Erin Gabriel

About me
Publications
CV
Public outreach and news

About me

* 2004 MA in Economics from McGill University
* 2012 PhD in Biostatistics from University of Washington

Research

I am currently working on both methodological and applied research. I have
several areas of methodological research, including machine learning for
time-to-event outcomes and methods for vaccine research. I am also generally
interested in clinical trial design, causal inference and exact testing. I
assist with statistical expertise in several areas of epidemiological and
clinical research, including Malaria vaccine, Prostate cancer treatment, HIV
and ageing and, IRIS.

Articles

Article: BIOSTATISTICS. 2023;24(4):1017-1030
Cross-direct effects in settings with two mediators
Gabriel EE; Sjolander A; Follmann D; Sachs MC
Article: JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION. 2023;118(544):2446-2453
Sharp Nonparametric Bounds for Decomposition Effects with Two Binary Mediators
Gabriel EE; Sachs MC; Sjolander A
Article: JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION. 2023;118(541):684-692
Nonparametric Bounds for Causal Effects in Imperfect Randomized Experiments
Gabriel EE; Sjolander A; Sachs MC
Article: BIOMETRIKA. 2022;109(4):1101-1116
Sensitivity analysis for unmeasured confounding in the estimation of marginal causal effects
Ciocanea-Teodorescu I; Gabriel EE; Sjolander A
Article: BRITISH JOURNAL OF CANCER. 2022;127(9):1636-1641
Confidence bands in survival analysis
Sachs MC; Brand A; Gabriel EE
Article: JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION. 2022;117(538):939-950
Causal Bounds for Outcome-Dependent Sampling in Observational Studies
Gabriel EE; Sachs MC; Sjolander A
Article: ANNALS OF EPIDEMIOLOGY. 2022;66:1-4
Direct modeling of relative and absolute risks in register data: Mortality risk in sarcoidosis
Gabriel EE; Arkema EV; Sachs MC
Article: JOURNAL OF STATISTICAL SOFTWARE. 2022;102(9):1-34
Event History Regression with Pseudo-Observations: Computational Approaches and an Implementation in R
Sachs MC; Gabriel EE
Article: MICROBIOLOGY SPECTRUM. 2021;9(2):e0054921-e00521
Distinct Metabolic Profile Associated with a Fatal Outcome in COVID-19 Patients during the Early Epidemic in Italy
Saccon E; Bandera A; Sciume M; Mikaeloff F; Lashari AA; Aliberti S; Sachs MC; Billi F; Blasi F; Gabriel EE; Costantino G; De Roberto P; Krishnan S; Gori A; Peyvandi F; Scudeller L; Canetta C; Lorson CL; Valenti L; Singh K; Baldini L; Fracchiolla NS; Neogi U
Article: SEXUAL AND REPRODUCTIVE HEALTHCARE. 2021;29:100622
Alcohol and illicit and non-medical prescription drug use before and during pregnancy in Stockholm, Sweden: A cross-sectional study
Persson A; Lindmark S; Petersson K; Gabriel E; Thorsell M; Lindstrom K; Goransson M; Cardell G; Magnusson A
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2021;190(9):1882-1889
Adjustment for Disease Severity in the Test-Negative Study Design
Ciocanea-Teodorescu I; Nason M; Sjolander A; Gabriel EE
Article: STATISTICS IN MEDICINE. 2021;40(19):4185-4199
Prediction-driven pooled testing methods: Application to HIV treatment monitoring in Rakai, Uganda
Brand A; May S; Hughes JP; Nakigozi G; Reynolds SJ; Gabriel EE
Article: ANNALS OF INTERNAL MEDICINE. 2021;174(8):1118-1125
A Deferred-Vaccination Design to Assess Durability of COVID-19 Vaccine Effect After the Placebo Group Is Vaccinated
