Erik Holmgren

Publications
Public outreach and news

Articles

Article: SCIENCE ADVANCES. 2023;9(20):eadg3032
Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis
Thomas OG; Bronge M; Tengvall K; Akpinar B; Nilsson OB; Holmgren E; Hessa T; Gafvelin G; Khademi M; Alfredsson L; Martin R; Guerreiro-Cacais AO; Groenlund H; Olsson T; Kockum I
Article: SCIENCE ADVANCES. 2022;8(17):eabn1823
Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis
Bronge M; Hogelin KA; Thomas OG; Ruhrmann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Zeitelhofer M; Holmgren E; Linnerbauer M; Adzemovic MZ; Hellstrom C; Jelcic I; Liu H; Nilsson P; Hillert J; Brundin L; Fink K; Kockum I; Tengvall K; Martin R; Tegel H; Graslund T; Al Nimer F; Guerreiro-Cacais AO; Khademi M; Gafvelin G; Olsson T; Gronlund H
Article: JOURNAL OF AUTOIMMUNITY. 2019;102:38-49
Myelin oligodendrocyte glycoprotein revisited-sensitive detection of MOG-specific T-cells in multiple sclerosis
Bronge M; Ruhrrnann S; Carvalho-Queiroz C; Nilsson OB; Kaiser A; Holmgren E; Macrini C; Winkhneier S; Meinl E; Brundin L; Khademi M; Olsson T; Gafvelin G; Gronlund H
Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74(8):1472-1479
Allergens in dog extracts: Implication for diagnosis and treatment
Wintersand A; Asplund K; Binnmyr J; Holmgren E; Nilsson OB; Gafvelin G; Gronlund H
Article: METHODSX. 2019;6:1635-1641
Sensitive detection of antigen-specific T-cells using bead-bound antigen for in vitro re-stimulation
Bronge M; Kaiser A; Carvalho-Queiroz C; Nilsson OB; Ruhrmann S; Holmgren E; Olsson T; Gafvelin G; Gronlund H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(8):2188-2193
Anoctamin 2 identified as an autoimmune target in multiple sclerosis
Ayoglu B; Mitsios N; Kockum I; Khademi M; Zandian A; Sjoberg R; Forsstrom B; Bredenberg J; Bomfim IL; Holmgren E; Gronlund H; Guerreiro-Cacais AO; Abdelmagid N; Uhlen M; Waterboer T; Alfredsson L; Mulder J; Schwenk JM; Olsson T; Nilsson P
Article: PLOS ONE. 2014;9(10):e111041
Designing a Multimer Allergen for Diagnosis and Immunotherapy of Dog Allergic Patients
Nilsson OB; Neimert-Andersson T; Bronge M; Grundstrom J; Sarma R; Uchtenhagen H; Kikhney A; Sandalova T; Holmgren E; Svergun D; Achour A; van Hage M; Gronlund H
Article: PROTEIN EXPRESSION AND PURIFICATION. 2006;46(2):321-331
Production of a truncated soluble human semicarbazide-sensitive amine oxidase mediated by a GST-fusion protein secreted from HEK293 cells
Öhman J; Jakobsson E; Kdllström U; Elmblad A; Ansari A; Kalderén C; Robertson E; Danielsson E; Gustavsson AL; Varadi A; Ekbloin J; Holmgren E; Doverskog M; Abrahmsén L; Nilsson J
Article: GENE. 2001;273(2):259-265
Cooperative effects by the initiation codon and its flanking regions on translation initiation
Stenström CM; Holmgren E; Isaksson LA
Journal article: THE FEBS JOURNAL. 1994;220(3):893-900
TRANSLOCATION AND PROCESSING OF VARIOUS HUMAN PARATHYROID-HORMONE PEPTIDES IN ESCHERICHIA-COLI ARE DIFFERENTIALLY AFFECTED BY PROTEIN-A-SIGNAL-SEQUENCE MUTATIONS
KAREEM BN; ROKKONES E; HOGSET A; HOLMGREN E; GAUTVIK KM
Journal article: JOURNAL OF MOLECULAR BIOLOGY. 1993;229(3):656-670
COEXISTING STRUCTURES OF AN MESSENGER-RNA STABILITY DETERMINANT - THE 5' REGION OF THE ESCHERICHIA-COLI AND SERRATIA-MARCESCENS-OMPA MESSENGER-RNA
ROSENBAUM V; KLAHN T; LUNDBERG U; HOLMGREN E; VONGABAIN A; RIESNER D
Journal article: JOURNAL OF BIOTECHNOLOGY. 1992;25(3):269-287
FUSIONS TO THE 5' END OF A GENE ENCODING A 2-DOMAIN ANALOG OF STAPHYLOCOCCAL PROTEIN-A
RONDAHL H; NILSSON B; HOLMGREN E
Journal article: ANALYTICAL BIOCHEMISTRY. 1992;204(1):26-33
A method for the evaluation of the efficiency of signal sequences for secretion and correct N-terminal processing of human parathyroid hormone produced in Escherichia coli.
