Granville Matheson

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Articles

Journal article: IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. 2024;71(4):1191-1196

Nonlinear Mixed-Effects Modeling Approach for Simplified Reference Tissue Model.

Shieh D; Matheson GJ; Ogden RT
Article: EJNMMI PHYSICS. 2023;10(1):72

Parametric and non-parametric Poisson regression for modelling of the arterial input function in positron emission tomography.

Matheson GJ; Ge L; Zhang M; Sun B; Tu Y; Zanderigo F; Forsberg Morèn A; Ogden RT
Article: ADDICTION. 2023;118(6):1053-1061

Striatal dopamine D2 receptor availability as a predictor of subsequent alcohol use in social drinkers.

Jangard S; Jayaram-Lindström N; Isacsson NH; Matheson GJ; Plavén-Sigray P; Franck J; Borg J; Farde L; Cervenka S
Article: EJNMMI PHYSICS. 2023;10(1):17

Multivariate analysis of PET pharmacokinetic parameters improves inferential efficiency.

Matheson GJ; Ogden RT
Article: BRAIN SCIENCES. 2022;12(10):1338

Experimental Sleep Deprivation Results in Diminished Perceptual Stability Independently of Psychosis Proneness.

Balter LJT; Matheson GJ; Sundelin T; Sterzer P; Petrovic P; Axelsson J
Journal article: NEUROIMAGE. 2022;256:119195

Simultaneous multifactor Bayesian analysis (SiMBA) of PET time activity curve data.

Matheson GJ; Ogden RT
Article: LANCET PSYCHIATRY. 2022;9(6):447-457

Improving lithium dose prediction using population pharmacokinetics and pharmacogenomics: a cohort genome-wide association study in Sweden.

Millischer V; Matheson GJ; Bergen SE; Coombes BJ; Ponzer K; Wikström F; Jagiello K; Lundberg M; Stenvinkel P; Biernacka JM; Breuer O; Martinsson L; Landén M; Backlund L; Lavebratt C; Schalling M
Article: MOLECULAR PSYCHIATRY. 2022;27(2):1233-1240

Thalamic dopamine D2-receptor availability in schizophrenia: a study on antipsychotic-naive patients with first-episode psychosis and a meta-analysis.

Plavén-Sigray P; Ikonen Victorsson P; Santillo A; Matheson GJ; Lee M; Collste K; Fatouros-Bergman H; Sellgren CM; Erhardt S; Agartz I; Halldin C; Farde L; Cervenka S
Article: HEPATOLOGY. 2021;74(6):3301-3315

Test-Retest Reliability and Consistency of HVPG and Impact on Trial Design: A Study in 289 Patients from 20 Randomized Controlled Trials.

Bai W; Al-Karaghouli M; Stach J; Sung S; Matheson GJ; Abraldes JG
Article: JOURNAL OF AFFECTIVE DISORDERS. 2021;294:645-651

A positron emission tomography study of the serotonin1B receptor effect of electroconvulsive therapy for severe major depressive episodes.

Tiger M; Gärde M; Tateno A; Matheson GJ; Sakayori T; Nogami T; Moriya H; Varnäs K; Arakawa R; Okubo Y
Article: NEUROIMAGE. 2021;226:117523

Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: A PET study of within-subject correlations with [11C]FLB 457.

Freiburghaus T; Svensson JE; Matheson GJ; Plavén-Sigray P; Lundberg J; Farde L; Cervenka S
Article: EJNMMI RESEARCH. 2020;10(1):95

Reliability of dopamine transporter PET measurements with [18F]FE-PE2I in patients with Parkinson's disease.

Kerstens VS; Fazio P; Sundgren M; Matheson GJ; Franzén E; Halldin C; Cervenka S; Svenningsson P; Varrone A
Article: SCHIZOPHRENIA RESEARCH. 2020;222:175-184

Dopamine D1 receptor availability is not associated with delusional ideation measures of psychosis proneness.

Matheson GJ; Plavén-Sigray P; Louzolo A; Borg J; Farde L; Petrovic P; Cervenka S
Article: EJNMMI RESEARCH. 2020;10(1):77

Kinfitr - an open-source tool for reproducible PET modelling: validation and evaluation of test-retest reliability.

