Florian Rosenberger

I am an independent group leader harnessing mass spectrometry-based proteomics to trace the molecular origins and consequences of mitochondrial dysfunction.

What happens when mitochondria don't function properly? At the Proteomes of Metabolism lab, we investigate how mitochondria support cellular integrity, adapt to metabolic challenges, and contribute to disease when their function is impaired. Our research focuses particularly on genetically defined mitochondrial disorders. We apply the latest generation of spatial and single-cell proteomics by mass spectrometry, including Deep Visual Proteomics (DVP). This technology enables us to analyze individual cells within their native tissue context, including human biopsies.