Kareem BN; Rokkones E; Høgset A; Holmgren E; Gautvik KM
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1990;265(13):7338-7344
EXPRESSION AND CHARACTERIZATION OF A RECOMBINANT HUMAN PARATHYROID-HORMONE SECRETED BY ESCHERICHIA-COLI EMPLOYING THE STAPHYLOCOCCAL PROTEIN-A PROMOTER AND SIGNAL SEQUENCE
HOGSET A; BLINGSMO OR; SAETHER O; GAUTVIK VT; HOLMGREN E; HARTMANIS M; JOSEPHSON S; GABRIELSEN OS; GORDELADZE JO; ALESTROM P; GAUTVIK KM
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1989;86(12):4367-4371
DUAL AFFINITY FUSION APPROACH AND ITS USE TO EXPRESS RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-II
HAMMARBERG B; NYGREN PA; HOLMGREN E; ELMBLAD A; TALLY M; HELLMAN U; MOKS T; UHLEN M
Journal article: JOURNAL OF BACTERIOLOGY. 1989;171(6):3471-3478
RHIZOBIUM-MELILOTI ANTHRANILATE SYNTHASE GENE - CLONING, SEQUENCE, AND EXPRESSION IN ESCHERICHIA-COLI
BAE YM; HOLMGREN E; CRAWFORD IP
Journal article: BIOCHEMISTRY. 1987;26(17):5239-5244
EXPRESSION OF HUMAN INSULIN-LIKE GROWTH FACTOR-I IN BACTERIA - USE OF OPTIMIZED GENE FUSION VECTORS TO FACILITATE PROTEIN-PURIFICATION
MOKS T; ABRAHMSEN L; HOLMGREN E; BILICH M; OLSSON A; UHLEN M; POHL G; STERKY C; HULTBERG H; JOSEPHSON S; HOLMGREN A; JORNVALL H; NILSSON B
Journal article: PROTEIN ENGINEERING, DESIGN AND SELECTION. 1987;1(2):107-113
A SYNTHETIC IGG-BINDING DOMAIN BASED ON STAPHYLOCOCCAL PROTEIN-A
NILSSON B; MOKS T; JANSSON B; ABRAHMSEN L; ELMBLAD A; HOLMGREN E; HENRICHSON C; JONES TA; UHLEN M
Journal article: GENE. 1987;58(1):87-97
A GENE FUSION SYSTEM FOR GENERATING ANTIBODIES AGAINST SHORT PEPTIDES
LOWENADLER B; JANSSON B; PALEUS S; HOLMGREN E; NILSSON B; MOKS T; PALM G; JOSEPHSON S; PHILIPSON L; UHLEN M
Journal article: EMBO JOURNAL. 1986;5(9):2393-2398
PRODUCTION OF SPECIFIC ANTIBODIES AGAINST PROTEIN-A FUSION PROTEINS
LOWENADLER B; NILSSON B; ABRAHMSEN L; MOKS T; LJUNGQVIST L; HOLMGREN E; PALEUS S; JOSEPHSON S; PHILIPSON L; UHLEN M
Journal article: NUCLEIC ACIDS RESEARCH (NAR). 1985;13(4):1151-1162
EFFICIENT SECRETION AND PURIFICATION OF HUMAN INSULIN-LIKE GROWTH FACTOR-I WITH A GENE FUSION VECTOR IN STAPHYLOCOCCI
NILSSON B; HOLMGREN E; JOSEPHSON S; GATENBECK S; PHILIPSON L; UHLEN M
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1983;80(2):349-352
ISOLATION OF CDNA SEQUENCES CODING FOR A PART OF HUMAN-TISSUE PLASMINOGEN-ACTIVATOR
EDLUND T; NY T; RANBY M; HEDEN LO; PALM G; HOLMGREN E; JOSEPHSON S
Journal article: JOURNAL OF BACTERIOLOGY. 1982;149(3):1135-1137
REGULATION OF TRYPTOPHAN GENES IN RHIZOBIUM-LEGUMINOSARUM
HOLMGREN E; CRAWFORD IP
Journal article: JOURNAL OF BACTERIOLOGY. 1979;138(2):370-376
CHARACTERIZATION OF A SUCCINATE-DEHYDROGENASE COMPLEX SOLUBILIZED FROM THE CYTOPLASMIC MEMBRANE OF BACILLUS-SUBTILIS WITH THE NON-IONIC DETERGENT TRITON X-100
HEDERSTEDT L; HOLMGREN E; RUTBERG L
Journal article: JOURNAL OF BACTERIOLOGY. 1979;138(2):377-382
