Goran Papenberg

Goran Papenberg

Principal Researcher | Docent
Visiting address: Tomtebodavägen 18 A, 17165 Solna
Postal address: H1 Neurobiologi, vårdvetenskap och samhälle, H1 ARC Psykologi Laukka, 171 77 Stockholm
Part of:

About me

  • Goran Papenberg is a Principle Researcher at the Aging Research Center. He
    conducted his PhD in Psychology at the Max Planck Institute for Human
    Development (Berlin, Germany), awarded in 2012 by the Free University in
    Berlin. Since then, he continued with this research as postdoctoral research
    fellow and assistant professor at the Aging Research Center. His main field
    of research are the molecular contributions to cognitive aging, with a
    special focus on dopamine and neuroinflammation. He uses genetic, epigenetic,
    lifestyle and neuroimaging techniques (Magnetic Resonance Imaging and
    Positron Emission Tomography) to understand the heterogeneity in brain and
    cognitive aging.

Articles

  • Article: CEREBRAL CORTEX. 2025;35(2):bhae481
    Papenberg G; Karalija N; Salami A; Johansson J; Wahlin A; Andersson M; Axelsson J; Garrett DD; Riklund K; Lindenberger U; Nyberg L; Backman L
  • Article: JOURNAL OF NEUROINFLAMMATION. 2025;22(1):24
    Crine V; Papenberg G; Johansson J; Boraxbekk C-J; Wahlin A; Lindenberger U; Lovden M; Riklund K; Backman L; Nyberg L; Karalija N
  • Article: MOLECULAR PSYCHIATRY. 2024;30(6):2335-2346
    Le Borgne J; Gomez L; Heikkinen S; Amin N; Ahmad S; Choi SH; Bis J; Grenier-Boley B; Rodriguez OG; Kleineidam L; Young J; Tripathi KP; Wang L; Varma A; Campos-Martin R; van der Lee S; Damotte V; de Rojas I; Palmal S; Lipton R; Reiman E; McKee A; De Jager P; Bush W; Small S; Levey A; Saykin A; Foroud T; Albert M; Hyman B; Petersen R; Younkin S; Sano M; Wisniewski T; Vassar R; Schneider J; Henderson V; Roberson E; DeCarli C; LaFerla F; Brewer J; Swerdlow R; Van Eldik L; Hamilton-Nelson K; Paulson H; Naj A; Lopez O; Chui H; Crane P; Grabowski T; Kukull W; Asthana S; Craft S; Strittmatter S; Cruchaga C; Leverenz J; Goate A; Kamboh MI; St George-Hyslop P; Valladares O; Kuzma A; Cantwell L; Riemenschneider M; Morris J; Slifer S; Dalmasso C; Castillo A; Kuecuekali F; Peters O; Schneider A; Dichgans M; Rujescu D; Scherbaum N; Deckert J; Riedel-Heller S; Hausner L; Molina-Porcel L; Duezel E; Grimmer T; Wiltfang J; Heilmann-Heimbach S; Moebus S; Tegos T; Scarmeas N; Dols-Icardo O; Moreno F; Perez-Tur J; Bullido MJ; Pastor P; Sanchez-Valle R; Alvarez V; Boada M; Garcia-Gonzalez P; Puerta R; Mir P; Real LM; Pinol-Ripoll G; Garcia-Alberca JM; Royo JL; Rodriguez-Rodriguez E; Soininen H; de Mendonca A; Mehrabian S; Traykov L; Hort J; Vyhnalek M; Thomassen JQ; Pijnenburg YAL; Holstege H; van Swieten J; Ramakers I; Verhey F; Scheltens P; Graff C; Papenberg G; Giedraitis V; Boland A; Deleuze J-F; Nicolas G; Dufouil C; Pasquier F; Hanon O; Debette S; Gruenblatt E; Popp J; Ghidoni R; Galimberti D; Arosio B; Mecocci P; Solfrizzi V; Parnetti L; Squassina A; Tremolizzo L; Borroni B; Nacmias B; Spallazzi M; Seripa D; Rainero I; Daniele A; Bossu P; Masullo C; Rossi G; Jessen F; Fernandez V; Kehoe PG; Frikke-Schmidt R; Tsolaki M; Sanchez-Juan P; Sleegers K; Ingelsson M; Haines J; Farrer L; Mayeux R; Wang L-S; Sims R; DeStefano A; Schellenberg GD; Seshadri S; Amouyel P; Williams J; van der Flier W; Ramirez A; Pericak-Vance M; Andreassen OA; Van Duijn C; Hiltunen M; Ruiz A; Dupuis J; Martin E; Lambert J-C; Kunkle B; Bellenguez C
