Fredrik Hjern

About me
Publications
CV
Public outreach and news

About me

My interest in research has been mainly topics related to colorectal surgery, such as diverticular disease, colorectal cancer, perioperative care (ERAS) and proctology.

Research

Diverticular disease, Colorectal cancer, Perioperative care, Rectal prolapse

Articles

Journal article: BRITISH JOURNAL OF SURGERY. 2024;111:znae175.062
Identification of diverticular disease in Swedish healthcare registers: A validation study
Mahmood WM; Schmidt PT; Olen O; Hellsing C; Hjern F; Abraham-Nordling M
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2024;59(2):176-182
Identification of diverticular disease in Swedish healthcare registers: a validation study
Mahmood MW; Schmidt PT; Olen O; Hellsing C; Hjern F; Abraham-Nordling M
Article: BJS OPEN. 2022;6(6):zrac140
The impact of hospital volume on survival in patients with locally advanced colonic cancer
Rosander E; Holm T; Sjovall A; Hjern F; Weibull CE; Nordenvall C
Article: BJS OPEN. 2022;6(1):zrab140
Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
Smedberg J; Graf W; Pekkari K; Hjern F
Article: COLORECTAL DISEASE. 2021;23(9):2387-2398
Check the placeEmergency resection or diverting stoma followed by elective resection in patients with colonic obstruction due to locally advanced cancer: a national cohort study
Rosander E; Holm T; Sjovall A; Hjern F; Weibull CE; Nordenvall C
Article: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. 2021;47(9):2398-2404
Preoperative multidisciplinary team assessment is associated with improved survival in patients with locally advanced colon cancer; a nationwide cohort study in 3157 patients
Rosander E; Holm T; Sjovall A; Hjern F; Weibull CE; Nordenvall C
Journal article: GASTROHEP. 2021;3(3):131-140
Mortality in patients hospitalised for diverticulitis in Sweden—A national population‐based cohort study
Granlund J; Sköldberg F; Hjern F; Discacciati A; Sandvei MS; Olén O; Schmidt PT
Article: EUROPEAN JOURNAL OF NUTRITION. 2019;58(6):2393-2400
High intake of dietary fibre from fruit and vegetables reduces the risk of hospitalisation for diverticular disease
Mahmood MW; Abraham-Nordling M; Hakansson N; Wolk A; Hjern F
Article: BRITISH JOURNAL OF SURGERY. 2019;106(7):930-939
Incidence and lifetime risk of hospitalization and surgery for diverticular disease
Skoldberg F; Granlund J; Discacciati A; Hjern F; Schmidt PT; Olen O
Article: ABDOMINAL RADIOLOGY. 2019;44(5):1712-1721
Morphological predictors for lymph node metastases on computed tomography in colon cancer
Rollven E; Blomqvist L; Oistamo E; Hjern F; Csanaky G; Abraham-Nordling M
Article: BRITISH JOURNAL OF SURGERY. 2019;106(6):790-798
Population-based study of surgical treatment with and without tumour resection in patients with locally recurrent rectal cancer
Westberg K; Palmer G; Hjern F; Holm T; Martling A
Article: COLORECTAL DISEASE. 2019;21(2):191-199
Robotic vs laparoscopic rectal tumour surgery: a cohort study
Asklid D; Gerjy R; Hjern F; Pekkari K; Gustafsson UO
Article: DISEASES OF THE COLON AND RECTUM. 2018;61(4):454-460
Management and Outcome After Multivisceral Resections in Patients with Locally Advanced Primary Colon Cancer
Rosander E; Nordenvall C; Sjovall A; Hjern F; Holm T
Article: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. 2018;44(1):100-107
Management and prognosis of locally recurrent rectal cancer - A national population-based study
Westberg K; Palmer G; Hjern F; Johansson H; Holm T; Martling A
Article: BRITISH JOURNAL OF SURGERY. 2017;104(13):1866-1873
Population-based study of factors predicting treatment intention in patients with locally recurrent rectal cancer
Westberg K; Palmer G; Hjern F; Nordenvall C; Johansson H; Holm T; Martling A
Article: ACTA RADIOLOGICA. 2017;58(11):1288-1293
The value of preoperative computed tomography combined with ultrasound in the investigation of small indeterminate liver lesions in patients with colorectal cancer
