Florian Rosenberger

About me
Publications
CV
Public outreach and news

Research

I am interested in protein modifications, specifically methylation and
phosphorylation, and their impact on mitochondrial function. My expertise
lies in combining genetic models, wet lab experiments and bioinformatic tools
to pinpoint events that cause human disease.

Articles

Article: HUMAN MUTATION. 2021;42(4):378-384
Severe congenital lactic acidosis and hypertrophic cardiomyopathy caused by an intronic variant in NDUFB7
Correia SP; Moedas MF; Naess K; Bruhn H; Maffezzini C; Calvo-Garrido J; Lesko N; Wibom R; Schober FA; Jemt A; Stranneheim H; Freyer C; Wedell A; Wredenberg A
Article: NEUROLOGY-GENETICS. 2021;7(2):e566
Novel Mutation m.10372A>G in MT-ND3 Causing Sensorimotor Axonal Polyneuropathy
Bruhn H; Samuelsson K; Schober FA; Engvall M; Lesko N; Wibom R; Nennesmo I; Calvo-Garrido J; Press R; Stranneheim H; Freyer C; Wedell A; Wredenberg A
Article: SCIENCE ADVANCES. 2021;7(8):eabf0717
The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters
Schober FA; Moore D; Atanassov I; Moedas MF; Clemente P; Vegvari A; El Fissi N; Filograna R; Bucher A-L; Hinze Y; The M; Hedman E; Chernogubova E; Begzati A; Wibom R; Jain M; Nilsson R; Kall L; Wedell A; Freyer C; Wredenberg A
Article: NUCLEIC ACIDS RESEARCH. 2021;49(1):354-370
Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly
Cipullo M; Pearce SF; Sanchez IGL; Gopalakrishna S; Kruger A; Schober F; Busch JD; Li X; Wredenberg A; Atanassov I; Rorbach J
Article: METHODS IN MOLECULAR BIOLOGY. 2021;2192:75-87
Quantitative Proteomics in Drosophila with Holidic Stable-Isotope Labeling of Amino Acids in Fruit Flies (SILAF).
Schober FA; Atanassov I; Freyer C; Wredenberg A
Article: FRONTIERS IN NEUROLOGY. 2021;12:652590
Case Report: A Novel Mutation in the Mitochondrial MT-ND5 Gene Is Associated With Leber Hereditary Optic Neuropathy (LHON)
Engvall M; Kawasaki A; Carelli V; Wibom R; Bruhn H; Lesko N; Schober FA; Wredenberg A; Wedell A; Traisk F
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100065
Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits
Rosenberger FA; Atanassov I; Moore D; Calvo-Garrido J; Moedas MF; Wedell A; Freyer C; Wredenberg A
Article: EMBO MOLECULAR MEDICINE. 2020;12(7):e11659
FBXL4 deficiency increases mitochondrial removal by autophagy
Alsina D; Lytovchenko O; Schab A; Atanassov I; Schober FA; Jiang M; Koolmeister C; Wedell A; Taylor RW; Wredenberg A; Larsson N-G
Article: NUCLEIC ACIDS RESEARCH. 2019;47(17):9386-9399
C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis
Gopalakrishna S; Pearce SF; Dinan AM; Schober FA; Cipullo M; Spahr H; Khawaja A; Maffezzini C; Freyer C; Wredenberg A; Atanassov I; Firth AE; Rorbach J
Article: PLOS GENETICS. 2019;15(7):e1008240
Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo
Pajak A; Laine I; Clemente P; El-Fissi N; Schober FA; Maffezzini C; Calvo-Garrido J; Wibom R; Filograna R; Dhir A; Wedell A; Freyer C; Wredenberg A
Article: EMBO REPORTS. 2019;20(6):e48101
TEFM regulates both transcription elongation and RNA processing in mitochondria
Jiang S; Koolmeister C; Misic J; Siira S; Kuehl I; Ramos ES; Miranda M; Jiang M; Posse V; Lytovchenko O; Atanassov I; Schober FA; Wibom R; Hultenby K; Milenkovic D; Gustafsson CM; Filipovska A; Larsson N-G
Article: STEM CELL REPORTS. 2019;12(4):696-711
SQSTM1/p62-Directed Metabolic Reprogramming Is Essential for Normal Neurodifferentiation
Calvo-Garrido J; Maffezzini C; Schober FA; Clemente P; Uhlin E; Kele M; Stranneheim H; Lesko N; Bruhn H; Svenningsson P; Falk A; Wedell A; Freyer C; Wredenberg A
Article: HUMAN MOLECULAR GENETICS. 2017;26(13):2515-2525
A multi-systemic mitochondrial disorder due to a dominant p.Y955H disease variant in DNA polymerase gamma
Siibak T; Clemente P; Bratic A; Bruhn H; Kauppila TES; Macao B; Schober FA; Lesko N; Wibom R; Naess K; Nennesmo I; Wedell A; Peter B; Freyer C; Falkenberg M; Wredenberg A

All other publications

Thesis / dissertation: 2021
Systems biology of mitochondrial dysfunction
Schober, Florian A

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2021
Degree Of Master Of Medical Science 120 Credits, Karolinska Institutet, 2015

Research

Articles

All other publications

Degrees and Education

News from KI

Events from KI