  • Article: NEUROBIOLOGY OF AGING. 2024;144:56-67
    Gustavsson J; Istvanfyova Z; Papenberg G; Falahati F; Laukka EJ; Lehtisalo J; Mangialasche F; Kalpouzos G
  • Article: DIABETES CARE. 2024;47(10):1794-1802
    Dove A; Wang J; Huang H; Dunk MM; Sakakibara S; Guitart-Masip M; Papenberg G; Xu W
  • Journal article: ALZHEIMERS & DEMENTIA. 2024;20(9):5973-5995
    Mega Vascular Cognitive Impairment and Dementia (M
  • Article: CORTEX. 2024;176:53-61
    Papenberg G; Karalija N; Johansson J; Andersson M; Axelsson J; Riklund K; Lindenberger U; Nyberg L; Backman L
  • Article: EUROPEAN PSYCHIATRY. 2024;67(1):e45
    Yang W; Wang J; Dove A; Yang Y; Qi X; Guitart-Masip M; Papenberg G; Xu W
  • Article: NEUROBIOLOGY OF AGING. 2024;136:125-132
    Karalija N; Papenberg G; Johansson J; Wahlin A; Salami A; Andersson M; Axelsson J; Kuznetsov D; Riklund K; Lovden M; Lindenberger U; Backman L; Nyberg L
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S16)
    Gustavsson J; Ištvánfyová Z; Falahati F; Papenberg G; Mangialasche F; Kalpouzos G
  • Journal article: ALZHEIMERS & DEMENTIA. 2023;19(S16)
    Kalpouzos G; Magnusson F; Gustavsson J; Falahati F; Papenberg G; Mangialasche F; Vetrano DL
  • Article: NEUROIMAGE. 2023;279:120323
    Gustavsson J; Johansson J; Falahati F; Andersson M; Papenberg G; Avelar-Pereira B; Backman L; Kalpouzos G; Salami A
  • Article: CELL REPORTS. 2023;42(9):113107
    Johansson J; Nordin K; Pedersen R; Karalija N; Papenberg G; Andersson M; Korkki SM; Riklund K; Guitart-Masip M; Rieckmann A; Backman L; Nyberg L; Salami A
  • Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(36):e2302720120
    Le Guen Y; Luo G; Ambati A; Damotte V; Jansen I; Yu E; Nicolas A; de Rojasj I; Leal TP; Miyashita A; Bellenguez C; Lian MM; Parveen K; Morizono T; Park H; Grenier-Boley B; Naito T; Kucukali F; Talyansky SD; Yogeshwar SM; Sempere V; Satake W; Alvarez V; Arosio B; Belloy ME; Benussi L; Boland A; Borroni B; Bullido MJ; Caffarra P; Clarimon J; Daniele A; Darling D; Debette S; Deleuze J-F; Dichgans M; Dufouil C; During E; Duzel E; Galimberti D; Garcia-Ribas G; Maria Garcia-Alberca J; Garcia-Gonzalez P; Giedraitis V; Goldhardt O; Graff C; Grunblatt E; Hanon O; Hausner L; Heilmann-Heimbach S; Holstege H; Hort J; Jung YJ; Jurgen D; Kern S; Kuulasmaa T; Lee KH; Lin L; Masullo C; Mecocci P; Mehrabian S; de Mendonca A; Boada M; Mir P; Moebus S; Moreno F; Nacmias B; Nicolas G; Niida S; Nordestgaard BG; Papenberg G; Papma J; Parnetti L; Pasquier F; Pastor P; Peters O; Pijnenburg YAL; Pinol-Ripoll G; Popp J; Porcel LM; Jordi Perez-Tur RP; Rainero I; Ramakers I; Real LM; Riedel-Heller S; Rodriguez-Rodriguez E; Ross OA; Royo JL; Rujescu D; Scarmeas N; Scheltens P; Scherbaum N; Schneider A; Seripa D; Skoog I; Solfrizzi V; Spalletta G; Squassina A; van Swieten J; Sanchez-Valle R; Tan E-K; Tegos T; Teunissen C; Thomassen JQ; Tremolizzo L; Vyhnalek M; Verhey F; Waern M; Wiltfang J; Zhangc J; Zetterberg H; Blennow K; He Z; Williams J; Amouyel P; Jessen F; Kehoe PG; Andreassen OA; Van Duin C; Tsolaki M; Sanchez-Juan P; Frikke-Schmidt R; Sleegers K; Todau T; Zettergren A; Ingelsson M; Okada Y; Rossi G; Hiltunen M; Gim J; Ozaki K; Sims R; Foo JN; van der Fliere W; Ikeuchi T; Ramirez A; Mata I; Ruiz A; Gan-Or Z; Lambert J-C; Greicius MD; Mignot E
  • Article: JAMA NETWORK OPEN. 2023;6(5):e2313734