Abraham-Nordling M; Oistamo E; Josephson T; Hjern F; Blomqvist L
Article: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. 2017;43(8):1433-1439
The impact of perioperative fluid therapy on short-term outcomes and 5-year survival among patients undergoing colorectal cancer surgery - A prospective cohort study within an ERAS protocol
Asklid D; Segelman J; Gedda C; Hjern F; Pekkari K; Gustafsson UO
Article: THE LANCET ONCOLOGY. 2017;18(3):336-346
Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial
Erlandsson J; Holm T; Pettersson D; Berglund A; Cedermark B; Radu C; Johansson H; Machado M; Hjern F; Hallbook O; Syk I; Glimelius B; Martling A
Article: WORLD JOURNAL OF SURGICAL ONCOLOGY. 2016;14(1):232
Emergency management with resection versus proximal stoma or stent treatment and planned resection in malignant left-sided colon obstruction
Oistamo E; Hjern F; Blomqvist L; Falken Y; Pekkari K; Abraham-Nordling M
Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2016;95(5):528-533
Transanal submucosal polyacrylamide gel injection treatment of anal incontinence: a randomized controlled trial
Altman D; Hjern F; Zetterstrom J
Article: COLORECTAL DISEASE. 2016;18(2):187-194
Laparoscopic and open right-sided colonic resection in daily routine practice. A prospective multicentre study within an Enhanced Recovery After Surgery (ERAS) protocol
Tiefenthal M; Asklid D; Hjern F; Matthiessen P; Gustafsson UO
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2016;51(2):203-210
A population-based case-control study on statin exposure and risk of acute diverticular disease
Skoldberg F; Svensson T; Olen O; Hjern F; Schmidt PT; Ljung R
Article: ANNALS OF SURGERY. 2015;261(6):1153-1159
The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection Results From an International Registry
Currie A; Burch J; Jenkins JT; Faiz O; Kennedy RH; Ljungqvist O; Demartines N; Hjern F; Norderval S; Lassen K; Revhaug A; Koczkas T; Nygren J; Gustafsson U; Kornfeld D; Slim K; Hill A; Soop M; Carlander J; Lundberg O; Fearon K; Kennedy R; Jenkins JT
Article: BRITISH JOURNAL OF SURGERY. 2015;102(1):119-124
Cohort study of corticosteroid use and risk of hospital admission for diverticular disease
Hjern F; Mahmood MW; Abraham-Nordling M; Wolk A; Hakansson N
Article: WORLD JOURNAL OF SURGICAL ONCOLOGY. 2013;11:133
Clinicopathological analysis of colorectal cancer: a comparison between emergency and elective surgical cases
Ghazi S; Berg E; Lindblom A; Lindforss U
Article: ACTA RADIOLOGICA. 2013;54(3):237-241
Cancer and diverticulitis of the sigmoid colon. Differentiation with computed tomography versus magnetic resonance imaging: preliminary experiences
Oistamo E; Hjern F; Blomqvist L; Von Heijne A; Abraham-Nordling M
Article: JOURNAL OF GASTROENTEROLOGY. 2012;47(6):619-634
Analysis of colorectal cancer morphology in relation to sex, age, location, and family history.
Ghazi S; Lindforss U; Lindberg G; Berg E; Lindblom A; Papadogiannakis N; Low-Risk Colorectal Cancer Study Group
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2012;35(9):1103-1107
The genetic influence on diverticular disease - a twin study
Granlund J; Svensson T; Olen O; Hjern F; Pedersen NL; Magnusson PKE; Schmidt PT
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2012;107(2):296-302
Obesity, Physical Inactivity, and Colonic Diverticular Disease Requiring Hospitalization in Women: A Prospective Cohort Study
Hjern F; Wolk A; Hakansson N
Article: BRITISH JOURNAL OF SURGERY. 2012;99(2):186-191
Randomized clinical trial of fluid restriction in colorectal surgery
Abraham-Nordling M; Hjern F; Pollack J; Prytz M; Borg T; Kressner U
Article: NATURE GENETICS. 2011;43(11):1098-1103
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
