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About me

I am employed as a senior researcher in the cognitive neuroscience of aging at the Aging Research Center. My research interests cover a range of topics related to cognitive aging, including (a) cognitive functioning in preclinical dementia, (b) the effect of vascular factors on cognitive performance in normal aging and dementia, (c) structural brain correlates to old-age cognitive performance, (d) genetic effects on brain structure and cognition, (e) correlates to olfactory memory in aging, and (f) cognitive decline in close proximity to death.

In parallel with my research activities, I am the scientific coordinator of the collection of cognitive data in the Swedish National study on Aging and Care in Kungsholmen (SNAC-K) and regularly teaches classes in cognitive aging, psychology, and statistics.

Education

Associate professor in Psychology 2018, Karolinska Institutet

PhD in Medical Science 2006, Karolinska Institutet

MSc in Psychology 1998, Uppsala University

Licensed psychologist 2003

Publications

Effects of between-person differences and within-person changes in symptoms of anxiety and depression on older age cognitive performance
Laukka Ej, Dykiert D, Allerhand M, Starr Jm, Deary Ij
Psychological medicine 2018;48(8):1350-1358

Anticholinergic drug use is associated with episodic memory decline in older adults without dementia
Papenberg G, Bäckman L, Fratiglioni L, Laukka Ej, Fastbom J, Johnell K
Neurobiology of aging 2017;55():27-32

Cognitive and Physical Function in Relation to the Risk of Injurious Falls in Older Adults: A Population-Based Study
Welmer Ak, Rizzuto D, Laukka Ej, Johnell K, Fratiglioni L
The journals of gerontology. Series A, Biological sciences and medical sciences 2017;72(5):669-675

Cognitive performance in unipolar old-age depression: a longitudinal study
Pantzar A, Atti Ar, Fratiglioni L, Fastbom J, Bäckman L, Laukka Ej
International journal of geriatric psychiatry 2017;32(6):675-684

Differential Effects of Encoding Instructions on Brain Activity Patterns of Item and Associative Memory
Becker N, Kalpouzos G, Persson J, Laukka Ej, Brehmer Y
Journal of cognitive neuroscience 2017;29(3):545-559

Dopamine Receptor Genes Modulate Associative Memory in Old Age
Papenberg G, Becker N, Ferencz B, Naveh-benjamin M, Laukka Ej, Bäckman L, et al
Journal of cognitive neuroscience 2017;29(2):245-253

Mixed brain lesions mediate the association between cardiovascular risk burden and cognitive decline in old age: A population-based study
Wang R, Fratiglioni L, Kalpouzos G, Lövdén M, Laukka Ej, Bronge L, et al
Alzheimer's & dementia : the journal of the Alzheimer's Association 2017;13(3):247-256

Phantom Smells: Prevalence and Correlates in a Population-Based Sample of Older Adults
Sjölund S, Larsson M, Olofsson Jk, Seubert J, Laukka Ej
Chemical senses 2017;42(4):309-318

Prevalence and Correlates of Olfactory Dysfunction in Old Age: A Population-Based Study
Seubert J, Laukka Ej, Rizzuto D, Hummel T, Fratiglioni L, Bäckman L, et al
The journals of gerontology. Series A, Biological sciences and medical sciences 2017;72(8):1072-1079

The Vascular Impairment of Cognition Classification Consensus Study
Vicccs Group, Skrobot Oa, O'brien J, Black S, Chen C, Decarli C, et al
Alzheimer's & dementia : the journal of the Alzheimer's Association 2017;13(6):624-633

Association of Vitamin B12, Folate, and Sulfur Amino Acids With Brain Magnetic Resonance Imaging Measures in Older Adults: A Longitudinal Population-Based Study
Hooshmand B, Mangialasche F, Kalpouzos G, Solomon A, Kåreholt I, Smith Ad, et al
JAMA psychiatry 2016;73(6):606-13

Early Cognitive Deficits in Type 2 Diabetes: A Population-Based Study
Marseglia A, Fratiglioni L, Laukka Ej, Santoni G, Pedersen Nl, Bäckman L, et al
Journal of Alzheimer's disease : JAD 2016;53(3):1069-78

Olfactory memory in the old and very old: relations to episodic and semantic memory and APOE genotype
Larsson M, Hedner M, Papenberg G, Seubert J, Bäckman L, Laukka Ej
Neurobiology of aging 2016;38():118-126

Three-year changes in leisure activities are associated with concurrent changes in white matter microstructure and perceptual speed in individuals aged 80 years and older
Köhncke Y, Laukka Ej, Brehmer Y, Kalpouzos G, Li Tq, Fratiglioni L, et al
Neurobiology of aging 2016;41():173-186

Effects of psychiatric history on cognitive performance in old-age depression
Pantzar A, Atti Ar, Bäckman L, Laukka Ej
Frontiers in psychology 2015;6():865-

Effects of vascular risk factors and APOE ε4 on white matter integrity and cognitive decline
Wang R, Fratiglioni L, Laukka Ej, Lövdén M, Kalpouzos G, Keller L, et al
Neurology 2015;84(11):1128-35

Magnified effects of the COMT gene on white-matter microstructure in very old age
Papenberg G, Lövdén M, Laukka Ej, Kalpouzos G, Keller L, Graff C, et al
Brain structure & function 2015;220(5):2927-38

Microstructural White Matter Properties Mediate the Association between APOE and Perceptual Speed in Very Old Persons without Dementia
Laukka Ej, Lövdén M, Kalpouzos G, Papenberg G, Keller L, Graff C, et al
PloS one 2015;10(8):e0134766-

Structural brain correlates of associative memory in older adults
Becker N, Laukka Ej, Kalpouzos G, Naveh-benjamin M, Bäckman L, Brehmer Y
NeuroImage 2015;118():146-53