    Luo J; Thomassen JQ; Bellenguez C; Grenier-Boley B; de Rojas I; Castillo A; Parveen K; Kuecuekali F; Nicolas A; Peters O; Schneider A; Dichgans M; Rujescu D; Scherbaum N; Juergen D; Riedel-Heller S; Hausner L; Porcel LM; Duezel E; Grimmer T; Wiltfang J; Heilmann-Heimbach S; Moebus S; Tegos T; Scarmeas N; Clarimon J; Moreno F; Perez-Tur J; Bullido MJ; Pastor P; Sanchez-Valle R; Alvarez V; Boada M; Garcia-Gonzalez P; Puerta R; Mir P; Real LM; Pinol-Ripoll G; Garcia-Alberca JM; Royo JL; Rodriguez-Rodriguez E; Soininen H; Kuulasmaa T; de Mendonca A; Mehrabian S; Hort J; Vyhnalek M; van der Lee S; Graff C; Papenberg G; Giedraitis V; Boland A; Bacq-Daian D; Deleuze J-F; Nicolas G; Dufouil C; Pasquier F; Hanon O; Debette S; Gruenblatt E; Popp J; Benussi L; Galimberti D; Arosio B; Mecocci P; Solfrizzi V; Parnetti L; Squassina A; Tremolizzo L; Borroni B; Nacmias B; Sorbi S; Caffarra P; Seripa D; Rainero I; Daniele A; Masullo C; Spalletta G; Williams J; Amouyel P; Jessen F; Kehoe P; Magda T; Rossi G; Sanchez-Juan P; Sleegers K; Ingelsson M; Andreassen OA; Hiltunen M; Van Duijn C; Sims R; van der Flier W; Ruiz A; Ramirez A; Lambert J-C; Frikke-Schmidt R
  • Article: NEUROLOGY. 2023;100(1):e38-e48
    Li Y; Laukka EJ; Dekhtyar S; Papenberg G; Speh A; Fratiglioni L; Kalpouzos G; Qiu C
  • Article: SCIENTIFIC REPORTS. 2022;12(1):20957
    Nyberg L; Karalija N; Papenberg G; Salami A; Andersson M; Pedersen R; Vikner T; Garrett DDD; Riklund K; Wahlin A; Lovden M; Lindenberger U; Backman L
  • Article: NEUROLOGY. 2022;99(12):e1278-e1289
    Karalija N; Johansson J; Papenberg G; Wahlin A; Salami A; Kohncke Y; Brandmaier AM; Andersson M; Axelsson J; Riklund K; Lovden M; Lindenberger U; Backman L; Nyberg L
  • Article: JAMA NEUROLOGY. 2022;79(7):652-663
    Le Guen Y; Belloy ME; Grenier-Boley B; de Rojas I; Castillo-Morales A; Jansen I; Nicolas A; Bellenguez C; Dalmasso C; Küçükali F; Eger SJ; Rasmussen KL; Thomassen JQ; Deleuze J-F; He Z; Napolioni V; Amouyel P; Jessen F; Kehoe PG; van Duijn C; Tsolaki M; Sánchez-Juan P; Sleegers K; Ingelsson M; Rossi G; Hiltunen M; Sims R; van der Flier WM; Ramirez A; Andreassen OA; Frikke-Schmidt R; Williams J; Ruiz A; Lambert J-C; Greicius MD; Members of the EADB, GR@ACE, DEGESCO, DemGene, GER; Arosio B; Benussi L; Boland A; Borroni B; Caffarra P; Daian D; Daniele A; Debette S; Dufouil C; Düzel E; Galimberti D; Giedraitis V; Grimmer T; Graff C; Grünblatt E; Hanon O; Hausner L; Heilmann-Heimbach S; Holstege H; Hort J; Jürgen D; Kuulasmaa T; van der Lugt A; Masullo C; Mecocci P; Mehrabian S; de Mendonça A; Moebus S; Nacmias B; Nicolas G; Olaso R; Papenberg G; Parnetti L; Pasquier F; Peters O; Pijnenburg YAL; Popp J; Rainero I; Ramakers I; Riedel-Heller S; Scarmeas N; Scheltens P; Scherbaum N; Schneider A; Seripa D; Soininen H; Solfrizzi V; Spalletta G; Squassina A; van Swieten J; Tegos TJ; Tremolizzo L; Verhey F; Vyhnalek M; Wiltfang J; Boada M; García-González P; Puerta R; Real LM; Álvarez V; Bullido MJ; Clarimon J; García-Alberca JM; Mir P; Moreno F; Pastor P; Piñol-Ripoll G; Molina-Porcel L; Pérez-Tur J; Rodríguez-Rodríguez E; Royo JL; Sánchez-Valle R; Dichgans M; Rujescu D
  • Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2022;100(6):1296-1320
    Nordin K; Gorbach T; Pedersen R; Lundmark VP; Johansson J; Andersson M; McNulty C; Riklund K; Wahlin A; Papenberg G; Kalpouzos G; Backman L; Salami A
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All other publications

