Erika Bereczki

About me
Publications
CV
Public outreach and news

About me

I have PhD in theoretical medical sciences from the University of Szeged
where I graduated in 2007.

Research

My research interest can be broadly described as dementia research focusing
on understanding the mechanism and consequences of dementia, improving
differential diagnosis and predicting cognitive decline in Alzheimer's
disease and Lewy body dementias with particular interest in synaptic proteins
and their role in dementia progression. Lately, humbled by the impact of
SARS-Cov-2 I have joined the National Pandemic center of KI as a research
specialist contributing to the increased diagnostic and sequencing capacity
of Covid-19 in Sweden, aiming to understand the needs and means of responding
to future pandemics.

Articles

Article: MOLECULAR PSYCHIATRY. 2023;28(9):3966-3981
Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models
Naia L; Shimozawa M; Bereczki E; Li X; Liu J; Jiang R; Giraud R; Leal NS; Pinho CM; Berger E; Falk VL; Dentoni G; Ankarcrona M; Nilsson P
Article: BIOLOGY. 2023;12(6):805
The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer's Disease in App^NL-G-F Knock-In Mice
Medina-Vera D; Zhao H; Bereczki E; Rosell-Valle C; Shimozawa M; Chen G; de Fonseca FR; Nilsson P; Tambaro S
Article: BRAIN COMMUNICATIONS. 2022;5(1):fcad001
Translational potential of synaptic alterations in Alzheimer's disease patients and amyloid precursor protein knock-in mice
Medina-Vera D; Enache D; Tambaro S; Abuhashish E; Rosell-Valle C; Winblad B; de Fonseca FR; Bereczki E; Nilsson P
Article: MOLECULAR PSYCHIATRY. 2022;27(8):3247-3261
Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia
Matlik K; Garton DR; Montano-Rodriguez AR; Olfat S; Eren F; Casserly L; Damdimopoulos A; Panhelainen A; Porokuokka LL; Kopra JJ; Turconi G; Schweizer N; Bereczki E; Piehl F; Engberg G; Cervenka S; Piepponen TP; Zhang F-P; Sipila P; Jakobsson J; Sellgren CM; Erhardt S; Andressoo J-O
Article: SCIENTIFIC DATA. 2021;8(1):312
Insights into the changes in the proteome of Alzheimer disease elucidated by a meta-analysis
Haytural H; Benfeitas R; Schedin-Weiss S; Bereczki E; Rezeli M; Unwin RD; Wang X; Dammer EB; Johnson ECB; Seyfried NT; Winblad B; Tijms BM; Visser PJ; Frykman S; Tjernberg LO
Article: BRAIN COMMUNICATIONS. 2021;3(2):fcab049
Presynaptic accumulation of α-synuclein causes synaptopathy and progressive neurodegeneration in Drosophila
Bridi JC; Bereczki E; Smith SK; Pocas GM; Kottler B; Domingos PM; Elliott CJ; Aarsland D; Hirth F
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2020;77(3):1143-1155
Increased Cerebrospinal Fluid Concentration of ZnT3 Is Associated with Cognitive Impairment in Alzheimer's Disease
Enache D; Pereira JB; Jelic V; Winblad B; Nilsson P; Aarsland D; Bereczki E
Article: BRAIN. 2018;141(2):582-595
Synaptic markers of cognitive decline in neurodegenerative diseases: a proteomic approach
Bereczki E; Branca RM; Francis PT; Pereira JB; Baek J-H; Hortobagyi T; Winblad B; Ballard C; Lehtio J; Aarsland D
Article: ORVOSI HETILAP. 2017;158(17):643-652
[Clinical and neuropathological characteristics of dementia with Lewy bodies].
Bencze J; Simon V; Bereczki E; Majer R; Varkoly G; Murnyák B; Kálmán J; Hortobágyi T
Article: NPJ PARKINSON'S DISEASE. 2017;3:7
Synaptic proteins in CSF relate to Parkinson's disease stage markers
