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Research description

I am now working with a) the molecular mechanisms of Bri2 BRICHOS domain in inhibiting fibrillar aggregation—Aβ fibril formaiton and non-fibril aggregation by molecular biology, biochemistry and biophysics multidisciplinary methodology; b) high-quality recombinant Aβ42 generation from E. coli; c) large-scale production of Aβ42 and homogenous fibrils using a novel highly soluble NT* tag derived from spider flagelliform silk protein.

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