Stacey SN; Sulem P; Jonasdottir A; Masson G; Gudmundsson J; Gudbjartsson DF; Magnusson OT; Gudjonsson SA; Sigurgeirsson B; Thorisdottir K; Ragnarsson R; Benediktsdottir KR; Nexo BA; Tjonneland A; Overvad K; Rudnai P; Gurzau E; Koppova K; Hemminki K; Corredera C; Fuentelsaz V; Grasa P; Navarrete S; Fuertes F; Garcia-Prats MD; Sanambrosio E; Panadero A; De Juan A; Garcia A; Rivera F; Planelles D; Soriano V; Requena C; Aben KK; van Rossum MM; Cremers RGHM; van Oort IM; van Spronsen D-J; Schalken JA; Peters WHM; Helfand BT; Donovan JL; Hamdy FC; Badescu D; Codreanu O; Jinga M; Csiki IE; Constantinescu V; Badea P; Mates IN; Dinu DE; Constantin A; Mates D; Kristjansdottir S; Agnarsson BA; Jonsson E; Barkardottir RB; Einarsson GV; Sigurdsson F; Moller PH; Stefansson T; Valdimarsson T; Johannsson OT; Sigurdsson H; Jonsson T; Jonasson JG; Tryggvadottir L; Rice T; Hansen HM; Xiao Y; Lachance DH; Neill BPO; Kosel ML; Decker PA; Thorleifsson G; Johannsdottir H; Helgadottir HT; Sigurdsson A; Steinthorsdottir V; Lindblom A; Sandler RS; Keku TO; Banasik K; Jorgensen T; Witte DR; Hansen T; Pedersen O; Jinga V; Neal DE; Catalona WJ; Wrensch M; Wiencke J; Jenkins RB; Nagore E; Vogel U; Kiemeney LA; Kumar R; Mayordomo JI; Olafsson JH; Kong A; Thorsteinsdottir U; Rafnar T; Stefansson K
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2011;34(6):675-681
Diverticular disease and the risk of colon cancer - a population-based case-control study
Granlund J; Svensson T; Granath F; Hjern F; Ekbom A; Blomqvist P; Schmidt PT
Article: BRITISH JOURNAL OF SURGERY. 2011;98(7):997-1002
Smoking and the risk of diverticular disease in women
Hjern F; Wolk A; Hakansson N
Article: BRITISH JOURNAL OF CANCER. 2010;103(4):575-580
Association studies on 11 published colorectal cancer risk loci
von Holst S; Picelli S; Edler D; Lenander C; Dalen J; Hjern F; Lundqvist N; Lindforss U; Pahlman L; Smedh K; Tornqvist A; Holm J; Janson M; Andersson M; Ekelund S; Olsson L; Ghazi S; Papadogiannakis N; Tenesa A; Farrington SM; Campbell H; Dunlop MG; Lindblom A
Article: EUROPEAN JOURNAL OF CANCER. 2010;46(6):1041-1048
Common variants in human CRC genes as low-risk alleles
Picelli S; Zajac P; Zhou X-L; Edler D; Lenander C; Dalen J; Hjern F; Lundqvist N; Lindforss U; Pahlman L; Smedh K; Tornqvist A; Holm J; Janson M; Andersson M; Ekelund S; Olsson L; Lundeberg J; Lindblom A
Article: BRITISH JOURNAL OF SURGERY. 2010;97(2):251-257
Influence of hysterectomy on fistula formation in women with diverticulitis
Altman D; Forsgren C; Hjern F; Lundholm C; Cnattingius S; Johansson ALV
Article: CLINICAL RADIOLOGY. 2007;62(7):645-650
CT colonography versus colonoscopy in the follow-up of patients after diverticulitis -: A prospective, comparative study
Hjern F; Jonas E; Holmstrom B; Josephson T; Mellgren A; Johansson C
Article: CLINICAL CANCER RESEARCH. 2007;13(12):3748-3752
Lack of an association between the TGFBR1*6A variant and colorectal cancer risk
Skoglund J; Song B; Dalen J; Dedorson S; Edler D; Hjern F; Holmo J; Lenander C; Lindforss U; Lundqvist N; Olivecrona H; Olsson L; Pahlman L; Rutegard J; Smedh K; Toernqvist A; Houlston RS; Lindblom A
Article: COLORECTAL DISEASE. 2007;9(5):438-442
Management of diverticular fistulae to the female genital tract
Hjern F; Goldberg SM; Johansson C; Parker SC; Mellgren A
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2007;42(1):41-47
Conservative treatment of acute colonic diverticulitis:: Are antibiotics always mandatory?
Hjern F; Josephson T; Altman D; Holmstrom B; Mellgren A; Pollack J; Johansson C
Article: ANTICANCER RESEARCH. 2006;26(6C):4885-4888
The CHEK2 1100delC variant in Swedish colorectal cancer
Djureinovic T; Lindblom A; Dalen J; Dedorson S; Edler D; Hjern F; Holm J; Lenander C; Lindforss U; Lundqvist N; Olivecrona H; Olsson L; Pahlman L; Rutegard J; Smedh K; Tornqvist A; Eiberg H; Bisgaard ML
Article: ALIMENTARY PHARMACOLOGY AND THERAPEUTICS. 2006;23(6):797-805
Diverticular disease and migration - the influence of acculturation to a Western lifestyle on diverticular disease
Hjern F; Johansson C; Mellgren A; Baxter NN; Hjern A
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All other publications

