Federico Iovino

Federico Iovino

Principal Researcher | Docent
Telephone: +46852487121
Visiting address: Solnavägen 9, Biomedicum, kvarter D7, 17165 Solna
Postal address: C4 Neurovetenskap, C4 Forskning Iovino, 171 77 Stockholm

About me

  • Associate Professor (Docent), Principal Investigator and Group Leader I have studied Human Biology and Biomedical Sciences, bachelor and master, at the University of Pavia in Italy. After my undergraduate studies, I moved to the University Medical Center of Groningen, The Netherlands, to do my PhD in Medical Microbiology under the supervision of Prof. Jan Maarten van Dijl and Prof. Grietje Molema studying how Streptococcus pneumoniae interact with endothelial cells causing meningitis. In 2010, I have been visiting PhD student in the lab of Prof. Carlos Orihuela in the Department of Microbiology and Immunology at the University of Texas Health Science Center in San Antonio, USA. After my PhD graduation in November 2013, I have immediately started my postdoc in December 2013 at the Karolinska Institutet, Department of Microbiology, Tumor and Cell Biology (MTC) where I continued my studies on pneumococcal meningitis. My postdoc studies have been published in the leading journals Journal of Clinical Investigation, Journal of Experimental Medicine, Trends in Microbiology, and Journal of Infectious Diseases. I was awarded in 2018 with the Four-year funding for Assistant Professor position by the Karolinska Institutet Board of Research and in 2020 with the Starting Grant in Medicine and Health from the Swedish Research Council (Vetenskapsrådet). Because of my profound interest in nervous system infections, in January 2021 I have started my own independent laboratory of Neuro-Infections and Neuroinflammation at the Department of Neuroscience at Karolinska Institutet. I was appointed Docent (Associate Professor) in Medical Microbiology in December 2021 and Principal Researcher in April 2023. The Iovino Laboratory website: Neuro-infections and neuro-inflammation – Federico Iovino Group | Karolinska Institutet (ki.se) BIBLIOMETRICS Total number of publications on Pubmed: 30 Pubmed link: https://pubmed.ncbi.nlm.nih.gov/?term=iovino+federico&sort=date [2] Total number of last-author and corresponding-author publications: 10 Total number of first-author publications: 16 Citations and h-index: https://scholar.google.com/citations?user=M-sgn1kAAAAJ&hl=sv Total Impact Points: 210 RESEARCH GRANTS 2024: Magnus Bergvall Foundation, INCATE (supporting innovators to fight drug-resistant infections). 2023: Wera Ekström Fund for Pediatric Research, Magnus Bergvall Foundation, Strategic Fund (Dept Neuroscience, KI), Stiftelsen Tysta Skolan, ItsME Foundation, HKH Crown Princess Lovisa's Association for Child Care, Therakind Limited (Pharmaceutical company, London, UK), Åhlén Foundation, Gun & Bertil Stohne Foundation. 2022: European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Bjarne Ahlström Memorial Fund in Clinical Neurology, Åhlén Foundation, Magnus Bergvall Foundation 2021: Magnus Bergvall Foundation Stiftelsen för Gamla Tjänarinnor, MSD Sverige Meningitis Study Group, Tore Nilson Foundation. 2020: Vetenskapsrådet Four-year Starting Grant Medicine & Health, Bjarne Ahlström Memorial Fund Prize in Clinical Neurology, Karolinska Institutet Research Foundation Grants, Clas Groschinsky Memorial Fund, HKH Crown Princess Lovisa's Association for Child Care, Magnus Bergvall Foundation, Tore Nilson Foundation. 2019: StratNeuro Start-up grant, Petrus and Augusta Hedlund Foundation, Åke Wiberg Foundation, Clas Groschinsky Memorial Fund, Loo and Hans Osterman Foundation (Geriatrics), Fredrik and Ingrid Thuring Foundation. 