Changes in perceptual speed and white matter microstructure in the corticospinal tract are associated in very old age
Lövdén M, Köhncke Y, Laukka Ej, Kalpouzos G, Salami A, Li Tq, et al
NeuroImage 2014;102 Pt 2():520-30

Cognitive deficits in unipolar old-age depression: a population-based study
Pantzar A, Laukka Ej, Atti Ar, Fastbom J, Fratiglioni L, Bäckman L
Psychological medicine 2014;44(5):937-47

Interactive effects of KIBRA and CLSTN2 polymorphisms on episodic memory in old-age unipolar depression
Pantzar A, Laukka Ej, Atti Ar, Papenberg G, Keller L, Graff C, et al
Neuropsychologia 2014;62():137-42

Lower ankle-brachial index is related to worse cognitive performance in old age
Laukka Ej, Starr Jm, Deary Ij
Neuropsychology 2014;28(2):281-9

The benefits of staying active in old age: physical activity counteracts the negative influence of PICALM, BIN1, and CLU risk alleles on episodic memory functioning
Ferencz B, Laukka Ej, Welmer Ak, Kalpouzos G, Angleman S, Keller L, et al
Psychology and aging 2014;29(2):440-9

Walking speed, processing speed, and dementia: a population-based longitudinal study
Welmer Ak, Rizzuto D, Qiu C, Caracciolo B, Laukka Ej
The journals of gerontology. Series A, Biological sciences and medical sciences 2014;69(12):1503-10

Associations between white matter microstructure and cognitive performance in old and very old age
Laukka Ej, Lövdén M, Kalpouzos G, Li Tq, Jonsson T, Wahlund Lo, et al
PloS one 2013;8(11):e81419-

Genetic effects on old-age cognitive functioning: a population-based study
Laukka Ej, Lövdén M, Herlitz A, Karlsson S, Ferencz B, Pantzar A, et al
Psychology and aging 2013;28(1):262-74

The dimensionality of between-person differences in white matter microstructure in old age
Lövdén M, Laukka Ej, Rieckmann A, Kalpouzos G, Li Tq, Jonsson T, et al
Human brain mapping 2013;34(6):1386-98

The influence of APOE and TOMM40 polymorphisms on hippocampal volume and episodic memory in old age
Ferencz B, Laukka Ej, Lövdén M, Kalpouzos G, Keller L, Graff C, et al
Frontiers in human neuroscience 2013;7():198-

Preclinical Cognitive Trajectories Differ for Alzheimer's Disease and Vascular Dementia
Laukka Ej, Macdonald Sws, Fratiglioni L, Backman L
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY 2012;18(2):191-9

Effects of intensified metabolic control on CNS function in type 2 diabetes
Cooray G, Nilsson E, Wahlin A, Laukka Ej, Brismar K, Brismar T
PSYCHONEUROENDOCRINOLOGY 2011;36(1):77-86

Onset and Rate of Cognitive Change Before Dementia Diagnosis: Findings From Two Swedish Population-Based Longitudinal Studies
Thorvaldsson V, Macdonald Sws, Fratiglioni L, Winblad B, Kivipelto M, Laukka Ej, et al
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY 2011;17(1):154-62

The Influence of Vascular Disease on Cognitive Performance in the Preclinical and Early Phases of Alzheimer's Disease
Laukka Ej, Fratiglioni L, Backman L
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2010;29(6):498-503

Prospective and retrospective memory in Alzheimer's disease and vascular dementia: Similar patterns of impairment
Livner A, Laukka Ej, Karlsson S, Backman L
JOURNAL OF THE NEUROLOGICAL SCIENCES 2009;283(1-2):235-9

Terminal-decline effects for select cognitive tasks after controlling for preclinical dementia
Laukka Ej, Macdonald Sws, Backman L
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY 2008;16(5):355-65

Contrasting cognitive trajectories of impending death and preclinical dementia in the very old
Laukka Ej, Macdonald Ws, Backman L
NEUROLOGY 2006;66(6):833-8

Differential verbal fluency deficits in the preclinical stages of Alzheimer's disease and vascular dementia
Jones S, Laukka Ej, Backman L
CORTEX 2006;42(3):347-55

Cognitive impairment in preclinical Alzheimer's disease: A meta-analysis
Backman L, Jones S, Berger Ak, Laukka Ej, Small Bj
NEUROPSYCHOLOGY 2005;19(4):520-31

A preclinical phase in vascular dementia: Cognitive impairment three years before diagnosis
Jones S, Laukka Ej, Small Bj, Fratiglioni L, Backmana L
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2004;18(3-4):233-9

Cognitive functioning in preclinical vascular dementia - A 6-year follow-up
Laukka Ej, Jones S, Fratiglioni L, Backman L
STROKE 2004;35(8):1805-9

Multiple cognitive deficits during the transition to Alzheimer's disease
Backman L, Jones S, Berger Ak, Laukka Ej, Small Bj
JOURNAL OF INTERNAL MEDICINE 2004;256(3):195-204

Similar patterns of cognitive deficits in the preclinical phases of vascular dementia and Alzheimer's disease
Laukka Ej, Jones S, Small Bj, Fratiglioni L, Backman L
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY 2004;10(3):382-91

Cognitive deficits in preclinical Alzheimer's disease
Small Bj, Mobly Jl, Laukka Ej, Jones S, Backman L
ACTA NEUROLOGICA SCANDINAVICA 2003;:29-33

Influences of preclinical dementia and impending death on the magnitude of age-related cognitive deficits
Backman L, Laukka Ej, Wahlin A, Small Bj, Fratiglioni L
PSYCHOLOGY AND AGING 2002;17(3):435-42

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