Bereczki E; Bogstedt A; Hoglund K; Tsitsi P; Brodin L; Ballard C; Svenningsson P; Aarsland D
Article: ALZHEIMER'S AND DEMENTIA. 2016;12(11):1149-1158
Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia
Bereczki E; Francis PT; Howlett D; Pereira JB; Hoglund K; Bogstedt A; Cedazo-Minguez A; Baek J-H; Hortobagyi T; Attems J; Ballard C; Aarsland D
Article: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2016;42(4):352-365
Unfolded protein response is activated in Lewy body dementias
Baek J-H; Whitfield D; Howlett D; Francis P; Bereczki E; Ballard C; Hortobagyi T; Attems J; Aarsland D
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1853(7):1646-1657
mTor mediates tau localization and secretion: Implication for Alzheimer's disease
Tang Z; Ioja E; Bereczki E; Hultenby K; Li C; Guan Z; Winblad B; Pei J-J
Article: NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY, AND MEDICINE. 2015;11(2):421-430
Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice
Ordonez-Gutierrez L; Re F; Bereczki E; Ioja E; Gregori M; Andersen AJ; Anton M; Moghimi SM; Pei J-J; Masserini M; Wandosell F
Article: METABOLIC BRAIN DISEASE. 2014;29(3):729-736
mTOR-mediated hyperphosphorylation of tau in the hippocampus is involved in cognitive deficits in streptozotocin-induced diabetic mice
Wang S; Zhou S-L; Min F-Y; Ma J-J; Shi X-J; Bereczki E; Wu J
Article: JOURNAL OF PROTEOME RESEARCH. 2014;13(5):2433-2444
mTor Is a Signaling Hub in Cell Survival: A Mass-Spectrometry-Based Proteomics Investigation
Tang Z; Baykal AT; Gao H; Quezada HC; Zhang H; Bereczki E; Serhatli M; Baykal B; Acioglu C; Wang S; Ioja E; Ji X; Zhang Y; Guan Z; Winblad B; Pei J-J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(22):15556-15570
Mammalian Target of Rapamycin (mTor) Mediates Tau Protein Dyshomeostasis IMPLICATION FOR ALZHEIMER DISEASE
Tang Z; Bereczki E; Zhang H; Wang S; Li C; Ji X; Branca RM; Lehtio J; Guan Z; Filipcik P; Xu S; Winblad B; Pei J-J
Article: PLOS ONE. 2012;7(9):e46007
Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice
Lenart N; Szegedi V; Juhasz G; Kasztner A; Horvath J; Bereczki E; Toth ME; Penke B; Santha M
Article: NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY, AND MEDICINE. 2011;7(5):560-571
Liposomes functionalized with acidic lipids rescue Aβ-induced toxicity in murine neuroblastoma cells
Bereczki E; Re F; Masserini ME; Winblad B; Pei JJ
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2011;89(8):1267-1275
Interplay Between Glycogen Synthase Kinase-3β and Tau in the Cerebellum of Hsp27 Transgenic Mouse
Wang S; Toth ME; Bereczki E; Santha M; Guan Z-Z; Winblad B; Pei J-J
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2010;48(4):649-652
Biglycan protects cardiomyocytes against hypoxia/reoxygenation injury: Role of nitric oxide
Csont T; Gorbe A; Bereczki E; Szunyog A; Aypar E; Toth ME; Varga ZV; Csonka C; Fulop F; Santha M; Ferdinandy P
Article: EXPERIMENTAL EYE RESEARCH. 2009;89(2):178-186
Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes
Sallo FB; Bereczki E; Csont T; Luthert PJ; Munro P; Ferdinandy P; Santha M; Lengyel I
Article: HEPATOLOGY. 2009;50(1):77-84
Apolipoprotein B100 Acts as a Molecular Link Between Lipid-Induced Endoplasmic Reticulum Stress and Hepatic Insulin Resistance
Su Q; Tsai J; Xu E; Qiu W; Bereczki E; Santha M; Adeli K
Article: LIFE SCIENCES. 2009;84(25-26):935-939