Tjerkaski J; Cervenka S; Farde L; Matheson GJ
Journal article: SCHIZOPHRENIA BULLETIN. 2020;46(Supplement_1):s233

T7. UPDATED INDIVIDUAL PARTICIPANT DATA META-ANALYSIS CONFIRMS LOWER LEVELS OF THE GLIAL MARKER TSPO IN PSYCHOSIS PATIENTS

Plavén-Sigray P; Matheson G; Coughlin J; Hafizi S; Laurikainen H; Ottoy J; de’Picker L; Rusjan P; Hietala J; Howes O; Mizrahi R; Morrens M; Pomper M; Cervenka S
Journal article: SCHIZOPHRENIA BULLETIN. 2020;46(Supplement_1):s135-s136

M7. LOWER THALAMIC DOPAMINE D2-RECEPTOR BINDING IN DRUG-NAIVE PATIENTS WITH PSYCHOSIS – A REPLICATION STUDY USING POSITRON EMISSION TOMOGRAPHY

Victorsson P; Plavén-Sigray P; Matheson G; Santillo A; Lee M; Collste K; Fatouros-Bergman H; Agartz I; Halldin C; Farde L; Cervenka S
Article: PSYCHIATRY RESEARCH. 2020;284:112677

AKT1 and genetic vulnerability to bipolar disorder.

Millischer V; Matheson GJ; Martinsson L; Römer Ek I; Schalling M; Lavebratt C; Backlund L
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2019;22(7):415-425

D1-Dopamine Receptor Availability in First-Episode Neuroleptic Naive Psychosis Patients.

Stenkrona P; Matheson GJ; Halldin C; Cervenka S; Farde L
Article: PEERJ. 2019;7:e6918

We need to talk about reliability: making better use of test-retest studies for study design and interpretation.

Matheson GJ
Article: EJNMMI RESEARCH. 2018;8(1):102

Test-retest reliability and convergent validity of (R)-[11C]PK11195 outcome measures without arterial input function.

Plavén-Sigray P; Matheson GJ; Cselényi Z; Jucaite A; Farde L; Cervenka S
Article: BIOLOGICAL PSYCHIATRY. 2018;84(6):433-442

Positron Emission Tomography Studies of the Glial Cell Marker Translocator Protein in Patients With Psychosis: A Meta-analysis Using Individual Participant Data.

Plavén-Sigray P; Matheson GJ; Collste K; Ashok AH; Coughlin JM; Howes OD; Mizrahi R; Pomper MG; Rusjan P; Veronese M; Wang Y; Cervenka S
Article: EJNMMI RESEARCH. 2018;8(1):74

[11C]SCH23390 binding to the D1-dopamine receptor in the human brain-a comparison of manual and automated methods for image analysis.

Stenkrona P; Matheson GJ; Cervenka S; Sigray PP; Halldin C; Farde L
Article: PEERJ. 2018;6:e5790

Serotonin 5-HT1A receptor binding and self-transcendence in healthy control subjects-a replication study using Bayesian hypothesis testing.

Griffioen G; Matheson GJ; Cervenka S; Farde L; Borg J
Article: PLOS ONE. 2018;13(12):e0209584

Trait impulsivity is not related to post-commissural putamen volumes: A replication study in healthy men.

Caravaggio F; Plavén-Sigray P; Matheson GJ; Plitman E; Chakravarty MM; Borg J; Graff-Guerrero A; Cervenka S
Article: PLOS ONE. 2018;13(3):e0193770

Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study.

Plavén-Sigray P; Matheson GJ; Gustavsson P; Stenkrona P; Halldin C; Farde L; Cervenka S
Article: EJNMMI RESEARCH. 2017;7(1):58

Assessment of simplified ratio-based approaches for quantification of PET [11C]PBR28 data.

Matheson GJ; Plavén-Sigray P; Forsberg A; Varrone A; Farde L; Cervenka S
Article: ELIFE. 2017;6:e27725

The readability of scientific texts is decreasing over time.

Plavén-Sigray P; Matheson GJ; Schiffler BC; Thompson WH
Article: NEUROIMAGE. 2017;155:344-353

Reliability of volumetric and surface-based normalisation and smoothing techniques for PET analysis of the cortex: A test-retest analysis using [11C]SCH-23390.

Matheson GJ; Stenkrona P; Cselényi Z; Plavén-Sigray P; Halldin C; Farde L; Cervenka S
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27(5):462-469

Extrastriatal dopamine D2-receptor availability in social anxiety disorder.

Plavén-Sigray P; Hedman E; Victorsson P; Matheson GJ; Forsberg A; Djurfeldt DR; Rück C; Halldin C; Lindefors N; Cervenka S
Article: MOLECULAR PSYCHIATRY. 2016;21(8):1077-1084

Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain.