2018: Four-year Faculty-funded Assistant Professor Position (Karolinska Instituet Committee for Research), Petrus and Augusta Hedlund Foundation, Jeansson Foundation, Åke Wiberg Foundation, HKH Crown Princess Lovisa's Association for Child Care, Stiftelsen Längmanska Culture Foundation (Kulturfonden), Karolinska Institutet Research Foundation (Pediatrics), Karolinska Institutet Research Foundation Grants, Fredrik and Ingrid Thuring Foundation. 2017: Jeansson Foundation, Åke Wiberg Foundation. AWARDS AND PRIZES World Expert Recognition: In November 2021, recognized as “World Expert” in the top 0.1% of scholars in the category “Streptococcus pneumoniae” and "Pneumococcal meningitis" shortly afterwards. https://news.ki.se/federico-iovino-recognisedworld-expert-by-expertscape [4] Prize for Research in Clinical Neurology: in September 2020, from Bjarne Ahlström Memorial Fund Prize https://news.ki.se/federico-iovino-awarded-the-bjarne-ahlstrom-minnesfonds-pris-2020-for-research-in-clinical [5] REVIEWER ACTIVITY Scientific Journals: Nature Communications, Cell Systems, eBioMedicine (The Lancet), Scientific Reports (Nature publishing group), BMC Journal of Biomedical Science, PLOS One, Journal of Neuroinflammation, Molecular Neurobiology, Brain Research, Cellular and Molecular Neurobiology, Neurotoxicology and Teratology, Neuroscience Letters, Journal of Innate Immunity, Journal of Immunology, mBio (American Society of Microbiology), PLOS Pathogens, Molecular Microbiology, Journal of Bacteriology, The International Journal of Medical Microbiology, Microbiology (Microbiology Society), Microbial Pathogenesis, Pathogens and Disease (FEMS), Virulence, Frontiers in Cellular and Infection Microbiology, Frontiers in Immunology, Frontiers in Pediatrics, Frontiers in Bioengineering and Biotechnology, Current Research in Microbial Sciences, Infection and Drug Resistance, Heliyon (Cell Press), Experimental and Molecular Pathology, Annals of Medicine, BMJ (British Medical Journal) Case Reports. Grants: European Society of Clinical Microbiology and Infectious Diseases (ESCMID), UK Medical Research Council, French National Research Agency, Swiss National Science Foundation, Caixa Foundation (Caixa Research Health Call, Spain), Estonian Research Council, CIISA grant call (Centre for Interdisciplinary Research in Animal Health, University of Lisbon, Portugal), Karolinska Institutet Research Foundation Grants. EDITORIAL ACTIVITY Editorial Board Member: Frontiers in Cellular and Infection Microbiology (IF 5.7), specialty section "Bacteria and Host". Book editor: "Streptococcus pneumoniae", new volume for lab protocol based book series "Methods in Molecular Biology", published by Springer. https://link.springer.com/book/10.1007%2F978-1-4939-9199-0 [6] Section "Clinical Infectious Diseases", part of the "Encyclopedia of Infection and Immunity", published by Elsevier. https://www.elsevier.com/books/encyclopedia-of-infection-and-immunity/rezaei/978-0-12-818731-9 [7] SPECIAL ASSIGNMENTS PI representative, Advisory Board of Department of Neuroscience, KI. Safety representative, Department of Neuroscience and Work Environment Group Biomedicum, KI. Seminar organizer, Department of Neuroscience Scientific Seminars ACADEMIC EDUCATION 2013: PhD in Medical Microbiology (University of Groningen, The Netherlands). 2008: Master in Experimental and Applied Biology, Class of Human Biology and Biomedical Sciences (University of Pavia, Italy). 2006: Bachelor in Biological Sciences, Class of Human Biology and Biomedical Sciences (University of Pavia, Italy). [1] https://ki.se/en/neuro/iovino-laboratory [2] https://pubmed.ncbi.nlm.nih.gov/?term=iovino+federico&sort=date [3] https://scholar.google.com/citations?user=M-sgn1kAAAAJ&hl=en&authuser=1 [4] https://news.ki.se/federico-iovino-recognisedworld-expert-by-expertscape [5] https://news.ki.se/federico-iovino-awarded-the-bjarne-ahlstrom-minnesfonds-pris-2020-for-research-in-clinical [6] https://link.springer.com/book/10.1007%2F978-1-4939-9199-0 [7] https://www.elsevier.com/books/encyclopedia-of-infection-and-immunity/rezaei/978-0-12-818731-9