Follmann D; Fintzi J; Fay MP; Janes HE; Baden LR; El Sahly HM; Fleming TR; Mehrotra DV; Carpp LN; Juraska M; Benkeser D; Donnell D; Fong Y; Han S; Hirsch I; Huang Y; Huang Y; Hyrien O; Luedtke A; Carone M; Nason M; Vandebosch A; Zhou H; Cho I; Gabriel E; Kublin JG; Cohen MS; Corey L; Gilbert PB; Neuzil KM
Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(7):146221
Pfs230 yields higher malaria transmission-blocking vaccine activity than Pfs25 in humans but not mice
Healy SA; Anderson C; Swihart BJ; Mwakingwe A; Gabriel EE; Decederfelt H; Hobbs CV; Rausch KM; Zhu D; Muratova O; Herrera R; Scaria PV; MacDonald NJ; Lambert LE; Zaidi I; Coelho CH; Renn JP; Wu Y; Narum DL; Duffy PE
Article: TRANSFUSION. 2021;61(2):464-473
Frequent platelet donation is associated with lymphopenia and risk of infections: A nationwide cohort study
Zhao J; Gabriel E; Norda R; Hoglund P; Baden L; Diedrich BA; Marits P; Enoksson SL; Gansner JM; Kaufman R; Dickman PW; Edgren G
Article: JOURNAL OF CAUSAL INFERENCE. 2021;9(1):229-249
On the bias of adjusting for a non-differentially mismeasured discrete confounder
Pena JM; Balgi S; Sjolander A; Gabriel EE
Article: THE JOURNAL OF THE ROYAL STATISTICAL SOCIETY, SERIES C (APPLIED STATISTICS). 2021;70(1):51-65
Stacked inverse probability of censoring weighted bagging: A case study in the InfCareHIV Register
Gonzalez Ginestet P; Kotalik A; Vock DM; Wolfson J; Gabriel EE
Article: BIOMETRICS. 2020;76(4):1053-1063
A unified evaluation of differential vaccine efficacy
Gabriel EE; Sachs MC; Follmann DA; Andersson TM-L
Article: SEXUAL AND REPRODUCTIVE HEALTHCARE. 2020;25:100516
Potentially traumatic events, fear of childbirth and posttraumatic stress disorder during pregnancy in Stockholm, Sweden: A cross-sectional study
Persson A; Lindmark S; Petersson K; Gabriel E; Thorsell M; Lindstrom K; Goransson M; Cardell G; Magnusson A
Article: CLINICAL INFECTIOUS DISEASES. 2020;71(4):1017-1021
Adaptive Viral Load Monitoring Frequency to Facilitate Differentiated Care: A Modeling Study From Rakai, Uganda
Ssempijja V; Nason M; Nakigozi G; Ndyanabo A; Gray R; Wawer M; Chang LW; Gabriel E; Quinn TC; Serwadda D; Reynolds SJ
Article: CLINICAL INFECTIOUS DISEASES. 2020;71(3):652-660
Prospective International Study of Incidence and Predictors of Immune Reconstitution Inflammatory Syndrome and Death in People Living With Human Immunodeficiency Virus and Severe Lymphopenia
Sereti I; Sheikh V; Shaffer D; Phanuphak N; Gabriel E; Wang J; Nason MC; Roby G; Ngeno H; Kirui F; Pau A; Mican JM; Rupert A; Bishop R; Agan B; Chomchey N; Teeratakulpisarn N; Tansuphaswadikul S; Langat D; Kosgei J; French M; Ananworanich J; Sawe F
Article: AMERICAN STATISTICIAN. 2020;74(3):243-248
On Causal Inferences for Personalized Medicine: How Hidden Causal Assumptions Led to Erroneous Causal Claims About the D-Value
Greenland S; Fay MP; Brittain EH; Shih JH; Follmann DA; Gabriel EE; Robins JM
Article: TRIALS. 2020;21(1):579
The ProBio trial: molecular biomarkers for advancing personalized treatment decision in patients with metastatic castration-resistant prostate cancer
Crippa A; De Laere B; Discacciati A; Larsson B; Connor JT; Gabriel EE; Thellenberg C; Janes E; Enblad G; Ullen A; Hjalm-Eriksson M; Oldenburg J; Ost P; Lindberg J; Eklund M; Gronberg H
Article: EPIDEMIOLOGY. 2020;31(3):359-364
Aim for Clinical Utility, Not Just Predictive Accuracy
Sachs MC; Sjolander A; Gabriel EE
