Frederick Zeiler

Frederick Zeiler

Affiliated to Research
Visiting address: Hotel Carolina Tower, Plan 4, Eugeinavägen 6, 17164 Solna
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Thelin, 171 77 Stockholm
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About me

  • Dr. Zeiler is an affiliated research in the Dept of Clinical Neurosciences
    who specializes in biosignal analytics, time series modelling and biomedical
    engineering approaches in traumatic brain injury
    Frederick Zeiler is a Canadian neurosurgeon who is currently an Associate
    Professor in the Depts of Surgery, Human Anatomy and Cell Science, and
    Biomedical Engineering at the University of Manitoba (UM), and the endowed
    Professor of Neuroscience at the Rady Faculty of Health Science at the UM. He
    is also an affiliated researcher with the Dept of Clinical Neuroscience at
    the KI. He completed his bachelor of science degree at UM, focused on applied
    mathematics and physical chemistry. He went on to complete his medical school
    at UM, followed by his neurosurgery residency at the same institution,
    receiving certification in neurosurgery from the Royal College of Surgeons of
    Canada. Dr. Zeiler has also completed dedicated fellowship training in both
    neurocritical care at the Montreal Neurological Institute, and the Royal
    College of Physicians and Surgeons of Canada (RCPSC) clinician investigator
    program at UM. Finally, he completed his PhD training at the University of
    Cambridge, with his studies focused on advanced multi-modal monitoring of
    cerebrovascular reactivity in adult moderate and severe traumatic brain
    injury (TBI), under the supervision of world experts in TBI research:
    professors David Menon and Marek Czosnyka. During his time in Cambridge, he
    was recognized as both a Royal College of Surgeons of Canada Travelling
    Fellow in Surgery and University of Cambridge International Trust Scholar for
    the entirety of his studies. Dr. Zeiler is the author of over 320
    peer-reviewed manuscripts, abstracts and textbook chapter publications, and
    recipient of numerous awards for academic accomplishments.
    * Manitoba Public Insurance (MPI) Professorship in Neuroscience (Endowed
    University Professorship) (2022-Present)
    * Falconer Rh Award, Winnipeg Rh Institute Foundation, University of
    Manitoba (2020)
    * Centre on Aging Fellowship, University of Manitoba (2020)
    * Rudy Falk Clinician-Scientist Professorship, University of Manitoba (2019
    – 2022)
    * Cambridge International Trust Scholar, University of Cambridge (2016-2019)
    * Harry S. Morton Travelling Fellow in Surgery, Royal College of Physicians
    and Surgeons of Canada (2016-17; 2017-18)
    * R. Samuel McLaughlin Fellowship, Manitoba Medical Service
    Foundation/University of Manitoba (2016)
    * PhD (cerebrovascular physiology in TBI), University of Cambridge
    * Certification (clinician-investigator), Royal College of Physicians and
    Surgeons of Canada
    * Fellowship (clinician-investigator), University of Manitoba
    * Certification/Fellowship (neurosurgery), Royal College of Physicians and
    Surgeons of Canada
    * Fellowship (neurocritical care), Montreal Neurological Institute, McGill
    * Residency (neurosurgery), University of Manitoba
    * Medical Doctorate, University of Manitoba
    * Primary Care Paramedic, CritCare Paramedic Academy
    * Bachelor of Science, University of Manitoba

Research

  • Dr. Zeiler leads the Winnipeg Acute TBI Laboratories at Health Sciences
    Centre in Winnipeg. His research program is focused on the application of
    multi-modal invasive/non-invasive cranial physiologic monitoring for the
    continuous assessment of cerebral autoregulation, compensatory reserve,
    autonomics and signal entropy. This program integrates complex high-frequency
    signal processing, with neuroimaging, serum/CSF/microdialysis protein and
    genetic biomarkers. The goal is to uncover the molecular mechanisms involved
    in impaired cerebrovascular reactivity in TBI, leading to the development of
    potential therapeutic targets directed at prevention and treatment of
    vascular dysfunction in TBI. His lab is funded through a variety of local,
    national and international sources, including: the Manitoba Public Insurance
    (MPI) Neuroscience Research Endowment/Operating Fund, Canadian Institutes of
    Health Research (CIHR), Canada Foundation for Innovation (CFI), the National
    Institutes of Health (NIH) and the Natural Sciences and Engineering Research
    Council of Canada (NSERC).

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