  • Book chapter: THE SAGE HANDBOOK OF COGNITIVE AND SYSTEMS NEUROSCIENCE. 2024;p. 114-132
    Korkki SM; Papenberg G; Guitart-Masip M; Salami A; Karalija N; Nyberg L; Bäckman L
  • Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):716
    de Rojas I; Moreno-Grau S; Tesi N; Grenier-Boley B; Andrade V; Jansen I; Pedersen NL; Stringa N; Zettergren A; Hernandez I; Montrreal L; Antunez C; Antonell A; Tankard RM; Bis J; Sims R; Bellenguez C; Quintela I; Gonzalez-Perez A; Calero M; Franco-Macias E; Macias J; Blesa R; Cervera-Carles L; Menendez-Gonzalez M; Frank-Garcia AC; Royo JLW; Moreno F; Huerto Vilas R; Baquero M; Diez-Fairen M; Lage C; Garcia-Madrona S; Garcia-Gonzalez P; Alarcon-Martin E; Valero S; Sotolongo-Grau O; Ullgren A; Naj AC; Lemstra AW; Benaque A; Perez-Cordon A; Benussi AL; Rabano A; Padovani A; Squassina A; de Mendonca A; Arias Pastor AM; Kok AAL; Meggy A; Pastor AB; Espinosa A; Corma-Gomez A; Martin Montes A; Sanabria A; DeStefano AW; Schneider A; Haapasalo A; Kinhult Stahlbom A; Tybjaerg-Hansen A; Hartmann AM; Spottke A; Corbaton-Anchuelo A; Rongve AB; Borroni B; Arosio B; Nacmias B; Nordestgaard BG; Kunkle BW; Charbonnier C; Abdelnour C; Masullo C; Martinez Rodriguez C; Munoz-Fernandez C; Dufouil C; Graff C; Ferreira C; Chillotti C; Reynolds CA; Fenoglio C; Van Broeckhoven C; Clark C; Pisanu C; Satizabal CL; Holmes C; Buiza-Rueda D; Aarsland D; Rujescu D; Alcolea D; Galimberti D; Wallon D; Seripa D; Grunblatt E; Dardiotis E; Duezel E; Scarpini E; Conti E; Rubino E; Gelpi E; Rodriguez-Rodriguez E; Duron E; Boerwinkle E; Ferri E; Tagliavini F; Kuecuekali F; Pasquier F; Sanchez-Garcia F; Mangialasche F; Jessen F; Nicolas G; Selbaek G; Ortega GK; Chene G; Hadjigeorgiou G; Rossi G; Spalletta G; Giaccone G; Grande G; Binetti G; Papenberg G; Hampel H; Bailly H; Zetterberg H; Soininen H; Karlsson I; Alvarez I; Appollonio I; Giegling I; Skoog I; Saltvedt I; Rainero I; Rosas Allende I; Hort J; Diehl-Schmid J; Van Dongen J; Vidal J-S; Lehtisalo J; Wiltfang J; Thomassen JQ; Kornhuber J; Haines JA; Vogelgsang J; Pineda J; Fortea J; Popp J; Deckert J; Buerger K; Morgan K; Fliessbach K; Sleegers K; Molina-Porcel L; Kilander L; Weinhold L; Farrer L; Wang L-S; Kleineidam L; Farotti LA; Parnetti L; Tremolizzo L; Hausner L; Benussi L; Froelich L; Ikram