Article: BMC PREGNANCY AND CHILDBIRTH. 2020;20(1):225
Social concerns related to HIV status disclosure and participation in the prevention of mother-to-child transmission of HIV care among pregnant women in Kenya
Nordberg B; Gabriel EE; Were E; Kaguiri E; Ekstrom AM; Kagesten A; Rautiainen S
Article: BIOSTATISTICS. 2020;21(2):e33-e46
Predictive cluster level surrogacy in the presence of interference
Gabriel EE; Follmann DA
Article: THE JOURNAL OF THE ROYAL STATISTICAL SOCIETY, SERIES C (APPLIED STATISTICS). 2019;68(5):1431-1446
Ensemble prediction of time-to-event outcomes with competing risks: a case-study of surgical complications in Crohn's disease
Sachs MC; Discacciati A; Everhov AH; Olen O; Gabriel EE
Article: OPEN FORUM INFECTIOUS DISEASES. 2019;6(6):ofz246
A Phase I, Randomized, Controlled Clinical Study of CC-11050 in People Living With HIV With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE)
Boulougoura A; Gabriel E; Laidlaw E; Khetani V; Arakawa K; Higgins J; Rupert A; Gorelick RJ; Lumbard K; Pau A; Poole A; Kibiy A; Kumar P; Sereti I
Article: STATISTICS IN MEDICINE. 2019;38(7):1135-1146
Optimizing and evaluating biomarker combinations as trial-level general surrogates
Gabriel EE; Sachs MC; Daniels MJ; Halloran ME
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1965
Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy
Babu H; Ambikan AT; Gabriel EE; Akusjarvi SS; Palaniappan AN; Sundaraj V; Mupanni NR; Sperk M; Cheedarla N; Sridhar R; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: STATISTICS IN MEDICINE. 2018;37(20):2923-2937
Causal estimands and confidence intervals associated with Wilcoxon-Mann-Whitney tests in randomized experiments
Fay MP; Brittain EH; Shih JH; Follmann DA; Gabriel EE
Article: THE LANCET INFECTIOUS DISEASES. 2018;18(9):969-982
Safety and immunogenicity of Pfs25H-EPA/Alhydrogel, a transmission-blocking vaccine against Plasmodium falciparum: a randomised, double-blind, comparator-controlled, dose-escalation study in healthy Malian adults
Sagara I; Healy SA; Assadou MH; Gabriel EE; Kone M; Sissoko K; Tembine I; Guindo MA; Doucoure M; Niare K; Dolo A; Rausch KM; Narum DL; Jones DL; MacDonald NJ; Zhu D; Mohan R; Muratova O; Baber I; Coulibaly MB; Fay MP; Anderson C; Wu Y; Traore SF; Doumbo OK; Duffy PE
Article: JCI INSIGHT. 2018;3(13):97880
Total body CD4+ T cell dynamics in treated and untreated SIV infection revealed by in vivo imaging.
Di Mascio M; Srinivasula S; Kim I; Duralde G; St Claire A; DeGrange P; St Claire M; Reimann KA; Gabriel EE; Carrasquillo J; Reba RC; Paik C; Lane HC
Article: BIOSTATISTICS. 2018;19(3):307-324
Evaluation and comparison of predictive individual-level general surrogates
Gabriel EE; Sachs MC; Halloran ME
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2018;98(6):1718-1721
Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children
Kasule J; Gabriel EE; Anok A; Neal J; Eastman RT; Penzak S; Newell K; Serwadda D; Duffy PE; Reynolds SJ; Hobbs CV
Article: STATISTICS IN MEDICINE. 2018;37(7):1047-1058
A boundary-optimized rejection region test for the two-sample binomial problem
Gabriel EE; Nason M; Fay MP; Follmann DA
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2018;98(1):67-70
Prevalence of Asymptomatic Parasitemia and Gametocytemia in HIV-Infected Children on Differing Antiretroviral Therapy.