Letter: BJS OPEN. 2022;6(2):zrac043
Author response to: Comparison of four surgical approaches for rectal prolapse: multicentre randomized clinical trial
Smedberg J; Graf W; Pekkari K; Hjern F
Published conference paper: BRITISH JOURNAL OF SURGERY. 2012;99(4):532-539
Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis
Chabok A; Pahlman L; Hjern F; Haapaniemi S; Smedh K
Published conference paper: BRITISH JOURNAL OF SURGERY. 2008;95(6):758-764
Outcome of younger patients with acute diverticulitis
Hjern F; Josephson T; Altman D; Holmstrom B; Johansson C
Thesis / dissertation: 2006
Aspects on diverticular disease
Hjern, Fredrik
Published conference paper: DISEASES OF THE COLON AND RECTUM. 2006;49(1):28-35
Pelvic organ prolapse and urinary incontinence in women with surgically managed rectal prolapse: A population-based case-control study
Altman D; Zetterstrom J; Schultz I; Nordenstam J; Hjern F; Lopez A; Mellgren A
Published conference paper: DISEASES OF THE COLON AND RECTUM. 2005;48(6):1233-1241
Functional and anatomic outcome after transvaginal rectocele repair using collagen mesh:: A prospective study
Altman D; Zetterström J; López A; Anzén B; Falconer C; Hjern F; Mellgren A

Employments

Affiliated to Research, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2012
Doctor Of Philosophy, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2006
University Medical Degree, Karolinska Institutet, 1994

Supervisor

Jannica Smedberg, Rectal prolapse - aspects of incidence, etiology and results after surgical treatment, 2022
Emma Rosander, Aspects of locally advanced colon cancer, 2015
Karin Westberg, Locally recurrent rectal cancer-aspects on management, surgery and outcome

About me

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