MA; Deniz-Naranjo MC; Tsolaki M; Rosende-Roca M; Lowenmark M; Hulsman M; Spallazzi M; Pericak-Vance MH; Esiri M; Bernal Sanchez-Arjona M; Dalmasso MC; Martinez-Larrad MTT; Arcaro M; Noethen M; Fernandez-Fuertes M; Dichgans M; Ingelsson M; Herrmann M; Scherer M; Vyhnalek M; Kosmidis MM; Yannakoulia MM; Schmid M; Ewers MJ; Heneka MT; Wagner M; Scamosci M; Kivipelto M; Hiltunen M; Zulaica M; Alegret M; Fornage M; Roberto N; van Schoor N; Seidu N; Banaj N; Armstrong N; Scarmeas N; Scherbaum NA; Goldhardt O; Hanon O; Peters O; Skrobot OA; Quenez O; Lerch O; Bossu P; Caffarra P; Dionigi Rossi P; Sakka P; Mecocci P; Hoffmann P; Holmans P; Fischer PA; Riederer P; Yang Q; Marshall R; Kalaria RN; Mayeux R; Vandenberghe R; Cecchetti R; Ghidoni R; Frikke-Schmidt R; Sorbi S; Haegg S; Engelborghs S; Helisalmi S; Botne Sando S; Kern S; Archetti S; Boschi S; Fostinelli S; Gil S; Mendoza S; Mead S; Ciccone S; Djurovic S; Heilmann-Heimbach S; Riedel-Heller S; Kuulasmaa T; del Ser T; Lebouvier T; Polak T; Ngandu T; Grimmer T; Bessi V; Escott-Price V; Giedraitis V; Deramecourt V; Maier W; Jian X; Pijnenburg YAL; Kehoe PG; Garcia-Ribas G; Sanchez-Juan P; Pastor P; Perez-Tur J; Pinol-Ripoll G; De Munain AL; Garcia-Alberca JM; Bullido MJ; Alvarez V; Lleo A; Real LM; Mir P; Medina M; Scheltens P; Holstege H; Marquie M; Saez ME; Carracedo A; Amouyel P; Schellenberg GD; Williams J; Seshadri S; Van Duijn C; Mather KA; Sanchez-Valle R; Serrano-Rios M; Orellana A; Tarraga L; Blennow K; Andreassen OA; Posthuma D; Clarimon J; Boada M; Van der Flier WM; Ramirez A; Lambert J-C; Van der Lee SJ; Ruiz A
  • Book chapter: THE CAMBRIDGE HANDBOOK OF COGNITIVE AGING. 2020;p. 552-567
    Papenberg G; Bäckman L
  • Corrigendum: NATURE COMMUNICATIONS. 2019;10(1):2068
    Davies G; Lam M; Harris SE; Trampush JW; Luciano M; Hill WD; Hagenaars SP; Ritchie SJ; Marioni RE; Fawns-Ritchie C; Liewald DCM; Okely JA; Ahola-Olli AV; Barnes CLK; Bertram L; Bis JC; Burdick KE; Christoforou A; DeRosse P; Djurovic S; Espeseth T; Giakoumaki S; Giddaluru S; Gustavson DE; Hayward C; Hofer E; Ikram MA; Karlsson R; Knowles E; Lahti J; Leber M; Li S; Mather KA; Melle I; Morris D; Oldmeadow C; Palviainen T; Payton A; Pazoki R; Petrovic K; Reynolds CA; Sargurupremraj M; Scholz M; Smith JA; Smith AV; Terzikhan N; Thalamuthu A; Trompet