Hobbs CV; Gabriel EE; Kamthunzi P; Tegha G; Tauzie J; Li Y; Ilmet T; Artimovich E; Neal J; Hall T; Parikh S; Kirmse B; Jean-Philippe P; Chen J; Prescott WR; Palumbo P; Duffy PE; Borkowsky W; For The P S Study Team
Article: SCIENTIFIC REPORTS. 2017;7(1):14267
Hemoglobin variants shape the distribution of malaria parasites in human populations and their transmission potential
Goncalves BP; Sagara I; Coulibaly M; Wu Y; Assadou MH; Guindo A; Ellis RD; Diakite M; Gabriel E; Prevots DR; Doumbo OK; Duffy PE
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2017;97(3):719-725
Optimizing Direct Membrane and Direct Skin Feeding Assays for Plasmodium falciparum Transmission-Blocking Vaccine Trials in Bancoumana, Mali.
Coulibaly MB; Gabriel EE; Sinaba Y; Sylla D; Sacko A; Sylla L; Coulibaly B; Hume JCC; Baber I; Assadou MH; Sagara I; Wu Y; Healy SA; Doumbo O; Traore SF; Duffy PE
Article: THE LANCET INFECTIOUS DISEASES. 2017;17(5):498-509
Safety and efficacy of PfSPZ Vaccine against Plasmodium falciparum via direct venous inoculation in healthy malaria-exposed adults in Mali: a randomised, double-blind phase 1 trial.
Sissoko MS; Healy SA; Katile A; Omaswa F; Zaidi I; Gabriel EE; Kamate B; Samake Y; Guindo MA; Dolo A; Niangaly A; Niaré K; Zeguime A; Sissoko K; Diallo H; Thera I; Ding K; Fay MP; O'Connell EM; Nutman TB; Wong-Madden S; Murshedkar T; Ruben AJ; Li M; Abebe Y; Manoj A; Gunasekera A; Chakravarty S; Sim BKL; Billingsley PF; James ER; Walther M; Richie TL; Hoffman SL; Doumbo O; Duffy PE
Article: JCI INSIGHT. 2017;2(4):e85687
HLA-DQ β1 alleles associated with Epstein-Barr virus (EBV) infectivity and EBV gp42 binding to cells.
Li Q; Bu W; Gabriel E; Aguilar F; Hoshino Y; Miyadera H; Hess C; Hornung RL; Roy A; Cohen JI
Article: PLOS ONE. 2017;12(11):e0187912
CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies.
Srinivasula S; Gabriel E; Kim I; DeGrange P; St Claire A; Mallow C; Donahue RE; Paik C; Lane HC; Di Mascio M
Article: BIOMETRICS. 2016;72(4):1046-1054
Comparing Biomarkers as Trial Level General Surrogates
Gabriel EE; Daniels MJ; Halloran ME
Article: STATISTICS IN MEDICINE. 2016;35(24):4398-4412
Who really gets strep sore throat? Confounding and effect modification of a time-varying exposure on recurrent events
Follmann D; Huang C-Y; Gabriel E
Article: BIOSTATISTICS. 2016;17(3):453-467
Augmented trial designs for evaluation of principal surrogates
Gabriel EE; Follmann D
Article: PLOS ONE. 2016;11(12):e0165140
Malaria in HIV-Infected Children Receiving HIV Protease-Inhibitor-Compared with Non-Nucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy, IMPAACT P1068s, Substudy to P1060
Hobbs CV; Gabriel EE; Kamthunzi P; Tegha G; Tauzie J; Petzold E; Barlow-Mosha L; Chi BH; Li Y; Ilmet T; Kirmse B; Neal J; Parikh S; Deygoo N; Philippe PJ; Mofenson L; Prescott W; Chen J; Musoke P; Palumbo P; Duffy PE; Borkowsky W
Article: PLOS ONE. 2016;11(10):e0163144
Safety and Immunogenicityof Pfs25-EPA/Alhydrogel® , a Transmission Blocking Vaccine against Plasmodium falciparum: An Open Label Study in Malaria Naive Adults
Talaat KR; Ellis RD; Hurd J; Hentrich A; Gabriel E; Hynes NA; Rausch KM; Zhu D; Muratova O; Herrera R; Anderson C; Jones D; Aebig J; Brockley S; MacDonald NJ; Wang X; Fay MP; Healy SA; Durbin AP; Narum DL; Wu Y; Duffy PE
Article: PLOS ONE. 2016;11(2):e0147812
Pooled-Peptide Epitope Mapping Strategies Are Efficient and Highly Sensitive: An Evaluation of Methods for Identifying Human T Cell Epitope Specificities in Large-Scale HIV Vaccine Efficacy Trials