ROLE OF HEME IN SYNTHESIS AND MEMBRANE-BINDING OF SUCCINIC-DEHYDROGENASE IN BACILLUS-SUBTILIS
HOLMGREN E; HEDERSTEDT L; RUTBERG L
Journal article: JOURNAL OF BACTERIOLOGY. 1978;136(1):304-311
CHARACTERIZATION OF SUCCINIC-DEHYDROGENASE MUTANTS OF BACILLUS-SUBTILIS BY CROSSED IMMUNOELECTROPHORESIS
RUTBERG B; HEDERSTEDT L; HOLMGREN E; RUTBERG L
Journal article: FEMS MICROBIOLOGY LETTERS. 1978;3(6):327-329
MUTANT OF BACILLUS-SUBTILIS WITH TEMPERATURE-SENSITIVE SYNTHESIS OF FATTY-ACIDS
HOLMGREN E
Journal article: JOURNAL OF BACTERIOLOGY. 1977;132(2):473-484
BACILLUS-SUBTILIS MUTANT WITH TEMPERATURE-SENSITIVE NET SYNTHESIS OF PHOSPHATIDYLETHANOLAMINE
LINDGREN V; HOLMGREN E; RUTBERG L
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Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):234-235
Investigating the T cell response to Anoctamin-2 and Epstein-Barr virus nuclear antigen 1 in multiple sclerosis using antigen-coupled beads
Thomas O; Bronge M; Hogelin KA; Carvalho-Queiroz C; Ruhrmann S; Nilsson O; Holmgren E; Graslund T; Martin R; Gafvelin G; Olsson T; Gronlund H
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):233-234
Re-visiting αβ-crystallin: EBNA1 antibody crossreactivity and CRYAB-specific T cell responses in multiple sclerosis
Thomas O; Bronge M; Tengvall K; Gyllenberg A; Hellstrom C; Holmgren E; Graslund T; Khademi M; Martin R; Nilsson P; Gafvelin G; Gronlund H; Olsson T; Kockum I
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2021;27(2_SUPPL):50-51
Comprehensive autoantigen panel to determine individual immune profiles in multiple sclerosis
Thomas O; Bronge M; Hogelin KA; Carvalho-Querioz C; Nilsson O; Kaiser A; Holmgren E; Graslund T; Gafvelin G; Olsson T; Gronlund H
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:221
Sensitive detection of rare myelin oligodendrocyte glycoprotein-specific T-cells in multiple sclerosis
Bronge M; Ruhrmann S; Carvalho-Queiroz C; Nilsson O; Kaiser A; Holmgren E; Macrini C; Winklmeier S; Meinl E; Brundin L; Khademi M; Olsson T; Gafvelin G; Groenlund H
Conference publication: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71:612
The concentration and composition of dog allergens in dog dander extracts from different vendors
Whiteman A; Binnmyr J; Holmgren E; Gafvelin G; Gronlund H
Published conference paper: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2000;1459(2-3):449-455
Fusion protein approach to improve the crystal quality of cytochrome bo₃ ubiquinol oxidase from Escherichia coli
Byrne B; Abramson J; Jansson M; Holmgren E; Iwata S
Book chapter: THE BIOLOGY OF THE INTERFERON SYSTEM 1986. 1987;p. 11-18
Differential Structures and Activities of Three IFN α2 Variants Departing Only at Two Amino Acid Positions
v. Gabain A; Ohlsson M; Holmgren E; Josephsson S; Alkan SS; Lundgren E

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