Research

  • In my laboratory, we investigate bacterial interactions with brain cells during bacterial meningoencephalitis pathogenesis. For a detailed overview of all the research projects conducted in my laboratory, please visit Neuro-infections and neuro-inflammation – Federico Iovino Group | Karolinska Institutet (ki.se)

Teaching

  • Course coordinator and Lecturer: “Interplay between neuro-infections and neurodegenerative diseases”, PhD Course, Neuroscience Doctoral Program (2023-ongoing)
  • “Bacteriology” Course, Biomedicine Bachelor Program (2016-2022). Lecturer: Infection and Immunology, and Medical Microbiology, “Illness and Disease” Course, Study Program of Medicine
  • “Pneumococcal Infections”, “Cellular and Molecular Infection” PhD course. Laboratory teacher: “Medical Microbiology” Course, Study Program of Medicine
  • “Bacteriology” Laboratory Course, Biomedicine Bachelor Program. Examining teacher: “Frontiers in Biomedicine” Course, Biomedicine Master Program.

Articles

All other publications

Grants

  • Supporting innovators to fight drug-resistant infections
    INCATE
    1 May 2024
  • Blocking bacterial interaction with neurons: a new therapeutic strategy to prevent permanent neurological damage caused by brain infections
    Magnus Bergvall Foundation
    1 February 2024
  • The bacteria-neuron blockade, the FIRST therapeutic approach to prevent permanent neurological damage caused by infections
    Gun & Bertil Stohne Foundation
    1 January 2024
  • Preventing neurological disabilities caused by perinatal brain infections
    Åhlén Foundation
    1 January 2024
  • Novel fusion proteins with bacteriocidic, anti-neurotoxic and antibiotic synergistic properties to improve pneumococcal meningitis treatment
    HKH Crown Princess Lovisa's Association for Childcare
    1 November 2023 - 1 November 2024
  • Preventing permanent severe hearing loss caused by brain infections
    Tysta Skolan Foundation
    1 May 2023
  • Bakteriell interaktion med neuroner: ett nytt terapeutiskt mål mot hjärninfektioner
    Magnus Bergvall Foundation
    1 February 2023
  • A new therapeutic approach to prevent permanent neurological disabilities in infants and children affected by brain infections
    Wera Ekström Fund for Pediatric Research
    1 February 2023
  • Blockade of pneumococcal‐neuron interaction to prevent neuronal damage in bacterial meningitis
    European Society of Clinical Microbiology and Infectious Diseases
    1 January 2023 - 1 January 2024
  • Establishment of the first therapeutic approach to prevent permanent neurological disabilities caused by brain bacterial infections
    Bjarne Alhström Memorial Fund
    1 January 2023
  • Prevention of neurological disabilities caused by perinatal brain infections
    Åhlén Foundation
    1 January 2023
  • Bacterial interaction with neurons: a new therapeutic target against brain infections
    Magnus Bergvall Foundation
    1 January 2022
  • Preventing irreparable neurological damage after bacterial meningitis by blocking pathogen interaction with neurons
    Tore Nilson Foundation
    1 January 2022
  • Preventing neuronal loss that leads to Parkinson's and Alzheimer's diseases
    Foundation of the Elderly
    1 May 2021
  • Förhindra irreparabel neurologisk skada efter bakteriell meningit genom att blockera patogeninteraktion med neuroner
    Magnus Bergvall Foundation
    1 January 2021
  • Bacterial Meningitis: Understanding Bacterial Interactions with Microglia and Neurons to Develop New Methods to Boost the Brain Immune System and Prevent Neuronal Damage
    Tore Nilson Foundation
    1 January 2021
  • Understanding bacterial invasion of the brain: Interactions of Streptococcus pneumoniae with microglia and neurons.
    Åke Wibergs Stiftelse
    1 January 2020
  • Understanding bacterial invasion of the brain
    Loo & Hans Osterman Foundation
    1 November 2019
  • Bacterial Meningitis: Understanding Bacterial Interactions with Microglia and Neurons to Develop New Methods to Boost the Brain Immune System and Prevent Neuronal Damage
    Petrus och Augusta Hedlunds Stiftelse
    1 June 2019
  • Start-up Grant
    StratNeuro
    1 June 2019
  • Block pneumococcal-neuron interaction to protect neurons from bacterial infections
    Clas Groschinsky Foundation
    1 June 2019
  • New therapeutic and prophylactic strategies to cure and prevent bacterial meningitis
    HKH Crown Princess Lovisa's Association for Children Healthcare
    1 January 2019
  • New therapeutic strategies to cure and prevent bacterial meningitis State
    Karolinska Institutet Research Foundations
    1 January 2019
  • Brain cancer and bacterial meningitis: how to prevent bacterial penetration of the blood-brain barrier in patients with brain cancer.
    Åke Wiberg Foundation
    1 January 2019
  • Improving antimicrobial treatments in cancer patients
    Jeansson Foundation
    1 January 2019
  • Faculty-funded Assistant Professor position
    Karolinska Institutet
    3 December 2018
  • Bacterial meningitis: Molecular mechanisms of bacterial entry into the brain across the blood-brain barrier and new therapeutic approaches to block it.
    Petrus and Augusta Hedlund Foundation
    1 June 2018
  • New therapeutic strategies to cure and prevent bacterial meningitis
    Jeansson Foundation
    1 January 2018
  • New therapeutic strategies to cure and prevent bacterial meningitis
    Åke Wiberg Foundation
    1 January 2018
  • Bacterial meningitis: Understanding bacterial invasion of the brain
    Fredrik och Ingrid Thurings Stiftelse
    1 January 2018
  • Show more

Employments

  • Principal Researcher, Department of Neuroscience, Karolinska Institutet, 2023-

Degrees and Education

  • Docent, Karolinska Institutet, 2021

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