Borg J; Cervenka S; Kuja-Halkola R; Matheson GJ; Jönsson EG; Lichtenstein P; Henningsson S; Ichimiya T; Larsson H; Stenkrona P; Halldin C; Farde L
Article: NEUROIMAGE. 2015;112:225-231

Diurnal and seasonal variation of the brain serotonin system in healthy male subjects.

Matheson GJ; Schain M; Almeida R; Lundberg J; Cselényi Z; Borg J; Varrone A; Farde L; Cervenka S
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All other publications

Preprint: BIORXIV. 2022

Multivariate Analysis of PET Pharmacokinetic Parameters

Matheson G; Ogden T
Editorial comment: SCIENTIFIC DATA. 2022;9(1):65

PET-BIDS, an extension to the brain imaging data structure for positron emission tomography.

Norgaard M; Matheson GJ; Hansen HD; Thomas A; Searle G; Rizzo G; Veronese M; Giacomel A; Yaqub M; Tonietto M; Funck T; Gillman A; Boniface H; Routier A; Dalenberg JR; Betthauser T; Feingold F; Markiewicz CJ; Gorgolewski KJ; Blair RW; Appelhoff S; Gau R; Salo T; Niso G; Pernet C; Phillips C; Oostenveld R; Gallezot J-D; Carson RE; Knudsen GM; Innis RB; Ganz M
Preprint: BIORXIV. 2021

PET-BIDS, an extension to the brain imaging data structure for positron emission tomography

Norgaard M; Matheson G; Hansen H; Thomas A; Searle G; Rizzo G; Veronese M; Giacomel A; Yaqub M; Tonietto M; Funck T; Gillman A; Boniface H; Routier A; Dalenberg J; Betthauser T; Feingold F; Markiewicz C; Gorgolewski K; Blair R; Appelhoff S; Gau R; Salo T; Niso G; Pernet C; Phillips C; Oostenveld R; Gallezot J-D; Carson R; Knudsen G; Innis R; Ganz M
Letter: BIOLOGICAL PSYCHIATRY. 2021;89(3):e5-e8

Meta-analysis of the Glial Marker TSPO in Psychosis Revisited: Reconciling Inconclusive Findings of Patient-Control Differences.

Plavén-Sigray P; Matheson GJ; Coughlin JM; Hafizi S; Laurikainen H; Ottoy J; De Picker L; Rusjan P; Hietala J; Howes OD; Mizrahi R; Morrens M; Pomper MG; Cervenka S
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021;41(1_SUPPL):228-229

Meta-analysis of the glial marker TSPO in psychosis revisited: Reconciling inconclusive findings of patient-control differences

Plaven-Sigray P; Matheson GJ; Coughlin JM; Hafizi S; Laurikainen H; Ottoy J; de'Picker L; Rusjan PM; Hietala J; Howes OD; Mizrahi R; Morrens M; Pomper MG; Cervenka S
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021;41(1_SUPPL):260-261

Lower thalamic dopamine D2-receptor binding and connectivity in drug-naive patients with psychosis - A combined [11C]FLB 457 PET and DTI study

Victorsson P; Plaven-Sigray P; Santillo A; Matheson GJ; Lee M; Collste K; Fatouros-Bergman H; Agartz I; Halldin C; Farde L; Cervenka S
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021;41(1_SUPPL):258-260

Validation of kinfitr: An open-source tool for reproducible PET kinetic modelling

Tjerkaski J; Cervenka S; Farde L; Matheson GJ
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021;41(1_SUPPL):117-119

The positron emission tomography brain imaging data structure (PET-BIDS) extension: A new standard for sharing PET data

Norgaard M; Matheson GJ; Hansen HD; Thomas A; Searle G; Rizzo G; Veronese M; Giacomel A; Yaqub M; Tonietto M; Funck T; Gillman A; Boniface H; Routier A; Dalenberg JR; Betthauser T; Feingold F; Markiewicz CJ; Gorgolewski KJ; Blair RW; Appelhoff S; Gau R; Salo T; Niso G; Pernet C; Phillips C; Oostenveld R; Gallezot J-D; Carson RE; Knudsen GM; Innis RB; Ganz M
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2021;41(1_SUPPL):224-225

Strength in numbers: Multilevel modelling of time activity curves

Matheson GJ; Chen Y; Zanderigo F; Ogden RT
Preprint: MEDRXIV. 2020

Test-retest reliability of hepatic venous pressure gradient and impact on trial design: a study in 289 patients from the control groups of 20 randomized trials

Bai W; Al-Karaghouli M; Stach J; Matheson GJ; Abraldes JG
Review: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2020;40(8):1576-1585

Guidelines for the content and format of PET brain data in publications and archives: A consensus paper.