S; van der Lee SJ; Ware EB; Windham BG; Wright MJ; Yang J; Yu J; Ames D; Amin N; Amouyel P; Andreassen OA; Armstrong NJ; Assareh AA; Attia JR; Attix D; Avramopoulos D; Bennett DA; Boehmer AC; Boyle PA; Brodaty H; Campbell H; Cannon TD; Cirulli ET; Congdon E; Conley ED; Corley J; Cox SR; Dale AM; Dehghan A; Dick D; Dickinson D; Eriksson JG; Evangelou E; Faul JD; Ford I; Freimer NA; Gao H; Giegling I; Gillespie NA; Gordon SD; Gottesman RF; Griswold ME; Gudnason V; Harris TB; Hartmann AM; Hatzimanolis A; Heiss G; Holliday EG; Joshi PK; Kahonen M; Kardia SLR; Karlsson I; Kleineidam L; Knopman DS; Kochan NA; Konte B; Kwok JB; Le Hellard S; Lee T; Lehtimaki T; Li S-C; Lill CM; Liu T; Koini M; London E; Longstreth WTJ; Lopez OL; Loukola A; Luck T; Lundervold AJ; Lundquist A; Lyytikainen L-P; Martin NG; Montgomery GW; Murray AD; Need AC; Noordam R; Nyberg L; Ollier W; Papenberg G; Pattie A; Polasek O; Poldrack RA; Psaty BM; Reppermund S; Riedel-Heller SG; Rose RJ; Rotter JI; Roussos P; Rovio SP; Saba Y; Sabb FW; Sachdev PS; Satizabal CL; Schmid M; Scott RJ; Scult MA; Simino J; Slagboom PE; Smyrnis N; Soumare A; Stefanis NC; Stott DJ; Straub RE; Sundet K; Taylor AM; Taylor KD; Tzoulaki I; Tzourio C; Uitterlinden A; Vitart V; Voineskos AN; Kaprio J; Wagner M; Wagner H; Weinhold L; Wen KH; Widen E; Yang Q; Zhao W; Adams HHH; Arking DE; Bilder RM; Bitsios P; Boerwinkle E; Chiba-Falek O; Corvin A; De Jager PL; Debette S; Donohoe G; Elliott P; Fitzpatrick AL; Gill M; Glahn DC; Hagg S; Hansell NK; Hariri AR; Ikram MK; Jukema JW; Vuoksimaa E; Keller MC; Kremen WS; Launer L; Lindenberger U; Palotie A; Pedersen NL; Pendleton N; Porteous DJ; Raikkonen K; Raitakari OT; Ramirez A; Reinvang I; Rudan I; Rujescu D; Schmidt R; Schmidt H; Schofield PW; Schofield PR; Starr JM; Steen VM; Trollor JN; Turner ST; Van Duijn CM; Villringer A; Weinberger DR; Weir DR; Wilson JF; Malhotra A; McIntosh AM; Gale CR; Seshadri S; Mosley THJ; Bressler J; Lencz T; Deary IJ
  • Book chapter: COGNITIVE NEUROSCIENCE OF AGING. 2016;p. 415-438
    Papenberg G; Lindenberger U; Bäck L
  • Review: TRENDS IN COGNITIVE SCIENCES. 2015;19(9):506-514
    Papenberg G; Lindenberger U; Backman L
  • Review: NEUROPSYCHOLOGY REVIEW. 2015;25(1):47-62
    Papenberg G; Salami A; Persson J; Lindenberger U; Backman L