Fiore-Gartland A; Manso BA; Friedrich DP; Gabriel EE; Finak G; Moodie Z; Hertz T; De Rosa SC; Frahm N; Gilbert PB; McElrath MJ
Article: JOURNAL OF CAUSAL INFERENCE. 2015;3(2):157-175
Surrogate Endpoint Evaluation: Principal Stratification Criteria and the Prentice Definition.
Gilbert PB; Gabriel EE; Huang Y; Chan ISF
Article: STATISTICS IN MEDICINE. 2015;34(3):381-395
Comparing and combining biomarkers as principle surrogates for time-to-event clinical endpoints
Gabriel EE; Sachs MC; Gilbert PB
Article: JOURNAL OF INFECTIOUS DISEASES. 2014;210(10):1573-1581
Fold Rise in Antibody Titers by Measured by Glycoprotein-Based Enzyme-Linked Immunosorbent Assay Is an Excellent Correlate of Protection for a Herpes Zoster Vaccine, Demonstrated via the Vaccine Efficacy Curve
Gilbert PB; Gabriel EE; Miao X; Li X; Su S-C; Parrino J; Chan ISF
Article: BIOSTATISTICS. 2014;15(2):251-265
Evaluating principal surrogate endpoints with time-to-event data accounting for time-varying treatment efficacy
Gabriel EE; Gilbert PB
Article: PLOS ONE. 2013;8(5):e64405
Superior Control of HIV-1 Replication by CD8+T Cells Targeting Conserved Epitopes: Implications for HIV Vaccine Design
Kunwar P; Hawkins N; Dinges WL; Liu Y; Gabriel EE; Swan DA; Stevens CE; Maenza J; Collier AC; Mullins JI; Hertz T; Yu X; Horton H
Article: BLOOD. 2012;120(14):2836-2842
Association of Fcγ receptor IIIa genotype with the rate of HIV infection after gp120 vaccination
Forthal DN; Gabriel EE; Wang A; Landucci G; Phan TB
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2012;382(1-2):117-128
Optimization and qualification of a multiplex bead array to assess cytokine and chemokine production by vaccine-specific cells
Defawe OD; Fong Y; Vasilyeva E; Pickett M; Carter DK; Gabriel E; Rerks-Ngarm S; Nitayaphan S; Frahm N; McElrath MJ; De Rosa SC
Article: PLOS ONE. 2012;7(8):e43396
MRKAd5 HIV-1 Gag/Pol/Nef Vaccine-Induced T-Cell Responses Inadequately Predict Distance of Breakthrough HIV-1 Sequences to the Vaccine or Viral Load
Janes H; Frahm N; DeCamp A; Rolland M; Gabriel E; Wolfson J; Hertz T; Kallas E; Goepfert P; Friedrich DP; Corey L; Mullins JI; McElrath MJ; Gilbert P
Article: STATISTICAL COMMUNICATIONS IN INFECTIOUS DISEASES. 2011;3(1):1037
A Sequential Phase 2b Trial Design for Evaluating Vaccine Efficacy and Immune Correlates for Multiple HIV Vaccine Regimens.
Gilbert PB; Grove D; Gabriel E; Huang Y; Gray G; Hammer SM; Buchbinder SP; Kublin J; Corey L; Self SG
Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2010;304(13):1455-1464
Out-of-Hospital Hypertonic Resuscitation Following Severe Traumatic Brain Injury A Randomized Controlled Trial
Bulger EM; May S; Brasel KJ; Schreiber M; Kerby JD; Tisherman SA; Newgard C; Slutsky A; Coimbra R; Emerson S; Minei JP; Bardarson B; Kudenchuk P; Baker A; Christenson J; Idris A; Davis D; Fabian TC; Aufderheide TP; Callaway C; Williams C; Banek J; Vaillancourt C; van Heest R; Sopko G; Hata JS; Hoyt DB
Article: RESUSCITATION. 2010;81(2):155-162
Survival Increases with CPR by Emergency Medical Services before defibrillation of out-of-hospital ventricular fibrillation or ventricular tachycardia: Observations from the Resuscitation Outcomes Consortium
Bradley SM; Gabriel EE; Aufderheide TP; Barnes R; Christenson J; Davis DP; Stiell IG; Nichol G
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All other publications