Knudsen GM; Ganz M; Appelhoff S; Boellaard R; Bormans G; Carson RE; Catana C; Doudet D; Gee AD; Greve DN; Gunn RN; Halldin C; Herscovitch P; Huang H; Keller SH; Lammertsma AA; Lanzenberger R; Liow J-S; Lohith TG; Lubberink M; Lyoo CH; Mann JJ; Matheson GJ; Nichols TE; Nørgaard M; Ogden T; Parsey R; Pike VW; Price J; Rizzo G; Rosa-Neto P; Schain M; Scott PJ; Searle G; Slifstein M; Suhara T; Talbot PS; Thomas A; Veronese M; Wong DF; Yaqub M; Zanderigo F; Zoghbi S; Innis RB
Preprint: RESEARCH SQUARE. 2020

Reliability of Dopamine Transporter PET Measurements with [18F]FE-PE2I in patients with Parkinson´s Disease

Kerstens V; Fazio P; Sundgren M; Matheson G; Franzén E; Halldin C; Cervenka S; Svenningsson P; Varrone A
Preprint: BIORXIV. 2020

Low convergent validity of [11C]raclopride binding in extrastriatal brain regions: a PET study of within-subject correlations with [11C]FLB 457

Freiburghaus T; Svensson JE; Matheson GJ; Plavén-Sigray P; Lundberg J; Farde L; Cervenka S
Preprint: RESEARCH SQUARE. 2020

Reliability of Dopamine Transporter PET Measurements with [18F]FE-PE2I in patients with Parkinson's Disease

Kerstens VS; Fazio P; Sundgren M; Matheson GJ; Franzén E; Halldin C; Cervenka S; Svenningsson P; Varrone A
Preprint: BIORXIV. 2020

Kinfitr – an open source tool for reproducible PET modelling: validation and evaluation of test-retest reliability

Tjerkaski J; Cervenka S; Farde L; Matheson GJ
Letter: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(2):502-504

Clinical brain PET research must embrace multi-centre collaboration and data sharing or risk its demise.

Matheson GJ; Plavén-Sigray P; Tuisku J; Rinne J; Matuskey D; Cervenka S
Conference publication: SCHIZOPHRENIA BULLETIN. 2020;46:S135-S136

LOWER THALAMIC DOPAMINE D2-RECEPTOR BINDING IN DRUG-NAIVE PATIENTS WITH PSYCHOSIS - A REPLICATION STUDY USING POSITRON EMISSION TOMOGRAPHY

Victorsson P; Plaven-Sigray P; Matheson G; Santillo A; Lee M; Collste K; Fatouros-Bergman H; Agartz I; Halldin C; Farde L; Cervenka S
Conference publication: SCHIZOPHRENIA BULLETIN. 2020;46:S233

UPDATED INDIVIDUAL PARTICIPANT DATA META-ANALYSIS CONFIRMS LOWER LEVELS OF THE GLIAL MARKER TSPO IN PSYCHOSIS PATIENTS

Plaven-Sigray P; Matheson G; Coughlin J; Hafizi S; Laurikainen H; Ottoy J; de'Picker L; Rusjan P; Hietala J; Howes O; Mizrahi R; Morrens M; Pomper M; Cervenka S
Conference publication: HEPATOLOGY. 2020;72:72A

TEST-RETEST RELIABILITY OF HEPATIC VENOUS PRESSURE GRADIENT IN 289 PATIENTS FROM THE CONTROL GROUPS OF 20 RANDOMIZED CONTROLLED TRIALS. IMPACT ON TRIAL DESIGN.