Grants

  • Swedish Research Council
    1 January 2024 - 31 December 2027
    Human aging is characterized by neurodegeneration and decline in long-term memory, creating major individual and societal costs. Neurogenesis describes the brain’s ability to produce new neurons into very old age, as shown in animal and human autopsy data. Adult neurogenesis occurs in the hippocampus and is necessary for successful long-term memory. Based on animal data, it is well-established that neurogenesis is crucial for memory formation and consolidation. Further, depression is associated with decreased hippocampal neurogenesis.So far, however, the importance of neurogenesis for human long-term memory and mental health has been elusive due to difficulties of quantifying biomarkers of neurogenesis in the living human brain using non-invasive measures. With new groundbreaking developments, it is now feasible to detect human neurogenic signals in vivo. Therefore, we hypothesize that the higher hippocampal neurogenic signal is related to better neurocognitive mechanisms underlying memory and lower expression of depression symptoms in middle-aged and older adults. Informed by well-established evidence from animal data, we further probe whether a 6-month intervention with Metformin, a drug used to treat type 2 diabetes, increases neurogenic signals, consequently resulting in better memory and mental health. Overall, our findings will shed light on basic mechanisms underlying human memory, which may contribute to maintenance of cognition and mental health into old age.
  • Swedish Research Council
    1 January 2023 - 31 December 2025
    Long-lasting post-COVID symptoms have severe implications for affected individuals, the healthcare system, and society as a whole. This project focuses on two common symptoms in this patient group, cognitive and olfactory deficits. We aim to increase the knowledge regarding (a) long-term effects (up to 3 years) on cognitive and olfactory function after mild COVID-19, (b) factors associated with recovering from such deficits, (c) neurological bases of cognitive and olfactory deficits, and (d) associations between remaining deficits and returning to previous levels of functioning and activities (e.g. work). The proposed project is a follow-up of an ongoing study
    following these patients over time is critical for understanding the long-term effects. The project consists of 3 parts: (1) Longitudinal follow-up of a clinical sample of post-COVID patients following mild COVID-19 with a third cognitive, olfactory, and functional assessment, (2) A second magnetic resonance imaging assessment of a subgroup of this sample and matched controls, (3) A new online questionnaire targeting functioning and well-being of a large sample of post-COVID patients, diagnosed during the first years of the pandemic. Together, the results of this project will provide important new knowledge regarding the long-term effects of COVID-19 on cognitive and olfactory performance, which factors may affect the development in these domains over time, and how they relate to functioning in everyday life.
  • Swedish Research Council
    1 January 2022 - 31 December 2024
  • Swedish Research Council
    1 January 2022 - 31 December 2024
  • Swedish Research Council
    1 December 2021 - 30 November 2025
    Long-lasting post-COVID symptoms may have severe implications for affected individuals and the healthcare system. This project focuses on two common symptoms in this patient group, cognitive and olfactory deficits. We aim to increase the knowledge regarding (a) nature, severity, and duration of long-term effects on cognitive and olfactory function after mild COVID, (b) which individuals are more likely to be affected by and recover from such deficits, (c) underlying mechanisms, and (d) associations between these deficits and returning to previous levels of functioning. Longitudinal follow-up of these patients is vital to understand the long-term effects. It is further unknown how many individuals are affected by subclinical cognitive impairments following a COVID-19 infection. The project consists of 3 parts: (1) Longitudinal follow-up of a clinical sample (Danderyd rehabilitation medicine clinic) of post-COVID patients with repeated cognitive, olfactory, and functional assessments, (2) Magnetic resonance imaging assessments of a subgroup of this sample and a matched control group, (3) Repeated cognitive testing of a population sample comparing cognitive trajectories of persons with and without previous COVID-19. These data collections will provide important new knowledge regarding the long-term effects of COVID-19 on cognitive and olfactory performance, which factors may affect the longitudinal development in these domains, and how they relate to functioning in other areas.
  • Bank of Sweden Tercentenary Foundation
    1 January 2021 - 31 December 2023
  • Swedish Research Council
    1 January 2020 - 31 December 2023
  • Swedish Research Council
    1 December 2018 - 31 December 2021
  • Swedish Research Council for Health Working Life and Welfare
    1 January 2017 - 31 December 2022

Employments

  • Principal Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2022-
  • Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2020-2022
  • Assistant Professor, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2016-2020
  • Postdoctoral Researcher, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2014-2016

Degrees and Education

  • Docent, Karolinska Institutet, 2023

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