast cells.
Juremalm M; Nilsson G
Meeting abstract: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2000;105(1):s79
The activating mutation V816D of the c-kit catalytic domain enhances stem cell factor-dependent cell migration
Taylor ML; Dastych Y; Nilsson G; Metcalfe DD
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 1995;25(3):870-873
EFFECTS OF INTERLEUKIN (IL)-13 ON IMMEDIATE-EARLY RESPONSE GENE-EXPRESSION, PHENOTYPE AND DIFFERENTIATION OF HUMAN MAST-CELLS - COMPARISON WITH IL-4
NILSSON G; NILSSON K
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Grants

Reglering av mastcellers utveckling och aktivitet vid hälsa och sjukdom
Swedish Research Council
1 January 2021 - 31 December 2024
Deciphering phenotypical and functional human lung mast cell heterogeneity and its impact in chronic airway diseases
Swedish Heart-Lung Foundation
1 January 2019 - 31 December 2021

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