Bai W; Al-Karaghouli M; Stach J; Matheson G; Abraldes JG
Preprint: BIORXIV. 2019

kinfitr: Reproducible PET Pharmacokinetic Modelling in R

Matheson G
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(SUPPL 1):S392-S393

Reliability of Dopamine Transporter PET Measurements with [¹⁸F]FE-PE2I in Early Stage Parkinson's Disease: A Preliminary Test-Retest Evaluation

Kerstens V; Fazio P; Sundgren M; Matheson GJ; Franzen E; Halldin C; Cervenka S; Svenningsson P; Varrone A
KI thesis / dissertation: 2018

Reliability, replicability and reproducibility in PET imaging

Matheson, Granville James
Preprint: BIORXIV. 2018

Dopamine D1 receptor availability is not associated with delusional ideation measures of psychosis proneness

Matheson GJ; Plavén-Sigray P; Louzolo A; Borg J; Farde L; Petrovic P; Cervenka S
Preprint: BIORXIV. 2018

Test-retest reliability and convergent validity of (R)-[¹¹C]PK11195 outcome measures without arterial input function

Plavén-Sigray P; Matheson GJ; Cselényi Z; Jučaite A; Farde L; Cervenka S
Preprint: BIORXIV. 2018

We need to talk about reliability: Making better use of test-retest studies for study design and interpretation

Matheson G
Preprint: BIORXIV. 2017

PET studies of the glial cell marker TSPO in psychosis patients - a meta-analysis using individual participant data

Plavén-Sigray P; Matheson GJ; Collste K; Ashok AH; Coughlin JM; Howes OD; Mizrahi R; Pomper MG; Rusjan P; Veronese M; Wang Y; Cervenka S
Preprint: BIORXIV. 2017

Serotonin 5-HT_1A receptor binding and self-transcendence in healthy control subjects - a replication study using Bayesian hypothesis testing

Griffioen G; Matheson GJ; Cervenka S; Farde L; Borg J
Preprint: BIORXIV. 2017

Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study

Plavén-Sigray P; Matheson GJ; Gustavsson P; Stenkrona P; Halldin C; Farde L; Cervenka S
Preprint: BIORXIV. 2017

The readability of scientific texts is decreasing over time

Plavén-Sigray P; Matheson GJ; Schiffler BC; Thompson WH
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2017;37:165-166

Assessment of the reliability and validity of simplified ratio-based quantification approaches for [¹¹C]PBR28

Matheson GJ; Sigray PP; Forsberg A; Collste K; Varrone A; Halldin C; Farde L; Cervenka S
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2017;37:237

Serotonin 5HT_1A receptor binding and self-transcendence in healthy control subjects - a replication study using Bayesian inference

Griffioen G; Borg J; Matheson GJ; Cervenka S; Farde L
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:676

PET STUDY OF THALAMIC DOPAMINE D2-RECEPTORS IN DRUG-NAIVE PATIENTS WITH SCHIZOPHRENIA

Ikonen P; Cervenka S; Collste K; Fatouros-Bergman H; Matheson G; Sigray PP; Varrone A; Halldin C; Flyckt L; Farde L
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:674-675

ASSESSING THE DOPAMINERGIC BASIS OF DELUSIONAL IDEATION: THE RELATIONSHIP BETWEEN D1 AND D2 RECEPTOR AVAILABILITY AND DELUSIONAL BELIEFS IN HEALTHY SUBJECTS

Matheson GJ; Louzolo A; Plaven-Sigray P; Stenkrona P; Farde L; Ingvar M; Petrovic P; Cervenka S
Conference publication: INTERNATIONAL JOURNAL OF PSYCHOLOGY. 2016;51:879

Contribution of non-genetic factors to dopamine and serotonin receptor availability in the adult human brain

Borg J; Cervenka S; Kuja-Halkola R; Matheson GJ; Jonsson EG; Lichtenstein P; Henningsson S; Ichimiya T; Larsson H; Stenkrona P; Halldin C; Farde L
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:675-676

DIURNAL AND SEASONAL VARIATION OF THE BRAIN SEROTONIN SYSTEM IN HEALTHY MALE SUBJECTS

Matheson GJ; Schain M; Almeida R; Lundberg J; Cselenyi Z; Borg J; Varrone A; Farde L; Cervenka S
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:677-678

ELEVATED LEVELS OF ORBITOFRONTAL DOPAMINE D2-RECEPTORS IN PATIENTS WITH SOCIAL ANXIETY DISORDER

Sigray PP; Hedman E; Ikonen P; Matheson G; Forsberg A; Djurfeldt D; Ruck C; Halldin C; Lindefors N; Cervenka S
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Grants

A new approach for PET quantification using multilevel Bayesian modelling, and its application to study the neurobiology of depression

Swedish Research Council

1 January 2021 - 31 December 2023

Employments

Postdoctoral Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2022-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Clinical Neuroscience, Karolinska Institutet, 2019

Articles

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Grants

Employments

Degrees and Education

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