Capillary injury in the ischemic brain of hyperlipidemic, apolipoprotein B-100 transgenic mice
Suele Z; Mracsko E; Bereczki E; Miklos S; Csont T; Ferdinandy P; Ferenc B; Farkas E
Article: NEUROCHEMISTRY INTERNATIONAL. 2008;53(6-8):309-316
CB₂ cannabinoid receptor antagonist SR144528 decreases mu-opioid receptor expression and activation in mouse brainstem: Role of CB₂ receptor in pain
Paldy E; Bereczki E; Santha M; Wenger T; Borsodi A; Zimmer A; Benyhe S
Article: JOURNAL OF PROTEOME RESEARCH. 2008;7(6):2246-2252
Overexpression of human apolipoprotein B-100 induces severe neurodegeneration in transgenic mice
Bereczki E; Bernat G; Csont T; Ferdinandy P; Scheich H; Santha M
Article: NEUROCHEMISTRY INTERNATIONAL. 2008;52(1-2):321-328
Noladin ether, a putative endocannabinoid, inhibits μ-opioid receptor activation via CB2 cannabinoid receptors
Paldyova E; Bereczki E; Santha M; Wenger T; Borsodi A; Benyhe S
Article: CONNECTIVE TISSUE RESEARCH. 2008;49(3-4):129-132
The role of biglycan in the heart
Bereczki E; Santha M
Article: CARDIOVASCULAR RESEARCH (CVR). 2007;76(1):100-109
Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice
Csont T; Bereczki E; Bencsik P; Fodor G; Goerbe A; Zvara A; Csonka C; Puskas LG; Santha M; Ferdinandy P
Article: JOURNAL OF PROTEOME RESEARCH. 2007;6(2):854-861
Overexpression of biglycan in the heart of transgenic mice:: An antibody microarray study
Bereczki E; Gonda S; Csont T; Korpos E; Zvara A; Ferdinandy P; Santha M
Article: BIOLOGIA FUTURA. 2007;58:113-129
Altered gene expression and functional activity of opioid receptors in the cerebellum of CB₁ cannabinoid receptor knockout mice after acute treatments with cannabinoids
Paldyova E; Bereczki E; Santha M; Wenger T; Borsodi A; Benyhe S
Article: NEUROCHEMISTRY INTERNATIONAL. 2007;50(1):1-4
APP mRNA splicing is upregulated in the brain of biglycan transgenic mice
Bjelik A; Pakaski M; Bereczki E; Gonda S; Juhasz A; Rimanoczy A; Zana M; Janka Z; Santha M; Kalman J
Article: NEUROCHEMISTRY INTERNATIONAL. 2006;49(4):393-400
Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis
Bjelik A; Bereczki E; Gonda S; Juhasz A; Rimanoczy A; Zana M; Csont T; Pakaski M; Boda K; Ferdinandy P; Dux L; Janka Z; Santha M; Kalman J
Article: BIOCHIMIE. 2004;86(11):817-824
Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain
Puskás LG; Bereczki E; Sántha M; Vigh L; Csanádi G; Spener F; Ferdinandy P; Onochy A; Kitajka K
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All other publications

Corrigendum: BRAIN. 2019;142(6):e24
Corrigendum.
Review: CURRENT TOPICS IN MEDICINAL CHEMISTRY. 2015;15(22):2267-2276
Comparison of Various Types of Ligand Decorated Nanoliposomes for their Ability to Inhibit Amyloid Aggregation and to Reverse Amyloid Cytotoxicity
Markoutsa E; Mourtas S; Bereczki E; Zona C; La Ferla B; Nicotra F; Flores O; Pei J-J; Antimisiaris SG
Review: JOURNAL OF ALZHEIMER'S DISEASE. 2013;37(3):495-505
Dysregulated mTOR-Dependent Signaling in Neurodegeneration or Carcinogenesis: Implication for Alzheimer's Disease and Brain Tumors
Wang S; Wu J; Nie S-D; Bereczki E; Pei J-J

Employments

Affiliated to Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 2023-2025
Affiliated to Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2024-2024
Research Specialist, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2022-2024

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