Letter: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2021;190(10):2231-2232
ON THE USE OF NONPARAMETRIC BOUNDS FOR CAUSAL EFFECTS IN NULL RANDOMIZED TRIALS
Gabriel EE; Sachs MC
Preprint: MEDRXIV. 2020;MEDRXIV
Assessing Durability of Vaccine Effect Following Blinded Crossover in COVID-19 Vaccine Efficacy Trials.
Follmann D; Fintzi J; Fay MP; Janes HE; Baden L; Sahly HE; Fleming TR; Mehrotra DV; Carpp LN; Juraska M; Benkeser D; Donnell D; Fong Y; Han S; Hirsch I; Huang Y; Huang Y; Hyrien O; Luedtke A; Carone M; Nason M; Vandebosch A; Zhou H; Cho I; Gabriel E; Kublin JG; Cohen MS; Corey L; Gilbert PB; Neuzil KM
Letter: STATISTICS IN MEDICINE. 2018;37(14):2303-2306
Response to letter by Antonio Martin Andres on "A boundary-optimized rejection region test for the two-sample binomial problem"
Gabriel EE; Nason M; Fay MP; Follmann D
Editorial comment: R JOURNAL. 2016;8(2):277-292
An Introduction to Principal Surrogate Evaluation with the pseval Package
Sachs MC; Gabriel EE
Review: VACCINE. 2016;34(48):5863-5870
Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: A systematic review of methods and case study
Brickley EB; Coulibaly M; Gabriel EE; Healy SA; Hume JCC; Sagara I; Traore SF; Doumbo O; Duffy PE
Letter: JOURNAL OF INFECTIOUS DISEASES. 2015;212(9):1521-1523
Ifit1 Protects Against Lipopolysaccharide and D-galactosamine-Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway Reply
Gilbert PB; Gabriel EE; Hudgens MG; Miao X; Li X; Su S-C; Parrino J; Chan ISF
Meeting abstract: RETROVIROLOGY. 2012;9:p260
Breadth or conservation score (CS): which is more important for HIV-1 T cell based vaccine immunogen design?
Kunwar P; Hawkins NR; Yu X; Liu Y; Collier A; Gabriel EE; Hertz T; Horton H

Employments

Affiliated to Research, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2020

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